John T. Koh - Publications

University of Delaware, Newark, DE, United States 
Bioorganic Chemistry, Organic Chemistry, Chemical Biology

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Zhang Y, Mantravadi PK, Jobbagy S, Bao W, Koh JT. Antagonizing the Androgen Receptor with a Biomimetic Acyltransferase. Acs Chemical Biology. PMID 27548116 DOI: 10.1021/acschembio.6b00659  0.8
2012 Ceo LM, Koh JT. Photocaged DNA provides new levels of transcription control. Chembiochem : a European Journal of Chemical Biology. 13: 511-3. PMID 22271631 DOI: 10.1002/cbic.201100683  1
2010 Jain D, Koh JT. A mutant selective anti-estrogen is a pure antagonist on EREs and AP-1 response elements. Bioorganic & Medicinal Chemistry Letters. 20: 5258-61. PMID 20659801 DOI: 10.1016/j.bmcl.2010.06.151  0.96
2010 Sauers DJ, Temburni MK, Biggins JB, Ceo LM, Galileo DS, Koh JT. Light-activated gene expression directs segregation of co-cultured cells in vitro. Acs Chemical Biology. 5: 313-20. PMID 20050613 DOI: 10.1021/cb9002305  1
2008 Zheng J, Hashimoto A, Putnam M, Miller K, Koh JT. Development of a thyroid hormone receptor targeting conjugate. Bioconjugate Chemistry. 19: 1227-34. PMID 18507428 DOI: 10.1021/bc8000326  1
2007 Koh JT, Zheng J. The new biomimetic chemistry: artificial transcription factors. Acs Chemical Biology. 2: 599-601. PMID 17894442 DOI: 10.1021/cb700183s  1
2007 Biggins JB, Hashimoto A, Koh JT. Photocaged agonist for an analogue-specific form of the vitamin D receptor. Chembiochem : a European Journal of Chemical Biology. 8: 799-803. PMID 17393546 DOI: 10.1002/cbic.200600497  0.96
2007 Posner GH, Suh BC, Petersen KS, Dolan P, Agoston ES, Kensler TW, Koh JT, Peleg S. Difluoromethyl analogs of the natural hormone 1α,25-dihydroxyvitamin D3: Design, synthesis, and preliminary biological evaluation Journal of Steroid Biochemistry and Molecular Biology. 103: 213-221. PMID 17218093 DOI: 10.1016/j.jsbmb.2006.12.024  0.96
2007 Biggins JB, Koh JT. Chemical biology of steroid and nuclear hormone receptors. Current Opinion in Chemical Biology. 11: 99-110. PMID 17188557 DOI: 10.1016/j.cbpa.2006.10.042  0.96
2006 Fotos JS, Patel VP, Karin NJ, Temburni MK, Koh JT, Galileo DS. Automated time-lapse microscopy and high-resolution tracking of cell migration. Cytotechnology. 51: 7-19. PMID 19002890 DOI: 10.1007/s10616-006-9006-7  0.96
2005 Link KH, Shi Y, Koh JT. Light activated recombination. Journal of the American Chemical Society. 127: 13088-9. PMID 16173704 DOI: 10.1021/ja0531226  1
2005 Koh JT, Biggins JB. Ligand-receptor engineering and its application towards the complementation of genetic disease and target identification. Current Topics in Medicinal Chemistry. 5: 413-20. PMID 15892683  0.96
2005 Hashimoto A, Shi Y, Drake K, Koh JT. Design and synthesis of complementing ligands for mutant thyroid hormone receptor TRbeta(R320H): a tailor-made approach toward the treatment of resistance to thyroid hormone. Bioorganic & Medicinal Chemistry. 13: 3627-39. PMID 15862991 DOI: 10.1016/j.bmc.2005.03.040  0.96
2005 Shi Y, Ye H, Link KH, Putnam MC, Hubner I, Dowdell S, Koh JT. Mutant-selective thyromimetics for the chemical rescue of thyroid hormone receptor mutants associated with resistance to thyroid hormone. Biochemistry. 44: 4612-26. PMID 15779888 DOI: 10.1021/bi0482349  1
2004 Link KH, Cruz FG, Ye HF, O'reilly KE, Dowdell S, Koh JT. Photo-caged agonists of the nuclear receptors RARgamma and TRbeta provide unique time-dependent gene expression profiles for light-activated gene patterning. Bioorganic & Medicinal Chemistry. 12: 5949-59. PMID 15498671 DOI: 10.1016/j.bmc.2004.08.022  1
2004 Shi Y, Koh JT. Light-activated transcription and repression by using photocaged SERMs. Chembiochem : a European Journal of Chemical Biology. 5: 788-96. PMID 15174161 DOI: 10.1002/cbic.200300823  1
2003 Koh JT. Making virtual screening a reality. Proceedings of the National Academy of Sciences of the United States of America. 100: 6902-3. PMID 12782796 DOI: 10.1073/pnas.1332743100  0.96
2002 Swann SL, Bergh JJ, Farach-Carson MC, Koh JT. Rational design of vitamin D3 analogues which selectively restore activity to a vitamin D receptor mutant associated with rickets. Organic Letters. 4: 3863-6. PMID 12599478 DOI: 10.1021/ol0266931  0.96
2002 Swann SL, Bergh J, Farach-Carson MC, Ocasio CA, Koh JT. Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor. Journal of the American Chemical Society. 124: 13795-805. PMID 12431109 DOI: 10.1021/ja0268377  0.96
2002 Shi Y, Koh JT. Functionally orthogonal ligand-receptor pairs for the selective regulation of gene expression generated by manipulation of charged residues at the ligand-receptor interface of ER alpha and ER beta. Journal of the American Chemical Society. 124: 6921-8. PMID 12059215  1
2001 Ye HF, O'Reilly KE, Koh JT. A subtype-selective thyromimetic designed to bind a mutant thyroid hormone receptor implicated in resistance to thyroid hormone. Journal of the American Chemical Society. 123: 1521-2. PMID 11456736  0.48
2001 Shi Y, Koh JT. Selective regulation of gene expression by an orthogonal estrogen receptor-ligand pair created by polar-group exchange. Chemistry & Biology. 8: 501-10. PMID 11358696  1
2000 Xu W, Springfield SA, Koh JT. Highly efficient synthesis of 1-thioglycosides in solution and solid phase using iminophosphorane bases. Carbohydrate Research. 325: 169-76. PMID 10795807  0.64
1997 Koh JT, Cornish VW, Schultz PG. An experimental approach to evaluating the role of backbone interactions in proteins using unnatural amino acid mutagenesis. Biochemistry. 36: 11314-22. PMID 9298950 DOI: 10.1021/bi9707685  0.96
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