John T. Koh - Publications

Affiliations: 
University of Delaware, Newark, DE, United States 
Area:
Bioorganic Chemistry, Organic Chemistry, Chemical Biology

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhang Y, Mantravadi PK, Jobbagy S, Bao W, Koh JT. Antagonizing the Androgen Receptor with a Biomimetic Acyltransferase. Acs Chemical Biology. PMID 27548116 DOI: 10.1021/Acschembio.6B00659  0.768
2016 Cadieux CL, Wang H, Zhang Y, Koenig JA, Shih TM, McDonough J, Koh J, Cerasoli D. Probing the Activity of a Non-Oxime Reactivator for Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents. Chemico-Biological Interactions. PMID 27062893 DOI: 10.1016/J.Cbi.2016.04.002  0.736
2012 Ceo LM, Koh JT. Photocaged DNA provides new levels of transcription control. Chembiochem : a European Journal of Chemical Biology. 13: 511-3. PMID 22271631 DOI: 10.1002/Cbic.201100683  0.751
2010 Jain D, Koh JT. A mutant selective anti-estrogen is a pure antagonist on EREs and AP-1 response elements. Bioorganic & Medicinal Chemistry Letters. 20: 5258-61. PMID 20659801 DOI: 10.1016/J.Bmcl.2010.06.151  0.77
2010 Sauers DJ, Temburni MK, Biggins JB, Ceo LM, Galileo DS, Koh JT. Light-activated gene expression directs segregation of co-cultured cells in vitro. Acs Chemical Biology. 5: 313-20. PMID 20050613 DOI: 10.1021/Cb9002305  0.642
2008 Hassan AQ, Koh JT. Selective chemical rescue of a thyroid-hormone-receptor mutant, TRbeta(H435Y), identified in pituitary carcinoma and resistance to thyroid hormone. Angewandte Chemie (International Ed. in English). 47: 7280-3. PMID 18683837 DOI: 10.1002/Anie.200801742  0.329
2008 Zheng J, Hashimoto A, Putnam M, Miller K, Koh JT. Development of a thyroid hormone receptor targeting conjugate. Bioconjugate Chemistry. 19: 1227-34. PMID 18507428 DOI: 10.1021/Bc8000326  0.788
2007 Koh JT, Zheng J. The new biomimetic chemistry: artificial transcription factors. Acs Chemical Biology. 2: 599-601. PMID 17894442 DOI: 10.1021/Cb700183S  0.75
2007 Biggins JB, Hashimoto A, Koh JT. Photocaged agonist for an analogue-specific form of the vitamin D receptor. Chembiochem : a European Journal of Chemical Biology. 8: 799-803. PMID 17393546 DOI: 10.1002/Cbic.200600497  0.741
2007 Posner GH, Suh BC, Petersen KS, Dolan P, Agoston ES, Kensler TW, Koh JT, Peleg S. Difluoromethyl analogs of the natural hormone 1α,25-dihydroxyvitamin D3: Design, synthesis, and preliminary biological evaluation Journal of Steroid Biochemistry and Molecular Biology. 103: 213-221. PMID 17218093 DOI: 10.1016/J.Jsbmb.2006.12.024  0.326
2007 Biggins JB, Koh JT. Chemical biology of steroid and nuclear hormone receptors. Current Opinion in Chemical Biology. 11: 99-110. PMID 17188557 DOI: 10.1016/J.Cbpa.2006.10.042  0.721
2006 Fotos JS, Patel VP, Karin NJ, Temburni MK, Koh JT, Galileo DS. Automated time-lapse microscopy and high-resolution tracking of cell migration. Cytotechnology. 51: 7-19. PMID 19002890 DOI: 10.1007/S10616-006-9006-7  0.764
2006 Hassan AQ, Koh JT. A functionally orthogonal ligand-receptor pair created by targeting the allosteric mechanism of the thyroid hormone receptor. Journal of the American Chemical Society. 128: 8868-74. PMID 16819881 DOI: 10.1021/ja060760v  0.332
2005 Link KH, Shi Y, Koh JT. Light activated recombination. Journal of the American Chemical Society. 127: 13088-9. PMID 16173704 DOI: 10.1021/Ja0531226  0.789
2005 Koh JT, Biggins JB. Ligand-receptor engineering and its application towards the complementation of genetic disease and target identification. Current Topics in Medicinal Chemistry. 5: 413-20. PMID 15892683 DOI: 10.2174/1568026053828420  0.678
2005 Hashimoto A, Shi Y, Drake K, Koh JT. Design and synthesis of complementing ligands for mutant thyroid hormone receptor TRbeta(R320H): a tailor-made approach toward the treatment of resistance to thyroid hormone. Bioorganic & Medicinal Chemistry. 13: 3627-39. PMID 15862991 DOI: 10.1016/J.Bmc.2005.03.040  0.617
2005 Shi Y, Ye H, Link KH, Putnam MC, Hubner I, Dowdell S, Koh JT. Mutant-selective thyromimetics for the chemical rescue of thyroid hormone receptor mutants associated with resistance to thyroid hormone. Biochemistry. 44: 4612-26. PMID 15779888 DOI: 10.1021/Bi0482349  0.758
2005 Koh J. Spatial control of protein synthesis Chemistry and Biology. 12: 613-614. DOI: 10.1016/J.Chembiol.2005.06.006  0.305
2004 Link KH, Cruz FG, Ye HF, O'reilly KE, Dowdell S, Koh JT. Photo-caged agonists of the nuclear receptors RARgamma and TRbeta provide unique time-dependent gene expression profiles for light-activated gene patterning. Bioorganic & Medicinal Chemistry. 12: 5949-59. PMID 15498671 DOI: 10.1016/J.Bmc.2004.08.022  0.799
2004 Shi Y, Koh JT. Light-activated transcription and repression by using photocaged SERMs. Chembiochem : a European Journal of Chemical Biology. 5: 788-96. PMID 15174161 DOI: 10.1002/Cbic.200300823  0.661
2002 Swann SL, Bergh JJ, Farach-Carson MC, Koh JT. Rational design of vitamin D3 analogues which selectively restore activity to a vitamin D receptor mutant associated with rickets. Organic Letters. 4: 3863-6. PMID 12599478 DOI: 10.1021/ol0266931  0.746
2002 Swann SL, Bergh J, Farach-Carson MC, Ocasio CA, Koh JT. Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor. Journal of the American Chemical Society. 124: 13795-805. PMID 12431109 DOI: 10.1021/Ja0268377  0.775
2002 Shi Y, Koh JT. Functionally orthogonal ligand-receptor pairs for the selective regulation of gene expression generated by manipulation of charged residues at the ligand-receptor interface of ER alpha and ER beta. Journal of the American Chemical Society. 124: 6921-8. PMID 12059215 DOI: 10.1021/Ja016897X  0.572
2002 Koh JT. Engineering selectivity and discrimination into ligand-receptor interfaces. Chemistry & Biology. 9: 17-23. PMID 11841935 DOI: 10.1016/S1074-5521(02)00087-X  0.374
2001 Ye HF, O'Reilly KE, Koh JT. A subtype-selective thyromimetic designed to bind a mutant thyroid hormone receptor implicated in resistance to thyroid hormone. Journal of the American Chemical Society. 123: 1521-2. PMID 11456736  0.58
2001 Shi Y, Koh JT. Selective regulation of gene expression by an orthogonal estrogen receptor-ligand pair created by polar-group exchange. Chemistry & Biology. 8: 501-10. PMID 11358696 DOI: 10.1016/S1074-5521(01)00028-X  0.654
2000 Xu W, Springfield SA, Koh JT. Highly efficient synthesis of 1-thioglycosides in solution and solid phase using iminophosphorane bases. Carbohydrate Research. 325: 169-76. PMID 10795807 DOI: 10.1016/S0008-6215(99)00327-4  0.707
1999 Koh JT, Putnam M, Tomic-Canic M, McDaniel CM. Selective regulation of gene expression using rationally-modified retinoic acid receptors [16] Journal of the American Chemical Society. 121: 1984-1985. DOI: 10.1021/Ja983988U  0.672
1997 Koh JT, Cornish VW, Schultz PG. An experimental approach to evaluating the role of backbone interactions in proteins using unnatural amino acid mutagenesis. Biochemistry. 36: 11314-22. PMID 9298950 DOI: 10.1021/Bi9707685  0.598
1996 Norman TC, Gray NS, Koh JT, Schultz PG. A Structure-Based Library Approach to Kinase Inhibitors Journal of the American Chemical Society. 118: 7430-7431. DOI: 10.1021/Ja9614934  0.658
1994 Koh JT, Delaude L, Breslow R. Geometric Control of a Pyridoxal-Catalyzed Aldol Condensation Journal of the American Chemical Society. 116: 11234-11240. DOI: 10.1021/Ja00104A004  0.435
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