| Year |
Citation |
Score |
| 2021 |
Hu CH, Neissel Valente MW, Scott Halpern O, Jusuf S, Khan JA, Locke GA, Duke GJ, Liu X, Duclos FJ, Wexler RR, Kick EK, Smallheer JM. Small Molecule and Macrocyclic Pyrazole Derived Inhibitors of Myeloperoxidase (MPO). Bioorganic & Medicinal Chemistry Letters. 128010. PMID 33811992 DOI: 10.1016/j.bmcl.2021.128010 |
0.37 |
|
| 2020 |
Shaw SA, Vokits BP, Dilger AK, Viet A, Clark CG, Abell LM, Locke GA, Duke G, Kopcho LM, Dongre A, Gao J, Krishnakumar A, Jusuf S, Khan J, Spronk SA, ... ... Kick EK, et al. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorganic & Medicinal Chemistry. 28: 115723. PMID 33007547 DOI: 10.1016/j.bmc.2020.115723 |
0.358 |
|
| 2018 |
Wurtz NR, Viet A, Shaw SA, Dilger A, Valente MN, Khan JA, Jusuf S, Narayanan R, Fernando G, Lo F, Liu X, Locke GA, Kopcho L, Abell LM, Sleph P, ... ... Kick EK, et al. Potent Triazolopyridine Myeloperoxidase Inhibitors. Acs Medicinal Chemistry Letters. 9: 1175-1180. PMID 30613322 DOI: 10.1021/acsmedchemlett.8b00308 |
0.345 |
|
| 2017 |
Duclos F, Abell LM, Harden DG, Pike K, Nowak K, Locke GA, Duke GJ, Liu X, Fernando G, Shaw SA, Vokits BP, Wurtz NR, Viet A, Valente MN, Stachura S, ... ... Kick EK, et al. Triazolopyrimidines identified as reversible myeloperoxidase inhibitors. Medchemcomm. 8: 2093-2099. PMID 30108726 DOI: 10.1039/c7md00268h |
0.321 |
|
| 1997 |
Kick EK, Roe DC, Skillman AG, Liu G, Ewing TJ, Sun Y, Kuntz ID, Ellman JA. Structure-based design and combinatorial chemistry yield low nanomolar inhibitors of cathepsin D. Chemistry & Biology. 4: 297-307. PMID 9195867 DOI: 10.1016/S1074-5521(97)90073-9 |
0.325 |
|
| 1995 |
Kick EK, Ellman JA. Expedient method for the solid-phase synthesis of aspartic acid protease inhibitors directed toward the generation of libraries. Journal of Medicinal Chemistry. 38: 1427-30. PMID 7739000 DOI: 10.1021/Jm00009A002 |
0.316 |
|
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