| Year |
Citation |
Score |
| 2003 |
Bergstrom RC, Coombs GS, Ye S, Madison EL, Goldsmith EJ, Corey DR. Binding of nonphysiological protein and peptide substrates to proteases: differences between urokinase-type plasminogen activator and trypsin and contributions to the evolution of regulated proteolysis. Biochemistry. 42: 5395-402. PMID 12731881 DOI: 10.1021/Bi027417X |
0.642 |
|
| 2003 |
Zeslawska E, Jacob U, Schweinitz A, Coombs G, Bode W, Madison E. Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors. Journal of Molecular Biology. 328: 109-18. PMID 12684001 DOI: 10.1016/S0022-2836(03)00267-5 |
0.432 |
|
| 2002 |
Friedrich R, Fuentes-Prior P, Ong E, Coombs G, Hunter M, Oehler R, Pierson D, Gonzalez R, Huber R, Bode W, Madison EL. Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase. The Journal of Biological Chemistry. 277: 2160-8. PMID 11696548 DOI: 10.1074/Jbc.M109830200 |
0.384 |
|
| 2000 |
Hervio LS, Coombs GS, Bergstrom RC, Trivedi K, Corey DR, Madison EL. Negative selectivity and the evolution of protease cascades: the specificity of plasmin for peptide and protein substrates. Chemistry & Biology. 7: 443-53. PMID 10873836 DOI: 10.1016/S1074-5521(00)00125-3 |
0.579 |
|
| 1999 |
Coombs GS, Rao MS, Olson AJ, Dawson PE, Madison EL. Revisiting catalysis by chymotrypsin family serine proteases using peptide substrates and inhibitors with unnatural main chains. The Journal of Biological Chemistry. 274: 24074-9. PMID 10446178 DOI: 10.1074/Jbc.274.34.24074 |
0.387 |
|
| 1998 |
Coombs GS, Bergstrom RC, Pellequer JL, Baker SI, Navre M, Smith MM, Tainer JA, Madison EL, Corey DR. Substrate specificity of prostate-specific antigen (PSA). Chemistry & Biology. 5: 475-88. PMID 9751643 DOI: 10.1016/S1074-5521(98)90004-7 |
0.489 |
|
| 1998 |
Coombs GS, Bergstrom RC, Madison EL, Corey DR. Directing sequence-specific proteolysis to new targets. The influence of loop size and target sequence on selective proteolysis by tissue-type plasminogen activator and urokinase-type plasminogen activator. The Journal of Biological Chemistry. 273: 4323-8. PMID 9468480 DOI: 10.1074/Jbc.273.8.4323 |
0.626 |
|
| 1997 |
Ke SH, Coombs GS, Tachias K, Corey DR, Madison EL. Optimal subsite occupancy and design of a selective inhibitor of urokinase. The Journal of Biological Chemistry. 272: 20456-62. PMID 9252355 DOI: 10.1074/Jbc.272.33.20456 |
0.661 |
|
| 1997 |
Ke SH, Coombs GS, Tachias K, Navre M, Corey DR, Madison EL. Distinguishing the specificities of closely related proteases. Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase. The Journal of Biological Chemistry. 272: 16603-9. PMID 9195973 DOI: 10.1074/Jbc.272.26.16603 |
0.645 |
|
| 1997 |
Corey DR, Coombs GS, Bergstrom RC, Madison EL. 178 Targeting proteolysis to non-physiological protein substrates Fibrinolysis and Proteolysis. 11: 51. DOI: 10.1016/S0268-9499(97)80293-7 |
0.505 |
|
| 1996 |
Coombs GS, Dang AT, Madison EL, Corey DR. Distinct mechanisms contribute to stringent substrate specificity of tissue-type plasminogen activator. The Journal of Biological Chemistry. 271: 4461-7. PMID 8626799 DOI: 10.1074/Jbc.271.8.4461 |
0.676 |
|
| 1995 |
Madison EL, Coombs GS, Corey DR. Substrate specificity of tissue type plasminogen activator. Characterization of the fibrin independent specificity of t-PA for plasminogen. The Journal of Biological Chemistry. 270: 7558-62. PMID 7706303 DOI: 10.1074/Jbc.270.13.7558 |
0.634 |
|
| 1995 |
Ding L, Coombs GS, Strandberg L, Navre M, Corey DR, Madison EL. Origins of the specificity of tissue-type plasminogen activator. Proceedings of the National Academy of Sciences of the United States of America. 92: 7627-31. PMID 7644467 DOI: 10.1073/Pnas.92.17.7627 |
0.655 |
|
| 1995 |
Corey DR, Willett WS, Coombs GS, Craik CS. Trypsin specificity increased through substrate-assisted catalysis. Biochemistry. 34: 11521-7. PMID 7547882 DOI: 10.1021/Bi00036A027 |
0.643 |
|
| 1995 |
Coombs GS, Hazzard J, Corey DR. Kinetic characterization of a peptide inhibitor of trypsin isolated from a synthetic peptide combinatorial library Bioorganic and Medicinal Chemistry Letters. 5: 611-614. DOI: 10.1016/0960-894X(95)00082-5 |
0.564 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1995 |
Foreman DT, Martinez Y, Coombs G, Torres A, Kupersztoch YM. TolC and DsbA are needed for the secretion of STB, a heat-stable enterotoxin of Escherichia coli. Molecular Microbiology. 18: 237-45. PMID 8709843 DOI: 10.1111/J.1365-2958.1995.Mmi_18020237.X |
0.269 |
|
| 2007 |
Luo W, Peterson A, Garcia BA, Coombs G, Kofahl B, Heinrich R, Shabanowitz J, Hunt DF, Yost HJ, Virshup DM. Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. The Embo Journal. 26: 1511-21. PMID 17318175 DOI: 10.1038/Sj.Emboj.7601607 |
0.248 |
|
| 2013 |
Zhang X, Hagen J, Muniz VP, Smith T, Coombs GS, Eischen CM, Mackie DI, Roman DL, Van Rheeden R, Darbro B, Tompkins VS, Quelle DE. RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts. Plos One. 8: e80228. PMID 24282525 DOI: 10.1371/Journal.Pone.0080228 |
0.217 |
|
| 2010 |
Coombs GS, Yu J, Canning CA, Veltri CA, Covey TM, Cheong JK, Utomo V, Banerjee N, Zhang ZH, Jadulco RC, Concepcion GP, Bugni TS, Harper MK, Mihalek I, Jones CM, et al. WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification. Journal of Cell Science. 123: 3357-67. PMID 20826466 DOI: 10.1242/Jcs.072132 |
0.187 |
|
| 2009 |
McCulloch MW, Coombs GS, Banerjee N, Bugni TS, Cannon KM, Harper MK, Veltri CA, Virshup DM, Ireland CM. Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives. Bioorganic & Medicinal Chemistry. 17: 2189-98. PMID 19022675 DOI: 10.1016/J.Bmc.2008.10.077 |
0.166 |
|
| 2006 |
Swiatek W, Kang H, Garcia BA, Shabanowitz J, Coombs GS, Hunt DF, Virshup DM. Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation. The Journal of Biological Chemistry. 281: 12233-41. PMID 16513652 DOI: 10.1074/Jbc.M510580200 |
0.136 |
|
| 2021 |
Coombs GS, Rios-Monterrosa JL, Lai S, Dai Q, Goll AC, Ketterer MR, Valdes MF, Uche N, Benjamin IJ, Wallrath LL. Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins. Redox Biology. 48: 102196. PMID 34872044 DOI: 10.1016/j.redox.2021.102196 |
0.13 |
|
| 2009 |
McCulloch MW, Bugni TS, Concepcion GP, Coombs GS, Harper MK, Kaur S, Mangalindan GC, Mutizwa MM, Veltri CA, Virshup DM, Ireland CM. Carteriosulfonic acids A-C, GSK-3beta inhibitors from a Carteriospongia sp. Journal of Natural Products. 72: 1651-6. PMID 19778090 DOI: 10.1021/Np900336F |
0.097 |
|
| 2008 |
Coombs GS, Covey TM, Virshup DM. Wnt signaling in development, disease and translational medicine. Current Drug Targets. 9: 513-31. PMID 18673238 DOI: 10.2174/138945008784911796 |
0.086 |
|
| 2010 |
Covey TM, Edes K, Coombs GS, Virshup DM, Fitzpatrick FA. Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer. Plos One. 5: e13545. PMID 20975834 DOI: 10.1371/Journal.Pone.0013545 |
0.079 |
|
| 2022 |
Shaw NM, Rios-Monterrosa JL, Fedorchak GR, Ketterer MR, Coombs GS, Lammerding J, Wallrath LL. Effects of mutant lamins on nucleo-cytoskeletal coupling in models of muscular dystrophy. Frontiers in Cell and Developmental Biology. 10: 934586. PMID 36120560 DOI: 10.3389/fcell.2022.934586 |
0.061 |
|
| Hide low-probability matches. |