Heiko Wurdak - Publications

Affiliations: 
University of Leeds, UK 
Area:
Stem cell and tumor biology

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lucki NC, Villa GR, Vergani N, Bollong MJ, Beyer BA, Lee JW, Anglin JL, Spangenberg SH, Chin EN, Sharma A, Johnson K, Sander PN, Gordon P, Skirboll SL, Wurdak H, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30846550 DOI: 10.1073/pnas.1816626116  0.76
2018 Polson ES, Kuchler VB, Abbosh C, Ross EM, Mathew RK, Beard HA, da Silva B, Holding AN, Ballereau S, Chuntharpursat-Bon E, Williams J, Griffiths HBS, Shao H, Patel A, Davies AJ, ... ... Wurdak H, et al. KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice. Science Translational Medicine. 10. PMID 30111643 DOI: 10.1126/scitranslmed.aar2718  0.76
2015 Hayes J, Thygesen H, Droop A, Hughes TA, Westhead D, Lawler SE, Wurdak H, Short SC. Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation. Oncoscience. 2: 252-62. PMID 25897422 DOI: 10.18632/oncoscience.112  0.76
2013 Guo Y, Partch CL, Key J, Card PB, Pashkov V, Patel A, Bruick RK, Wurdak H, Gardner KH. Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules. Acs Chemical Biology. 8: 626-35. PMID 23240775 DOI: 10.1021/cb300604u  0.76
2011 Lyssiotis CA, Lairson LL, Boitano AE, Wurdak H, Zhu S, Schultz PG. Chemical control of stem cell fate and developmental potential. Angewandte Chemie (International Ed. in English). 50: 200-42. PMID 21184400 DOI: 10.1002/anie.201004284  0.76
2010 Zhu S, Wurdak H, Schultz PG. Directed embryonic stem cell differentiation with small molecules. Future Medicinal Chemistry. 2: 965-73. PMID 21426114 DOI: 10.4155/fmc.10.190  0.76
2010 Wurdak H, Zhu S, Min KH, Aimone L, Lairson LL, Watson J, Chopiuk G, Demas J, Charette B, Halder R, Weerapana E, Cravatt BF, Cline HT, Peters EC, Zhang J, et al. A small molecule accelerates neuronal differentiation in the adult rat. Proceedings of the National Academy of Sciences of the United States of America. 107: 16542-7. PMID 20823227 DOI: 10.1073/pnas.1010300107  0.76
2010 Wurdak H, Zhu S, Romero A, Lorger M, Watson J, Chiang CY, Zhang J, Natu VS, Lairson LL, Walker JR, Trussell CM, Harsh GR, Vogel H, Felding-Habermann B, Orth AP, et al. An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation. Cell Stem Cell. 6: 37-47. PMID 20085741 DOI: 10.1016/j.stem.2009.11.002  0.76
2009 Zhu S, Wurdak H, Wang Y, Galkin A, Tao H, Li J, Lyssiotis CA, Yan F, Tu BP, Miraglia L, Walker J, Sun F, Orth A, Schultz PG, Wu X. A genomic screen identifies TYRO3 as a MITF regulator in melanoma. Proceedings of the National Academy of Sciences of the United States of America. 106: 17025-30. PMID 19805117 DOI: 10.1073/pnas.0909292106  0.76
2009 Zhu S, Wurdak H, Wang J, Lyssiotis CA, Peters EC, Cho CY, Wu X, Schultz PG. A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell. 4: 416-26. PMID 19427291 DOI: 10.1016/j.stem.2009.04.001  0.76
2008 Falk S, Wurdak H, Ittner LM, Ille F, Sumara G, Schmid MT, Draganova K, Lang KS, Paratore C, Leveen P, Suter U, Karlsson S, Born W, Ricci R, Götz M, et al. Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion. Cell Stem Cell. 2: 472-83. PMID 18462697 DOI: 10.1016/j.stem.2008.03.006  0.76
2007 Ille F, Atanasoski S, Falk S, Ittner LM, Märki D, Büchmann-Møller S, Wurdak H, Suter U, Taketo MM, Sommer L. Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord. Developmental Biology. 304: 394-408. PMID 17292876 DOI: 10.1016/j.ydbio.2006.12.045  0.76
2005 Ittner LM, Wurdak H, Schwerdtfeger K, Kunz T, Ille F, Leveen P, Hjalt TA, Suter U, Karlsson S, Hafezi F, Born W, Sommer L. Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells. Journal of Biology. 4: 11. PMID 16403239 DOI: 10.1186/jbiol29  0.76
2005 Kléber M, Lee HY, Wurdak H, Buchstaller J, Riccomagno MM, Ittner LM, Suter U, Epstein DJ, Sommer L. Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. The Journal of Cell Biology. 169: 309-20. PMID 15837799 DOI: 10.1083/jcb.200411095  0.76
2005 Wurdak H, Ittner LM, Lang KS, Leveen P, Suter U, Fischer JA, Karlsson S, Born W, Sommer L. Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes & Development. 19: 530-5. PMID 15741317 DOI: 10.1101/gad.317405  0.76
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