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Year Citation  Score
2015 Diepold J, Ruhdorfer A, Dannhauer T, Wirth W, Steidle E, Eckstein F. Sex-differences of the healthy infra-patellar (Hoffa) fat pad in relation to intermuscular and subcutaneous fat content - Data from the Osteoarthritis Initiative. Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. 200: 30-6. PMID 25723518 DOI: 10.1016/j.aanat.2014.12.004  0.08
2014 Eckstein F. Phosphorothioates, essential components of therapeutic oligonucleotides. Nucleic Acid Therapeutics. 24: 374-87. PMID 25353652 DOI: 10.1089/nat.2014.0506  1
2010 Begemann M, Grube S, Papiol S, Malzahn D, Krampe H, Ribbe K, Friedrichs H, Radyushkin KA, El-Kordi A, Benseler F, Hannke K, Sperling S, Schwerdtfeger D, Thanhäuser I, Gerchen MF, ... ... Eckstein F, et al. Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms. Archives of General Psychiatry. 67: 879-88. PMID 20819981 DOI: 10.1001/archgenpsychiatry.2010.107  1
2010 Eckstein F. Introduction to the themed issue in honour of Professor Wojciech J. Stec New Journal of Chemistry. 34: 783. DOI: 10.1039/c001797n  1
2010 Eckstein F. Foreword The Chemical Biology of Nucleic Acids. vii-viii. DOI: 10.1002/9780470664001  1
2009 Eckstein F. New developments of the various classes of oligonucleotides. Preface. Annals of the New York Academy of Sciences. 1175: 1-2. PMID 19796071 DOI: 10.1111/j.1749-6632.2009.05016.x  1
2007 Eckstein F. Phosphorothioation of DNA in bacteria. Nature Chemical Biology. 3: 689-90. PMID 17948013 DOI: 10.1038/nchembio1107-689  1
2007 Eckstein F. The versatility of oligonucleotides as potential therapeutics. Expert Opinion On Biological Therapy. 7: 1021-34. PMID 17665991 DOI: 10.1517/14712598.7.7.1021  1
2005 Eckstein F. Small non-coding RNAs as magic bullets. Trends in Biochemical Sciences. 30: 445-52. PMID 15996867 DOI: 10.1016/j.tibs.2005.06.008  1
2003 Rossi J, Eckstein F. RNAi Impacts the World of Antisense Oligonucleotides. 13: 279-280. DOI: 10.1089/154545703322616952  1
2003 Sczakiel G, Soreq H, Greiner B, Gekeler V, Lemaitre M, Park WS, Miyano-Kurosaki N, Hayafune M, Takaku H, Borkhardt A, Sproat BS, Nielsen PE, Hartmann G, Endres S, Heckelsmiller K, ... ... Eckstein F, et al. Workshop: Therapeutic oligonucleotides in drug development Arzneimittel-Forschung/Drug Research. 53: 449-466.  1
2002 Eckstein F. Developments in RNA chemistry, a personal view Biochimie. 84: 841-848. PMID 12458076 DOI: 10.1016/S0300-9084(02)01459-1  1
2002 Persson T, Hartmann RK, Eckstein F. Selection of hammerhead ribozyme variants with low Mg2+ requirement: importance of stem-loop II. Chembiochem : a European Journal of Chemical Biology. 3: 1066-71. PMID 12404631 DOI: 10.1002/1439-7633(20021104)3:11<1066::AID-CBIC1066>3.0.CO;2-G  1
2002 Eckstein F. Side-effects and phosphorothioates. Nature Biotechnology. 20: 549. PMID 12042851 DOI: 10.1038/nbt0602-549a  1
2001 Eckstein F, Kore AR, Nakamaye KL. In vitro selection of hammerhead ribozyme sequence variants Chembiochem. 2: 629-635. PMID 11828499  1
2001 Lilley DMJ, Gait M, Eckstein F. Who will fill the gap by making nucleic synthesizers now? [1] Nature. 411: 15. PMID 11333947  1
2001 Galyam N, Grisaru D, Grifman M, Melamed-Book N, Eckstein F, Seidman S, Eldor A, Soreq H. Complex host cell responses to antisense suppression of ACHE gene expression. Antisense & Nucleic Acid Drug Development. 11: 51-7. PMID 11258621 DOI: 10.1089/108729001750072128  1
2000 Menger M, Eckstein F, Porschke D. Multiple conformational states of the hammerhead ribozyme, broad time range of relaxation and topology of dynamics Nucleic Acids Research. 28: 4428-4434. PMID 11071929  1
2000 Bramlage B, Luzi E, Eckstein F. HIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: Site selection and inhibition in cell culture Nucleic Acids Research. 28: 4059-4067. PMID 11058100  1
2000 Kore AR, Carola C, Eckstein F. Attempts to obtain more efficient GAC-cleaving hammerhead ribozymes by in vitro selection Bioorganic and Medicinal Chemistry. 8: 1767-1771. PMID 10976525 DOI: 10.1016/S0968-0896(00)00103-6  1
2000 Kore AR, Vaish NK, Morris JA, Eckstein F. In vitro evolution of the hammerhead ribozyme to a purine-specific ribozyme using mutagenic PCR with two nucleotide analogues. Journal of Molecular Biology. 301: 1113-21. PMID 10966809 DOI: 10.1006/jmbi.2000.4020  1
2000 Mariani L, Citti L, Nevischi S, Eckstein F, Rainaldi G. Ribozyme and free alkylated base: A dual approach for sensitizing Mex+ cells to the alkylating antineoplastic drug Cancer Gene Therapy. 7: 905-909. PMID 10880022  1
2000 Claus L, Vörtler S, Eckstein F. Phosphorothioate modification of RNA for stereochemical and interference analyses Methods in Enzymology. 317: 74-91. PMID 10829273  1
2000 Eckstein F. Phosphorothioate oligodeoxynucleotides: What is their origin and what is unique about them? Antisense and Nucleic Acid Drug Development. 10: 117-121. PMID 10805163  1
2000 Müller MO, Meylan-Bettex M, Eckstein F, Martinoia E, Siegenthaler PA, Bovet L. Lipid phosphorylation in chloroplast envelopes: Evidence for galactolipid CTP-dependent kinase activities Journal of Biological Chemistry. 275: 19475-19481. PMID 10777505 DOI: 10.1074/jbc.M002575200  1
2000 Menger M, Eckstein F, Porschke D. Dynamics of the RNA hairpin GNRA tetraloop Biochemistry. 39: 4500-4507. PMID 10757999 DOI: 10.1021/bi992297n  1
1999 Eckstein F, Bramlage B. The hammerhead ribozyme Biopolymers. 52: 147-154. PMID 11169382 DOI: 10.1002/1097-0282(1999)52:3<147::AID-BIP40>3.0.CO;2-I  1
1999 Rajani C, Kincaid JR, Petering DH. The presence of two modes of binding to calf thymus DNA by metal-free bleomycin: a low frequency Raman study. Biopolymers. 52: 129-46. PMID 11169381 DOI: 10.1002/1097-0282(1999)52:3<129::AID-BIP30>3.0.CO;2-N  1
1999 Seidman S, Eckstein F, Grifman M, Soreq H. Antisense technologies have a future fighting neurodegenerative diseases. Antisense & Nucleic Acid Drug Development. 9: 333-40. PMID 10463077  1
1999 Kore AR, Eckstein F. Hammerhead ribozyme mechanism: A ribonucleotide 5' to the substrate cleavage site is not essential Biochemistry. 38: 10915-10918. PMID 10460146 DOI: 10.1021/bi991332n  1
1999 Bramlage B, Alefelder S, Marschall P, Eckstein F. Inhibition of luciferase expression by synthetic hammerhead ribozymes and their cellular uptake Nucleic Acids Research. 27: 3159-3167. PMID 10454613 DOI: 10.1093/nar/27.15.3159  1
1999 Carola C, Eckstein F. Nucleic acid enzymes Current Opinion in Chemical Biology. 3: 274-283. PMID 10359709 DOI: 10.1016/S1367-5931(99)80043-X  1
1999 Citti L, Eckstein F, Capecchi B, Mariani L, Nevischi S, Poggi A, Rainaldi G. Transient transfection of a synthetic hammerhead ribozyme targeted against human MGMT gene to cells in culture potentiates the genotoxicity of the alkylation damage induced by mitozolomide Antisense and Nucleic Acid Drug Development. 9: 125-133. PMID 10355819  1
1999 Grisaru D, Lev-Lehman E, Shapira M, Chaikin E, Lessing JB, Eldor A, Eckstein F, Soreq H. Human osteogenesis involves differentiation-dependent increases in the morphogenically active 3' alternative splicing variant of acetylcholinesterase. Molecular and Cellular Biology. 19: 788-95. PMID 9858601  1
1998 Vaish NK, Kore AR, Eckstein F. Recent developments in the hammerhead ribozyme field Nucleic Acids Research. 26: 5237-5242. PMID 9826743  1
1998 Vörtler CS, Fedorova O, Persson T, Kutzke U, Eckstein F. Determination of 2'-hydroxyl and phosphate groups important for aminoacylation of Escherichia coli tRNA(Asp): A nucleotide analogue interference study Rna. 4: 1444-1454. PMID 9814764 DOI: 10.1017/S1355838298980967  1
1998 Bramlage B, Luzi E, Eckstein F. Designing ribozymes for the inhibition of gene expression Trends in Biotechnology. 16: 434-438. PMID 9807841 DOI: 10.1016/S0167-7799(98)01236-0  1
1998 Alefelder S, Patel BK, Eckstein F. Incorporation of terminal phosphorothioates into oligonucleotides Nucleic Acids Research. 26: 4983-4988. PMID 9776763 DOI: 10.1093/nar/26.21.4983  1
1998 Venna S, Eckstein F. Modified oligonucleotides: Synthesis and strategy for users Annual Review of Biochemistry. 67: 99-134. PMID 9759484 DOI: 10.1146/annurev.biochem.67.1.99  1
1998 Kore AR, Vaish NK, Kutzke U, Eckstein F. Sequence specificity of the hammerhead ribozyme revisited; The NHH rule Nucleic Acids Research. 26: 4116-4120. PMID 9722629 DOI: 10.1093/nar/26.18.4116  1
1998 Vaish NK, Heaton PA, Fedorova O, Eckstein F. In vitro selection of a purine nucleotide-specific hammerhead-like ribozyme Proceedings of the National Academy of Sciences of the United States of America. 95: 2158-2162. PMID 9482855 DOI: 10.1073/pnas.95.5.2158  1
1998 Eckstein F. Searching for the ideal partner Nature Biotechnology. 16: 24. PMID 9447587  1
1997 Verma S, Vaish NK, Eckstein F. Structure-function studies of the hammerhead ribozyme Current Opinion in Chemical Biology. 1: 532-536. PMID 9667883  1
1997 Earnshaw DJ, Masquida B, Müller S, Sigurdsson ST, Eckstein F, Westhof E, Gait MJ. Inter-domain cross-linking and molecular modelling of the hairpin ribozyme. Journal of Molecular Biology. 274: 197-212. PMID 9398527 DOI: 10.1006/jmbi.1997.1405  1
1997 Eckstein F. Exogenous application of ribozymes for inhibiting gene expression Ciba Foundation Symposia. 207-217. PMID 9383578  1
1997 Luzi E, Eckstein F, Barsacchi G. The newt ribozyme is part of a riboprotein complex. Proceedings of the National Academy of Sciences of the United States of America. 94: 9711-6. PMID 9275189 DOI: 10.1073/pnas.94.18.9711  1
1997 Marusic L, Luzi E, Barsacchi G, Eckstein F. Intermolecular cleavage by the newt ribozyme. European Journal of Biochemistry / Febs. 247: 396-401. PMID 9249052  1
1997 Huang Y, Eckstein F, Padilla R, Sousa R. Mechanism of ribose 2'-group discrimination by an RNA polymerase Biochemistry. 36: 8231-8242. PMID 9204868 DOI: 10.1021/bi962674l  1
1997 Vaish NK, Heaton PA, Eckstein F. Isolation of hammerhead ribozymes with altered core sequences by in vitro selection Biochemistry. 36: 6495-6501. PMID 9174367 DOI: 10.1021/bi963134r  1
1997 Birikh KR, Heaton PA, Eckstein F. The structure, function and application of the hammerhead ribozyme European Journal of Biochemistry. 245: 1-16. PMID 9128718  1
1997 Birikh KR, Berlin YA, Soreq H, Eckstein F. Probing accessible sites for ribozymes on human acetylcholinesterase RNA. Rna (New York, N.Y.). 3: 429-37. PMID 9085849  1
1997 Hormes R, Homann M, Oelze I, Marschall P, Tabler M, Eckstein F, Sczakiel G. The subcellular localization and length of hammerhead ribozymes determine efficacy in human cells Nucleic Acids Research. 25: 769-775. PMID 9016627 DOI: 10.1093/nar/25.4.769  1
1997 Patel BK, Eckstein F. 5'-Deoxy-5'-thioribonucleoside-5'-triphosphates Tetrahedron Letters. 38: 1021-1024. DOI: 10.1016/S0040-4039(97)00084-1  1
1997 Patel BK, Thomson JB, Jiménez V, Eckart K, Eckstein F. Properties of some diuridine phosphate analogues Nucleosides and Nucleotides. 16: 1443-1446.  1
1997 Persson T, Vortler CS, Fedorova O, Eckstein F. Incorporation of 2'-modified nucleotides into tRNA to test importance for charging Nucleosides and Nucleotides. 16: 797-800.  1
1996 Thomson JB, Patel BK, Jiménez V, Eckart K, Eckstein F. Synthesis and Properties of Diuridine Phosphate Analogues Containing Thio and Amino Modifications. The Journal of Organic Chemistry. 61: 6273-6281. PMID 11667467 DOI: 10.1021/jo960795l  1
1996 Sigurdsson ST, Seeger B, Kutzke U, Eckstein F. A Mild and Simple Method for the Preparation of Isocyanates from Aliphatic Amines Using Trichloromethyl Chloroformate. Synthesis of an Isocyanate Containing an Activated Disulfide. The Journal of Organic Chemistry. 61: 3883-3884. PMID 11667245  1
1996 Thomson JB, Sigurdsson ST, Zeuch A, Eckstein F. In vitro selection of hammerhead ribozymes containing a bulged nucleotide in stem II. Nucleic Acids Research. 24: 4401-6. PMID 8948630 DOI: 10.1093/nar/24.22.4401  1
1996 Menger M, Tuschl T, Eckstein F, Porschke D. Mg(2+)-dependent conformational changes in the hammerhead ribozyme. Biochemistry. 35: 14710-6. PMID 8942631 DOI: 10.1021/bi960440w  1
1996 Eckstein F, Krieg AM, Stein CA, Agrawal S, Beaucage S, Cook PD, Crooke S, Gait MJ, Gewirtz A, Hélène C, Miller P, Narayanan R, Nicolin A, Nielsen P, Ohtsuka E, et al. On the quality control of antisense oligonucleotides. Antisense & Nucleic Acid Drug Development. 6: 149. PMID 8915496  1
1996 Sigurdsson ST, Eckstein F. Isolation of oligoribonucleotides containing intramolecular cross-links. Analytical Biochemistry. 235: 241-2. PMID 8833336 DOI: 10.1006/abio.1996.0120  1
1996 Snorri TS, Eckstein F. Site specific labelling of sugar residues in oligoribonucleotides: Reactions of aliphatic isocyanates with 2' amino groups Nucleic Acids Research. 24: 3129-3133. PMID 8774891  1
1996 Heaton PA, Eckstein F. Diastereomeric specificity of 2′,3′-cyclic nucleotide 3′-phosphodiesterase Nucleic Acids Research. 24: 850-853. PMID 8600451 DOI: 10.1093/nar/24.5.850  1
1996 Sigurdsson ST, Seeger B, Kutzke U, Eckstein F. A mild and simple method for the preparation of isocyanates from aliphatic amines using trichloromethyl chloroformate. synthesis of an isocyanate containing an activated disulfide Journal of Organic Chemistry. 61: 3883-3884.  1
1995 Behravan G, Sen S, Rova U, Thelander L, Eckstein F, Gräslund A. Formation of a free radical of the sulfenylimine type in the mouse ribonucleotide reductase reaction with 2′-azido-2′-deoxycytidine 5′-diphosphate Bba - Gene Structure and Expression. 1264: 323-329. PMID 8547320 DOI: 10.1016/0167-4781(95)00168-9  1
1995 Sigurdsson ST, Eckstein F. Structure-function relationships of hammerhead ribozymes: from understanding to applications. Trends in Biotechnology. 13: 286-9. PMID 7662303 DOI: 10.1016/S0167-7799(00)88966-0  1
1995 Heidenreich O, Kang SH, Brown DA, Xu X, Swiderski P, Rossi JJ, Eckstein F, Nerenberg M. Ribozyme-mediated RNA degradation in nuclei suspension Nucleic Acids Research. 23: 2223-2228. PMID 7610051  1
1995 Tuschl T, Thomson JB, Eckstein F. RNA cleavage by small catalytic RNAs. Current Opinion in Structural Biology. 5: 296-302. PMID 7583627 DOI: 10.1016/0959-440X(95)80090-5  1
1995 Sigurdsson ST, Tuschl T, Eckstein F. Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme. Rna (New York, N.Y.). 1: 575-83. PMID 7489517  1
1994 Heidenreich O, Benseler F, Fahrenholz A, Eckstein F. High activity and stability of hammerhead ribozymes containing 2'-modified pyrimidine nucleosides and phosphorothioates Journal of Biological Chemistry. 269: 2131-2138. PMID 8294467  1
1994 Aurup H, Tuschl T, Benseler F, Ludwig J, Eckstein F. Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity. Nucleic Acids Research. 22: 20-4. PMID 8127651 DOI: 10.1093/nar/22.1.20  1
1994 Nakamaye KL, Eckstein F. AUA-cleaving hammerhead ribozymes: Attempted selection for improved cleavage Biochemistry. 33: 1271-1277. PMID 8110761  1
1994 Soreq H, Patinkin D, Lev-Lehman E, Grifman M, Ginzberg D, Eckstein F, Zakut H. Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo. Proceedings of the National Academy of Sciences of the United States of America. 91: 7907-11. PMID 8058733 DOI: 10.1073/pnas.91.17.7907  1
1994 Tuschl T, Gohlke C, Jovin TM, Westhof E, Eckstein F. A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements. Science (New York, N.Y.). 266: 785-9. PMID 7973630  1
1994 Eliasson R, Pontis E, Eckstein F, Reichard P. Interactions of 2'-modified azido- and haloanalogs of deoxycytidine 5'- triphosphate with the anaerobic ribonucleotide reductase of Escherichia coli Journal of Biological Chemistry. 269: 26116-26120. PMID 7929323  1
1994 Ng MM, Benseler F, Tuschl T, Eckstein F. Isoguanosine substitution of conserved adenosines in the hammerhead ribozyme. Biochemistry. 33: 12119-26. PMID 7918433 DOI: 10.1021/bi00206a015  1
1994 Ehrlich G, Patinkin D, Ginzberg D, Zakut H, Eckstein F, Soreq H. Use of partially phosphorothioated "antisense" oligodeoxynucleotides for sequence-dependent modulation of hematopoiesis in culture. Antisense Research and Development. 4: 173-83. PMID 7849488  1
1994 Aurup H, Siebert A, Benseler F, Williams D, Eckstein F. Translation of 2'-modified mRNA in vitro and in vivo. Nucleic Acids Research. 22: 4963-8. PMID 7800487 DOI: 10.1093/nar/22.23.4963  1
1994 Marschall P, Thomson JB, Eckstein F. Inhibition of gene expression with ribozymes Cellular and Molecular Neurobiology. 14: 523-538. PMID 7621511 DOI: 10.1007/BF02088835  1
1994 Patinkin D, Lev-Lehman E, Zakut H, Eckstein F, Soreq H. Antisense inhibition of butyrylcholinesterase gene expression predicts adverse hematopoietic consequences to cholinesterase inhibitors. Cellular and Molecular Neurobiology. 14: 459-73. PMID 7621507 DOI: 10.1007/BF02088831  1
1994 Lev-Lehman E, Ginzberg D, Hornreich G, Ehrlich G, Meshorer A, Eckstein F, Soreq H, Zakut H. Antisense inhibition of acetylcholinesterase gene expression causes transient hematopoietic alterations in vivo. Gene Therapy. 1: 127-35. PMID 7584068  1
1994 Aurup H, Tuschl T, Benseler F, Ludwig J, Eckstein F. Oligonucleotide duplexes containing 2′-amino-2′deoxycytidines: Thermal stability and chemical reactivity Nucleic Acids Research. 22: 701. DOI: 10.1093/nar/22.4.701  1
1993 Olsen DB, Wunderlich G, Uy A, Eckstein F. Direct sequencing of polymerase chain reaction products Methods in Enzymology. 218: 79-92. PMID 8389972  1
1993 Olsen DB, Sayers JR, Eckstein F. Site-directed mutagenesis of single-stranded and double-stranded DNA by phosphorothioate approach. Methods in Enzymology. 217: 189-217. PMID 8386289  1
1993 Bebenek K, Thomas DC, Roberts JD, Eckstein F, Kunkel TA. Effects of 3′-azido-3′-deoxythymidine metabolites on simian virus 40 origin-dependent replication and heteroduplex repair in HeLa cell extracts Molecular Pharmacology. 43: 57-63. PMID 8380884  1
1993 Ceska TA, Sayers JR, Eckstein F, Suck D. Preliminary crystallographic studies on the D15 5' to 3' exonuclease from phage T5. Journal of Molecular Biology. 233: 179-82. PMID 8377188 DOI: 10.1006/jmbi.1993.1496  1
1993 Tuschl T, Eckstein F. Hammerhead ribozymes: importance of stem-loop II for activity. Proceedings of the National Academy of Sciences of the United States of America. 90: 6991-4. PMID 8346207  1
1993 Eckstein F, Aurup H, Benseler F, Heidenreich O, Marschall P, Ng M, Thomson J, Tuschl T. Design of hammerhead ribozymes for the inhibition of gene expression ex vivo by exogenous application. Nucleic Acids Symposium Series. 115. PMID 8247729  1
1993 Tuschl T, Ng MM, Pieken W, Benseler F, Eckstein F. Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity. Biochemistry. 32: 11658-68. PMID 8218233 DOI: 10.1021/bi00094a023  1
1993 Heidenreich O, Pieken W, Eckstein F. Chemically modified RNA: Approaches and applications Faseb Journal. 7: 90-96. PMID 7678566  1
1993 Thomson JB, Tuschl T, Eckstein F. Activity of hammerhead ribozymes containing non-nucleotidic linkers. Nucleic Acids Research. 21: 5600-3. PMID 7506829  1
1992 Williams DM, Pieken WA, Eckstein F. Function of specific 2′-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2′ modifications Proceedings of the National Academy of Sciences of the United States of America. 89: 918-921. PMID 1736306  1
1992 Lapidot-Lifson Y, Patinkin D, Prody CA, Ehrlich G, Seidman S, Ben-Aziz R, Benseler F, Eckstein F, Zakut H, Soreq H. Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 89: 579-83. PMID 1731328  1
1992 Heidenreich O, Eckstein F. Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1 Journal of Biological Chemistry. 267: 1904-1909. PMID 1730726  1
1992 Rudinger J, Puglisi JD, Pütz J, Schatz D, Eckstein F, Florentz C, Giegé R. Determinant nucleotides of yeast tRNA(Asp) interact directly with aspartyl-tRNA synthetase. Proceedings of the National Academy of Sciences of the United States of America. 89: 5882-6. PMID 1631068  1
1992 Hertel KJ, Pardi A, Uhlenbeck OC, Koizumi M, Ohtsuka E, Uesugi S, Cedergren R, Eckstein F, Gerlach WL, Hodgson R. Numbering system for the hammerhead. Nucleic Acids Research. 20: 3252. PMID 1620624  1
1992 Sayers JR, Krekel C, Eckstein F. Rapid high-efficiency site-directed mutagenesis by the phosphorothioate approach. Biotechniques. 13: 592-6. PMID 1476729  1
1992 Aurup H, Williams DM, Eckstein F. 2′-Fluoro- and 2′-amino-2′-deoxynucleoside 5′-triphosphates as substrates for T7 RNA polymerase Biochemistry. 31: 9636-9641. PMID 1390741 DOI: 10.1021/bi00155a016  1
1992 Benseler F, Williams DM, Eckstein F. Synthesis of suitably-protected phosphoramidites of 2‘-fluoro-2’-deoxyguanosine and ‘-amino-2’-deoxyguanosine for incorporation into oligoribonucleotides Nucleosides and Nucleotides. 11: 1333-1351. DOI: 10.1080/07328319208021177  1
1991 Ueda T, Tohda H, Chikazumi N, Eckstein F, Watanabe K. Phosphorothioate-containing RNAs show mRNA activity in the prokaryotic translation systems in vitro. Nucleic Acids Research. 19: 547-52. PMID 2011526 DOI: 10.1093/nar/19.3.547  1
1990 Garcia GA, Leatherbarrow RJ, Eckstein F, Fersht AR. Metal ion dependence of phosphorothioate ATP analogues in the Bacillus stearothermophilus tyrosyl-tRNA synthetase reaction Biochemistry. 29: 1643-1648. PMID 2334722 DOI: 10.1021/bi00458a041  1
1990 Patinkin D, Seidman S, Eckstein F, Benseler F, Zakut H, Soreq H. Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro. Molecular and Cellular Biology. 10: 6046-50. PMID 2233731 DOI: 10.1128/MCB.10.11.6046  0.32
1990 van Tol H, Buzayan JM, Feldstein PA, Eckstein F, Bruening G. Two autolytic processing reactions of a satellite RNA proceed with inversion of configuration Nucleic Acids Research. 18: 1971-1975. PMID 1692411 DOI: 10.1093/nar/18.8.1971  1
1988 Buzayan JM, Feldstein PA, Bruening G, Eckstein F. RNA mediated formation of a phosphorothioate diester bond Biochemical and Biophysical Research Communications. 156: 340-347. PMID 3178838 DOI: 10.1016/S0006-291X(88)80846-5  1
1988 Spitzer S, Eckstein F. Inhibition of deoxyribonucleases by phosphorothioate groups in oligodeoxyribonucleotides Nucleic Acids Research. 16: 11691-11704. PMID 2850541 DOI: 10.1093/nar/16.24.11691  1
1987 Fernandez JM, Lindau M, Eckstein F. Intracellular stimulation of mast cells with guanine nucleotides mimic antigenic stimulation. Febs Letters. 216: 89-93. PMID 3108035 DOI: 10.1016/0014-5793(87)80762-7  1
1986 Yamanaka G, Eckstein F, Stryer L. Interaction of retinal transducin with guanosine triphosphate analogues: specificity of the gamma-phosphate binding region. Biochemistry. 25: 6149-53. PMID 3466646 DOI: 10.1021/bi00368a048  1
1985 Yamanaka G, Eckstein F, Stryer L. Stereochemistry of the guanyl nucleotide binding site of transducin probed by phosphorothioate analogues of GTP and GDP. Biochemistry. 24: 8094-101. PMID 3004574 DOI: 10.1021/bi00348a039  1
1985 Zimmerman AL, Yamanaka G, Eckstein F, Baylor DA, Stryer L. Interaction of hydrolysis-resistant analogs of cyclic GMP with the phosphodiesterase and light-sensitive channel of retinal rod outer segments. Proceedings of the National Academy of Sciences of the United States of America. 82: 8813-7. PMID 2417228 DOI: 10.1073/pnas.82.24.8813  1
1984 Connolly BA, Eckstein F. Assignment of resonances in the 31P NMR spectrum of d(GGAATTCC) by regiospecific labeling with oxygen-17 Biochemistry. 23: 5523-5527. PMID 6509032 DOI: 10.1021/bi00318a022  1
1984 Connolly BA, Eckstein F, Grotjahn L. Direct mass spectroscopic method for determination of oxygen isotope position in adenosine 5′-O-(1-thiotriphosphate). determination of the stereochemical course of the yeast phenylalanyl-trna synthetase reaction Biochemistry. 23: 2026-2031. PMID 6372864 DOI: 10.1021/bi00304a022  1
1984 Potter BV, Eckstein F. Cleavage of phosphorothioate-substituted DNA by restriction endonucleases. The Journal of Biological Chemistry. 259: 14243-8. PMID 6094546  1
1984 Connolly BA, Potter BVL, Eckstein F, Pingoud A, Grotjahn L. Synthesis and characterization of an octanucleotide containing the EcoRI recognition sequence with a phosphorothioate group at the cleavage site Biochemistry. 23: 3443-3453. PMID 6087894  1
1983 McIntosh LP, Grieger I, Eckstein F, Zarling DA, Van de Sande JH, Jovin TM. Left-handed helical conformation of poly[d(A-m5C) · d(G-T)] Nature. 304: 83-86. PMID 6866095 DOI: 10.1038/304083a0  1
1983 Potter BV, Eckstein F, Uznański B. A stereospecifically 18O-labelled deoxydinucleoside phosphate block for incorporation into an oligonucleotide. Nucleic Acids Research. 11: 7087-103. PMID 6634410 DOI: 10.1093/nar/11.20.7087  1
1983 Jovin TM, McIntosh LP, Arndt-Jovin DJ, Zarling DA, Robert-Nicoud M, Van De Sande JH, Jorgenson KF, Eckstein F. Left-handed dna: From synthetic polymers to chromosomes Journal of Biomolecular Structure and Dynamics. 1: 21-57. PMID 6401113 DOI: 10.1080/07391102.1983.10507425  1
1983 Potter BVL, Connolly BA, Eckstein F. Synthesis and configurational analysis of a dinucleoside phosphate isotopically chiral at phosphorus. Stereochemical course of Penicillium citrum nuclease P1 reaction Biochemistry. 22: 1369-1377. PMID 6301546  1
1983 Potter BV, Romaniuk PJ, Eckstein F. Stereochemical course of DNA hydrolysis by nuclease S1 Journal of Biological Chemistry. 258: 1758-1760. PMID 6296110  1
1982 Connolly BA, Eckstein F. S-methylated nucleoside phosphorothioates as probes of enzyme metal·nucleotide binding sites Biochemistry. 21: 6158-6167. PMID 7150548 DOI: 10.1021/bi00267a021  1
1982 Jovin TM, van De Sande JH, Zarling DA, Arndt-Jovin DJ, Eckstein F, Füldner HH, Greider C, Grieger I, Hamori E, Kalisch B, McIntosh LP, Robert-Nicoud M. Generation of left-handed Z-DNA in solution and visualization in polytene chromosomes by immunofluorescence Cold Spring Harbor Symposia On Quantitative Biology. 47: 143-154. PMID 6345056 DOI: 10.1101/SQB.1983.047.01.019  1
1982 Eckstein F, Romaniuk PJ, Connolly BA. [13] Stereochemistry of enzymic phosphoryl and nucleotidyl transfer Methods in Enzymology. 87: 197-212. DOI: 10.1016/S0076-6879(82)87015-8  1
1981 Kunkel TA, Eckstein F, Mildvan AS, Koplitz RM, Loeb LA. Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis Proceedings of the National Academy of Sciences of the United States of America. 78: 6734-6738. PMID 6458818 DOI: 10.1073/pnas.78.11.6734  1
1974 Bagshaw CR, Eccleston JF, Eckstein F, Goody RS, Gutfreund H, Trentham DR. The magnesium ion-dependent adenosine triphosphatase of myosin. Two-step processes of adenosine triphosphate association and adenosine diphosphate dissociation. The Biochemical Journal. 141: 351-64. PMID 4281654 DOI: 10.1042/bj1410351  1
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