Horst C. Kessler - Publications

Affiliations: 
Chemistry Technical University of Munich (TUM), München, Bayern, Germany 
Area:
Synthesis and structure of peptides
Website:
http://www.org.chemie.tu-muenchen.de/akkessler/index.php?option=com_content&view=article&id=17&Itemid=46&lang=en

301 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Laukien FH, Banci L, Meier BH, Kessler H, Griesinger C. Tony W. Keller (1937-2023). Angewandte Chemie (International Ed. in English). e202316747. PMID 37997554 DOI: 10.1002/anie.202316747  0.382
2019 Reichart F, Maltsev OV, Kapp TG, Räder AFB, Weinmüller M, Marelli UK, Notni J, Wurzer A, Beck R, Wester HJ, Steiger K, Di Maro S, Di Leva FS, Marinelli L, Nieberler M, ... ... Kessler H, et al. Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide. Journal of Medicinal Chemistry. PMID 30657681 DOI: 10.1021/Acs.Jmedchem.8B01588  0.312
2018 Räder AFB, Weinmüller M, Reichart F, Schumacher-Klinger A, Merzbach S, Gilon C, Hoffman A, Kessler H. Orally active peptides - is there a magic bullet? Angewandte Chemie (International Ed. in English). PMID 30144240 DOI: 10.1002/Anie.201807298  0.314
2018 Schumacher-Klinger A, Fanous J, Merzbach S, Weinmueller M, Reichart F, Räder AFB, Gitlin-Domaglaska A, Gilon C, Kessler H, Hoffman A. Enhancing oral bioavailability of cyclic RGD hexa-peptides by the Lipophilic Prodrug Charge Masking approach: Redirection of peptide intestinal permeability from paracellular to transcellular pathway. Molecular Pharmaceutics. PMID 29976060 DOI: 10.1021/Acs.Molpharmaceut.8B00466  0.325
2018 Di Leva FS, Tomassi S, Di Maro S, Reichart F, Notni J, Dangi A, Marelli UK, Brancaccio D, Merlino F, Wester HJ, Novellino E, Kessler H, Marinelli L. From a Helix to a Small Cycle: Metadynamics-Inspired αvβ6 Integrin Selective Ligands. Angewandte Chemie (International Ed. in English). PMID 29660806 DOI: 10.1002/Anie.201803250  0.312
2018 Durek T, Cromm PM, White AM, Schroeder CI, Kaas Q, Weidmann J, Ahmad Fuaad A, Cheneval O, Harvey PJ, Daly NL, Zhou Y, Dellsén A, Österlund T, Larsson N, Knerr L, ... ... Kessler H, et al. Development of novel melanocortin receptor agonists based on the cyclic peptide framework of sunflower trypsin inhibitor-1. Journal of Medicinal Chemistry. PMID 29605997 DOI: 10.1021/Acs.Jmedchem.8B00170  0.34
2018 Kapp TG, Di Leva FS, Notni J, Räder AFB, Fottner M, Reichart F, Reich D, Wurzer A, Steiger K, Novellino E, Marelli UK, Wester HJ, Marinelli L, Kessler H. N-methylation of isoDGR Peptides: Discovery of a Selective α5β1-Integrin Ligand as a Potent Tumor Imaging Agent. Journal of Medicinal Chemistry. PMID 29489355 DOI: 10.1021/Acs.Jmedchem.7B01752  0.334
2017 Kessler H, Weinmüller M, Rechenmacher F, Kiran Marelli U, Reichart F, Kapp TG, Räder AB, Di Leva FS, Marinelli L, Novellino E, Muñoz Félix JM, Hodivala-Dilke K, Schumacher A, Fanous J, Gilon C, et al. Overcoming the lack of oral availability of cyclic hexapeptides: Design of a new selective and orally available ligand for the integrin αvβ3. Angewandte Chemie (International Ed. in English). PMID 29072809 DOI: 10.1002/Anie.201709709  0.316
2017 Räder AFB, Reichart F, Weinmüller M, Kessler H. Improving oral bioavailability of cyclic peptides by N-methylation. Bioorganic & Medicinal Chemistry. PMID 28886995 DOI: 10.1016/J.Bmc.2017.08.031  0.33
2017 Cai M, Marelli UK, Mertz B, Beck JG, Opperer F, Rechenmacher F, Kessler H, Hruby VJ. Structural Insights into Selective Ligand-Receptor Interactions Leading to Receptor Inactivation Utilizing Selective Melanocortin 3 Receptor Antagonists. Biochemistry. PMID 28715181 DOI: 10.1021/Acs.Biochem.7B00407  0.358
2015 Maltsev OV, Marelli UK, Kapp TG, Di Leva FS, Di Maro S, Nieberler M, Reuning U, Schwaiger M, Novellino E, Marinelli L, Kessler H. Stable Peptides Instead of Stapled Peptides: Highly Potent αvβ6-Selective Integrin Ligands. Angewandte Chemie (International Ed. in English). PMID 26663660 DOI: 10.1002/Anie.201508709  0.328
2015 Marelli UK, Ovadia O, Frank AO, Chatterjee J, Gilon C, Hoffman A, Kessler H. cis-Peptide Bonds: A Key for Intestinal Permeability of Peptides? . Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 15148-52. PMID 26337831 DOI: 10.1002/Chem.201501600  0.352
2015 Cai M, Marelli UK, Bao J, Beck JG, Opperer F, Rechenmacher F, McLeod KR, Zingsheim MR, Doedens L, Kessler H, Hruby VJ. Systematic Backbone Conformational Constraints on a Cyclic Melanotropin Ligand Leads to Highly Selective Ligands for Multiple Melanocortin Receptors. Journal of Medicinal Chemistry. 58: 6359-67. PMID 26218460 DOI: 10.1021/Acs.Jmedchem.5B00102  0.324
2015 Marelli UK, Bezençon J, Puig E, Ernst B, Kessler H. Enantiomeric cyclic peptides with different Caco-2 permeability suggest carrier-mediated transport. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 8023-7. PMID 25917866 DOI: 10.1002/Chem.201501270  0.322
2015 Frank AO, Freudenberger JC, Shaytan AK, Kessler H, Luy B. Direct prediction of residual dipolar couplings of small molecules in a stretched gel by stochastic molecular dynamics simulations. Magnetic Resonance in Chemistry : Mrc. 53: 213-7. PMID 25612077 DOI: 10.1002/Mrc.4181  0.309
2014 Pallarola D, Bochen A, Boehm H, Rechenmacher F, Sobahi TR, Spatz JP, Kessler H. Interface Immobilization Chemistry of cRGD-based Peptides Regulates Integrin Mediated Cell Adhesion. Advanced Functional Materials. 24: 943-956. PMID 25810710 DOI: 10.1002/Adfm.201302411  0.32
2014 Marelli UK, Frank AO, Wahl B, La Pietra V, Novellino E, Marinelli L, Herdtweck E, Groll M, Kessler H. Receptor-bound conformation of cilengitide better represented by its solution-state structure than the solid-state structure. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 14201-6. PMID 25251673 DOI: 10.1002/Chem.201403839  0.337
2014 Hegemann JD, De Simone M, Zimmermann M, Knappe TA, Xie X, Di Leva FS, Marinelli L, Novellino E, Zahler S, Kessler H, Marahiel MA. Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. Journal of Medicinal Chemistry. 57: 5829-34. PMID 24949551 DOI: 10.1021/Jm5004478  0.32
2014 Conibear AC, Bochen A, Rosengren KJ, Stupar P, Wang C, Kessler H, Craik DJ. The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: A proof-of-concept study using the integrin-binding RGD motif. Chembiochem : a European Journal of Chemical Biology. 15: 451-9. PMID 24382674 DOI: 10.1002/Cbic.201300568  0.339
2013 Å imeček J, Hermann P, Havlíčková J, Herdtweck E, Kapp TG, Engelbogen N, Kessler H, Wester HJ, Notni J. A cyclen-based tetraphosphinate chelator for the preparation of radiolabeled tetrameric bioconjugates. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 7748-57. PMID 23613345 DOI: 10.1002/Chem.201300338  0.324
2013 Bochen A, Marelli UK, Otto E, Pallarola D, Mas-Moruno C, Di Leva FS, Boehm H, Spatz JP, Novellino E, Kessler H, Marinelli L. Biselectivity of isoDGR peptides for fibronectin binding integrin subtypes α5β1 and αvβ6: conformational control through flanking amino acids. Journal of Medicinal Chemistry. 56: 1509-19. PMID 23362923 DOI: 10.1021/Jm301221X  0.358
2013 Shen Y, Schottelius M, Zelenka K, De Simone M, Pohle K, Kessler H, Wester HJ, Schmutz P, Alberto R. Orthogonally protected artificial amino acid as tripod ligand for automated peptide synthesis and labeling with [99mTc(OH2) 3(CO)3]+ Bioconjugate Chemistry. 24: 26-35. PMID 23237229 DOI: 10.1021/Bc3003327  0.334
2013 Chatterjee J, Rechenmacher F, Kessler H. N-methylation of peptides and proteins: an important element for modulating biological functions. Angewandte Chemie (International Ed. in English). 52: 254-69. PMID 23161799 DOI: 10.1002/Anie.201205674  0.317
2013 Weigelt S, Huber T, Hofmann F, Jost M, Ritzefeld M, Luy B, Freudenberger C, Majer Z, Vass E, Greie J, Panella L, Kaptein B, Broxterman QB, Kessler H, Altendorf K, et al. Corrigendum: Synthesis and Conformational Analysis of Efrapeptins Chemistry - a European Journal. 19: 3264-3264. DOI: 10.1002/Chem.201300488  0.307
2012 Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, ... ... Kessler H, et al. In support of the BMRB. Nature Structural & Molecular Biology. 19: 854-60. PMID 22955930 DOI: 10.1038/Nsmb.2371  0.599
2012 Beck JG, Chatterjee J, Laufer B, Kiran MU, Frank AO, Neubauer S, Ovadia O, Greenberg S, Gilon C, Hoffman A, Kessler H. Intestinal permeability of cyclic peptides: common key backbone motifs identified. Journal of the American Chemical Society. 134: 12125-33. PMID 22737969 DOI: 10.1021/Ja303200D  0.359
2012 Spiegel J, Mas-Moruno C, Kessler H, Lubell WD. Cyclic aza-peptide integrin ligand synthesis and biological activity. The Journal of Organic Chemistry. 77: 5271-8. PMID 22582818 DOI: 10.1021/Jo300311Q  0.359
2012 Martin I, Dohmen C, Mas-Moruno C, Troiber C, Kos P, Schaffert D, Lächelt U, Teixidó M, Günther M, Kessler H, Giralt E, Wagner E. Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery. Organic & Biomolecular Chemistry. 10: 3258-68. PMID 22407126 DOI: 10.1039/C2Ob06907E  0.31
2012 Chatterjee J, Laufer B, Kessler H. Synthesis of N-methylated cyclic peptides. Nature Protocols. 7: 432-44. PMID 22322216 DOI: 10.1038/Nprot.2011.450  0.336
2012 Joner M, Cheng Q, Schönhofer-Merl S, Lopez M, Neubauer S, Mas-Moruno C, Laufer B, Kolodgie FD, Kessler H, Virmani R. Polymer-free immobilization of a cyclic RGD peptide on a nitinol stent promotes integrin-dependent endothelial coverage of strut surfaces. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 100: 637-45. PMID 22278946 DOI: 10.1002/Jbm.B.31988  0.301
2012 Weigelt S, Huber T, Hofmann F, Jost M, Ritzefeld M, Luy B, Freudenberger C, Majer Z, Vass E, Greie JC, Panella L, Kaptein B, Broxterman QB, Kessler H, Altendorf K, et al. Synthesis and conformational analysis of efrapeptins. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 478-87. PMID 22147615 DOI: 10.1002/Chem.201102134  0.373
2011 Chatterjee J, Laufer B, Beck JG, Helyes Z, Pintér E, Szolcsányi J, Horvath A, Mandl J, Reubi JC, Kéri G, Kessler H. N-Methylated sst2 Selective Somatostatin Cyclic Peptide Analogue as a Potent Candidate for Treating Neurogenic Inflammation. Acs Medicinal Chemistry Letters. 2: 509-14. PMID 24900340 DOI: 10.1021/Ml200032V  0.334
2011 Demmer O, Dijkgraaf I, Schumacher U, Marinelli L, Cosconati S, Gourni E, Wester HJ, Kessler H. Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4 Journal of Medicinal Chemistry. 54: 7648-7662. PMID 21905730 DOI: 10.1021/Jm2009716  0.317
2011 Knappe TA, Manzenrieder F, Mas-Moruno C, Linne U, Sasse F, Kessler H, Xie X, Marahiel MA. Introducing Lasso Peptides as Molecular Scaffolds for Drug Design: Engineering of an Integrin Antagonist Angewandte Chemie. 50: 8714-8717. PMID 21812076 DOI: 10.1002/Anie.201102190  0.325
2011 Ovadia O, Greenberg S, Chatterjee J, Laufer B, Opperer F, Kessler H, Gilon C, Hoffman A. The effect of multiple N-methylation on intestinal permeability of cyclic hexapeptides. Molecular Pharmaceutics. 8: 479-87. PMID 21375270 DOI: 10.1021/Mp1003306  0.315
2010 Mas-Moruno C, Rechenmacher F, Kessler H. Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation Anti-Cancer Agents in Medicinal Chemistry. 10: 753-768. PMID 21269250 DOI: 10.2174/187152010794728639  0.313
2010 Fiedler J, Groll J, Engelhardt E, Gasteier P, Dahmen C, Kessler H, Moeller M, Brenner RE. NCO-sP(EO-stat-PO) surface coatings preserve biochemical properties of RGD peptides. International Journal of Molecular Medicine. 27: 139-145. PMID 21069259 DOI: 10.3892/Ijmm.2010.553  0.309
2010 Frank AO, Otto E, Mas-Moruno C, Schiller HB, Marinelli L, Cosconati S, Bochen A, Vossmeyer D, Zahn G, Stragies R, Novellino E, Kessler H. Conformational control of integrin-subtype selectivity in isoDGR peptide motifs: a biological switch. Angewandte Chemie (International Ed. in English). 49: 9278-81. PMID 20957712 DOI: 10.1002/Anie.201004363  0.328
2010 Doedens L, Opperer F, Cai M, Beck JG, Dedek M, Palmer E, Hruby VJ, Kessler H. Multiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity: pharmacological and conformational studies. Journal of the American Chemical Society. 132: 8115-28. PMID 20496895 DOI: 10.1021/Ja101428M  0.334
2009 Kessler H, Chatterjee J, Doedens L, Operrer F, Biron E, Hoyer D, Schmid H, Gilon C, Hruby VJ, Mierkes DF. New perspective in peptide chemistry by N-alkylation. Advances in Experimental Medicine and Biology. 611: 229-31. PMID 19400173 DOI: 10.1007/978-0-387-73657-0_106  0.313
2009 Laufer B, Chatterjee J, Frank AO, Kessler H. Making double-minded peptides strong-willed? The side chain impact on the backbone conformation of N-methylated cyclic pentapeptides. Advances in Experimental Medicine and Biology. 611: 157-8. PMID 19400138 DOI: 10.1007/978-0-387-73657-0_71  0.342
2009 Chatterjee J, Ovadia O, Gilon C, Hoffman A, Mierke D, Kessler H. N-methylated cyclic pentapeptides as template structures. Advances in Experimental Medicine and Biology. 611: 109-10. PMID 19400115 DOI: 10.1007/978-0-387-73657-0_48  0.526
2009 Pandya MJ, Bendz H, Manzenrieder F, Noessner E, Kessler H, Buchner J, Issels RD. Interaction of human heat shock protein 70 with tumor-associated peptides. Biological Chemistry. 390: 305-12. PMID 19199830 DOI: 10.1515/Bc.2009.038  0.302
2009 Altmann KH, Buchner J, Kessler H, Diederich F, Kräutler B, Lippard S, Liskamp R, Müller K, Nolan EM, Samori B, Schneider G, Schreiber SL, Schwalbe H, Toniolo C, van Boeckel CA, et al. The state of the art of chemical biology. Chembiochem : a European Journal of Chemical Biology. 10: 16-29. PMID 19115274 DOI: 10.1002/cbic.200800758  0.331
2009 Laufer B, Chatterjee J, Frank AO, Kessler H. Can N-methylated amino acids serve as substitutes for prolines in conformational design of cyclic pentapeptides? Journal of Peptide Science : An Official Publication of the European Peptide Society. 15: 141-6. PMID 18985637 DOI: 10.1002/Psc.1076  0.354
2009 Koppitz M, Spellig T, Kahmann R, Kessler H. Lipoconjugates: structure-activity studies for pheromone analogues of Ustilago maydis with varied lipophilicity. International Journal of Peptide and Protein Research. 48: 377-390. PMID 8919059 DOI: 10.1111/J.1399-3011.1996.Tb00855.X  0.348
2009 Gerz M, Matter H, Kessler H. Synthesis and solution structure of an S-glycosylated cyclic hexapeptide. Evidence for conformational change induced by glycosylation. International Journal of Peptide and Protein Research. 43: 248-257. PMID 8005747 DOI: 10.1111/J.1399-3011.1994.Tb00387.X  0.321
2009 Matter H, Gemmecker G, Kessler H. Influence of serine in position i on conformation and dynamics of reverse turns. International Journal of Peptide and Protein Research. 45: 430-440. PMID 7591482 DOI: 10.1111/J.1399-3011.1995.Tb01058.X  0.362
2009 Kessler H, Haupt A, Schudok M, Ziegler K, Frimmer M. Peptide conformations--49(1): synthesis and structure-activity relationships of side chain modified peptides of cyclo(-D-Pro-Phe-Thr-Lys-Trp-Phe.). International Journal of Peptide and Protein Research. 32: 183-193. PMID 2907513 DOI: 10.1111/J.1399-3011.1988.Tb00933.X  0.366
2009 Kessler H, Haupt A, Frimmer M, Ziegler K. Synthesis of a cyclic retro analogue of somatostatin suitable for photoaffinity labelling. International Journal of Peptide and Protein Research. 29: 621-628. PMID 2886443 DOI: 10.1111/J.1399-3011.1987.Tb02292.X  0.342
2009 Kessler H, Geyer A, Matter H, Kock M. Unusual thionation of a cyclic hexapeptide. Conformational changes and dynamics. International Journal of Peptide and Protein Research. 40: 25-40. PMID 1428538 DOI: 10.1111/J.1399-3011.1992.Tb00101.X  0.364
2009 Kessler H, Matter H, Gemmecker G, Diehl H-, Isernia C, Mronga S. The pseudo-βI-turn : a new structural motif with a cis peptide bond in cyclic hexapeptides International Journal of Peptide and Protein Research. 43: 47-61. DOI: 10.1111/J.1399-3011.1994.Tb00375.X  0.368
2009 Kessler H, Klein M, Wagner K. Peptide conformation. 48. Conformation and biological activity of proline containing cyclic retro-analogues of somatostatin. International Journal of Peptide and Protein Research. 31: 481-498. DOI: 10.1111/J.1399-3011.1988.Tb00907.X  0.39
2009 Kessler H, Hölzemann G, Zechel C. Peptide conformations. 33. Conformational analysis of cyclic enkephalin analogs of the type Tyr‐cyclo‐(‐N ω ‐Xxx‐Gly‐Phe‐Leu‐)* International Journal of Peptide and Protein Research. 25: 267-279. DOI: 10.1111/J.1399-3011.1985.Tb02174.X  0.403
2008 Pellecchia M, Bertini I, Cowburn D, Dalvit C, Giralt E, Jahnke W, James TL, Homans SW, Kessler H, Luchinat C, Meyer B, Oschkinat H, Peng J, Schwalbe H, Siegal G. Perspectives on NMR in drug discovery: a technique comes of age. Nature Reviews. Drug Discovery. 7: 738-45. PMID 19172689 DOI: 10.1038/Nrd2606  0.595
2008 Kummerlöwe G, Knör S, Frank AO, Paululat T, Kessler H, Luy B. Deuterated polymer gels for measuring anisotropic NMR parameters with strongly reduced artefacts. Chemical Communications (Cambridge, England). 5722-4. PMID 19009060 DOI: 10.1039/B812905C  0.308
2008 Klages J, Kotzsch A, Coles M, Sebald W, Nickel J, Müller T, Kessler H. The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding. Biochemistry. 47: 11930-9. PMID 18937504 DOI: 10.1021/Bi801059J  0.306
2008 Chatterjee J, Gilon C, Hoffman A, Kessler H. N-methylation of peptides: a new perspective in medicinal chemistry. Accounts of Chemical Research. 41: 1331-42. PMID 18636716 DOI: 10.1021/Ar8000603  0.329
2008 Hirschfeld-Warneken VC, Arnold M, Cavalcanti-Adam A, López-García M, Kessler H, Spatz JP. Cell adhesion and polarisation on molecularly defined spacing gradient surfaces of cyclic RGDfK peptide patches. European Journal of Cell Biology. 87: 743-50. PMID 18572273 DOI: 10.1016/J.Ejcb.2008.03.011  0.308
2008 Kalinina S, Gliemann H, López-García M, Petershans A, Auernheimer J, Schimmel T, Bruns M, Schambony A, Kessler H, Wedlich D. Isothiocyanate-functionalized RGD peptides for tailoring cell-adhesive surface patterns. Biomaterials. 29: 3004-13. PMID 18433862 DOI: 10.1016/J.Biomaterials.2008.04.003  0.332
2008 Demmer O, Dijkgraaf I, Schottelius M, Wester H-, Kessler H. Introduction of functional groups into peptides via N-alkylation. Organic Letters. 10: 2015-2018. PMID 18407647 DOI: 10.1021/Ol800654N  0.324
2008 Kaufmann D, Fiedler A, Junger A, Auernheimer J, Kessler H, Weberskirch R. Chemical conjugation of linear and cyclic RGD moieties to a recombinant elastin-mimetic polypeptide--a versatile approach towards bioactive protein hydrogels. Macromolecular Bioscience. 8: 577-88. PMID 18350537 DOI: 10.1002/Mabi.200700234  0.344
2008 Chatterjee J, Mierke DF, Kessler H. Conformational preference and potential templates of N-methylated cyclic pentaalanine peptides. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 1508-17. PMID 18080261 DOI: 10.1002/Chem.200701029  0.6
2007 Heckmann D, Kessler H. Design and chemical synthesis of integrin ligands. Methods in Enzymology. 426: 463-503. PMID 17697896 DOI: 10.1016/S0076-6879(07)26020-3  0.325
2007 Furrer J, John M, Kessler H, Luy B. J-Spectroscopy in the presence of residual dipolar couplings: determination of one-bond coupling constants and scalable resolution. Journal of Biomolecular Nmr. 37: 231-43. PMID 17235497 DOI: 10.1007/S10858-006-9130-X  0.369
2007 Lössner D, Kessler H, Thumshirn G, Dahmen C, Wiltschi B, Tanaka M, Knoll W, Sinner EK, Reuning U. Binding of small mono- and oligomeric integrin ligands to membrane-embedded integrins monitored by surface plasmon-enhanced fluorescence spectroscopy. Analytical Chemistry. 78: 4524-33. PMID 16808462 DOI: 10.1021/Ac052078+  0.303
2006 Chatterjee J, Mierke D, Kessler H. N-methylated cyclic pentaalanine peptides as template structures Journal of the American Chemical Society. 128: 15164-15172. PMID 17117868 DOI: 10.1021/Ja063123D  0.604
2006 Heller M, Sukopp M, Tsomaia N, John M, Mierke DF, Reif B, Kessler H. The conformation of cyclo(-D-Pro-Ala4-) as a model for cyclic pentapeptides of the DL4 type. Journal of the American Chemical Society. 128: 13806-14. PMID 17044709 DOI: 10.1021/Ja063174A  0.716
2006 Biron E, Chatterjee J, Kessler H. Solid-phase synthesis of 1,3-azole-based peptides and peptidomimetics. Organic Letters. 8: 2417-20. PMID 16706540 DOI: 10.1021/Ol0607645  0.313
2006 John M, Wendeler M, Heller M, Sandhoff K, Kessler H. Characterization of human saposins by NMR spectroscopy. Biochemistry. 45: 5206-16. PMID 16618109 DOI: 10.1021/bi051944  0.345
2006 Cavalcanti-Adam EA, Micoulet A, Blümmel J, Auernheimer J, Kessler H, Spatz JP. Lateral spacing of integrin ligands influences cell spreading and focal adhesion assembly European Journal of Cell Biology. 85: 219-224. PMID 16546564 DOI: 10.1016/J.Ejcb.2005.09.011  0.301
2006 Biron E, Chatterjee J, Kessler H. Optimized selective N-methylation of peptides on solid support. Journal of Peptide Science : An Official Publication of the European Peptide Society. 12: 213-9. PMID 16189816 DOI: 10.1002/Psc.711  0.315
2006 Kessler H, Biron E, Chatterjee J. Solid-Phase Synthesis of 1,3-Azole-Based Peptides Synfacts. 2006: 0861-0861. DOI: 10.1055/S-2006-941989  0.3
2006 Auernheimer J, Haubner R, Schottelius M, Wester H, Kessler H. Radio-analytical determination of the coating efficiency of cyclic RGD peptides Helvetica Chimica Acta. 89: 833-840. DOI: 10.1002/Hlca.200690085  0.315
2006 Kessler H. Konformation und biologische Wirkung von cyclischen Peptiden Angewandte Chemie. 94: 509-520. DOI: 10.1002/Ange.19820940705  0.327
2005 Auernheimer J, Dahmen C, Hersel U, Bausch aA, Kessler H. Photoswitched cell adhesion on surfaces with RGD peptides. Journal of the American Chemical Society. 127: 16107-16110. PMID 16287297 DOI: 10.1021/Ja053648Q  0.31
2005 Klages J, Neubauer C, Coles M, Kessler H, Luy B. Structure refinement of cyclosporin A in chloroform by using RDCs measured in a stretched PDMS-gel. Chembiochem : a European Journal of Chemical Biology. 6: 1672-8. PMID 16138307 DOI: 10.1002/Cbic.200500146  0.314
2005 Dehner A, Kessler H. Diffusion NMR Spectroscopy: Folding and Aggregation of Domains in p53 Chembiochem. 6: 1550-1565. PMID 16138303 DOI: 10.1002/Cbic.200500093  0.315
2005 Biron E, Kessler H. Convenient synthesis of N-methylamino acids compatible with Fmoc solid-phase peptide synthesis. The Journal of Organic Chemistry. 70: 5183-9. PMID 15960522 DOI: 10.1021/Jo050477Z  0.308
2005 Luy B, Kobzar K, Knör S, Furrer J, Heckmann D, Kessler H. Orientational properties of stretched polystyrene gels in organic solvents and the suppression of their residual 1H NMR signals. Journal of the American Chemical Society. 127: 6459-65. PMID 15853354 DOI: 10.1021/Ja043344O  0.319
2005 Deshmukh MV, Voll G, Kühlewein A, Mäcke H, Schmitt J, Kessler H, Gemmecker G. NMR studies reveal structural differences between the gallium and yttrium complexes of DOTA-D-Phe1-Tyr3-octreotide. Journal of Medicinal Chemistry. 48: 1506-14. PMID 15743193 DOI: 10.1021/Jm0496335  0.363
2005 Schwalbe H, Stilz HU, Kessler H. Editorial: NMR Spectroscopy of Biomacromolecules in Drug Discovery and Beyond Chembiochem. 6: 1475-1478. DOI: 10.1002/Cbic.200590029  0.459
2004 Kühlewein A, Voll G, Alvarez BH, Kessler H, Fischer G, Rahfeld J, Gemmecker G. Solution structure of Escherichia coli Par10: The prototypic member of the Parvulin family of peptidyl‐prolyl cis/trans isomerases Protein Science. 13: 2378-2387. PMID 15322281 DOI: 10.1110/Ps.04756704  0.339
2004 Marinelli L, Gottschalk KE, Meyer A, Novellino E, Kessler H. Human integrin alphavbeta5: homology modeling and ligand binding. Journal of Medicinal Chemistry. 47: 4166-77. PMID 15293989 DOI: 10.1021/Jm030635J  0.309
2004 Riemer C, Bayer T, Schmitt H, Kessler H. 3-Azido-aspartic acid derivatives - Orthogonally protected precursors for the stereoselective incorporation of 2,3-diaminosuccinic acid into peptide structures Journal of Peptide Research. 63: 196-199. PMID 15049830 DOI: 10.1111/J.1399-3011.2003.00117.X  0.31
2004 Haubner R, Bruchertseifer F, Bock M, Kessler H, Schwaiger M, Wester H-. Synthesis and biological evaluation of a 99mTc-labelled cyclic RGD peptide for imaging the αvβ3 expression Nuklearmedizin-Nuclear Medicine. 43: 26-32. DOI: 10.1055/S-0038-1623911  0.302
2003 Locardi E, Boer J, Modlinger A, Schuster A, Holzmann B, Kessler H. Synthesis and Structure−Activity Relationship of Mannose-Based Peptidomimetics Selectively Blocking Integrin α4β7 Binding to Mucosal Addressin Cell Adhesion Molecule-1 Journal of Medicinal Chemistry. 46: 5752-5762. PMID 14667228 DOI: 10.1021/Jm020487H  0.323
2003 Dehner A, Furrer J, Richter K, Schuster I, Buchner J, Kessler H. NMR chemical shift perturbation study of the N-terminal domain of Hsp90 upon binding of ADP, AMP-PNP, geldanamycin, and radicicol. Chembiochem. 4: 870-877. PMID 12964162 DOI: 10.1002/Cbic.200300658  0.315
2003 van Well RM, Marinelli L, Altona C, Erkelens K, Siegal G, van Raaij M, Llamas-Saiz AL, Kessler H, Novellino E, Lavecchia A, van Boom JH, Overhand M. Conformational analysis of furanoid epsilon-sugar amino acid containing cyclic peptides by NMR spectroscopy, molecular dynamics simulation, and X-ray crystallography: evidence for a novel turn structure. Journal of the American Chemical Society. 125: 10822-9. PMID 12952461 DOI: 10.1021/JA035461+  0.393
2003 Guthaus E, Schmiedeberg N, Bürgle M, Magdolen V, Kessler H, Schmitt M. The urokinase receptor (uPAR, CD87) as a target for tumor therapy: uPA-silica particles (SP-uPA) as a new tool for assessing synthetic peptides to interfere with uPA/uPA-receptor interaction. Recent Results in Cancer Research. 162: 3-14. PMID 12790317 DOI: 10.1007/978-3-642-59349-9_1  0.301
2003 Thumshirn G, Hersel U, Goodman SL, Kessler H. Multimeric cyclic RGD peptides as potential tools for tumor targeting: Solid-phase peptide synthesis and chemoselective oxime ligation Chemistry - a European Journal. 9: 2717-2725. PMID 12772286 DOI: 10.1002/Chem.200204304  0.312
2003 Weber D, Berger C, Eickelmann P, Antel J, Kessler H. Design of selective peptidomimetic agonists for the human orphan receptor BRS-3. Journal of Medicinal Chemistry. 46: 1918-1930. PMID 12723954 DOI: 10.1021/Jm0210921  0.33
2003 Schwalbe H, Kessler H. 900-MHz-NMR-Spektrometer in München und Frankfurt Nachrichten Aus Der Chemie. 51: 412-417. DOI: 10.1002/Nadc.20030510406  0.508
2003 Van Well RM, Marinelli L, Erkelens K, Van der Marel GA, Lavecchia A, Overkleeft HS, Va Boom JH, Kessler H, Overhand M. Synthesis and structural analysis of cyclic oligomers consisting of furanoid and pyranoid ε-sugar amino acids European Journal of Organic Chemistry. 2303-2313. DOI: 10.1002/Ejoc.200300031  0.351
2002 Schmiedeberg N, Schmitt M, Rölz C, Truffault V, Sukopp M, Bürgle M, Wilhelm OG, Schmalix W, Magdolen V, Kessler H. Synthesis, Solution Structure, and Biological Evaluation of Urokinase Type Plasminogen Activator (uPA)-Derived Receptor Binding Domain Mimetics Journal of Medicinal Chemistry. 45: 4984-4994. PMID 12408709 DOI: 10.1021/Jm020254Q  0.318
2002 Gottschling D, Boer J, Marinelli L, Voll G, Haupt M, Schuster A, Holzmann B, Kessler H. Synthesis and NMR structure of peptidomimetic alpha4beta7-integrin antagonists. Chembiochem : a European Journal of Chemical Biology. 3: 575-8. PMID 12325015 DOI: 10.1002/1439-7633(20020603)3:6<575::Aid-Cbic575>3.0.Co;2-7  0.326
2002 Sato S, Kopitz C, Schmalix WA, Muehlenweg B, Kessler H, Schmitt M, Krüger A, Magdolen V. High-affinity urokinase-derived cyclic peptides inhibiting urokinase/urokinase receptor-interaction: effects on tumor growth and spread Febs Letters. 528: 212-216. PMID 12297307 DOI: 10.1016/S0014-5793(02)03311-2  0.325
2002 Weber D, Berger C, Heinrich T, Eickelmann P, Antel J, Kessler H. Systematic optimization of a lead-structure identities for a selective short peptide agonist for the human orphan receptor BRS-3. Journal of Peptide Science. 8: 461-475. PMID 12212809 DOI: 10.1002/Psc.407  0.364
2002 Gottschling D, Boer J, Schuster A, Holzmann B, Kessler H. Combinatorial and Rational Strategies To Develop Nonpeptidic α4β7‐Integrin Antagonists from Cyclic Peptides Angewandte Chemie. 41: 3007-3011. PMID 12203440 DOI: 10.1002/1521-3773(20020816)41:16<3007::Aid-Anie3007>3.0.Co;2-3  0.31
2002 Stöckle M, Voll G, Günther R, Lohof E, Locardi E, Gruner S, Kessler H. Synthesis and NMR studies of cyclopeptides containing a sugar amino Acid. Organic Letters. 4: 2501-2504. PMID 12123361 DOI: 10.1021/Ol026126D  0.336
2002 Jeschke B, Meyer J, Jonczyk A, Kessler H, Adamietz P, Meenen NM, Kantlehner M, Goepfert C, Nies B. RGD-peptides for tissue engineering of articular cartilage. Biomaterials. 23: 3455-3463. PMID 12099289 DOI: 10.1016/S0142-9612(02)00052-2  0.31
2002 Guthaus E, Bürgle M, Schmiedeberg N, Hocke S, Eickler A, Kramer MD, Sweep CG, Magdolen V, Kessler H, Schmitt M. uPA-silica-Particles (SP-uPA): a novel analytical system to investigate uPA-uPAR interaction and to test synthetic uPAR antagonists as potential cancer therapeutics. Biological Chemistry. 383: 207-16. PMID 11930939 DOI: 10.1515/Bc.2002.021  0.323
2002 Schmiedeberg N, Kessler H. Reversible backbone protection enables combinatorial solid-phase ring-closing metathesis reaction (RCM) in peptides. Organic Letters. 4: 59-62. PMID 11772090 DOI: 10.1021/Ol016891C  0.331
2002 Sukopp M, Marinelli L, Heller M, Brandl T, Goodman SL, Hoffmann RW, Kessler H. Designed beta-turn mimic based on the allylic-strain concept: Evaluation of structural and biological features by incorporation into a cyclic RGD peptide (cyclo(-L-arginylglycyl-L-α-aspartyl)) Helvetica Chimica Acta. 85: 4442-4452. DOI: 10.1002/Hlca.200290021  0.383
2001 Boer J, Gottschling D, Schuster A, Holzmann B, Kessler H. Design, Synthesis, and Biological Evaluation of α β Integrin Antagonists Based on β-D-Mannose as Rigid Scaffold. Angewandte Chemie (International Ed. in English). 40: 3870-3873. PMID 29712154 DOI: 10.1002/1521-3773(20011015)40:20<3870::Aid-Anie3870>3.0.Co;2-X  0.304
2001 Magdolen V, Bürgle M, Arroyo de Prada N, Schmiedeberg N, Riemer C, Schroeck F, Kellermann J, Degitz K, Wilhelm OG, Schmitt M, Kessler H. Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) Biological Chemistry. 382: 1197-1205. PMID 11592401 DOI: 10.1515/Bc.2001.150  0.329
2001 Locardi E, Stöckle M, Gruner S, Kessler H. Cyclic homooligomers from sugar amino acids: Synthesis, conformational analysis, and significance Journal of the American Chemical Society. 123: 8189-8196. PMID 11516268 DOI: 10.1021/Ja010181K  0.318
2001 Diercks T, Coles M, Kessler H. Applications of NMR in drug discovery Current Opinion in Chemical Biology. 5: 285-291. PMID 11479120 DOI: 10.1016/S1367-5931(00)00204-0  0.311
2001 Dehner A, Planker E, Gemmecker G, Broxterman QB, Bisson W, Formaggio F, Crisma M, Toniolo C, Kessler H. Solution Structure, Dimerization, and Dynamics of a Lipophilic α/310-Helical, Cα-Methylated Peptide. Implications for Folding of Membrane Proteins Journal of the American Chemical Society. 123: 6678-6686. PMID 11439056 DOI: 10.1021/Ja010635D  0.374
2001 Bayer T, Riemer C, Kessler H. A new strategy for the synthesis of cyclopeptides containing diaminoglutaric acid Journal of Peptide Science. 7: 250-261. PMID 11428546 DOI: 10.1002/Psc.306  0.312
2001 Truffault V, Coles M, Diercks T, Abelmann K, Eberhardt S, Lüttgen H, Bacher A, Kessler H. The solution structure of the N-terminal domain of riboflavin synthase. Journal of Molecular Biology. 309: 949-60. PMID 11399071 DOI: 10.1006/Jmbi.2001.4683  0.305
2001 Sulyok GAG, Gibson C, Goodman SL, Hölzemann G, Wiesner M, Kessler H. Solid-phase synthesis of a nonpeptide RGD mimetic library: New selective αvβ3 integrin antagonists Journal of Medicinal Chemistry. 44: 1938-1950. PMID 11384239 DOI: 10.1021/Jm0004953  0.301
2001 Heller M, Kessler H. NMR spectroscopy in drug design Pure and Applied Chemistry. 73: 1429-1436. DOI: 10.1351/Pac200173091429  0.307
1999 Diercks T, Coles M, Kessler H. An efficient strategy for assignment of cross-peaks in 3D heteronuclear NOESY experiments Journal of Biomolecular Nmr. 15: 177-180. PMID 20872110 DOI: 10.1023/A:1008367912535  0.314
1999 Koppitz M, Mathä B, Kessler H. Structure investigation of amphiphilic cyclopeptides in isotropic and anisotropic environments—a model study simulating peptide–membrane interactions Journal of Peptide Science. 5: 507-518. PMID 10587314 DOI: 10.1002/(Sici)1099-1387(199911)5:11<507::Aid-Psc219>3.0.Co;2-U  0.383
1999 Coles M, Diercks T, Liermann J, Gröger A, Rockel B, Baumeister W, Koretke KK, Lupas A, Peters J, Kessler H. The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element. Current Biology. 9: 1158-1168. PMID 10531028 DOI: 10.1016/S0960-9822(00)80017-2  0.315
1999 Dechantsreiter MA, Planker E, Mathä B, Lohof E, Hölzemann G, Jonczyk A, Goodman SL, Kessler H. N-methylated cyclic RGD peptides as highly active and selective α(v)β3 integrin antagonists Journal of Medicinal Chemistry. 42: 3033-3040. PMID 10447947 DOI: 10.1021/Jm970832G  0.342
1999 Coles M, Diercks T, Muehlenweg B, Bartsch S, Zölzer V, Tschesche H, Kessler H. The solution structure and dynamics of human neutrophil gelatinase-associated lipocalin. Journal of Molecular Biology. 289: 139-57. PMID 10339412 DOI: 10.1006/Jmbi.1999.2755  0.339
1999 Kessler H, Konat R, Kurz M, Gilon C. Conformational design of bioactive peptides Collection of Czechoslovak Chemical Communications. 1: 86-94. DOI: 10.1135/Css199901086  0.332
1999 Orekhov VY, Korzhnev DM, Diercks T, Kessler H, Arseniev AS. 1H-15N NMR dynamic study of an isolated α-helical peptide (1–36)- bacteriorhodopsin reveals the equilibrium helix-coil transitions Journal of Biomolecular Nmr. 14: 345-356. DOI: 10.1023/A:1008356809071  0.347
1999 Gibson C, Goodman SL, Hahn D, Hölzemann G, Kessler H. Novel solid-phase synthesis of azapeptides and azapeptoides via Fmoc- strategy and its application in the synthesis of RGD-mimetics Journal of Organic Chemistry. 64: 7388-7394. DOI: 10.1021/Jo9906173  0.318
1998 Gschwind RM, Gemmecker G, Kessler H. A Spin System Labeled and Highly Resolved ed-H(CCO)NH-TOCSY Experiment for the Facilitated Assignment of Proton Side Chains in Partially Deuterated Samples. Journal of Biomolecular Nmr. 11: 191. PMID 20700828 DOI: 10.1023/A:1008233703362  0.309
1998 Balbach J, Seip S, Kessler H, Scharf M, Kashani-Poor N, Engels JW. Structure and dynamic properties of the single disulfide-deficient alpha-amylase inhibitor [C45A/C73A]tendamistat: an NMR study. Proteins. 33: 285-94. PMID 9779794 DOI: 10.1002/(Sici)1097-0134(19981101)33:2<285::Aid-Prot11>3.0.Co;2-G  0.304
1998 Schwaiger M, Lebendiker M, Yerushalmi H, Coles M, Gröger A, Schwarz C, Schuldiner S, Kessler H. NMR investigation of the multidrug transporter EmrE, an integral membrane protein. European Journal of Biochemistry / Febs. 254: 610-9. PMID 9688273 DOI: 10.1046/J.1432-1327.1998.2540610.X  0.322
1998 Gilon C, Huenges M, Mathä B, Gellerman G, Hornik V, Afargan M, Amitay O, Ziv O, Feller E, Gamliel A, Shohat D, Wanger M, Arad O, Kessler H. A backbone-cyclic, receptor 5-selective somatostatin analogue: synthesis, bioactivity, and nuclear magnetic resonance conformational analysis. Journal of Medicinal Chemistry. 41: 919-29. PMID 9526566 DOI: 10.1021/Jm970633X  0.332
1998 Gratias R, Konat R, Kessler H, Crisma M, Valle G, Polese A, Formaggio F, Toniolo C, Broxterman QB, Kamphuis J. First Step Toward the Quantitative Identification of Peptide 310-Helix Conformation with NMR Spectroscopy: NMR and X-ray Diffraction Structural Analysis of a Fully-Developed 310-Helical Peptide Standard Journal of the American Chemical Society. 120: 4763-4770. DOI: 10.1021/Ja9731478  0.39
1997 Berglechner F, Richter G, Fischer M, Backer A, Gschwind RM, Huenges M, Gemmecker G, Kessler H. Studies On The Nusb Protein Of Escherichia Coli : Expression And Determination Of Secondary-Structure Elements By Multinuclear Nmr Spectroscopy Febs Journal. 248: 338-346. PMID 9346286 DOI: 10.1111/J.1432-1033.1997.00338.X  0.318
1997 Bürgle M, Koppitz M, Riemer C, Kessler H, König B, Weidle UH, Kellermann J, Lottspeich F, Graeff H, Schmitt M, Goretzki L, Reuning U, Wilhelm O, Magdolen V. Inhibition of the interaction of urokinase-type plasminogen activator (uPA) with its receptor (uPAR) by synthetic peptides Biological Chemistry. 378: 231-237. PMID 9165076 DOI: 10.1515/Bchm.1997.378.3-4.231  0.348
1997 Lutz J, Romano-Götsch R, Escrieut C, Fourmy D, Mathä B, Müller G, Kessler H, Moroder L. Mapping of ligand binding sites of the cholecystokinin-B/gastrin receptor with lipo-gastrin peptides and molecular modeling. Biopolymers. 41: 799-817. PMID 9128441 DOI: 10.1002/(Sici)1097-0282(199706)41:7<799::Aid-Bip8>3.0.Co;2-K  0.351
1997 Wermuth J, Goodman SL, Jonczyk A, Kessler H. Stereoisomerism and biological activity of the selective and superactive α(v)β3 integrin inhibitor cyclo(-RGDfV-) and its retro-inverso peptide Journal of the American Chemical Society. 119: 1328-1335. DOI: 10.1021/Ja961908L  0.365
1997 Magdolen V, Bürgle M, Kessler H, Creutzburg S, Helmecke D, Reuning U, Graeff H, Wilhelm O, Scmitt M. 184 Inhibition of uPA/uPAR-interaction by cyclic uPA-derived peptides Fibrinolysis and Proteolysis. 11: 53. DOI: 10.1016/S0268-9499(97)80299-8  0.312
1997 Mechnich O, Kessler H. What are the structures of phakellistatin 2 and phakellistatin 4 Letters in Peptide Science. 4: 21-28. DOI: 10.1007/Bf02443551  0.307
1997 Mechnich O, Messier G, Kessler H, Bernd M, Kutscher B. Cyclic Heptapeptides Axinastatin 2, 3, and 4: Conformational analysis and evaluation of the biological potential† Helvetica Chimica Acta. 80: 1338-1354. DOI: 10.1002/Hlca.19970800503  0.381
1997 Koppitz M, Huenges M, Gratias R, Kessler H, Goodman SL, Jonczyk A. Synthesis of Unnatural Lipohilic N‐(9H‐Fluoren‐9‐ylmethoxy)carbonyl‐Substituted α‐Amino Acids and Their Incorporation into Cyclic RGD‐Peptides: A structure‐activity study Helvetica Chimica Acta. 80: 1280-1300. DOI: 10.1002/Hlca.19970800423  0.364
1997 Besse D, Siedler F, Diercks T, Kessler H, Moroder L. The Redox Potential of Selenocystine in Unconstrained Cyclic Peptides Angewandte Chemie. 36: 883-885. DOI: 10.1002/Anie.199708831  0.311
1996 Behrens S, Mathä B, Bitan G, Gilon C, Kessler H. Structure-activity relationship of the ring portion in backbone-cyclic C-terminal hexapeptide analogs of substance P. NMR and molecular dynamics. International Journal of Peptide and Protein Research. 48: 569-79. PMID 8985790 DOI: 10.1111/J.1399-3011.1996.Tb00876.X  0.353
1996 Michael K, Wittmann V, König W, Sandow J, Kessler H. S- and C-glycopeptide derivatives of an LH-RH agonist. International Journal of Peptide and Protein Research. 48: 59-70. PMID 8844264 DOI: 10.1111/J.1399-3011.1996.Tb01107.X  0.568
1996 Magdolen V, Rettenberger P, Koppitz M, Goretzkt L, Kessler H, Weidle UH, König B, Graeff H, Schmitt M, Wilhelm O. Systematic Mutational Analysis of the Receptor-Binding Region of the Human Urokinase-Type Plasminogen Activator Febs Journal. 237: 743-751. PMID 8647121 DOI: 10.1111/J.1432-1033.1996.0743P.X  0.302
1996 Kessler H, Gratias R, Hessler G, Gurrath M, Müller G. Conformation of cyclic peptides. Principle concepts and the design of selectivity and superactivity in bioactive sequences by 'spatial screening' Pure and Applied Chemistry. 68: 1201-1205. DOI: 10.1351/Pac199668061201  0.376
1996 Roedern EGv, Lohof E, Hessler G, Hoffmann aM, Kessler H. Synthesis and Conformational Analysis of Linear and Cyclic Peptides Containing Sugar Amino Acids Journal of the American Chemical Society. 118: 10156-10167. DOI: 10.1021/Ja961068A  0.383
1996 Haubner R, Schmitt W, Hölzemann G, Goodman SL, Jonczk A, Kessler H. Cyclic RGD peptides containing β-turn mimetics Journal of the American Chemical Society. 118: 7881-7891. DOI: 10.1021/Ja9608757  0.327
1996 Haubner R, Gratias R, Diefenbach B, Goodman SL, Jonczyk A, Kessler H. Structural and functional aspects of RGD-containing cyclic pentapeptides as highly potent and selective integrin α(v)β3 antagonists Journal of the American Chemical Society. 118: 7461-7472. DOI: 10.1021/Ja9603721  0.32
1996 Schmitt W, Zanotti G, Wieland T, Kessler H. Conformation of Different S-Deoxo-Xaa3-amaninamide Analogues in DMSO Solution as Determined by NMR Spectroscopy. Strong CD Effects Induced by βI, βII Conformational Change Journal of the American Chemical Society. 118: 4380-4387. DOI: 10.1021/Ja9529706  0.389
1995 Kessler H, Diefenbach B, Finsinger D, Geyer A, Gurrath M, Goodman SL, Hölzemann G, Haubner R, Jonczyk A, Müller G, von Roedern EG, Wermuth J. Design of superactive and selective integrin receptor antagonists containing the RGD sequence Letters in Peptide Science. 2: 155-160. DOI: 10.1007/Bf00119142  0.345
1995 Bitan G, Behrens S, Mathä B, Mashriki Y, Hanani M, Kessler H, Gilon C. New backbone cyclic substance P analogs Letters in Peptide Science. 2: 121-124. DOI: 10.1007/Bf00119137  0.328
1995 Konat RK, Mathä B, Winkler J, Kessler H. Axinastatin 1 or malaysiatin? proof of constitution and 3D structure in solution of a cyclic heptapeptide with cytostatic properties Liebigs Annalen. 1995: 765-774. DOI: 10.1002/Jlac.1995199505112  0.388
1995 Eberstadt M, Guba W, Kessler H, Kogler H, Mierke DF. Conformation and dynamics of dimeric ureido-balhimycin Biopolymers. 36: 429-437. DOI: 10.1002/Bip.360360406  0.57
1995 Eberstadt M, Gemmecker G, Mierke DF, Kessler H. Scalar coupling constants - Their analysis and their application for the elucidation of structures Angewandte Chemie (International Edition in English). 34: 1671-1695. DOI: 10.1002/Anie.199516711  0.533
1995 Eberstadt M, Gemmecker G, Mierke DF, Kessler H. Skalare Kopplungen – ihre Analyse und ihre Verwendung zur Strukturaufklärung Angewandte Chemie. 107: 1813-1838. DOI: 10.1002/Ange.19951071604  0.556
1994 Jahnke W, Mierke DF, Beress L, Kessler H. Structure of cobra cardiotoxin CTXI as derived from nuclear magnetic resonance spectroscopy and distance geometry calculations Journal of Molecular Biology. 240: 445-458. PMID 8046750 DOI: 10.1006/Jmbi.1994.1460  0.558
1994 Mierke DF, Huber T, Kessler H. Coupling constants again: Experimental restraints in structure refinement Journal of Computer-Aided Molecular Design. 8: 29-40. PMID 8035210 DOI: 10.1007/Bf00124347  0.551
1994 Seip S, Balbach J, Behrens S, Kessler H, Flükiger K, de Meyer R, Erni B. Mannose transporter of Escherichia coli. Backbone assignments and secondary structure of the IIA domain of the IIABMan subunit. Biochemistry. 33: 7174-83. PMID 8003484 DOI: 10.1021/Bi00189A021  0.304
1994 Mierke DF, Geyer A, Kessler H. Coupling constants and hydrogen bonds as experimental restraints in a distance geometry refinement protocol International Journal of Peptide and Protein Research. 44: 325-331. PMID 7875934 DOI: 10.1111/J.1399-3011.1994.Tb01016.X  0.587
1994 Müller G, Gurrath M, Kessler H. Pharmacophore refinement of gpIIb/IIIa antagonists based on comparative studies of antiadhesive cyclic and acyclic RGD peptides. Journal of Computer-Aided Molecular Design. 8: 709-730. PMID 7738606 DOI: 10.1007/Bf00124017  0.353
1994 Grdadolnik SG, Mierke DF, Byk G, Zeltser I, Gilon C, Kessler H. Comparison of the conformation of active and nonactive backbone cyclic analogs of substance P as a tool to elucidate features of the bioactive conformation: NMR and molecular dynamics in DMSO and water. Journal of Medicinal Chemistry. 37: 2145-52. PMID 7518522 DOI: 10.1021/Jm00040A005  0.568
1994 Moroder L, Romano R, Guba W, Mierke DF, Kessler H, Delporte C, Winand J, Christophe J. New evidence for a membrane-bound pathway in hormone receptor binding. Biochemistry. 32: 13551-9. PMID 7504952 DOI: 10.1021/Bi00212A022  0.576
1994 Geyer A, Mueller G, Kessler H. Conformational Analysis of a Cyclic RGD Peptide Containing a .psi.[CH2-NH] Bond: A Positional Shift in Backbone Structure Caused by a Single Dipeptide Mimetic Journal of the American Chemical Society. 116: 7735-7743. DOI: 10.1021/Ja00096A034  0.619
1994 Guba W, Haessner R, Breipohl G, Henke S, Knolle J, Santagada V, Kessler H. Combined Approach of NMR and Molecular Dynamics within a biphasic Membrane Mimetic: Conformation and Orientation of the Bradykinin Antagonist Hoe 140 Journal of the American Chemical Society. 116: 7532-7540. DOI: 10.1021/Ja00096A009  0.3
1994 Mierke DF, Kurz M, Kessler H. Peptide flexibility and calculations of an ensemble of molecules Journal of the American Chemical Society. 116: 1042-1049. DOI: 10.1021/Ja00082A027  0.604
1994 Köck M, Müller G, Kessler H. Computational Approach to the Receptor‐Bound Conformation of Cyclosporin A Helvetica Chimica Acta. 77: 171-181. DOI: 10.1002/Hlca.19940770120  0.334
1994 Mierke DF, Scheek RM, Kessler H. Coupling constants as restraints in ensemble distance driven dynamics Biopolymers. 34: 559-563. DOI: 10.1002/Bip.360340411  0.52
1993 Müller G, Gurrath M, Kurz M, Kessler H. βVI Turns in peptides and proteins: A model peptide mimicry Proteins. 15: 235-251. PMID 8456095 DOI: 10.1002/Prot.340150303  0.392
1993 Moroder L, Musiol HJ, Kocher K, Bali JP, Schneider CH, Guba W, Muller G, Mierke DF, Kessler H. Synthetic immunogens. The effect of the conformational space on biological and immunological responses to dimeric hormone constructs European Journal of Biochemistry. 212: 325-333. PMID 8444171 DOI: 10.1111/J.1432-1033.1993.Tb17665.X  0.589
1993 Oijen AHv, Behrens S, Mierke DF, Kessler H, Boom JHv, Liskamp RMJ. Synthesis and structure of cyclic phosphopeptides containing a phosphodiester linkage Journal of Organic Chemistry. 58: 3722-3730. DOI: 10.1021/Jo00066A026  0.577
1993 Schüler W, Schmieder P, Kessler H, Christians U, Holze I, Sewing K, Schiebel H. Structural Investigations of 13-O-Demethyl-FK506 and Its Isomers Generated byin vitroMetabolism of FK506 Using Human-Liver Microsomes Helvetica Chimica Acta. 76: 2288-2302. DOI: 10.1002/Hlca.19930760614  0.311
1993 Konat RK, Mierke DF, Kessler H, Kutscher B, Bernd M, Voegeli R. Synthesis and Solvent Effects on the Conformation of Hymenistatin 1 Helvetica Chimica Acta. 76: 1649-1666. DOI: 10.1002/Hlca.19930760422  0.372
1993 Kessler H, Haessner R, Schüler W. Structure of Rapamycin: An NMR and Molecular‐Dynamics Investigation Helvetica Chimica Acta. 76: 117-130. DOI: 10.1002/Hlca.19930760106  0.343
1993 Gerz M, Matter H, Kessler H. S‐Glycosylated Cyclic Peptides Angewandte Chemie. 32: 269-271. DOI: 10.1002/Anie.199302691  0.312
1992 Kessler H, Mronga S, Müller G, Moroder L, Huber R. Conformational analysis of a IgG1 hinge peptide derivative in solution determined by NMR spectroscopy and refined by restrained molecular dynamics simulations. Biopolymers. 31: 1189-204. PMID 1665090 DOI: 10.1002/Bip.360311007  0.41
1992 Kuntz DA, Osowski R, Schudok M, Wierenga RK, Muller K, Kessler H, Opperdoes FR. Inhibition of triosephosphate isomerase from Trypanosoma brucei with cyclic hexapeptides European Journal of Biochemistry. 207: 441-447. PMID 1633802 DOI: 10.1111/J.1432-1033.1992.Tb17069.X  0.338
1992 Schmieder P, Kessler H. Determination of the ϕ angle in a peptide backbone by NMR spectroscopy with a combination of homonuclear and heteronuclear coupling constants Biopolymers. 32: 435-440. PMID 1623139 DOI: 10.1002/Bip.360320421  0.344
1992 Kessler H, Mierke DF, Saulitis J, Seip S, Steuernagel S, Wein T, Will M. The structure of Ro 09-0198 in different environments Biopolymers. 32: 427-433. PMID 1623138 DOI: 10.1002/Bip.360320420  0.568
1992 Gurrath M, Müller G, Kessler H, Aumailley M, Timpl R. Conformation/activity studies of rationally designed potent anti-adhesive RGD peptides. Febs Journal. 210: 911-921. PMID 1483474 DOI: 10.1111/J.1432-1033.1992.Tb17495.X  0.378
1992 Mierke DF, Kessler H. Combined use of homo- and heteronuclear coupling constants as restraints in molecular dynamics simulations Biopolymers. 32: 1277-1282. PMID 1420958 DOI: 10.1002/Bip.360321003  0.558
1992 Mierke DF, Durr H, Kessler H, Jung G. Neuropeptide Y. Optimized solid-phase synthesis and conformational analysis in trifluoroethanol European Journal of Biochemistry. 206: 39-48. PMID 1316841 DOI: 10.1111/J.1432-1033.1992.Tb16899.X  0.6
1992 Mierke DF, Grdadolnik SG, Kessler H. Use of one-bond C.alpha.-H.alpha. coupling constants as restraints in MD simulations Journal of the American Chemical Society. 114: 8283-8284. DOI: 10.1021/Ja00047A045  0.518
1992 Saulitis J, Mierke DF, Byk G, Gilon C, Kessler H. Conformation of cyclic analogues of substance P: NMR and molecular dynamics in dimethyl sulfoxide Journal of the American Chemical Society. 114: 4818-4827. DOI: 10.1021/Ja00038A054  0.561
1992 Kessler H, Matter H, Gemmecker G, Kottenhahn M, Bats JW. Structure and dynamics of synthetic O-glycosylated cyclopeptide in solution determined by NMR spectroscopy and MD calculations Journal of the American Chemical Society. 114: 4805-4818. DOI: 10.1021/Ja00038A053  0.333
1992 Koeck M, Kessler H, Seebach D, Thaler A. Novel backbone conformation of cyclosporin A: the complex with lithium chloride Journal of the American Chemical Society. 114: 2676-2686. DOI: 10.1021/Ja00033A048  0.324
1992 Kessler H. Struktur Und Design Von Cyclopeptiden Zur Regulation Des Immunsystems Journal Fur Praktische Chemie-Chemiker-Zeitung. 334: 549-557. DOI: 10.1002/Prac.19923340702  0.354
1992 Eberstadt M, Mierke DF, Kock M, Kessler H. Peptide conformation from coupling constants: Scalar couplings as restraints in MD simulations Helvetica Chimica Acta. 75: 2583-2592. DOI: 10.1002/Hlca.19920750813  0.561
1992 Unverzagt C, Geyer A, Kessler H. Chain elongation of thiodipeptides with proteases Angewandte Chemie. 31: 1229-1230. DOI: 10.1002/Anie.199212291  0.546
1992 Kessler H, Matter H, Geyer A, Diehl H, Köck M, Kurz G, Opperdoes FR, Callens M, Wierenga RK. Selective Inhibition of Trypanosomal Triosephosphate Isomerase by a Thiopeptide Angewandte Chemie. 31: 328-330. DOI: 10.1002/Anie.199203281  0.572
1992 Kurz M, Mierke DF, Kessler H. Calculation of Molecular Dynamics for Peptides in Dimethyl Sulfoxide: Elimination of Vacuum Effects Angewandte Chemie. 31: 210-212. DOI: 10.1002/Anie.199202101  0.319
1992 Unverzagt C, Geyer A, Kessler H. Racemisierungsfreie Kettenverlängerung von Thiodipeptiden mit Proteasen Angewandte Chemie. 104: 1231-1233. DOI: 10.1002/Ange.19921040919  0.55
1992 Kessler H, Matter H, Geyer A, Diehl H, Köck M, Kurz G, Opperdoes FR, Callens M, Wierenga RK. Selektive Inhibierung der trypanosomalen Triosephosphat-Isomerase durch ein Thiopeptid Angewandte Chemie. 104: 343-345. DOI: 10.1002/Ange.19921040331  0.563
1992 Kurz M, Mierke DF, Kessler H. Moleküldynamikrechnungen für Peptide in Dimethylsulfoxid: Eliminierung von Vakuumeffekten Angewandte Chemie. 104: 213-214. DOI: 10.1002/Ange.19921040226  0.56
1991 Schmieder P, Kurz M, Kessler H. Determination of heteronuclear long-range couplings to heteronuclei in natural abundance by two- and three-dimensional NMR spectroscopy Journal of Biomolecular Nmr. 1: 403-420. PMID 1841708 DOI: 10.1007/Bf02192863  0.303
1991 Aumailley M, Gurrath M, Müller G, Calvete J, Timpl R, Kessler H. Arg‐Gly‐Asp constrained within cyclic pentapoptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1 Febs Letters. 291: 50-54. PMID 1718779 DOI: 10.1016/0014-5793(91)81101-D  0.378
1991 Mierke DF, Kessler H. Molecular dynamics with dimethyl sulfoxide as a solvent. Conformation of a cyclic hexapeptide Journal of the American Chemical Society. 113: 9466-9470. DOI: 10.1021/Ja00025A007  0.556
1991 Kessler H, Matter H, Gemmecker G, Kling A, Kottenhahn M. Solution structure of a synthetic N-glycosylated cyclic hexapeptide determined by NMR spectroscopy and MD calculations Journal of the American Chemical Society. 113: 7550-7563. DOI: 10.1021/Ja00020A016  0.329
1991 Kessler H, Schmieder P, Köck M, Reggelin M. Selection of methyl resonances in proton-detected heteronuclear shift correlation, the hqqc experiment Journal of Magnetic Resonance. 91: 375-379. DOI: 10.1016/0022-2364(91)90199-4  0.587
1991 Kessler H, Mronga S, Kutscher B, Müller A, Sheldrick WS. Synthesis of the 4‐Pyridine Analog of Kostanecki's Triketone. Determination of Constitution and Stereochemistry by 2D‐NMR Spectroscopy and X‐ray Structural Analysis European Journal of Organic Chemistry. 1991: 1337-1341. DOI: 10.1002/Jlac.1991199101228  0.319
1991 Seebach D, Ko SY, Kessler H, Köck M, Reggelin M, Schmieder P, Walkinshaw MD, Bölsterli JJ, Bevec D. Thiocyclosporins: Preparation, Solution and Crystal Structure, and Immunosuppressive Activity Helvetica Chimica Acta. 74: 1953-1990. DOI: 10.1002/Hlca.19910740833  0.643
1991 Kessler H, Schmieder P. Heteronuclear two- and three-dimensional NMR spectroscopy of 13C in natural abundance by multiplicity selection and editing : application to peptides Biopolymers. 31: 621-629. DOI: 10.1002/Bip.360310606  0.317
1991 Kessler H, Mierke DF, Donald D, Furber M. Auf dem Weg zum Verständnis der Immunsuppression Angewandte Chemie. 103: 968-969. DOI: 10.1002/Ange.19911030808  0.511
1990 Lautz J, Kessler H, van Gunsteren WF, Weber HP, Wenger RM. On the dependence of molecular conformation on the type of solvent environment: a molecular dynamics study of cyclosporin A. Biopolymers. 29: 1669-87. PMID 2386812 DOI: 10.1002/Bip.360291214  0.307
1990 Kessler H, Gehrke M, Lautz J, Köck M, Seebach D, Thaler A. Complexation and medium effects on the conformation of cyclosporin A studied by NMR spectroscopy and molecular dynamics calculations. Biochemical Pharmacology. 40: 169-73. PMID 2164815 DOI: 10.1016/0006-2952(90)90192-N  0.334
1990 Karuso P, Kessler H, Mierke DF. Solution structure of FK 506 from nuclear magnetic resonance and molecular dynamics Journal of the American Chemical Society. 112: 9434-9436. DOI: 10.1021/Ja00181A078  0.676
1990 Kessler H, Schmieder P, Oschkinat H. 3D Heteronuclear NMR techniques for carbon-13 in natural abundance Journal of the American Chemical Society. 112: 8599-8600. DOI: 10.1021/Ja00179A064  0.507
1990 Kessler H, Anders U, Schudok M. An unexpected cis peptide bond in the minor conformation of a cyclic hexapeptide containing only secondary amide bonds Journal of the American Chemical Society. 112: 5908-5916. DOI: 10.1021/Ja00172A003  0.315
1990 Kessler H, Schmieder P, Köck M, Kurz M. Improved Resolution in Proton-Detected Heteronuclear Long-Range Correlation Journal of Magnetic Resonance. 88: 615-618. DOI: 10.1016/0022-2364(90)90293-I  0.301
1990 Kessler H, Schmieder P, Bermel W. Complete assignment of the noncarbonylic carbon‐13 resonances of Tendamistat Biopolymers. 30: 465-475. DOI: 10.1002/Bip.360300323  0.338
1990 Schmieder P, Kessler H, Oschkinat H. Schnelle Heterokern-3D-NMR-Spektroskopie Angewandte Chemie. 102: 588-589. DOI: 10.1002/Ange.19901020534  0.515
1989 Kessler H, Bats J, Wagner K, Will M. Conformational analysis of cyclic peptides in solution. Biopolymers. 28: 385-395. PMID 2720115 DOI: 10.1002/Bip.360280136  0.379
1989 Hofmann M, Gehrke M, Bermel W, Kessler H. Proton‐detected C,H correlation NMR techniques for the complete assignment of all proton and carbon resonances of a cyclic peptide Magnetic Resonance in Chemistry. 27: 877-886. DOI: 10.1002/Mrc.1260270911  0.389
1989 Kessler H, Bats JW, Lautz J, Müller A. Conformation of Antamanide European Journal of Organic Chemistry. 1989: 913-928. DOI: 10.1002/Jlac.198919890243  0.37
1989 Kessler H, Müller A, Pook K. Assignment of All Proton, Carbon, and Nitrogen NMR Signals of Antamanide in Chloroform Solution European Journal of Organic Chemistry. 1989: 903-912. DOI: 10.1002/Jlac.198919890242  0.379
1989 Kessler H, Kerssebaum R, Klein AG, Obermeier R, Will M. Berichtigung zu dem Beitrag Peptidkonformationen, 50. - Synthese und Konformationsanalyse von cyclischen Alanin-Analogen des Thymopoietins durch NMR-Spektroskopie und Molecular-Dynamics-Rechnungen im Vakuum und in Lösung European Journal of Organic Chemistry. 1989: 413-413. DOI: 10.1002/Jlac.198919890173  0.314
1989 Kessler H, Klein AG, Obermeier R, Will M. Peptidkonformationen, 50. Synthese und Konformationsanalyse von cyclischen Alanin‐Analogen des Thymopoietins durch NMR‐Spektroskopie und Molecular‐Dynamics‐Rechnungen im Vakuum und in Lösung European Journal of Organic Chemistry. 1989: 269-294. DOI: 10.1002/Jlac.198919890150  0.397
1989 Kessler H, Will M, Antel J, Beck H, Sheldrick GM. Conformational Analysis of Didemnins. A multidisciplinary approach by means of X-Ray, NMR, molecular-dynamics, and molecular-mechanics techniques Helvetica Chimica Acta. 72: 530-555. DOI: 10.1002/Hlca.19890720316  0.343
1988 Kessler H, Griesinger C, Lautz J, Muller A, Vangunsteren W, Berendsen H. Conformational Dynamics Detected By Nuclear Magnetic-Resonance Noe Values And J-Coupling Constants Journal of the American Chemical Society. 110: 3393-3396. DOI: 10.1021/Ja00219A008  0.463
1988 Kessler H, Bats JW, Griesinger C, Koll S, Will M, Wagner K. Peptide conformations. 46. Conformational analysis of a superpotent cytoprotective cyclic somatostatin analog Journal of the American Chemical Society. 110: 1033-1049. DOI: 10.1021/Ja00212A007  0.529
1988 Kessler H, Gemmecker G, Haase B. Relayed-NOE experiments in the rotating frame for sequence analysis of peptides Journal of Magnetic Resonance. 77: 401-408. DOI: 10.1016/0022-2364(88)90192-8  0.356
1988 Kessler H, Will M, Sheldrick GM, Antel J. Assignment of proton and carbon NMR signals of didemnin A in solution Magnetic Resonance in Chemistry. 26: 501-506. DOI: 10.1002/Mrc.1260260613  0.34
1988 Kessler H, Steuernagel S, Will M, Jung G, Kellner R, Gillessen D, Kamiyama T. The Structure of the Polycyclic Nonadecapeptide Ro 09-0198† Helvetica Chimica Acta. 71: 1924-1929. DOI: 10.1002/Hlca.19880710811  0.328
1988 Kessler H, Gemmecker G, Steuernagel S. NOESY‐TOCSY, an Advantageous 2D NMR Technique for the Analysis of Peptide Sequences Angewandte Chemie. 27: 564-566. DOI: 10.1002/Anie.198805641  0.34
1988 Kessler H, Gehrke M, Griesinger C. Two‐Dimensional NMR Spectroscopy: Background and Overview of the Experiments [New Analytical Methods (36)] Angewandte Chemie. 27: 490-536. DOI: 10.1002/Anie.198804901  0.487
1988 Kessler H, Gehrke M, Griesinger C. Zweidimensionale NMR‐Spektroskopie, Grundlagen und Übersicht über die Experimente Angewandte Chemie. 100: 507-554. DOI: 10.1002/Ange.19881000407  0.49
1987 Lautz J, Kessler H, Boelens R, Kaptein R, van Gunsteren WF. Conformational analysis of a cyclic thymopoietin-analogue by 1H n.m.r. spectroscopy and restrained molecular dynamics simulations. International Journal of Peptide and Protein Research. 30: 404-14. PMID 3692686 DOI: 10.1111/J.1399-3011.1987.Tb03348.X  0.34
1987 Lautz J, Kessler H, Kaptein R, Gunsteren WFv. Molecular dynamics simulations of cyclosporin A: The crystal structure and dynamic modelling of a structure in apolar solution based on NMR data Journal of Computer-Aided Molecular Design. 1: 219-241. PMID 3504965 DOI: 10.1007/Bf01677046  0.309
1987 Kessler H, Griesinger C, Wagner K. Peptide conformations. 42. Conformation of side chains in peptides using heteronuclear coupling constants obtained by two-dimensional NMR spectroscopy Journal of the American Chemical Society. 109: 6927-6933. DOI: 10.1021/Ja00257A004  0.54
1987 Kessler H, Griesinger C, Kerssebaum R, Wagner K, Ernst RR. Separation of cross-relaxation and J cross-peaks in 2D rotating-frame NMR spectroscopy Journal of the American Chemical Society. 109: 607-609. DOI: 10.1021/Ja00236A063  0.581
1987 Anders U, Gemmecker G, Kessler H, Griesinger C. Conformational analysis of amino acid side chains in peptides by quantitative evaluation of cross-peaks in COLOC-spectra Fresenius Journal of Analytical Chemistry. 327: 72-73. DOI: 10.1007/Bf00474581  0.507
1987 Kessler H, Griesinger C, Zimmermann G. Comparison of four pulse sequences for the routine application of proton‐carbon shift correlation Magnetic Resonance in Chemistry. 25: 579-583. DOI: 10.1002/Mrc.1260250706  0.46
1987 Bermel W, Griesinger C, Kessler H, Wagner K. Assignment of carbonyl groups and sequence analysis in peptides by inverse correlation using long‐range couplings Magnetic Resonance in Chemistry. 25: 325-326. DOI: 10.1002/Mrc.1260250410  0.512
1987 Kessler H, Steuernagel S, Gillessen D, Kamiyama T. Complete Sequence Determination and Localisation of One Imino and Three Sulfide Bridges of the Nonadecapeptide Ro 09–0198 by Homonuclear 2D-NMR Spectroscopy. The DQF-RELAYED-NOESY-Experiment† Helvetica Chimica Acta. 70: 726-741. DOI: 10.1002/Hlca.19870700322  0.304
1986 Kessler H, Bermel W, Griesinger C, Hertl P, Streich E, Rieker A. Additions and Corrections - Assignments of the Carbon Resonances in tert-Butylated 2-Naphthols by the Two-Dimensional C-Relayed H,C-COSY Technique. Journal of Organic Chemistry. 51: 4326-4326. DOI: 10.1021/Jo00372A612  0.457
1986 Kessler H, Bermel W, Griesinger C, Hertl P, Streich E, Rieker A. Assignments of the carbon resonances in tert-butylated 2-naphthols by the two-dimensional carbon-relayed hydrogen,carbon-COSY technique Journal of Organic Chemistry. 51: 596-601. DOI: 10.1021/Jo00355A005  0.429
1986 Kessler H, Oschkinat H, Griesinger C, Bermel W. Transformation of homonuclear two-dimensional NMR techniques into one-dimensional techniques using Gaussian pulses Journal of Magnetic Resonance (1969). 70: 106-133. DOI: 10.1016/0022-2364(86)90366-5  0.609
1986 Kessler H, Müller A. Peptidkonformationen, 41. Eine ungewöhnliche Konformation des cyclischen Pentapeptids cyclo(‐Pro‐Pro‐Phe‐Phe‐Gly‐) in DMSO European Journal of Organic Chemistry. 1986: 1687-1704. DOI: 10.1002/Jlac.198619861003  0.398
1986 Kessler H, Kutscher B. Peptidkonformationen, 40. Cyclische Hexapeptidanaloge des Thymopoietins Synthese und Konformationsstudien European Journal of Organic Chemistry. 1986: 914-931. DOI: 10.1002/Jlac.198619860509  0.335
1986 Kessler H, Kutscher B, Klein A. Peptidkonformationen, 39. NMR-Studien zur Konformation von Cyclopentapeptidanalogen des Thymopoietins European Journal of Organic Chemistry. 1986: 893-913. DOI: 10.1002/Jlac.198619860508  0.379
1986 Kessler H, Kutscher B. Synthese von cyclischen Pentapeptidanalogen des Thymopoietins. – Cyclisierungen mit Carbodiimid und 4‐(Dimethylamino)pyridin European Journal of Organic Chemistry. 1986: 869-892. DOI: 10.1002/Jlac.198619860507  0.339
1986 Kessler H, Kutscher B, Klein A. Peptide Conformations. Part 39. NMR Studies of the Conformation of Cyclic Pentapeptide Analogues of Thymopoietin. Cheminform. 17. DOI: 10.1002/Chin.198636325  0.39
1986 Kessler H, Bermel W, Griesinger C, Hertl P, Streich E, Rieker A. Assignments of the Carbon Resonances in tert-Butylated 2-Naphthols by the Two-Dimensional C-Relayed H,C-COSY Technique. Cheminform. 17. DOI: 10.1002/Chin.198636049  0.454
1986 Kessler H, Bermel W, Griesinger C, Kolar C. NMR Spectroscopic Elucidation of Constitutions of Glycopeptides by the COLOC Technique. Cheminform. 17. DOI: 10.1002/Chin.198630041  0.471
1986 QUINKERT G, HEIM N, BATS JW, OSCHKINAT H, KESSLER H. ChemInform Abstract: Structure of the Lichen Macrolide (+)-Aspicilin Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198609061  0.488
1986 Kessler H, Bermel W, Griesinger C, Kolar C. The Elucidation of the Constitution of Glycopeptides by the NMR Spectroscopic COLOC Technique Angewandte Chemie. 25: 342-344. DOI: 10.1002/Anie.198603421  0.471
1985 Kessler H, Bermel W, Griesinger C. Recognition of NMR proton spin systems of cyclosporin A via heteronuclear proton-carbon long-range couplings Journal of the American Chemical Society. 107: 1083-1084. DOI: 10.1021/Ja00290A068  0.46
1985 Kessler H, Kutscher B. Synthesis and NMR investigation of cyclic pentapeptide analogues of thymopentin Tetrahedron Letters. 26: 177-180. DOI: 10.1016/S0040-4039(00)61873-7  0.346
1985 Kessler H, Bermel W, Griesinger C. Determination of carbon-carbon connectivities, assignment of quaternary carbons, and extraction of carbon-carbon coupling constants by carbon-relayed hydrogen-carbon spectroscopy Journal of Magnetic Resonance. 62: 573-579. DOI: 10.1016/0022-2364(85)90231-8  0.47
1985 Kessler H, Müller A, Oschkinat H. Differences andsums of traces within,COSY spectra (DISCO) for the extraction of coupling constants: ‘Decoupling’ after the measurement Magnetic Resonance in Chemistry. 23: 844-852. DOI: 10.1002/Mrc.1260231012  0.518
1985 Kessler H, Bernd M. Peptidkonformationen, 36 Konformationsuntersuchungen an vier cyclischen Heptapeptiden durch NMR‐Spektroskopie European Journal of Organic Chemistry. 1985: 1145-1167. DOI: 10.1002/Jlac.198519850605  0.385
1985 Loosli H, Kessler H, Oschkinat H, Weber H, Petcher TJ, Widmer A. Peptide conformations. Part 31. The conformation of cyclosporin a in the crystal and in solution Helvetica Chimica Acta. 68: 682-704. DOI: 10.1002/Hlca.19850680319  0.55
1985 Kessler H, Loosli H, Oschkinat H. Peptide conformations. Part 30. Assignment of the1H-,13C-, and15N-NMR spectra of cyclosporin A in CDCl3 and C6D6 by a combination of homo- and heteronuclear two-dimensional techniques Helvetica Chimica Acta. 68: 661-681. DOI: 10.1002/Hlca.19850680318  0.546
1985 LOOSLI H, KESSLER H, OSCHKINAT H, WEBER H, PETCHER TJ, WIDMER A. ChemInform Abstract: PEPTIDE CONFORMATIONS. PART 31. THE CONFORMATION OF CYCLOSPORIN A IN THE CRYSTAL AND IN SOLUTION Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198535047  0.545
1985 KESSLER H, LOOSLI H, OSCHKINAT H. ChemInform Abstract: PEPTIDE CONFORMATIONS. PART 30. ASSIGNMENT OF THE PROTON, CARBON-13, NITROGEN-15 NMR SPECTRA OF CYCLOSPORIN A IN D-CHLOROFORM AND D6-BENZENE BY A COMBINATION OF HOMO- AND HETERONUCLEAR TWO-DIMENSIONAL TECHNIQUES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198535042  0.566
1985 Kessler H, Bermel W, Griesinger C. Recognition Of Nmr Proton Spin Systems Of Cyclosporin A Via Heteronuclear Proton-Carbon Long-Range Couplings Cheminform. 16. DOI: 10.1002/Chin.198527051  0.46
1985 Quinkert G, Heim N, Bats JW, Oschkinat H, Kessler H. The Structure of the Lichen Macrolide(+)-Aspicilin Angewandte Chemie International Edition in English. 24: 987-988. DOI: 10.1002/Anie.198509871  0.478
1985 Kessler H, Oschkinat H. Simplification of Spectra for the Determination of Coupling Constants from Homonuclear Correlated 2D NMR Spectra Angewandte Chemie International Edition in English. 24: 690-692. DOI: 10.1002/Anie.198506901  0.533
1985 Quinkert G, Heim N, Bats JW, Oschkinat H, Kessler H. Die Struktur des Flechten-Makrolids (+)-Aspicilin Angewandte Chemie. 97: 985-986. DOI: 10.1002/Ange.19850971125  0.468
1985 Kessler H, Oschkinat H. Spektrenvereinfachung zur Ermittlung von Kopplungskonstanten aus homonuclear-korrelierten 2D-NMR-Spektren Angewandte Chemie. 97: 689-690. DOI: 10.1002/Ange.19850970811  0.514
1984 Kessler H, Griesinger C, Zarbock J, Loosli HR. Assignment of carbonyl carbons and sequence analysis in peptides by heteronuclear shift correlation via small coupling constants with broadband decoupling in t1 (COLOC) Journal of Magnetic Resonance. 57: 331-336. DOI: 10.1016/0022-2364(84)90136-7  0.495
1984 Kessler H, Griesinger C, Lautz J. Determination Of The Connectivities Of Weak Proton-Carbon Couplings With A Variation Of The Two-Dimensional Nmr Technique Cheminform. 15. DOI: 10.1002/Chin.198440043  0.478
1984 KESSLER H, OSCHKINAT H, ZIMMERMANN G, MOEHRLE H, BIEGHOLDT M, ARZ W, FOERSTER H. ChemInform Abstract: APPLICATION OF HIGH-RESOLUTION SOLID-STATE NMR SPECTROSCOPY TO THE DETERMINATION OF THE RING-CHAIN TAUTOMERISM Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198418077  0.523
1984 Kessler H, Oschkinat H, Zimmermann G, Möhrle H, Biegholdt M, Arz W, Förster H. Anwendung der hochaufgelösten Festkörper-NMR-Spektroskopie zur Bestimmung der Ring-Ketten-Tautomerie Chemische Berichte. 117: 702-709. DOI: 10.1002/Cber.19841170223  0.562
1984 Kessler H, Griesinger C, Lautz J. Determination of Connectivities via Small Proton‐Carbon Couplings with a New Two‐Dimensional NMR Technique Angewandte Chemie. 23: 444-445. DOI: 10.1002/Anie.198404441  0.469
1984 Kessler H, Griesinger C, Lautz J. Bestimmung von Konnektivitäten über kleine Protonen‐Kohlenstoff‐Kopplungen mit einer neuen zweidimensionalen NMR‐Technik Angewandte Chemie. 96: 434-435. DOI: 10.1002/Ange.19840960618  0.463
1983 De Leeuw FAAM, Altona C, Kessler H, Bermel W, Friedrich A, Krack G, Hull WE. Peptide conformations. 20. Conformational analysis of proline rings from proton spin-spin coupling constants and force-field calculations: application to three cyclic tripeptides Journal of the American Chemical Society. 105: 2237-2246. DOI: 10.1021/Ja00346A023  0.32
1983 Kessler H, Oschkinat H, Sørensen O, Kogler H, Ernst R. Multiple-quantum-filtered homonuclear J,δ spectra Journal of Magnetic Resonance (1969). 55: 329-333. DOI: 10.1016/0022-2364(83)90244-5  0.594
1983 Kessler H, Kutscher B, Mager G, Grell E. Synthese des Streptogramin‐B‐analogen Cyclodepsipeptids cyclo[‐(Boc)Ser‐D‐Abu‐Pro‐(Me)Phe‐Pip‐Phg‐O‐] European Journal of Organic Chemistry. 1983: 1541-1550. DOI: 10.1002/Jlac.198319830910  0.323
1983 Kessler H, Kogler H. Peptidkonformationen, 26 Ein- und zweidimensionale H-NMR-Untersuchungen zur Konformation der beiden cyclischen Pentapeptide cyclo-[Pro-Phe-Gly-Ser-Gly] und cyclo-[Pro-Ser-Gly-Phe-Gly] European Journal of Organic Chemistry. 1983: 316-329. DOI: 10.1002/Jlac.198319830216  0.396
1983 Kessler H, Schuck R, Siegmeier R, Bats JW, Fuess H, Förster H. Peptidkonformationen, 22. Die Konformation von cyclo‐[Pro2‐(NB)Gly] im Kristall und in Lösung durch Röntgenstrukturanalyse und ein‐ und zweidimensionale NMR‐Spektroskopie European Journal of Organic Chemistry. 1983: 231-247. DOI: 10.1002/Jlac.198319830208  0.368
1983 Kessler H, Bernd M, Kogler H, Zarbock J, Soerensen OW, Bodenhausen G, Ernst RR. Peptide conformations. 28. Relayed heteronuclear correlation spectroscopy and conformational analysis of cyclic hexapeptides containing the active sequence of somatostatin Journal of the American Chemical Society. 105: 6944-6952. DOI: 10.1002/Chin.198408283  0.636
1983 Kessler H, Bermel W, Krack G, Bats JW, Fuess H, Hull WE. Peptide Conformations. 27. Cyclo(L‐Pro‐(Bzl)Gly‐D‐Pro). Synthesis And Conformation In The Crystal And In Solution Cheminform. 14. DOI: 10.1002/Chin.198349064  0.34
1983 Kessler H, Schuck R, Siegmeier R, Bats JW, Fuess H, Foerster H+. Peptide Conformations. 22. The Conformation Of Cyclo(Pro2‐(Nb)Gly) In Crystal And Solution By X‐Ray Analysis And One‐ And Two‐Dimensional Nmr Spectroscopy Cheminform. 14. DOI: 10.1002/Chin.198318061  0.364
1983 Kessler H, Bermel W, Krack G, Bats JW, Fuess H, Hull WE. Peptidkonformationen, 27. cyclo‐[L‐Pro‐(Bzl)Gly‐D‐Pro]. Synthese und Konformation im Kristall und in Lösung Chemische Berichte. 116: 3164-3181. DOI: 10.1002/Cber.19831160915  0.376
1982 Kessler H, Bermel W, Friedrich A, Krack G, Hull WE. Peptide conformation. 17. cyclo-(L-Pro-L-Pro-D-Pro). Conformational analysis by 270- and 500-MHZ one- and two-dimensional proton NMR spectroscopy Journal of the American Chemical Society. 104: 6297-6304. DOI: 10.1021/Ja00387A025  0.358
1982 Kessler H, Hehlein W, Schuck R. Peptide conformations. 15. One- and two-dimensional proton, carbon-13 and nitrogen-15 NMR studies of cyclo(Pro-Phe-Gly-Phe-Gly)n (n = 1, 2): selective complexation of lithium ions (n = 1) and potassium ions (n = 2) Journal of the American Chemical Society. 104: 4534-4540. DOI: 10.1021/Ja00381A006  0.302
1982 Kessler H, Schuck R, Siegmeier R. Peptide conformation. 18. Analysis of the conformational equilibrium of cyclo[Pro-NBGly2] by means of two-dimensional NMR spectroscopy Journal of the American Chemical Society. 104: 4486-4487. DOI: 10.1021/Ja00380A030  0.385
1982 Kessler H, Eiermann V. Peptide conformation, 24 homo- and heteronuclear 2D NMR spectroscopy of cyclic pentapeptides containing the active sequenceof somatostatin Tetrahedron Letters. 23: 4689-4692. DOI: 10.1016/S0040-4039(00)85688-9  0.393
1982 Kessler H, Bernd M, Damm I. Peptide conformations, 23 NMR investigation of cyclic hexapeptides containing the active sequence of somatostatin☆ Tetrahedron Letters. 23: 4685-4688. DOI: 10.1016/S0040-4039(00)85687-7  0.402
1982 Kessler H, Schuck R, Siegmeier R. Peptide conformation. 18. Analysis of the conformational equilibrium of cyclo[Pro-NBGly2] by means of two-dimensional NMR spectroscopy Cheminform. 13. DOI: 10.1002/Chin.198246048  0.385
1982 Kessler H. Conformation and Biological Activity of Cyclic Peptides Angewandte Chemie. 21: 512-523. DOI: 10.1002/Anie.198205121  0.371
1981 Kessler H, Friedrich A, Hull WE. Peptide conformation. 12. Conformation of cyclo-(L-Pro3) in solution Journal of Organic Chemistry. 13: 3892-3895. DOI: 10.1021/Jo00332A026  0.343
1981 Kessler H, Hölzemann G. Peptidkonformationen, XIII. cyclo‐Enkephaline — Synthese und Konformationsstudien European Journal of Organic Chemistry. 1981: 2028-2044. DOI: 10.1002/Jlac.198119811111  0.381
1980 Kessler H, Kraemer P, Krack G. Peptide Conformation, Ix. Conformational Studies On Cyclotripeptides Containing N-Benzyl-Glycine Cheminform. 11. DOI: 10.1002/Chin.198040075  0.366
1980 Bats JW, Fuess H, Kessler H, Schuck R. tert‐Butoxycarbonyl‐L‐α‐phenylalanin. Kristallstruktur und Konformationsumwandlungen in Lösung Chemische Berichte. 113: 520-530. DOI: 10.1002/Cber.19801130210  0.315
1980 Kessler H, Ott W, Lindner HJ, Schnering HGV, Peters E, Peters K. Die Struktur des 2,6‐Diphenylhomotropilidens Chemische Berichte. 113: 90-103. DOI: 10.1002/Cber.19801130112  0.311
1980 Binsch G, Kessler H. The Kinetic and Mechanistic Evaluation of NMR Spectra. New analytical methods (18) Angewandte Chemie International Edition in English. 19: 411-428. DOI: 10.1002/Anie.198004113  0.309
1979 Bats JW, Friedrich A, Fuess H, Kessler H, Maestle W, Rothe M. Peptide Conformations. 6. The Boat Conformation Of Cyclo(L-Pro2-D-Pro) Cheminform. 10. DOI: 10.1002/Chin.197943070  0.354
1979 Feigel M, Kessler H. NMR-Spektroskopische Untersuchungen zur Kinetik und Thermodynamik reversibler Dissoziationsreaktionen, VII. Direkte Beobachtung der Ionisation und Ionenrekombination von Tritylchlorid in SO2 Chemische Berichte. 112: 3715-3722. DOI: 10.1002/Cber.19791121119  0.315
1979 Kessler H, Kondor P. Peptidkonformationen, VI. Festlegung von intramolekularen Wasserstoffbrücken in cyclo(‐Phe‐Gly‐Xxx‐Val‐Ala‐) durch 1H‐NMR‐Spektroskopie Chemische Berichte. 112: 3538-3551. DOI: 10.1002/Cber.19791121103  0.392
1978 Kessler H, Kondor P, Krack G, Kraemer P. Conformational Equilibrium In The Backbone Of Cyclic Tripeptides Journal of the American Chemical Society. 100: 2548-2550. DOI: 10.1021/Ja00476A048  0.334
1978 Bara YA, Friedrich A, Kessler H, Molter M. Conformation Of Peptides, Ii. Proton Nmr Investigation Of The Conformation Of Cyclo(-Phe3-Gly2-) Cheminform. 9. DOI: 10.1002/Chin.197821087  0.378
1978 Bicker R, Kessler H, Steigel A, Zimmermann G. 13C-NMR-Spektroskopie von Norbornanderivaten, II: Einfluß homokonjugativer Wechselwirkungen auf die Carbonylverschiebung in Norbornanonsystemen Chemische Berichte. 111: 3215-3221. DOI: 10.1002/Cber.19781110925  0.326
1978 Feigel M, Kessler H, Walter A. NMR-Spektroskopische Untersuchungen zur Kinetik und Thermodynamik reversibler Dissoziationsreaktionen, V. Das Gleichgewicht zwischen Kontaktionenpaaren des Tropyliumisothiocyanats und kovalentem 7-Isothiocyanatocycloheptatrien — 1H- und 13C-NMR-Messungen Chemische Berichte. 111: 2947-2959. DOI: 10.1002/Cber.19781110824  0.326
1978 Kessler H, Zimmermann G, Fietze H, Möhrle H. Nachweis innermolekularer Beweglichkeit durch NMR-Spektroskopie, XXX. Simultane Beobachtung dreier reversibler Austauschprozesse im Diphenylborinsäure-diethanolaminester — eine 1H- und 13C-DNMR-spektroskopische Untersuchung Chemische Berichte. 111: 2605-2614. DOI: 10.1002/Cber.19781110716  0.312
1978 Bara YA, Friedrich A, Kessler H, Molter M. Peptidkonformationen, II: 1H-NMR-Untersuchungen zur Konformation von cyclo(-Phe3Gly2-) Chemische Berichte. 111: 1045-1057. DOI: 10.1002/Cber.19781110324  0.369
1978 Bara YA, Friedrich A, Hehlein W, Kessler H, Kondor P, Molter M, Veith H. Synthese der cyclischen Pentapeptide aus L‐Phenylalanin und Glycin Chemische Berichte. 111: 1029-1044. DOI: 10.1002/Cber.19781110323  0.333
1975 Branik M, Kessler H. Konformation Geschuetzter Aminosaeuren 4. Mitt. Nmr- Und Ir-Untersuchungen Von Boc-Omega-Aminosaeuren Cheminform. 6. DOI: 10.1002/Chin.197541072  0.315
1975 Branik M, Kessler H. Zur Konformation geschützter Aminosäuren, III. NMR‐ und IR‐Untersuchungen von Boc‐L‐α‐Aminosäuren Chemische Berichte. 108: 2176-2188. DOI: 10.1002/Cber.19751080704  0.306
1974 Kessler H, Molter M. Anwendung Der Eu(Fod)3-Induzierten Verschiebung Zur Festlegung Des Komplexierungsortes Und Zur Signalzuordnung In (13)C-Nmr-Spektren Geschuetzter Dipeptide Cheminform. 5. DOI: 10.1002/Chin.197440084  0.305
1974 Kalinowski H, Kessler H. Korrelation Der (13)C-Nmr-Chemischen Verschiebungen Von Carbonyl- Und Thiocarbonyl-Gruppen Cheminform. 5. DOI: 10.1002/Chin.197411072  0.305
1974 Kessler H, Molter M. Konformation Geschuetzter Aminosaeuren 2. Mitt. Dynamische Nmr-Messungen An Boc-Aminosaeureestern Unter Verwendung Von Lanthanoiden-Verschiebungsreagenzien Cheminform. 5. DOI: 10.1002/Chin.197406083  0.346
1974 Kalinowski H, Kessler H. Korrelation der 13C-NMR-chemischen Verschiebungen von Carbonyl- und Thiocarbonyl-Gruppen† Angewandte Chemie. 86: 43-45. DOI: 10.1002/Ange.19740860108  0.305
1973 Kessler H, Molter M. Dynamic NMR Measurements of Boc-amino Esters with Application of Lanthanoid Shift Reagents†‡ Angewandte Chemie. 12: 1011-1012. DOI: 10.1002/Anie.197310111  0.303
1970 Kessler H, Leibfritz D. Nachweis innermolekularer Beweglichkeit durch NMR‐Spektroskopie, XVIII1) Vergleich der Inversionsgeschwindigkeiten am doppelt gebundenen Stickstoff bei Guanidinen und Imidazolidiniminen European Journal of Organic Chemistry. 737: 53-60. DOI: 10.1002/Jlac.19707370106  0.307
1970 Kessler H, Leibfritz D. Nachweis Innermolekularer Beweglichkeit Durch Nmr-Spektroskopie 18. Mitt. Vergleich Der Inversionsgeschwindigkeiten Am Doppelt Gebundenen Stickstoff Bei Guanidinen Und Imidazolidiniminen Cheminform. 1. DOI: 10.1002/Chin.197045152  0.344
1970 Kessler H. Detection of Hindered Rotation and Inversion by NMR Spectroscopy Angewandte Chemie. 9: 219-235. DOI: 10.1002/Anie.197002191  0.301
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