Mary Fedarko Roberts - Publications

Chemistry Boston College, Newton, MA, United States 
31P for phospholipase assays and substrate characterization, indirect detection of 13C or 15N uptake and turnover in archaea and some mammalian cells

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Roberts MF, Cai J, V Natarajan S, Khan HM, Reuter N, Gershenson A, Redfield AG. Phospholipids in Motion: High-Resolution P NMR Field Cycling Studies. The Journal of Physical Chemistry. B. PMID 34320805 DOI: 10.1021/acs.jpcb.1c02105  0.557
2020 Rosenberg MM, Yao T, Patton GC, Redfield AG, Roberts MF, Hedstrom L. Enzyme-substrate-cofactor dynamical networks revealed by high resolution field cycling relaxometry. Biochemistry. PMID 32479091 DOI: 10.1021/Acs.Biochem.0C00212  0.369
2019 Waheed Q, Khan HM, He T, Roberts MF, Gershenson A, Reuter N. Interfacial Aromatics Mediating Cation-Π Interactions with Choline Containing Lipids Can Contribute As Much To Peripheral Protein Affinity for Membranes as Aromatics Inserted Below the Phosphates. The Journal of Physical Chemistry Letters. PMID 31246477 DOI: 10.1021/Acs.Jpclett.9B01639  0.34
2018 Roberts MF, Khan HM, Goldstein R, Reuter N, Gershenson A. Search and Subvert: Minimalist Bacterial Phosphatidylinositol-Specific Phospholipase C Enzymes. Chemical Reviews. PMID 30148347 DOI: 10.1021/Acs.Chemrev.8B00208  0.413
2018 Rosenberg MM, Redfield AG, Roberts M, Hedstrom L. Dynamic characteristics of GMP reductase complexes revealed by high resolutionP field cycling NMR relaxometry. Biochemistry. PMID 29547266 DOI: 10.1021/Acs.Biochem.8B00142  0.357
2016 Rosenberg MM, Redfield AG, Roberts MF, Hedstrom L. Substrate and Cofactor Dynamics on Guanosine Monophosphate Reductase Probed by High Resolution Field Cycling 31P NMR Relaxometry. The Journal of Biological Chemistry. PMID 27613871 DOI: 10.1074/Jbc.M116.739516  0.35
2016 Khan HM, He T, Fuglebakk E, Grauffel C, Yang B, Roberts MF, Gershenson A, Reuter N. A Role for Weak Electrostatic Interactions in Peripheral Membrane Protein Binding. Biophysical Journal. 110: 1367-78. PMID 27028646 DOI: 10.1016/J.Bpj.2016.02.020  0.36
2016 Huang Q, Gershenson A, Roberts MF. Recombinant broad-range phospholipase C from Listeria monocytogenes exhibits optimal activity at acidic pH. Biochimica Et Biophysica Acta. PMID 26976751 DOI: 10.1016/J.Bbapap.2016.03.008  0.605
2015 He T, Gershenson A, Eyles SJ, Lee YJ, Liu WR, Wang J, Gao J, Roberts MF. Fluorinated aromatic amino acids distinguish cation-π interactions from membrane insertion. The Journal of Biological Chemistry. PMID 26092728 DOI: 10.1074/Jbc.M115.668343  0.339
2015 Mitchell G, Ge L, Huang Q, Chen C, Kianian S, Roberts MF, Schekman R, Portnoy DA. Avoidance of autophagy mediated by PlcA or ActA is required for Listeria monocytogenes growth in macrophages. Infection and Immunity. 83: 2175-84. PMID 25776746 DOI: 10.1128/Iai.00110-15  0.5
2015 Yang B, Pu M, Khan HM, Friedman L, Reuter N, Roberts MF, Gershenson A. Quantifying transient interactions between Bacillus phosphatidylinositol-specific phospholipase-C and phosphatidylcholine-rich vesicles. Journal of the American Chemical Society. 137: 14-7. PMID 25517221 DOI: 10.1021/Ja508631N  0.556
2015 Wei Y, Stec B, Redfield AG, Weerapana E, Roberts MF. Phospholipid-binding sites of phosphatase and tensin homolog (PTEN): exploring the mechanism of phosphatidylinositol 4,5-bisphosphate activation. The Journal of Biological Chemistry. 290: 1592-606. PMID 25429968 DOI: 10.1074/Jbc.M114.588590  0.598
2015 He T, Khan HM, Grauffel C, Reuter N, Gershenson A, Roberts MF. Identifying the Choline-Cation Tyrosine-PI Interactions of an Amphitropic Protein Biophysical Journal. 108: 256a. DOI: 10.1016/J.Bpj.2014.11.1414  0.413
2015 Khan HM, Grauffel C, Roberts MF, Gershenson A, Reuter N. Interplay between Electrostatics and Cation-PI Interactions Governs the Specific Membrane Binding of Phosphatidylinositol-Specific Phospholipase-C Biophysical Journal. 108: 248a. DOI: 10.1016/J.Bpj.2014.11.1374  0.346
2014 Gradziel CS, Wang Y, Stec B, Redfield AG, Roberts MF. Cytotoxic amphiphiles and phosphoinositides bind to two discrete sites on the Akt1 PH domain. Biochemistry. 53: 462-72. PMID 24383815 DOI: 10.1021/Bi401720V  0.48
2014 Yang B, Roberts MF, Gershenson A. Revealing Transient Interactions Between Phosphatidylinositol-Specific Phospholipase C and Phosphatidylcholine-Rich Lipid Vesicles Biophysical Journal. 106: 716a. DOI: 10.1016/J.Bpj.2013.11.3957  0.337
2013 Cai J, Guo S, Lomasney JW, Roberts MF. Ca2+-independent binding of anionic phospholipids by phospholipase C δ1 EF-hand domain. The Journal of Biological Chemistry. 288: 37277-88. PMID 24235144 DOI: 10.1074/Jbc.M113.512186  0.671
2013 Kurnasov OV, Luk HJ, Roberts MF, Stec B. Structure of the inositol-1-phosphate cytidylyltransferase from Thermotoga maritima. Acta Crystallographica. Section D, Biological Crystallography. 69: 1808-17. PMID 23999304 DOI: 10.1107/S0907444913015278  0.43
2013 Cheng J, Goldstein R, Gershenson A, Stec B, Roberts MF. The cation-π box is a specific phosphatidylcholine membrane targeting motif. The Journal of Biological Chemistry. 288: 14863-73. PMID 23576432 DOI: 10.1074/Jbc.M113.466532  0.341
2013 Grauffel C, Yang B, He T, Roberts MF, Gershenson A, Reuter N. Cation-π interactions as lipid-specific anchors for phosphatidylinositol-specific phospholipase C. Journal of the American Chemical Society. 135: 5740-50. PMID 23506313 DOI: 10.1021/Ja312656V  0.358
2013 Cheng J, Karri S, Grauffel C, Wang F, Reuter N, Roberts MF, Wintrode PL, Gershenson A. Does changing the predicted dynamics of a phospholipase C alter activity and membrane binding? Biophysical Journal. 104: 185-95. PMID 23332071 DOI: 10.1016/J.Bpj.2012.11.015  0.429
2013 Grauffel C, He T, Yang B, Wintrode PL, Gershenson A, Roberts MF, Reuter N. Cation-PI Interactions as Specific Anchors for B. Thurigiensis Phosphoinositol-Specific Phospholipase-C Binding to Phosphatidylcholine Bilayer Biophysical Journal. 104: 536a. DOI: 10.1016/J.Bpj.2012.11.2969  0.377
2013 He T, Yang B, Grauffel C, Reuter N, Gershenson A, Roberts MF. Probing for π-Cation Interactions in the Binding of B. Thuringiensis Phosphatidylinositol-Specific Phospholipase C Phosphatidylcholine-Rich Vesicles Biophysical Journal. 104: 363a-364a. DOI: 10.1016/J.Bpj.2012.11.2018  0.372
2012 Cheng J, Goldstein R, Stec B, Gershenson A, Roberts MF. Competition between anion binding and dimerization modulates Staphylococcus aureus phosphatidylinositol-specific phospholipase C enzymatic activity. The Journal of Biological Chemistry. 287: 40317-27. PMID 23038258 DOI: 10.1074/Jbc.M112.395277  0.488
2012 Goldstein R, Cheng J, Stec B, Roberts MF. Structure of the S. aureus PI-specific phospholipase C reveals modulation of active site access by a titratable π-cation latched loop. Biochemistry. 51: 2579-87. PMID 22390775 DOI: 10.1021/Bi300057Q  0.41
2012 Cheng J, Roberts MF, Gershenson A. Identifying Motifs for Phosphatidylcholine Activation of Bacterial Phosphatidylinositol-Specific Phospholipase C Enzymes Biophysical Journal. 102: 79a-80a. DOI: 10.1016/J.Bpj.2011.11.460  0.451
2012 Grauffel C, He T, Yang B, Guo S, Wintrode PL, Gershenson A, Roberts MF, Reuter N. Anchoring of PI-PLC to DMPC Bilayers Involves Specific Cation-PI Interactions Biophysical Journal. 102: 78a-79a. DOI: 10.1016/J.Bpj.2011.11.455  0.376
2012 Wei Y, Roberts MF. Probing the Activator and Hydrophobic Substrate Binding Sites of PTEN by 31P NMR Biophysical Journal. 102: 494a. DOI: 10.1016/J.Bpj.2011.11.2707  0.599
2012 Goldstein R, Cheng J, Roberts M. Structural Studies of Phosphatidylinositol-Specific Phospholipase C from S. Aureus; An Intramolecular π-Cation Latch Biophysical Journal. 102: 251a. DOI: 10.1016/J.Bpj.2011.11.1385  0.384
2011 Neelon K, Roberts MF, Stec B. Crystal structure of a trapped catalytic intermediate suggests that forced atomic proximity drives the catalysis of mIPS. Biophysical Journal. 101: 2816-24. PMID 22261071 DOI: 10.1016/J.Bpj.2011.10.038  0.786
2011 Strelko CL, Lu W, Dufort FJ, Seyfried TN, Chiles TC, Rabinowitz JD, Roberts MF. Itaconic acid is a mammalian metabolite induced during macrophage activation. Journal of the American Chemical Society. 133: 16386-9. PMID 21919507 DOI: 10.1021/Ja2070889  0.749
2011 Stec B, Roberts MF, Kantrowitz ER. Trapping and visualization of catalytic intermediates Acta Crystallographica Section a Foundations of Crystallography. 67: C80-C80. DOI: 10.1107/S0108767311098059  0.514
2011 Wei Y, Roberts MF. 31P NMR Studies of Active Site and Activator Site Ligands Binding to PTEN Biophysical Journal. 100: 552a. DOI: 10.1016/J.Bpj.2010.12.3211  0.596
2010 Pu M, Orr A, Redfield AG, Roberts MF. Defining specific lipid binding sites for a peripheral membrane protein in situ using subtesla field-cycling NMR. The Journal of Biological Chemistry. 285: 26916-22. PMID 20576615 DOI: 10.1074/Jbc.M110.123083  0.594
2010 Wang Q, Wei Y, Mottamal M, Roberts MF, Krilov G. Understanding the stereospecific interactions of 3-deoxyphosphatidylinositol derivatives with the PTEN phosphatase domain. Journal of Molecular Graphics & Modelling. 29: 102-14. PMID 20538496 DOI: 10.1016/J.Jmgm.2010.05.004  0.546
2010 Li Z, Stieglitz KA, Shrout AL, Wei Y, Weis RM, Stec B, Roberts MF. Mobile loop mutations in an archaeal inositol monophosphatase: modulating three-metal ion assisted catalysis and lithium inhibition. Protein Science : a Publication of the Protein Society. 19: 309-18. PMID 20027624 DOI: 10.1002/Pro.315  0.55
2010 Shelton LM, Strelko CL, Roberts MF, Seyfried TN. Abstract 53: Krebs cycle substrate-level phosphorylation drives metastatic cancer cells Cancer Research. 70: 53-53. DOI: 10.1158/1538-7445.Am10-53  0.757
2009 Pu M, Feng J, Redfield AG, Roberts MF. Enzymology with a spin-labeled phospholipase C: soluble substrate binding by 31P NMR from 0.005 to 11.7 T. Biochemistry. 48: 8282-4. PMID 19663462 DOI: 10.1021/Bi901190J  0.622
2009 Pu M, Roberts MF, Gershenson A. Fluorescence correlation spectroscopy of phosphatidylinositol-specific phospholipase C monitors the interplay of substrate and activator lipid binding. Biochemistry. 48: 6835-45. PMID 19548649 DOI: 10.1021/Bi900633P  0.641
2009 Longo CM, Wei Y, Roberts MF, Miller SJ. Asymmetric Syntheses of L,L- and L,D-di-myo-inositol-1,1'-phosphate and their behavior as stabilizers of enzyme activity at extreme temperatures. Angewandte Chemie (International Ed. in English). 48: 4158-61. PMID 19425028 DOI: 10.1002/Anie.200900480  0.521
2009 Shi X, Shao C, Zhang X, Zambonelli C, Redfield AG, Head JF, Seaton BA, Roberts MF. Modulation of Bacillus thuringiensis phosphatidylinositol-specific phospholipase C activity by mutations in the putative dimerization interface. The Journal of Biological Chemistry. 284: 15607-18. PMID 19369255 DOI: 10.1074/Jbc.M901601200  0.614
2009 Pu M, Fang X, Redfield AG, Gershenson A, Roberts MF. Correlation of vesicle binding and phospholipid dynamics with phospholipase C activity: insights into phosphatidylcholine activation and surface dilution inhibition. The Journal of Biological Chemistry. 284: 16099-107. PMID 19336401 DOI: 10.1074/Jbc.M809600200  0.659
2009 Chen W, Goldfine H, Ananthanarayanan B, Cho W, Roberts MF. Listeria monocytogenes phosphatidylinositol-specific phospholipase C: Kinetic activation and homing in on different interfaces. Biochemistry. 48: 3578-92. PMID 19281241 DOI: 10.1021/Bi802312D  0.483
2009 Sivanandam VN, Cai J, Redfield AG, Roberts MF. Phosphatidylcholine "wobble" in vesicles assessed by high-resolution 13C field cycling NMR spectroscopy. Journal of the American Chemical Society. 131: 3420-1. PMID 19243091 DOI: 10.1021/Ja808431H  0.606
2009 Pu M, Roberts MF, Gershenson A. FCS of Mutated Phosphatidylinositol-specific Phospholipase C Enzymes Monitors the Interplay of Substrate and Activator Lipid Binding Biophysical Journal. 96: 612a. DOI: 10.1016/J.Bpj.2008.12.3237  0.66
2009 Shi X, Roberts MF, Meklemburg R, Wintrode PL. H/D Exchange Provides Insights Into The Orientation Of Bacillus Thuringiensis Pi-phospholipase C Binding To Mixed Component Vesicles Biophysical Journal. 96: 612a. DOI: 10.1016/J.Bpj.2008.12.3235  0.548
2009 Cai J, Crouch EC, Seaton BA, Roberts MF. Interaction of Lung Surfactant Protein A with Phosphatidylcholine Vesicles Biophysical Journal. 96: 611a. DOI: 10.1016/J.Bpj.2008.12.3231  0.611
2009 Wei Y, Wang YK, Xu Y, Miller S, Roberts MF. PTEN Inhibition Study by Synthetic 3-Deoxy-PI Derivatives Biophysical Journal. 96: 441a. DOI: 10.1016/J.Bpj.2008.12.2262  0.587
2009 Guo S, Roberts MF. Role of Rim Tyr/Trp Residues in Interfacial Activation of Phospholipase C Enzymes Biophysical Journal. 96: 439a-440a. DOI: 10.1016/J.Bpj.2008.12.2256  0.466
2008 Wang YK, Chen W, Blair D, Pu M, Xu Y, Miller SJ, Redfield AG, Chiles TC, Roberts MF. Insights into the structural specificity of the cytotoxicity of 3-deoxyphosphatidylinositols. Journal of the American Chemical Society. 130: 7746-55. PMID 18498165 DOI: 10.1021/Ja710348R  0.662
2008 Guo S, Zhang X, Seaton BA, Roberts MF. Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C. Biochemistry. 47: 4201-10. PMID 18345643 DOI: 10.1021/Bi702269U  0.409
2007 Wang Y, Stieglitz KA, Bubunenko M, Court DL, Stec B, Roberts MF. The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli. The Journal of Biological Chemistry. 282: 26989-96. PMID 17652087 DOI: 10.1074/Jbc.M701210200  0.491
2007 Stieglitz KA, Roberts MF, Li W, Stec B. Crystal structure of the tetrameric inositol 1-phosphate phosphatase (TM1415) from the hyperthermophile, Thermotoga maritima. The Febs Journal. 274: 2461-9. PMID 17419729 DOI: 10.1111/J.0014-2956.2007.05779.X  0.384
2007 Crouch E, McDonald B, Smith K, Roberts M, Mealy T, Seaton B, Head J. Critical role of Arg/Lys343 in the species-dependent recognition of phosphatidylinositol by pulmonary surfactant protein D. Biochemistry. 46: 5160-9. PMID 17417879 DOI: 10.1021/Bi700037X  0.343
2007 Rodionov DA, Kurnasov OV, Stec B, Wang Y, Roberts MF, Osterman AL. Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate. Proceedings of the National Academy of Sciences of the United States of America. 104: 4279-84. PMID 17360515 DOI: 10.1073/Pnas.0609279104  0.343
2007 Shao C, Shi X, Wehbi H, Zambonelli C, Head JF, Seaton BA, Roberts MF. Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C. The Journal of Biological Chemistry. 282: 9228-35. PMID 17213187 DOI: 10.1074/Jbc.M610918200  0.803
2006 Faber AC, Dufort FJ, Blair D, Wagner D, Roberts MF, Chiles TC. Inhibition of phosphatidylinositol 3-kinase-mediated glucose metabolism coincides with resveratrol-induced cell cycle arrest in human diffuse large B-cell lymphomas. Biochemical Pharmacology. 72: 1246-56. PMID 16979140 DOI: 10.1016/J.Bcp.2006.08.009  0.338
2006 Wang YK, Morgan A, Stieglitz K, Stec B, Thompson B, Miller SJ, Roberts MF. The temperature dependence of the inositol monophosphatase Km correlates with accumulation of di-myo-inositol 1,1'-phosphate in Archaeoglobus fulgidus. Biochemistry. 45: 3307-14. PMID 16519525 DOI: 10.1021/Bi052467Y  0.51
2005 Neelon K, Schreier HJ, Meekins H, Robinson PM, Roberts MF. Compatible solute effects on thermostability of glutamine synthetase and aspartate transcarbamoylase from Methanococcus jannaschii. Biochimica Et Biophysica Acta. 1753: 164-73. PMID 16168724 DOI: 10.1016/J.Bbapap.2005.08.009  0.791
2005 Zambonelli C, Roberts MF. Non-HKD phospholipase D enzymes: new players in phosphatidic acid signaling? Progress in Nucleic Acid Research and Molecular Biology. 79: 133-81. PMID 16096028 DOI: 10.1016/S0079-6603(04)79003-0  0.411
2005 Kobayashi M, Gryczynski Z, Lukomska J, Feng J, Roberts MF, Lakowicz JR, Lomasney JW. Spectroscopic characterization of the EF-hand domain of phospholipase C delta1: identification of a lipid interacting domain. Archives of Biochemistry and Biophysics. 440: 191-203. PMID 16054586 DOI: 10.1016/J.Abb.2005.06.014  0.322
2005 Feng J, Roberts MF, Drin G, Scarlata S. Dissection of the steps of phospholipase C beta 2 activity that are enhanced by G beta gamma subunits. Biochemistry. 44: 2577-84. PMID 15709770 DOI: 10.1021/Bi0482607  0.457
2005 Neelon K, Wang Y, Stec B, Roberts MF. Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase. The Journal of Biological Chemistry. 280: 11475-82. PMID 15653679 DOI: 10.1074/Jbc.M500469200  0.806
2005 Stieglitz KA, Yang H, Roberts MF, Stec B. Reaching for mechanistic consensus across life kingdoms: structure and insights into catalysis of the myo-inositol-1-phosphate synthase (mIPS) from Archaeoglobus fulgidus. Biochemistry. 44: 213-24. PMID 15628862 DOI: 10.1021/Bi048267O  0.639
2004 Yang H, Roberts MF. Expression and characterization of a heterodimer of Streptomyces chromofuscus phospholipase D. Biochimica Et Biophysica Acta. 1703: 43-51. PMID 15588701 DOI: 10.1016/J.Bbapap.2004.09.014  0.626
2004 Morgan AJ, Wang YK, Roberts MF, Miller SJ. Chemistry and biology of deoxy-myo-inositol phosphates: stereospecificity of substrate interactions within an archaeal and a bacterial IMPase. Journal of the American Chemical Society. 126: 15370-1. PMID 15563150 DOI: 10.1021/Ja047360X  0.416
2004 Roberts MF, Redfield AG. High-resolution 31p field cycling NMR as a probe of phospholipid dynamics. Journal of the American Chemical Society. 126: 13765-77. PMID 15493936 DOI: 10.1021/Ja046658K  0.338
2004 Kobayashi M, Mutharasan RK, Feng J, Roberts MF, Lomasney JW. Identification of hydrophobic interactions between proteins and lipids: free fatty acids activate phospholipase C delta1 via allosterism. Biochemistry. 43: 7522-33. PMID 15182194 DOI: 10.1021/Bi035966C  0.407
2004 Zhang X, Wehbi H, Roberts MF. Cross-linking phosphatidylinositol-specific phospholipase C traps two activating phosphatidylcholine molecules on the enzyme. The Journal of Biological Chemistry. 279: 20490-500. PMID 14996830 DOI: 10.1074/Jbc.M401016200  0.806
2004 Feng J, Stieglitz K, Roberts MF. Mutation of two active-site residues converts a phosphatidylinositol-specific phospholipase C to a glucose phosphatase. Journal of the American Chemical Society. 126: 1008-9. PMID 14746454 DOI: 10.1021/Ja038529U  0.424
2003 Zambonelli C, Casali M, Roberts MF. Mutagenesis of putative catalytic and regulatory residues of Streptomyces chromofuscus phospholipase D differentially modifies phosphatase and phosphodiesterase activities. The Journal of Biological Chemistry. 278: 52282-9. PMID 14557260 DOI: 10.1074/Jbc.M310252200  0.447
2003 Yang H, Roberts MF. Phosphohydrolase and transphosphatidylation reactions of two Streptomyces phospholipase D enzymes: covalent versus noncovalent catalysis. Protein Science : a Publication of the Protein Society. 12: 2087-98. PMID 12931007 DOI: 10.1110/Ps.03192503  0.627
2003 Wehbi H, Feng J, Kolbeck J, Ananthanarayanan B, Cho W, Roberts MF. Investigating the interfacial binding of bacterial phosphatidylinositol-specific phospholipase C. Biochemistry. 42: 9374-82. PMID 12899624 DOI: 10.1021/Bi034195+  0.801
2003 Oh MK, Yang H, Roberts MF. Using O-(n-alkyl)-N-(N,N'-dimethylethyl)phosphoramidates to investigate the role of Ca2+ and interfacial binding in a bacterial phospholipase D. Biochimica Et Biophysica Acta. 1649: 146-53. PMID 12878033 DOI: 10.1016/S1570-9639(03)00166-3  0.617
2003 Wehbi H, Feng J, Roberts MF. Water-miscible organic cosolvents enhance phosphatidylinositol-specific phospholipase C phosphotransferase as well as phosphodiesterase activity. Biochimica Et Biophysica Acta. 1613: 15-27. PMID 12832083 DOI: 10.1016/S0005-2736(03)00134-2  0.808
2003 Feng J, Bradley WD, Roberts MF. Optimizing the interfacial binding and activity of a bacterial phosphatidylinositol-specific phospholipase C. The Journal of Biological Chemistry. 278: 24651-7. PMID 12714598 DOI: 10.1074/Jbc.M301207200  0.448
2003 Stieglitz KA, Seaton BA, Head JF, Stec B, Roberts MF. Unexpected similarity in regulation between an archaeal inositol monophosphatase/fructose bisphosphatase and chloroplast fructose bisphosphatase. Protein Science : a Publication of the Protein Society. 12: 760-7. PMID 12649434 DOI: 10.1110/Ps.0236003  0.381
2003 Zambonelli C, Roberts MF. An iron-dependent bacterial phospholipase D reminiscent of purple acid phosphatases. The Journal of Biological Chemistry. 278: 13706-11. PMID 12519726 DOI: 10.1074/Jbc.M210363200  0.348
2002 Yang H, Roberts MF. Cloning, overexpression, and characterization of a bacterial Ca2+-dependent phospholipase D. Protein Science : a Publication of the Protein Society. 11: 2958-68. PMID 12441393 DOI: 10.1110/Ps.0225302  0.63
2002 Stieglitz KA, Johnson KA, Yang H, Roberts MF, Seaton BA, Head JF, Stec B. Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop. The Journal of Biological Chemistry. 277: 22863-74. PMID 11940584 DOI: 10.1074/Jbc.M201042200  0.57
2002 Feng J, Wehbi H, Roberts MF. Role of tryptophan residues in interfacial binding of phosphatidylinositol-specific phospholipase C. The Journal of Biological Chemistry. 277: 19867-75. PMID 11912206 DOI: 10.1074/Jbc.M200938200  0.823
2002 Stec B, Stieglitz KA, Johnson KA, Yang H, Roberts MF. How myo-inositol is made in every living cell. The structures and insights into catalysis of inositol-1-phosphate synthase (IPS) and inositol-1-phosphate phosphatase (IMPase/FBPase) fromArchaeoglobus fulgidus Acta Crystallographica Section a Foundations of Crystallography. 58: c113-c113. DOI: 10.1107/S0108767302089535  0.595
2001 Stieglitz KA, Seaton BA, Roberts MF. Binding of proteolytically processed phospholipase D from Streptomyces chromofuscus to phosphatidylcholine membranes facilitates vesicle aggregation and fusion. Biochemistry. 40: 13954-63. PMID 11705386 DOI: 10.1021/Bi011338O  0.426
2001 Robinson P, Neelon K, Schreier HJ, Roberts MF. beta-Glutamate as a substrate for glutamine synthetase. Applied and Environmental Microbiology. 67: 4458-63. PMID 11571143 DOI: 10.1128/Aem.67.10.4458-4463.2001  0.762
2001 Johnson KA, Chen L, Yang H, Roberts MF, Stec B. Crystal structure and catalytic mechanism of the MJ0109 gene product: a bifunctional enzyme with inositol monophosphatase and fructose 1,6-bisphosphatase activities. Biochemistry. 40: 618-30. PMID 11170378 DOI: 10.1021/Bi0016422  0.796
2001 Martin DD, Ciulla RA, Robinson PM, Roberts MF. Switching osmolyte strategies: response of Methanococcus thermolithotrophicus to changes in external NaCl. Biochimica Et Biophysica Acta. 1524: 1-10. PMID 11078952 DOI: 10.1016/S0304-4165(00)00131-8  0.327
2000 Stec B, Yang H, Johnson KA, Chen L, Roberts MF. MJ0109 is an enzyme that is both an inositol monophosphatase and the 'missing' archaeal fructose-1,6-bisphosphatase. Nature Structural Biology. 7: 1046-50. PMID 11062561 DOI: 10.1038/80968  0.76
2000 Chen L, Zhou C, Yang H, Roberts MF. Inositol-1-phosphate synthase from Archaeoglobus fulgidus is a class II aldolase. Biochemistry. 39: 12415-23. PMID 11015222 DOI: 10.1021/Bi001517Q  0.796
2000 Chen L, Roberts MF. Overexpression, purification, and analysis of complementation behavior of E. coli SuhB protein: comparison with bacterial and archaeal inositol monophosphatases. Biochemistry. 39: 4145-53. PMID 10747806 DOI: 10.1021/Bi992424F  0.711
1999 Chen L, Roberts MF. Characterization of a tetrameric inositol monophosphatase from the hyperthermophilic bacterium Thermotoga maritima. Applied and Environmental Microbiology. 65: 4559-67. PMID 10508089 DOI: 10.1128/Aem.65.10.4559-4567.1999  0.749
1999 Geng D, Baker DP, Foley SF, Zhou C, Stieglitz K, Roberts MF. A 20-kDa domain is required for phosphatidic acid-induced allosteric activation of phospholipase D from Streptomyces chromofuscus. Biochimica Et Biophysica Acta. 1430: 234-44. PMID 10082951 DOI: 10.1016/S0167-4838(99)00005-9  0.425
1999 Zhou C, Horstman D, Carpenter G, Roberts MF. Action of phosphatidylinositol-specific phospholipase Cgamma1 on soluble and micellar substrates. Separating effects on catalysis from modulation of the surface. The Journal of Biological Chemistry. 274: 2786-93. PMID 9915811 DOI: 10.1074/Jbc.274.5.2786  0.318
1998 Zhou C, Roberts MF. Nonessential activation and competitive inhibition of bacterial phosphatidylinositol-specific phospholipase C by short-chain phospholipids and analogues. Biochemistry. 37: 16430-9. PMID 9819236 DOI: 10.1021/Bi980601R  0.468
1998 Chen L, Spiliotis ET, Roberts MF. Biosynthesis of Di-myo-inositol-1,1'-phosphate, a novel osmolyte in hyperthermophilic archaea. Journal of Bacteriology. 180: 3785-92. PMID 9683472 DOI: 10.1128/Jb.180.15.3785-3792.1998  0.735
1998 Chen L, Roberts MF. Cloning and expression of the inositol monophosphatase gene from Methanococcus jannaschii and characterization of the enzyme. Applied and Environmental Microbiology. 64: 2609-15. PMID 9647837 DOI: 10.1128/Aem.64.7.2609-2615.1998  0.748
1998 Geng D, Chura J, Roberts MF. Activation of phospholipase D by phosphatidic acid. Enhanced vesicle binding, phosphatidic acid-Ca2+ interaction, or an allosteric effect? The Journal of Biological Chemistry. 273: 12195-202. PMID 9575167 DOI: 10.1074/Jbc.273.20.12195  0.412
1998 Qian X, Zhou C, Roberts MF. Phosphatidylcholine activation of bacterial phosphatidylinositol-specific phospholipase C toward PI vesicles. Biochemistry. 37: 6513-22. PMID 9572869 DOI: 10.1021/Bi972650U  0.399
1998 Tan CA, Roberts MF. Engineering of the nonspecific phospholipase C from Bacillus cereus: replacement of glutamic acid-4 by alanine results in loss of interfacial catalysis and enhanced phosphomonoesterase activity. Biochemistry. 37: 4275-9. PMID 9521750 DOI: 10.1021/Bi972751S  0.455
1997 Zhou C, Garigapati V, Roberts MF. Short-chain phosphatidylinositol conformation and its relevance to phosphatidylinositol-specific phospholipase C. Biochemistry. 36: 15925-31. PMID 9398326 DOI: 10.1021/Bi9716175  0.349
1997 Zhou C, Roberts MF. Diacylglycerol partitioning and mixing in detergent micelles: relevance to enzyme kinetics. Biochimica Et Biophysica Acta. 1348: 273-86. PMID 9366244 DOI: 10.1016/S0005-2760(97)00066-0  0.396
1997 Wu Y, Perisic O, Williams RL, Katan M, Roberts MF. Phosphoinositide-specific phospholipase C delta1 activity toward micellar substrates, inositol 1,2-cyclic phosphate, and other water-soluble substrates: a sequential mechanism and allosteric activation. Biochemistry. 36: 11223-33. PMID 9287165 DOI: 10.1021/Bi971039S  0.754
1997 Tan CA, Hehir MJ, Roberts MF. Cloning, overexpression, refolding, and purification of the nonspecific phospholipase C from Bacillus cereus. Protein Expression and Purification. 10: 365-72. PMID 9268684 DOI: 10.1006/Prep.1997.0756  0.382
1997 Zhou C, Qian X, Roberts MF. Allosteric activation of phosphatidylinositol-specific phospholipase C: specific phospholipid binding anchors the enzyme to the interface. Biochemistry. 36: 10089-97. PMID 9254604 DOI: 10.1021/Bi970846O  0.481
1997 Wu Y, Roberts MF. Phosphatidylinositol-specific phospholipase C cyclic phosphodiesterase activity depends on solvent polarity. Biochemistry. 36: 8514-21. PMID 9214296 DOI: 10.1021/Bi970560J  0.735
1997 Essen LO, Perisic O, Katan M, Wu Y, Roberts MF, Williams RL. Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C. Biochemistry. 36: 1704-18. PMID 9048554 DOI: 10.1021/Bi962512P  0.731
1997 Wu Y, Zhou C, Roberts MF. Stereocontrolled syntheses of water-soluble inhibitors of phosphatidylinositol-specific phospholipase C: inhibition enhanced by an interface. Biochemistry. 36: 356-63. PMID 9003188 DOI: 10.1021/Bi960602O  0.729
1997 Zhou C, Wu Y, Roberts MF. Activation of phosphatidylinositol-specific phospholipase C toward inositol 1,2-(cyclic)-phosphate. Biochemistry. 36: 347-55. PMID 9003187 DOI: 10.1021/Bi960601W  0.765
1997 Hou C, Ohm X, Roberts MF. AI.I.osteric activation of phosphatidylinositoi.specific phospholipasb C: Specific phospholipid binding anchors the enzyme to the interface Faseb Journal. 11: A1027.  0.322
1996 Tan CA, Roberts MF. Vanadate is a potent competitive inhibitor of phospholipase C from Bacillus cereus. Biochimica Et Biophysica Acta. 1298: 58-68. PMID 8948489 DOI: 10.1016/S0167-4838(96)00114-8  0.411
1996 Roberts MF, Wu Y, Zhou C, Geng D, Tan C. Mechanism and structure based inhibitors of phospholipase C enzymes. Advances in Enzyme Regulation. 36: 57-71. PMID 8869740 DOI: 10.1016/0065-2571(95)00017-8  0.74
1996 Roberts MF. Phospholipases: structural and functional motifs for working at an interface. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 1159-72. PMID 8751718 DOI: 10.1096/Fasebj.10.10.8751718  0.403
1996 Friedman P, Haimovitz R, Markman O, Roberts MF, Shinitzky M. Conversion of lysophospholipids to cyclic lysophosphatidic acid by phospholipase D. The Journal of Biological Chemistry. 271: 953-7. PMID 8557710 DOI: 10.1074/Jbc.271.2.953  0.364
1996 Markman O, Roh C, Roberts MF, Teeter MM. Designed additives for controlled growth of crystals of phospholipid interacting proteins: Short chain phospholipids Journal of Crystal Growth. 160: 382-388. DOI: 10.1016/0022-0248(95)00745-8  0.308
1995 Ciulla R, Krishnan S, Roberts MF. Internalization of Sucrose by Methanococcus thermolithotrophicus. Applied and Environmental Microbiology. 61: 421-9. PMID 16534924 DOI: 10.1128/Aem.61.2.421-429.1995  0.3
1995 Maloney KM, Grandbois M, Grainger DW, Salesse C, Lewis KA, Roberts MF. Phospholipase A2 domain formation in hydrolyzed asymmetric phospholipid monolayers at the air/water interface. Biochimica Et Biophysica Acta. 1235: 395-405. PMID 7756350 DOI: 10.1016/0005-2736(95)80029-F  0.336
1995 Garigapati VR, Bian J, Roberts MF. Synthesis and Characterization of Short-Chain Diacylphosphatidic Acids Journal of Colloid and Interface Science. 169: 486-492. DOI: 10.1006/Jcis.1995.1059  0.326
1994 Ciulla RA, Burggraf S, Stetter KO, Roberts MF. Occurrence and Role of Di-myo-Inositol-1,1'-Phosphate in Methanococcus igneus. Applied and Environmental Microbiology. 60: 3660-4. PMID 16349412 DOI: 10.1128/Aem.60.10.3660-3664.1994  0.312
1994 Gorkovenko A, Roberts MF, White RH. Identification, Biosynthesis, and Function of 1,3,4,6-Hexanetetracarboxylic Acid in Methanobacterium thermoautotrophicum DeltaH. Applied and Environmental Microbiology. 60: 1249-53. PMID 16349232 DOI: 10.1128/Aem.60.4.1249-1253.1994  0.32
1994 Lewis KA, Soltys CE, Yu K, Roberts MF. Micellar bolaform and omega-carboxylate phosphatidylcholines as substrates for phospholipases. Biochemistry. 33: 5000-10. PMID 8172875 DOI: 10.1021/Bi00183A002  0.368
1994 Swairjo MA, Roberts MF, Campos MB, Dedman JR, Seaton BA. Annexin V binding to the outer leaflet of small unilamellar vesicles leads to altered inner-leaflet properties: 31P- and 1H-NMR studies. Biochemistry. 33: 10944-50. PMID 8086411 DOI: 10.1021/Bi00202A013  0.352
1994 Soltys CE, Roberts MF. Fluorescence studies of phosphatidylcholine micelle mixing: relevance to phospholipase kinetics. Biochemistry. 33: 11608-17. PMID 7918374 DOI: 10.1021/Bi00204A023  0.307
1993 Lewis KA, Garigapati VR, Zhou C, Roberts MF. Substrate requirements of bacterial phosphatidylinositol-specific phospholipase C. Biochemistry. 32: 8836-41. PMID 8395883 DOI: 10.1021/Bi00085A014  0.441
1993 Soltys CE, Bian J, Roberts MF. Polymerizable phosphatidylcholines: importance of phospholipid motions for optimum phospholipase A2 and C activity. Biochemistry. 32: 9545-52. PMID 8373761 DOI: 10.1021/Bi00088A005  0.41
1993 Gorkovenko A, Roberts MF. Cyclic 2,3-diphosphoglycerate as a component of a new branch in gluconeogenesis in Methanobacterium thermoautotrophicum delta H. Journal of Bacteriology. 175: 4087-95. PMID 8320225 DOI: 10.1128/Jb.175.13.4087-4095.1993  0.312
1993 Nochur SV, Roberts MF, Demain AL. True cellulase production by Clostridium thermocellum grown on different carbon sources Biotechnology Letters. 15: 641-646. DOI: 10.1007/Bf00138556  0.301
1992 Robertson DE, Lai MC, Gunsalus RP, Roberts MF. Composition, Variation, and Dynamics of Major Osmotic Solutes in Methanohalophilus Strain FDF1. Applied and Environmental Microbiology. 58: 2438-43. PMID 16348748 DOI: 10.1128/Aem.58.8.2438-2443.1992  0.313
1992 Sastry MV, Robertson DE, Moynihan JA, Roberts MF. Enzymatic degradation of cyclic 2,3-diphosphoglycerate to 2,3-diphosphoglycerate in Methanobacterium thermoautotrophicum. Biochemistry. 31: 2926-35. PMID 1550819 DOI: 10.1021/Bi00126A012  0.381
1992 Evans JN, Arvidson DN, Gunsalus RP, Roberts MF. Multinuclear NMR studies of the trp-repressor. Biochimica Et Biophysica Acta. 1160: 156-62. PMID 1445942 DOI: 10.1016/0167-4838(92)90002-U  0.312
1992 Stebbins JW, Robertson DE, Roberts MF, Stevens RC, Lipscomb WN, Kantrowitz ER. Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study. Protein Science : a Publication of the Protein Society. 1: 1435-46. PMID 1303763 DOI: 10.1002/Pro.5560011105  0.65
1992 Nochur SV, Jacobson GR, Roberts MF, Demain AL. Mode of sugar phosphorylation in Clostridium thermocellum Applied Biochemistry and Biotechnology. 33: 33-41. DOI: 10.1007/Bf02922182  0.303
1991 Roberts MF. Nuclear magnetic resonance spectroscopy to follow phospholipase kinetics and products. Methods in Enzymology. 197: 31-48. PMID 2051926 DOI: 10.1016/0076-6879(91)97131-H  0.372
1991 Roberts MF. Assays of phospholipases on short-chain phospholipids. Methods in Enzymology. 197: 95-112. PMID 1904976 DOI: 10.1016/0076-6879(91)97137-N  0.37
1990 Lewis KA, Bian JR, Sweeney A, Roberts MF. Asymmetric short-chain phosphatidylcholines: defining chain binding constraints in phospholipases. Biochemistry. 29: 9962-70. PMID 2271632 DOI: 10.1021/Bi00494A029  0.359
1985 DeBose CD, Burns RA, Donovan JM, Roberts MF. Methyl branching in short-chain lecithins: are both chains important for effective phospholipase A2 activity? Biochemistry. 24: 1298-306. PMID 3986178 DOI: 10.1021/Bi00327A005  0.397
1982 Burns RA, Roberts MF. Cholesterol solubilization by short-chain lecithins: characterization of mixed micelles and cholesterol oxidase activity. Biochemistry. 20: 7102-8. PMID 6947824 DOI: 10.1021/Bi00528A008  0.319
1982 Burns RA, El-Sayed MY, Roberts MF. Kinetic model for surface-active enzymes based on the Langmuir adsorption isotherm: phospholipase C (Bacillus cereus) activity toward dimyristoyl phosphatidylcholine/detergent micelles. Proceedings of the National Academy of Sciences of the United States of America. 79: 4902-6. PMID 6812057 DOI: 10.1073/Pnas.79.16.4902  0.414
1979 Adamich M, Roberts MF, Dennis EA. Phospholipid activation of cobra venom phospholipase A2. 2. Characterization of the phospholipid--enzyme interaction. Biochemistry. 18: 3308-14. PMID 465469 DOI: 10.1021/Bi00582A017  0.549
1979 Roberts MF, Adamich M, Robson RJ, Dennis EA. Phospholipid activation of cobra venom phospholipase A2. 1. Lipid--lipid or lipid--enzyme interaction. Biochemistry. 18: 3301-8. PMID 465468 DOI: 10.1021/Bi00582A016  0.519
1978 Shaw JO, Roberts MF, Ulevitch RJ, Henson P, Dennis EA. Phospholipase A2 contamination of cobra venom factor preparations. Biologic role in complement-dependent in vivo reactions and inactivation with p-bromophenacyl bromide. The American Journal of Pathology. 91: 517-30. PMID 655262  0.44
1978 Roberts MF, Otnaess AB, Kensil CA, Dennis EA. The specificity of phospholipase A2 and phospholipase C in a mixed micellar system. The Journal of Biological Chemistry. 253: 1252-7. PMID 624729  0.398
1978 Roberts MF, Bothner-By AA, Dennis EA. Magnetic nonequivalence within fatty acyl chains of phospholipids in membrane models: 1H nuclear magnetic resonance studies of the alpha-methylene groups. Biochemistry. 17: 935-42. PMID 580222 DOI: 10.1021/Bi00598A030  0.458
1978 Roberts MF, Switzer RL. Inactivation of Salmonella phosphoribosylpyrophosphate synthetase by specific chemical modification of a lysine residue Archives of Biochemistry and Biophysics. 185: 391-399. PMID 204252 DOI: 10.1016/0003-9861(78)90181-9  0.323
1977 Lewis RV, Roberts MF, Dennis EA, Allison WS. Photoactivated heterobifunctional cross-linking reagents which demonstrate the aggregation state of phospholipase A2. Biochemistry. 16: 5650-4. PMID 921957 DOI: 10.1021/Bi00644A041  0.532
1977 Roberts MF, Dennis EA. Proton nuclear magnetic resonance demonstration of conformationally nonequivalent phospholipid fatty acid chains in mixed micelles. Journal of the American Chemical Society. 99: 6142-3. PMID 893884 DOI: 10.1002/Chin.197749062  0.463
1977 Roberts MF, Deems RA, Dennis EA. Dual role of interfacial phospholipid in phospholipase A2 catalysis. Proceedings of the National Academy of Sciences of the United States of America. 74: 1950-4. PMID 266715 DOI: 10.1073/Pnas.74.5.1950  0.569
1977 Roberts MF, Deems RA, Dennis EA. Spectral perturbations of the histidine and tryptophan in cobra venom phospholipase A2 upon metal ion and mixed micelle binding. The Journal of Biological Chemistry. 252: 6011-7. PMID 19461  0.404
1977 Roberts MF, Deems RA, Mincey TC, Dennis EA. Chemical modification of the histidine residue in phospholipase A2 (Naja naja naja). A case of half-site reactivity. The Journal of Biological Chemistry. 252: 2405-11. PMID 14964  0.554
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