Gary Coombs - Publications

Affiliations: 
1993-1998 Biochemistry Waldorf College 

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Zhang X, Hagen J, Muniz VP, Smith T, Coombs GS, Eischen CM, Mackie DI, Roman DL, Van Rheeden R, Darbro B, Tompkins VS, Quelle DE. RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts. Plos One. 8: e80228. PMID 24282525 DOI: 10.1371/journal.pone.0080228  0.44
2010 Covey TM, Edes K, Coombs GS, Virshup DM, Fitzpatrick FA. Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer. Plos One. 5: e13545. PMID 20975834 DOI: 10.1371/journal.pone.0013545  0.44
2010 Coombs GS, Yu J, Canning CA, Veltri CA, Covey TM, Cheong JK, Utomo V, Banerjee N, Zhang ZH, Jadulco RC, Concepcion GP, Bugni TS, Harper MK, Mihalek I, Jones CM, et al. WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification. Journal of Cell Science. 123: 3357-67. PMID 20826466 DOI: 10.1242/jcs.072132  0.44
2009 McCulloch MW, Bugni TS, Concepcion GP, Coombs GS, Harper MK, Kaur S, Mangalindan GC, Mutizwa MM, Veltri CA, Virshup DM, Ireland CM. Carteriosulfonic acids A-C, GSK-3beta inhibitors from a Carteriospongia sp. Journal of Natural Products. 72: 1651-6. PMID 19778090 DOI: 10.1021/np900336f  0.44
2009 McCulloch MW, Coombs GS, Banerjee N, Bugni TS, Cannon KM, Harper MK, Veltri CA, Virshup DM, Ireland CM. Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives. Bioorganic & Medicinal Chemistry. 17: 2189-98. PMID 19022675 DOI: 10.1016/j.bmc.2008.10.077  0.44
2008 Coombs GS, Covey TM, Virshup DM. Wnt signaling in development, disease and translational medicine. Current Drug Targets. 9: 513-31. PMID 18673238 DOI: 10.2174/138945008784911796  0.44
2007 Luo W, Peterson A, Garcia BA, Coombs G, Kofahl B, Heinrich R, Shabanowitz J, Hunt DF, Yost HJ, Virshup DM. Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. The Embo Journal. 26: 1511-21. PMID 17318175 DOI: 10.1038/sj.emboj.7601607  0.44
2006 Swiatek W, Kang H, Garcia BA, Shabanowitz J, Coombs GS, Hunt DF, Virshup DM. Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation. The Journal of Biological Chemistry. 281: 12233-41. PMID 16513652 DOI: 10.1074/jbc.M510580200  0.44
2003 Bergstrom RC, Coombs GS, Ye S, Madison EL, Goldsmith EJ, Corey DR. Binding of nonphysiological protein and peptide substrates to proteases: differences between urokinase-type plasminogen activator and trypsin and contributions to the evolution of regulated proteolysis. Biochemistry. 42: 5395-402. PMID 12731881 DOI: 10.1021/bi027417x  0.44
2003 Zeslawska E, Jacob U, Schweinitz A, Coombs G, Bode W, Madison E. Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors. Journal of Molecular Biology. 328: 109-18. PMID 12684001 DOI: 10.1016/S0022-2836(03)00267-5  0.44
2002 Friedrich R, Fuentes-Prior P, Ong E, Coombs G, Hunter M, Oehler R, Pierson D, Gonzalez R, Huber R, Bode W, Madison EL. Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase. The Journal of Biological Chemistry. 277: 2160-8. PMID 11696548 DOI: 10.1074/jbc.M109830200  0.44
2000 Hervio LS, Coombs GS, Bergstrom RC, Trivedi K, Corey DR, Madison EL. Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates. Chemistry & Biology. 7: 443-53. PMID 10873836 DOI: 10.1016/S1074-5521(00)00125-3  0.44
1998 Coombs GS, Bergstrom RC, Pellequer JL, Baker SI, Navre M, Smith MM, Tainer JA, Madison EL, Corey DR. Substrate specificity of prostate-specific antigen (PSA). Chemistry & Biology. 5: 475-88. PMID 9751643  0.44
1998 Coombs GS, Bergstrom RC, Madison EL, Corey DR. Directing sequence-specific proteolysis to new targets. The influence of loop size and target sequence on selective proteolysis by tissue-type plasminogen activator and urokinase-type plasminogen activator. The Journal of Biological Chemistry. 273: 4323-8. PMID 9468480 DOI: 10.1074/jbc.273.8.4323  0.44
1997 Ke SH, Coombs GS, Tachias K, Corey DR, Madison EL. Optimal subsite occupancy and design of a selective inhibitor of urokinase. The Journal of Biological Chemistry. 272: 20456-62. PMID 9252355 DOI: 10.1074/jbc.272.33.20456  0.44
1997 Ke SH, Coombs GS, Tachias K, Navre M, Corey DR, Madison EL. Distinguishing the specificities of closely related proteases. Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase. The Journal of Biological Chemistry. 272: 16603-9. PMID 9195973 DOI: 10.1074/jbc.272.26.16603  0.44
1996 Coombs GS, Dang AT, Madison EL, Corey DR. Distinct mechanisms contribute to stringent substrate specificity of tissue-type plasminogen activator. The Journal of Biological Chemistry. 271: 4461-7. PMID 8626799 DOI: 10.1074/jbc.271.8.4461  0.44
1995 Madison EL, Coombs GS, Corey DR. Substrate specificity of tissue type plasminogen activator. Characterization of the fibrin independent specificity of t-PA for plasminogen. The Journal of Biological Chemistry. 270: 7558-62. PMID 7706303  0.44
1995 Ding L, Coombs GS, Strandberg L, Navre M, Corey DR, Madison EL. Origins of the specificity of tissue-type plasminogen activator. Proceedings of the National Academy of Sciences of the United States of America. 92: 7627-31. PMID 7644467 DOI: 10.1073/pnas.92.17.7627  0.44
1995 Corey DR, Willett WS, Coombs GS, Craik CS. Trypsin specificity increased through substrate-assisted catalysis. Biochemistry. 34: 11521-7. PMID 7547882  0.44
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