Jennifer l. Harris - Publications

Affiliations: 
Genomics institute of the Novartis Foundation  

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Cheng D, Liu J, Han D, Zhang G, Gao W, Hsieh MH, Ng N, Kasibhatla S, Tompkins C, Li J, Steffy A, Sun F, Li C, Seidel HM, Harris JL, et al. Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors. Acs Medicinal Chemistry Letters. 7: 676-80. PMID 27437076 DOI: 10.1021/acsmedchemlett.6b00038  0.44
2016 Jia Y, Yun CH, Park E, Ercan D, Manuia M, Juarez J, Xu C, Rhee K, Chen T, Zhang H, Palakurthi S, Jang J, Lelais G, DiDonato M, Bursulaya B, ... ... Harris J, et al. Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors. Nature. 534: 129-32. PMID 27251290 DOI: 10.1038/nature17960  0.44
2016 Rudy SF, Brenner JC, Harris JL, Liu J, Che J, Scott MV, Owen JH, Komarck CM, P Graham M, L Bellile E, Bradford CR, Prince ME, Carey TE. In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model. Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'Oto-Rhino-Laryngologie Et De Chirurgie Cervico-Faciale. 45: 26. PMID 27117272 DOI: 10.1186/s40463-016-0140-8  0.44
2016 Jia Y, Juarez J, Li J, Manuia M, Niederst MJ, Tompkins C, Timple N, Vaillancourt MT, Culazzo Pferdekamper A, Lockerman EL, Li C, Anderson J, Costa C, Liao D, Murphy E, ... ... Harris J, et al. EGF816 exerts anticancer effects in non-small cell lung cancer by irreversibly and selectively targeting primary and acquired activating mutations in the EGF receptor. Cancer Research. PMID 26825170 DOI: 10.1158/0008-5472.CAN-15-2581  0.44
2015 Choi HS, Rucker PV, Wang Z, Fan Y, Albaugh P, Chopiuk G, Gessier F, Sun F, Adrian F, Liu G, Hood T, Li N, Jia Y, Che J, McCormack S, ... ... Harris J, et al. (R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors. Acs Medicinal Chemistry Letters. 6: 562-7. PMID 26005534 DOI: 10.1021/acsmedchemlett.5b00050  0.44
2014 Zhou Z, Patel M, Ng N, Hsieh MH, Orth AP, Walker JR, Batalov S, Harris JL, Liu J. Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening. Bmc Cancer. 14: 944. PMID 25495526 DOI: 10.1186/1471-2407-14-944  0.44
2014 Friboulet L, Li N, Katayama R, Lee CC, Gainor JF, Crystal AS, Michellys PY, Awad MM, Yanagitani N, Kim S, Pferdekamper AC, Li J, Kasibhatla S, Sun F, Sun X, ... ... Harris JL, et al. The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer. Cancer Discovery. 4: 662-73. PMID 24675041 DOI: 10.1158/2159-8290.CD-13-0846  0.44
2013 Liu J, Pan S, Hsieh MH, Ng N, Sun F, Wang T, Kasibhatla S, Schuller AG, Li AG, Cheng D, Li J, Tompkins C, Pferdekamper A, Steffy A, Cheng J, ... ... Harris JL, et al. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proceedings of the National Academy of Sciences of the United States of America. 110: 20224-9. PMID 24277854 DOI: 10.1073/pnas.1314239110  0.44
2013 Marsilje TH, Pei W, Chen B, Lu W, Uno T, Jin Y, Jiang T, Kim S, Li N, Warmuth M, Sarkisova Y, Sun F, Steffy A, Pferdekamper AC, Li AG, ... ... Harris JL, et al. Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials. Journal of Medicinal Chemistry. 56: 5675-90. PMID 23742252 DOI: 10.1021/jm400402q  0.44
2013 Walker JR, Pacoma R, Watson J, Ou W, Alves J, Mason DE, Peters EC, Urbina HD, Welzel G, Althage A, Liu B, Tuntland T, Jacobson LH, Harris JL, Schumacher AM. Enhanced proteolytic clearance of plasma Aβ by peripherally administered neprilysin does not result in reduced levels of brain Aβ in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2457-64. PMID 23392674 DOI: 10.1523/JNEUROSCI.3407-12.2013  0.44
2006 Urbina HD, Debaene F, Jost B, Bole-Feysot C, Mason DE, Kuzmic P, Harris JL, Winssinger N. Self-assembled small-molecule microarrays for protease screening and profiling. Chembiochem : a European Journal of Chemical Biology. 7: 1790-7. PMID 17009273 DOI: 10.1002/cbic.200600242  0.44
2005 Winssinger N, Harris JL. Microarray-based functional protein profiling using peptide nucleic acid-encoded libraries. Expert Review of Proteomics. 2: 937-47. PMID 16307522 DOI: 10.1586/14789450.2.6.937  0.44
2005 Harris JL, Winssinger N. PNA encoding (PNA=peptide nucleic acid): from solution-based libraries to organized microarrays. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 6792-801. PMID 16038006 DOI: 10.1002/chem.200500305  0.44
2004 Harris J, Mason DE, Li J, Burdick KW, Backes BJ, Chen T, Shipway A, Van Heeke G, Gough L, Ghaemmaghami A, Shakib F, Debaene F, Winssinger N. Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays. Chemistry & Biology. 11: 1361-72. PMID 15489163 DOI: 10.1016/j.chembiol.2004.08.008  0.44
2004 Winssinger N, Damoiseaux R, Tully DC, Geierstanger BH, Burdick K, Harris JL. PNA-encoded protease substrate microarrays. Chemistry & Biology. 11: 1351-60. PMID 15489162 DOI: 10.1016/j.chembiol.2004.07.015  0.44
2002 Winssinger N, Ficarro S, Schultz PG, Harris JL. Profiling protein function with small molecule microarrays. Proceedings of the National Academy of Sciences of the United States of America. 99: 11139-44. PMID 12167675 DOI: 10.1073/pnas.172286899  0.44
2001 Winssinger N, Harris JL, Backes BJ, Schultz PG. From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling. Angewandte Chemie (International Ed. in English). 40: 3152-3155. PMID 29712061 DOI: 10.1002/1521-3773(20010903)40:17<3152::AID-ANIE3152>3.0.CO;2-P  0.72
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