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Craig J. Forsyth - Publications

Affiliations: 
Chemistry & Biochemistry Ohio State University, Columbus, Columbus, OH 
Area:
Synthetic Organic Chemistry and Chemical Biology
Website:
http://chemistry.osu.edu/faculty/forsyth
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Itskanov S, Wang L, Junne T, Sherriff R, Xiao L, Blanchard N, Shi WQ, Forsyth C, Hoepfner D, Spiess M, Park E. A common mechanism of Sec61 translocon inhibition by small molecules. Nature Chemical Biology. PMID 37169959 DOI: 10.1038/s41589-023-01337-y  0.318
2019 Okumu AA, Forsyth CJ. Synthesis of the C1-C19 Domain of Azaspiracid-34. Organic Letters. PMID 30601015 DOI: 10.1021/Acs.Orglett.8B03451  0.432
2018 Kenton NT, Adu‐Ampratwum D, Okumu AA, Zhang Z, Chen Y, Nguyen S, Xu J, Ding Y, McCarron P, Kilcoyne J, Rise F, Wilkins AL, Miles CO, Forsyth CJ. Total Synthesis of (6 R ,10 R ,13 R ,14 R ,16 R ,17 R ,19 S ,20 R ,21 R ,24 S , 25 S ,28 S ,30 S ,32 R ,33 R ,34 R ,36 S ,37 S ,39 R )‐Azaspiracid‐3 Reveals Non‐Identity with the Natural Product Angewandte Chemie. 130: 805-809. DOI: 10.1002/Ange.201711006  0.738
2017 Kenton NT, Adu-Ampratwum D, Okumu AA, Zhang Z, Chen Y, Nguyen S, Xu J, Ding Y, McCarron P, Kilcoyne J, Rise F, Wilkins AL, Miles CO, Forsyth CJ. Total Synthesis of (6R,10R,13R,14R,16R,17R,19S,20R,21R,24S, 25S,28S,30S,32R,33R,34R,36S,37S,39R)-Azaspiracid-3 Reveals Non-Identity with the Natural Product. Angewandte Chemie (International Ed. in English). PMID 29193614 DOI: 10.1002/Anie.201711006  0.703
2017 Kenton NT, Adu-Ampratwum D, Okumu AA, McCarron P, Kilcoyne J, Rise F, Wilkins AL, Miles CO, Forsyth CJ. Stereochemical Definition of the Natural Product (6R,10R,13R, 14R,16R,17R,19S,20S,21R,24S,25S,28S,30S,32R,33R,34R,36S,37S,39R)-Azaspiracid-3 by Total Synthesis and Comparative Analyses. Angewandte Chemie (International Ed. in English). PMID 29193497 DOI: 10.1002/Anie.201711008  0.768
2017 Akwaboah DC, Wu D, Forsyth CJ. Stereoselective Synthesis of the C1-C9 and C11-C25 Fragments of Amphidinolides C, C2, C3, and F. Organic Letters. PMID 28231009 DOI: 10.1021/Acs.Orglett.7B00217  0.58
2016 Twiner MJ, Doucette GJ, Pang Y, Fang C, Forsyth CJ, Miles CO. Structure-Activity Relationship Studies Using Natural and Synthetic Okadaic Acid/Dinophysistoxin Toxins. Marine Drugs. 14. PMID 27827901 DOI: 10.3390/Md14110207  0.662
2016 Line N, Burns A, Butler S, Cashbolm J, Forsyth CJ. Total Synthesis of (-)-Salvinorin A. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27758012 DOI: 10.1002/Chem.201604853  0.427
2016 Zhang Z, Chen Y, Adu-Ampratwum D, Okumu AA, Kenton NT, Forsyth CJ. Synthesis of the C22-C40 Domain of the Azaspiracids. Organic Letters. PMID 27043010 DOI: 10.1021/Acs.Orglett.6B00557  0.763
2015 Samdal IA, Løvberg KE, Briggs LR, Kilcoyne J, Xu J, Forsyth CJ, Miles CO. Development of an ELISA for the Detection of Azaspiracids. Journal of Agricultural and Food Chemistry. 63: 7855-61. PMID 26245830 DOI: 10.1021/Acs.Jafc.5B02513  0.731
2013 Zhang Z, Ding Y, Xu J, Chen Y, Forsyth CJ. Synthesis of the C1-C21 domain of azaspiracids-1 and -3. Organic Letters. 15: 2338-41. PMID 23627769 DOI: 10.1021/Ol400487E  0.756
2013 Butler SC, Forsyth CJ. A stereoconvergent intramolecular Diels-Alder cycloaddition related to the construction of the decalin core of neo-clerodane diterpenoids. The Journal of Organic Chemistry. 78: 3895-907. PMID 23510204 DOI: 10.1021/Jo400029U  0.393
2013 Wu D, Forsyth CJ. Syntheses of the C1-C14 and C15-C25 fragments of amphidinolide C. Organic Letters. 15: 1178-81. PMID 23441846 DOI: 10.1021/Ol303515H  0.523
2011 Pang Y, Fang C, Twiner MJ, Miles CO, Forsyth CJ. Total synthesis of dinophysistoxin-2 and 2-epi-dinophysistoxin-2 and their PPase inhibition. Angewandte Chemie (International Ed. in English). 50: 7631-5. PMID 21726026 DOI: 10.1002/Anie.201101741  0.642
2011 Wang B, Huang PH, Chen CS, Forsyth CJ. Total syntheses of the histone deacetylase inhibitors largazole and 2-epi-largazole: application of N-heterocyclic carbene mediated acylations in complex molecule synthesis. The Journal of Organic Chemistry. 76: 1140-50. PMID 21244075 DOI: 10.1021/Jo102478X  0.476
2011 Wang B, Hansen TM, Wang T, Wu D, Weyer L, Ying L, Engler MM, Sanville M, Leitheiser C, Christmann M, Lu Y, Chen J, Zunker N, Cink RD, Ahmed F, ... ... Forsyth CJ, et al. Total synthesis of phorboxazole A via de novo oxazole formation: strategy and component assembly. Journal of the American Chemical Society. 133: 1484-505. PMID 21190385 DOI: 10.1021/Ja108906E  0.746
2011 Wang B, Hansen TM, Weyer L, Wu D, Wang T, Christmann M, Lu Y, Ying L, Engler MM, Cink RD, Lee CS, Ahmed F, Forsyth CJ. Total synthesis of phorboxazole A via de novo oxazole formation: convergent total synthesis. Journal of the American Chemical Society. 133: 1506-16. PMID 21190384 DOI: 10.1021/Ja1089099  0.789
2010 Fang C, Pang Y, Forsyth CJ. Formal total synthesis of okadaic acid via regiocontrolled gold(I)-catalyzed spiroketalizations. Organic Letters. 12: 4528-31. PMID 20849144 DOI: 10.1021/Ol101833H  0.693
2010 SABES SF, URBANEK RA, FORSYTH CJ. ChemInform Abstract: Efficient Synthesis of Okadaic Acid. Part 2. Synthesis of C1-C14 Domain and Completion of the Total Synthesis. Cheminform. 29: no-no. DOI: 10.1002/chin.199829325  0.364
2010 URBANEK RA, SABES SF, FORSYTH CJ. ChemInform Abstract: Efficient Synthesis of Okadaic Acid. Part 1. Convergent Assembly of the C15-C38 Domain. Cheminform. 29: no-no. DOI: 10.1002/chin.199829324  0.33
2009 Trygstad TM, Pang Y, Forsyth CJ. Versatile synthesis of the C3-C14 domain of 7-deoxyokadaic acid. The Journal of Organic Chemistry. 74: 910-3. PMID 19072579 DOI: 10.1021/Jo8017457  0.621
2008 Forsyth CJ, Wang C. Synthesis and stereochemistry of the terminal spiroketal domain of the phosphatase inhibitor dinophysistoxin-2. Bioorganic & Medicinal Chemistry Letters. 18: 3043-6. PMID 18226903 DOI: 10.1016/J.Bmcl.2008.01.002  0.608
2008 Burns AC, Forsyth CJ. Intramolecular Diels-Alder/Tsuji allylation assembly of the functionalized trans-decalin of salvinorin A. Organic Letters. 10: 97-100. PMID 18062692 DOI: 10.1021/Ol7024058  0.365
2007 Li Y, Zhou F, Forsyth CJ. Gold(I)-catalyzed bis-spiroketalization: synthesis of the trioxadispiroketal-containing A-D rings of azaspiracid. Angewandte Chemie (International Ed. in English). 46: 279-82. PMID 17143913 DOI: 10.1002/ANIE.200601963  0.544
2007 Ying L, Forsyth CJ. Synthesis of a 16-triazole phorboxazole a analog via intramolecular triazole formation Heterocycles. 73: 841-855. DOI: 10.3987/COM-07-S(U)63  0.699
2006 Forsyth CJ, Xu J, Nguyen ST, Samdal IA, Briggs LR, Rundberget T, Sandvik M, Miles CO. Antibodies with broad specificity to azaspiracids by use of synthetic haptens. Journal of the American Chemical Society. 128: 15114-6. PMID 17117862 DOI: 10.1021/ja066971h  0.767
2006 Wang B, Forsyth CJ. Stereoselective synthesis of the phorboxazole A macrolide by ring-closing metathesis. Organic Letters. 8: 5223-6. PMID 17078683 DOI: 10.1021/ol0619922  0.465
2006 Wang C, Forsyth CJ. Synthesis of the spirastrellolide A trioxadispiroketal. Organic Letters. 8: 2997-3000. PMID 16805536 DOI: 10.1021/ol0609457  0.504
2006 Forsyth CJ, Ying L, Chen J, La Clair JJ. Phorboxazole analogues induce association of cdk4 with extranuclear cytokeratin intermediate filaments. Journal of the American Chemical Society. 128: 3858-9. PMID 16551063 DOI: 10.1021/ja057087e  0.633
2006 Chen J, Ying L, Hansen TM, Engler MM, Lee CS, La Clair JJ, Forsyth CJ. Design and total synthesis of a fluorescent phorboxazole A analog for cellular studies. Bioorganic & Medicinal Chemistry Letters. 16: 901-4. PMID 16300946 DOI: 10.1016/j.bmcl.2005.10.109  0.666
2006 Nguyen S, Xu J, Forsyth CJ. Facile biomimetic syntheses of the azaspiracid spiroaminal Tetrahedron. 62: 5338-5346. DOI: 10.1016/j.tet.2006.01.112  0.749
2004 Chen J, Forsyth CJ. Total synthesis of the marine cyanobacterial cyclodepsipeptide apratoxin A. Proceedings of the National Academy of Sciences of the United States of America. 101: 12067-72. PMID 15231999 DOI: 10.1073/pnas.0402752101  0.335
2001 Dounay AB, Urbanek RA, Frydrychowski VA, Forsyth CJ. Expedient access to the okadaic acid architecture: a novel synthesis of the C1-C27 domain. The Journal of Organic Chemistry. 66: 925-38. PMID 11430115 DOI: 10.1021/jo001433n  0.357
2001 Dounay AB, Forsyth CJ. Synthetic studies toward the C5-C20 domain of the azaspiracids. Organic Letters. 3: 975-8. PMID 11277773 DOI: 10.5555/ol015570y  0.42
2001 Hao J, Aiguade J, Forsyth CJ. Remarkably chemoselective indium-mediated coupling en route to the C21-C40 acyclic portion of the azaspiracids Tetrahedron Letters. 42: 821-824. DOI: 10.1016/S0040-4039(00)02157-2  0.309
2001 Forsyth CJ, Hao J, Aiguade J. Synthesis of the (+)-C26-C40 Domain of the Azaspiracids by a Novel Double Intramolecular Hetero-Michael Addition Strategy Angewandte Chemie. 113: 3775-3779. DOI: 10.1002/1521-3757(20011001)113:19<3775::AID-ANGE3775>3.0.CO;2-#  0.356
1999 Dounay AB, Forsyth CJ. Abbreviated synthesis of the C3-C14 (substituted 1,7-dioxaspiro[5.5]undec-3-ene) system of okadaic acid. Organic Letters. 1: 451-3. PMID 10822585  0.333
1999 González IC, Forsyth CJ. Novel synthesis of the C1-C15 polyether domain of the thyrsiferol and venustatriol natural products. Organic Letters. 1: 319-22. PMID 10822569  0.356
1998 Urbanek RA, Sabes SF, Forsyth CJ. Efficient synthesis of okadaic acid. 1. Convergent assembly of the C15- C38 domain Journal of the American Chemical Society. 120: 2523-2533. DOI: 10.1021/ja973287h  0.325
1998 Sabes SF, Urbanek RA, Forsyth CJ. Efficient synthesis of okadaic acid. 2. Synthesis of the C1-C14 domain and completion of the total synthesis Journal of the American Chemical Society. 120: 2534-2542. DOI: 10.1021/ja973286p  0.361
1998 Ahmed F, Forsyth CJ. Convergent synthesis of the C31-C46 domain of the phorboxazole natural products Tetrahedron Letters. 39: 183-186. DOI: 10.1016/S0040-4039(97)10519-6  0.332
1997 Cink RD, Forsyth CJ. Stereoselective synthesis of the C3-C17 bis-oxane domain of phorboxazole A Journal of Organic Chemistry. 62: 5672-5673. DOI: 10.1021/jo9708755  0.345
1996 Lee CS, Forsyth CJ. Synthesis of the central C18-C30 core of the phorboxazole natural products Tetrahedron Letters. 37: 6449-6452. DOI: 10.1016/0040-4039(96)01435-9  0.333
1995 Huang H, Forsyth CJ. Anti selective spirocarbomercuration: Synthesis and stereochemistry of the spirobicyclic sesquiterpenes spirojatamol and erythrodiene Journal of Organic Chemistry. 60: 2773-2779. DOI: 10.1021/Jo00114A027  0.319
1992 Buszek KR, Fang FG, Forsyth CJ, Jung SH, Kishi Y, Scola PM, Yoon SK. Synthetic Studies Towards Halichondrins: Synthesis of the Left Half of Halichondrins Tetrahedron Letters. 33: 1553-1556. DOI: 10.1016/S0040-4039(00)91672-1  0.435
1992 Aicher TD, Buszek KR, Fang FG, Forsyth CJ, Jung SH, Kishi Y, Scola PM. Synthetic Studies towards Halichondrins: Synthesis of the C.27-C.38 Segment Tetrahedron Letters. 33: 1549-1552. DOI: 10.1016/S0040-4039(00)91671-X  0.506
1990 Forsyth CJ, Clardy J. Total syntheses of (+)- and (-)-didemnenones A and B. Antiselectivity in the intramolecular carbomercuration reaction Journal of the American Chemical Society. 112: 3497-3505. DOI: 10.1021/Ja00165A038  0.387
1988 Lindquist N, Fenical W, Sesin DF, Ireland CM, Van Duyne GD, Forsyth CJ, Clardy J. Isolation and structure determination of the didemnenones, novel cytotoxic metabolites from tunicates Journal of the American Chemical Society. 110: 1308-1309.  0.596
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