Jeff W. Jacobs - Publications

Affiliations: 
Ardelyx, Inc. 
Area:
Drug discovery and development

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bijlsma JW, Welsing PM, Woodworth TG, Middelink LM, Pethö-Schramm A, Bernasconi C, Borm ME, Wortel CH, Ter Borg EJ, Jahangier ZN, van der Laan WH, Bruyn GA, Baudoin P, Wijngaarden S, Vos PA, ... ... Jacobs JW, et al. Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination (U-Act-Early): a multicentre, randomised, double-blind, double-dummy, strategy trial. Lancet (London, England). PMID 27287832 DOI: 10.1016/S0140-6736(16)30363-4  0.36
2016 Nair SC, Jacobs JW, Bakker MF, Jahangier ZN, Bijlsma JW, Laar JM, Lafeber FP, Welsing PM. Determining the Lowest Optimally Effective Methotrexate Dose for Individual RA Patients Using Their Dose Response Relation in a Tight Control Treatment Approach. Plos One. 11: e0148791. PMID 26987073 DOI: 10.1371/journal.pone.0148791  0.36
2016 van der Goes MC, Jacobs JW, Bijlsma JW. Rediscovering the therapeutic use of glucocorticoids in rheumatoid arthritis. Current Opinion in Rheumatology. 28: 289-96. PMID 26962704 DOI: 10.1097/BOR.0000000000000278  0.36
2016 van Onna M, Ten Cate DF, Tsoi KL, Meier AJ, Jacobs JW, Westgeest AA, Meijer PB, van Beek MC, Rensen WH, Bijlsma JW. Assessment of disease activity in patients with rheumatoid arthritis using optical spectral transmission measurements, a non-invasive imaging technique. Annals of the Rheumatic Diseases. 75: 511-8. PMID 26452538 DOI: 10.1136/annrheumdis-2015-207315  0.36
2015 Bijlsma JW, Jacobs JW, Buttgereit F. Glucocorticoids in the treatment of rheumatoid arthritis. Clinical and Experimental Rheumatology. 33: S34-6. PMID 26457916  0.36
2015 Nair SC, Welsing PM, Jacobs JW, van Laar JM, Rensen WH, Ardine de Wit G, Bijlsma JW, Lafeber FP. Economic evaluation of a tight-control treatment strategy using an imaging device (handscan) for monitoring joint inflammation in early rheumatoid arthritis. Clinical and Experimental Rheumatology. PMID 26343274  0.36
2015 Jurgens MS, Jacobs JW, Boers M, van der Goes MC, van der Veen MJ, Lafeber FP, Bijlsma JW. Alternative Ways to Quantify Sustained Remission: Applying the Continuity Rewarded Score and Patient Vector Graph. Arthritis Care & Research. 67: 1471-4. PMID 25708452 DOI: 10.1002/acr.22565  0.36
2015 Jurgens MS, Overman CL, Jacobs JW, Geenen R, Cuppen BV, Marijnissen AC, Bijlsma JW, Welsing PM, Lafeber FP, van Laar JM. Contribution of the subjective components of the disease activity score to the response to biologic treatment in rheumatoid arthritis. Arthritis Care & Research. 67: 923-8. PMID 25504811 DOI: 10.1002/acr.22532  0.36
2014 van der Goes MC, Jacobs JW, Bijlsma JW. The value of glucocorticoid co-therapy in different rheumatic diseases--positive and adverse effects. Arthritis Research & Therapy. 16: S2. PMID 25608693 DOI: 10.1186/ar4686  0.36
2014 Bijlsma JW, Jacobs JW. Glucocorticoids in the treatment of rheumatoid arthritis: still used after 65 years. Annals of the New York Academy of Sciences. 1318: 27-31. PMID 24641732 DOI: 10.1111/nyas.12394  0.36
2014 Jurgens MS, Welsing PM, Geenen R, Bakker MF, Schenk Y, de Man YA, Bijlsma JW, Lafeber FP, Jacobs JW. The separate impact of tight control schemes and disease activity on quality of life in patients with early rheumatoid arthritis: results from the CAMERA trials. Clinical and Experimental Rheumatology. 32: 369-76. PMID 24564933  0.36
2014 Overman CL, Jurgens MS, Bossema ER, Jacobs JW, Bijlsma JW, Geenen R. Change of psychological distress and physical disability in patients with rheumatoid arthritis over the last two decades. Arthritis Care & Research. 66: 671-8. PMID 24302705 DOI: 10.1002/acr.22211  0.36
2013 Duru N, van der Goes MC, Jacobs JW, Andrews T, Boers M, Buttgereit F, Caeyers N, Cutolo M, Halliday S, Da Silva JA, Kirwan JR, Ray D, Rovensky J, Severijns G, Westhovens R, et al. EULAR evidence-based and consensus-based recommendations on the management of medium to high-dose glucocorticoid therapy in rheumatic diseases. Annals of the Rheumatic Diseases. 72: 1905-13. PMID 23873876 DOI: 10.1136/annrheumdis-2013-203249  0.36
2013 Bossema ER, van Middendorp H, Jacobs JW, Bijlsma JW, Geenen R. Influence of weather on daily symptoms of pain and fatigue in female patients with fibromyalgia: a multilevel regression analysis. Arthritis Care & Research. 65: 1019-25. PMID 23737338 DOI: 10.1002/acr.22008  0.36
2013 van der Goes MC, Jacobs JW, Jurgens MS, Bakker MF, van der Veen MJ, van der Werf JH, Welsing PM, Bijlsma JW. Are changes in bone mineral density different between groups of early rheumatoid arthritis patients treated according to a tight control strategy with or without prednisone if osteoporosis prophylaxis is applied? Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 24: 1429-36. PMID 23011680 DOI: 10.1007/s00198-012-2073-z  0.36
2013 Jurgens MS, Jacobs JW, Geenen R, Bossema ER, Bakker MF, Bijlsma JW, van Albada-Kuipers IA, Ehrlich JC, Lafeber FP, Welsing PM. Increase of body mass index in a tight controlled methotrexate-based strategy with prednisone in early rheumatoid arthritis: side effect of the prednisone or better control of disease activity? Arthritis Care & Research. 65: 88-93. PMID 22807253 DOI: 10.1002/acr.21797  0.36
2012 Jurgens MS, Welsing PM, Jacobs JW. Overview and analysis of treat-to-target trials in rheumatoid arthritis reporting on remission. Clinical and Experimental Rheumatology. 30: S56-63. PMID 23078808  0.36
2012 Bakker MF, Cavet G, Jacobs JW, Bijlsma JW, Haney DJ, Shen Y, Hesterberg LK, Smith DR, Centola M, van Roon JA, Lafeber FP, Welsing PM. Performance of a multi-biomarker score measuring rheumatoid arthritis disease activity in the CAMERA tight control study. Annals of the Rheumatic Diseases. 71: 1692-7. PMID 22596166 DOI: 10.1136/annrheumdis-2011-200963  0.36
2012 van der Goes MC, Straub RH, Wenting MJ, Capellino S, Jacobs JW, Jahangier ZN, Rauch L, Bijlsma JW, Lafeber FP. Intra-articular glucocorticoid injections decrease the number of steroid hormone receptor positive cells in synovial tissue of patients with persistent knee arthritis. Annals of the Rheumatic Diseases. 71: 1552-8. PMID 22504564 DOI: 10.1136/annrheumdis-2011-201019  0.36
2012 Bakker MF, Jacobs JW, Kruize AA, van der Veen MJ, van Booma-Frankfort C, Vreugdenhil SA, Bijlsma JW, Lafeber FP, Welsing PM. Misclassification of disease activity when assessing individual patients with early rheumatoid arthritis using disease activity indices that do not include joints of feet. Annals of the Rheumatic Diseases. 71: 830-5. PMID 22128075 DOI: 10.1136/annrheumdis-2011-146670  0.36
2012 Ton E, Bakker MF, Verstappen SM, Ter Borg EJ, van Albada-Kuipers IA, Schenk Y, van der Veen MJ, Bijlsma JW, Jacobs JW. Look beyond the disease activity score of 28 joints (DAS28): tender points influence the DAS28 in patients with rheumatoid arthritis. The Journal of Rheumatology. 39: 22-7. PMID 22002014 DOI: 10.3899/jrheum.110072  0.36
2012 Overman CL, Bossema ER, van Middendorp H, Wijngaards-de Meij L, Verstappen SM, Bulder M, Jacobs JW, Bijlsma JW, Geenen R. The prospective association between psychological distress and disease activity in rheumatoid arthritis: a multilevel regression analysis. Annals of the Rheumatic Diseases. 71: 192-7. PMID 21917827 DOI: 10.1136/annrheumdis-2011-200338  0.36
2011 Jurgens MS, Jacobs JW, Bijlsma JW. The use of conventional disease-modifying anti-rheumatic drugs in established RA. Best Practice & Research. Clinical Rheumatology. 25: 523-33. PMID 22137922 DOI: 10.1016/j.berh.2011.10.006  0.36
2011 van der Goes MC, Jacobs JW, Bijlsma JW. Toward safer treatment with glucocorticoids: via patient and rheumatologist perspectives to recommendations on monitoring for adverse events. Clinical and Experimental Rheumatology. 29: S116-20. PMID 22018196  0.36
2011 Smits NA, Duru N, Bijlsma JW, Jacobs JW. Adverse events of intravenous glucocorticoid pulse therapy in inflammatory diseases: a meta-analysis. Clinical and Experimental Rheumatology. 29: S85-92. PMID 22018191  0.36
2011 Jacobs JW, Bijlsma JW. Glucocorticoids in rheumatology: indications and routes of administration. Clinical and Experimental Rheumatology. 29: S81-4. PMID 22018190  0.36
2011 Jacobs JW, Bijlsma JW. Glucocorticoids in rheumatoid arthritis: lessons from the Utrecht study. Clinical and Experimental Rheumatology. 29: S59-62. PMID 22018185  0.36
2011 Hoes JN, van der Goes MC, van Raalte DH, van der Zijl NJ, den Uyl D, Lems WF, Lafeber FP, Jacobs JW, Welsing PM, Diamant M, Bijlsma JW. Glucose tolerance, insulin sensitivity and β-cell function in patients with rheumatoid arthritis treated with or without low-to-medium dose glucocorticoids. Annals of the Rheumatic Diseases. 70: 1887-94. PMID 21908880 DOI: 10.1136/ard.2011.151464  0.36
2011 Hoes JN, Van der Goes MC, Jacobs JW, Lafeber FP, Bijlsma JW, Van Roon JA. Changes in macrophage inhibitory factor correlate with changes in bone mineral density in glucocorticoid-treated patients with rheumatoid arthritis. Rheumatology (Oxford, England). 50: 1921-4. PMID 21852299 DOI: 10.1093/rheumatology/ker268  0.36
2011 Bakker MF, Verstappen SM, Welsing PM, Jacobs JW, Jahangier ZN, van der Veen MJ, Bijlsma JW, Lafeber FP. The relation between cartilage biomarkers (C2C, C1,2C, CS846, and CPII) and the long-term outcome of rheumatoid arthritis patients within the CAMERA trial. Arthritis Research & Therapy. 13: R70. PMID 21539729 DOI: 10.1186/ar3331  0.36
2011 Hoes JN, Jacobs JW, Bijlsma JW. Glucocorticoids are forever? Rheumatology (Oxford, England). 50: 1940-1. PMID 21489972 DOI: 10.1093/rheumatology/ker141  0.36
2011 Bakker MF, Jacobs JW, Welsing PM, Vreugdenhil SA, van Booma-Frankfort C, Linn-Rasker SP, Ton E, Lafeber FP, Bijlsma JW. Early clinical response to treatment predicts 5-year outcome in RA patients: follow-up results from the CAMERA study. Annals of the Rheumatic Diseases. 70: 1099-103. PMID 21406458 DOI: 10.1136/ard.2010.137943  0.36
2011 van der Goes MC, Bossema ER, Hartkamp A, Godaert GL, Jacobs JW, Kruize AA, Derksen RH, Bijlsma JW, Geenen R. Cortisol during the day in patients with systemic lupus erythematosus or primary Sjogren's syndrome. The Journal of Rheumatology. 38: 285-8. PMID 21159832 DOI: 10.3899/jrheum.100572  0.36
2011 Jahangier ZN, Jacobs JW, Swen WA, Moolenburgh JD, Bruyn GA, Griep EN, Bijlsma JW. Can simple ultrasonography predict the clinical effect of intra-articular injection therapy of the knee joint? Clinical Rheumatology. 30: 749-55. PMID 21080021 DOI: 10.1007/s10067-010-1614-0  0.36
2010 Hoes JN, Jacobs JW, Buttgereit F, Bijlsma JW. Current view of glucocorticoid co-therapy with DMARDs in rheumatoid arthritis. Nature Reviews. Rheumatology. 6: 693-702. PMID 21119718 DOI: 10.1038/nrrheum.2010.179  0.36
2010 van der Goes MC, Jacobs JW, Boers M, Andrews T, Blom-Bakkers MA, Buttgereit F, Caeyers N, Cutolo M, Da Silva JA, Guillevin L, Kirwan JR, Rovensky J, Severijns G, Webber S, Westhovens R, et al. Monitoring adverse events of low-dose glucocorticoid therapy: EULAR recommendations for clinical trials and daily practice. Annals of the Rheumatic Diseases. 69: 1913-9. PMID 20693273 DOI: 10.1136/ard.2009.124958  0.36
2010 Jacobs JW, Bijlsma JW. Modified release prednisone in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases. 69: 1257-9. PMID 20525834 DOI: 10.1136/ard.2010.132738  0.36
2010 Hoes JN, Jacobs JW, Hulsmans HM, De Nijs RN, Lems WF, Bruyn GA, Geusens PP, Bijlsma JW. High incidence rate of vertebral fractures during chronic prednisone treatment, in spite of bisphosphonate or alfacalcidol use. Extension of the alendronate or alfacalcidol in glucocorticoid-induced osteoporosis-trial. Clinical and Experimental Rheumatology. 28: 354-9. PMID 20406615  0.36
2010 Bijlsma JW, van der Goes MC, Hoes JN, Jacobs JW, Buttgereit F, Kirwan J. Low-dose glucocorticoid therapy in rheumatoid arthritis: an obligatory therapy. Annals of the New York Academy of Sciences. 1193: 123-6. PMID 20398017 DOI: 10.1111/j.1749-6632.2009.05342.x  0.36
2010 Jacobs JW, Da Silva JA, Armbrecht G, Bijlsma JW, Verstappen SM. Prediction of vertebral fractures is specific for gender and site of bone mineral density measurement. The Journal of Rheumatology. 37: 149-54. PMID 19918046 DOI: 10.3899/jrheum.090731  0.36
2010 van der Goes MC, Jacobs JW, Boers M, Andrews T, Blom-Bakkers MA, Buttgereit F, Caeyers N, Choy EH, Cutolo M, Da Silva JA, Guillevin L, Holland M, Kirwan JR, Rovensky J, Saag KG, et al. Patient and rheumatologist perspectives on glucocorticoids: an exercise to improve the implementation of the European League Against Rheumatism (EULAR) recommendations on the management of systemic glucocorticoid therapy in rheumatic diseases. Annals of the Rheumatic Diseases. 69: 1015-21. PMID 19762359 DOI: 10.1136/ard.2009.114579  0.36
2010 Arbitrario JP, Belmont BJ, Evanchik MJ, Flanagan WM, Fucini RV, Hansen SK, Harris SO, Hashash A, Hoch U, Hogan JN, Howlett AR, Jacobs JW, Lam JW, Ritchie SC, Romanowski MJ, et al. SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo. Cancer Chemotherapy and Pharmacology. 65: 707-17. PMID 19649632 DOI: 10.1007/s00280-009-1076-8  0.32
2010 Verstappen SM, Bakker MF, Heurkens AH, van der Veen MJ, Kruize AA, Geurts MA, Bijlsma JW, Jacobs JW. Adverse events and factors associated with toxicity in patients with early rheumatoid arthritis treated with methotrexate tight control therapy: the CAMERA study. Annals of the Rheumatic Diseases. 69: 1044-8. PMID 19581281 DOI: 10.1136/ard.2008.106617  0.36
2009 Jacobs JW, Bijlsma JW. [Methotrexate: mainstay of rheumatoid arthritis treatment]. Nederlands Tijdschrift Voor Geneeskunde. 153: A879. PMID 19785862  0.36
2009 Jacobs JW, Huizinga TW, Bijlsma JW, van der Helm-van Mil AH. [Progress due to genetic research on rheumatoid arthritis: hype or hope?]. Nederlands Tijdschrift Voor Geneeskunde. 153: A206. PMID 19785838  0.36
2009 Jacobs JW, Bijlsma JW. [Insufficient evidence for oral glucocorticoids as first-line therapy for acute gout]. Nederlands Tijdschrift Voor Geneeskunde. 153: A615. PMID 19785794  0.36
2009 Zhong M, Bui M, Shen W, Baskaran S, Allen DA, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris SO, Heumann SA, Hoch U, Ivy SN, Jacobs JW, Lam S, et al. 2-Aminobenzimidazoles as potent Aurora kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 5158-61. PMID 19646866 DOI: 10.1016/j.bmcl.2009.07.016  0.32
2009 Bijlsma JW, Jacobs JW. Methotrexate: still the anchor drug in RA treatment. Joint, Bone, Spine : Revue Du Rhumatisme. 76: 452-4. PMID 19560956 DOI: 10.1016/j.jbspin.2009.05.007  0.36
2009 van der Zant FM, Boer RO, Moolenburgh JD, Jahangier ZN, Bijlsma JW, Jacobs JW. Radiation synovectomy with (90)Yttrium, (186)Rhenium and (169)Erbium: a systematic literature review with meta-analyses. Clinical and Experimental Rheumatology. 27: 130-9. PMID 19327243  0.36
2009 Jacobs JW, Bijlsma JW. Innovative combination strategy to enhance effect and diminish adverse effects of glucocorticoids: another promise? Arthritis Research & Therapy. 11: 105. PMID 19291268 DOI: 10.1186/ar2615  0.36
2009 Yang W, Fucini RV, Fahr BT, Randal M, Lind KE, Lam MB, Lu W, Lu Y, Cary DR, Romanowski MJ, Colussi D, Pietrak B, Allison TJ, Munshi SK, Penny DM, ... ... Jacobs JW, et al. Fragment-based discovery of nonpeptidic BACE-1 inhibitors using tethering. Biochemistry. 48: 4488-96. PMID 19284778 DOI: 10.1021/bi900017q  0.32
2009 Oslob JD, Heumann SA, Yu CH, Allen DA, Baskaran S, Bui M, Delarosa E, Fung AD, Hashash A, Hau J, Ivy S, Jacobs JW, Lew W, Maung J, McDowell RS, et al. Water-soluble prodrugs of an Aurora kinase inhibitor. Bioorganic & Medicinal Chemistry Letters. 19: 1409-12. PMID 19186057 DOI: 10.1016/j.bmcl.2009.01.043  0.32
2009 Hoes JN, Jacobs JW, Verstappen SM, Bijlsma JW, Van der Heijden GJ. Adverse events of low- to medium-dose oral glucocorticoids in inflammatory diseases: a meta-analysis. Annals of the Rheumatic Diseases. 68: 1833-8. PMID 19066177 DOI: 10.1136/ard.2008.100008  0.36
2008 Oslob JD, Romanowski MJ, Allen DA, Baskaran S, Bui M, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris S, Heumann SA, Hoch U, Jacobs JW, Lam J, Lawrence CE, et al. Discovery of a potent and selective aurora kinase inhibitor. Bioorganic & Medicinal Chemistry Letters. 18: 4880-4. PMID 18678489 DOI: 10.1016/j.bmcl.2008.07.073  0.32
2008 Jacobs JW, Bijlsma JW. [The anticitrulline antibody test: unsuitable for screening for rheumatoid arthritis]. Nederlands Tijdschrift Voor Geneeskunde. 152: 69-70. PMID 18265793  0.36
2008 Bijlsma JW, Jacobs JW. Glucocorticoid chronotherapy in rheumatoid arthritis. Lancet (London, England). 371: 183-4. PMID 18207003 DOI: 10.1016/S0140-6736(08)60114-2  0.36
2007 Bakker MF, Jacobs JW, Verstappen SM, Bijlsma JW. Tight control in the treatment of rheumatoid arthritis: efficacy and feasibility. Annals of the Rheumatic Diseases. 66: iii56-60. PMID 17934098 DOI: 10.1136/ard.2007.078360  0.36
2007 Verstappen SM, Jacobs JW, Huisman AM, van Rijthoven AW, Sokka T, Bijlsma JW. Functional Health Assessment Questionnaire (HAQ) and Psychological HAQ Are Associated with and Predicted by Different Factors in Rheumatoid Arthritis. The Journal of Rheumatology. 34: 1837-40. PMID 17787050  0.36
1993 Cho CY, Moran EJ, Cherry SR, Stephans JC, Fodor SPA, Adams CL, Sundaram A, Jacobs JW, Schultz PG. An unnatural biopolymer Science. 261: 1303-1305. PMID 7689747  0.32
1986 Pollack SJ, Jacobs JW, Schultz PG. Selective chemical catalysis by an antibody. Science (New York, N.Y.). 234: 1570-3. PMID 3787262  0.6
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