Year |
Citation |
Score |
2018 |
Pham GH, Ou W, Bursulaya B, DiDonato M, Herath A, Jin Y, Hao X, Loren J, Spraggon G, Brock A, Uno T, Geierstanger BH, Cellitti S. Tuning a Protein Labeling Reaction to Achieve Highly Site-Selective Lysine Conjugation. Chembiochem : a European Journal of Chemical Biology. PMID 29388367 DOI: 10.1002/cbic.201700611 |
0.425 |
|
2017 |
Grunewald J, Jin Y, Vance J, Read J, Wang X, Wan Y, Zhou H, Ou W, Klock HE, Peters EC, Uno T, Brock A, Geierstanger BH. Optimization of an Enzymatic Antibody Drug Conjugation Approach based on CoA Analogs. Bioconjugate Chemistry. PMID 28590752 DOI: 10.1021/Acs.Bioconjchem.7B00236 |
0.755 |
|
2015 |
Grunewald J, Klock HE, Cellitti SE, Bursulaya B, McMullan D, Jones DH, Chiu HP, Wang X, Patterson P, Zhou H, Vance J, Nigoghossian E, Tong H, Daniel D, Mallet W, ... ... Uno T, et al. Efficient preparation of site-specific antibody-drug conjugates using phosphopantetheinyl transferases. Bioconjugate Chemistry. PMID 26588668 DOI: 10.1021/Acs.Bioconjchem.5B00558 |
0.748 |
|
2014 |
Grünewald J, Jones DH, Brock A, Chiu HP, Bursulaya B, Ng K, Vo T, Patterson P, Uno T, Hunt J, Spraggon G, Geierstanger BH. Site-specific dual labeling of proteins by using small orthogonal tags at neutral pH. Chembiochem : a European Journal of Chemical Biology. 15: 1787-91. PMID 25044133 DOI: 10.1002/Cbic.201402204 |
0.395 |
|
2013 |
Marsilje TH, Pei W, Chen B, Lu W, Uno T, Jin Y, Jiang T, Kim S, Li N, Warmuth M, Sarkisova Y, Sun F, Steffy A, Pferdekamper AC, Li AG, et al. Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials. Journal of Medicinal Chemistry. 56: 5675-90. PMID 23742252 DOI: 10.1021/Jm400402Q |
0.337 |
|
2012 |
Chiu HP, Grünewald J, Hao X, Brock A, Okach L, Uno T, Geierstanger BH. Simultaneous purification and site-specific modification of pyrroline-carboxy-lysine proteins. Chembiochem : a European Journal of Chemical Biology. 13: 364-6. PMID 22223621 DOI: 10.1002/Cbic.201100684 |
0.774 |
|
2011 |
Ou W, Uno T, Chiu HP, Grünewald J, Cellitti SE, Crossgrove T, Hao X, Fan Q, Quinn LL, Patterson P, Okach L, Jones DH, Lesley SA, Brock A, Geierstanger BH. Site-specific protein modifications through pyrroline-carboxy-lysine residues. Proceedings of the National Academy of Sciences of the United States of America. 108: 10437-42. PMID 21670250 DOI: 10.1073/Pnas.1105197108 |
0.772 |
|
2011 |
Cellitti SE, Ou W, Chiu HP, Grünewald J, Jones DH, Hao X, Fan Q, Quinn LL, Ng K, Anfora AT, Lesley SA, Uno T, Brock A, Geierstanger BH. D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine. Nature Chemical Biology. 7: 528-30. PMID 21525873 DOI: 10.1038/Nchembio.586 |
0.728 |
|
2010 |
Jones DH, Cellitti SE, Hao X, Zhang Q, Jahnz M, Summerer D, Schultz PG, Uno T, Geierstanger BH. Site-specific labeling of proteins with NMR-active unnatural amino acids. Journal of Biomolecular Nmr. 46: 89-100. PMID 19669620 DOI: 10.1007/S10858-009-9365-4 |
0.708 |
|
2009 |
Sharif O, Hu H, Klock H, Hampton EN, Nigoghossian E, Knuth MW, Matzen J, Anderson P, Trager R, Uno T, Glynne RJ, Azarian SM, Caldwell JS, Brinker A. Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4. Analytical Biochemistry. 392: 162-8. PMID 19482004 DOI: 10.1016/J.Ab.2009.05.038 |
0.684 |
|
2008 |
Cellitti SE, Jones DH, Lagpacan L, Hao X, Zhang Q, Hu H, Brittain SM, Brinker A, Caldwell J, Bursulaya B, Spraggon G, Brock A, Ryu Y, Uno T, Schultz PG, et al. In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy Journal of the American Chemical Society. 130: 9268-9281. PMID 18576636 DOI: 10.1021/Ja801602Q |
0.744 |
|
2007 |
Jansma A, Zhang Q, Li B, Ding Q, Uno T, Bursulaya B, Liu Y, Furet P, Gray NS, Geierstanger BH. Verification of a designed intramolecular hydrogen bond in a drug scaffold by nuclear magnetic resonance spectroscopy Journal of Medicinal Chemistry. 50: 5875-5877. PMID 17975906 DOI: 10.1021/jm700983a |
0.353 |
|
2006 |
Zhang Q, Liu Y, Gao F, Ding Q, Cho C, Hur W, Jin Y, Uno T, Joazeiro CA, Gray N. Discovery of EGFR selective 4,6-disubstituted pyrimidines from a combinatorial kinase-directed heterocycle library. Journal of the American Chemical Society. 128: 2182-3. PMID 16478150 DOI: 10.1021/Ja0567485 |
0.565 |
|
1996 |
Fan E, Oei Y, Sweet E, Uno T, Schultz PG. Antibodies with thiol-S-transferase activity Journal of the American Chemical Society. 118: 5474-5475. DOI: 10.1021/Ja9602105 |
0.589 |
|
1994 |
Prudent JR, Uno T, Schultz PG. Expanding the scope of RNA catalysis. Science (New York, N.Y.). 264: 1924-7. PMID 8009223 DOI: 10.1126/Science.8009223 |
0.507 |
|
Low-probability matches (unlikely to be authored by this person) |
2010 |
Wei L, Gao X, Warne R, Hao X, Bussiere D, Gu XJ, Uno T, Liu Y. Design and synthesis of benzoazepin-2-one analogs as allosteric binders targeting the PIF pocket of PDK1. Bioorganic & Medicinal Chemistry Letters. 20: 3897-902. PMID 20627557 DOI: 10.1016/j.bmcl.2010.05.019 |
0.224 |
|
2015 |
Michellys PY, Chen B, Jiang T, Jin Y, Lu W, Marsilje TH, Pei W, Uno T, Zhu X, Wu B, Nguyen TN, Bursulaya B, Lee C, Li N, Kim S, et al. Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 26750252 DOI: 10.1016/j.bmcl.2015.11.049 |
0.126 |
|
2003 |
Boussie TR, Diamond GM, Goh C, Hall KA, LaPointe AM, Leclerc M, Lund C, Murphy V, Shoemaker JA, Tracht U, Turner H, Zhang J, Uno T, Rosen RK, Stevens JC. A fully integrated high-throughput screening methodology for the discovery of new polyolefin catalysts: discovery of a new class of high temperature single-site group (IV) copolymerization catalysts. Journal of the American Chemical Society. 125: 4306-17. PMID 12670253 DOI: 10.1021/Ja020868K |
0.114 |
|
2014 |
Thoma G, Blanz J, Bühlmayer P, Drückes P, Kittelmann M, Smith AB, van Eis M, Vangrevelinghe E, Zerwes HG, Che JJ, He X, Jin Y, Lee CC, Michellys PY, Uno T, et al. Syk inhibitors with high potency in presence of blood. Bioorganic & Medicinal Chemistry Letters. 24: 2278-82. PMID 24726806 DOI: 10.1016/j.bmcl.2014.03.075 |
0.097 |
|
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