Sofia Barluenga - Publications

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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Barluenga S, Zambaldo C, Ioannidou HA, Ciobanu M, Morieux P, Daguer JP, Winssinger N. Novel PTP1B inhibitors identified by DNA display of fragment pairs. Bioorganic & Medicinal Chemistry Letters. PMID 26691757 DOI: 10.1016/j.bmcl.2015.11.102  1
2015 Viéville JM, Barluenga S, Winssinger N, Delsuc MA. Duplex formation and secondary structure of γ-PNA observed by NMR and CD. Biophysical Chemistry. PMID 26493008 DOI: 10.1016/j.bpc.2015.09.002  1
2015 Barluenga S, Winssinger N. PNA as a Biosupramolecular Tag for Programmable Assemblies and Reactions. Accounts of Chemical Research. 48: 1319-31. PMID 25947113 DOI: 10.1021/acs.accounts.5b00109  1
2015 Daguer JP, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules. Angewandte Chemie (International Ed. in English). 54: 6057-61. PMID 25772490 DOI: 10.1002/anie.201412276  1
2015 Zambaldo C, Barluenga S, Winssinger N. PNA-encoded chemical libraries. Current Opinion in Chemical Biology. 26: 8-15. PMID 25621730 DOI: 10.1016/j.cbpa.2015.01.005  1
2014 Novoa A, Machida T, Barluenga S, Imberty A, Winssinger N. PNA-encoded synthesis (PES) of a 10 000-member hetero-glycoconjugate library and microarray analysis of diverse lectins. Chembiochem : a European Journal of Chemical Biology. 15: 2058-65. PMID 25158314 DOI: 10.1002/cbic.201402280  1
2014 Novoa A, Eierhoff T, Topin J, Varrot A, Barluenga S, Imberty A, Römer W, Winssinger N. A LecA ligand identified from a galactoside-conjugate array inhibits host cell invasion by Pseudomonas aeruginosa. Angewandte Chemie (International Ed. in English). 53: 8885-9. PMID 25044671 DOI: 10.1002/anie.201402831  1
2014 Winssinger N, Gorska K, Ciobanu M, Daguer JP, Barluenga S. Assembly of PNA-tagged small molecules, peptides, and carbohydrates onto DNA templates: programming the combinatorial pairing and inter-ligand distance. Methods in Molecular Biology (Clifton, N.J.). 1050: 95-110. PMID 24297353 DOI: 10.1007/978-1-62703-553-8_8  1
2014 Duplan V, Serba C, Garcia J, Valot G, Barluenga S, Hoerlé M, Cuendet M, Winssinger N. Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway. Organic & Biomolecular Chemistry. 12: 370-5. PMID 24263232 DOI: 10.1039/c3ob42049c  1
2013 Barluenga S, Winssinger N. Picture perfect: DNA-templated photoaffinity labeling. Chembiochem : a European Journal of Chemical Biology. 14: 1927-8. PMID 24006240 DOI: 10.1002/cbic.201300416  1
2013 Novoa A, Barluenga S, Serba C, Winssinger N. Solid phase synthesis of glycopeptides using Shoda's activation of unprotected carbohydrates. Chemical Communications (Cambridge, England). 49: 7608-10. PMID 23882465 DOI: 10.1039/c3cc43458c  1
2013 Kazane SA, Axup JY, Kim CH, Ciobanu M, Wold ED, Barluenga S, Hutchins BA, Schultz PG, Winssinger N, Smider VV. Self-assembled antibody multimers through peptide nucleic acid conjugation. Journal of the American Chemical Society. 135: 340-6. PMID 23210862 DOI: 10.1021/ja309505c  1
2012 Chouikhi D, Ciobanu M, Zambaldo C, Duplan V, Barluenga S, Winssinger N. Expanding the scope of PNA-encoded synthesis (PES): Mtt-protected PNA fully orthogonal to fmoc chemistry and a broad array of robust diversity-generating reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 12698-704. PMID 22915361 DOI: 10.1002/chem.201201337  1
2012 Karthikeyan G, Zambaldo C, Barluenga S, Zoete V, Karplus M, Winssinger N. Asymmetric synthesis of pochonin E and F, revision of their proposed structure, and their conversion to potent Hsp90 inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8978-86. PMID 22696415 DOI: 10.1002/chem.201200546  1
2012 Valot G, Garcia J, Duplan V, Serba C, Barluenga S, Winssinger N. Diversity-oriented synthesis of diverse polycyclic scaffolds inspired by the logic of sesquiterpene lactones biosynthesis. Angewandte Chemie (International Ed. in English). 51: 5391-4. PMID 22517777 DOI: 10.1002/anie.201201157  1
2012 Daguer JP, Ciobanu M, Barluenga S, Winssinger N. Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries. Organic & Biomolecular Chemistry. 10: 1502-5. PMID 22237952 DOI: 10.1039/c2ob06880j  1
2012 Hamidi A, von Bulow V, Hamidi R, Winssinger N, Barluenga S, Heldin CH, Landström M. Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli. The Journal of Biological Chemistry. 287: 123-33. PMID 22069318 DOI: 10.1074/jbc.M111.285122  1
2012 Garcia J, Barluenga S, Gorska K, Sasse F, Winssinger N. Synthesis of deguelin-biotin conjugates and investigation into deguelin's interactions. Bioorganic & Medicinal Chemistry. 20: 672-80. PMID 22037048 DOI: 10.1016/j.bmc.2011.09.064  1
2011 Ciobanu M, Huang KT, Daguer JP, Barluenga S, Chaloin O, Schaeffer E, Mueller CG, Mitchell DA, Winssinger N. Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells. Chemical Communications (Cambridge, England). 47: 9321-3. PMID 21785785 DOI: 10.1039/c1cc13213j  1
2011 Gorska K, Manicardi A, Barluenga S, Winssinger N. DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker. Chemical Communications (Cambridge, England). 47: 4364-6. PMID 21369617 DOI: 10.1039/c1cc10222b  1
2011 Leproult E, Barluenga S, Moras D, Wurtz JM, Winssinger N. Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors. Journal of Medicinal Chemistry. 54: 1347-55. PMID 21322567 DOI: 10.1021/jm101396q  1
2011 Huang KT, Gorska K, Alvarez S, Barluenga S, Winssinger N. Combinatorial self-assembly of glycan fragments into microarrays. Chembiochem : a European Journal of Chemical Biology. 12: 56-60. PMID 21154493 DOI: 10.1002/cbic.201000567  1
2010 Grad I, Cederroth CR, Walicki J, Grey C, Barluenga S, Winssinger N, De Massy B, Nef S, Picard D. The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse. Plos One. 5: e15770. PMID 21209834 DOI: 10.1371/journal.pone.0015770  1
2010 Zhu H, Woolfenden S, Bronson RT, Jaffer ZM, Barluenga S, Winssinger N, Rubenstein AE, Chen R, Charest A. The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme. Molecular Cancer Therapeutics. 9: 2618-26. PMID 20643786 DOI: 10.1158/1535-7163.MCT-10-0248  1
2010 Barluenga S, Jogireddy R, Koripelly GK, Winssinger N. In vivo efficacy of natural product-inspired irreversible kinase inhibitors. Chembiochem : a European Journal of Chemical Biology. 11: 1692-9. PMID 20623569 DOI: 10.1002/cbic.201000205  1
2010 Garcia J, Barluenga S, Beebe K, Neckers L, Winssinger N. Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 9767-71. PMID 20572190 DOI: 10.1002/chem.201001080  1
2010 Chouikhi D, Barluenga S, Winssinger N. Clickable peptide nucleic acids (cPNA) with tunable affinity. Chemical Communications (Cambridge, England). 46: 5476-8. PMID 20571635 DOI: 10.1039/c0cc01081b  1
2010 Jogireddy R, Barluenga S, Winssinger N. Molecular editing of kinase-targeting resorcylic acid lactones (RAL): Fluoroenone RAL. Chemmedchem. 5: 670-3. PMID 20209566 DOI: 10.1002/cmdc.201000047  1
2009 Winssinger N, Fontaine JG, Barluenga S. Hsp90 inhibition with resorcyclic acid lactones (RALs). Current Topics in Medicinal Chemistry. 9: 1419-35. PMID 19860733 DOI: 10.2174/156802609789895665  1
2009 Barluenga S, Fontaine JG, Wang C, Aouadi K, Chen R, Beebe K, Neckers L, Winssinger N. Inhibition of HSP90 with pochoximes: SAR and structure-based insights. Chembiochem : a European Journal of Chemical Biology. 10: 2753-9. PMID 19856365 DOI: 10.1002/cbic.200900494  1
2009 Jogireddy R, Dakas PY, Valot G, Barluenga S, Winssinger N. Synthesis of a resorcylic acid lactone (RAL) library using fluorous-mixture synthesis and profile of its selectivity against a panel of kinases. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 11498-506. PMID 19821461 DOI: 10.1002/chem.200901375  1
2009 Dakas PY, Jogireddy R, Valot G, Barluenga S, Winssinger N. Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 11490-7. PMID 19821460 DOI: 10.1002/chem.200901373  1
2009 Spichty M, Taly A, Hagn F, Kessler H, Barluenga S, Winssinger N, Karplus M. The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR 15N chemical shifts. Biophysical Chemistry. 143: 111-23. PMID 19482409 DOI: 10.1016/j.bpc.2009.04.003  1
2009 Wang C, Barluenga S, Koripelly GK, Fontaine JG, Chen R, Yu JC, Shen X, Chabala JC, Heck JV, Rubenstein A, Winssinger N. Synthesis of pochoxime prodrugs as potent HSP90 inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 3836-40. PMID 19410458 DOI: 10.1016/j.bmcl.2009.04.030  1
2008 García-Cuadrado D, Barluenga S, Winssinger N. Diversity-oriented synthesis of novel polycyclic scaffolds using polymer-bound reagents. Chemical Communications (Cambridge, England). 4619-21. PMID 18815703 DOI: 10.1039/b807869f  1
2008 Barluenga S, Wang C, Fontaine JG, Aouadi K, Beebe K, Tsutsumi S, Neckers L, Winssinger N. Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor. Angewandte Chemie (International Ed. in English). 47: 4432-5. PMID 18435518 DOI: 10.1002/anie.200800233  1
2007 Dakas PY, Barluenga S, Totzke F, Zirrgiebel U, Winssinger N. Modular synthesis of radicicol A and related resorcylic acid lactones, potent kinase inhibitors. Angewandte Chemie (International Ed. in English). 46: 6899-902. PMID 17676571 DOI: 10.1002/anie.200702406  1
2007 Winssinger N, Barluenga S. Chemistry and biology of resorcylic acid lactones. Chemical Communications (Cambridge, England). 22-36. PMID 17279252 DOI: 10.1039/b610344h  1
2006 Moulin E, Barluenga S, Totzke F, Winssinger N. Diversity-oriented synthesis of pochonins and biological evaluation against a panel of kinases. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 8819-34. PMID 16953513 DOI: 10.1002/chem.200600553  1
2006 Barluenga S, Dakas PY, Ferandin Y, Meijer L, Winssinger N. Modular asymmetric synthesis of aigialomycin D, a kinase-inhibitory scaffold. Angewandte Chemie (International Ed. in English). 45: 3951-4. PMID 16683294 DOI: 10.1002/anie.200600593  1
2005 Moulin E, Barluenga S, Winssinger N. Concise synthesis of pochonin A, an HSP90 inhibitor. Organic Letters. 7: 5637-9. PMID 16321010 DOI: 10.1021/ol052263+  1
2005 Barluenga S, Moulin E, Lopez P, Winssinger N. Solution- and solid-phase synthesis of radicicol (monorden) and pochonin C. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 4935-52. PMID 15940738 DOI: 10.1002/chem.200500160  1
2005 Moulin E, Zoete V, Barluenga S, Karplus M, Winssinger N. Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues. Journal of the American Chemical Society. 127: 6999-7004. PMID 15884943 DOI: 10.1021/ja043101w  1
2004 Barluenga S, Lopez P, Moulin E, Winssinger N. Modular asymmetric synthesis of pochonin C. Angewandte Chemie (International Ed. in English). 43: 3467-70. PMID 15221842 DOI: 10.1002/anie.200454108  1
2004 Barluenga S, Simonsen KB, Littlefield ES, Ayida BK, Vourloumis D, Winters GC, Takahashi M, Shandrick S, Zhao Q, Han Q, Hermann T. Rational design of azepane-glycoside antibiotics targeting the bacterial ribosome. Bioorganic & Medicinal Chemistry Letters. 14: 713-8. PMID 14741274 DOI: 10.1016/j.bmcl.2003.11.028  1
2002 Simonsen KB, Ayida BK, Vourloumis D, Takahashi M, Winters GC, Barluenga S, Qamar S, Shandrick S, Zhao Q, Hermann T. Novel paromamine derivatives exploring shallow-groove recognition of ribosomal-decoding-site RNA. Chembiochem : a European Journal of Chemical Biology. 3: 1223-8. PMID 12465030 DOI: 10.1002/1439-7633(20021202)3:12<1223::AID-CBIC1223>3.0.CO;2-W  1
2002 Vourloumis D, Takahashi M, Winters GC, Simonsen KB, Ayida BK, Barluenga S, Qamar S, Shandrick S, Zhao Q, Hermann T. Novel 2,5-dideoxystreptamine derivatives targeting the ribosomal decoding site RNA. Bioorganic & Medicinal Chemistry Letters. 12: 3367-72. PMID 12419363 DOI: 10.1016/S0960-894X(02)00759-X  1
2002 Nicholas GM, Eckman LL, Ray S, Hughes RO, Pfefferkorn JA, Barluenga S, Nicolaou KC, Bewley CA. Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase. Bioorganic & Medicinal Chemistry Letters. 12: 2487-90. PMID 12161164 DOI: 10.1016/S0960-894X(02)00385-2  1
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