Year |
Citation |
Score |
2019 |
Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM. p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. Science (New York, N.Y.). 366. PMID 31831640 DOI: 10.1126/Science.Aaw2106 |
0.62 |
|
2019 |
Yueh C, Rettenmaier J, Xia B, Hall DR, Alekseenko A, Porter KA, Barkovich K, Keseru G, Whitty A, Wells JA, Vajda S, Kozakov D. Kinase Atlas: Druggability Analysis of Potential Allosteric Sites in Kinases. Journal of Medicinal Chemistry. PMID 31274316 DOI: 10.1021/Acs.Jmedchem.9B00089 |
0.617 |
|
2018 |
Ocasio CA, Warkentin AA, McIntyre PJ, Barkovich KJ, Vesely C, Spencer J, Shokat KM, Bayliss R. Type II kinase inhibitors targeting Cys-gatekeeper kinases display orthogonality with wild type and Ala/Gly-gatekeeper kinases. Acs Chemical Biology. PMID 30239186 DOI: 10.1021/Acschembio.8B00592 |
0.752 |
|
2018 |
Barkovich KJ, Moore MK, Hu Q, Shokat KM. Chemical genetic inhibition of DEAD-box proteins using covalent complementarity. Nucleic Acids Research. PMID 30102385 DOI: 10.1093/Nar/Gky706 |
0.564 |
|
2016 |
Zhang J, Yao TW, Hashizume R, Hariono S, Barkovich KJ, Fan QW, Prados M, James CD, Weiss WA, Nicolaides T. Combined BRAF(V600E) and MEK blockade for BRAF(V600E)-mutant gliomas. Journal of Neuro-Oncology. PMID 27848137 DOI: 10.1007/S11060-016-2333-4 |
0.457 |
|
2016 |
Floor SN, Barkovich KJ, Condon KJ, Shokat KM, Doudna JA. Analog sensitive chemical inhibition of the DEAD-box protein DDX3. Protein Science : a Publication of the Protein Society. 25: 638-49. PMID 26650549 DOI: 10.1002/Pro.2857 |
0.478 |
|
2012 |
Barkovich KJ, Hariono S, Garske AL, Zhang J, Blair JA, Fan QW, Shokat KM, Nicolaides T, Weiss WA. Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers. Cancer Discovery. 2: 450-7. PMID 22588882 DOI: 10.1158/2159-8290.Cd-11-0287 |
0.641 |
|
2011 |
Nicolaides TP, Li H, Solomon DA, Hariono S, Hashizume R, Barkovich K, Baker SJ, Paugh BS, Jones C, Forshew T, Hindley GF, Hodgson JG, Kim JS, Rowitch DH, Weiss WA, et al. Targeted therapy for BRAFV600E malignant astrocytoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 7595-604. PMID 22038996 DOI: 10.1158/1078-0432.Ccr-11-1456 |
0.45 |
|
2010 |
Nicolaides TP, Barkovich K, Hariono S, Garske A, Fan QW, Shokat K, Weiss WA. Abstract 1973: Targeting activated alleles of EGFR derived from glioma and lung cancer: Correlating kinase active-site occupancy with efficacy Cancer Research. 70: 1973-1973. DOI: 10.1158/1538-7445.Am10-1973 |
0.689 |
|
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