Jonathan S. Weissman - Publications

Affiliations: 
Cellular and Molecular Pharmacology University of California, San Francisco, San Francisco, CA 
Area:
Proteomics, Protein Folding, and Prion-Based Inheritance in Disease and Normal Biology
Website:
http://profiles.ucsf.edu/jonathan.weissman

216 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Norman TM, Horlbeck MA, Replogle JM, Ge AY, Xu A, Jost M, Gilbert LA, Weissman JS. Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. Science (New York, N.Y.). PMID 31395745 DOI: 10.1126/science.aax4438  0.36
2019 Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. Elife. 8. PMID 31149896 DOI: 10.7554/eLife.46595  0.72
2019 Igbaria A, Merksamer PI, Trusina A, Tilahun F, Johnson JR, Brandman O, Krogan NJ, Weissman JS, Papa FR. Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 31101715 DOI: 10.1073/pnas.1904516116  0.6
2019 Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. Molecular recording of mammalian embryogenesis. Nature. PMID 31086336 DOI: 10.1038/s41586-019-1184-5  0.32
2019 Santos DA, Shi L, Tu BP, Weissman JS. Cycloheximide can distort measurements of mRNA levels and translation efficiency. Nucleic Acids Research. PMID 30916348 DOI: 10.1093/nar/gkz205  1
2019 Liaud N, Horlbeck MA, Gilbert LA, Gjoni K, Weissman JS, Cate JHD. Cellular response to small molecules that selectively stall protein synthesis by the ribosome. Plos Genetics. 15: e1008057. PMID 30875366 DOI: 10.1371/journal.pgen.1008057  0.36
2019 Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, et al. Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids. Molecular Cell. PMID 30846318 DOI: 10.1016/j.molcel.2019.01.036  0.72
2018 Ingolia NT, Hussmann JA, Weissman JS. Ribosome Profiling: Global Views of Translation. Cold Spring Harbor Perspectives in Biology. PMID 30037969 DOI: 10.1101/cshperspect.a032698  1
2018 Horlbeck MA, Xu A, Wang M, Bennett NK, Park CY, Bogdanoff D, Adamson B, Chow ED, Kampmann M, Peterson TR, Nakamura K, Fischbach MA, Weissman JS, Gilbert LA. Mapping the Genetic Landscape of Human Cells. Cell. PMID 30033366 DOI: 10.1016/j.cell.2018.06.010  0.72
2018 Li W, Okreglak V, Peschek J, Kimmig P, Zubradt M, Weissman JS, Walter P. Engineering ER-stress dependent non-conventional mRNA splicing. Elife. 7. PMID 29985129 DOI: 10.7554/eLife.35388  0.68
2018 Shao H, Li X, Moses MA, Gilbert LA, Kalyanaraman C, Young ZT, Chernova M, Journey SN, Weissman JS, Hann B, Jacobson MP, Neckers LM, Gestwicki JE. Exploration of Benzothiazole-Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). Journal of Medicinal Chemistry. PMID 29953808 DOI: 10.1021/acs.jmedchem.8b00583  0.36
2018 Guenther UP, Weinberg DE, Zubradt MM, Tedeschi FA, Stawicki BN, Zagore LL, Brar GA, Licatalosi DD, Bartel DP, Weissman JS, Jankowsky E. The helicase Ded1p controls use of near-cognate translation initiation codons in 5' UTRs. Nature. PMID 29950728 DOI: 10.1038/s41586-018-0258-0  0.84
2018 Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky J, ... ... Weissman JS, et al. The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins. Elife. 7. PMID 29809151 DOI: 10.7554/eLife.37018  0.84
2018 Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates. Elife. 7. PMID 29745899 DOI: 10.7554/eLife.36620  1
2018 Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, ... Weissman JS, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. PMID 29731168 DOI: 10.1016/j.cell.2018.03.068  0.36
2018 Zhang Y, Burkhardt DH, Rouskin S, Li GW, Weissman JS, Gross CA. A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation. Molecular Cell. PMID 29628307 DOI: 10.1016/j.molcel.2018.02.035  0.84
2018 Martinko AJ, Truillet C, Julien O, Diaz J, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans M, Wells JA. Targeting RAS driven human cancer cells with antibodies to upregulated and essential cell-surface proteins. Elife. 7. PMID 29359686 DOI: 10.7554/eLife.31098  0.36
2017 Jost M, Weissman JS. CRISPR approaches to small molecule target identification. Acs Chemical Biology. PMID 29261286 DOI: 10.1021/acschembio.7b00965  0.32
2017 Jost M, Weissman JS. CRISPR approaches to small molecule target identification. Acs Chemical Biology. PMID 29261286 DOI: 10.1021/acschembio.7b00965  0.32
2017 Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell PJ, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Weissman JS, et al. Science Forum: The Human Cell Atlas. Elife. 6. PMID 29206104 DOI: 10.7554/eLife.27041  0.48
2017 Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform. Hepatology (Baltimore, Md.). PMID 29091290 DOI: 10.1002/hep.29626  0.36
2017 Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, Rai A, Cho MY, Stern JJ, Prota AE, Kampmann M, Akhmanova A, Steinmetz MO, Tanenbaum ME, Weissman JS. Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent. Molecular Cell. 68: 210-223.e6. PMID 28985505 DOI: 10.1016/j.molcel.2017.09.012  0.72
2017 Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, Weinberg DE, Weissman JS. CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Science (New York, N.Y.). 357: 414-417. PMID 28751611 DOI: 10.1126/science.aam7787  0.84
2017 Kruth K, Fang M, Shelton DN, Abu-Halawa O, Mahling R, Yang H, Weissman JS, Loh ML, Müschen M, Tasian SK, Bassik MC, Kampmann M, Pufall MA. Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia. Blood. PMID 28424165 DOI: 10.1182/blood-2017-02-766204  0.72
2017 Burkhardt DH, Rouskin S, Zhang Y, Li GW, Weissman JS, Gross CA. Operon mRNAs are organized into ORF-centric structures that predict translation efficiency. Elife. 6. PMID 28139975 DOI: 10.7554/eLife.22037  0.84
2017 Sendoel A, Dunn JG, Rodriguez EH, Naik S, Gomez NC, Hurwitz B, Levorse J, Dill BD, Schramek D, Molina H, Weissman JS, Fuchs E. Translation from unconventional 5' start sites drives tumour initiation. Nature. PMID 28077873 DOI: 10.1038/nature21036  0.8
2017 Stewart-Ornstein J, Chen S, Bhatnagar R, Weissman JS, El-Samad H. Model-guided optogenetic study of PKA signaling in budding yeast. Molecular Biology of the Cell. 28: 221-227. PMID 28035051 DOI: 10.1091/mbc.E16-06-0354  0.64
2016 Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, ... ... Weissman JS, et al. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 167: 1867-1882.e21. PMID 27984733 DOI: 10.1016/j.cell.2016.11.048  0.76
2016 Dixit A, Parnas O, Li B, Chen J, Fulco CP, Jerby-Arnon L, Marjanovic ND, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman TM, Lander ES, Weissman JS, Friedman N, et al. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 167: 1853-1866.e17. PMID 27984732 DOI: 10.1016/j.cell.2016.11.038  0.48
2016 Liu SJ, Horlbeck MA, Cho SW, Birk HS, Malatesta M, He D, Attenello FJ, Villalta JE, Cho MY, Chen Y, Mandegar MA, Olvera MP, Gilbert LA, Conklin BR, Chang HY, ... Weissman JS, et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science (New York, N.Y.). PMID 27980086 DOI: 10.1126/science.aah7111  0.36
2016 Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, ... ... Weissman JS, et al. The mTOR Complex Controls HIV Latency. Cell Host & Microbe. 20: 785-797. PMID 27978436 DOI: 10.1016/j.chom.2016.11.001  0.72
2016 Aviram N, Ast T, Costa EA, Arakel EC, Chuartzman SG, Jan CH, Haßdenteufel S, Dudek J, Jung M, Schorr S, Zimmermann R, Schwappach B, Weissman JS, Schuldiner M. The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. Nature. 540: 134-138. PMID 27905431 DOI: 10.1038/nature20169  0.44
2016 Dunn JG, Weissman JS. Plastid: nucleotide-resolution analysis of next-generation sequencing and genomics data. Bmc Genomics. 17: 958. PMID 27875984 DOI: 10.1186/s12864-016-3278-x  0.56
2016 Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo. Nature Methods. PMID 27819661 DOI: 10.1038/nmeth.4057  0.84
2016 Schrader JM, Li GW, Childers WS, Perez AM, Weissman JS, Shapiro L, McAdams HH. Dynamic translation regulation in Caulobacter cell cycle control. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791168 DOI: 10.1073/pnas.1614795113  0.6
2016 Horlbeck MA, Gilbert LA, Villalta JE, Adamson B, Pak RA, Chen Y, Fields AP, Park CY, Corn JE, Kampmann M, Weissman JS. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 5. PMID 27661255 DOI: 10.7554/eLife.19760  0.72
2016 Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG. Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 27450084 DOI: 10.1073/pnas.1603883113  0.32
2016 Nguyen DP, Miyaoka Y, Gilbert LA, Mayerl SJ, Lee BH, Weissman JS, Conklin BR, Wells JA. Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity. Nature Communications. 7: 12009. PMID 27363581 DOI: 10.1038/ncomms12009  0.36
2016 Liu YC, Fujimori DG, Weissman JS. Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27357682 DOI: 10.1073/pnas.1608795113  1
2016 Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT. Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27325776 DOI: 10.1073/pnas.1600582113  0.36
2016 Leonetti MD, Sekine S, Kamiyama D, Weissman JS, Huang B. A scalable strategy for high-throughput GFP tagging of endogenous human proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 27274053 DOI: 10.1073/pnas.1606731113  0.32
2016 Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CH, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, et al. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. Cell. PMID 27238023 DOI: 10.1016/j.cell.2016.05.003  0.32
2016 Liu SJ, Nowakowski TJ, Pollen AA, Lui JH, Horlbeck MA, Attenello FJ, He D, Weissman JS, Kriegstein AR, Diaz AA, Lim DA. Single-cell analysis of long non-coding RNAs in the developing human neocortex. Genome Biology. 17: 67. PMID 27081004 DOI: 10.1186/s13059-016-0932-1  0.48
2016 Kamiyama D, Sekine S, Barsi-Rhyne B, Hu J, Chen B, Gilbert LA, Ishikawa H, Leonetti MD, Marshall WF, Weissman JS, Huang B. Versatile protein tagging in cells with split fluorescent protein. Nature Communications. 7: 11046. PMID 26988139 DOI: 10.1038/ncomms11046  0.32
2016 Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tijan R, Weissman JS. Nucleosomes impede Cas9 access to DNA in vivo and in vitro. Elife. 5. PMID 26987018 DOI: 10.7554/eLife.12677  0.32
2016 Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, ... ... Weissman JS, et al. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. PMID 26971820 DOI: 10.1016/j.stem.2016.01.022  0.32
2015 Fields AP, Rodriguez EH, Jovanovic M, Stern-Ginossar N, Haas BJ, Mertins P, Raychowdhury R, Hacohen N, Carr SA, Ingolia NT, Regev A, Weissman JS. A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. Molecular Cell. 60: 816-27. PMID 26638175 DOI: 10.1016/j.molcel.2015.11.013  1
2015 Suzuki G, Weissman JS, Tanaka M. [KIL-d] Protein Element Confers Antiviral Activity via Catastrophic Viral Mutagenesis. Molecular Cell. 60: 651-60. PMID 26590718 DOI: 10.1016/j.molcel.2015.10.020  0.48
2015 Anderson DJ, Le Moigne R, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Kiss von Soly S, Madriaga A, Soriano F, Menon MK, Wu ZY, Kampmann M, ... ... Weissman JS, et al. Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis. Cancer Cell. 28: 653-65. PMID 26555175 DOI: 10.1016/j.ccell.2015.10.002  0.32
2015 Brar GA, Weissman JS. Ribosome profiling reveals the what, when, where and how of protein synthesis. Nature Reviews. Molecular Cell Biology. 16: 651-64. PMID 26465719 DOI: 10.1038/nrm4069  0.48
2015 Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I, Choudhary C, Walter P, Weissman JS, Kampmann M. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 4. PMID 26327694 DOI: 10.7554/eLife.08153  1
2015 Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD. Regulation of mRNA translation during mitosis. Elife. 4. PMID 26305499 DOI: 10.7554/eLife.07957  0.32
2015 Kampmann M, Horlbeck MA, Chen Y, Tsai JC, Bassik MC, Gilbert LA, Villalta JE, Kwon SC, Chang H, Kim VN, Weissman JS. Next-generation libraries for robust RNA interference-based genome-wide screens. Proceedings of the National Academy of Sciences of the United States of America. 112: E3384-91. PMID 26080438 DOI: 10.1073/pnas.1508821112  1
2015 Jan CH, Williams CC, Weissman JS. LOCAL TRANSLATION. Response to Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". Science (New York, N.Y.). 348: 1217. PMID 26068842 DOI: 10.1126/science.aaa8299  1
2015 Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, et al. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response. Elife. 4: e07314. PMID 25875391 DOI: 10.7554/eLife.07314  0.72
2015 Kampmann M, Bassik MC, Weissman JS. Corrigendum: functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nature Protocols. 10: 643. PMID 25811902 DOI: 10.1038/nprot0415-644d  0.72
2015 Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, ... ... Weissman JS, et al. Biotechnology. A prudent path forward for genomic engineering and germline gene modification. Science (New York, N.Y.). 348: 36-8. PMID 25791083 DOI: 10.1126/science.aab1028  0.36
2015 Jovanovic M, Rooney MS, Mertins P, Przybylski D, Chevrier N, Satija R, Rodriguez EH, Fields AP, Schwartz S, Raychowdhury R, Mumbach MR, Eisenhaure T, Rabani M, Gennert D, Lu D, ... ... Weissman JS, et al. Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens. Science (New York, N.Y.). 347: 1259038. PMID 25745177 DOI: 10.1126/science.1259038  1
2015 Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M, Walter P, Weissman JS, Sherman MY, Gestwicki JE. Validation of the hsp70-bag3 protein-protein interaction as a potential therapeutic target in cancer. Molecular Cancer Therapeutics. 14: 642-8. PMID 25564440 DOI: 10.1158/1535-7163.MCT-14-0650  0.32
2015 Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Science (New York, N.Y.). 347: 75-8. PMID 25554787 DOI: 10.1126/science.1259724  1
2015 Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell. 160: 339-50. PMID 25533786 DOI: 10.1016/j.cell.2014.11.052  0.32
2014 Pop C, Rouskin S, Ingolia NT, Han L, Phizicky EM, Weissman JS, Koller D. Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation. Molecular Systems Biology. 10: 770. PMID 25538139 DOI: 10.15252/msb.20145524  1
2014 Jan CH, Williams CC, Weissman JS. Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling. Science (New York, N.Y.). 346: 1257521. PMID 25378630 DOI: 10.1126/science.1257521  1
2014 Williams CC, Jan CH, Weissman JS. Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. Science (New York, N.Y.). 346: 748-51. PMID 25378625 DOI: 10.1126/science.1257522  1
2014 Kannan K, Kanabar P, Schryer D, Florin T, Oh E, Bahroos N, Tenson T, Weissman JS, Mankin AS. The general mode of translation inhibition by macrolide antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 111: 15958-63. PMID 25349425 DOI: 10.1073/pnas.1417334111  1
2014 Albert FW, Muzzey D, Weissman JS, Kruglyak L. Genetic influences on translation in yeast. Plos Genetics. 10: e1004692. PMID 25340754 DOI: 10.1371/journal.pgen.1004692  1
2014 Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell. 159: 635-46. PMID 25307933 DOI: 10.1016/j.cell.2014.09.039  1
2014 Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 159: 647-61. PMID 25307932 DOI: 10.1016/j.cell.2014.09.029  1
2014 Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Unraveling the mechanism of cell death induced by chemical fibrils. Nature Chemical Biology. 10: 969-76. PMID 25262416 DOI: 10.1038/nchembio.1639  0.32
2014 Ingolia NT, Brar GA, Stern-Ginossar N, Harris MS, Talhouarne GJ, Jackson SE, Wills MR, Weissman JS. Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. Cell Reports. 8: 1365-79. PMID 25159147 DOI: 10.1016/j.celrep.2014.07.045  1
2014 Smith MH, Rodriguez EH, Weissman JS. Misfolded proteins induce aggregation of the lectin Yos9. The Journal of Biological Chemistry. 289: 25670-7. PMID 25086047 DOI: 10.1074/jbc.M114.583344  1
2014 Schrader JM, Zhou B, Li GW, Lasker K, Childers WS, Williams B, Long T, Crosson S, McAdams HH, Weissman JS, Shapiro L. The coding and noncoding architecture of the Caulobacter crescentus genome. Plos Genetics. 10: e1004463. PMID 25078267 DOI: 10.1371/journal.pgen.1004463  1
2014 Kampmann M, Bassik MC, Weissman JS. Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps. Nature Protocols. 9: 1825-47. PMID 24992097 DOI: 10.1038/nprot.2014.103  1
2014 van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nature Communications. 5: 3832. PMID 24807418 DOI: 10.1038/ncomms4832  1
2014 Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS. A pause sequence enriched at translation start sites drives transcription dynamics in vivo. Science (New York, N.Y.). 344: 1042-7. PMID 24789973 DOI: 10.1126/science.1251871  1
2014 Li GW, Burkhardt D, Gross C, Weissman JS. Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell. 157: 624-35. PMID 24766808 DOI: 10.1016/j.cell.2014.02.033  1
2014 Muzzey D, Sherlock G, Weissman JS. Extensive and coordinated control of allele-specific expression by both transcription and translation in Candida albicans. Genome Research. 24: 963-73. PMID 24732588 DOI: 10.1101/gr.166322.113  1
2014 Wolff S, Weissman JS, Dillin A. Differential scales of protein quality control. Cell. 157: 52-64. PMID 24679526 DOI: 10.1016/j.cell.2014.03.007  1
2014 Arias C, Weisburd B, Stern-Ginossar N, Mercier A, Madrid AS, Bellare P, Holdorf M, Weissman JS, Ganem D. KSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and functional features. Plos Pathogens. 10: e1003847. PMID 24453964 DOI: 10.1371/journal.ppat.1003847  1
2014 Rouskin S, Zubradt M, Washietl S, Kellis M, Weissman JS. Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature. 505: 701-5. PMID 24336214 DOI: 10.1038/nature12894  1
2013 Chen B, Gilbert LA, Cimini BA, Schnitzbauer J, Zhang W, Li GW, Park J, Blackburn EH, Weissman JS, Qi LS, Huang B. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell. 155: 1479-91. PMID 24360272 DOI: 10.1016/j.cell.2013.12.001  0.6
2013 Dunn JG, Foo CK, Belletier NG, Gavis ER, Weissman JS. Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster. Elife. 2: e01179. PMID 24302569 DOI: 10.7554/eLife.01179  1
2013 Stewart-Ornstein J, Nelson C, DeRisi J, Weissman JS, El-Samad H. Msn2 coordinates a stoichiometric gene expression program. Current Biology : Cb. 23: 2336-45. PMID 24210615 DOI: 10.1016/j.cub.2013.09.043  1
2013 Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chemistry & Biology. 20: 1352-63. PMID 24183972 DOI: 10.1016/j.chembiol.2013.09.014  1
2013 Wiita AP, Ziv E, Wiita PJ, Urisman A, Julien O, Burlingame AL, Weissman JS, Wells JA. Global cellular response to chemotherapy-induced apoptosis. Elife. 2: e01236. PMID 24171104 DOI: 10.7554/eLife.01236  1
2013 Becker AH, Oh E, Weissman JS, Kramer G, Bukau B. Selective ribosome profiling as a tool for studying the interaction of chaperones and targeting factors with nascent polypeptide chains and ribosomes. Nature Protocols. 8: 2212-39. PMID 24136347 DOI: 10.1038/nprot.2013.133  1
2013 Larson MH, Gilbert LA, Wang X, Lim WA, Weissman JS, Qi LS. CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nature Protocols. 8: 2180-96. PMID 24136345 DOI: 10.1038/nprot.2013.132  1
2013 Berchowitz LE, Gajadhar AS, van Werven FJ, De Rosa AA, Samoylova ML, Brar GA, Xu Y, Xiao C, Futcher B, Weissman JS, White FM, Amon A. A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern. Genes & Development. 27: 2147-63. PMID 24115771 DOI: 10.1101/gad.224253.113  1
2013 Muzzey D, Schwartz K, Weissman JS, Sherlock G. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biology. 14: R97. PMID 24025428 DOI: 10.1186/gb-2013-14-9-r97  1
2013 Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell. 154: 442-51. PMID 23849981 DOI: 10.1016/j.cell.2013.06.044  0.84
2013 Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. Genome-wide annotation and quantitation of translation by ribosome profiling. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 4.18. PMID 23821443 DOI: 10.1002/0471142727.mb0418s103  1
2013 Guttman M, Russell P, Ingolia NT, Weissman JS, Lander ES. Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. Cell. 154: 240-51. PMID 23810193 DOI: 10.1016/j.cell.2013.06.009  1
2013 Kampmann M, Bassik MC, Weissman JS. Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E2317-26. PMID 23739767 DOI: 10.1073/pnas.1307002110  1
2013 O'Connor PB, Li GW, Weissman JS, Atkins JF, Baranov PV. rRNA:mRNA pairing alters the length and the symmetry of mRNA-protected fragments in ribosome profiling experiments. Bioinformatics (Oxford, England). 29: 1488-91. PMID 23603333 DOI: 10.1093/bioinformatics/btt184  1
2013 Thorburn RR, Gonzalez C, Brar GA, Christen S, Carlile TM, Ingolia NT, Sauer U, Weissman JS, Amon A. Aneuploid yeast strains exhibit defects in cell growth and passage through START. Molecular Biology of the Cell. 24: 1274-89. PMID 23468524 DOI: 10.1091/mbc.E12-07-0520  1
2013 Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell. 152: 1173-83. PMID 23452860 DOI: 10.1016/j.cell.2013.02.022  0.36
2013 Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 152: 909-22. PMID 23394947 DOI: 10.1016/j.cell.2013.01.030  1
2013 Schuldiner M, Weissman JS. The contribution of systematic approaches to characterizing the proteins and functions of the endoplasmic reticulum. Cold Spring Harbor Perspectives in Biology. 5: a013284. PMID 23359093 DOI: 10.1101/cshperspect.a013284  1
2012 Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein MY, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman JS. Decoding human cytomegalovirus. Science (New York, N.Y.). 338: 1088-93. PMID 23180859 DOI: 10.1126/science.1227919  1
2012 Brandman O, Stewart-Ornstein J, Wong D, Larson A, Williams CC, Li GW, Zhou S, King D, Shen PS, Weibezahn J, Dunn JG, Rouskin S, Inada T, Frost A, Weissman JS. A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress. Cell. 151: 1042-54. PMID 23178123 DOI: 10.1016/j.cell.2012.10.044  1
2012 Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nature Protocols. 7: 1534-50. PMID 22836135 DOI: 10.1038/nprot.2012.086  1
2012 Carvunis AR, Rolland T, Wapinski I, Calderwood MA, Yildirim MA, Simonis N, Charloteaux B, Hidalgo CA, Barbette J, Santhanam B, Brar GA, Weissman JS, Regev A, Thierry-Mieg N, Cusick ME, et al. Proto-genes and de novo gene birth. Nature. 487: 370-4. PMID 22722833 DOI: 10.1038/nature11184  1
2012 Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein MY, Poser I, Mann M, Hyman AA, Weissman JS. Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell. 149: 1339-52. PMID 22682253 DOI: 10.1016/j.cell.2012.04.028  1
2012 Radford SE, Weissman JS. Special issue: the molecular and cellular mechanisms of amyloidosis. Journal of Molecular Biology. 421: 139-41. PMID 22664198 DOI: 10.1016/j.jmb.2012.05.042  1
2012 Churchman LS, Weissman JS. Native elongating transcript sequencing (NET-seq). Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 4.14.1-17. PMID 22470065 DOI: 10.1002/0471142727.mb0414s98  1
2012 Li GW, Oh E, Weissman JS. The anti-Shine-Dalgarno sequence drives translational pausing and codon choice in bacteria. Nature. 484: 538-41. PMID 22456704 DOI: 10.1038/nature10965  1
2012 Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, ... Weissman JS, et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 485: 55-61. PMID 22367541 DOI: 10.1038/nature10912  1
2012 Stewart-Ornstein J, Weissman JS, El-Samad H. Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae. Molecular Cell. 45: 483-93. PMID 22365828 DOI: 10.1016/j.molcel.2011.11.035  1
2012 Brar GA, Yassour M, Friedman N, Regev A, Ingolia NT, Weissman JS. High-resolution view of the yeast meiotic program revealed by ribosome profiling. Science (New York, N.Y.). 335: 552-7. PMID 22194413 DOI: 10.1126/science.1215110  1
2011 El-Samad H, Weissman JS. Genetics: Noise rules. Nature. 480: 188-9. PMID 22158239 DOI: 10.1038/480188a  1
2011 Oh E, Becker AH, Sandikci A, Huber D, Chaba R, Gloge F, Nichols RJ, Typas A, Gross CA, Kramer G, Weissman JS, Bukau B. Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo. Cell. 147: 1295-308. PMID 22153074 DOI: 10.1016/j.cell.2011.10.044  1
2011 Smith MH, Ploegh HL, Weissman JS. Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science (New York, N.Y.). 334: 1086-90. PMID 22116878 DOI: 10.1126/science.1209235  1
2011 Roelants FM, Breslow DK, Muir A, Weissman JS, Thorner J. Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 108: 19222-7. PMID 22080611 DOI: 10.1073/pnas.1116948108  1
2011 Ingolia NT, Lareau LF, Weissman JS. Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell. 147: 789-802. PMID 22056041 DOI: 10.1016/j.cell.2011.10.002  1
2011 Hoppins S, Collins SR, Cassidy-Stone A, Hummel E, Devay RM, Lackner LL, Westermann B, Schuldiner M, Weissman JS, Nunnari J. A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. The Journal of Cell Biology. 195: 323-40. PMID 21987634 DOI: 10.1083/jcb.201107053  0.88
2011 Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature. 476: 88-91. PMID 21814281 DOI: 10.1038/nature10245  1
2011 Terzi N, Churchman LS, Vasiljeva L, Weissman J, Buratowski S. H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway. Molecular and Cellular Biology. 31: 3569-83. PMID 21709022 DOI: 10.1128/MCB.05590-11  1
2011 Toyama BH, Weissman JS. Amyloid structure: conformational diversity and consequences. Annual Review of Biochemistry. 80: 557-85. PMID 21456964 DOI: 10.1146/annurev-biochem-090908-120656  1
2011 Verges KJ, Smith MH, Toyama BH, Weissman JS. Strain conformation, primary structure and the propagation of the yeast prion [PSI+]. Nature Structural & Molecular Biology. 18: 493-9. PMID 21423194 DOI: 10.1038/nsmb.2030  1
2011 Foo CK, Ohhashi Y, Kelly MJ, Tanaka M, Weissman JS. Radically different amyloid conformations dictate the seeding specificity of a chimeric Sup35 prion. Journal of Molecular Biology. 408: 1-8. PMID 21333653 DOI: 10.1016/j.jmb.2011.02.025  1
2011 Churchman LS, Weissman JS. Nascent transcript sequencing visualizes transcription at nucleotide resolution. Nature. 469: 368-73. PMID 21248844 DOI: 10.1038/nature09652  1
2011 Henry TC, Power JE, Kerwin CL, Mohammed A, Weissman JS, Cameron DM, Wykoff DD. Systematic screen of Schizosaccharomyces pombe deletion collection uncovers parallel evolution of the phosphate signal transduction pathway in yeasts. Eukaryotic Cell. 10: 198-206. PMID 21169418 DOI: 10.1128/EC.00216-10  1
2010 Weissman JS. The epistemology of cell biology. Molecular Biology of the Cell. 21: 3825. PMID 21079033 DOI: 10.1091/mbc.E10-04-0370  1
2010 Breslow DK, Weissman JS. Membranes in balance: mechanisms of sphingolipid homeostasis. Molecular Cell. 40: 267-79. PMID 20965421 DOI: 10.1016/j.molcel.2010.10.005  1
2010 Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 466: 835-40. PMID 20703300 DOI: 10.1038/nature09267  1
2010 Battle A, Jonikas MC, Walter P, Weissman JS, Koller D. Automated identification of pathways from quantitative genetic interaction data. Molecular Systems Biology. 6: 379. PMID 20531408 DOI: 10.1038/msb.2010.27  1
2010 Springer M, Weissman JS, Kirschner MW. A general lack of compensation for gene dosage in yeast. Molecular Systems Biology. 6: 368. PMID 20461075 DOI: 10.1038/msb.2010.19  1
2010 Vembar SS, Jonikas MC, Hendershot LM, Weissman JS, Brodsky JL. J domain co-chaperone specificity defines the role of BiP during protein translocation. The Journal of Biological Chemistry. 285: 22484-94. PMID 20430885 DOI: 10.1074/jbc.M110.102186  1
2010 Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D. Molecular basis of infrared detection by snakes. Nature. 464: 1006-11. PMID 20228791 DOI: 10.1038/nature08943  1
2010 Breslow DK, Collins SR, Bodenmiller B, Aebersold R, Simons K, Shevchenko A, Ejsing CS, Weissman JS. Orm family proteins mediate sphingolipid homeostasis. Nature. 463: 1048-53. PMID 20182505 DOI: 10.1038/nature08787  1
2010 Ohhashi Y, Ito K, Toyama BH, Weissman JS, Tanaka M. Differences in prion strain conformations result from non-native interactions in a nucleus. Nature Chemical Biology. 6: 225-230. PMID 20081853 DOI: 10.1038/nchembio.306  1
2009 Collins SR, Weissman JS, Krogan NJ. From information to knowledge: new technologies for defining gene function. Nature Methods. 6: 721-23. PMID 19953683 DOI: 10.1038/nmeth1009-721  1
2009 Weissman J. Journal club. A biochemist looks at how DNA sequencing can reveal more than just sequences Nature. 461: 1177. PMID 19865125  1
2009 Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. The Journal of Cell Biology. 186: 323-31. PMID 19651891 DOI: 10.1083/jcb.200903014  1
2009 Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science (New York, N.Y.). 325: 477-81. PMID 19556461 DOI: 10.1126/science.1175088  0.88
2009 Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nature Methods. 6: 443-5. PMID 19448642 DOI: 10.1038/nmeth.1330  1
2009 Passos DO, Doma MK, Shoemaker CJ, Muhlrad D, Green R, Weissman J, Hollien J, Parker R. Analysis of Dom34 and its function in no-go decay. Molecular Biology of the Cell. 20: 3025-32. PMID 19420139 DOI: 10.1091/mbc.E09-01-0028  1
2009 Jonikas MC, Collins SR, Denic V, Oh E, Quan EM, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman JS, Schuldiner M. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science (New York, N.Y.). 323: 1693-7. PMID 19325107 DOI: 10.1126/science.1167983  1
2009 Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, et al. Functional organization of the S. cerevisiae phosphorylation network. Cell. 136: 952-63. PMID 19269370 DOI: 10.1016/j.cell.2008.12.039  0.88
2009 Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science (New York, N.Y.). 324: 218-23. PMID 19213877 DOI: 10.1126/science.1168978  1
2008 Typas A, Nichols RJ, Siegele DA, Shales M, Collins SR, Lim B, Braberg H, Yamamoto N, Takeuchi R, Wanner BL, Mori H, Weissman JS, Krogan NJ, Gross CA. High-throughput, quantitative analyses of genetic interactions in E. coli. Nature Methods. 5: 781-7. PMID 19160513 DOI: 10.1038/nmeth.1240  1
2008 Quan EM, Kamiya Y, Kamiya D, Denic V, Weibezahn J, Kato K, Weissman JS. Defining the glycan destruction signal for endoplasmic reticulum-associated degradation. Molecular Cell. 32: 870-7. PMID 19111666 DOI: 10.1016/j.molcel.2008.11.017  1
2008 Wilmes GM, Bergkessel M, Bandyopadhyay S, Shales M, Braberg H, Cagney G, Collins SR, Whitworth GB, Kress TL, Weissman JS, Ideker T, Guthrie C, Krogan NJ. A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Molecular Cell. 32: 735-46. PMID 19061648 DOI: 10.1016/j.molcel.2008.11.012  1
2008 Tipton KA, Verges KJ, Weissman JS. In vivo monitoring of the prion replication cycle reveals a critical role for Sis1 in delivering substrates to Hsp104. Molecular Cell. 32: 584-91. PMID 19026788 DOI: 10.1016/j.molcel.2008.11.003  1
2008 Chechik G, Oh E, Rando O, Weissman J, Regev A, Koller D. Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network. Nature Biotechnology. 26: 1251-9. PMID 18953355 DOI: 10.1038/nbt.1499  1
2008 Roguev A, Bandyopadhyay S, Zofall M, Zhang K, Fischer T, Collins SR, Qu H, Shales M, Park HO, Hayles J, Hoe KL, Kim DU, Ideker T, Grewal SI, Weissman JS, et al. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Science (New York, N.Y.). 322: 405-10. PMID 18818364 DOI: 10.1126/science.1162609  1
2008 Ingolia NT, Weissman JS. Systems biology: Reverse engineering the cell. Nature. 454: 1059-62. PMID 18756243 DOI: 10.1038/4541059a  1
2008 Schuldiner M, Metz J, Schmid V, Denic V, Rakwalska M, Schmitt HD, Schwappach B, Weissman JS. The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell. 134: 634-45. PMID 18724936 DOI: 10.1016/j.cell.2008.06.025  1
2008 Breslow DK, Cameron DM, Collins SR, Schuldiner M, Stewart-Ornstein J, Newman HW, Braun S, Madhani HD, Krogan NJ, Weissman JS. A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nature Methods. 5: 711-8. PMID 18622397 DOI: 10.1038/nmeth.1234  1
2008 Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. Small-molecule aggregates inhibit amyloid polymerization. Nature Chemical Biology. 4: 197-9. PMID 18223646 DOI: 10.1038/nchembio.65  1
2008 McDonald M, Kendall A, Tanaka M, Weissman JS, Stubbs G. Enclosed chambers for humidity control and sample containment in fiber diffraction Journal of Applied Crystallography. 41: 206-209. DOI: 10.1107/S0021889807060803  1
2008 Osherovich LZ, Weissman JS. Insights into the Nature of Yeast Prions Protein Folding Handbook. 3: 1144-1174. DOI: 10.1002/9783527619498.ch68  1
2007 Haass FA, Jonikas M, Walter P, Weissman JS, Jan YN, Jan LY, Schuldiner M. Identification of yeast proteins necessary for cell-surface function of a potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 104: 18079-84. PMID 17989219 DOI: 10.1073/pnas.0708765104  1
2007 Roguev A, Wiren M, Weissman JS, Krogan NJ. High-throughput genetic interaction mapping in the fission yeast Schizosaccharomyces pombe. Nature Methods. 4: 861-6. PMID 17893680 DOI: 10.1038/nmeth1098  1
2007 Toyama BH, Kelly MJ, Gross JD, Weissman JS. The structural basis of yeast prion strain variants. Nature. 449: 233-7. PMID 17767153 DOI: 10.1038/nature06108  1
2007 Denic V, Weissman JS. A molecular caliper mechanism for determining very long-chain fatty acid length. Cell. 130: 663-77. PMID 17719544 DOI: 10.1016/j.cell.2007.06.031  1
2007 Morrison AJ, Kim JA, Person MD, Highland J, Xiao J, Wehr TS, Hensley S, Bao Y, Shen J, Collins SR, Weissman JS, Delrow J, Krogan NJ, Haber JE, Shen X. Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses. Cell. 130: 499-511. PMID 17693258 DOI: 10.1016/j.cell.2007.06.010  1
2007 Ihmels J, Collins SR, Schuldiner M, Krogan NJ, Weissman JS. Backup without redundancy: genetic interactions reveal the cost of duplicate gene loss. Molecular Systems Biology. 3: 86. PMID 17389874 DOI: 10.1038/msb4100127  1
2007 Laribee RN, Shibata Y, Mersman DP, Collins SR, Kemmeren P, Roguev A, Weissman JS, Briggs SD, Krogan NJ, Strahl BD. CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proceedings of the National Academy of Sciences of the United States of America. 104: 5836-41. PMID 17389396 DOI: 10.1073/pnas.0607996104  1
2007 Collins SR, Miller KM, Maas NL, Roguev A, Fillingham J, Chu CS, Schuldiner M, Gebbia M, Recht J, Shales M, Ding H, Xu H, Han J, Ingvarsdottir K, Cheng B, ... ... Weissman JS, et al. Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature. 446: 806-10. PMID 17314980 DOI: 10.1038/nature05649  1
2007 Collins SR, Kemmeren P, Zhao XC, Greenblatt JF, Spencer F, Holstege FC, Weissman JS, Krogan NJ. Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Molecular & Cellular Proteomics : McP. 6: 439-50. PMID 17200106 DOI: 10.1074/mcp.M600381-MCP200  1
2006 Schuldiner M, Collins SR, Weissman JS, Krogan NJ. Quantitative genetic analysis in Saccharomyces cerevisiae using epistatic miniarray profiles (E-MAPs) and its application to chromatin functions. Methods (San Diego, Calif.). 40: 344-52. PMID 17101447 DOI: 10.1016/j.ymeth.2006.07.034  1
2006 Tanaka M, Weissman JS. An efficient protein transformation protocol for introducing prions into yeast. Methods in Enzymology. 412: 185-200. PMID 17046659 DOI: 10.1016/S0076-6879(06)12012-1  0.68
2006 Denic V, Quan EM, Weissman JS. A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation. Cell. 126: 349-59. PMID 16873065 DOI: 10.1016/j.cell.2006.05.045  1
2006 Collins SR, Schuldiner M, Krogan NJ, Weissman JS. A strategy for extracting and analyzing large-scale quantitative epistatic interaction data. Genome Biology. 7: R63. PMID 16859555 DOI: 10.1186/gb-2006-7-7-r63  1
2006 Tanaka M, Collins SR, Toyama BH, Weissman JS. The physical basis of how prion conformations determine strain phenotypes. Nature. 442: 585-9. PMID 16810177 DOI: 10.1038/nature04922  1
2006 Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature. 441: 840-6. PMID 16699522 DOI: 10.1038/nature04785  1
2006 Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, ... ... Weissman JS, et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 440: 637-43. PMID 16554755 DOI: 10.1038/nature04670  1
2006 Kulp MS, Frickel EM, Ellgaard L, Weissman JS. Domain architecture of protein-disulfide isomerase facilitates its dual role as an oxidase and an isomerase in Ero1p-mediated disulfide formation. The Journal of Biological Chemistry. 281: 876-84. PMID 16368681 DOI: 10.1074/jbc.M511764200  1
2005 Howson R, Huh WK, Ghaemmaghami S, Falvo JV, Bower K, Belle A, Dephoure N, Wykoff DD, Weissman JS, O'Shea EK. Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. Comparative and Functional Genomics. 6: 2-16. PMID 18629296 DOI: 10.1002/cfg.449  1
2005 Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, et al. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell. 123: 593-605. PMID 16286008 DOI: 10.1016/j.cell.2005.10.025  1
2005 Schuldiner M, Collins SR, Thompson NJ, Denic V, Bhamidipati A, Punna T, Ihmels J, Andrews B, Boone C, Greenblatt JF, Weissman JS, Krogan NJ. Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell. 123: 507-19. PMID 16269340 DOI: 10.1016/j.cell.2005.08.031  1
2005 Bhamidipati A, Denic V, Quan EM, Weissman JS. Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen. Molecular Cell. 19: 741-51. PMID 16168370 DOI: 10.1016/j.molcel.2005.07.027  1
2005 Tanaka M, Chien P, Yonekura K, Weissman JS. Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins. Cell. 121: 49-62. PMID 15820678 DOI: 10.1016/j.cell.2005.03.008  1
2004 Weissman JS, O'Shea EK. 2004 Irving Sigal Young Investigator Award. Protein Science : a Publication of the Protein Society. 13: 3333-5. PMID 15557272 DOI: 10.1110/ps.041134604  1
2004 Collins SR, Douglass A, Vale RD, Weissman JS. Mechanism of prion propagation: amyloid growth occurs by monomer addition. Plos Biology. 2: e321. PMID 15383837 DOI: 10.1371/journal.pbio.0020321  1
2004 Chien P, Weissman JS, DePace AH. Emerging principles of conformation-based prion inheritance. Annual Review of Biochemistry. 73: 617-56. PMID 15189155 DOI: 10.1146/annurev.biochem.72.121801.161837  1
2004 Osherovich LZ, Cox BS, Tuite MF, Weissman JS. Dissection and design of yeast prions. Plos Biology. 2: E86. PMID 15045026 DOI: 10.1371/journal.pbio.0020086  1
2004 Tanaka M, Chien P, Naber N, Cooke R, Weissman JS. Conformational variations in an infectious protein determine prion strain differences. Nature. 428: 323-8. PMID 15029196 DOI: 10.1038/nature02392  1
2004 Tu BP, Weissman JS. Oxidative protein folding in eukaryotes: mechanisms and consequences. The Journal of Cell Biology. 164: 341-6. PMID 14757749 DOI: 10.1083/jcb.200311055  1
2003 Ghaemmaghami S, Huh WK, Bower K, Howson RW, Belle A, Dephoure N, O'Shea EK, Weissman JS. Global analysis of protein expression in yeast. Nature. 425: 737-41. PMID 14562106 DOI: 10.1038/nature02046  1
2003 Huh WK, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. Global analysis of protein localization in budding yeast. Nature. 425: 686-91. PMID 14562095 DOI: 10.1038/nature02026  1
2003 Chien P, DePace AH, Collins SR, Weissman JS. Generation of prion transmission barriers by mutational control of amyloid conformations. Nature. 424: 948-51. PMID 12931190 DOI: 10.1038/nature01894  1
2002 Wang JD, Herman C, Tipton KA, Gross CA, Weissman JS. Directed evolution of substrate-optimized GroEL/S chaperonins. Cell. 111: 1027-39. PMID 12507429 DOI: 10.1016/S0092-8674(02)01198-4  1
2002 Tu BP, Weissman JS. The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum. Molecular Cell. 10: 983-94. PMID 12453408 DOI: 10.1016/S1097-2765(02)00696-2  1
2002 DePace AH, Weissman JS. Origins and kinetic consequences of diversity in Sup35 yeast prion fibers. Nature Structural Biology. 9: 389-96. PMID 11938354 DOI: 10.1038/nsb786  1
2002 Osherovich LZ, Weissman JS. The utility of prions. Developmental Cell. 2: 143-51. PMID 11832240 DOI: 10.1016/S1534-5807(02)00118-1  1
2001 Travers KJ, Patil CK, Weissman JS. Functional genomic approaches to understanding molecular chaperones and stress responses. Advances in Protein Chemistry. 59: 345-90. PMID 11868277 DOI: 10.1016/S0065-3233(01)59011-7  1
2001 Fewell SW, Travers KJ, Weissman JS, Brodsky JL. The action of molecular chaperones in the early secretory pathway. Annual Review of Genetics. 35: 149-91. PMID 11700281 DOI: 10.1146/annurev.genet.35.102401.090313  1
2001 Osherovich LZ, Weissman JS. Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion. Cell. 106: 183-94. PMID 11511346 DOI: 10.1016/S0092-8674(01)00440-8  1
2001 Chien P, Weissman JS. Conformational diversity in a yeast prion dictates its seeding specificity. Nature. 410: 223-7. PMID 11242084 DOI: 10.1038/35065632  1
2000 Tu BP, Ho-Schleyer SC, Travers KJ, Weissman JS. Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science (New York, N.Y.). 290: 1571-4. PMID 11090354  1
2000 Sparrer HE, Santoso A, Szoka FC, Weissman JS. Evidence for the prion hypothesis: induction of the yeast [PSI+] factor by in vitro- converted Sup35 protein. Science (New York, N.Y.). 289: 595-9. PMID 10915616 DOI: 10.1126/science.289.5479.595  1
2000 Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, Walter P. Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell. 101: 249-58. PMID 10847680  1
2000 Santoso A, Chien P, Osherovich LZ, Weissman JS. Molecular basis of a yeast prion species barrier. Cell. 100: 277-88. PMID 10660050  1
1999 Wang JD, Weissman JS. Thinking outside the box: new insights into the mechanism of GroEL-mediated protein folding. Nature Structural Biology. 6: 597-600. PMID 10404205 DOI: 10.1038/10636  1
1998 Wang JD, Michelitsch MD, Weissman JS. GroEL-GroES-mediated protein folding requires an intact central cavity. Proceedings of the National Academy of Sciences of the United States of America. 95: 12163-8. PMID 9770457 DOI: 10.1073/pnas.95.21.12163  1
1998 Pollard MG, Travers KJ, Weissman JS. Ero1p: a novel and ubiquitous protein with an essential role in oxidative protein folding in the endoplasmic reticulum. Molecular Cell. 1: 171-82. PMID 9659914  1
1998 DePace AH, Santoso A, Hillner P, Weissman JS. A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion. Cell. 93: 1241-52. PMID 9657156 DOI: 10.1016/S0092-8674(00)81467-1  1
1998 Horwich AL, Burston SG, Rye HS, Weissman JS, Fenton WA. Construction of single-ring and two-ring hybrid versions of bacterial chaperonin GroEL. Methods in Enzymology. 290: 141-6. PMID 9534157 DOI: 10.1016/S0076-6879(98)90013-1  1
1997 Horwich AL, Weissman JS. Deadly conformations--protein misfolding in prion disease. Cell. 89: 499-510. PMID 9160742  1
1996 Fenton WA, Weissman JS, Horwich AL. Putting a lid on protein folding: structure and function of the co-chaperonin, GroES. Chemistry & Biology. 3: 157-61. PMID 8807841  0.96
1996 Burston SG, Weissman JS, Farr GW, Fenton WA, Horwich AL. Release of both native and non-native proteins from a cis-only GroEL ternary complex. Nature. 383: 96-9. PMID 8779722 DOI: 10.1038/383096a0  1
1996 Weissman JS, Rye HS, Fenton WA, Beechem JM, Horwich AL. Characterization of the active intermediate of a GroEL-GroES-mediated protein folding reaction. Cell. 84: 481-90. PMID 8608602 DOI: 10.1016/S0092-8674(00)81293-3  1
1995 Weissman JS, Kim PS. A kinetic explanation for the rearrangement pathway of BPTI folding. Nature Structural Biology. 2: 1123-30. PMID 8846225  0.96
1995 Horwich AL, Weissman JS, Fenton WA. Kinesis of polypeptide during GroEL-mediated folding. Cold Spring Harbor Symposia On Quantitative Biology. 60: 435-40. PMID 8824417  1
1995 Weissman JS, Sigler PB, Horwich AL. From the cradle to the grave: ring complexes in the life of a protein. Science (New York, N.Y.). 268: 523-4. PMID 7725096  1
1995 Weissman JS, Hohl CM, Kovalenko O, Kashi Y, Chen S, Braig K, Saibil HR, Fenton WA, Horwich AL. Mechanism of GroEL action: productive release of polypeptide from a sequestered position under GroES. Cell. 83: 577-87. PMID 7585961 DOI: 10.1016/0092-8674(95)90098-5  1
1995 Yu MH, Weissman JS, Kim PS. Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. Journal of Molecular Biology. 249: 388-97. PMID 7540212 DOI: 10.1006/jmbi.1995.0304  1
1994 Weissman JS, Kashi Y, Fenton WA, Horwich AL. GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms. Cell. 78: 693-702. PMID 7915201 DOI: 10.1016/0092-8674(94)90533-9  1
1994 Craig EA, Weissman JS, Horwich AL. Heat shock proteins and molecular chaperones: mediators of protein conformation and turnover in the cell. Cell. 78: 365-72. PMID 7914834  1
1993 Weissman JS, Kim PS. Efficient catalysis of disulphide bond rearrangements by protein disulphide isomerase. Nature. 365: 185-8. PMID 7690463 DOI: 10.1038/365185a0  0.96
1992 Weissman JS, Kim PS. Response. Science (New York, N.Y.). 256: 112-4. PMID 17802598 DOI: 10.1126/science.256.5053.112  0.96
1992 Weissman JS, Kim PS. The pro region of BPTI facilitates folding. Cell. 71: 841-51. PMID 1384990  0.96
1992 Weissman JS, Kim PS. Kinetic role of nonnative species in the folding of bovine pancreatic trypsin inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 89: 9900-4. PMID 1384063  0.96
1991 Weissman JS, Kim PS. Reexamination of the folding of BPTI: predominance of native intermediates. Science (New York, N.Y.). 253: 1386-93. PMID 1716783  0.96
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