Guangyan Du - Publications

Affiliations: 
Dana Farber Cancer Institute, Boston, MA, United States 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Powell CE, Du G, Bushman JW, He Z, Zhang T, Fischer ES, Gray NS. Selective degradation-inducing probes for studying cereblon (CRBN) biology. Rsc Medicinal Chemistry. 12: 1381-1390. PMID 34458741 DOI: 10.1039/d0md00382d  1
2021 Du G, Jiang J, Wu Q, Henning NJ, Donovan KA, Yue H, Che J, Lu W, Fischer ES, Bardeesy N, Zhang T, Gray NS. Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2. Angewandte Chemie (International Ed. in English). PMID 33915015 DOI: 10.1002/anie.202101328  1
2020 Powell CE, Du G, Che J, He Z, Donovan KA, Yue H, Wang ES, Nowak RP, Zhang T, Fischer ES, Gray NS. Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. Acs Chemical Biology. PMID 32865967 DOI: 10.1021/Acschembio.0C00520  1
2020 Gurbani D, Du G, Henning NJ, Rao S, Bera AK, Zhang T, Gray NS, Westover KD. Structure and Characterization of a Covalent Inhibitor of Src Kinase. Frontiers in Molecular Biosciences. 7: 81. PMID 32509799 DOI: 10.3389/Fmolb.2020.00081  1
2020 Xiao H, Jedrychowski MP, Schweppe DK, Huttlin EL, Yu Q, Heppner DE, Li J, Long J, Mills EL, Szpyt J, He Z, Du G, Garrity R, Reddy A, Vaites LP, et al. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. PMID 32109415 DOI: 10.1016/J.Cell.2020.02.012  1
2020 Du G, Rao S, Gurbani D, Henning NJ, Jiang J, Che J, Yang A, Ficarro SB, Marto JA, Aguirre AJ, Sorger PK, Westover KD, Zhang T, Gray NS. Structure-based design of a potent and selective covalent inhibitor for SRC kinase that targets a p-Loop cysteine. Journal of Medicinal Chemistry. PMID 31935084 DOI: 10.1021/Acs.Jmedchem.9B01502  1
2019 de Wispelaere M, Du G, Donovan KA, Zhang T, Eleuteri NA, Yuan JC, Kalabathula J, Nowak RP, Fischer ES, Gray NS, Yang PL. Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations. Nature Communications. 10: 3468. PMID 31371704 DOI: 10.1038/S41467-019-11429-W  1
2019 Scott DA, Hatcher JM, Liu H, Fu M, Du G, Fontán L, Us I, Casalena G, Qiao Q, Wu H, Melnick A, Gray NS. Quinoline and thiazolopyridine allosteric inhibitors of MALT1. Bioorganic & Medicinal Chemistry Letters. PMID 31129051 DOI: 10.1016/J.Bmcl.2019.05.040  1
2019 Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Li T, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, et al. Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chemical Biology. PMID 30982749 DOI: 10.1016/J.Chembiol.2019.02.021  1
2019 Hatcher JM, Du G, Fontán L, Us I, Qiao Q, Chennamadhavuni S, Shao J, Wu H, Melnick A, Gray NS, Scott DA. Peptide-based covalent inhibitors of MALT1 paracaspase. Bioorganic & Medicinal Chemistry Letters. PMID 30954428 DOI: 10.1016/J.Bmcl.2019.03.046  1
2019 Rao S, Du G, Hafner M, Subramanian K, Sorger PK, Gray NS. A multi-targeted probe-based strategy to identify signaling vulnerabilities in cancers. The Journal of Biological Chemistry. PMID 30858179 DOI: 10.1074/Jbc.Ra118.006805  1
2018 Huang J, Bao W, Huang S, Yang W, Lizhi Z, Du G, Lee CS. Formal Synthesis of (+)-Phomactin A. Organic Letters. PMID 30480457 DOI: 10.1021/acs.orglett.8b03242  0.04
2018 Fontán L, Qiao Q, Hatcher JM, Casalena G, Us I, Teater M, Durant M, Du G, Xia M, Bilchuk N, Chennamadhavuni S, Palladino G, Inghirami G, Philippar U, Wu H, et al. Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth. The Journal of Clinical Investigation. PMID 30024860 DOI: 10.1172/Jci99436  1
2018 Du G, Fu L, Jia J, Pang X, Yu H, Zhang Y, Fan G, Gao X, Han L. Validated UPLC-MS/MS method for quantification of seven compounds in rat plasma and tissues: Application to pharmacokinetic and tissue distribution studies in rats after oral administration of extract of Eclipta prostrata L. Biomedical Chromatography : Bmc. PMID 29349861 DOI: 10.1002/bmc.4191  0.2
2017 Wang G, Peng Y, Lou L, Xing P, Du G. Selective vesicle aggregation achieved via the self-assembly of terpyridine-based building blocks. Soft Matter. PMID 28492660 DOI: 10.1039/c7sm00504k  0.2
2017 Sang M, Du G, Hao J, Wang L, Liu E, Zhang Y, Wang T, Gao X, Han L. Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology. Journal of Pharmaceutical and Biomedical Analysis. 139: 37-43. PMID 28273649 DOI: 10.1016/j.jpba.2017.02.048  0.16
2017 Rao S, Li T, Everley R, Du G, Sorger P, Gray N. Abstract 1222: Developing kinase inhibitors with polypharmacological profiles for the treatment of resistant cancers Cancer Research. 77: 1222-1222. DOI: 10.1158/1538-7445.Am2017-1222  1
2016 Liang Z, Tsoi TH, Chan CF, Dai L, Wu Y, Du G, Zhu L, Lee CS, Wong WT, Law GL, Wong KL. A smart "off-on" gate for the detection of hydrogen sulphide with Cu(ii)-assisted europium emission. Chemical Science. 7: 2151-2156. PMID 29899943 DOI: 10.1039/C5Sc04091D  0.04
2016 Tan L, Gurbani D, Weisberg EL, Jones DS, Rao S, Singer WD, Bernard FM, Mowafy S, Jenney A, Du G, Nonami A, Griffin JD, Lauffenburger DA, Westover KD, Sorger PK, et al. Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 28038940 DOI: 10.1016/J.Bmc.2016.11.034  1
2016 Tan L, Gurbani D, Weisberg EL, Hunter JC, Li L, Jones DS, Ficarro SB, Mowafy S, Tam CP, Rao S, Du G, Griffin JD, Sorger PK, Marto JA, Westover KD, et al. Structure-guided development of covalent TAK1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 28011204 DOI: 10.1016/J.Bmc.2016.11.035  1
2016 Hu X, Zhao J, Qian H, Du G, Kelly M, Yang H. Radiological and pathological analysis of LDCT screen detected and surgically resected sub-centimetre lung nodules in 44 asymptomatic patients. European Journal of Radiology Open. 3: 223-9. PMID 27579337 DOI: 10.1016/j.ejro.2016.08.001  1
2015 Goujon A, Du G, Moulin E, Fuks G, Maaloum M, Buhler E, Giuseppone N. Hierarchical Self-Assembly of Supramolecular Muscle-Like Fibers. Angewandte Chemie (International Ed. in English). PMID 26582752 DOI: 10.1002/Anie.201509813  1
2015 Du G, Bao W, Huang J, Huang S, Yue H, Yang W, Zhu L, Liang Z, Lee CS. Enantioselective Synthesis of the ABC-Tricyclic Core of Phomactin A by a γ-Hydroxylation Strategy. Organic Letters. 17: 2062-5. PMID 25860178 DOI: 10.1021/acs.orglett.5b00586  1
2015 Busseron E, Cid JJ, Wolf A, Du G, Moulin E, Fuks G, Maaloum M, Polavarapu P, Ruff A, Saur AK, Ludwigs S, Giuseppone N. Light-controlled morphologies of self-assembled triarylamine-fullerene conjugates. Acs Nano. 9: 2760-72. PMID 25734231 DOI: 10.1021/Nn506646M  0.01
2015 Wolf A, Moulin E, Cid JJ, Goujon A, Du G, Busseron E, Fuks G, Giuseppone N. pH and light-controlled self-assembly of bistable [c2] daisy chain rotaxanes. Chemical Communications (Cambridge, England). 51: 4212-5. PMID 25661046 DOI: 10.1039/C4Cc10331A  0.01
2015 Yang W, Cao J, Zhang M, Lan R, Zhu L, Du G, He S, Lee CS. Systemic study on the biogenic pathways of yezo’otogirins: total synthesis and antitumor activities of (±)-yezo’otogirin C and its structural analogues. The Journal of Organic Chemistry. 80: 836-46. PMID 25517288 DOI: 10.1021/jo502267g  0.16
2014 He S, Yang W, Zhu L, Du G, Lee CS. Bioinspired total synthesis of (±)-yezo'otogirin C. Organic Letters. 16: 496-9. PMID 24377836 DOI: 10.1021/ol403374h  0.12
2013 Zhu L, Han Y, Du G, Lee CS. A bifunctional Lewis acid induced cascade cyclization to the tricyclic core of ent-kaurenoids and its application to the formal synthesis of (±)-platensimycin. Organic Letters. 15: 524-7. PMID 23327558 DOI: 10.1021/ol3033412  0.08
2012 Du G, Moulin E, Jouault N, Buhler E, Giuseppone N. Muscle-like supramolecular polymers: integrated motion from thousands of molecular machines. Angewandte Chemie (International Ed. in English). 51: 12504-8. PMID 23081866 DOI: 10.1002/Anie.201206571  0.01
2011 Huang S, Du G, Lee CS. Construction of the tricyclic furanochroman skeleton of phomactin A via the Prins/Conia-ene cascade cyclization approach. The Journal of Organic Chemistry. 76: 6534-41. PMID 21739982 DOI: 10.1021/jo200644t  0.08
2010 Li Y, Liu J, Du G, Yan H, Wang H, Zhang H, An W, Zhao W, Sun T, Xin F, Kong L, Li Y, Hao A, Hao J. Reversible heat-set organogel based on supramolecular interactions of beta-cyclodextrin in N,N-dimethylformamide. The Journal of Physical Chemistry. B. 114: 10321-6. PMID 20701367 DOI: 10.1021/Jp1017373  0.28
2008 Shen J, Hao A, Du G, Zhang H, Sun H. A convenient preparation of 6-oligo(lactic acid)cyclomaltoheptaose as kinetically degradable derivative for controlled release of amoxicillin. Carbohydrate Research. 343: 2517-22. PMID 18619585 DOI: 10.1016/J.Carres.2008.06.010  0.16
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