Ben Hutchins - Publications

Affiliations: 
2009- Scripps Research Institute 

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Dinney CP, Fisher MB, Navai N, O'Donnell MA, Cutler D, Abraham A, Young S, Hutchins B, Caceres M, Kishnani N, Sode G, Cullen C, Zhang G, Grossman HB, Kamat AM, et al. Phase I trial of intravesical recombinant adenovirus mediated interferon-α2b formulated in Syn3 for Bacillus Calmette-Guérin failures in nonmuscle invasive bladder cancer. The Journal of Urology. 190: 850-6. PMID 23507396 DOI: 10.1016/j.juro.2013.03.030  0.36
2013 Kazane SA, Axup JY, Kim CH, Ciobanu M, Wold ED, Barluenga S, Hutchins BA, Schultz PG, Winssinger N, Smider VV. Self-assembled antibody multimers through peptide nucleic acid conjugation. Journal of the American Chemical Society. 135: 340-6. PMID 23210862 DOI: 10.1021/ja309505c  0.68
2012 Axup JY, Bajjuri KM, Ritland M, Hutchins BM, Kim CH, Kazane SA, Halder R, Forsyth JS, Santidrian AF, Stafin K, Lu Y, Tran H, Seller AJ, Biroc SL, Szydlik A, et al. Synthesis of site-specific antibody-drug conjugates using unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 109: 16101-6. PMID 22988081 DOI: 10.1073/pnas.1211023109  0.68
2012 Kim CH, Axup JY, Dubrovska A, Kazane SA, Hutchins BA, Wold ED, Smider VV, Schultz PG. Synthesis of bispecific antibodies using genetically encoded unnatural amino acids. Journal of the American Chemical Society. 134: 9918-21. PMID 22642368 DOI: 10.1021/ja303904e  0.68
2012 Veneziale RW, Kishnani NS, Nelson J, Resendez JC, Frank DW, Cai XY, Xie L, Cullen C, Frugone CA, Rosenfeld C, Hubbell J, Maxwell SE, Sugarman BJ, Hutchins B, Maneval D, et al. Toxicity and exposure of an adenovirus containing human interferon alpha-2b following intracystic administration in cynomolgus monkeys. Gene Therapy. 19: 742-51. PMID 21900961 DOI: 10.1038/gt.2011.116  0.36
2011 Hutchins BM, Kazane SA, Staflin K, Forsyth JS, Felding-Habermann B, Smider VV, Schultz PG. Selective formation of covalent protein heterodimers with an unnatural amino acid. Chemistry & Biology. 18: 299-303. PMID 21439474 DOI: 10.1016/j.chembiol.2011.01.006  0.68
2011 Hutchins BM, Kazane SA, Staflin K, Forsyth JS, Felding-Habermann B, Schultz PG, Smider VV. Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids. Journal of Molecular Biology. 406: 595-603. PMID 21237172 DOI: 10.1016/j.jmb.2011.01.011  0.68
2006 McAuliffe PF, Murday ME, Efron PA, Scumpia PO, Ungaro R, Abouhamze A, Tannahill CL, Hutchins B, LaFace D, Moldawer LL. Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure Gene Therapy. 13: 276-282. PMID 16251998 DOI: 10.1038/sj.gt.3302600  0.36
2006 Atencio IA, Grace M, Bordens R, Fritz M, Horowitz JA, Hutchins B, Indelicato S, Jacobs S, Kolz K, Maneval D, Musco ML, Shinoda J, Venook A, Wen S, Warren R. Biological activities of a recombinant adenovirus p53 (SCH 58500) administered by hepatic arterial infusion in a Phase 1 colorectal cancer trial. Cancer Gene Therapy. 13: 169-81. PMID 16082381 DOI: 10.1038/sj.cgt.7700870  0.36
2005 Machemer T, Engler H, Tsai V, Lee S, Cannon-Carlson S, Voloch M, Schluep T, Ravindran S, Vellekamp G, Brin E, Cornell D, Sutjipto S, Wen SF, Horn M, Van Rooijen N, ... ... Hutchins B, et al. Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 254-63. PMID 16043097 DOI: 10.1016/j.ymthe.2005.03.007  0.36
2005 Oberholzer A, Oberholzer C, Efron PA, Scumpia PO, Uchida T, Bahjat K, Ungaro R, Tannahill CL, Murday M, Bahjat FR, Tsai V, Hutchins B, Moldawer LL, Laface D, Clare-Salzler MJ. Functional modification of dendritic cells with recombinant adenovirus encoding interleukin 10 for the treatment of sepsis. Shock (Augusta, Ga.). 23: 507-15. PMID 15897802 DOI: 10.1097/01.shk.0000163208.29655.74  0.36
2004 Oberholzer C, Oberholzer A, Tschoeke SK, Minter RM, Bahjat FR, LaFace D, Hutchins B, Moldawer LL. Influence of recombinant adenovirus on liver injury in endotoxicosis and its modulation by IL-10 expression. Journal of Endotoxin Research. 10: 393-401. PMID 15588421 DOI: 10.1179/096805104225005832  0.36
2004 Rea D, Laface D, Hutchins B, Kwappenberg K, Melief CJ, Hoeben RC, Offringa R. Recombinant adenovirus-transduced human dendritic cells engineered to secrete interleukin-10 (IL-10) suppress Th1-type responses while selectively activating IL-10-producing CD4+ T cells. Human Immunology. 65: 1344-55. PMID 15556685 DOI: 10.1016/j.humimm.2004.08.185  0.36
2003 Mirza A, Wu Q, Wang L, McClanahan T, Bishop WR, Gheyas F, Ding W, Hutchins B, Hockenberry T, Kirschmeier P, Greene JR, Liu S. Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression. Oncogene. 22: 3645-54. PMID 12789273 DOI: 10.1038/sj.onc.1206477  0.36
2002 Oberholzer A, Oberholzer C, Bahjat KS, Ungaro R, Tannahill CL, Murday M, Bahjat FR, Abouhamze Z, Tsai V, LaFace D, Hutchins B, Moldawer LL, Clare-Salzler MJ. Increased survival in sepsis by in vivo adenovirus-induced expression of IL-10 in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 3412-8. PMID 11907099  0.36
2001 Oberholzer C, Oberholzer A, Bahjat FR, Minter RM, Tannahill CL, Abouhamze A, LaFace D, Hutchins B, Clare-Salzler MJ, Moldawer LL. Targeted adenovirus-induced expression of IL-10 decreases thymic apoptosis and improves survival in murine sepsis. Proceedings of the National Academy of Sciences of the United States of America. 98: 11503-8. PMID 11553765 DOI: 10.1073/pnas.181338198  0.36
2001 Minter RM, Ferry MA, Murday ME, Tannahill CL, Bahjat FR, Oberholzer C, Oberholzer A, LaFace D, Hutchins B, Wen S, Shinoda J, Copeland EM, Moldawer LL. Adenoviral delivery of human and viral IL-10 in murine sepsis. Journal of Immunology (Baltimore, Md. : 1950). 167: 1053-9. PMID 11441115  0.36
2001 Minter RM, Ferry MA, Rectenwald JE, Bahjat FR, Oberholzer A, Oberholzer C, La Face D, Tsai V, Ahmed CM, Hutchins B, Copeland EM, Ginsberg HS, Moldawer LL. Extended lung expression and increased tissue localization of viral IL-10 with adenoviral gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 98: 277-82. PMID 11134537 DOI: 10.1073/pnas.250489297  0.36
2000 Wen SF, Xie L, Mcdonald M, Digiacomo R, Chang A, Gurnani M, Shi B, Liu S, Indelicato SR, Hutchins B, Nielsen LL. Development and validation of sensitive assays to quantitate gene expression after p53 gene therapy and paclitaxel chemotherapy using in vivo dosing in tumor xenograft models Cancer Gene Therapy. 7: 1469-1480. PMID 11129289  0.36
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