Eric J. Toone - Publications

Chemistry Duke University, Durham, NC 
biocatalysis/applied enzymology, ligand binding and the activity of water, and the synthesis of novel donors of nitric oxide

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Year Citation  Score
2015 King JR, Bowers CM, Toone EJ. Specific binding at the cellulose binding module-cellulose interface observed by force spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 3431-40. PMID 25738531 DOI: 10.1021/la504836u  1
2014 Xia W, Gooden D, Liu L, Zhao S, Soderblom EJ, Toone EJ, Beyer WF, Walder H, Spector NL. Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis. Plos One. 9: e88983. PMID 24551203 DOI: 10.1371/journal.pone.0088983  1
2014 Lee CJ, Liang X, Gopalaswamy R, Najeeb J, Ark ED, Toone EJ, Zhou P. Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC. Acs Chemical Biology. 9: 237-46. PMID 24117400 DOI: 10.1021/cb400067g  1
2014 Sund JB, Causey CP, Wolter SD, Parker CB, Stoner BR, Toone EJ, Glass JT. Diamond surface functionalization with biomimicry - Amine surface tether and thiol moiety for electrochemical sensors Applied Surface Science. 301: 293-299. DOI: 10.1016/j.apsusc.2014.02.067  1
2014 Bowers CM, Zhang M, Lyubarskaya Y, Toone EJ, Tang C, Shestopalov AA. Structural Modifications in Bilayered Molecular Systems Lead to Predictable Changes in Their Electronic Properties Advanced Materials Interfaces. 1. DOI: 10.1002/admi.201300109  1
2013 Liang X, Lee CJ, Zhao J, Toone EJ, Zhou P. Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors. Journal of Medicinal Chemistry. 56: 6954-66. PMID 23914798 DOI: 10.1021/jm4007774  1
2013 Toone E, De Winde H. Energy biotechnology in 2013: Advanced technology development for breakthroughs in fuels and chemicals production Current Opinion in Biotechnology. 24: 367-368. PMID 23692669 DOI: 10.1016/j.copbio.2013.04.009  1
2013 Bowers CM, Carlson DA, Rivera M, Clark RL, Toone EJ. Effect of compressive force on unbinding specific protein-ligand complexes with force spectroscopy. The Journal of Physical Chemistry. B. 117: 4755-62. PMID 23537272 DOI: 10.1021/jp309393s  1
2013 Wang Y, King JR, Wu P, Pelzman DL, Beratan DN, Toone EJ. Enthalpic signature of methonium desolvation revealed in a synthetic host-guest system based on cucurbit[7]uril. Journal of the American Chemical Society. 135: 6084-91. PMID 23510488 DOI: 10.1021/ja311327v  1
2012 Wilfong EM, Du Y, Toone EJ. An enthalpic basis of additivity in biphenyl hydroxamic acid ligands for stromelysin-1. Bioorganic & Medicinal Chemistry Letters. 22: 6521-4. PMID 22985855 DOI: 10.1016/j.bmcl.2012.05.032  1
2012 Bowers CM, Shestopalov AA, Clark RL, Toone EJ. Multicomponent patterning of indium tin oxide. Acs Applied Materials & Interfaces. 4: 3932-7. PMID 22834789 DOI: 10.1021/am300768f  1
2012 Bowers CM, Carlson DA, Shestopalov AA, Clark RL, Toone EJ. A general and efficient cantilever functionalization technique for AFM molecular recognition studies. Biopolymers. 97: 761-5. PMID 22806495 DOI: 10.1002/bip.22061  1
2012 Cheriyan M, Toone EJ, Fierke CA. Improving upon nature: active site remodeling produces highly efficient aldolase activity toward hydrophobic electrophilic substrates. Biochemistry. 51: 1658-68. PMID 22316217 DOI: 10.1021/bi201899b  1
2012 Yamazaki A, Li J, Zeng Q, Khokhani D, Hutchins WC, Yost AC, Biddle E, Toone EJ, Chen X, Yang CH. Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system. Antimicrobial Agents and Chemotherapy. 56: 36-43. PMID 21968370 DOI: 10.1128/AAC.00732-11  1
2012 Coombs GS, Schmitt AA, Canning CA, Alok A, Low IC, Banerjee N, Kaur S, Utomo V, Jones CM, Pervaiz S, Toone EJ, Virshup DM. Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer. Oncogene. 31: 213-25. PMID 21666721 DOI: 10.1038/onc.2011.228  1
2011 Toone EJ. Advances in enzymology and related areas of molecular biology. Preface. Advances in Enzymology and Related Areas of Molecular Biology. 78: ix-xi. PMID 22220470 DOI: 10.1002/9781118105771  1
2011 Bowers CM, Toone EJ, Clark RL, Shestopalov AA. Soft lithographic functionalization and patterning oxide-free silicon and germanium. Journal of Visualized Experiments : Jove. PMID 22214997 DOI: 10.3791/3478  1
2011 Lund LN, Christensen T, Toone E, Houen G, Staby A, St. Hilaire PM. Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry Journal of Molecular Recognition. 24: 945-952. PMID 22038801 DOI: 10.1002/jmr.1140  1
2011 Cheriyan M, Walters MJ, Kang BD, Anzaldi LL, Toone EJ, Fierke CA. Directed evolution of a pyruvate aldolase to recognize a long chain acyl substrate. Bioorganic & Medicinal Chemistry. 19: 6447-53. PMID 21944547 DOI: 10.1016/j.bmc.2011.08.056  1
2011 Wilfong EM, Kogiso Y, Muthukrishnan S, Kowatz T, Du Y, Bowie A, Naismith JH, Hadad CM, Toone EJ, Gustafson TL. A multidisciplinary approach to probing enthalpy-entropy compensation and the interfacial mobility model. Journal of the American Chemical Society. 133: 11515-23. PMID 21692482 DOI: 10.1021/ja1098287  1
2011 Toone EJ. Bacterial infection remains a leading cause of death in both Western and developing world. Preface. Advances in Enzymology and Related Areas of Molecular Biology. 77: xi-xiii. PMID 21692365  1
2011 Nguyen BD, Cunningham D, Liang X, Chen X, Toone EJ, Raetz CR, Zhou P, Valdivia RH. Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis. Proceedings of the National Academy of Sciences of the United States of America. 108: 10284-9. PMID 21628561 DOI: 10.1073/pnas.1107478108  1
2011 Shestopalov AA, Morris CJ, Vogen BN, Hoertz A, Clark RL, Toone EJ. Soft-lithographic approach to functionalization and nanopatterning oxide-free silicon. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 6478-85. PMID 21520913 DOI: 10.1021/la200373g  1
2011 Morris CJ, Shestopalov AA, Gold BH, Clark RL, Toone EJ. Patterning NHS-terminated SAMs on germanium. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 6486-9. PMID 21504221 DOI: 10.1021/la200374k  1
2011 Liang X, Lee CJ, Chen X, Chung HS, Zeng D, Raetz CR, Li Y, Zhou P, Toone EJ. Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold. Bioorganic & Medicinal Chemistry. 19: 852-60. PMID 21194954 DOI: 10.1016/j.bmc.2010.12.017  1
2011 Lee CJ, Liang X, Chen X, Zeng D, Joo SH, Chung HS, Barb AW, Swanson SM, Nicholas RA, Li Y, Toone EJ, Raetz CR, Zhou P. Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chemistry & Biology. 18: 38-47. PMID 21167751 DOI: 10.1016/j.chembiol.2010.11.011  1
2011 Hwang S, Schmitt AA, Luteran AE, Toone EJ, McCafferty DG. Thermodynamic characterization of the binding interaction between the histone demethylase LSD1/KDM1 and CoREST. Biochemistry. 50: 546-57. PMID 21142040 DOI: 10.1021/bi101776t  1
2011 Toone EJ. Preface Advances in Enzymology and Related Areas of Molecular Biology. 78: i-xi. DOI: 10.1002/9780470920541  1
2010 Colomer J, Schmitt AA, Toone EJ, Means AR. Identification and inhibitory properties of a novel Ca(2+)/calmodulin antagonist. Biochemistry. 49: 4244-54. PMID 20392081 DOI: 10.1021/bi1001213  1
2010 Shestopalov AA, Clark RL, Toone EJ. Catalytic microcontact printing on chemically functionalized H-terminated silicon. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 1449-51. PMID 19950970 DOI: 10.1021/la903465f  1
2010 Shestopalov AA, Clark RL, Toone EJ. Inkless microcontact printing on SAMs of Boc- and TBS-protected thiols. Nano Letters. 10: 43-6. PMID 19950928 DOI: 10.1021/nl902588d  1
2010 Wilfong EM, Locklear U, Toone EJ. A single step purification for autolytic zinc proteinases. Bioorganic & Medicinal Chemistry Letters. 20: 280-2. PMID 19942433 DOI: 10.1016/j.bmcl.2009.10.114  1
2010 Rivera M, Morris C, Carlson D, Toone EJ, Cole DG, Clark RL. Minimizing tip-sample contact force in automated atomic force microscope based force spectroscopy Proceedings of the Asme International Design Engineering Technical Conferences and Computers and Information in Engineering Conference 2009, Detc2009. 6: 731-736. DOI: 10.1115/DETC2009-87378  1
2010 Walter NG. Stepping under the single molecule microscope: The faster the better Biopolymers. 93: iii-iv. DOI: 10.1002/bip.21330  1
2009 Gao W, Liu W, Mackay JA, Zalutsky MR, Toone EJ, Chilkoti A. In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics. Proceedings of the National Academy of Sciences of the United States of America. 106: 15231-6. PMID 19706892 DOI: 10.1073/pnas.0904378106  1
2009 Arnold JJ, Choksi Y, Chen X, Shimazaki A, Hatten J, Toone EJ, Epstein DL, Challa P. Eyedrops containing SA9000 prodrugs result in sustained reductions in intraocular pressure in rabbits. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 25: 179-86. PMID 19456251 DOI: 10.1089/jop.2008.0107  1
2009 Chakrapani H, Bartberger MD, Toone EJ. C-nitroso donors of nitric oxide. The Journal of Organic Chemistry. 74: 1450-3. PMID 19146387 DOI: 10.1021/jo802517t  1
2009 Williams GJ, Thorson JS. Natural product glycosyltransferases: properties and applications. Advances in Enzymology and Related Areas of Molecular Biology. 76: 55-119. PMID 18990828  1
2009 Toone EJ. Advances in enzymology and related areas of molecular biology. Preface. Advances in Enzymology and Related Areas of Molecular Biology. 76: ix-x. PMID 18990826  1
2008 Lai TS, Liu Y, Tucker T, Daniel KR, Sane DC, Toone E, Burke JR, Strittmatter WJ, Greenberg CS. Identification of chemical inhibitors to human tissue transglutaminase by screening existing drug libraries. Chemistry & Biology. 15: 969-78. PMID 18804034 DOI: 10.1016/j.chembiol.2008.07.015  1
2008 Walters MJ, Srikannathasan V, McEwan AR, Naismith JH, Fierke CA, Toone EJ. Characterization and crystal structure of Escherichia coli KDPGal aldolase. Bioorganic & Medicinal Chemistry. 16: 710-20. PMID 17981470 DOI: 10.1016/j.bmc.2007.10.043  1
2007 Cheriyan M, Toone EJ, Fierke CA. Mutagenesis of the phosphate-binding pocket of KDPG aldolase enhances selectivity for hydrophobic substrates. Protein Science : a Publication of the Protein Society. 16: 2368-77. PMID 17962400 DOI: 10.1110/ps.073042907  1
2007 Shestopalov AA, Clark RL, Toone EJ. Inkless microcontact printing on self-assembled monolayers of fmoc-protected aminothiols. Journal of the American Chemical Society. 129: 13818-9. PMID 17949005 DOI: 10.1021/ja076226k  1
2007 Snyder PW, Johannes MS, Vogen BN, Clark RL, Toone EJ. Biocatalytic microcontact printing. The Journal of Organic Chemistry. 72: 7459-61. PMID 17705546 DOI: 10.1021/jo0711541  1
2007 Walters MJ, Toone EJ. Pyruvate aldolases in chiral carbon-carbon bond formation. Nature Protocols. 2: 1825-30. PMID 17641651 DOI: 10.1038/nprot.2007.260  1
2007 Snyder PW, Lee G, Marszalek PE, Clark RL, Toone EJ. A stochastic, cantilever approach to the evaluation of solution phase thermodynamic quantities. Proceedings of the National Academy of Sciences of the United States of America. 104: 2579-84. PMID 17307881 DOI: 10.1073/pnas.0606604104  1
2007 Matsuoka K, Goshu Y, Takezawa Y, Mori T, Sakamoto JI, Yamada A, Onaga T, Koyama T, Hatano K, Snyder PW, Toone EJ, Terunuma D. Practical synthesis of fully protected globotriaose and its glycopolymers Carbohydrate Polymers. 69: 326-335. DOI: 10.1016/j.carbpol.2006.10.011  1
2006 Perry JL, Goldsmith MR, Williams TR, Radack KP, Christensen T, Gorham J, Pasquinelli MA, Toone EJ, Beratan DN, Simon JD. Binding of warfarin influences the acid-base equilibrium of H242 in sudlow site I of human serum albumin. Photochemistry and Photobiology. 82: 1365-9. PMID 16563025 DOI: 10.1562/2006-02-23-RA-811  1
2006 Fullerton SW, Griffiths JS, Merkel AB, Cheriyan M, Wymer NJ, Hutchins MJ, Fierke CA, Toone EJ, Naismith JH. Mechanism of the Class I KDPG aldolase. Bioorganic & Medicinal Chemistry. 14: 3002-10. PMID 16403639 DOI: 10.1016/j.bmc.2005.12.022  1
2005 Gooden DM, Chakrapani H, Toone EJ. C-nitroso compounds: synthesis, physicochemical properties and biological activities. Current Topics in Medicinal Chemistry. 5: 687-705. PMID 16101429 DOI: 10.2174/1568026054679353  1
2005 Zhao YL, McCarren PR, Houk KN, Choi BY, Toone EJ. Nitrosonium-catalyzed decomposition of s-nitrosothiols in solution: a theoretical and experimental study. Journal of the American Chemical Society. 127: 10917-24. PMID 16076198 DOI: 10.1021/ja050018f  1
2005 Winter-Vann AM, Baron RA, Wong W, dela Cruz J, York JD, Gooden DM, Bergo MO, Young SG, Toone EJ, Casey PJ. A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 4336-41. PMID 15784746 DOI: 10.1073/pnas.0408107102  1
2005 Pamula VK, Srinivasan V, Chakrapani H, Fair RB, Toone EJ. A droplet-based lab-on-a-chip for colorimetric detection of nitroaromatic explosives Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 722-725. DOI: 10.1109/MEMSYS.2005.1454031  1
2005 Mori T, Hatano K, Matsuoka K, Esumi Y, Toone EJ, Terunuma D. Synthesis of carbosilane dendrimers having peripheral mannose and mannobiose Tetrahedron. 61: 2751-2760. DOI: 10.1016/j.tet.2005.01.090  1
2004 Griffiths JS, Cheriyan M, Corbell JB, Pocivavsek L, Fierke CA, Toone EJ. A bacterial selection for the directed evolution of pyruvate aldolases. Bioorganic & Medicinal Chemistry. 12: 4067-74. PMID 15246084 DOI: 10.1016/j.bmc.2004.05.034  1
2003 Christensen T, Toone EJ. Calorimetric evaluation of protein-carbohydrate affinities. Methods in Enzymology. 362: 486-504. PMID 12968383 DOI: 10.1016/S0076-6879(03)01032-2  1
2003 Debenham SD, Snyder PW, Toone EJ. Solid-phase synthesis for the identification of high-affinity bivalent lectin ligands. The Journal of Organic Chemistry. 68: 5805-11. PMID 12868911 DOI: 10.1021/jo0207271  1
2003 Christensen T, Gooden DM, Kung JE, Toone EJ. Additivity and the physical basis of multivalency effects: a thermodynamic investigation of the calcium EDTA interaction. Journal of the American Chemical Society. 125: 7357-66. PMID 12797810 DOI: 10.1021/ja021240c  1
2003 Houk KN, Hietbrink BN, Bartberger MD, McCarren PR, Choi BY, Voyksner RD, Stamler JS, Toone EJ. Nitroxyl disulfides, novel intermediates in transnitrosation reactions. Journal of the American Chemical Society. 125: 6972-6. PMID 12783550 DOI: 10.1021/ja029655l  1
2003 Perry JL, Christensen T, Goldsmith MR, Toone EJ, Beratan DN, Simon JD. Binding of ochratoxin a to human serum albumin stabilized by a protein-ligand ion pair Journal of Physical Chemistry B. 107: 7884-7888.  1
2002 Stamler JS, Toone EJ. The decomposition of thionitrites. Current Opinion in Chemical Biology. 6: 779-85. PMID 12470731 DOI: 10.1016/S1367-5931(02)00383-6  1
2002 Lundquist JJ, Toone EJ. The cluster glycoside effect. Chemical Reviews. 102: 555-78. PMID 11841254 DOI: 10.1021/cr000418f  1
2002 Griffiths JS, Wymer NJ, Njolito E, Niranjanakumari S, Fierke CA, Toone EJ. Cloning, isolation and characterization of the Thermotoga maritima KDPG aldolase. Bioorganic & Medicinal Chemistry. 10: 545-50. PMID 11814840 DOI: 10.1016/S0968-0896(01)00307-8  1
2002 Lundquist JJ, Kiburz BM, Wu JK, Gibbs KD, Toone EJ. Towards high affinity carbohydrate-binding proteins: Directed evolution of murine galectin-3 Canadian Journal of Chemistry. 80: 999-1009. DOI: 10.1139/v02-086  1
2002 Choi BY, Voyksner RD, Toone EJ. Analysis of S-nitrosothiol decomposition Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 799-800.  1
2001 Bartberger MD, Mannion JD, Powell SC, Stamler JS, Houk KN, Toone EJ. S-N dissociation energies of S-nitrosothiols: on the origins of nitrosothiol decomposition rates. Journal of the American Chemical Society. 123: 8868-9. PMID 11535101 DOI: 10.1021/ja0109390  1
2001 Wymer N, Buchanan LV, Henderson D, Mehta N, Botting CH, Pocivavsek L, Fierke CA, Toone EJ, Naismith JH. Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Structure (London, England : 1993). 9: 1-9. PMID 11342129 DOI: 10.1016/S0969-2126(00)00555-4  1
2001 DiTusa CA, McCall KA, Christensen T, Mahapatro M, Fierke CA, Toone EJ. Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants. Biochemistry. 40: 5345-51. PMID 11330997 DOI: 10.1021/bi0017327  1
2001 DiTusa CA, Christensen T, McCall KA, Fierke CA, Toone EJ. Thermodynamics of metal ion binding. 1. Metal ion binding by wild-type carbonic anhydrase. Biochemistry. 40: 5338-44. PMID 11330996 DOI: 10.1021/bi001731e  1
2001 Moya MP, Gow AJ, McMahon TJ, Toone EJ, Cheifetz IM, Goldberg RN, Stamler JS. S-nitrosothiol repletion by an inhaled gas regulates pulmonary function. Proceedings of the National Academy of Sciences of the United States of America. 98: 5792-7. PMID 11320213 DOI: 10.1073/pnas.091109498  1
2000 Trzaska SM, Toone EJ, Crumbliss AL. Microcalorimetric determination of thermodynamic parameters for ionophore-siderophore host-guest complex formation. Inorganic Chemistry. 39: 1071-5. PMID 12526393 DOI: 10.1021/ic9908571  1
2000 Lundquist JJ, Debenham SD, Toone EJ. Multivalency effects in protein--carbohydrate interaction: the binding of the Shiga-like toxin 1 binding subunit to multivalent C-linked glycopeptides. The Journal of Organic Chemistry. 65: 8245-50. PMID 11101380 DOI: 10.1021/jo000943e  1
2000 Wymer N, Toone EJ. Enzyme-catalyzed synthesis of carbohydrates. Current Opinion in Chemical Biology. 4: 110-9. PMID 10679369 DOI: 10.1016/S1367-5931(99)00061-7  1
2000 Bartberger MD, Houk KN, Powell SC, Mannion JD, Lo KY, Stamler JS, Toone EJ. Theory, spectroscopy, and crystallographic analysis of S-nitrosothiols: Conformational distribution dictates spectroscopic behavior [7] Journal of the American Chemical Society. 122: 5889-5890. DOI: 10.1021/ja994476y  1
2000 Corbell JB, Lundquist JJ, Toone EJ. A comparison of biological and calorimetric analyses of multivalent glycodendrimer ligands for concanavalin A Tetrahedron Asymmetry. 11: 95-111. DOI: 10.1016/S0957-4166(99)00589-3  1
2000 Debenham SD, Toone EJ. Regioselective reduction of 4,6-O-benzylidenes using triethylsilane and BF3.Et2O Tetrahedron Asymmetry. 11: 385-387. DOI: 10.1016/S0957-4166(99)00584-4  1
1999 Buchanan LV, Mehta N, Pocivavsek L, Niranjanakumari S, Toone EJ, Naismith JH. Initiating a structural study of 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography. 55: 1946-8. PMID 10531504 DOI: 10.1107/S0907444999011166  1
1999 Debenham SD, Cossrow J, Toone EJ. Synthesis of α- and β-carbon-linked serine analogues of the P(k) trisaccharide Journal of Organic Chemistry. 64: 9153-9163. DOI: 10.1021/jo991096m  1
1999 Dimick SM, Powell SC, McMahon SA, Moothoo DN, Naismith JH, Toone EJ. On the meaning of affinity: Cluster glycoside effects and concanavalin A Journal of the American Chemical Society. 121: 10286-10296. DOI: 10.1021/ja991729e  1
1998 Moothoo DN, McMahon SA, Dimick SM, Toone EJ, Naismith JH. Crystallization of succinylated concanavalin A bound to a synthetic bivalent ligand and preliminary structural analysis. Acta Crystallographica. Section D, Biological Crystallography. 54: 1023-5. PMID 9757127 DOI: 10.1107/S0907444998003965  1
1998 Cotterill IC, Henderson DP, Shelton MC, Toone EJ. The synthetic utility of KDPGal aldolase Journal of Molecular Catalysis - B Enzymatic. 5: 103-111. DOI: 10.1016/S1381-1177(98)00087-3  1
1998 Cotterill IC, Shelton MC, Machemer DEW, Henderson DP, Toone EJ. Effect of phosphorylation on the reaction rate of unnatural electrophiles with 2-keto-3-deoxy-6-phosphogluconate aldolase Journal of the Chemical Society - Perkin Transactions 1. 1335-1341.  1
1998 Henderson DP, Cotterill IC, Shelton MC, Toone EJ. 2-Keto-3-deoxy-6-phosphogalactonate Aldolase as a Catalyst for Stereocontrolled Carbon-Carbon Bond Formation Journal of Organic Chemistry. 63: 906-907.  1
1997 Stamler JS, Toone EJ, Lipton SA, Sucher NJ. (S)NO signals: translocation, regulation, and a consensus motif. Neuron. 18: 691-6. PMID 9182795 DOI: 10.1016/S0896-6273(00)80310-4  1
1997 Harris SL, Craig L, Mehroke JS, Rashed M, Zwick MB, Kenar K, Toone EJ, Greenspan N, Auzanneau FI, Marino-Albernas JR, Pinto BM, Scott JK. Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. Proceedings of the National Academy of Sciences of the United States of America. 94: 2454-9. PMID 9122216 DOI: 10.1073/pnas.94.6.2454  1
1997 Debenham SD, Debenham JS, Burk MJ, Toone EJ. Synthesis of carbon-linked glycopeptides through catalytic asymmetric hydrogenation Journal of the American Chemical Society. 119: 9897-9898. DOI: 10.1021/ja971324z  1
1997 Henderson DP, Shelton MC, Cotterill IC, Toone EJ. Stereospecific Preparation of the N-Terminal Amino Acid Moiety of Nikkomycins KX and KZ via a Multiple Enzyme Synthesis Journal of Organic Chemistry. 62: 7910-7911.  1
1996 Chervenak MC, Toone EJ. Analysis of the binding specificities of oligomannoside-binding proteins using methylated monosaccharides. Bioorganic & Medicinal Chemistry. 4: 1963-77. PMID 9007280 DOI: 10.1016/S0968-0896(96)00178-2  1
1996 Gupta D, Oscarson S, Raju TS, Stanley P, Toone EJ, Brewer CF. A comparison of the fine saccharide-binding specificity of Dioclea grandiflora lectin and concanavalin A. European Journal of Biochemistry / Febs. 242: 320-6. PMID 8973650  1
1996 Clark C, Bast D, Sharp AM, St Hilaire PM, Agha R, Stein PE, Toone EJ, Read RJ, Brunton JL. Phenylalanine 30 plays an important role in receptor binding of verotoxin-1. Molecular Microbiology. 19: 891-9. PMID 8820657  1
1996 Weatherman RV, Mortell KH, Chervenak M, Kiessling LL, Toone EJ. Specificity of C-glycoside complexation by mannose/glucose specific lectins. Biochemistry. 35: 3619-24. PMID 8639514 DOI: 10.1021/bi951916z  1
1996 Shelton MC, Cotterill IC, Novak STA, Poonawala RM, Sudarshan S, Toone EJ. 2-keto-3-deoxy-6-phosphogluconate aldolases as catalysts for stereocontrolled carbon-carbon bond formation Journal of the American Chemical Society. 118: X-2125. DOI: 10.1021/ja952596+  1
1995 Chervenak MC, Toone EJ. Calorimetric analysis of the binding of lectins with overlapping carbohydrate-binding ligand specificities. Biochemistry. 34: 5685-95. PMID 7727428  1
1995 Isbister BD, St. Hilaire PM, Toone EJ. Spatial organization versus total surface area as a predictor of protein hydrophobicity. The hydrophobicity of the concanavalin A binding site Journal of the American Chemical Society. 117: 12877-12878. DOI: 10.1021/ja00156a033  1
1995 Shelton MC, Toone EJ. Differential dye-ligand chromatography as a general purification protocol for 2-keto-3-deoxy-6-phosphogluconate aldolases Tetrahedron: Asymmetry. 6: 207-211. DOI: 10.1016/0957-4166(94)00376-M  1
1994 Toone EJ. Structure and energetics of protein-carbohydrate complexes Current Opinion in Structural Biology. 4: 719-728. DOI: 10.1016/S0959-440X(94)90170-8  1
1994 Chervenak MC, Toone EJ. A direct measure of the contribution of solvent reorganization to the enthalpy of ligand binding Journal of the American Chemical Society. 116: 10533-10539.  1
1993 Williams BA, Toone EJ. Calorimetric evaluation of enzyme kinetic parameters Journal of Organic Chemistry. 58: 3507-3510.  1
1992 Williams BA, Chervenak MC, Toone EJ. Energetics of lectin-carbohydrate binding. A microcalorimetric investigation of concanavalin A-oligomannoside complexation. The Journal of Biological Chemistry. 267: 22907-11. PMID 1429640  1
1992 Allen ST, Heintzelman GR, Toone EJ. Pyruvate aldolases as reagents for stereospecific aldol condensation Journal of Organic Chemistry. 57: 426-427.  1
1991 Toone EJ, Jones JB. Enzymes in organic synthesis 50. Probing the dimensions of the large hydrophobic binding region of the active site of pig liver esterase using substituted aryl malonate substrates Tetrahedron: Asymmetry. 2: 1041-1052. DOI: 10.1016/S0957-4166(00)86155-8  1
1991 Toone EJ, Jones JB. Enzymes in organic synthesis 49. Resolutions of racemic monocyclic esters with pig liver esterase Tetrahedron: Asymmetry. 2: 207-222. DOI: 10.1016/S0957-4166(00)82360-5  1
1991 Toone EJ, Simon ES, Whitesides GM. Enzymatic synthesis of uridine 5′-diphosphoglucuronic acid on a gram scale Journal of Organic Chemistry. 56: 5603-5606.  1
1990 Toone EJ, Werth MJ, Jones JB. Active-site model for interpreting and predicting the specificity of pig liver esterase Journal of the American Chemical Society. 112: 4946-4952.  1
1990 Ozaki A, Toone EJ, Von Der Osten CH, Sinskey AJ, Whitesides GM. Overproduction and substrate specificity of a bacterial fuculose-1-phosphate aldolase: A new enzymatic catalyst for stereocontrolled aldol condensation Journal of the American Chemical Society. 112: 4970-4971.  1
1989 Simon ES, Toone EJ, Ostroff G, Bednarski MD, Whitesides GM. Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. Methods in Enzymology. 179: 275-87. PMID 2560122 DOI: 10.1016/0076-6879(89)79129-1  1
1989 Toone EJ, Simon ES, Bednarski MD, Whitesides GM. Enzyme-catalyzed synthesis of carbohydrates Tetrahedron. 45: 5365-5422. DOI: 10.1016/S0040-4020(01)89487-4  1
1987 Lemière GL, Dommisse RA, Lepoivre JA, Alderweireldt FC, Hiemstra H, Wynberg H, Jones JB, Toone EJ. Determination of the absolute configuration of six-membered-ring ketones by 13C NMR Journal of the American Chemical Society. 109: 1363-1370.  1
1987 Toone EJ, Jones JB. Enzymes in organic synthesis. 40. Evaluation of the enantioselectivity of the pig liver esterase catalyzed hydrolyses of racemic piperidine carboxylic acid esters Canadian Journal of Chemistry. 65: 2722-2726.  1
1983 Bunce NJ, Deschutter CT, Toone EJ. Photolysis of some ortho-methylated monochlorobiphenyls Journal of the Chemical Society, Perkin Transactions 2. 859-861. DOI: 10.1039/P29830000859  1
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