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Jason Micklefield, PhD - Publications

Affiliations: 
Manchester Institute of Biotechnology University of Manchester, Manchester, England, United Kingdom 
Area:
Nucleic Acid Redesign and Recognition, Biocatalysis and Enzyme Mechanism, Biosynthesis and Biosynthetic Engineering
Website:
http://www.manchester.ac.uk/research/Jason.micklefield/

87 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Dunstan MS, Robinson CJ, Jervis AJ, Yan C, Carbonell P, Hollywood KA, Currin A, Swainston N, Feuvre RL, Micklefield J, Faulon JL, Breitling R, Turner N, Takano E, Scrutton NS. Engineering towards production of gatekeeper (2)-flavanones: naringenin, pinocembrin, eriodictyol and homoeriodictyol. Synthetic Biology (Oxford, England). 5: ysaa012. PMID 33195815 DOI: 10.1093/synbio/ysaa012  0.36
2020 Robinson CJ, Carbonell P, Jervis AJ, Yan C, Hollywood KA, Dunstan MS, Currin A, Swainston N, Spiess R, Taylor S, Mulherin P, Parker S, Rowe W, Matthews NE, Malone KJ, ... ... Micklefield J, et al. Rapid prototyping of microbial production strains for the biomanufacture of potential materials monomers. Metabolic Engineering. PMID 32335188 DOI: 10.1016/j.ymben.2020.04.008  0.36
2018 Carbonell P, Jervis AJ, Robinson CJ, Yan C, Dunstan M, Swainston N, Vinaixa M, Hollywood KA, Currin A, Rattray NJW, Taylor S, Spiess R, Sung R, Williams AR, Fellows D, ... ... Micklefield J, et al. An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals. Communications Biology. 1: 66. PMID 30271948 DOI: 10.1038/s42003-018-0076-9  0.36
2016 Robinson CJ, Medina-Stacey D, Wu MC, Vincent HA, Micklefield J. Rewiring Riboswitches to Create New Genetic Circuits in Bacteria. Methods in Enzymology. 575: 319-48. PMID 27417935 DOI: 10.1016/bs.mie.2016.02.022  0.44
2016 Carbonell P, Currin A, Dunstan M, Fellows D, Jervis A, Rattray NJ, Robinson CJ, Swainston N, Vinaixa M, Williams A, Yan C, Barran P, Breitling R, Chen GG, Faulon JL, ... ... Micklefield J, et al. SYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals. Biochemical Society Transactions. 44: 675-7. PMID 27284023 DOI: 10.1042/BST20160009  0.36
2016 Latham J, Henry JM, Sharif HH, Menon BR, Shepherd SA, Greaney MF, Micklefield J. Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C-H activation. Nature Communications. 7: 11873. PMID 27283121 DOI: 10.1038/ncomms11873  0.44
2016 Zabala D, Cartwright JW, Roberts DM, Law BJ, Song L, Samborskyy M, Leadlay PF, Micklefield J, Challis GL. A flavin-dependent decarboxylase-dehydrogenase-monooxygenase assembles the warhead of α, β-epoxyketone proteasome inhibitors. Journal of the American Chemical Society. PMID 26999044 DOI: 10.1021/jacs.6b01619  0.44
2016 Struck AW, Bennett MR, Shepherd SA, Law BJ, Zhou Y, Wong LS, Micklefield J. An Enzyme Cascade for Selective Modification of Tyrosine Residues in Structurally Diverse Peptides and Proteins. Journal of the American Chemical Society. PMID 26867114 DOI: 10.1021/jacs.5b10928  0.44
2016 Law BJ, Bennett MR, Thompson ML, Levy C, Shepherd SA, Leys D, Micklefield J. Effects of Active-Site Modification and Quaternary Structure on the Regioselectivity of Catechol-O-Methyltransferase. Angewandte Chemie (International Ed. in English). PMID 26797714 DOI: 10.1002/anie.201508287  0.44
2016 Winn M, Fyans JK, Zhuo Y, Micklefield J. Recent advances in engineering nonribosomal peptide assembly lines Natural Product Reports. 33: 317-347. DOI: 10.1039/c5np00099h  0.44
2015 Morra R, Shankar J, Robinson CJ, Halliwell S, Butler L, Upton M, Hay S, Micklefield J, Dixon N. Dual transcriptional-translational cascade permits cellular level tuneable expression control. Nucleic Acids Research. PMID 26405200 DOI: 10.1093/nar/gkv912  0.36
2015 Wu MC, Lowe PT, Robinson CJ, Vincent HA, Dixon N, Leigh J, Micklefield J. Rational Re-engineering of a Transcriptional Silencing PreQ1 Riboswitch. Journal of the American Chemical Society. PMID 26106809 DOI: 10.1021/jacs.5b03405  0.44
2015 Wu MC, Styles MQ, Law BJ, Struck AW, Nunns L, Micklefield J. Engineered Biosynthesis of Enduracidin Lipoglycopeptide Antibiotics using the Ramoplanin Mannosyltransferase Ram29. Microbiology (Reading, England). PMID 25878261 DOI: 10.1099/mic.0.000095  0.44
2015 Lewin R, Goodall M, Thompson ML, Leigh J, Breuer M, Baldenius K, Micklefield J. Enzymatic enantioselective decarboxylative protonation of heteroaryl malonates. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 6557-63. PMID 25766433 DOI: 10.1002/chem.201406014  0.44
2015 Diez V, Loznik M, Taylor S, Winn M, Rattray NJ, Podmore H, Micklefield J, Goodacre R, Medema MH, Müller U, Bovenberg R, Janssen DB, Takano E. Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block. Acs Synthetic Biology. 4: 796-807. PMID 25713978 DOI: 10.1021/sb500368w  0.44
2015 Shepherd SA, Karthikeyan C, Latham J, Struck AW, Thompson ML, Menon BRK, Styles MQ, Levy C, Leys D, Micklefield J. Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes Chemical Science. 6: 3454-3460. DOI: 10.1039/c5sc00913h  0.44
2015 Law BJC, Struck AW, Bennett MR, Wilkinson B, Micklefield J. Site-specific bioalkylation of rapamycin by the RapM 16-O-methyltransferase Chemical Science. 6: 2885-2892. DOI: 10.1039/c5sc00164a  0.44
2014 Hosford J, Shepherd SA, Micklefield J, Wong LS. A high-throughput assay for arylamine halogenation based on a peroxidase-mediated quinone-amine coupling with applications in the screening of enzymatic halogenations. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 16759-63. PMID 25319801 DOI: 10.1002/chem.201403953  0.44
2014 Robinson CJ, Vincent HA, Wu MC, Lowe PT, Dunstan MS, Leys D, Micklefield J. Modular riboswitch toolsets for synthetic genetic control in diverse bacterial species. Journal of the American Chemical Society. 136: 10615-24. PMID 24971878 DOI: 10.1021/ja502873j  0.44
2014 Vincent HA, Robinson CJ, Wu MC, Dixon N, Micklefield J. Generation of orthogonally selective bacterial riboswitches by targeted mutagenesis and in vivo screening. Methods in Molecular Biology (Clifton, N.J.). 1111: 107-29. PMID 24549615 DOI: 10.1007/978-1-62703-755-6_8  0.44
2013 Gait MJ, Komiyama M, Seeman NC, Seitz O, Micklefield J, Liu DR. Nucleic acids: new life, new materials. Organic & Biomolecular Chemistry. 11: 2058-9. PMID 23429691 DOI: 10.1039/c3ob90017g  0.44
2012 Struck AW, Thompson ML, Wong LS, Micklefield J. S-adenosyl-methionine-dependent methyltransferases: highly versatile enzymes in biocatalysis, biosynthesis and other biotechnological applications. Chembiochem : a European Journal of Chemical Biology. 13: 2642-55. PMID 23180741 DOI: 10.1002/cbic.201200556  0.44
2012 Thirlway J, Lewis R, Nunns L, Al Nakeeb M, Styles M, Struck AW, Smith CP, Micklefield J. Introduction of a non-natural amino acid into a nonribosomal peptide antibiotic by modification of adenylation domain specificity. Angewandte Chemie (International Ed. in English). 51: 7181-4. PMID 22711659 DOI: 10.1002/anie.201202043  0.44
2012 Chen L, Cressina E, Dixon N, Erixon K, Agyei-Owusu K, Micklefield J, Smith AG, Abell C, Leeper FJ. Probing riboswitch-ligand interactions using thiamine pyrophosphate analogues. Organic & Biomolecular Chemistry. 10: 5924-31. PMID 22514012 DOI: 10.1039/c2ob07116a  0.44
2012 Wu MC, Law B, Wilkinson B, Micklefield J. Bioengineering natural product biosynthetic pathways for therapeutic applications. Current Opinion in Biotechnology. 23: 931-40. PMID 22487048 DOI: 10.1016/j.copbio.2012.03.008  0.44
2012 Chesters C, Wilding M, Goodall M, Micklefield J. Thermal bifunctionality of bacterial phenylalanine aminomutase and ammonia lyase enzymes. Angewandte Chemie (International Ed. in English). 51: 4344-8. PMID 22461423 DOI: 10.1002/anie.201200669  0.44
2012 Dixon N, Robinson CJ, Geerlings T, Duncan JN, Drummond SP, Micklefield J. Orthogonal riboswitches for tuneable coexpression in bacteria. Angewandte Chemie (International Ed. in English). 51: 3620-4. PMID 22383398 DOI: 10.1002/anie.201109106  0.44
2012 Wong LS, Karthikeyan CV, Eichelsdoerfer DJ, Micklefield J, Mirkin CA. A methodology for preparing nanostructured biomolecular interfaces with high enzymatic activity. Nanoscale. 4: 659-66. PMID 22159287 DOI: 10.1039/c1nr11443c  0.44
2012 Wilding M, Goodall M, Micklefield J. 7.19 C-X Bond Formation: Enzymatic Enantioselective Decarboxylative Protonation and C-C Bond Formation Comprehensive Chirality. 7: 402-429. DOI: 10.1016/B978-0-08-095167-6.00724-2  0.44
2011 Woolard J, Vousden W, Moss SJ, Krishnakumar A, Gammons MV, Nowak DG, Dixon N, Micklefield J, Spannhoff A, Bedford MT, Gregory MA, Martin CJ, Leadlay PF, Zhang MQ, Harper SJ, et al. Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms. Chemical Science (Royal Society of Chemistry : 2010). 2011: 273-278. PMID 22822423 DOI: 10.1039/C0SC00297F  0.44
2011 Worthington RJ, Micklefield J. Biophysical and cellular-uptake properties of mixed-sequence pyrrolidine-amide oligonucleotide mimics. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 14429-41. PMID 22076794 DOI: 10.1002/chem.201101950  0.44
2011 Ahmad SA, Wong LS, ul-Haq E, Hobbs JK, Leggett GJ, Micklefield J. Protein micro- and nanopatterning using aminosilanes with protein-resistant photolabile protecting groups. Journal of the American Chemical Society. 133: 2749-59. PMID 21302963 DOI: 10.1021/ja1103662  0.44
2011 Lewis RA, Nunns L, Thirlway J, Carroll K, Smith CP, Micklefield J. Active site modification of the β-ketoacyl-ACP synthase FabF3 of Streptomyces coelicolor affects the fatty acid chain length of the CDA lipopeptides. Chemical Communications (Cambridge, England). 47: 1860-2. PMID 21135931 DOI: 10.1039/c0cc03444d  0.44
2011 Ul-Haq E, Liu Z, Zhang Y, Alang Ahmad SA, Wong LS, Hobbs JK, Leggett GJ, Micklefield J, Roberts CJ, Weaver JMR. The Snomipede: A parallel platform for scanning near-field photolithography Journal of Materials Research. 26: 2997-3008. DOI: 10.1557/jmr.2011.370  0.44
2010 ul Haq E, Liu Z, Zhang Y, Ahmad SA, Wong LS, Armes SP, Hobbs JK, Leggett GJ, Micklefield J, Roberts CJ, Weaver JM. Parallel scanning near-field photolithography: the snomipede. Nano Letters. 10: 4375-80. PMID 20945880 DOI: 10.1021/nl1018782  0.44
2010 Wong LS, Janusz SJ, Sun S, Leggett GJ, Micklefield J. Nanoscale biomolecular structures on self-assembled monolayers generated from modular pegylated disulfides. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 12234-43. PMID 20839371 DOI: 10.1002/chem.200902439  0.44
2010 Wong LS, Okrasa K, Micklefield J. Site-selective immobilisation of functional enzymes on to polystyrene nanoparticles. Organic & Biomolecular Chemistry. 8: 782-7. PMID 20135034 DOI: 10.1039/b916773k  0.44
2010 Dixon N, Duncan JN, Geerlings T, Dunstan MS, McCarthy JE, Leys D, Micklefield J. Reengineering orthogonally selective riboswitches. Proceedings of the National Academy of Sciences of the United States of America. 107: 2830-5. PMID 20133756 DOI: 10.1073/pnas.0911209107  0.44
2010 Bell NM, Wong R, Micklefield J. A non-enzymatic, DNA template-directed morpholino primer extension approach. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 2026-30. PMID 20087911 DOI: 10.1002/chem.200902237  0.44
2009 Bell NM, Micklefield J. Chemical modification of oligonucleotides for therapeutic, bioanalytical and other applications. Chembiochem : a European Journal of Chemical Biology. 10: 2691-703. PMID 19739190 DOI: 10.1002/cbic.200900341  0.44
2009 Okrasa K, Levy C, Wilding M, Goodall M, Baudendistel N, Hauer B, Leys D, Micklefield J. Structure-guided directed evolution of alkenyl and arylmalonate decarboxylases. Angewandte Chemie (International Ed. in English). 48: 7691-4. PMID 19739187 DOI: 10.1002/anie.200904112  0.44
2009 Wong LS, Khan F, Micklefield J. Selective covalent protein immobilization: strategies and applications. Chemical Reviews. 109: 4025-53. PMID 19572643 DOI: 10.1021/cr8004668  0.44
2009 Wilkinson B, Micklefield J. Chapter 14. Biosynthesis of nonribosomal peptide precursors. Methods in Enzymology. 458: 353-78. PMID 19374990 DOI: 10.1016/S0076-6879(09)04814-9  0.44
2009 Ahmad SA, Wong LS, ul-Haq E, Hobbs JK, Leggett GJ, Micklefield J. Micrometer- and nanometer-scale photopatterning using 2-nitrophenylpropyloxycarbonyl-protected aminosiloxane monolayers. Journal of the American Chemical Society. 131: 1513-22. PMID 19173668 DOI: 10.1021/ja807612y  0.44
2009 Micklefield J. Biosynthesis and biosynthetic engineering of calcium-dependent lipopeptide antibiotics Pure and Applied Chemistry. 81: 1065-1074. DOI: 10.1351/PAC-CON-08-08-29  0.44
2009 Ball AJ, Corr S, Micklefield J. Lipase-catalysed kinetic resolutions of secondary alcohols in pressurised liquid hydrofluorocarbons Tetrahedron Letters. 50: 3543-3546. DOI: 10.1016/j.tetlet.2009.03.037  0.44
2008 Wong LS, Thirlway J, Micklefield J. Direct site-selective covalent protein immobilization catalyzed by a phosphopantetheinyl transferase. Journal of the American Chemical Society. 130: 12456-64. PMID 18722432 DOI: 10.1021/ja8030278  0.44
2008 Okrasa K, Levy C, Hauer B, Baudendistel N, Leys D, Micklefield J. Structure and mechanism of an unusual malonate decarboxylase and related racemases. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 6609-13. PMID 18576402 DOI: 10.1002/chem.200800918  0.44
2008 Amir-Heidari B, Thirlway J, Micklefield J. Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues. Organic & Biomolecular Chemistry. 6: 975-8. PMID 18327318 DOI: 10.1039/b718766c  0.44
2008 Vaidyanathan S, Fletcher JS, Goodacre R, Lockyer NP, Micklefield J, Vickerman JC. Subsurface biomolecular imaging of Streptomyces coelicolor using secondary ion mass spectrometry. Analytical Chemistry. 80: 1942-51. PMID 18290669 DOI: 10.1021/ac701921e  0.44
2008 Worthington RJ, Bell NM, Wong R, Micklefield J. RNA-selective cross-pairing of backbone-extended pyrrolidine-amide oligonucleotide mimics (bePOMs). Organic & Biomolecular Chemistry. 6: 92-103. PMID 18075653 DOI: 10.1039/b714580m  0.44
2007 Dixon N, Wong LS, Geerlings TH, Micklefield J. Cellular targets of natural products. Natural Product Reports. 24: 1288-310. PMID 18033580 DOI: 10.1039/b616808f  0.44
2007 Powell A, Borg M, Amir-Heidari B, Neary JM, Thirlway J, Wilkinson B, Smith CP, Micklefield J. Engineered biosynthesis of nonribosomal lipopeptides with modified fatty acid side chains. Journal of the American Chemical Society. 129: 15182-91. PMID 18020333 DOI: 10.1021/ja074331o  0.44
2007 Amir-Heidari B, Micklefield J. NMR confirmation that tryptophan dehydrogenation occurs with syn stereochemistry during the biosynthesis of CDA in Streptomyces coelicolor. The Journal of Organic Chemistry. 72: 8950-3. PMID 17929869 DOI: 10.1021/jo701660v  0.44
2007 Mahlert C, Kopp F, Thirlway J, Micklefield J, Marahiel MA. Stereospecific enzymatic transformation of alpha-ketoglutarate to (2S,3R)-3-methyl glutamate during acidic lipopeptide biosynthesis. Journal of the American Chemical Society. 129: 12011-8. PMID 17784761 DOI: 10.1021/ja074427i  0.44
2007 Powell A, Al Nakeeb M, Wilkinson B, Micklefield J. Precursor-directed biosynthesis of nonribosomal lipopeptides with modified glutamate residues. Chemical Communications (Cambridge, England). 2683-5. PMID 17594019 DOI: 10.1039/b706224a  0.44
2007 Wilkinson B, Micklefield J. Mining and engineering natural-product biosynthetic pathways. Nature Chemical Biology. 3: 379-86. PMID 17576425 DOI: 10.1038/nchembio.2007.7  0.44
2007 Amir-Heidari B, Thirlway J, Micklefield J. Stereochemical course of tryptophan dehydrogenation during biosynthesis of the calcium-dependent lipopeptide antibiotics. Organic Letters. 9: 1513-6. PMID 17355143 DOI: 10.1021/ol0701619  0.44
2007 Neary JM, Powell A, Gordon L, Milne C, Flett F, Wilkinson B, Smith CP, Micklefield J. An asparagine oxygenase (AsnO) and a 3-hydroxyasparaginyl phosphotransferase (HasP) are involved in the biosynthesis of calcium-dependent lipopeptide antibiotics. Microbiology (Reading, England). 153: 768-76. PMID 17322197 DOI: 10.1099/mic.0.2006/002725-0  0.44
2007 Worthington RJ, O'Rourke AP, Morral J, Tan TH, Micklefield J. Mixed-sequence pyrrolidine-amide oligonucleotide mimics: Boc(Z) synthesis and DNA/RNA binding properties. Organic & Biomolecular Chemistry. 5: 249-59. PMID 17205168 DOI: 10.1039/b613386j  0.44
2007 Tan TH, Worthington RJ, Pritchard RG, Morral J, Micklefield J. Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA/RNA binding properties. Organic & Biomolecular Chemistry. 5: 239-48. PMID 17205167 DOI: 10.1039/b613384n  0.44
2006 Milne C, Powell A, Jim J, Al Nakeeb M, Smith CP, Micklefield J. Biosynthesis of the (2S,3R)-3-methyl glutamate residue of nonribosomal lipopeptides. Journal of the American Chemical Society. 128: 11250-9. PMID 16925444 DOI: 10.1021/ja062960c  0.44
2006 Khan AI, Tan TH, Micklefield J. Stereospecific backbone methylation of pyrrolidine-amide oligonucleotide mimics (POM). Chemical Communications (Cambridge, England). 1436-8. PMID 16550292 DOI: 10.1039/b518171b  0.44
2005 Micklefield J. Nature's protection racket. Chemistry & Biology. 12: 611-3. PMID 15975504 DOI: 10.1016/j.chembiol.2005.06.002  0.44
2005 Beadham I, Micklefield J. Reagents for carbonyl methylenation in organic synthesis Current Organic Synthesis. 2: 231-259. DOI: 10.2174/1570179053545396  0.44
2004 Kim HB, Smith CP, Micklefield J, Mavituna F. Metabolic flux analysis for calcium dependent antibiotic (CDA) production in Streptomyces coelicolor. Metabolic Engineering. 6: 313-25. PMID 15491861 DOI: 10.1016/j.ymben.2004.04.001  0.44
2004 Saul S, Corr S, Micklefield J. Biotransformations in low-boiling hydrofluorocarbon solvents. Angewandte Chemie (International Ed. in English). 43: 5519-23. PMID 15484235 DOI: 10.1002/anie.200460082  0.44
2004 Micklefield J. Daptomycin structure and mechanism of action revealed. Chemistry & Biology. 11: 887-8. PMID 15271343 DOI: 10.1016/j.chembiol.2004.07.001  0.44
2004 Ball LJ, Goult CM, Donarski JA, Micklefield J, Ramesh V. NMR structure determination and calcium binding effects of lipopeptide antibiotic daptomycin. Organic & Biomolecular Chemistry. 2: 1872-8. PMID 15227539 DOI: 10.1039/b402722a  0.44
2004 Uguru GC, Milne C, Borg M, Flett F, Smith CP, Micklefield J. Active-site modifications of adenylation domains lead to hydrolysis of upstream nonribosomal peptidyl thioester intermediates. Journal of the American Chemical Society. 126: 5032-3. PMID 15099062 DOI: 10.1021/ja048778y  0.44
2004 Tan TH, Hickman DT, Morral J, Beadham IG, Micklefield J. Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM). Chemical Communications (Cambridge, England). 516-7. PMID 14973585 DOI: 10.1039/b315768g  0.44
2004 Li H, Williams P, Micklefield J, Gardiner JM, Stephens G. A dynamic combinatorial screen for novel imine reductase activity Tetrahedron. 60: 753-758. DOI: 10.1016/j.tet.2003.10.114  0.44
2003 Hickman DT, Tan TH, Morral J, King PM, Cooper MA, Micklefield J. Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM). Organic & Biomolecular Chemistry. 1: 3277-92. PMID 14584791 DOI: 10.1039/b306156f  0.44
2002 Hojati Z, Milne C, Harvey B, Gordon L, Borg M, Flett F, Wilkinson B, Sidebottom PJ, Rudd BA, Hayes MA, Smith CP, Micklefield J. Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor. Chemistry & Biology. 9: 1175-87. PMID 12445768 DOI: 10.1016/S1074-5521(02)00252-1  0.44
2002 Fettes KJ, Howard N, Hickman DT, Adah S, Player MR, Torrence PF, Micklefield J. Synthesis and nucleic-acid-binding properties of sulfamide- and 3′-N-sulfamate-modified DNA Journal of the Chemical Society. Perkin Transactions 1. 485-495.  0.44
2001 Hickman DT, King PM, Slater JM, Cooper MA, Micklefield J. Kinetically selective binding of single stranded RNA over DNA by a pyrrolidine-amide oligonucleotide mimic (POM). Nucleosides, Nucleotides & Nucleic Acids. 20: 1169-72. PMID 11562979 DOI: 10.1081/NCN-100002512  0.44
2001 Micklefield J. Backbone modification of nucleic acids: synthesis, structure and therapeutic applications. Current Medicinal Chemistry. 8: 1157-79. PMID 11472234  0.44
2000 Hickman DT, King PM, Cooper MA, Slater JM, Micklefield J. Unusual RNA and DNA binding properties of a novel pyrrolidine-amide oligonucleotide mimic (POM) Chemical Communications. 2251-2252.  0.44
2000 Fettes KJ, Howard N, Hickman DT, Adah SA, Player MR, Torrence PF, Micklefield J. Replacement of the phosphodiester linkage in dna with sulfamide and 3'- N-sulfamate groups Chemical Communications. 765-766.  0.44
1998 Micklefield J, Fettes KJ. Sulfamide replacement of the phosphodiester linkage in dinucleotides: Synthesis and conformational analysis Tetrahedron. 54: 2129-2142. DOI: 10.1016/S0040-4020(97)10421-5  0.44
1998 Lau KT, Micklefield J, Slater JM. The optimisation of sorption sensor arrays for use in ambient conditions Sensors and Actuators, B: Chemical. 50: 69-79.  0.44
1997 Micklefield J, Fettes KJ. Synthesis of sulfamide linked dinucleotide analogues Tetrahedron Letters. 38: 5387-5390. DOI: 10.1016/S0040-4039(97)01179-9  0.44
1997 Micklefield J, Beckmann M, Mackman RL, Block MH, Leeper FJ, Battersby AR. Haem d1: Stereoselective synthesis of the macrocycle to establish its absolute configuration as 2R,7R Journal of the Chemical Society - Perkin Transactions 1. 2123-2138.  0.44
1997 Mackman RL, Micklefield J, Block MH, Leeper FJ, Battersby AR. Haem d1: Development of a new coupling procedure leading to the synthesis of isobacteriochlorins Journal of the Chemical Society - Perkin Transactions 1. 2111-2122.  0.44
1995 Micklefield J, Harris KJ, Gröger S, Mocek U, Hilbi H, Dimroth P, Floss HG. Stereochemical course of malonate decarboxylation in Malonomonas rubra Journal of the American Chemical Society. 117: 1153-1154.  0.44
1993 Micklefield J, MacKman RL, Aucken CJ, Beckmann M, Block MH, Leeper FJ, Battersby AR. A novel stereoselective synthesis of the macrocycle of haem d1 that establishes its absolute configuration as 2R,7R Journal of the Chemical Society, Chemical Communications. 275-277. DOI: 10.1039/C39930000275  0.44
1992 Micklefield J, Block MH, Battersby AR. Alkylation and acylation of 5-phenylsulphonyl- and 5-cyanobutyrolactones Tetrahedron. 48: 7519-7526. DOI: 10.1016/S0040-4020(01)90365-5  0.44
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