F. Jon Kull - Publications

Chemistry Dartmouth College, Hanover, NH, United States 
Protein crystallography, molecular motors, cellular transport mechanisms, enzyme mechanisms

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Midgett CR, Talbot KM, Day JL, Munson GP, Kull FJ. Structure of the master regulator Rns reveals an inhibitor of enterotoxigenic Escherichia coli virulence regulons. Scientific Reports. 11: 15663. PMID 34341412 DOI: 10.1038/s41598-021-95123-2  0.354
2020 Midgett CR, Swindell RA, Pellegrini M, Kull FJ. Publisher Correction: A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts. Scientific Reports. 10: 12085. PMID 32669662 DOI: 10.1038/S41598-020-69095-8  0.39
2020 D’Ausilio ME, Morriello C, Osika K, Poh B, Provoost A, Schwarz C, Schwarz M, Volchenkov A, Wu A, Kull FJ. Fatty Acid Regulation of Virulence in Vibrio cholerae : A Structural Analysis of Unbound, Ligand‐Bound, and DNA‐Bound ToxT The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09366  0.365
2019 Cruite JT, Kovacikova G, Clark KA, Woodbrey AK, Skorupski K, Kull FJ. Structural basis for virulence regulation in Vibrio cholerae by unsaturated fatty acid components of bile. Communications Biology. 2: 440. PMID 31925318 DOI: 10.1038/s42003-019-0686-x  0.445
2019 Cruite JT, Kovacikova G, Clark KA, Woodbrey AK, Skorupski K, Kull FJ. Structural basis for virulence regulation in by unsaturated fatty acid components of bile. Communications Biology. 2: 440. PMID 31815195 DOI: 10.1038/s42003-019-0686-x  0.788
2018 Cruite J, Succo P, Raychaudhuri S, Kull FJ. Crystal structure of an inactive variant of the quorum-sensing master regulator HapR from the protease-deficient non-O1, non-O139 Vibrio cholerae strain V2. Acta Crystallographica. Section F, Structural Biology Communications. 74: 331-336. PMID 29870016 DOI: 10.1107/S2053230X18006519  0.784
2017 Privett B, Pellegrini M, Kovacikova G, Taylor R, Skorupski K, Mierke DF, Kull FJ. Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae. Biochemistry. PMID 28640592 DOI: 10.1021/Acs.Biochem.7B00337  0.455
2017 Midgett CR, Almagro-Moreno S, Pellegrini M, Taylor RK, Skorupski K, Kull FJ. Bile salts and alkaline pH reciprocally modulate the interaction between the periplasmic domains of Vibrio cholerae ToxR and ToxS. Molecular Microbiology. PMID 28464377 DOI: 10.1111/Mmi.13699  0.358
2017 Woodbrey AK, Onyango EO, Pellegrini M, Kovacikova G, Taylor RK, Gribble GW, Kull FJ. A new class of inhibitors of the AraC family virulence regulator Vibrio cholerae ToxT. Scientific Reports. 7: 45011. PMID 28332578 DOI: 10.1038/Srep45011  0.38
2017 Walker BC, Thompson ME, Kull FJ, Cochran JC. Myosins Active Site Closure via Switch-1 Allosterically Regulates the Motor-Actin Interaction during the ATPase Cycle for Productive Force Generation Biophysical Journal. 112: 266a. DOI: 10.1016/J.Bpj.2016.11.1444  0.628
2015 Shi W, Kovacikova G, Lin W, Taylor RK, Skorupski K, Kull FJ. The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand. Nature Communications. 6: 6032. PMID 25607896 DOI: 10.1038/Ncomms7032  0.501
2014 Cruite J, Succo P, Prasad A, Raychaudhuri A, Raychaudhuri S, Kull FJ. Crystal Structure of an Inactive Variant of the Vibrio Cholerae Quorum-Sensing Master Regulator HapR Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.329  0.802
2014 Day J, Kovacikova G, Taylor RK, Kull FJ. Unsaturated Fatty Acid Regulation of AraC/XylS Transcription Factors Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.2779  0.398
2013 Cochran JC, Thompson ME, Kull FJ. Metal switch-controlled myosin II from Dictyostelium discoideum supports closure of nucleotide pocket during ATP binding coupled to detachment from actin filaments. The Journal of Biological Chemistry. 288: 28312-23. PMID 23960071 DOI: 10.1074/Jbc.M113.466045  0.636
2013 Cochran JC, Kull FJ. A molecular motor finds its track. Nature Structural & Molecular Biology. 20: 920-1. PMID 23912357 DOI: 10.1038/Nsmb.2644  0.38
2013 Kull FJ, Endow SA. Force generation by kinesin and myosin cytoskeletal motor proteins. Journal of Cell Science. 126: 9-19. PMID 23487037 DOI: 10.1242/Jcs.103911  0.408
2013 Thompson ME, Heimsath EG, Gauvin TJ, Higgs HN, Kull FJ. FMNL3 FH2-actin structure gives insight into formin-mediated actin nucleation and elongation. Nature Structural & Molecular Biology. 20: 111-8. PMID 23222643 DOI: 10.1038/nsmb.2462  0.635
2012 Taylor JL, White SR, Lauring B, Kull FJ. Crystal structure of the human spastin AAA domain. Journal of Structural Biology. 179: 133-7. PMID 22446388 DOI: 10.1016/J.Jsb.2012.03.002  0.632
2012 Taylor JL, De Silva RS, Kovacikova G, Lin W, Taylor RK, Skorupski K, Kull FJ. The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH. Molecular Microbiology. 83: 457-70. PMID 22053934 DOI: 10.1111/J.1365-2958.2011.07919.X  0.756
2012 Shi W, Taylor RK, Kull FJ. Characterization and Crystallization of BreR, the TetR Family Member Bile Response Repressor of Vibrio Cholerae Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.422  0.452
2012 Day J, Kull FJ, Taylor R. Fatty Acid Regulation of Enteric Infectious Disease Biophysical Journal. 102: 2-7. DOI: 10.1016/J.Bpj.2011.11.1586  0.423
2010 Heuston E, Bronner CE, Kull FJ, Endow SA. A kinesin motor in a force-producing conformation. Bmc Structural Biology. 10: 19. PMID 20602775 DOI: 10.1186/1472-6807-10-19  0.422
2010 Zhao YC, Kull FJ, Cochran JC. Modulation of the kinesin ATPase cycle by neck linker docking and microtubule binding. The Journal of Biological Chemistry. 285: 25213-20. PMID 20558732 DOI: 10.1074/Jbc.M110.123067  0.452
2010 Lowden MJ, Skorupski K, Pellegrini M, Chiorazzo MG, Taylor RK, Kull FJ. Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes. Proceedings of the National Academy of Sciences of the United States of America. 107: 2860-5. PMID 20133655 DOI: 10.1073/Pnas.0915021107  0.456
2010 Thompson ME, Higgs HN, Kull FJ. A Structural and Biochemical Study of the Interaction Between Actin and the Mammalian Formin FRL2 Biophysical Journal. 98: 156a. DOI: 10.1016/J.Bpj.2009.12.837  0.658
2010 Taylor JL, Kull FJ. High Resolution Structural Characterization of the Human Spastin Protein and its Complex With Tubulin Biophysical Journal. 98: 363. DOI: 10.1016/J.Bpj.2009.12.1960  0.609
2009 Cochran JC, Sindelar CV, Mulko NK, Collins KA, Kong SE, Hawley RS, Kull FJ. ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell. 136: 110-22. PMID 19135893 DOI: 10.1016/J.Cell.2008.11.048  0.739
2008 Cochran JC, Kull FJ. Kinesin motors: no strain, no gain. Cell. 134: 918-9. PMID 18805085 DOI: 10.1016/J.Cell.2008.09.005  0.36
2007 De Silva RS, Kovacikova G, Lin W, Taylor RK, Skorupski K, Kull FJ. Crystal structure of the Vibrio cholerae quorum-sensing regulatory protein HapR. Journal of Bacteriology. 189: 5683-91. PMID 17526705 DOI: 10.1128/Jb.01807-06  0.783
2006 Dürrwang U, Fujita-Becker S, Erent M, Kull FJ, Tsiavaliaris G, Geeves MA, Manstein DJ. Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis. Journal of Cell Science. 119: 550-8. PMID 16443752 DOI: 10.1242/Jcs.02774  0.398
2006 Goetz JA, Singh S, Suber LM, Kull FJ, Robbins DJ. A highly conserved amino-terminal region of sonic hedgehog is required for the formation of its freely diffusible multimeric form. The Journal of Biological Chemistry. 281: 4087-93. PMID 16339763 DOI: 10.1074/Jbc.M511427200  0.425
2005 Reubold TF, Eschenburg S, Becker A, Leonard M, Schmid SL, Vallee RB, Kull FJ, Manstein DJ. Crystal structure of the GTPase domain of rat dynamin 1. Proceedings of the National Academy of Sciences of the United States of America. 102: 13093-8. PMID 16141317 DOI: 10.1073/Pnas.0506491102  0.531
2005 De Silva RS, Kovacikova G, Lin W, Taylor RK, Skorupski K, Kull FJ. Crystal structure of the virulence gene activator AphA from Vibrio cholerae reveals it is a novel member of the winged helix transcription factor superfamily. The Journal of Biological Chemistry. 280: 13779-83. PMID 15647287 DOI: 10.1074/Jbc.M413781200  0.773
2004 Kull FJ, Endow SA. A new structural state of myosin. Trends in Biochemical Sciences. 29: 103-6. PMID 15055201 DOI: 10.1016/J.Tibs.2004.01.001  0.477
2003 Holmes KC, Angert I, Kull FJ, Jahn W, Schröder RR. Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide. Nature. 425: 423-7. PMID 14508495 DOI: 10.1038/Nature02005  0.42
2003 Reubold TF, Eschenburg S, Becker A, Kull FJ, Manstein DJ. A structural model for actin-induced nucleotide release in myosin. Nature Structural Biology. 10: 826-30. PMID 14502270 DOI: 10.1038/Nsb987  0.529
2002 Tsiavaliaris G, Fujita-Becker S, Batra R, Levitsky DI, Kull FJ, Geeves MA, Manstein DJ. Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium. Embo Reports. 3: 1099-105. PMID 12393751 DOI: 10.1093/Embo-Reports/Kvf214  0.393
2002 Kollmar M, Dürrwang U, Kliche W, Manstein DJ, Kull FJ. Crystal structure of the motor domain of a class-I myosin. The Embo Journal. 21: 2517-25. PMID 12032065 DOI: 10.1093/Emboj/21.11.2517  0.535
2002 Kull FJ, Endow SA. Kinesin: switch I & II and the motor mechanism. Journal of Cell Science. 115: 15-23. PMID 11801720  0.358
2001 Niemann HH, Knetsch ML, Scherer A, Manstein DJ, Kull FJ. Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms. The Embo Journal. 20: 5813-21. PMID 11689422 DOI: 10.1093/Emboj/20.21.5813  0.551
2001 Kliche W, Fujita-Becker S, Kollmar M, Manstein DJ, Kull FJ. Structure of a genetically engineered molecular motor. The Embo Journal. 20: 40-6. PMID 11226153 DOI: 10.1093/Emboj/20.1.40  0.482
2000 Kull FJ. Motor proteins of the kinesin superfamily: structure and mechanism. Essays in Biochemistry. 35: 61-73. PMID 12471890 DOI: 10.1042/Bse0350061  0.466
1999 Sack S, Kull FJ, Mandelkow E. Motor proteins of the kinesin family. Structures, variations, and nucleotide binding sites. European Journal of Biochemistry / Febs. 262: 1-11. PMID 10231357 DOI: 10.1046/J.1432-1327.1999.00341.X  0.514
1998 Kull FJ, Vale RD, Fletterick RJ. The case for a common ancestor: kinesin and myosin motor proteins and G proteins. Journal of Muscle Research and Cell Motility. 19: 877-86. PMID 10047987 DOI: 10.1023/A:1005489907021  0.666
1998 Kull FJ, Fletterick RJ. Is the tubulin/FtsZ fold related to the G-protein fold? Trends in Cell Biology. 8: 306-7. PMID 9704406 DOI: 10.1016/S0962-8924(98)01319-1  0.502
1996 Sablin EP, Kull FJ, Cooke R, Vale RD, Fletterick RJ. Crystal structure of the motor domain of the kinesin-related motor ncd. Nature. 380: 555-9. PMID 8606780 DOI: 10.1038/380555A0  0.704
1996 Kull FJ, Sablin EP, Lau R, Fletterick RJ, Vale RD. Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature. 380: 550-5. PMID 8606779 DOI: 10.1107/S0108767396090939  0.686
1996 Sablin EP, Kull FJ, Cooke R, Vale RD, Fletterick RJ. Three-dimensional structure of the motor domain of NCD, a kinesin-related motor with reversed polarity of movement Acta Crystallographica Section a Foundations of Crystallography. 52: C211-C211. DOI: 10.1107/S0108767396090927  0.632
1995 Eden D, Luu BQ, Zapata DJ, Sablin EP, Kull FJ. Solution structure of two molecular motor domains: nonclaret disjunctional and kinesin. Biophysical Journal. 68: 59S-64S; discussion . PMID 7787102  0.306
1994 Vale RD, Coppin CM, Malik F, Kull FJ, Milligan RA. Tubulin GTP hydrolysis influences the structure, mechanical properties, and kinesin-driven transport of microtubules. The Journal of Biological Chemistry. 269: 23769-75. PMID 7916345  0.523
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