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Travis S. Young - Publications

Affiliations: 
California Institute for Biomedical Research 
Area:
Immuno-oncology
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38/46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pennell CA, Campbell H, Storlie MD, Bolivar-Wagers S, Osborn MJ, Refaeli Y, Jensen M, Viaud S, Young TS, Blazar BR. Human CD19-specific switchable CAR T-cells are efficacious as constitutively active CAR T-cells but cause less morbidity in a mouse model of human CD19 malignancy. Journal For Immunotherapy of Cancer. 10. PMID 36521930 DOI: 10.1136/jitc-2022-005934  0.784
2021 McGraw JM, Thelen F, Hampton EN, Bruno NE, Young TS, Havran WL, Witherden DA. JAML promotes CD8 and γδ T cell antitumor immunity and is a novel target for cancer immunotherapy. The Journal of Experimental Medicine. 218. PMID 34427588 DOI: 10.1084/jem.20202644  0.716
2021 Lee SC, Ma JSY, Kim MS, Laborda E, Choi SH, Hampton EN, Yun H, Nunez V, Muldong MT, Wu CN, Ma W, Kulidjian AA, Kane CJ, Klyushnichenko V, Woods AK, ... ... Young TS, et al. A PSMA-targeted bispecific antibody for prostate cancer driven by a small-molecule targeting ligand. Science Advances. 7. PMID 34380625 DOI: 10.1126/sciadv.abi8193  0.794
2021 Garnar-Wortzel L, Bishop TR, Kitamura S, Milosevich N, Asiaban JN, Zhang X, Zheng Q, Chen E, Ramos AR, Ackerman CJ, Hampton EN, Chatterjee AK, Young TS, Hull MV, Sharpless KB, et al. Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia. Acs Central Science. 7: 815-830. PMID 34079898 DOI: 10.1021/acscentsci.0c01550  0.783
2020 Chin EN, Yu C, Vartabedian VF, Jia Y, Kumar M, Gamo AM, Vernier W, Ali SH, Kissai M, Lazar DC, Nguyen N, Pereira LE, Benish B, Woods AK, Joseph SB, ... ... Young TS, et al. Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science (New York, N.Y.). 369: 993-999. PMID 32820126 DOI: 10.1126/Science.Abb4255  0.808
2020 Asiaban JN, Milosevich N, Chen E, Bishop TR, Wang J, Zhang Y, Ackerman CJ, Hampton E, Young TS, Hull M, Cravatt BF, Erb MA. Cell-based ligand discovery for the ENL YEATS domain. Acs Chemical Biology. PMID 32176478 DOI: 10.1021/Acschembio.0C00124  0.789
2018 Viaud S, Ma JSY, Hardy IR, Hampton EN, Benish B, Sherwood L, Nunez V, Ackerman CJ, Khialeeva E, Weglarz M, Lee SC, Woods AK, Young TS. Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory. Proceedings of the National Academy of Sciences of the United States of America. PMID 30373813 DOI: 10.1073/Pnas.1810060115  0.796
2018 Raj D, Yang MH, Rodgers D, Hampton EN, Begum J, Mustafa A, Lorizio D, Garces I, Propper D, Kench JG, Young TS, Aicher A, Heeschen C. Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma. Gut. PMID 30121627 DOI: 10.1136/Gutjnl-2018-316595  0.836
2018 Zhang G, Baidin V, Pahil KS, Moison E, Tomasek D, Ramadoss NS, Chatterjee AK, McNamara CW, Young TS, Schultz PG, Meredith TC, Kahne D. Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735709 DOI: 10.1073/Pnas.1804670115  0.779
2018 Supekova L, Zambaldo C, Choi S, Lim R, Luo X, Kazane SA, Young TS, Schultz PG. The genetic incorporation of p-azidomethyl-l-phenylalanine into proteins in yeast. Bioorganic & Medicinal Chemistry Letters. PMID 29625824 DOI: 10.1016/J.Bmcl.2018.03.055  0.761
2018 Laborda E, Young TS. Strategies to Control CAR-T Cell Therapy: Perspective on Next-Generation CARs Cell and Gene Therapy Insights. 4: 275-285. DOI: 10.18609/cgti.2018.028  0.301
2018 Huang H, Viaud S, Theofilopoulos AN, Young TS, Kono DH. AI-04 Immunotherapy for lupus in a mouse model to define pathogenesis and therapeutic targeting Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Lsm.4  0.794
2017 Laborda E, Mazagova M, Shao S, Wang X, Quirino H, Woods AK, Hampton EN, Rodgers DT, Kim CH, Schultz PG, Young TS. Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia. International Journal of Molecular Sciences. 18. PMID 29077054 DOI: 10.3390/Ijms18112259  0.813
2017 Tran HL, Lexa KW, Julien O, Young TS, Walsh CT, Jacobson MP, Wells JA. SAR and molecular mechanics reveal the importance of ring entropy in the biosynthesis and activity of a natural product. Journal of the American Chemical Society. PMID 28170244 DOI: 10.1021/Jacs.6B10792  0.564
2017 Laborda E, Hampton EN, Lee SC, Woods AK, Young TS. A Novel Switchable CAR-T Platform for Acute Lymphoblastic Leukemia Treatment Blood. 130: 3890-3890. DOI: 10.1182/Blood.V130.Suppl_1.3890.3890  0.756
2017 Yu S, Pearson A, Lim R, Rodgers D, Li S, Parker H, Weglarz M, Hampton E, Bollong M, Shen J, Zumbaldo C, Wang D, Woods A, Wright T, Schultz P, ... ... Young T, et al. P-262 A PDE4 Inhibitor-antibody Conjugate for Treating Ulcerative Colitis Inflammatory Bowel Diseases. 23. DOI: 10.1097/01.Mib.0000512805.98510.C0  0.739
2016 Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, ... ... Young TS, et al. Targeted delivery of an anti-inflammatory PDE4 inhibitor to immune cells via an antibody-drug conjugate. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27731313 DOI: 10.1038/Mt.2016.175  0.755
2016 Liu T, Wang Y, Luo X, Li J, Reed SA, Xiao H, Young TS, Schultz PG. Enhancing protein stability with extended disulfide bonds. Proceedings of the National Academy of Sciences of the United States of America. 113: 5910-5. PMID 27162342 DOI: 10.1073/Pnas.1605363113  0.76
2016 Cao Y, Rodgers DT, Du J, Ahmad I, Hampton EN, Ma JS, Mazagova M, Choi SH, Yun HY, Xiao H, Yang P, Luo X, Lim RK, Pugh HM, Wang F, ... ... Young TS, et al. Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer. Angewandte Chemie (International Ed. in English). 55: 7520-4. PMID 27145250 DOI: 10.1002/Anie.201601902  0.768
2016 Luo X, Zambaldo C, Liu T, Zhang Y, Xuan W, Wang C, Reed SA, Yang PY, Wang RE, Javahishvili T, Schultz PG, Young TS. Recombinant thiopeptides containing noncanonical amino acids. Proceedings of the National Academy of Sciences of the United States of America. 113: 3615-20. PMID 26976568 DOI: 10.1073/Pnas.1602733113  0.763
2016 Rodgers DT, Mazagova M, Hampton EN, Cao Y, Ramadoss NS, Hardy IR, Schulman A, Du J, Wang F, Singer O, Ma J, Nunez V, Shen J, Woods AK, Wright TM, ... ... Young TS, et al. Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies. Proceedings of the National Academy of Sciences of the United States of America. 113: E459-68. PMID 26759369 DOI: 10.1073/Pnas.1524155113  0.794
2016 Ma JS, Kim JY, Kazane SA, Choi SH, Yun HY, Kim MS, Rodgers DT, Pugh HM, Singer O, Sun SB, Fonslow BR, Kochenderfer JN, Wright TM, Schultz PG, Young TS, et al. Versatile strategy for controlling the specificity and activity of engineered T cells. Proceedings of the National Academy of Sciences of the United States of America. 113: E450-8. PMID 26759368 DOI: 10.1073/Pnas.1524193113  0.807
2015 Lampkowski JS, Villa JK, Young TS, Young DD. Development and Optimization of Glaser-Hay Bioconjugations. Angewandte Chemie (International Ed. in English). PMID 26088803 DOI: 10.1002/Anie.201502676  0.528
2015 Ramadoss NS, Schulman AD, Choi SH, Rodgers DT, Kazane SA, Kim CH, Lawson BR, Young TS. An anti-B cell maturation antigen bispecific antibody for multiple myeloma. Journal of the American Chemical Society. 137: 5288-91. PMID 25826669 DOI: 10.1021/Jacs.5B01876  0.815
2015 Wang RE, Liu T, Wang Y, Cao Y, Du J, Luo X, Deshmukh V, Kim CH, Lawson BR, Tremblay MS, Young TS, Kazane SA, Wang F, Schultz PG. An immunosuppressive antibody-drug conjugate. Journal of the American Chemical Society. 137: 3229-32. PMID 25699419 DOI: 10.1021/Jacs.5B00620  0.818
2015 Kim MS, Ma JS, Yun H, Cao Y, Kim JY, Chi V, Wang D, Woods A, Sherwood L, Caballero D, Gonzalez J, Schultz PG, Young TS, Kim CH. Redirection of genetically engineered CAR-T cells using bifunctional small molecules. Journal of the American Chemical Society. 137: 2832-5. PMID 25692571 DOI: 10.1021/Jacs.5B00106  0.84
2015 Young TS. Biosynthesis and Directed Evolution of Unnatural Peptides and Proteins Reviews in Cell Biology and Molecular Medicine. 1: 268-307. DOI: 10.1002/3527600906.Mcb.201500021  0.315
2013 Malcolmson SJ, Young TS, Ruby JG, Skewes-Cox P, Walsh CT. The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffolds. Proceedings of the National Academy of Sciences of the United States of America. 110: 8483-8. PMID 23650400 DOI: 10.1073/Pnas.1307111110  0.723
2012 Young TS, Dorrestein PC, Walsh CT. Codon randomization for rapid exploration of chemical space in thiopeptide antibiotic variants. Chemistry & Biology. 19: 1600-10. PMID 23261603 DOI: 10.1016/J.Chembiol.2012.10.013  0.632
2012 Bowers AA, Acker MG, Young TS, Walsh CT. Generation of thiocillin ring size variants by prepeptide gene replacement and in vivo processing by Bacillus cereus. Journal of the American Chemical Society. 134: 10313-6. PMID 22686940 DOI: 10.1021/ja302820x  0.674
2012 Walsh CT, Malcolmson SJ, Young TS. Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks. Acs Chemical Biology. 7: 429-42. PMID 22206579 DOI: 10.1021/Cb200518N  0.744
2012 Tianero MD, Donia MS, Young TS, Schultz PG, Schmidt EW. Ribosomal route to small-molecule diversity. Journal of the American Chemical Society. 134: 418-25. PMID 22107593 DOI: 10.1021/Ja208278K  0.575
2011 Young TS, Walsh CT. Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans. Proceedings of the National Academy of Sciences of the United States of America. 108: 13053-8. PMID 21788474 DOI: 10.1073/Pnas.1110435108  0.566
2011 Young TS, Young DD, Ahmad I, Louis JM, Benkovic SJ, Schultz PG. Evolution of cyclic peptide protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 11052-6. PMID 21690365 DOI: 10.1073/Pnas.1108045108  0.776
2011 Young DD, Young TS, Jahnz M, Ahmad I, Spraggon G, Schultz PG. An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity. Biochemistry. 50: 1894-900. PMID 21280675 DOI: 10.1021/Bi101929E  0.762
2010 Young TS, Schultz PG. Beyond the canonical 20 amino acids: expanding the genetic lexicon. The Journal of Biological Chemistry. 285: 11039-44. PMID 20147747 DOI: 10.1074/Jbc.R109.091306  0.582
2010 Young TS, Ahmad I, Yin JA, Schultz PG. An enhanced system for unnatural amino acid mutagenesis in E. coli. Journal of Molecular Biology. 395: 361-74. PMID 19852970 DOI: 10.1016/J.Jmb.2009.10.030  0.777
2009 Young TS, Ahmad I, Brock A, Schultz PG. Expanding the genetic repertoire of the methylotrophic yeast Pichia pastoris. Biochemistry. 48: 2643-53. PMID 19265424 DOI: 10.1021/Bi802178K  0.775
Low-probability matches (unlikely to be authored by this person)
2012 Davies BW, Bogard RW, Young TS, Mekalanos JJ. Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence. Cell. 149: 358-70. PMID 22500802 DOI: 10.1016/J.Cell.2012.01.053  0.255
2013 Koppal SJ, Gkioulekas I, Young T, Park H, Crozier KB, Barrows GL, Zickler T. Toward wide-angle microvision sensors. Ieee Transactions On Pattern Analysis and Machine Intelligence. 35: 2982-96. PMID 24136435 DOI: 10.1109/Tpami.2013.22  0.212
2002 Owen RM, Gestwicki JE, Young T, Kiessling LL. Synthesis and applications of end-labeled neoglycopolymers. Organic Letters. 4: 2293-6. PMID 12098230 DOI: 10.1021/Ol0259239  0.148
2002 Young T, Kiessling LL. A strategy for the synthesis of sulfated peptides. Angewandte Chemie (International Ed. in English). 41: 3449-51. PMID 12298060 DOI: 10.1002/1521-3773(20020916)41:18<3449::Aid-Anie3449>3.0.Co;2-U  0.108
2004 Nagy AL, Young T, Neriani K. Combining information in different color-coding mechanisms to facilitate visual search. Vision Research. 44: 2971-80. PMID 15381000 DOI: 10.1016/j.visres.2004.05.031  0.073
2001 Liu FG, Miyamoto MM, Freire NP, Ong PQ, Tennant MR, Young TS, Gugel KF. Molecular and morphological supertrees for eutherian (placental) mammals. Science (New York, N.Y.). 291: 1786-9. PMID 11230694 DOI: 10.1126/SCIENCE.1056346  0.063
2005 Young T, Mei F, Liu J, Bast RC, Kurosky A, Cheng X. Proteomics analysis of H-RAS-mediated oncogenic transformation in a genetically defined human ovarian cancer model. Oncogene. 24: 6174-84. PMID 15940260 DOI: 10.1038/Sj.Onc.1208753  0.059
2020 Young T, Chen F, Burba CM. A Quantitative Investigation of Ion Clusters in a Double Salt Ionic Liquid by Both Vibrational Spectroscopy and Molecular Dynamics Simulation. The Journal of Physical Chemistry. B. PMID 32310669 DOI: 10.1021/Acs.Jpcb.0C01457  0.027
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