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Haiquan Mao, Ph.D. - Publications

Affiliations: 
Materials Science and Engineering Johns Hopkins University, Baltimore, MD 
Area:
Gene Delivery, Biomaterials, Tissue Engineering
Website:
http://materials.jhu.edu/index.php/people/detail/hai-quan-mao/faculty
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69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ke X, Shelton L, Hu Y, Zhu Y, Chow E, Tang H, Santos JL, Mao HQ. Surface-Functionalized PEGylated Nanoparticles Deliver Messenger RNA to Pulmonary Immune Cells. Acs Applied Materials & Interfaces. PMID 32659078 DOI: 10.1021/Acsami.0C08268  0.316
2020 Zhao Y, Liang Y, Ding S, Zhang K, Mao HQ, Yang Y. Application of conductive PPy/SF composite scaffold and electrical stimulation for neural tissue engineering. Biomaterials. 255: 120164. PMID 32554132 DOI: 10.1016/J.Biomaterials.2020.120164  0.315
2020 Sarhane KA, Qiu C, Slavin BR, Hricz N, Iglesias M, Guionneau Nv, Hanwright PJ, Mi R, Höke A, Mao H, Tuffaha SH. Abstract 114: A Novel Hydrogel-based Nanofiber Drug Delivery System For Sustained Release Of Igf-1 Nanoparticles To Improve Functional Outcomes After Nerve Repair Plastic and Reconstructive Surgery. Global Open. 8: 75-76. DOI: 10.1097/01.Gox.0000667512.45496.83  0.321
2019 He Z, Nie T, Hu Y, Zhou Y, Zhu J, Liu Z, Liu L, Leong KW, Chen Y, Mao HQ. A polyphenol-metal nanoparticle platform for tunable release of liraglutide to improve blood glycemic control and reduce cardiovascular complications in a mouse model of type II diabetes. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31838207 DOI: 10.1016/J.Jconrel.2019.12.014  0.321
2019 Ke X, Howard GP, Tang H, Cheng B, Saung MT, Santos JL, Mao HQ. Physical and chemical profiles of nanoparticles for lymphatic targeting. Advanced Drug Delivery Reviews. PMID 31626825 DOI: 10.1016/J.Addr.2019.09.005  0.305
2019 Hu Y, He Z, Hao Y, Gong L, Pang M, Howard GP, Ahn HH, Brummet M, Chen K, Liu HW, Ke X, Zhu J, Anderson CF, Cui H, Ullman CG, ... ... Mao HQ, et al. Kinetic Control in Assembly of Plasmid DNA/Polycation Complex Nanoparticles. Acs Nano. PMID 31503450 DOI: 10.1021/Acsnano.9B03334  0.334
2019 Nie T, He Z, Zhou Y, Zhu J, Chen K, Liu L, Leong KW, Mao HQ, Chen Y. A Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1. Acs Applied Materials & Interfaces. PMID 31348859 DOI: 10.1021/Acsami.9B10294  0.365
2019 Chen S, Du Z, Zou J, Qiu S, Rao Z, Liu S, Sun X, Xu Y, Zhu Q, Liu X, Mao HQ, Bai Y, Quan D. Promoting Neurite Growth and Schwann Cells Migration by Harnessing Decellularized Nerve Matrix onto Nanofibrous Guidance. Acs Applied Materials & Interfaces. PMID 31002219 DOI: 10.1021/Acsami.9B01066  0.336
2019 Negron K, Khalasawi N, Lu B, Ho CY, Lee J, Shenoy S, Mao HQ, Wang TH, Hanes J, Suk JS. Widespread gene transfer to malignant gliomas with In vitro-to-In vivo correlation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30978431 DOI: 10.1016/J.Jconrel.2019.04.010  0.333
2019 He Z, Hu Y, Gui Z, Zhou Y, Nie T, Zhu J, Liu Z, Chen K, Liu L, Leong KW, Cao P, Chen Y, Mao HQ. Sustained release of exendin-4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30894322 DOI: 10.1016/J.Jconrel.2019.03.014  0.309
2018 He Z, Hu Y, Nie T, Tang H, Zhu J, Chen K, Liu L, Leong KW, Chen Y, Mao HQ. Size-Controlled Lipid Nanoparticle Production Using Turbulent Mixing to Enhance Oral DNA Delivery. Acta Biomaterialia. PMID 30267888 DOI: 10.1016/J.Actbio.2018.09.047  0.35
2018 Tian H, He Z, Sun C, Yang C, Zhao P, Liu L, Leong KW, Mao HQ, Liu Z, Chen Y. Uniform Core-Shell Nanoparticles with Thiolated Hyaluronic Acid Coating to Enhance Oral Delivery of Insulin. Advanced Healthcare Materials. e1800285. PMID 29984479 DOI: 10.1002/Adhm.201800285  0.324
2018 Lin T, Liu S, Chen S, Qiu S, Rao Z, Liu J, Zhu S, Yan L, Mao H, Zhu Q, Quan D, Liu X. Hydrogel derived from porcine decellularized nerve tissue as a promising biomaterial for repairing peripheral nerve defects. Acta Biomaterialia. PMID 29649641 DOI: 10.1016/J.Actbio.2018.04.001  0.318
2018 He Z, Liu Z, Tian H, Hu Y, Liu L, Leong KW, Mao HQ, Chen Y. Scalable production of core-shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin. Nanoscale. PMID 29384554 DOI: 10.1039/C7Nr08047F  0.322
2017 Du J, Liu J, Yao S, Mao H, Peng J, Sun X, Cao Z, Yang Y, Xiao B, Wang Y, Tang P, Wang X. Prompt peripheral nerve regeneration induced by a hierarchically aligned fibrin nanofiber hydrogel. Acta Biomaterialia. PMID 28412554 DOI: 10.1016/J.Actbio.2017.04.010  0.315
2017 He Z, Santos JL, Tian H, Huang H, Hu Y, Liu L, Leong KW, Chen Y, Mao HQ. Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin. Biomaterials. 130: 28-41. PMID 28359018 DOI: 10.1016/J.Biomaterials.2017.03.028  0.303
2016 Santos JL, Ren Y, Vandermark J, Archang MM, Williford JM, Liu HW, Lee J, Wang TH, Mao HQ. Continuous Production of Discrete Plasmid DNA-Polycation Nanoparticles Using Flash Nanocomplexation. Small (Weinheim An Der Bergstrasse, Germany). PMID 27717227 DOI: 10.1002/Smll.201601425  0.333
2016 Yao S, Liu X, Yu S, Wang X, Zhang S, Wu Q, Sun X, Mao H. Co-effects of matrix low elasticity and aligned topography on stem cell neurogenic differentiation and rapid neurite outgrowth. Nanoscale. PMID 27124547 DOI: 10.1039/C6Nr01169A  0.338
2015 Williford JM, Santos JL, Shyam R, Mao HQ. Shape Control in Engineering of Polymeric Nanoparticles for Therapeutic Delivery. Biomaterials Science. 3: 894-907. PMID 26146550 DOI: 10.1039/C5Bm00006H  0.315
2014 Williford JM, Ren Y, Huang K, Pan D, Mao HQ. Shape Transformation Following Reduction-Sensitive PEG Cleavage of Polymer/DNA Nanoparticles. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 8106-8109. PMID 25530853 DOI: 10.1039/C4Tb00967C  0.335
2014 Beh CW, Pan D, Lee J, Jiang X, Liu KJ, Mao HQ, Wang TH. Direct interrogation of DNA content distribution in nanoparticles by a novel microfluidics-based single-particle analysis. Nano Letters. 14: 4729-35. PMID 25054542 DOI: 10.1021/Nl5018404  0.329
2014 Williford JM, Wu J, Ren Y, Archang MM, Leong KW, Mao HQ. Recent advances in nanoparticle-mediated siRNA delivery. Annual Review of Biomedical Engineering. 16: 347-70. PMID 24905873 DOI: 10.1146/Annurev-Bioeng-071813-105119  0.328
2013 Narmada BC, Kang Y, Venkatraman L, Peng Q, Sakban RB, Nugraha B, Jiang X, Bunte RM, So PT, Tucker-Kellogg L, Mao HQ, Yu H. Hepatic stellate cell-targeted delivery of hepatocyte growth factor transgene via bile duct infusion enhances its expression at fibrotic foci to regress dimethylnitrosamine-induced liver fibrosis. Human Gene Therapy. 24: 508-19. PMID 23527815 DOI: 10.1089/Hum.2012.158  0.527
2013 Jiang X, Qu W, Pan D, Ren Y, Williford J, Cui H, Luijten E, Mao H. Gene Delivery: Plasmid-Templated Shape Control of Condensed DNA-Block Copolymer Nanoparticles (Adv. Mater. 2/2013) Advanced Materials. 25: 154-154. DOI: 10.1002/Adma.201370009  0.33
2012 Loo Y, Grigsby CL, Yamanaka YJ, Chellappan MK, Jiang X, Mao HQ, Leong KW. Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 48-56. PMID 22326811 DOI: 10.1016/J.Jconrel.2012.01.041  0.355
2011 Dai H, Jiang X, Leong KW, Mao HQ. Transient depletion of kupffer cells leads to enhanced transgene expression in rat liver following retrograde intrabiliary infusion of plasmid DNA and DNA nanoparticles. Human Gene Therapy. 22: 873-8. PMID 21091274 DOI: 10.1089/Hum.2010.146  0.333
2010 Ren Y, Jiang X, Pan D, Mao HQ. Charge density and molecular weight of polyphosphoramidate gene carrier are key parameters influencing its DNA compaction ability and transfection efficiency. Biomacromolecules. 11: 3432-9. PMID 21067136 DOI: 10.1021/Bm1009574  0.354
2010 Jiang X, Zheng Y, Chen HH, Leong KW, Wang TH, Mao HQ. Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency. Advanced Materials (Deerfield Beach, Fla.). 22: 2556-60. PMID 20440698 DOI: 10.1002/Adma.200903933  0.356
2008 Sun TM, Du JZ, Yan LF, Mao HQ, Wang J. Self-assembled biodegradable micellar nanoparticles of amphiphilic and cationic block copolymer for siRNA delivery. Biomaterials. 29: 4348-55. PMID 18715636 DOI: 10.1016/J.Biomaterials.2008.07.036  0.353
2007 Chua KN, Tang YN, Quek CH, Ramakrishna S, Leong KW, Mao HQ. A dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytes. Acta Biomaterialia. 3: 643-50. PMID 17532276 DOI: 10.1016/J.Actbio.2007.03.012  0.321
2007 Fischer SE, Liu X, Mao HQ, Harden JL. Controlling cell adhesion to surfaces via associating bioactive triblock proteins. Biomaterials. 28: 3325-37. PMID 17459470 DOI: 10.1016/J.Biomaterials.2007.03.026  0.312
2007 Trehan K, Yu C, Bakhru S, Mao H. Novel Hydrogel Microfibers for Tissue Engineering Ieee Transactions On Biomedical Engineering. 65-66. DOI: 10.1115/Biomed2007-38066  0.341
2006 Chua KN, Chai C, Lee PC, Tang YN, Ramakrishna S, Leong KW, Mao HQ. Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells. Biomaterials. 27: 6043-51. PMID 16854459 DOI: 10.1016/J.Biomaterials.2006.06.017  0.307
2006 Feng Q, Chai C, Jiang XS, Leong KW, Mao HQ. Expansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectin. Journal of Biomedical Materials Research. Part A. 78: 781-91. PMID 16739181 DOI: 10.1002/Jbm.A.30829  0.311
2006 Jiang X, Dai H, Leong KW, Goh SH, Mao HQ, Yang YY. Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions. The Journal of Gene Medicine. 8: 477-87. PMID 16389625 DOI: 10.1002/Jgm.868  0.333
2006 Jiang XS, Chai C, Zhang Y, Zhuo RX, Mao HQ, Leong KW. Surface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34+ cells. Biomaterials. 27: 2723-32. PMID 16376984 DOI: 10.1016/J.Biomaterials.2005.12.001  0.478
2006 Jiang X, Dai H, Leong KW, Mao H. 171. PEG-b-PPA/DNA Micelles for Liver Targeted-Gene Delivery Molecular Therapy. 13: S66. DOI: 10.1016/J.Ymthe.2006.08.195  0.329
2005 Lu HF, Chua KN, Zhang PC, Lim WS, Ramakrishna S, Leong KW, Mao HQ. Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance. Acta Biomaterialia. 1: 399-410. PMID 16701821 DOI: 10.1016/J.Actbio.2005.04.003  0.303
2005 Lu HF, Lim WS, Zhang PC, Chia SM, Yu H, Mao HQ, Leong KW. Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture. Tissue Engineering. 11: 1667-77. PMID 16411812 DOI: 10.1089/Ten.2005.11.1667  0.527
2005 Mao HQ, Leong KW. Design of Polyphosphoester-DNA Nanoparticles for Non-Viral Gene Delivery. Advances in Genetics. 53: 275-306. PMID 16243068 DOI: 10.1016/S0065-2660(05)53011-6  0.33
2005 Chia SM, Lin PC, Quek CH, Yin C, Mao HQ, Leong KW, Xu X, Goh CH, Ng ML, Yu H. Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells. Journal of Biotechnology. 118: 434-47. PMID 16026880 DOI: 10.1016/J.Jbiotec.2005.05.012  0.559
2005 Mao HQ, Shipanova-Kadiyala I, Zhao Z, Dang W, Brown A, Leong KW. Biodegradable poly(terephthalate-co-phosphate)s: synthesis, characterization and drug-release properties. Journal of Biomaterials Science. Polymer Edition. 16: 135-61. PMID 15794482 DOI: 10.1163/1568562053115426  0.304
2005 Zhang XQ, Wang XL, Zhang PC, Liu ZL, Zhuo RX, Mao HQ, Leong KW. Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 102: 749-63. PMID 15681095 DOI: 10.1016/J.Jconrel.2004.10.024  0.468
2005 Zhang XQ, Wang XL, Huang SW, Zhuo RX, Liu ZL, Mao HQ, Leong KW. In vitro gene delivery using polyamidoamine dendrimers with a trimesyl core. Biomacromolecules. 6: 341-50. PMID 15638538 DOI: 10.1021/Bm040060N  0.463
2005 Zhang PC, Wang J, Leong KW, Mao HQ. Ternary complexes comprising polyphosphoramidate gene carriers with different types of charge groups improve transfection efficiency. Biomacromolecules. 6: 54-60. PMID 15638504 DOI: 10.1021/Bm040010I  0.317
2005 Ng S, Wu YN, Zhou Y, Toh YE, Ho ZZ, Chia SM, Zhu JH, Mao HQ, Yu H. Optimization of 3-D hepatocyte culture by controlling the physical and chemical properties of the extra-cellular matrices. Biomaterials. 26: 3153-63. PMID 15603810 DOI: 10.1016/J.Biomaterials.2004.08.017  0.534
2005 Chua KN, Lim WS, Zhang P, Lu H, Wen J, Ramakrishna S, Leong KW, Mao HQ. Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold. Biomaterials. 26: 2537-47. PMID 15585256 DOI: 10.1016/J.Biomaterials.2004.07.040  0.345
2005 Tan WJ, Teo GP, Liao K, Leong KW, Mao HQ, Chan V. Adhesion contact dynamics of primary hepatocytes on poly(ethylene terephthalate) surface. Biomaterials. 26: 891-8. PMID 15353200 DOI: 10.1016/J.Biomaterials.2004.03.041  0.313
2005 Bowman K, Sarkar R, Raut S, Shah N, Wang X, Mao H, Leong KW. 779. Oral Delivery of Non-Viral DNA Nanoparticles for Hemophilia A Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.319  0.329
2005 Dai H, Jiang X, Chen Y, Mao H, Leong KW. 196. Role of Kupffer Cells in Hepatic Transgene Expression Mediated by Intrabiliary Infusion of Nonviral Vectors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.199  0.332
2004 Wen J, Mao HQ, Li W, Lin KY, Leong KW. Biodegradable polyphosphoester micelles for gene delivery. Journal of Pharmaceutical Sciences. 93: 2142-57. PMID 15236461 DOI: 10.1002/Jps.20121  0.349
2004 Wang J, Lee IL, Lim WS, Chia SM, Yu H, Leong KW, Mao HQ. Evaluation of collagen and methylated collagen as gene carriers. International Journal of Pharmaceutics. 279: 115-26. PMID 15234800 DOI: 10.1016/J.Ijpharm.2004.04.014  0.54
2004 Wan AC, Mao HQ, Wang S, Phua SH, Lee GP, Pan J, Lu S, Wang J, Leong KW. Poly(phosphoester) ionomers as tissue-engineering scaffolds. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 70: 91-102. PMID 15199588 DOI: 10.1002/Jbm.B.30022  0.3
2004 Quek CH, Li J, Sun T, Chan ML, Mao HQ, Gan LM, Leong KW, Yu H. Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation. Biomaterials. 25: 3531-40. PMID 15020127 DOI: 10.1016/J.Biomaterials.2003.09.112  0.554
2004 Huang SW, Wang J, Zhang PC, Mao HQ, Zhuo RX, Leong KW. Water-soluble and nonionic polyphosphoester: synthesis, degradation, biocompatibility and enhancement of gene expression in mouse muscle. Biomacromolecules. 5: 306-11. PMID 15002988 DOI: 10.1021/Bm034241L  0.501
2004 Li Y, Wang J, Lee CG, Wang CY, Gao SJ, Tang GP, Ma YX, Yu H, Mao HQ, Leong KW, Wang S. CNS gene transfer mediated by a novel controlled release system based on DNA complexes of degradable polycation PPE-EA: a comparison with polyethylenimine/DNA complexes. Gene Therapy. 11: 109-14. PMID 14681704 DOI: 10.1038/Sj.Gt.3302135  0.493
2004 Bowman K, Sarkar R, Wang X, Mao H, Leong KW. 828. Evaluation of Non-Viral Vectors for Gene Therapy of Hemophilia A Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.728  0.336
2004 Dai H, Jiang X, Lim W, Jiang X, Chen Y, Mao H, Leong KW. 357. Selective Depletion of Kupffer Cells Leads to Enhanced Transgene Expression in Rat Liver Following Intraductal Infusion of Naked DNA and DNA Nanoparticles Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.284  0.342
2003 Yin C, Ying L, Zhang PC, Zhuo RX, Kang ET, Leong KW, Mao HQ. High density of immobilized galactose ligand enhances hepatocyte attachment and function. Journal of Biomedical Materials Research. Part A. 67: 1093-104. PMID 14624494 DOI: 10.1002/Jbm.A.10033  0.492
2003 Lu HF, Lim WS, Wang J, Tang ZQ, Zhang PC, Leong KW, Chia SM, Yu H, Mao HQ. Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance. Biomaterials. 24: 4893-903. PMID 14559002 DOI: 10.1016/S0142-9612(03)00404-6  0.528
2003 Wang J, Huang SW, Zhang PC, Mao HQ, Leong KW. Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters. International Journal of Pharmaceutics. 265: 75-84. PMID 14522120 DOI: 10.1016/J.Ijpharm.2003.07.006  0.32
2003 Xu X, Yee WC, Hwang PY, Yu H, Wan AC, Gao S, Boon KL, Mao HQ, Leong KW, Wang S. Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits. Biomaterials. 24: 2405-12. PMID 12699678 DOI: 10.1016/S0142-9612(03)00109-1  0.528
2003 Yin C, Mien Chia S, Hoon Quek C, Yu H, Zhuo RX, Leong KW, Mao HQ. Microcapsules with improved mechanical stability for hepatocyte culture. Biomaterials. 24: 1771-80. PMID 12593959 DOI: 10.1016/S0142-9612(02)00580-X  0.623
2003 Yin C, Liao K, Mao HQ, Leong KW, Zhuo RX, Chan V. Adhesion contact dynamics of HepG2 cells on galactose-immobilized substrates. Biomaterials. 24: 837-50. PMID 12485802 DOI: 10.1016/S0142-9612(02)00416-7  0.496
2002 Wang J, Zhang PC, Lu HF, Ma N, Wang S, Mao HQ, Leong KW. New polyphosphoramidate with a spermidine side chain as a gene carrier. Journal of Controlled Release : Official Journal of the Controlled Release Society. 83: 157-68. PMID 12220847 DOI: 10.1016/S0168-3659(02)00180-3  0.336
2002 Chia SM, Wan AC, Quek CH, Mao HQ, Xu X, Shen L, Ng ML, Leong KW, Yu H. Multi-layered microcapsules for cell encapsulation. Biomaterials. 23: 849-56. PMID 11774851 DOI: 10.1016/S0142-9612(01)00191-0  0.513
2001 Wang S, Wan AC, Xu X, Gao S, Mao HQ, Leong KW, Yu H. A new nerve guide conduit material composed of a biodegradable poly(phosphoester). Biomaterials. 22: 1157-69. PMID 11352095 DOI: 10.1016/S0142-9612(00)00356-2  0.551
2001 Wan AC, Mao HQ, Wang S, Leong KW, Ong LK, Yu H. Fabrication of poly(phosphoester) nerve guides by immersion precipitation and the control of porosity. Biomaterials. 22: 1147-56. PMID 11352094 DOI: 10.1016/S0142-9612(00)00355-0  0.526
1999 Truong-Le VL, Walsh SM, Schweibert E, Mao HQ, Guggino WB, August JT, Leong KW. Gene transfer by DNA-gelatin nanospheres. Archives of Biochemistry and Biophysics. 361: 47-56. PMID 9882427 DOI: 10.1006/Abbi.1998.0975  0.334
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