| Year |
Citation |
Score |
| 2024 |
Gui F, Jiang B, Jiang J, He Z, Tsujino T, Takai T, Arai S, Pana C, Köllermann J, Bradshaw GA, Eisert R, Kalocsay M, Fassl A, Balk SP, Kibel AS, et al. Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer. Biorxiv : the Preprint Server For Biology. PMID 39026842 DOI: 10.1101/2024.07.09.602803 |
0.727 |
|
| 2024 |
Ji W, Du G, Jiang J, Lu W, Mills CE, Yuan L, Jiang F, He Z, Bradshaw GA, Chung M, Jiang Z, Byun WS, Hinshaw SM, Zhang T, Gray NS. Discovery of bivalent small molecule degraders of cyclin-dependent kinase 7 (CDK7). European Journal of Medicinal Chemistry. 276: 116613. PMID 39004018 DOI: 10.1016/j.ejmech.2024.116613 |
0.552 |
|
| 2024 |
Li Z, Jiang J, Ficarro SB, Beyett TS, To C, Tavares I, Zhu Y, Li J, Eck MJ, Jänne PA, Marto JA, Zhang T, Che J, Gray NS. Molecular Bidents with Two Electrophilic Warheads as a New Pharmacological Modality. Acs Central Science. 10: 1156-1166. PMID 38947214 DOI: 10.1021/acscentsci.3c01245 |
0.498 |
|
| 2024 |
Li Z, Lu W, Beyett TS, Ficarro SB, Jiang J, Tse J, Kim AY, Marto JA, Che J, Jänne PA, Eck MJ, Zhang T, Gray NS. ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. Journal of Medicinal Chemistry. PMID 38300264 DOI: 10.1021/acs.jmedchem.3c01891 |
0.424 |
|
| 2023 |
Li Y, Jiang J, Wang X, Cao Y, Tang L, Song X, Huang F, Li M, Chen F, Wan H, Ye S. Engrailed 2 serves as a master regulator of the super-enhancer in the TNC gene locus in non-small cell lung cancer. Environmental Toxicology. PMID 37987507 DOI: 10.1002/tox.24047 |
0.302 |
|
| 2023 |
Zhao S, Li Y, Li G, Ye J, Wang R, Zhang X, Li F, Gao C, Li J, Jiang J, Mi Y. PI3K/mTOR inhibitor VS-5584 combined with PLK1 inhibitor exhibits synergistic anti-cancer effects on non-small cell lung cancer. European Journal of Pharmacology. 176004. PMID 37625683 DOI: 10.1016/j.ejphar.2023.176004 |
0.349 |
|
| 2023 |
Liu Y, Guo Z, Lang F, Li J, Jiang J. Anticancer Effect of Active Component of Astragalus Membranaceus Combined with Olaparib on Ovarian Cancer Predicted by Network-Based Pharmacology. Applied Biochemistry and Biotechnology. PMID 36976504 DOI: 10.1007/s12010-023-04462-5 |
0.336 |
|
| 2023 |
Teng M, Jiang J, Wang ES, Geng Q, Toenjes ST, Donovan KA, Mageed N, Yue H, Nowak RP, Wang J, Manz TD, Fischer ES, Cantley LC, Gray NS. Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader. Angewandte Chemie (International Ed. in English). e202302364. PMID 36898968 DOI: 10.1002/anie.202302364 |
0.471 |
|
| 2023 |
Wang R, Hou Y, Geng G, Zhu X, Wang Z, Cai W, Ye J, Zhao S, Mi Y, Jiang J. Onvansertib inhibits the proliferation and improves the cisplatin-resistance of lung adenocarcinoma via β-catenin/c-Myc signaling pathway. American Journal of Cancer Research. 13: 623-637. PMID 36895968 |
0.307 |
|
| 2022 |
Ji W, Wang ES, Manz TD, Jiang J, Donovan KA, Abulaiti X, Fischer ES, Cantley LC, Zhang T, Gray NS. Development of potent and selective degraders of PI5P4Kγ. European Journal of Medicinal Chemistry. 247: 115027. PMID 36584631 DOI: 10.1016/j.ejmech.2022.115027 |
0.505 |
|
| 2022 |
Fan M, Lu W, Che J, Kwiatkowski NP, Gao Y, Seo HS, Ficarro SB, Gokhale PC, Liu Y, Geffken EA, Lakhani J, Song K, Kuljanin M, Ji W, Jiang J, et al. Covalent disruptor of YAP-TEAD association suppresses defective hippo signaling. Elife. 11. PMID 36300789 DOI: 10.7554/eLife.78810 |
0.735 |
|
| 2022 |
Du G, Jiang J, Henning NJ, Safaee N, Koide E, Nowak RP, Donovan KA, Yoon H, You I, Yue H, Eleuteri NA, He Z, Li Z, Huang HT, Che J, et al. Exploring the target scope of KEAP1 E3 ligase-based PROTACs. Cell Chemical Biology. PMID 36070758 DOI: 10.1016/j.chembiol.2022.08.003 |
0.688 |
|
| 2022 |
Li Z, Ishida R, Liu Y, Wang J, Li Y, Gao Y, Jiang J, Che J, Sheltzer JM, Robers MB, Zhang T, Westover KD, Nabet B, Gray NS. Synthesis and Structure-Activity relationships of cyclin-dependent kinase 11 inhibitors based on a diaminothiazole scaffold. European Journal of Medicinal Chemistry. 238: 114433. PMID 35597007 DOI: 10.1016/j.ejmech.2022.114433 |
0.548 |
|
| 2022 |
Powell CE, Hatcher JM, Jiang J, Vatsan PS, Che J, Gray NS. Selective Macrocyclic Inhibitors of DYRK1A/B. Acs Medicinal Chemistry Letters. 13: 577-585. PMID 35450378 DOI: 10.1021/acsmedchemlett.1c00630 |
0.529 |
|
| 2021 |
Lu Y, Fan Z, Zhu SJ, Huang X, Zhuang Z, Li Y, Deng Z, Gao L, Hong X, Zhang T, Li L, Sun X, Huang W, Zhang J, Liu Y, ... ... Jiang J, et al. A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC. Embo Molecular Medicine. e14296. PMID 34845836 DOI: 10.15252/emmm.202114296 |
0.737 |
|
| 2021 |
Hatcher JM, Vatsan PS, Wang E, Jiang J, Gray NS. Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19. Acs Medicinal Chemistry Letters. 12: 1689-1693. PMID 34795857 DOI: 10.1021/acsmedchemlett.1c00300 |
0.49 |
|
| 2021 |
Teng M, Jiang J, Ficarro SB, Seo HS, Bae JH, Donovan KA, Fischer ES, Zhang T, Dhe-Paganon S, Marto JA, Gray NS. Exploring Ligand-Directed -Acyl--alkylsulfonamide-Based Acylation Chemistry for Potential Targeted Degrader Development. Acs Medicinal Chemistry Letters. 12: 1302-1307. PMID 34413960 DOI: 10.1021/acsmedchemlett.1c00285 |
0.418 |
|
| 2021 |
Jiang B, Jiang J, Kaltheuner IH, Iniguez AB, Anand K, Ferguson FM, Ficarro SB, Seong BKA, Greifenberg AK, Dust S, Kwiatkowski NP, Marto JA, Stegmaier K, Zhang T, Geyer M, et al. Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma. European Journal of Medicinal Chemistry. 221: 113481. PMID 33945934 DOI: 10.1016/j.ejmech.2021.113481 |
0.531 |
|
| 2021 |
Du G, Jiang J, Wu Q, Henning NJ, Donovan KA, Yue H, Che J, Lu W, Fischer ES, Bardeesy N, Zhang T, Gray NS. Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2. Angewandte Chemie (International Ed. in English). PMID 33915015 DOI: 10.1002/anie.202101328 |
0.506 |
|
| 2021 |
Jiang B, Gao Y, Che J, Lu W, Kaltheuner IH, Dries R, Kalocsay M, Berberich MJ, Jiang J, You I, Kwiatkowski N, Riching KM, Daniels DL, Sorger PK, Geyer M, et al. Discovery and resistance mechanism of a selective CDK12 degrader. Nature Chemical Biology. PMID 33753926 DOI: 10.1038/s41589-021-00765-y |
0.528 |
|
| 2020 |
Jiang J, Jiang B, He Z, Ficarro SB, Che J, Marto JA, Gao Y, Zhang T, Gray NS. Discovery of Covalent MKK4/7 Dual Inhibitor. Cell Chemical Biology. PMID 32916088 DOI: 10.1016/J.Chembiol.2020.08.014 |
0.759 |
|
| 2020 |
Gray NS, Teng M, Jiang J, He Z, Kwiatkowski NP, Donovan KA, Mills CE, Victor C, Hatcher JM, Fischer ES, Sorger PK, Zhang T. Development of CDK2 and CDK5 Dual Degrader TMX-2172. Angewandte Chemie (International Ed. in English). PMID 32415712 DOI: 10.1002/Anie.202004087 |
0.734 |
|
| 2020 |
Du G, Rao S, Gurbani D, Henning NJ, Jiang J, Che J, Yang A, Ficarro SB, Marto JA, Aguirre AJ, Sorger PK, Westover KD, Zhang T, Gray NS. Structure-based design of a potent and selective covalent inhibitor for SRC kinase that targets a p-Loop cysteine. Journal of Medicinal Chemistry. PMID 31935084 DOI: 10.1021/Acs.Jmedchem.9B01502 |
0.546 |
|
| 2019 |
Gui F, Jiang J, He Z, Li L, Li Y, Deng Z, Lu Y, Wu X, Chen G, Su J, Song S, Zhang YM, Yun CH, Huang X, Weisberg E, et al. A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant Btk mutation in B-cell malignancies. British Journal of Pharmacology. PMID 31364164 DOI: 10.1111/Bph.14809 |
0.756 |
|
| 2016 |
Jiang J, Gui F, He Z, Li L, Li Y, Li S, Wu X, Deng Z, Sun X, Huang X, Huang W, Han S, Zhang T, Wang Z, Jiao B, et al. Targeting BRK-positive breast cancers with small molecule kinase inhibitors. Cancer Research. PMID 27758886 DOI: 10.1158/0008-5472.Can-16-1038 |
0.686 |
|
| 2016 |
Zou Z, Luo X, Nie P, Wu B, Zhang T, Wei Y, Wang W, Geng G, Jiang J, Mi Y. Inhibition of SRC-3 enhances sensitivity of human cancer cells to histone deacetylase inhibitors. Biochemical and Biophysical Research Communications. PMID 27425252 DOI: 10.1016/j.bbrc.2016.07.063 |
0.339 |
|
| 2016 |
Chen Y, Jiang J, Zhao M, Luo X, Liang Z, Zhen Y, Fu Q, Deng X, Lin X, Li L, Luo R, Liu Z, Fang W. microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway. Oncotarget. PMID 27191497 DOI: 10.18632/oncotarget.9320 |
0.455 |
|
| 2015 |
Liu X, Zhao B, Zheng HJ, Hu Y, Lu G, Yang CQ, Chen JD, Chen JJ, Chen DY, Zhang L, Zhou Y, Wang LJ, Guo WZ, Bai YL, Ruan JX, ... ... Jiang JP, et al. Gossypium barbadense genome sequence provides insight into the evolution of extra-long staple fiber and specialized metabolites. Scientific Reports. 5: 14139. PMID 26420475 DOI: 10.1038/Srep14139 |
0.412 |
|
| 2015 |
Xu X, Chen L, Xu B, Xie Q, Sun M, Deng X, Wu C, Jiang J. Increased MT2-MMP expression in gastric cancer patients is associated with poor prognosis. International Journal of Clinical and Experimental Pathology. 8: 1985-90. PMID 25973093 |
0.425 |
|
| 2015 |
Deng X, Wang S, Liang X, Jiang J, Wang B, Deng L. The complete mitochondrial genome of Kaloula rugifera (Amphibia, Anura, Microhylidae). Mitochondrial Dna. 1-2. PMID 25959137 DOI: 10.3109/19401736.2015.1018235 |
0.402 |
|
| 2015 |
Jiang J, Gu J, Zhang L, Zhang C, Deng X, Dou T, Zhao G, Zhou Y. Comparing Mycobacterium tuberculosis genomes using genome topology networks. Bmc Genomics. 16: 85. PMID 25766780 DOI: 10.1186/S12864-015-1259-0 |
0.407 |
|
| 2015 |
Lu W, Cheng F, Jiang J, Zhang C, Deng X, Xu Z, Zou S, Shen X, Tang Y, Huang J. FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach. Scientific Reports. 5: 8114. PMID 25631039 DOI: 10.1038/srep08114 |
0.461 |
|
| 2014 |
Guo K, Fang T, Wang J, Wu AA, Wang Y, Jiang J, Wu X, Song S, Su W, Xu Q, Deng X. Two new spirooxindole alkaloids from rhizosphere strain Streptomyces sp. xzqh-9. Bioorganic & Medicinal Chemistry Letters. 24: 4995-8. PMID 25278238 DOI: 10.1016/J.Bmcl.2014.09.026 |
0.531 |
|
| 2014 |
Deng X, Zhao X, Lan Z, Jiang J, Yin W, Chen L. Anti-tumor effects of flavonoids from the ethnic medicine Docynia delavayi (Franch.) Schneid. and its possible mechanism Journal of Medicinal Food. 17: 787-794. PMID 24940817 DOI: 10.1089/jmf.2013.2886 |
0.486 |
|
| 2014 |
Deng X, Tang H, Jiang J. Recent progress in graphene-material-based optical sensors. Analytical and Bioanalytical Chemistry. 406: 6903-16. PMID 24880874 DOI: 10.1007/s00216-014-7895-4 |
0.385 |
|
| 2013 |
Deng XR, Liu ZX, Liu F, Pan L, Yu HP, Jiang JP, Zhang JJ, Liu L, Yu J. Holotransferrin enhances selective anticancer activity of artemisinin against human hepatocellular carcinoma cells. Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 33: 862-5. PMID 24337849 DOI: 10.1007/s11596-013-1212-x |
0.539 |
|
| 2013 |
Wang Y, Deng X, Liu J, Tang H, Jiang J. Surface enhanced Raman scattering based sensitive detection of histone demethylase activity using a formaldehyde-selective reactive probe. Chemical Communications (Cambridge, England). 49: 8489-91. PMID 23938472 DOI: 10.1039/c3cc44243h |
0.422 |
|
| 2012 |
Li L, Gu W, Du J, Reid B, Deng X, Liu Z, Zong Z, Wang H, Yao B, Yang C, Yan J, Zeng L, Chalmers L, Zhao M, Jiang J. Electric fields guide migration of epidermal stem cells and promote skin wound healing. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 20: 840-51. PMID 23082865 DOI: 10.1111/j.1524-475X.2012.00829.x |
0.491 |
|
| 2012 |
Deng XC, Li SR, Zhang Q, Zhou CJ, Yang QF, Jiang J, Kong BH. [Analysis of the status of DACH1 gene promoter methylation in endometrial carcinoma and its clinical significance]. Zhonghua Fu Chan Ke Za Zhi. 47: 263-7. PMID 22781112 |
0.413 |
|
| 2011 |
Yin K, Deng X, Mo ZC, Zhao GJ, Jiang J, Cui LB, Tan CZ, Wen GB, Fu Y, Tang CK. Tristetraprolin-dependent post-transcriptional regulation of inflammatory cytokine mRNA expression by apolipoprotein A-I: role of ATP-binding membrane cassette transporter A1 and signal transducer and activator of transcription 3. The Journal of Biological Chemistry. 286: 13834-45. PMID 21339300 DOI: 10.1074/Jbc.M110.202275 |
0.431 |
|
| 2008 |
Li X, Wang X, He K, Ma Y, Su N, He H, Stolc V, Tongprasit W, Jin W, Jiang J, Terzaghi W, Li S, Deng XW. High-resolution mapping of epigenetic modifications of the rice genome uncovers interplay between DNA methylation, histone methylation, and gene expression. The Plant Cell. 20: 259-76. PMID 18263775 DOI: 10.1105/Tpc.107.056879 |
0.419 |
|
| 2005 |
Deng XL, Wu XB, Jiang J, Guo YH, Yan H, Shi B, Chen M, Yang Y, Wang JC, Wang XY, Qiu JX, Gao L, Gao W. [Recombinant adeno-associated viral vector 2-mediated gene transfer of VEGF165 improved porcine chronic myocardial ischemia]. Zhonghua Xin Xue Guan Bing Za Zhi. 33: 732-7. PMID 16188064 |
0.4 |
|
| 2005 |
Deng XH, Zhai JY, Jiang J, Li F, Pei X, Wang HT. [A clinical study of presurgical nasoalveolar molding in infants with complete cleft lip and palate]. Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology. 40: 144-6. PMID 15842873 |
0.392 |
|
| 2005 |
Deng X, Li QB, Lu YH, He N, Jiang J. Genetic engineering of E-coli SE5000 and its potential for Ni2+ bioremediation Process Biochemistry. 40: 425-430. DOI: 10.1016/J.Procbio.2004.01.019 |
0.466 |
|
| 2002 |
Deng X, Cheng N, Wang H, Zhai J, Cui Y, Deng H, Pei X, Jiang J, Li F. [Simultaneous repair of complete cleft lip and palatein infancy-preliminary observation (271 cases report)]. Zhonghua Zheng Xing Wai Ke Za Zhi = Zhonghua Zhengxing Waike Zazhi = Chinese Journal of Plastic Surgery. 18: 211-3. PMID 12382570 |
0.394 |
|
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