cached image

Karl A. Scheidt, Ph.D. - Publications

Affiliations: 
2002- Chemistry Northwestern University, Evanston, IL 
Area:
Organic, Synthetic, Bio-Organic, Medicinal Chemistry, Chemical Biology, Catalysis, Materials
Website:
http://www.chemistry.northwestern.edu/faculty/karl-scheidt.html

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bayly AA, McDonald BR, Mrksich M, Scheidt KA. High-throughput photocapture approach for reaction discovery. Proceedings of the National Academy of Sciences of the United States of America. PMID 32482866 DOI: 10.1073/pnas.2003347117  0.64
2020 Scheidt K, Davies A, Fitzpatrick K, Betori R. Combined Photoredox and Carbene Catalysis for the Synthesis of Ketones from Carboxylic Acids. Angewandte Chemie (International Ed. in English). PMID 32119162 DOI: 10.1002/anie.202001824  0.44
2020 Betori RC, Liu Y, Mishra RK, Cohen SB, Kron SJ, Scheidt KA. Targeted Covalent Inhibition of Telomerase. Acs Chemical Biology. PMID 32017522 DOI: 10.1021/acschembio.9b00945  0.84
2020 Miller ER, Hovey MT, Scheidt KA. A Concise, Enantioselective Approach for the Synthesis of Yohimbine Alkaloids. Journal of the American Chemical Society. PMID 31951394 DOI: 10.1021/jacs.9b12319  0.92
2019 Mishra RK, Deibler KK, Clutter MR, Vagadia PP, O'Connor M, Schiltz GE, Bergan R, Scheidt KA. Modeling MEK4 Kinase Inhibitors Through Perturbed Electrostatic Potential (ESP) Charges. Journal of Chemical Information and Modeling. PMID 31566378 DOI: 10.1021/acs.jcim.9b00490  0.84
2019 Scheidt K, Betori R, May C. Combined Photoredox/Enzymatic C-H Benzylic Hydroxylations Rick C. Betoria, Catherine M. Maya, Karl A. Scheidt*a. Angewandte Chemie (International Ed. in English). PMID 31465617 DOI: 10.1002/anie.201909426  0.44
2019 Scheidt K, Squitieri R, Fitzpatrick K, Jaworski A. Synthesis and Evaluation of Azolium-Based Halogen Bond Donors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31112630 DOI: 10.1002/chem.201902298  0.44
2019 Betori RC, McDonald BR, Scheidt KA. Reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis. Chemical Science. 10: 3353-3359. PMID 30996923 DOI: 10.1039/c9sc00302a  0.64
2019 Scheidt K, Lee A, Zhu J, Feoktistova T, Brueckner A, Cheong P. Carbene-Catalyzed Enantioselective Decarboxylative Annulations to Access Dihydrobenzoxazinones and Quinolones. Angewandte Chemie (International Ed. in English). PMID 30843323 DOI: 10.1002/anie.201900600  1
2019 Scheidt K, Deibler KK, Schiltz GE, Clutter MR, Mishra RK, Vagadia PP, O'Connor M, George MD, Gordon R, Fowler G, Bergan R. Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors. Chemmedchem. PMID 30707493 DOI: 10.1002/cmdc.201900019  0.84
2018 Lopez SS, Jaworski AA, Scheidt KA. NHC-Catalyzed Formal [2+2] Annulations of Allenoates for the Synthesis of Substituted Oxetanes. The Journal of Organic Chemistry. PMID 30427675 DOI: 10.1021/acs.joc.8b02464  0.56
2018 Scheidt K, Maskeri M, O'Connor M, Jaworski AA, Davies A. A Cooperative Hydrogen Bond Donor/Brønsted Acid System for the Enantioselective Synthesis of Tetrahydropyrans. Angewandte Chemie (International Ed. in English). PMID 30380196 DOI: 10.1002/anie.201811383  0.56
2018 McDonald BR, Scheidt KA. Intermolecular Reductive Couplings of Arylidene Malonates via Lewis Acid/Photoredox Cooperative Catalysis. Organic Letters. PMID 30346177 DOI: 10.1021/acs.orglett.8b02893  0.64
2018 Schwamb CB, Fitzpatrick KP, Brueckner AC, Richardson HC, Cheong PH, Scheidt KA. Correction to "Enantioselective Synthesis of α-Amidoboronates Catalyzed by Planar-Chiral NHC-Cu(I) Complexes". Journal of the American Chemical Society. PMID 30299942 DOI: 10.1021/jacs.8b10073  0.84
2018 Schwamb CB, Fitzpatrick KP, Brueckner AC, Richardson HC, Cheong PH, Scheidt KA. Enantioselective Synthesis of α-Amidoboronates Catalyzed by Planar-Chiral NHC-Cu(I) Complexes. Journal of the American Chemical Society. PMID 30102526 DOI: 10.1021/jacs.8b05045  0.84
2018 Xu L, Gordon R, Farmer R, Pattanayak A, Binkowski A, Huang X, Avram M, Krishna S, Voll E, Pavese J, Chavez J, Bruce J, Mazar A, Nibbs A, Anderson W, ... ... Scheidt K, et al. Precision therapeutic targeting of human cancer cell motility. Nature Communications. 9: 2454. PMID 29934502 DOI: 10.1038/s41467-018-04465-5  0.68
2018 Lee A, Betori R, Crane E, Scheidt KA. An Enantioselective Cross Dehydrogenative Coupling Catalysis Approach to Substituted Tetrahydropyrans. Journal of the American Chemical Society. PMID 29714480 DOI: 10.1021/jacs.8b03063  1
2018 Uno BE, Dicken RD, Redfern LR, Stern CM, Krzywicki GG, Scheidt KA. Calcium(ii)-catalyzed enantioselective conjugate additions of amines. Chemical Science. 9: 1634-1639. PMID 29675209 DOI: 10.1039/c7sc05205g  0.72
2018 Murauski KJR, Jaworski AA, Scheidt KA. A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones. Chemical Society Reviews. PMID 29372207 DOI: 10.1039/c7cs00386b  0.8
2017 Murauski KJR, Walden DM, Cheong PH, Scheidt KA. A Cooperative Ternary Catalysis System for Asymmetric Lactonizations of α-Ketoesters. Advanced Synthesis & Catalysis. 359: 3713-3719. PMID 30473657 DOI: 10.1002/adsc.201701015  0.8
2017 Betori RC, Miller ER, Scheidt KA. A Biocatalytic Route to Highly Enantioenriched β-Hydroxydioxinones. Advanced Synthesis & Catalysis. 359: 1131-1137. PMID 29104524 DOI: 10.1002/adsc.201700095  0.32
2017 Walden DM, Jaworski AA, Johnston RC, Hovey MT, Baker HV, Meyer MP, Scheidt KA, Cheong PH. On the Formation of Aza-ortho-quinone Methides Under Room Temperature Conditions: Cs2CO3 Effect. The Journal of Organic Chemistry. PMID 28649838 DOI: 10.1021/acs.joc.7b00697  0.96
2017 Scheidt K, Hovey T, Cohen D, Walden D, Cheong P. A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products. Angewandte Chemie (International Ed. in English). PMID 28632913 DOI: 10.1002/anie.201705308  0.36
2017 Wang MH, Barsoum D, Schwamb CB, Cohen DT, Goess BC, Riedrich M, Chan A, Maki BE, Mishra RK, Scheidt KA. Catalytic, Enantioselective β-Protonation through a Cooperative Activation Strategy. The Journal of Organic Chemistry. PMID 28441019 DOI: 10.1021/acs.joc.7b00334  1
2017 Deibler KK, Mishra RK, Clutter MR, Antanasijevic A, Bergan R, Caffrey M, Scheidt KA. A Chemical Probe Strategy for Interrogating Inhibitor Selectivity Across the MEK kinase Family. Acs Chemical Biology. PMID 28263556 DOI: 10.1021/acschembio.6b01060  0.84
2016 Wang MH, Scheidt KA. Cooperative Catalysis and Activation with N-Heterocyclic Carbenes. Angewandte Chemie (International Ed. in English). PMID 27763702 DOI: 10.1002/anie.201605319  0.84
2016 Jaworski AA, Scheidt KA. Emerging Roles of in Situ Generated Quinone Methides in Metal-Free Catalysis. The Journal of Organic Chemistry. PMID 27513764 DOI: 10.1021/acs.joc.6b01367  0.56
2016 Sharma HA, Todd Hovey M, Scheidt KA. Azaindole synthesis through dual activation catalysis with N-heterocyclic carbenes. Chemical Communications (Cambridge, England). PMID 27363788 DOI: 10.1039/c6cc04735a  1
2016 Hall EA, Redfern LR, Wang MH, Scheidt KA. Lewis Acid Activation of a Hydrogen Bond Donor Metal-Organic Framework for Catalysis Acs Catalysis. 6: 3248-3252. DOI: 10.1021/acscatal.6b00424  1
2015 Zhu J, Mishra RK, Schiltz G, Makanji Y, Scheidt KA, Mazar A, Woodruff TK. Virtual High Throughput Screening to identify novel activin antagonists. Journal of Medicinal Chemistry. PMID 26098096 DOI: 10.1021/acs.jmedchem.5b00753  1
2015 Wang MH, Cohen DT, Schwamb CB, Mishra RK, Scheidt KA. Enantioselective β-Protonation by a Cooperative Catalysis Strategy. Journal of the American Chemical Society. 137: 5891-4. PMID 25929160 DOI: 10.1021/jacs.5b02887  1
2015 Younai A, Zeng BS, Meltzer HY, Scheidt KA. Enantioselective Syntheses of Heteroyohimbine Natural Products: A Unified Approach through Cooperative Catalysis. Angewandte Chemie (International Ed. in English). 54: 6900-4. PMID 25914164 DOI: 10.1002/anie.201502011  1
2015 McDonald BR, Scheidt KA. Pyranone natural products as inspirations for catalytic reaction discovery and development. Accounts of Chemical Research. 48: 1172-83. PMID 25742935 DOI: 10.1021/ar5004576  1
2015 Lee A, Scheidt KA. N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins. Chemical Communications (Cambridge, England). 51: 3407-10. PMID 25623173 DOI: 10.1039/c4cc09590a  1
2015 Check CT, Jang KP, Schwamb CB, Wong AS, Wang MH, Scheidt KA. Ferrocene-based planar chiral imidazopyridinium salts for catalysis. Angewandte Chemie (International Ed. in English). 54: 4264-8. PMID 25619772 DOI: 10.1002/anie.201410118  1
2015 Cohen DT, Johnston RC, Rosson NT, Cheong PH, Scheidt KA. Functionalized cyclopentenes through a tandem NHC-catalyzed dynamic kinetic resolution and ambient temperature decarboxylation: mechanistic insight and synthetic application. Chemical Communications (Cambridge, England). 51: 2690-3. PMID 25575249 DOI: 10.1039/c4cc09308a  1
2015 McDonald BR, Nibbs AE, Scheidt KA. A biomimetic strategy to access the silybins: total synthesis of (-)-isosilybin A. Organic Letters. 17: 98-101. PMID 25517432 DOI: 10.1021/ol503303w  1
2015 Lombardo VM, Dhulst EA, Leitsch EK, Wilmot N, Heath WH, Gies AP, Miller MD, Torkelson JM, Scheidt KA. Cooperative catalysis of cyclic carbonate ring opening: Application towards non-isocyanate polyurethane materials European Journal of Organic Chemistry. 2015: 2791-2795. DOI: 10.1002/ejoc.201500313  1
2014 Zeng BS, Yu X, Siu PW, Scheidt KA. Catalytic enantioselective synthesis of 2-aryl-chromenes. Chemical Science (Royal Society of Chemistry : 2010). 5: 2277-2281. PMID 25705366 DOI: 10.1039/C4SC00423J  1
2014 Liu K, Hovey MT, Scheidt KA. A Cooperative N-Heterocyclic Carbene/Palladium Catalysis System. Chemical Science (Royal Society of Chemistry : 2010). 5: 4026-4031. PMID 25364496 DOI: 10.1039/C4SC01536C  1
2014 Johnston RC, Cohen DT, Eichman CC, Scheidt KA, Cheong PH. Catalytic Kinetic Resolution of a Dynamic Racemate: Highly Stereoselective β-Lactone Formation by N-Heterocyclic Carbene Catalysis. Chemical Science (Royal Society of Chemistry : 2010). 5: 1974-1982. PMID 25045464 DOI: 10.1039/C4SC00317A  1
2014 Hovey MT, Check CT, Sipher AF, Scheidt KA. N-heterocyclic-carbene-catalyzed synthesis of 2-aryl indoles. Angewandte Chemie (International Ed. in English). 53: 9603-7. PMID 25044815 DOI: 10.1002/anie.201405035  1
2014 Lee A, Younai A, Price CK, Izquierdo J, Mishra RK, Scheidt KA. Enantioselective annulations for dihydroquinolones by in situ generation of azolium enolates. Journal of the American Chemical Society. 136: 10589-92. PMID 25017004 DOI: 10.1021/ja505880r  1
2014 Lee A, Scheidt KA. A cooperative N-heterocyclic carbene/chiral phosphate catalysis system for allenolate annulations. Angewandte Chemie (International Ed. in English). 53: 7594-8. PMID 24895280 DOI: 10.1002/anie.201403446  1
2014 Lukas TJ, Schiltz GE, Arrat H, Scheidt K, Siddique T. Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression. Bioorganic & Medicinal Chemistry Letters. 24: 1532-7. PMID 24560539 DOI: 10.1016/j.bmcl.2014.01.078  1
2014 Jang KP, Hutson GE, Johnston RC, McCusker EO, Cheong PH, Scheidt KA. Asymmetric homoenolate additions to acyl phosphonates through rational design of a tailored N-heterocyclic carbene catalyst. Journal of the American Chemical Society. 136: 76-9. PMID 24299299 DOI: 10.1021/ja410932t  1
2014 Scheidt KA, O'Bryan EA. Acyloin Coupling Reactions Comprehensive Organic Synthesis: Second Edition. 3: 621-655. DOI: 10.1016/B978-0-08-097742-3.00317-7  1
2013 Krishna SN, Luan CH, Mishra RK, Xu L, Scheidt KA, Anderson WF, Bergan RC. A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4. Plos One. 8: e81504. PMID 24339940 DOI: 10.1371/journal.pone.0081504  1
2013 McCusker EO, Scheidt KA. Enantioselective N-heterocyclic carbene catalyzed annulation reactions with imidazolidinones. Angewandte Chemie (International Ed. in English). 52: 13616-20. PMID 24249661 DOI: 10.1002/anie.201307292  1
2013 Lombardo VM, Thomas CD, Scheidt KA. A tandem isomerization/prins strategy: iridium(III)/Brønsted acid cooperative catalysis. Angewandte Chemie (International Ed. in English). 52: 12910-4. PMID 24218144 DOI: 10.1002/anie.201306462  1
2013 Siu PW, Brown ZJ, Farha OK, Hupp JT, Scheidt KA. A mixed dicarboxylate strut approach to enhancing catalytic activity of a de novo urea derivative of metal-organic framework UiO-67. Chemical Communications (Cambridge, England). 49: 10920-2. PMID 24132049 DOI: 10.1039/c3cc47177b  1
2013 Farmer RL, Scheidt KA. A Concise Enantioselective Synthesis and Cytotoxic Evaluation of the Anticancer Rotenoid Deguelin Enabled by a Tandem Knoevenagel/Conjugate Addition/Decarboxylation Sequence. Chemical Science (Royal Society of Chemistry : 2010). 4: 3304-3309. PMID 24101971 DOI: 10.1039/C3SC50424G  1
2013 Katz MJ, Brown ZJ, Colón YJ, Siu PW, Scheidt KA, Snurr RQ, Hupp JT, Farha OK. A facile synthesis of UiO-66, UiO-67 and their derivatives. Chemical Communications (Cambridge, England). 49: 9449-51. PMID 24008272 DOI: 10.1039/c3cc46105j  1
2013 Izquierdo J, Orue A, Scheidt KA. A dual Lewis base activation strategy for enantioselective carbene-catalyzed annulations. Journal of the American Chemical Society. 135: 10634-7. PMID 23829462 DOI: 10.1021/ja405833m  1
2013 Lalonde MB, Getman RB, Lee JY, Roberts JM, Sarjeant AA, Scheidt KA, Georgiev PA, Embs JP, Eckert J, Farha OK, Snurr RQ, Hupp JT. A zwitterionic metal-organic framework with free carboxylic acid sites that exhibits enhanced hydrogen adsorption energies Crystengcomm. 15: 9408-9414. DOI: 10.1039/c3ce40198g  1
2013 Tenenbaum JM, Morris WJ, Custar DW, Scheidt KA. Exploring prins strategies for the synthesis of okilactomycin Strategies and Tactics in Organic Synthesis. 9: 231-248. DOI: 10.1016/B978-0-08-099362-1.00008-4  1
2013 Cardinal-David B, Scheidt KA. Carbene catalysis: Beyond the benzoin and stetter reactions Topics in Organometallic Chemistry. 44: 233-260. DOI: 10.1007/3418-2012-47  1
2013 Scheidt KA, Phillips EM, Dugal-Tessier J. N-Heterocyclic Carbene-Catalyzed Aldol Desymmetrizations Asymmetric Synthesis Ii: More Methods and Applications. 309-316. DOI: 10.1002/9783527652235.ch39  1
2012 Cohen DT, Scheidt KA. Cooperative Lewis acid/N-heterocyclic carbene catalysis. Chemical Science (Royal Society of Chemistry : 2010). 3: 53-57. PMID 26413259 DOI: 10.1039/C1SC00621E  1
2012 Izquierdo J, Hutson GE, Cohen DT, Scheidt KA. A continuum of progress: applications of N-hetereocyclic carbene catalysis in total synthesis. Angewandte Chemie (International Ed. in English). 51: 11686-98. PMID 23074146 DOI: 10.1002/anie.201203704  1
2012 Nibbs AE, Scheidt KA. Asymmetric Methods for the Synthesis of Flavanones, Chromanones, and Azaflavanones. European Journal of Organic Chemistry. 2012: 449-462. PMID 22876166 DOI: 10.1002/ejoc.201101228  1
2012 Cui J, Chai DI, Miller C, Hao J, Thomas C, Wang J, Scheidt KA, Kozmin SA. Assembly of four diverse heterocyclic libraries enabled by Prins cyclization, Au-catalyzed enyne cycloisomerization, and automated amide synthesis. The Journal of Organic Chemistry. 77: 7435-70. PMID 22860634 DOI: 10.1021/jo301061r  1
2012 Cohen DT, Eichman CC, Phillips EM, Zarefsky ER, Scheidt KA. Catalytic dynamic kinetic resolutions with N-heterocyclic carbenes: asymmetric synthesis of highly substituted β-lactones. Angewandte Chemie (International Ed. in English). 51: 7309-13. PMID 22700327 DOI: 10.1002/anie.201203382  1
2012 Dugal-Tessier J, O'Bryan EA, Schroeder TB, Cohen DT, Scheidt KA. An N-heterocyclic carbene/Lewis acid strategy for the stereoselective synthesis of spirooxindole lactones. Angewandte Chemie (International Ed. in English). 51: 4963-7. PMID 22489096 DOI: 10.1002/anie.201201643  1
2012 Roberts JM, Fini BM, Sarjeant AA, Farha OK, Hupp JT, Scheidt KA. Urea metal-organic frameworks as effective and size-selective hydrogen-bond catalysts. Journal of the American Chemical Society. 134: 3334-7. PMID 22296523 DOI: 10.1021/ja2108118  1
2012 Brekan JA, Chernyak D, White KL, Scheidt KA. Lewis base-promoted carbon-carbon sp 3-sp 3 coupling reactions of α-silyl silylethers Chemical Science. 3: 1205-1210. DOI: 10.1039/c2sc00581f  1
2012 Cohen DT, Scheidt KA. Cooperative Lewis acid/N-heterocyclic carbene catalysis Chemical Science. 3: 53-57. DOI: 10.1039/c1sc00621e  1
2012 Sonntag MD, Klingsporn JM, Garibay LK, Roberts JM, Dieringer JA, Seideman T, Scheidt KA, Jensen L, Schatz GC, Van Duyne RP. Single-molecule tip-enhanced Raman spectroscopy Journal of Physical Chemistry C. 116: 478-483. DOI: 10.1021/jp209982h  1
2012 Lalonde MB, Farha OK, Scheidt KA, Hupp JT. N -heterocyclic carbene-like catalysis by a metal-organic framework material Acs Catalysis. 2: 1550-1554. DOI: 10.1021/cs300260f  1
2011 Atienza RL, Roth HS, Scheidt KA. N-heterocyclic carbene-catalyzed rearrangements of vinyl sulfones. Chemical Science (Royal Society of Chemistry : 2010). 2: 1772-1776. PMID 22448316 DOI: 10.1039/C1SC00194A  1
2011 Atienza RL, Scheidt KA. N-Heterocyclic Carbene-Promoted Rauhut]Currier Reactions between Vinyl Sulfones and α,β-Unsaturated Aldehydes. Australian Journal of Chemistry. 64: 1158-1164. PMID 22399824  1
2011 Crane EA, Zabawa TP, Farmer RL, Scheidt KA. Enantioselective synthesis of (-)-exiguolide by iterative stereoselective dioxinone-directed Prins cyclizations. Angewandte Chemie (International Ed. in English). 50: 9112-5. PMID 21932228 DOI: 10.1002/anie.201102790  1
2011 Wang J, Crane EA, Scheidt KA. Highly stereoselective Brønsted acid catalyzed synthesis of spirooxindole pyrans. Organic Letters. 13: 3086-9. PMID 21591768 DOI: 10.1021/ol200987c  1
2011 Tenenbaum JM, Morris WJ, Custar DW, Scheidt KA. Synthesis of (-)-okilactomycin by a Prins-type fragment-assembly strategy. Angewandte Chemie (International Ed. in English). 50: 5892-5. PMID 21560215 DOI: 10.1002/anie.201102037  1
2011 Kleinman SL, Ringe E, Valley N, Wustholz KL, Phillips E, Scheidt KA, Schatz GC, Van Duyne RP. Single-molecule surface-enhanced Raman spectroscopy of crystal violet isotopologues: theory and experiment. Journal of the American Chemical Society. 133: 4115-22. PMID 21348518 DOI: 10.1021/ja110964d  1
2011 Cohen DT, Cardinal-David B, Scheidt KA. Lewis acid activated synthesis of highly substituted cyclopentanes by the N-heterocyclic carbene catalyzed addition of homoenolate equivalents to unsaturated ketoesters. Angewandte Chemie (International Ed. in English). 50: 1678-82. PMID 21308931 DOI: 10.1002/anie.201005908  1
2011 Cohen DT, Cardinal-David B, Roberts JM, Sarjeant AA, Scheidt KA. NHC-catalyzed/titanium(IV)-mediated highly diastereo- and enantioselective dimerization of enals. Organic Letters. 13: 1068-71. PMID 21271734 DOI: 10.1021/ol103112v  1
2011 Atienza RL, Scheidt KA. N-heterocyclic carbene-promoted rauhutcurrier reactions between vinyl sulfones and α,β-unsaturated aldehydes Australian Journal of Chemistry. 64: 1158-1164. DOI: 10.1071/CH11264  1
2011 Roberts JM, Farha OK, Sarjeant AA, Hupp JT, Scheidt KA. Two azolium rings are better than one: A strategy for controlling catenation and morphology in Zn and Cu metal - Organic frameworks Crystal Growth and Design. 11: 4747-4750. DOI: 10.1021/cg2011309  1
2010 Farmer RL, Biddle MM, Nibbs AE, Huang X, Bergan RC, Scheidt KA. Concise syntheses of the abyssinones and discovery of new inhibitors of prostate cancer and MMP-2 expression. Acs Medicinal Chemistry Letters. 1: 400-405. PMID 21116437 DOI: 10.1021/ml1003102  1
2010 Crane EA, Scheidt KA. Prins-type macrocyclizations as an efficient ring-closing strategy in natural product synthesis. Angewandte Chemie (International Ed. in English). 49: 8316-26. PMID 20931580 DOI: 10.1002/anie.201002809  1
2010 Phillips EM, Riedrich M, Scheidt KA. N-heterocyclic carbene-catalyzed conjugate additions of alcohols. Journal of the American Chemical Society. 132: 13179-81. PMID 20809579 DOI: 10.1021/ja1061196  1
2010 Raup DE, Cardinal-David B, Holte D, Scheidt KA. Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to gamma-lactams. Nature Chemistry. 2: 766-71. PMID 20729898 DOI: 10.1038/nchem.727  1
2010 Scheidt K. Organic chemistry: Amide bonds made in reverse Nature. 465: 1020-1022. PMID 20577201 DOI: 10.1038/4651020a  1
2010 Phillips EM, Roberts JM, Scheidt KA. Catalytic enantioselective total syntheses of bakkenolides I, J, and S: application of a carbene-catalyzed desymmetrization. Organic Letters. 12: 2830-3. PMID 20469924 DOI: 10.1021/ol100938j  1
2010 Cardinal-David B, Raup DE, Scheidt KA. Cooperative N-heterocyclic carbene/Lewis acid catalysis for highly stereoselective annulation reactions with homoenolates. Journal of the American Chemical Society. 132: 5345-7. PMID 20345186 DOI: 10.1021/ja910666n  1
2010 Brekan JA, Reynolds TE, Scheidt KA. Enantioselective synthesis of substituted indanones from silyloxyallenes. Journal of the American Chemical Society. 132: 1472-3. PMID 20085317 DOI: 10.1021/ja909669e  1
2009 Mathies AK, Mattson AE, Scheidt KA. Intermolecular Cross-Acyloin Reactions by Fluoride-Promoted Additions of O-Silyl Thiazolium Carbinols. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2009: 377-383. PMID 21132061 DOI: 10.1055/s-0028-1087555  1
2009 Phillips EM, Wadamoto M, Scheidt KA. Synthesis of Enantioenriched α,α-Disubstituted Cyclopentenes Catalyzed by N-Heterocyclic Carbenes. Synthesis. 4: 687-690. PMID 21085623 DOI: 10.1055/s-0028-1083284  1
2009 Phillips EM, Chan A, Scheidt KA. Discovering New Reactions with N-Heterocyclic Carbene Catalysis. Aldrichimica Acta. 42: 55-66. PMID 21072130  1
2009 Maki BE, Chan A, Phillips EM, Scheidt KA. N-Heterocyclic Carbene-Catalyzed Oxidations. Tetrahedron. 65: 3102-3109. PMID 20161230 DOI: 10.1016/j.tet.2008.10.033  1
2009 Kawanaka Y, Phillips EM, Scheidt KA. N-heterocyclic carbene-catalyzed enantioselective Mannich reactions with alpha-aryloxyacetaldehydes. Journal of the American Chemical Society. 131: 18028-9. PMID 20000857 DOI: 10.1021/ja9094044  1
2009 Lee JY, Roberts JM, Farha OK, Sarjeant AA, Scheidt KA, Hupp JT. Synthesis and gas sorption properties of a metal-azolium framework (MAF) material. Inorganic Chemistry. 48: 9971-3. PMID 19813724 DOI: 10.1021/ic901174p  1
2009 Custar DW, Zabawa TP, Hines J, Crews CM, Scheidt KA. Total synthesis and structure-activity investigation of the marine natural product neopeltolide. Journal of the American Chemical Society. 131: 12406-14. PMID 19663512 DOI: 10.1021/ja904604x  1
2009 Nibbs AE, Baize AL, Herter RM, Scheidt KA. Catalytic asymmetric alkylation of substituted isoflavanones. Organic Letters. 11: 4010-3. PMID 19658430 DOI: 10.1021/ol901676f  1
2009 Maki BE, Patterson EV, Cramer CJ, Scheidt KA. Impact of solvent polarity on N-heterocyclic carbene-catalyzed beta-protonations of homoenolate equivalents. Organic Letters. 11: 3942-5. PMID 19645427 DOI: 10.1021/ol901545m  1
2009 Xu L, Ding Y, Catalona WJ, Yang XJ, Anderson WF, Jovanovic B, Wellman K, Killmer J, Huang X, Scheidt KA, Montgomery RB, Bergan RC. MEK4 function, genistein treatment, and invasion of human prostate cancer cells. Journal of the National Cancer Institute. 101: 1141-55. PMID 19638505 DOI: 10.1093/jnci/djp227  1
2009 Lettan RB, Galliford CV, Woodward CC, Scheidt KA. Amide enolate additions to acylsilanes: in situ generation of unusual and stereoselective homoenolate equivalents. Journal of the American Chemical Society. 131: 8805-14. PMID 19505076 DOI: 10.1021/ja808811u  1
2009 Lee J, Farha OK, Roberts J, Scheidt KA, Nguyen ST, Hupp JT. Metal-organic framework materials as catalysts. Chemical Society Reviews. 38: 1450-9. PMID 19384447 DOI: 10.1039/b807080f  1
2009 Maki BE, Scheidt KA. Single-flask synthesis of N-acylated indoles by catalytic dehydrogenative coupling with primary alcohols. Organic Letters. 11: 1651-4. PMID 19320508 DOI: 10.1021/ol900306v  1
2009 Phillips EM, Wadamoto M, Roth HS, Ott AW, Scheidt KA. NHC-catalyzed reactions of aryloxyacetaldehydes: a domino elimination/conjugate addition/acylation process for the synthesis of substituted coumarins. Organic Letters. 11: 105-8. PMID 19049403 DOI: 10.1021/ol802448c  1
2009 Stokes GY, Buchbinder AM, Gibbs-Davis JM, Scheidt KA, Geiger FM. Chemically diverse environmental interfaces and their reactions with ozone studied by sum frequency generation Vibrational Spectroscopy. 50: 86-98. DOI: 10.1016/j.vibspec.2008.08.003  1
2009 Phillips EM, Chan A, Scheidt KA. Discovering new reactions with N-heterocyclic carbene catalysis Aldrichimica Acta. 42: 55-66.  1
2008 Maki BE, Chan A, Scheidt KA. Protonation of Homoenolate Equivalents Generated by N-Heterocyclic Carbenes. Synthesis. 2008: 1306-1315. PMID 22347730 DOI: 10.1055/s-2008-1072516  1
2008 Gibbs-Davis JM, Kruk JJ, Konek CT, Scheidt KA, Geiger FM. Jammed acid-base reactions at interfaces. Journal of the American Chemical Society. 130: 15444-7. PMID 19006409 DOI: 10.1021/ja804302s  1
2008 Reynolds TE, Binkley MS, Scheidt KA. Highly selective alpha-acylvinyl anion additions to imines. Organic Letters. 10: 5227-30. PMID 18959427 DOI: 10.1021/ol802227t  1
2008 Stokes GY, Buchbinder AM, Gibbs-Davis JM, Scheidt KA, Geiger FM. Heterogeneous ozone oxidation reactions of 1-pentene, cyclopentene, cyclohexene, and a menthenol derivative studied by sum frequency generation. The Journal of Physical Chemistry. A. 112: 11688-98. PMID 18942815 DOI: 10.1021/jp803277s  1
2008 Maki BE, Scheidt KA. N-heterocyclic carbene-catalyzed oxidation of unactivated aldehydes to esters. Organic Letters. 10: 4331-4. PMID 18759433 DOI: 10.1021/ol8018488  0.96
2008 Reynolds TE, Binkley MS, Scheidt KA. Lewis acid-catalyzed conjugate additions of silyloxyallenes: a selective solution to the intermolecular Rauhut-Currier problem. Organic Letters. 10: 2449-52. PMID 18476709 DOI: 10.1021/ol800745q  1
2008 Galliford CV, Scheidt KA. An unusual dianion equivalent from acylsilanes for the synthesis of substituted beta-keto esters. Chemical Communications (Cambridge, England). 1926-8. PMID 18401521 DOI: 10.1039/b801597j  1
2008 Lettan RB, Woodward CC, Scheidt KA. Highly stereoselective synthesis of substituted gamma-lactams from acylsilanes. Angewandte Chemie (International Ed. in English). 47: 2294-7. PMID 18270992 DOI: 10.1002/anie.200705229  1
2008 Chan A, Scheidt KA. Direct amination of homoenolates catalyzed by N-heterocyclic carbenes. Journal of the American Chemical Society. 130: 2740-1. PMID 18260665 DOI: 10.1021/ja711130p  1
2008 Phillips EM, Reynolds TE, Scheidt KA. Highly diastereo- and enantioselective additions of homoenolates to nitrones catalyzed by N-heterocyclic carbenes. Journal of the American Chemical Society. 130: 2416-7. PMID 18232690 DOI: 10.1021/ja710521m  1
2008 Handa M, Scheidt KA, Bossart M, Zheng N, Roush WR. Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment. The Journal of Organic Chemistry. 73: 1031-5. PMID 18163645 DOI: 10.1021/jo702250z  1
2008 Custar DW, Zabawa TP, Scheidt KA. Total synthesis and structural revision of the marine macrolide neopeltolide. Journal of the American Chemical Society. 130: 804-5. PMID 18161979 DOI: 10.1021/ja710080q  1
2007 Dieringer JA, Lettan RB, Scheidt KA, Van Duyne RP. A frequency domain existence proof of single-molecule surface-enhanced Raman spectroscopy. Journal of the American Chemical Society. 129: 16249-56. PMID 18052068 DOI: 10.1021/ja077243c  1
2007 Galliford CV, Scheidt KA. Pyrrolidinyl-spirooxindole natural products as inspirations for the development of potential therapeutic agents. Angewandte Chemie (International Ed. in English). 46: 8748-58. PMID 17943924 DOI: 10.1002/anie.200701342  1
2007 Reynolds TE, Scheidt KA. Catalytic enantioselective alpha-acylvinyl anion reactions of silyloxyallenes. Angewandte Chemie (International Ed. in English). 46: 7806-9. PMID 17849415 DOI: 10.1002/anie.200702818  1
2007 Wadamoto M, Phillips EM, Reynolds TE, Scheidt KA. Enantioselective synthesis of alpha,alpha-disubstituted cyclopentenes by an N-heterocyclic carbene-catalyzed desymmetrization of 1,3-diketones. Journal of the American Chemical Society. 129: 10098-9. PMID 17663558 DOI: 10.1021/ja073987e  1
2007 Evans DA, Fandrick KR, Song HJ, Scheidt KA, Xu R. Enantioselective Friedel-Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes. Journal of the American Chemical Society. 129: 10029-41. PMID 17658808 DOI: 10.1021/ja072976i  1
2007 Reynolds TE, Stern CA, Scheidt KA. N-heterocyclic carbene-initiated alpha-acylvinyl anion reactivity: additions of alpha-hydroxypropargylsilanes to aldehydes. Organic Letters. 9: 2581-4. PMID 17539656 DOI: 10.1021/ol0710515  1
2007 Gibbs-Davis JM, Hayes PL, Scheidt KA, Geiger FM. Anion chelation by amido acid functionalized fused quartz/water interfaces studied by nonlinear optics. Journal of the American Chemical Society. 129: 7175-84. PMID 17497776 DOI: 10.1021/ja068117w  1
2007 Milgram BC, Eskildsen K, Richter SM, Scheidt WR, Scheidt KA. Microwave-assisted Piloty-Robinson synthesis of 3,4-disubstituted pyrroles. The Journal of Organic Chemistry. 72: 3941-4. PMID 17432915 DOI: 10.1021/jo070389+  1
2007 Chan A, Scheidt KA. Highly stereoselective formal [3 + 3] cycloaddition of enals and azomethine imines catalyzed by N-heterocyclic carbenes. Journal of the American Chemical Society. 129: 5334-5. PMID 17407298 DOI: 10.1021/ja0709167  1
2007 Mattson AE, Scheidt KA. Nucleophilic acylation of o-quinone methides: an umpolung strategy for the synthesis of alpha-aryl ketones and benzofurans. Journal of the American Chemical Society. 129: 4508-9. PMID 17378561 DOI: 10.1021/ja068189n  1
2007 Phillips EM, Wadamoto M, Chan A, Scheidt KA. A highly enantioselective intramolecular Michael reaction catalyzed by N-heterocyclic carbenes. Angewandte Chemie (International Ed. in English). 46: 3107-10. PMID 17366506 DOI: 10.1002/anie.200605235  1
2007 Biddle MM, Lin M, Scheidt KA. Catalytic enantioselective synthesis of flavanones and chromanones. Journal of the American Chemical Society. 129: 3830-1. PMID 17348659 DOI: 10.1021/ja070394v  1
2007 Galliford CV, Martenson JS, Stern C, Scheidt KA. A highly diastereoselective, catalytic three-component assembly reaction for the synthesis of spiropyrrolidinyloxindoles. Chemical Communications (Cambridge, England). 631-3. PMID 17264914 DOI: 10.1039/b609155e  1
2007 Galliford CV, Scheidt KA. Catalytic multicomponent reactions for the synthesis of N-aryl trisubstituted pyrroles. The Journal of Organic Chemistry. 72: 1811-3. PMID 17256992 DOI: 10.1021/jo0624086  1
2007 Maki BE, Chan A, Phillips EM, Scheidt KA. Tandem oxidation of allylic and benzylic alcohols to esters catalyzed by N-heterocyclic carbenes. Organic Letters. 9: 371-4. PMID 17217307 DOI: 10.1021/ol062940f  1
2007 Lettan RB, Milgram BC, Scheidt KA. Synthesis of acylsilanes from morpholine amides. Synthesis of 1-(Dimethyl(phenyl)silyl)propan-1-one Organic Syntheses. 84: 22-31. DOI: 10.15227/orgsyn.084.0022  1
2007 Voges AB, Stokes GY, Gibbs-Davis JM, Lettan RB, Bertin PA, Pike RC, Nguyen ST, Scheidt KA, Geiger FM. Insights into heterogeneous atmospheric oxidation chemistry: Development of a tailor-made synthetic model for studying tropospheric surface chemistry Journal of Physical Chemistry C. 111: 1567-1578. DOI: 10.1021/jp065277l  1
2006 Lettan RB, Reynolds TE, Galliford CV, Scheidt KA. Synthesis of tertiary beta-hydroxy amides by enolate additions to acylsilanes. Journal of the American Chemical Society. 128: 15566-7. PMID 17147347 DOI: 10.1021/ja065605v  1
2006 Reynolds TE, Bharadwaj AR, Scheidt KA. Stereoselective Lewis acid-catalyzed alpha-acylvinyl additions. Journal of the American Chemical Society. 128: 15382-3. PMID 17131998 DOI: 10.1021/ja0653674  1
2006 Mattson AE, Bharadwaj AR, Zuhl AM, Scheidt KA. Thiazolium-catalyzed additions of acylsilanes: a general strategy for acyl anion addition reactions. The Journal of Organic Chemistry. 71: 5715-24. PMID 16839153 DOI: 10.1021/jo060699c  1
2006 Mattson AE, Zuhl AM, Reynolds TE, Scheidt KA. Direct nucleophilic acylation of nitroalkenes promoted by a fluoride anion/thiourea combination. Journal of the American Chemical Society. 128: 4932-3. PMID 16608309 DOI: 10.1021/ja056565i  1
2006 Chan A, Scheidt KA. Hydroacylation of activated ketones catalyzed by N-heterocyclic carbenes. Journal of the American Chemical Society. 128: 4558-9. PMID 16594677 DOI: 10.1021/ja060833a  1
2006 Graves CR, Scheidt KA, Nguyen ST. Enantioselective MSPV reduction of ketimines using 2-propanol and (BINOL)Al(III). Organic Letters. 8: 1229-32. PMID 16524310 DOI: 10.1021/ol060110w  1
2005 Myers MC, Bharadwaj AR, Milgram BC, Scheidt KA. Catalytic conjugate additions of carbonyl anions under neutral aqueous conditions. Journal of the American Chemical Society. 127: 14675-80. PMID 16231921 DOI: 10.1021/ja0520161  1
2005 Lettan Ii RB, Scheidt KA. Lewis base-catalyzed additions of alkynes using trialkoxysilylalkynes. Organic Letters. 7: 3227-30. PMID 16018627 DOI: 10.1021/ol051030f  1
2005 Ballweg DM, Miller RC, Gray DL, Scheidt KA. Stereoselective synthesis of alpha-silylamines by the direct addition of silyl anions to activated imines. Organic Letters. 7: 1403-6. PMID 15787517 DOI: 10.1021/ol050244u  1
2005 Morris WJ, Custar DW, Scheidt KA. Stereoselective synthesis of tetrahydropyran-4-ones from dioxinones catalyzed by scandium(III) triflate. Organic Letters. 7: 1113-6. PMID 15760152 DOI: 10.1021/ol050093v  1
2005 Chan A, Scheidt KA. Conversion of alpha,beta-unsaturated aldehydes into saturated esters: an Umpolung reaction catalyzed by nucleophilic carbenes. Organic Letters. 7: 905-8. PMID 15727471 DOI: 10.1021/ol050100f  1
2005 Chernick ET, Ahrens MJ, Scheidt KA, Wasielewski MR. Copper-promoted N-arylations of cyclic imides within six-membered rings: a facile route to arylene-based organic materials. The Journal of Organic Chemistry. 70: 1486-9. PMID 15704992 DOI: 10.1021/jo0481351  1
2004 Mattson AE, Scheidt KA. Catalytic additions of acylsilanes to imines: an acyl anion strategy for the direct synthesis of alpha-amino ketones. Organic Letters. 6: 4363-6. PMID 15524484 DOI: 10.1021/ol0481129  1
2004 Clark CT, Milgram BC, Scheidt KA. Efficient synthesis of acylsilanes using morpholine amides. Organic Letters. 6: 3977-80. PMID 15496078 DOI: 10.1021/ol0483854  1
2004 Bharadwaj AR, Scheidt KA. Catalytic multicomponent synthesis of highly substituted pyrroles utilizing a one-pot sila-Stetter/Paal-Knorr strategy. Organic Letters. 6: 2465-8. PMID 15228305 DOI: 10.1021/ol049044t  1
2004 Mattson AE, Bharadwaj AR, Scheidt KA. The thiazolium-catalyzed Sila-Stetter reaction: conjugate addition of acylsilanes to unsaturated esters and ketones. Journal of the American Chemical Society. 126: 2314-5. PMID 14982429 DOI: 10.1021/ja0318380  1
2004 Clark CT, Lake JF, Scheidt KA. Copper(I)-catalyzed disilylation of alkylidene malonates employing a Lewis base activation strategy. Journal of the American Chemical Society. 126: 84-5. PMID 14709071 DOI: 10.1021/ja038530t  1
2004 Mattson AE, Scheidt KA. Catalytic additions of acylsilanes to imines: An acyl anion strategy for the direct synthesis of α-amino ketones Organic Letters. 6: 4363-4366.  1
2003 Galliford CV, Beenen MA, Nguyen ST, Scheidt KA. Catalytic, three-component assembly reaction for the synthesis of pyrrolidines. Organic Letters. 5: 3487-90. PMID 12967306 DOI: 10.1021/ol035292y  1
2003 Evans DA, Scheidt KA, Fandrick KR, Lam HW, Wu J. Enantioselective indole Friedel--Crafts alkylations catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes. Journal of the American Chemical Society. 125: 10780-1. PMID 12952445 DOI: 10.1021/ja036985c  1
2002 Evans DA, Borg G, Scheidt KA. Remarkably stable tetrahedral intermediates: carbinols from nucleophilic additions to N-acylpyrroles. Angewandte Chemie (International Ed. in English). 41: 3188-91. PMID 12207385 DOI: 10.1002/1521-3773(20020902)41:17<3188::AID-ANIE3188>3.0.CO;2-H  1
2002 Scheidt KA, Bannister TD, Tasaka A, Wendt MD, Savall BM, Fegley GJ, Roush WR. Total synthesis of (-)-bafilomycin A(1). Journal of the American Chemical Society. 124: 6981-90. PMID 12059221 DOI: 10.1021/ja017885e  1
2002 Roush WR, Bannister TD, Wendt MD, VanNieuwenhze MS, Gustin DJ, Dilley GJ, Lane GC, Scheidt KA, Smith WJ. An NMR method for assigning relative stereochemistry to beta-hydroxy ketones deriving from aldol reactions of methyl ketones. The Journal of Organic Chemistry. 67: 4284-9. PMID 12054964 DOI: 10.1021/jo0164148  1
2002 Roush WR, Bannister TD, Wendt MD, Jablonowski JA, Scheidt KA. Studies on the synthesis of bafilomycin A(1): stereochemical aspects of the fragment assembly aldol reaction for construction of the C(13)-C25) segment. The Journal of Organic Chemistry. 67: 4275-83. PMID 12054963 DOI: 10.1021/jo016413f  1
2001 Evans DA, Scheidt KA, Downey CW. Synthesis of (-)-epibatidine. Organic Letters. 3: 3009-12. PMID 11554830 DOI: 10.1021/ol016420q  1
2001 Evans DA, Scheidt KA, Johnston JN, Willis MC. Enantioselective and diastereoselective Mukaiyama-Michael reactions catalyzed by bis(oxazoline) copper(II) complexes. Journal of the American Chemical Society. 123: 4480-91. PMID 11457234 DOI: 10.1021/ja010302g  1
1999 Scheidt KA, Tasaka A, Bannister TD, Wendt MD, Roush WR. Total Synthesis of (-)-Bafilomycin A : Application of Diastereoselective Crotylboration and Methyl Ketone Aldol Reactions. Angewandte Chemie (International Ed. in English). 38: 1652-1655. PMID 29710989 DOI: 10.1002/(SICI)1521-3773(19990601)38:11<1652::AID-ANIE1652>3.0.CO;2-K  0.8
1999 Scheldt KA, Tasaka A, Bannister TD, Wendt MD, Roush WR. Total synthesis of (-)-bafilomycin A1: Application of diastereoselective crotylboration and methyl ketone aldol reactions Angewandte Chemie - International Edition. 38: 1652-1655. DOI: 10.1002/(SICI)1521-3773(19990601)38:11<1652::AID-ANIE1652>3.0.CO;2-K  0.64
1998 Scheidt KA, Roush WR, McKerrow JH, Selzer PM, Hansell E, Rosenthal PJ. Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors. Bioorganic & Medicinal Chemistry. 6: 2477-94. PMID 9925304 DOI: 10.1016/S0968-0896(98)80022-9  1
1998 Roush WR, Gwaltney SL, Cheng J, Scheidt KA, McKerrow JH, Hansell E. Vinyl sulfonate esters and vinyl sulfonamides: Potent, irreversible inhibitors of cysteine proteases [10] Journal of the American Chemical Society. 120: 10994-10995. DOI: 10.1021/ja981792o  1
1998 Scheidt KA, Xu Z, Roush WR, Johannes CW, Houri AF, La DS, Cogan DA, Hofilena GE, Hoveyda AH. Applications of Zr-catalyzed carbomagnesation and Mo-catalyzed macrocyclic ring closing metathesis in asymmetric synthesis. Enantioselective synthesis of Sch 38516 (Fluvirucin B1) Chemtracts. 11: 522-530.  1
Show low-probability matches.