David P. Bartel, Ph.D. - Publications

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
"RNA World", regulation of gene expression by small RNAs found in animal and plant cells
Website:
https://biology.mit.edu/people/david_bartel

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Agarwal V, Subtelny AO, Thiru P, Ulitsky I, Bartel DP. Predicting microRNA targeting efficacy in Drosophila. Genome Biology. 19: 152. PMID 30286781 DOI: 10.1186/s13059-018-1504-3  0.32
2017 Chen GR, Sive H, Bartel DP. A Seed Mismatch Enhances Argonaute2-Catalyzed Cleavage and Partially Rescues Severely Impaired Cleavage Found in Fish. Molecular Cell. 68: 1095-1107.e5. PMID 29272705 DOI: 10.1016/j.molcel.2017.11.032  0.52
2017 Rissland OS, Subtelny AO, Wang M, Lugowski A, Nicholson B, Laver JD, Sidhu SS, Smibert CA, Lipshitz HD, Bartel DP. The influence of microRNAs and poly(A) tail length on endogenous mRNA-protein complexes. Genome Biology. 18: 211. PMID 29089021 DOI: 10.1186/s13059-017-1330-z  0.32
2017 Wu X, Bartel DP. Widespread Influence of 3'-End Structures on Mammalian mRNA Processing and Stability. Cell. 169: 905-917.e11. PMID 28525757 DOI: 10.1016/j.cell.2017.04.036  1
2017 Wu X, Bartel DP. kpLogo: positional k-mer analysis reveals hidden specificity in biological sequences. Nucleic Acids Research. PMID 28460012 DOI: 10.1093/nar/gkx323  1
2017 Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, ... ... Bartel DP, et al. Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Systems. PMID 28131822 DOI: 10.1016/j.cels.2016.12.011  0.32
2016 Eichhorn SW, Subtelny AO, Kronja I, Kwasnieski JC, Orr-Weaver TL, Bartel DP. mRNA Poly(A)-tail Changes Specified by Deadenylation Broadly Reshape Translation in Drosophila Oocytes and Early Embryos. Elife. 5. PMID 27474798 DOI: 10.7554/eLife.16955  0.32
2016 Weinberg DE, Shah P, Eichhorn SW, Hussmann JA, Plotkin JB, Bartel DP. Improved Ribosome-Footprint and mRNA Measurements Provide Insights into Dynamics and Regulation of Yeast Translation. Cell Reports. PMID 26876183 DOI: 10.1016/j.celrep.2016.01.043  1
2015 Fang W, Bartel DP. The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes. Molecular Cell. 60: 131-45. PMID 26412306 DOI: 10.1016/j.molcel.2015.08.015  1
2015 Wong SF, Agarwal V, Mansfield JH, Denans N, Schwartz MG, Prosser HM, Pourquié O, Bartel DP, Tabin CJ, McGlinn E. Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs. Proceedings of the National Academy of Sciences of the United States of America. 112: E4884-93. PMID 26283362 DOI: 10.1073/pnas.1512655112  1
2015 Agarwal V, Bell GW, Nam JW, Bartel DP. Predicting effective microRNA target sites in mammalian mRNAs. Elife. 4. PMID 26267216 DOI: 10.7554/eLife.05005  1
2015 Hezroni H, Koppstein D, Schwartz MG, Avrutin A, Bartel DP, Ulitsky I. Principles of long noncoding RNA evolution derived from direct comparison of transcriptomes in 17 species. Cell Reports. 11: 1110-22. PMID 25959816 DOI: 10.1016/j.celrep.2015.04.023  1
2015 Koppstein D, Ashour J, Bartel DP. Sequencing the cap-snatching repertoire of H1N1 influenza provides insight into the mechanism of viral transcription initiation. Nucleic Acids Research. 43: 5052-64. PMID 25901029 DOI: 10.1093/nar/gkv333  1
2014 Eichhorn SW, Guo H, McGeary SE, Rodriguez-Mias RA, Shin C, Baek D, Hsu SH, Ghoshal K, Villén J, Bartel DP. mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues. Molecular Cell. 56: 104-15. PMID 25263593 DOI: 10.1016/j.molcel.2014.08.028  1
2014 Guo JU, Agarwal V, Guo H, Bartel DP. Expanded identification and characterization of mammalian circular RNAs. Genome Biology. 15: 409. PMID 25070500 DOI: 10.1186/s13059-014-0409-z  1
2014 Kronja I, Yuan B, Eichhorn SW, Dzeyk K, Krijgsveld J, Bartel DP, Orr-Weaver TL. Widespread changes in the posttranscriptional landscape at the Drosophila oocyte-to-embryo transition. Cell Reports. 7: 1495-508. PMID 24882012 DOI: 10.1016/j.celrep.2014.05.002  1
2014 Denzler R, Agarwal V, Stefano J, Bartel DP, Stoffel M. Assessing the ceRNA hypothesis with quantitative measurements of miRNA and target abundance. Molecular Cell. 54: 766-76. PMID 24793693 DOI: 10.1016/j.molcel.2014.03.045  1
2014 Nam JW, Rissland OS, Koppstein D, Abreu-Goodger C, Jan CH, Agarwal V, Yildirim MA, Rodriguez A, Bartel DP. Global analyses of the effect of different cellular contexts on microRNA targeting. Molecular Cell. 53: 1031-43. PMID 24631284 DOI: 10.1016/j.molcel.2014.02.013  1
2014 Subtelny AO, Eichhorn SW, Chen GR, Sive H, Bartel DP. Poly(A)-tail profiling reveals an embryonic switch in translational control. Nature. 508: 66-71. PMID 24476825 DOI: 10.1038/nature13007  1
2013 Spies N, Burge CB, Bartel DP. 3' UTR-isoform choice has limited influence on the stability and translational efficiency of most mRNAs in mouse fibroblasts. Genome Research. 23: 2078-90. PMID 24072873 DOI: 10.1101/gr.156919.113  1
2013 Ulitsky I, Bartel DP. lincRNAs: genomics, evolution, and mechanisms. Cell. 154: 26-46. PMID 23827673 DOI: 10.1016/j.cell.2013.06.020  1
2013 Curtis EA, Bartel DP. Synthetic shuffling and in vitro selection reveal the rugged adaptive fitness landscape of a kinase ribozyme. Rna (New York, N.Y.). 19: 1116-28. PMID 23798664 DOI: 10.1261/rna.037572.112  1
2013 Dumesic PA, Natarajan P, Chen C, Drinnenberg IA, Schiller BJ, Thompson J, Moresco JJ, Yates JR, Bartel DP, Madhani HD. Stalled spliceosomes are a signal for RNAi-mediated genome defense. Cell. 152: 957-68. PMID 23415457 DOI: 10.1016/j.cell.2013.01.046  1
2013 Auyeung VC, Ulitsky I, McGeary SE, Bartel DP. Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing. Cell. 152: 844-58. PMID 23415231 DOI: 10.1016/j.cell.2013.01.031  1
2012 Ulitsky I, Shkumatava A, Jan CH, Subtelny AO, Koppstein D, Bell GW, Sive H, Bartel DP. Extensive alternative polyadenylation during zebrafish development. Genome Research. 22: 2054-66. PMID 22722342 DOI: 10.1101/gr.139733.112  1
2012 Nakanishi K, Weinberg DE, Bartel DP, Patel DJ. Structure of yeast Argonaute with guide RNA. Nature. 486: 368-74. PMID 22722195 DOI: 10.1038/nature11211  1
2012 Nam JW, Bartel DP. Long noncoding RNAs in C. elegans. Genome Research. 22: 2529-40. PMID 22707570 DOI: 10.1101/gr.140475.112  1
2012 Nodine MD, Bartel DP. Maternal and paternal genomes contribute equally to the transcriptome of early plant embryos. Nature. 482: 94-7. PMID 22266940 DOI: 10.1038/nature10756  1
2012 Bernstein DA, Vyas VK, Weinberg DE, Drinnenberg IA, Bartel DP, Fink GR. Candida albicans Dicer (CaDcr1) is required for efficient ribosomal and spliceosomal RNA maturation. Proceedings of the National Academy of Sciences of the United States of America. 109: 523-8. PMID 22173636 DOI: 10.1073/pnas.1118859109  1
2011 Ulitsky I, Shkumatava A, Jan CH, Sive H, Bartel DP. Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell. 147: 1537-50. PMID 22196729 DOI: 10.1016/j.cell.2011.11.055  1
2011 Rissland OS, Hong SJ, Bartel DP. MicroRNA destabilization enables dynamic regulation of the miR-16 family in response to cell-cycle changes. Molecular Cell. 43: 993-1004. PMID 21925387 DOI: 10.1016/j.molcel.2011.08.021  1
2011 Drinnenberg IA, Fink GR, Bartel DP. Compatibility with killer explains the rise of RNAi-deficient fungi. Science (New York, N.Y.). 333: 1592. PMID 21921191 DOI: 10.1126/science.1209575  1
2011 Garcia DM, Baek D, Shin C, Bell GW, Grimson A, Bartel DP. Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs. Nature Structural & Molecular Biology. 18: 1139-46. PMID 21909094 DOI: 10.1038/nsmb.2115  1
2011 Shechner DM, Bartel DP. The structural basis of RNA-catalyzed RNA polymerization. Nature Structural & Molecular Biology. 18: 1036-42. PMID 21857665 DOI: 10.1038/nsmb.2107  1
2011 Weinberg DE, Nakanishi K, Patel DJ, Bartel DP. The inside-out mechanism of Dicers from budding yeasts. Cell. 146: 262-76. PMID 21784247 DOI: 10.1016/j.cell.2011.06.021  1
2011 Schnall-Levin M, Rissland OS, Johnston WK, Perrimon N, Bartel DP, Berger B. Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs. Genome Research. 21: 1395-403. PMID 21685129 DOI: 10.1101/gr.121210.111  1
2011 Koldobskaya Y, Duguid EM, Shechner DM, Suslov NB, Ye J, Sidhu SS, Bartel DP, Koide S, Kossiakoff AA, Piccirilli JA. A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination. Nature Structural & Molecular Biology. 18: 100-6. PMID 21151117 DOI: 10.1038/nsmb.1945  1
2011 Jan CH, Friedman RC, Ruby JG, Bartel DP. Formation, regulation and evolution of Caenorhabditis elegans 3'UTRs. Nature. 469: 97-101. PMID 21085120 DOI: 10.1038/nature09616  1
2010 Nodine MD, Bartel DP. MicroRNAs prevent precocious gene expression and enable pattern formation during plant embryogenesis. Genes & Development. 24: 2678-92. PMID 21123653 DOI: 10.1101/gad.1986710  1
2010 Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 466: 835-40. PMID 20703300 DOI: 10.1038/nature09267  1
2010 Shin C, Nam JW, Farh KK, Chiang HR, Shkumatava A, Bartel DP. Expanding the microRNA targeting code: functional sites with centered pairing. Molecular Cell. 38: 789-802. PMID 20620952 DOI: 10.1016/j.molcel.2010.06.005  1
2010 Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP. Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes & Development. 24: 992-1009. PMID 20413612 DOI: 10.1101/gad.1884710  1
2009 Shechner DM, Grant RA, Bagby SC, Koldobskaya Y, Piccirilli JA, Bartel DP. Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science (New York, N.Y.). 326: 1271-5. PMID 19965478 DOI: 10.1126/science.1174676  1
2009 Bagby SC, Bergman NH, Shechner DM, Yen C, Bartel DP. A class I ligase ribozyme with reduced Mg2+ dependence: Selection, sequence analysis, and identification of functional tertiary interactions. Rna (New York, N.Y.). 15: 2129-46. PMID 19946040 DOI: 10.1261/rna.1912509  1
2009 McGlinn E, Yekta S, Mansfield JH, Soutschek J, Bartel DP, Tabin CJ. In ovo application of antagomiRs indicates a role for miR-196 in patterning the chick axial skeleton through Hox gene regulation. Proceedings of the National Academy of Sciences of the United States of America. 106: 18610-5. PMID 19846767 DOI: 10.1073/pnas.0910374106  1
2009 Drinnenberg IA, Weinberg DE, Xie KT, Mower JP, Wolfe KH, Fink GR, Bartel DP. RNAi in budding yeast. Science (New York, N.Y.). 326: 544-50. PMID 19745116 DOI: 10.1126/science.1176945  1
2009 Mayr C, Bartel DP. Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell. 138: 673-84. PMID 19703394 DOI: 10.1016/j.cell.2009.06.016  1
2009 Kim J, Bartel DP. Allelic imbalance sequencing reveals that single-nucleotide polymorphisms frequently alter microRNA-directed repression. Nature Biotechnology. 27: 472-7. PMID 19396161 DOI: 10.1038/nbt.1540  1
2009 Shkumatava A, Stark A, Sive H, Bartel DP. Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Genes & Development. 23: 466-81. PMID 19240133 DOI: 10.1101/gad.1745709  1
2009 Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 136: 215-33. PMID 19167326 DOI: 10.1016/j.cell.2009.01.002  1
2009 Friedman RC, Farh KK, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Research. 19: 92-105. PMID 18955434 DOI: 10.1101/gr.082701.108  1
2008 Meyers BC, Axtell MJ, Bartel B, Bartel DP, Baulcombe D, Bowman JL, Cao X, Carrington JC, Chen X, Green PJ, Griffiths-Jones S, Jacobsen SE, Mallory AC, Martienssen RA, Poethig RS, et al. Criteria for annotation of plant MicroRNAs. The Plant Cell. 20: 3186-90. PMID 19074682 DOI: 10.1105/tpc.108.064311  0.4
2008 Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R. Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes & Development. 22: 2773-85. PMID 18923076 DOI: 10.1101/gad.1705308  1
2008 Grimson A, Srivastava M, Fahey B, Woodcroft BJ, Chiang HR, King N, Degnan BM, Rokhsar DS, Bartel DP. Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals. Nature. 455: 1193-7. PMID 18830242 DOI: 10.1038/nature07415  1
2008 Yekta S, Tabin CJ, Bartel DP. MicroRNAs in the Hox network: an apparent link to posterior prevalence. Nature Reviews. Genetics. 9: 789-96. PMID 18781158 DOI: 10.1038/nrg2400  1
2008 Bühler M, Spies N, Bartel DP, Moazed D. TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway. Nature Structural & Molecular Biology. 15: 1015-23. PMID 18776903 DOI: 10.1038/nsmb.1481  1
2008 Marson A, Levine SS, Cole MF, Frampton GM, Brambrink T, Johnstone S, Guenther MG, Johnston WK, Wernig M, Newman J, Calabrese JM, Dennis LM, Volkert TL, Gupta S, Love J, ... ... Bartel DP, et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell. 134: 521-33. PMID 18692474 DOI: 10.1016/j.cell.2008.07.020  1
2008 Baek D, Villén J, Shin C, Camargo FD, Gygi SP, Bartel DP. The impact of microRNAs on protein output. Nature. 455: 64-71. PMID 18668037 DOI: 10.1038/nature07242  1
2008 Batista PJ, Ruby JG, Claycomb JM, Chiang R, Fahlgren N, Kasschau KD, Chaves DA, Gu W, Vasale JJ, Duan S, Conte D, Luo S, Schroth GP, Carrington JC, Bartel DP, et al. PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans. Molecular Cell. 31: 67-78. PMID 18571452 DOI: 10.1016/j.molcel.2008.06.002  1
2008 Addo-Quaye C, Eshoo TW, Bartel DP, Axtell MJ. Endogenous siRNA and miRNA targets identified by sequencing of the Arabidopsis degradome. Current Biology : Cb. 18: 758-62. PMID 18472421 DOI: 10.1016/j.cub.2008.04.042  1
2008 Okamura K, Chung WJ, Ruby JG, Guo H, Bartel DP, Lai EC. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature. 453: 803-6. PMID 18463630 DOI: 10.1038/nature07015  1
2008 Müller UF, Bartel DP. Improved polymerase ribozyme efficiency on hydrophobic assemblies. Rna (New York, N.Y.). 14: 552-62. PMID 18230767 DOI: 10.1261/rna.494508  1
2008 Stark A, Bushati N, Jan CH, Kheradpour P, Hodges E, Brennecke J, Bartel DP, Cohen SM, Kellis M. A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands. Genes & Development. 22: 8-13. PMID 18172160 DOI: 10.1101/gad.1613108  1
2008 Zhou B, Wang S, Mayr C, Bartel DP, Lodish HF. miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 17, (7080-7085) DOI: 10.1073/pnas.0702409104) Proceedings of the National Academy of Sciences of the United States of America. 105: 18071. DOI: 10.1073/pnas.0809324105  1
2007 Miska EA, Alvarez-Saavedra E, Abbott AL, Lau NC, Hellman AB, McGonagle SM, Bartel DP, Ambros VR, Horvitz HR. Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. Plos Genetics. 3: e215. PMID 18085825 DOI: 10.1371/journal.pgen.0030215  0.64
2007 Stark A, Lin MF, Kheradpour P, Pedersen JS, Parts L, Carlson JW, Crosby MA, Rasmussen MD, Roy S, Deoras AN, Ruby JG, Brennecke J, Hodges E, ... ... Bartel DP, et al. Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature. 450: 219-32. PMID 17994088 DOI: 10.1038/nature06340  1
2007 Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC. Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Research. 17: 1850-64. PMID 17989254 DOI: 10.1101/gr.6597907  1
2007 Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Molecular Cell. 27: 91-105. PMID 17612493 DOI: 10.1016/j.molcel.2007.06.017  1
2007 Axtell MJ, Snyder JA, Bartel DP. Common functions for diverse small RNAs of land plants. The Plant Cell. 19: 1750-69. PMID 17601824 DOI: 10.1105/tpc.107.051706  1
2007 Ruby JG, Jan CH, Bartel DP. Intronic microRNA precursors that bypass Drosha processing. Nature. 448: 83-6. PMID 17589500 DOI: 10.1038/nature05983  1
2007 Zhou B, Wang S, Mayr C, Bartel DP, Lodish HF. miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proceedings of the National Academy of Sciences of the United States of America. 104: 7080-5. PMID 17438277 DOI: 10.1073/pnas.0702409104  1
2007 Mayr C, Hemann MT, Bartel DP. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science (New York, N.Y.). 315: 1576-9. PMID 17322030 DOI: 10.1126/science.1137999  1
2006 Rajagopalan R, Vaucheret H, Trejo J, Bartel DP. A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana. Genes & Development. 20: 3407-25. PMID 17182867 DOI: 10.1101/gad.1476406  1
2006 Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP. Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell. 127: 1193-207. PMID 17174894 DOI: 10.1016/j.cell.2006.10.040  1
2006 Axtell MJ, Jan C, Rajagopalan R, Bartel DP. A two-hit trigger for siRNA biogenesis in plants. Cell. 127: 565-77. PMID 17081978 DOI: 10.1016/j.cell.2006.09.032  1
2006 Lau NC, Seto AG, Kim J, Kuramochi-Miyagawa S, Nakano T, Bartel DP, Kingston RE. Characterization of the piRNA complex from rat testes. Science (New York, N.Y.). 313: 363-7. PMID 16778019 DOI: 10.1126/science.1130164  1
2006 Jones-Rhoades MW, Bartel DP, Bartel B. MicroRNAS and their regulatory roles in plants. Annual Review of Plant Biology. 57: 19-53. PMID 16669754 DOI: 10.1146/annurev.arplant.57.032905.105218  1
2006 Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, ... ... Bartel DP, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 125: 301-13. PMID 16630818 DOI: 10.1016/j.cell.2006.02.043  1
2006 Vaucheret H, Mallory AC, Bartel DP. AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1. Molecular Cell. 22: 129-36. PMID 16600876 DOI: 10.1016/j.molcel.2006.03.011  1
2005 Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT, Baskerville S, Bartel DP, Tabin CJ. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature. 438: 671-4. PMID 16319892 DOI: 10.1038/nature04138  1
2005 Farh KK, Grimson A, Jan C, Lewis BP, Johnston WK, Lim LP, Burge CB, Bartel DP. The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science (New York, N.Y.). 310: 1817-21. PMID 16308420 DOI: 10.1126/science.1121158  1
2005 Schultes EA, Spasic A, Mohanty U, Bartel DP. Compact and ordered collapse of randomly generated RNA sequences. Nature Structural & Molecular Biology. 12: 1130-6. PMID 16273104 DOI: 10.1038/nsmb1014  1
2005 Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell. 123: 607-20. PMID 16271386 DOI: 10.1016/j.cell.2005.08.044  1
2005 Curtis EA, Bartel DP. New catalytic structures from an existing ribozyme. Nature Structural & Molecular Biology. 12: 994-1000. PMID 16228005 DOI: 10.1038/nsmb1003  1
2005 Li M, Jones-Rhoades MW, Lau NC, Bartel DP, Rougvie AE. Regulatory mutations of mir-48, a C. elegans let-7 family MicroRNA, cause developmental timing defects. Developmental Cell. 9: 415-22. PMID 16139229 DOI: 10.1016/j.devcel.2005.08.002  1
2005 Abbott AL, Alvarez-Saavedra E, Miska EA, Lau NC, Bartel DP, Horvitz HR, Ambros V. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Developmental Cell. 9: 403-14. PMID 16139228 DOI: 10.1016/j.devcel.2005.07.009  0.64
2005 Gasciolli V, Mallory AC, Bartel DP, Vaucheret H. Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs. Current Biology : Cb. 15: 1494-500. PMID 16040244 DOI: 10.1016/j.cub.2005.07.024  1
2005 Lawrence MS, Bartel DP. New ligase-derived RNA polymerase ribozymes. Rna (New York, N.Y.). 11: 1173-80. PMID 15987804 DOI: 10.1261/rna.2110905  1
2005 Axtell MJ, Bartel DP. Antiquity of microRNAs and their targets in land plants. The Plant Cell. 17: 1658-73. PMID 15849273 DOI: 10.1105/tpc.105.032185  1
2005 Mallory AC, Bartel DP, Bartel B. MicroRNA-directed regulation of Arabidopsis AUXIN RESPONSE FACTOR17 is essential for proper development and modulates expression of early auxin response genes. The Plant Cell. 17: 1360-75. PMID 15829600 DOI: 10.1105/tpc.105.031716  1
2005 Giraldez AJ, Cinalli RM, Glasner ME, Enright AJ, Thomson JM, Baskerville S, Hammond SM, Bartel DP, Schier AF. MicroRNAs regulate brain morphogenesis in zebrafish. Science (New York, N.Y.). 308: 833-8. PMID 15774722 DOI: 10.1126/science.1109020  1
2005 Baskerville S, Bartel DP. Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. Rna (New York, N.Y.). 11: 241-7. PMID 15701730 DOI: 10.1261/rna.7240905  1
2005 Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 433: 769-73. PMID 15685193 DOI: 10.1038/nature03315  1
2005 Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 120: 15-20. PMID 15652477 DOI: 10.1016/j.cell.2004.12.035  1
2004 Vazquez F, Vaucheret H, Rajagopalan R, Lepers C, Gasciolli V, Mallory AC, Hilbert JL, Bartel DP, Crété P. Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs. Molecular Cell. 16: 69-79. PMID 15469823 DOI: 10.1016/j.molcel.2004.09.028  1
2004 Ohler U, Yekta S, Lim LP, Bartel DP, Burge CB. Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. Rna (New York, N.Y.). 10: 1309-22. PMID 15317971 DOI: 10.1261/rna.5206304  1
2004 Mallory AC, Reinhart BJ, Jones-Rhoades MW, Tang G, Zamore PD, Barton MK, Bartel DP. MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' region. The Embo Journal. 23: 3356-64. PMID 15282547 DOI: 10.1038/sj.emboj.7600340  1
2004 Mallory AC, Dugas DV, Bartel DP, Bartel B. MicroRNA regulation of NAC-domain targets is required for proper formation and separation of adjacent embryonic, vegetative, and floral organs. Current Biology : Cb. 14: 1035-46. PMID 15202996 DOI: 10.1016/j.cub.2004.06.022  1
2004 Jones-Rhoades MW, Bartel DP. Computational identification of plant microRNAs and their targets, including a stress-induced miRNA. Molecular Cell. 14: 787-99. PMID 15200956 DOI: 10.1016/j.molcel.2004.05.027  1
2004 Bartel DP, Chen CZ. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nature Reviews. Genetics. 5: 396-400. PMID 15143321 DOI: 10.1038/nrg1328  1
2004 Vaucheret H, Vazquez F, Crété P, Bartel DP. The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development. Genes & Development. 18: 1187-97. PMID 15131082 DOI: 10.1101/gad.1201404  1
2004 Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science (New York, N.Y.). 304: 594-6. PMID 15105502 DOI: 10.1126/science.1097434  1
2004 Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 116: 281-97. PMID 14744438 DOI: 10.1016/S0092-8674(04)00045-5  1
2004 Bergman NH, Lau NC, Lehnert V, Westhof E, Bartel DP. The three-dimensional architecture of the class I ligase ribozyme. Rna (New York, N.Y.). 10: 176-84. PMID 14730016 DOI: 10.1261/rna.5177504  1
2004 Chen CZ, Li L, Lodish HF, Bartel DP. MicroRNAs modulate hematopoietic lineage differentiation. Science (New York, N.Y.). 303: 83-6. PMID 14657504 DOI: 10.1126/science.1091903  1
2003 Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell. 115: 787-98. PMID 14697198 DOI: 10.1016/S0092-8674(03)01018-3  1
2003 Unrau PJ, Bartel DP. An oxocarbenium-ion intermediate of a ribozyme reaction indicated by kinetic isotope effects. Proceedings of the National Academy of Sciences of the United States of America. 100: 15393-7. PMID 14668444 DOI: 10.1073/pnas.2433147100  1
2003 Müller UF, Bartel DP. Substrate 2'-hydroxyl groups required for ribozyme-catalyzed polymerization. Chemistry & Biology. 10: 799-806. PMID 14522050 DOI: 10.1016/S1074-5521(03)00171-6  1
2003 Chapple KE, Bartel DP, Unrau PJ. Combinatorial minimization and secondary structure determination of a nucleotide synthase ribozyme. Rna (New York, N.Y.). 9: 1208-20. PMID 13130135 DOI: 10.1261/rna.5500603  1
2003 Lau NC, Bartel DP. Censors of the genome. Scientific American. 289: 34-41. PMID 12884536  1
2003 Lawrence MS, Bartel DP. Processivity of ribozyme-catalyzed RNA polymerization. Biochemistry. 42: 8748-55. PMID 12873135 DOI: 10.1021/bi034228l  1
2003 Bartel B, Bartel DP. MicroRNAs: at the root of plant development? Plant Physiology. 132: 709-17. PMID 12805599 DOI: 10.1104/pp.103.023630  1
2003 Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP. The microRNAs of Caenorhabditis elegans. Genes & Development. 17: 991-1008. PMID 12672692 DOI: 10.1101/gad.1074403  1
2003 Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP. Vertebrate microRNA genes. Science (New York, N.Y.). 299: 1540. PMID 12624257 DOI: 10.1126/science.1080372  1
2003 Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T. A uniform system for microRNA annotation. Rna (New York, N.Y.). 9: 277-9. PMID 12592000 DOI: 10.1261/rna.2183803  1
2003 Tang G, Reinhart BJ, Bartel DP, Zamore PD. A biochemical framework for RNA silencing in plants. Genes & Development. 17: 49-63. PMID 12514099 DOI: 10.1101/gad.1048103  1
2002 Rhoades MW, Reinhart BJ, Lim LP, Burge CB, Bartel B, Bartel DP. Prediction of plant microRNA targets. Cell. 110: 513-20. PMID 12202040 DOI: 10.1016/S0092-8674(02)00863-2  1
2002 Reinhart BJ, Bartel DP. Small RNAs correspond to centromere heterochromatic repeats. Science (New York, N.Y.). 297: 1831. PMID 12193644 DOI: 10.1126/science.1077183  1
2002 Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP. MicroRNAs in plants. Genes & Development. 16: 1616-26. PMID 12101121 DOI: 10.1101/gad.1004402  1
2002 Merryman C, Weinstein E, Wnuk SF, Bartel DP. A bifunctional tRNA for in vitro selection Chemistry and Biology. 9: 741-746. PMID 12079786 DOI: 10.1016/S1074-5521(02)00161-8  1
2002 Baskerville S, Bartel DP. A ribozyme that ligates RNA to protein Proceedings of the National Academy of Sciences of the United States of America. 99: 9154-9159. PMID 12077317 DOI: 10.1073/pnas.142153799  1
2002 Glasner ME, Bergman NH, Bartel DP. Metal ion requirements for structure and catalysis of an RNA ligase ribozyme Biochemistry. 41: 8103-8112. PMID 12069603 DOI: 10.1021/bi012179b  1
2002 Bartel DP, Unrau P. Reconstructing the RNA world | Reconstruire le monde ARN Biofutur. 37-41.  1
2001 Lau NC, Lim LP, Weinstein EG, Bartel DP. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans Science. 294: 858-862. PMID 11679671 DOI: 10.1126/science.1065062  1
2001 Johnston WK, Unrau PJ, Lawrence MS, Glasner ME, Bartel DP. RNA-catalyzed RNA polymerization: Accurate and general RNA-templated primer extension Science. 292: 1319-1325. PMID 11358999 DOI: 10.1126/science.1060786  1
2001 Curtis EA, Bartel DP. The hammerhead cleavage reaction in monovalent cations. Rna (New York, N.Y.). 7: 546-52. PMID 11345433 DOI: 10.1017/S1355838201002357  1
2001 Tuschl T, Sharp PA, Bartel DP. A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation. Rna (New York, N.Y.). 7: 29-43. PMID 11214178 DOI: 10.1017/S1355838201001510  1
2001 Szostak JW, Bartel DP, Luisi PL. Synthesizing life. Nature. 409: 387-90. PMID 11201752 DOI: 10.1038/35053176  1
2000 Glasner ME, Yen CC, Ekland EH, Bartel DP. Recognition of nucleoside triphosphates during RNA-catalyzed primer extension. Biochemistry. 39: 15556-62. PMID 11112542 DOI: 10.1021/bi002174z  1
2000 Schultes EA, Bartel DP. One sequence, two ribozymes: Implications for the emergence of new ribozyme folds Science. 289: 448-452. PMID 10903205 DOI: 10.1126/science.289.5478.448  1
2000 Zamore PD, Tuschl T, Sharp PA, Bartel DP. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell. 101: 25-33. PMID 10778853 DOI: 10.1016/S0092-8674(00)80620-0  1
2000 Bergman NH, Johnston WK, Bartel DP. Kinetic framework for ligation by an efficient RNA ligase ribozyme Biochemistry. 39: 3115-3123. PMID 10715133 DOI: 10.1021/bi992654u  1
1999 Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. Targeted mRNA degradation by double-stranded RNA in vitro. Genes & Development. 13: 3191-7. PMID 10617568 DOI: 10.1101/gad.13.24.3191  1
1999 Williams KP, Martindale KA, Bartel DP. Resuming translation on tmRNA: A unique mode of determining a reading frame Embo Journal. 18: 5423-5433. PMID 10508174 DOI: 10.1093/emboj/18.19.5423  1
1999 Bartel DP. Creation and evolution of new ribozymes Biological Bulletin. 196: 322-323. PMID 10447351  1
1999 Zamore PD, Bartel DP, Lehmann R, Williamson JR. The PUMILIO-RNA interaction: a single RNA-binding domain monomer recognizes a bipartite target sequence. Biochemistry. 38: 596-604. PMID 9888799 DOI: 10.1021/bi982264s  1
1999 Unrau PJ, Bartel DP, Koch G, Dandekar T. RNA-catalysed nucleotide synthesis Chemtracts. 12: 938-943. DOI: 10.1038/26193  1
1999 Bartel DP, Unrau PJ. Constructing an RNA world Trends in Genetics. 15: M9-M13. DOI: 10.1016/S0168-9525(99)01898-3  1
1998 Tuschl T, Sharp PA, Bartel DP. Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library. The Embo Journal. 17: 2637-50. PMID 9564046 DOI: 10.1093/emboj/17.9.2637  1
1998 Williams KP, Bartel DP. The tmRNA website Nucleic Acids Research. 26: 163-165. PMID 9399824 DOI: 10.1093/nar/26.1.163  1
1997 Sabeti PC, Unrau PJ, Bartel DP. Accessing rare activities from random RNA sequences: The importance of the length of molecules in the starting pool Chemistry and Biology. 4: 767-774. PMID 9375255  1
1997 Williams KP, Liu XH, Schumacher TNM, Lin HY, Ausiello DA, Kim PS, Bartel DP. Bioactive and nuclease-resistant L-DNA ligand of vasopressin Proceedings of the National Academy of Sciences of the United States of America. 94: 11285-11290. PMID 9326601 DOI: 10.1073/pnas.94.21.11285  1
1996 Rohatgi R, Bartel DP, Szostak JW. Nonenzymatic, template-directed ligation of oligoribonucleotides is highly regioselective for the formation of 3'-5' phosphodiester bonds. Journal of the American Chemical Society. 118: 3340-4. PMID 11539268  1
1996 Rohatgi R, Bartel DP, Szostak JW. Kinetic and mechanistic analysis of nonenzymatic, template-directed oligoribonucleotide ligation. Journal of the American Chemical Society. 118: 3332-9. PMID 11539267 DOI: 10.1021/ja953712b  1
1996 Williams KP, Bartel DP. Phylogenetic analysis of tmRNA secondary structure Rna. 2: 1306-1310. PMID 8972778  1
1996 Ekland EH, Bartel DP. RNA-catalysed RNA polymerization using nucleoside triphosphates Nature. 383: 192. PMID 8774888 DOI: 10.1038/382373a0  1
1995 Ekland EH, Bartel DP. The secondary structure and sequence optimization of an RNA ligase ribozyme Nucleic Acids Research. 23: 3231-3238. PMID 7667099 DOI: 10.1093/nar/23.16.3231  1
1995 Ekland EH, Szostak JW, Bartel DP. Structurally complex and highly active RNA ligases derived from random RNA sequences. Science (New York, N.Y.). 269: 364-70. PMID 7618102  1
1995 Lorsch JR, Bartel DP, Szostak JW. Reverse transcriptase reads through a 2'-5'linkage and a 2'-thiophosphate in a template. Nucleic Acids Research. 23: 2811-4. PMID 7544885 DOI: 10.1093/nar/23.15.2811  1
1995 Williams KP, Bartel DP. PCR product with strands of unequal length Nucleic Acids Research. 23: 4220-4221. PMID 7479087  1
1994 Peterson RD, Bartel DP, Szostak JW, Horvath SJ, Feigon J. 1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element. Biochemistry. 33: 5357-66. PMID 8180157  1
1993 Bartel DP, Szostak JW. Isolation of new ribozymes from a large pool of random sequences [see comment]. Science (New York, N.Y.). 261: 1411-8. PMID 7690155  1
1993 Giver L, Bartel DP, Zapp ML, Green MR, Ellington AD. Selection and design of high-affinity rna ligands for hiv-1 rev Gene. 137: 19-24. PMID 7506689 DOI: 10.1016/0378-1119(93)90246-Y  1
1991 Bartel DP, Doudna JA, Usman N, Szostak JW. Template-directed primer extension catalyzed by the Tetrahymena ribozyme. Molecular and Cellular Biology. 11: 3390-4. PMID 2038341  1
1991 Bartel DP, Zapp ML, Green MR, Szostak JW. HIV-1 Rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA. Cell. 67: 529-36. PMID 1934059  1
1991 Green R, Ellington AD, Bartel DP, Szostak JW. In vitro genetic analysis: Selection and amplification of rare functional nucleic acids Methods. 2: 75-86. DOI: 10.1016/S1046-2023(05)80127-6  1
1989 Michel F, Hanna M, Green R, Bartel DP, Szostak JW. The guanosine binding site of the Tetrahymena ribozyme. Nature. 342: 391-5. PMID 2685606 DOI: 10.1038/342391a0  1
1989 Bartel DP, Sheng M, Lau LF, Greenberg ME. Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction. Genes & Development. 3: 304-13. PMID 2498163  1
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