| Year |
Citation |
Score |
| 2024 |
Lin DY, Kueffer LE, Juneja P, Wales TE, Engen JR, Andreotti AH. Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife. 12. PMID 38189455 DOI: 10.7554/eLife.89489 |
0.573 |
|
| 2023 |
Kueffer LE, Lin DY, Amatya N, Serrenho J, Joseph RE, Courtney AH, Andreotti AH. Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase. Biochemistry. PMID 38091504 DOI: 10.1021/acs.biochem.3c00362 |
0.371 |
|
| 2023 |
Lin DY, Kueffer LE, Juneja P, Wales T, Engen JR, Andreotti AH. Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Biorxiv : the Preprint Server For Biology. PMID 37786675 DOI: 10.1101/2023.06.02.543453 |
0.572 |
|
| 2023 |
Lin DY, Andreotti AH. Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib. Plos One. 18: e0290872. PMID 37651403 DOI: 10.1371/journal.pone.0290872 |
0.355 |
|
| 2022 |
Aryal M, Lin D, Regan K, Du S, Shi H, Alvarado JJ, Ilina TV, Andreotti AH, Smithgall TE. The HIV-1 protein Nef activates the Tec family kinase Btk by stabilizing an intermolecular SH3-SH2 domain interaction. Science Signaling. 15: eabn8359. PMID 36126115 DOI: 10.1126/scisignal.abn8359 |
0.47 |
|
| 2022 |
Brunner C, Betzler AC, Brown JR, Andreotti AH, Grassilli E. Editorial: Targeting Bruton Tyrosine Kinase. Frontiers in Cell and Developmental Biology. 10: 909655. PMID 35557950 DOI: 10.3389/fcell.2022.909655 |
0.326 |
|
| 2022 |
Lowe J, Joseph RE, Andreotti AH. Conformational switches that control the TEC kinase - PLCγ signaling axis. Journal of Structural Biology: X. 6: 100061. PMID 35128378 DOI: 10.1016/j.yjsbx.2022.100061 |
0.319 |
|
| 2021 |
Kueffer LE, Joseph RE, Andreotti AH. Reining in BTK: Interdomain Interactions and Their Importance in the Regulatory Control of BTK. Frontiers in Cell and Developmental Biology. 9: 655489. PMID 34249912 DOI: 10.3389/fcell.2021.655489 |
0.324 |
|
| 2020 |
Joseph RE, Amatya N, Fulton DB, Engen JR, Wales TE, Andreotti A. Differential impact of BTK active site inhibitors on the conformational state of full-length BTK. Elife. 9. PMID 33226337 DOI: 10.7554/eLife.60470 |
0.401 |
|
| 2019 |
Amatya N, Wales TE, Kwon A, Yeung W, Joseph RE, Fulton DB, Kannan N, Engen JR, Andreotti AH. Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases. Proceedings of the National Academy of Sciences of the United States of America. PMID 31591208 DOI: 10.1073/Pnas.1907566116 |
0.659 |
|
| 2019 |
Andersen TCB, Kristiansen PE, Huszenicza Z, Johansson MU, Gopalakrishnan RP, Kjelstrup H, Boyken S, Sundvold-Gjerstad V, Granum S, Sørlie M, Backe PH, Fulton DB, Karlsson BG, Andreotti AH, Spurkland A. The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein. The Journal of Biological Chemistry. PMID 31484725 DOI: 10.1074/Jbc.Ra119.008318 |
0.82 |
|
| 2019 |
Amatya N, Lin DY, Andreotti AH. Dynamic regulatory features of the protein tyrosine kinases. Biochemical Society Transactions. PMID 31395755 DOI: 10.1042/Bst20180590 |
0.49 |
|
| 2018 |
Andreotti AH, Joseph RE, Conley JM, Iwasa J, Berg LJ. Multidomain Control Over TEC Kinase Activation State Tunes the T Cell Response. Annual Review of Immunology. 36: 549-578. PMID 29677469 DOI: 10.1146/Annurev-Immunol-042617-053344 |
0.535 |
|
| 2017 |
Joseph RE, Wales TE, Fulton DB, Engen JR, Andreotti AH. Achieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts. Structure (London, England : 1993). PMID 28867612 DOI: 10.1016/J.Str.2017.07.014 |
0.541 |
|
| 2017 |
Devkota S, Joseph RE, Boyken SE, Fulton DB, Andreotti AH. An autoinhibitory role for the Pleckstrin Homology domain of ITK and its interplay with canonical phospholipid recognition. Biochemistry. PMID 28516764 DOI: 10.1021/Acs.Biochem.6B01182 |
0.811 |
|
| 2016 |
Singh Athwal N, Alagurajan J, Andreotti AH, Hargrove MS. The Role of Reversible Histidine Coordination in Hydroxylamine Reduction by Plant Hemoglobins (Phytoglobins). Biochemistry. PMID 27661977 DOI: 10.1021/Acs.Biochem.6B00775 |
0.323 |
|
| 2016 |
Chopra N, Wales TE, Joseph RE, Boyken SE, Engen JR, Jernigan RL, Andreotti AH. Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases. Plos Computational Biology. 12: e1004826. PMID 27010561 DOI: 10.1371/Journal.Pcbi.1004826 |
0.803 |
|
| 2016 |
Roberts JM, Tarafdar S, Joseph RE, Andreotti AH, Smithgall TE, Engen JR, Wales TE. Dynamics of the Tec-family Tyrosine Kinase SH3 domains. Protein Science : a Publication of the Protein Society. PMID 26808198 DOI: 10.1002/Pro.2887 |
0.592 |
|
| 2015 |
Devkota S, Joseph RE, Min L, Bruce Fulton D, Andreotti AH. Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation. Journal of Molecular Biology. PMID 25916191 DOI: 10.1016/J.Jmb.2015.04.012 |
0.767 |
|
| 2015 |
Korasick DA, Chatterjee S, Tonelli M, Dashti H, Lee SG, Westfall CS, Fulton DB, Andreotti AH, Amarasinghe GK, Strader LC, Jez JM. Defining a two-pronged structural model for PB1 (Phox/Bem1p) domain interaction in plant auxin responses. The Journal of Biological Chemistry. 290: 12868-78. PMID 25839233 DOI: 10.1074/Jbc.M115.648253 |
0.441 |
|
| 2015 |
Xie Q, Fulton DB, Andreotti AH. A selective NMR probe to monitor the conformational transition from inactive to active kinase. Acs Chemical Biology. 10: 262-8. PMID 25248068 DOI: 10.1021/Cb5004702 |
0.579 |
|
| 2014 |
Boyken SE, Chopra N, Xie Q, Joseph RE, Wales TE, Fulton DB, Engen JR, Jernigan RL, Andreotti AH. A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase. Journal of Molecular Biology. 426: 3656-69. PMID 25193673 DOI: 10.1016/J.Jmb.2014.08.018 |
0.834 |
|
| 2014 |
Wang X, Boyken SE, Hu J, Xu X, Rimer RP, Shea MA, Shaw AS, Andreotti AH, Huang YH. Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production. Science Signaling. 7: ra74. PMID 25097034 DOI: 10.1126/Scisignal.2005147 |
0.751 |
|
| 2014 |
Andersen TC, Lindsjø K, Hem CD, Koll L, Kristiansen PE, Skjeldal L, Andreotti AH, Spurkland A. Solubility of recombinant Src homology 2 domains expressed in E. coli can be predicted by TANGO. Bmc Biotechnology. 14: 3. PMID 24423197 DOI: 10.1186/1472-6750-14-3 |
0.459 |
|
| 2013 |
Joseph RE, Kleino I, Wales TE, Xie Q, Fulton DB, Engen JR, Berg LJ, Andreotti AH. Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases. Science Signaling. 6: ra76. PMID 23982207 DOI: 10.1126/Scisignal.2004298 |
0.639 |
|
| 2013 |
Xie Q, Joseph RE, Fulton DB, Andreotti AH. Substrate recognition of PLCγ1 via a specific docking surface on Itk. Journal of Molecular Biology. 425: 683-96. PMID 23219468 DOI: 10.1016/J.Jmb.2012.10.023 |
0.701 |
|
| 2012 |
Boyken SE, Fulton DB, Andreotti AH. Rescue of the aggregation prone Itk Pleckstrin Homology domain by two mutations derived from the related kinases, Btk and Tec. Protein Science : a Publication of the Protein Society. 21: 1288-97. PMID 22761113 DOI: 10.1002/Pro.2114 |
0.802 |
|
| 2012 |
Levytskyy RM, Hirve N, Guimond DM, Min L, Andreotti AH, Tsoukas CD. In Vivo Consequences of Disrupting SH3-Mediated Interactions of the Inducible T-Cell Kinase. Journal of Signal Transduction. 2012: 694386. PMID 22649724 DOI: 10.1155/2012/694386 |
0.696 |
|
| 2012 |
Joseph RE, Ginder ND, Hoy JA, Nix JC, Fulton DB, Honzatko RB, Andreotti AH. Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 145-53. PMID 22297986 DOI: 10.1107/S1744309111049761 |
0.542 |
|
| 2011 |
Joseph RE, Ginder ND, Hoy JA, Nix JC, Honzatko RB, Andreotti AH. Purification, crystallization and preliminary crystallographic analysis of the SH2 domain of IL-2-inducible T-cell kinase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 269-73. PMID 21301103 DOI: 10.1107/S1744309110052346 |
0.515 |
|
| 2011 |
Joseph RE, Andreotti AH. Controlling the activity of the Tec kinase Itk by mutation of the phenylalanine gatekeeper residue. Biochemistry. 50: 221-9. PMID 21138328 DOI: 10.1021/Bi101379M |
0.553 |
|
| 2010 |
Joseph RE, Xie Q, Andreotti AH. Identification of an allosteric signaling network within Tec family kinases. Journal of Molecular Biology. 403: 231-42. PMID 20826165 DOI: 10.1016/J.Jmb.2010.08.035 |
0.692 |
|
| 2010 |
Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harbor Perspectives in Biology. 2: a002287. PMID 20519342 DOI: 10.1101/Cshperspect.A002287 |
0.448 |
|
| 2010 |
Berge T, Sundvold-Gjerstad V, Granum S, Andersen TC, Holthe GB, Claesson-Welsh L, Andreotti AH, Inngjerdingen M, Spurkland A. T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells. Plos One. 5: e9761. PMID 20305788 DOI: 10.1371/Journal.Pone.0009761 |
0.387 |
|
| 2010 |
Min L, Wu W, Joseph RE, Fulton DB, Berg L, Andreotti AH. Disrupting the intermolecular self-association of Itk enhances T cell signaling. Journal of Immunology (Baltimore, Md. : 1950). 184: 4228-35. PMID 20237289 DOI: 10.4049/Jimmunol.0901908 |
0.726 |
|
| 2009 |
Min L, Joseph RE, Fulton DB, Andreotti AH. Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1. Proceedings of the National Academy of Sciences of the United States of America. 106: 21143-8. PMID 19955438 DOI: 10.1073/Pnas.0911309106 |
0.776 |
|
| 2009 |
Joseph RE, Severin A, Min L, Fulton DB, Andreotti AH. SH2-dependent autophosphorylation within the Tec family kinase Itk. Journal of Molecular Biology. 391: 164-77. PMID 19523959 DOI: 10.1016/J.Jmb.2009.06.023 |
0.84 |
|
| 2009 |
Severin A, Joseph RE, Boyken S, Fulton DB, Andreotti AH. Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. Journal of Molecular Biology. 387: 726-43. PMID 19361414 DOI: 10.1016/J.Jmb.2009.02.012 |
0.837 |
|
| 2009 |
Joseph RE, Andreotti AH. Conformational snapshots of Tec kinases during signaling. Immunological Reviews. 228: 74-92. PMID 19290922 DOI: 10.1111/J.1600-065X.2008.00740.X |
0.49 |
|
| 2009 |
Andreotti A, Severin A, Fulton D. Solution Structure of the binary complex between the SH3 and SH2 domain of interleukin-2 tyrosine kinase Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr15912 |
0.776 |
|
| 2008 |
Joseph RE, Andreotti AH. Bacterial expression and purification of interleukin-2 tyrosine kinase: single step separation of the chaperonin impurity. Protein Expression and Purification. 60: 194-7. PMID 18495488 DOI: 10.1016/J.Pep.2008.04.001 |
0.451 |
|
| 2008 |
Severin A, Fulton DB, Andreotti AH. Murine Itk SH3 domain. Journal of Biomolecular Nmr. 40: 285-90. PMID 18320328 DOI: 10.1007/S10858-008-9231-9 |
0.8 |
|
| 2007 |
Joseph RE, Fulton DB, Andreotti AH. Mechanism and functional significance of Itk autophosphorylation. Journal of Molecular Biology. 373: 1281-92. PMID 17897671 DOI: 10.1016/J.Jmb.2007.08.060 |
0.614 |
|
| 2007 |
Joseph RE, Min L, Xu R, Musselman ED, Andreotti AH. A remote substrate docking mechanism for the tec family tyrosine kinases. Biochemistry. 46: 5595-603. PMID 17439160 DOI: 10.1021/Bi700127C |
0.763 |
|
| 2007 |
Joseph RE, Min L, Andreotti AH. The linker between SH2 and kinase domains positively regulates catalysis of the Tec family kinases. Biochemistry. 46: 5455-62. PMID 17425330 DOI: 10.1021/Bi602512E |
0.714 |
|
| 2007 |
Huang YH, Grasis JA, Miller AT, Xu R, Soonthornvacharin S, Andreotti AH, Tsoukas CD, Cooke MP, Sauer K. Positive regulation of Itk PH domain function by soluble IP4. Science (New York, N.Y.). 316: 886-9. PMID 17412921 DOI: 10.1126/Science.1138684 |
0.525 |
|
| 2006 |
Venkitaramani DV, Fulton DB, Andreotti AH, Johansen KM, Johansen J. Mapping the Ca2+ -dependent binding of an invertebrate homolog of protein phosphatase 4 regulatory subunit 2 to the small EF-hand protein, calsensin. Biochimica Et Biophysica Acta. 1763: 322-9. PMID 16600403 DOI: 10.1016/J.Bbamcr.2006.02.013 |
0.38 |
|
| 2006 |
Pletneva EV, Sundd M, Fulton DB, Andreotti AH. Molecular details of Itk activation by prolyl isomerization and phospholigand binding: the NMR structure of the Itk SH2 domain bound to a phosphopeptide. Journal of Molecular Biology. 357: 550-61. PMID 16436281 DOI: 10.1016/J.Jmb.2005.12.073 |
0.78 |
|
| 2006 |
Andreotti AH. Opening the pore hinges on proline. Nature Chemical Biology. 2: 13-4. PMID 16408084 DOI: 10.1038/Nchembio0106-13 |
0.305 |
|
| 2005 |
Venkitaramani DV, Fulton DB, Andreotti AH, Johansen KM, Johansen J. Solution structure and backbone dynamics of Calsensin, an invertebrate neuronal calcium-binding protein. Protein Science : a Publication of the Protein Society. 14: 1894-901. PMID 15937283 DOI: 10.1110/Ps.051412605 |
0.34 |
|
| 2005 |
Min L, Fulton DB, Andreotti AH. A case study of proline isomerization in cell signaling. Frontiers in Bioscience : a Journal and Virtual Library. 10: 385-97. PMID 15574377 DOI: 10.2741/1536 |
0.644 |
|
| 2004 |
Colgan J, Asmal M, Neagu M, Yu B, Schneidkraut J, Lee Y, Sokolskaja E, Andreotti A, Luban J. Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk. Immunity. 21: 189-201. PMID 15308100 DOI: 10.1016/J.Immuni.2004.07.005 |
0.41 |
|
| 2003 |
Breheny PJ, Laederach A, Fulton DB, Andreotti AH. Ligand specificity modulated by prolyl imide bond Cis/Trans isomerization in the Itk SH2 domain: a quantitative NMR study. Journal of the American Chemical Society. 125: 15706-7. PMID 14677936 DOI: 10.1021/Ja0375380 |
0.73 |
|
| 2003 |
Laederach A, Cradic KW, Fulton DB, Andreotti AH. Determinants of intra versus intermolecular self-association within the regulatory domains of Rlk and Itk. Journal of Molecular Biology. 329: 1011-20. PMID 12798690 DOI: 10.1016/S0022-2836(03)00531-X |
0.73 |
|
| 2003 |
Laederach A, Cradic K, Fulton D, Andreotti A. Txk SH3 domain backbone assignments Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5651 |
0.738 |
|
| 2002 |
Mallis RJ, Brazin KN, Fulton DB, Andreotti AH. Structural characterization of a proline-driven conformational switch within the Itk SH2 domain. Nature Structural Biology. 9: 900-5. PMID 12402030 DOI: 10.1038/Nsb864 |
0.84 |
|
| 2002 |
Laederach A, Andreotti AH, Fulton DB. Solution and micelle-bound structures of tachyplesin I and its active aromatic linear derivatives. Biochemistry. 41: 12359-68. PMID 12369825 DOI: 10.1021/Bi026185Z |
0.619 |
|
| 2002 |
Brazin KN, Mallis RJ, Fulton DB, Andreotti AH. Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin A. Proceedings of the National Academy of Sciences of the United States of America. 99: 1899-904. PMID 11830645 DOI: 10.1073/Pnas.042529199 |
0.824 |
|
| 2002 |
Laederach A, Cradic KW, Brazin KN, Zamoon J, Fulton DB, Huang XY, Andreotti AH. Competing modes of self-association in the regulatory domains of Bruton's tyrosine kinase: intramolecular contact versus asymmetric homodimerization. Protein Science : a Publication of the Protein Society. 11: 36-45. PMID 11742120 DOI: 10.1110/Ps.26702 |
0.832 |
|
| 2002 |
Laederach A, Andreotti A, Fulton D. Backbone and 1H assignments for Tachyplesin I, phenylalanine mutant Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5488 |
0.581 |
|
| 2002 |
Laederach A, Andreotti A, Fulton D. Backbone and 1H assignments for Tachyplesin I, tyrosine mutant Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5487 |
0.616 |
|
| 2002 |
Laederach A, Andreotti A, Fulton D. Backbone and 1H assignments for Tachyplesin I, wild type Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5486 |
0.561 |
|
| 2001 |
Watson RM, Woody RW, Lewis RV, Bohle DS, Andreotti AH, Ray B, Miller KW. Conformational changes in pediocin AcH upon vesicle binding and approximation of the membrane-bound structure in detergent micelles. Biochemistry. 40: 14037-46. PMID 11705396 DOI: 10.1021/Bi011031P |
0.365 |
|
| 2000 |
Brazin KN, Fulton DB, Andreotti AH. A specific intermolecular association between the regulatory domains of a Tec family kinase. Journal of Molecular Biology. 302: 607-23. PMID 10986122 DOI: 10.1006/Jmbi.2000.4091 |
0.845 |
|
| 2000 |
Kalben A, Pal S, Andreotti AH, Walker S, Gange D, Biswas K, Kahne D. Calicheamicin-DNA recognition: An analysis of seven different drug-DNA complexes Journal of the American Chemical Society. 122: 8403-8412. DOI: 10.1021/Ja0005183 |
0.529 |
|
| 1998 |
Kapoor TM, Andreotti AH, Schreiber SL. Exploring the specificity pockets of two homologous SH3 domain using structure-based, split-pool synthesis and affinity-based selection Journal of the American Chemical Society. 120: 23-29. DOI: 10.1021/ja972728u |
0.689 |
|
| 1997 |
Andreotti AH, Bunnell SC, Feng S, Berg LJ, Schreiber SL. Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature. 385: 93-7. PMID 8985255 DOI: 10.1038/385093A0 |
0.697 |
|
| 1995 |
Liang R, Andreotti AH, Kahne D. Sensitivity Of Glycopeptide Conformation To Carbohydrate Chain Length Journal of the American Chemical Society. 117: 10395-10396. DOI: 10.1021/Ja00146A030 |
0.51 |
|
| 1994 |
Walker SL, Andreotti AH, Kahne DE. NMR characterization of calicheamicin γ1 I bound to DNA Tetrahedron. 50: 1351-1360. DOI: 10.1016/S0040-4020(01)80623-2 |
0.472 |
|
| 1993 |
Andreotti AH, Kahne D. The effects of glycosylation on peptide backbone conformation Journal of the American Chemical Society. 115: 3352-3353. DOI: 10.1021/Ja00061A053 |
0.513 |
|
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