Claudio Battilocchio - Publications

2012- Department of Chemistry University of Cambridge, Cambridge, England, United Kingdom 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nicholson W, Barreteau F, Leitch J, Payne R, Priestley I, Godineau E, Battilocchio C, Browne DL. Direct Amidation of Esters via Ball Milling. Angewandte Chemie (International Ed. in English). PMID 34357668 DOI: 10.1002/anie.202106412  0.62
2020 Lehmann M, Scarborough CC, Godineau E, Battilocchio C. An Electrochemical Flow-Through Cell for Rapid Reactions Industrial & Engineering Chemistry Research. 59: 7321-7326. DOI: 10.1021/Acs.Iecr.0C00431  0.335
2019 Godineau E, Battilocchio C, Lal M. Building up a Continuous Flow Platform as an Enabler to the Preparation of Intermediates on Kilogram Scale. Chimia. 73: 828-831. PMID 31645244 DOI: 10.2533/Chimia.2019.828  0.387
2019 Labes R, Mateos C, Battilocchio C, Chen Y, Dingwall P, Cumming GR, Rincón JA, Nieves-Remacha MJ, Ley SV. Fast continuous alcohol amination employing a hydrogen borrowing protocol Green Chemistry. 21: 59-63. DOI: 10.1039/C8Gc03328E  0.446
2018 Lesieur M, Battilocchio C, Labes R, Jacq J, Genicot C, Ley SV, Pasau P. Direct Oxidation of Csp -H bonds using in Situ Generated Trifluoromethylated Dioxirane in Flow. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30485562 DOI: 10.1002/Chem.201805657  0.463
2018 Ou X, Labes R, Battilocchio C, Ley SV. Preparation of homoallylic amines via a three-component coupling process. Organic & Biomolecular Chemistry. PMID 30183047 DOI: 10.1039/C8Ob01831F  0.507
2018 Ritson DJ, Battilocchio C, Ley SV, Sutherland JD. Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry. Nature Communications. 9: 1821. PMID 29739945 DOI: 10.1038/S41467-018-04147-2  0.489
2018 Scott CD, Labes R, Depardieu M, Battilocchio C, Davidson MG, Ley SV, Wilson CC, Robertson K. Integrated plug flow synthesis and crystallisation of pyrazinamide Reaction Chemistry & Engineering. 3: 631-634. DOI: 10.1039/C8Re00087E  0.5
2018 Godineau E, Battilocchio C, Lehmann M, Ley SV, Labes R, Birnoschi L, Subramanian S, Prasanna CS, Gorde A, Kalbagh M, Khade V, Scherrer A, O’Sullivan AC. A Convergent Continuous Multistep Process for the Preparation of C4-Oxime-Substituted Thiazoles Organic Process Research & Development. 22: 955-962. DOI: 10.1021/Acs.Oprd.8B00095  0.486
2017 Bomio C, Kabeshov MA, Lit AR, Lau SH, Ehlert J, Battilocchio C, Ley SV. Unveiling the role of boroxines in metal-free carbon-carbon homologations using diazo compounds and boronic acids. Chemical Science. 8: 6071-6075. PMID 29619197 DOI: 10.1039/C7Sc02264F  0.736
2017 Greb A, Poh JS, Greed S, Battilocchio C, Pasau P, Blakemore DC, Ley SV. A New Versatile Route to Unstable Diazo Compounds via Oxadiazolines and Use In Aryl-Alkyl Cross-Coupling Reactions. Angewandte Chemie (International Ed. in English). PMID 29088512 DOI: 10.1002/Anie.201710445  0.521
2017 Poh JS, Makai S, von Keutz T, Tran DN, Battilocchio C, Pasau P, Ley SV. Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines. Angewandte Chemie (International Ed. in English). PMID 28075518 DOI: 10.1002/Anie.201611067  0.546
2017 Ley S, Pastre J, Forni J, Lau S, Poh J, Battilocchio C. Diastereoselective Synthesis of Functionalized Indolines Using in situ Generated Allyl Boronic Species Synlett. 29: 825-829. DOI: 10.1055/S-0036-1589164  0.501
2017 Labes R, González-Calderón D, Battilocchio C, Mateos C, Cumming G, de Frutos O, Rincón J, Ley S. Rapid Continuous Ruthenium-Catalysed Transfer Hydrogenation of Aromatic Nitriles to Primary Amines Synlett. 28: 2855-2858. DOI: 10.1055/S-0036-1589096  0.484
2017 Battilocchio C, Iannucci G, Wang S, Godineau E, Kolleth A, De Mesmaeker A, Ley SV. Flow synthesis of cyclobutanones via [2 + 2] cycloaddition of keteneiminium salts and ethylene gas Reaction Chemistry & Engineering. 2: 295-298. DOI: 10.1039/C7Re00020K  0.512
2017 Battilocchio C, Bosica F, Rowe SM, Abreu BL, Godineau E, Lehmann M, Ley SV. Continuous Preparation and Use of Dibromoformaldoxime as a Reactive Intermediate for the Synthesis of 3-Bromoisoxazolines Organic Process Research & Development. 21: 1588-1594. DOI: 10.1021/Acs.Oprd.7B00229  0.499
2017 Labes R, Battilocchio C, Mateos C, Cumming GR, de Frutos O, Rincón JA, Binder K, Ley SV. Chemoselective Continuous Ru-Catalyzed Hydrogen-Transfer Oppenauer-Type Oxidation of Secondary Alcohols Organic Process Research & Development. 21: 1419-1422. DOI: 10.1021/Acs.Oprd.7B00190  0.457
2016 Poh JS, Lau SH, Dykes IG, Tran DN, Battilocchio C, Ley SV. A multicomponent approach for the preparation of homoallylic alcohols. Chemical Science. 7: 6803-6807. PMID 28042466 DOI: 10.1039/C6Sc02581A  0.742
2016 Lima F, Kabeshov MA, Tran DN, Battilocchio C, Sedelmeier J, Sedelmeier G, Schenkel B, Ley SV. Visible Light Activation of Boronic Esters Enables Efficient Photoredox C(sp(2) )-C(sp(3) ) Cross-Couplings in Flow. Angewandte Chemie (International Ed. in English). PMID 27709749 DOI: 10.1002/Anie.201605548  0.64
2016 Movsisyan M, Delbeke EI, Berton JK, Battilocchio C, Ley SV, Stevens CV. Taming hazardous chemistry by continuous flow technology. Chemical Society Reviews. PMID 27453961 DOI: 10.1039/C5Cs00902B  0.524
2016 Fitzpatrick DE, Battilocchio C, Ley SV. Enabling Technologies for the Future of Chemical Synthesis. Acs Central Science. 2: 131-8. PMID 27163040 DOI: 10.1021/Acscentsci.6B00015  0.716
2016 Battilocchio C, Feist F, Hafner A, Simon M, Tran DN, Allwood DM, Blakemore DC, Ley SV. Iterative reactions of transient boronic acids enable sequential C-C bond formation. Nature Chemistry. 8: 360-7. PMID 27001732 DOI: 10.1038/Nchem.2439  0.77
2016 Ouchi T, Mutton RJ, Rojas V, Fitzpatrick DE, Cork DG, Battilocchio C, Ley SV. Solvent-Free Continuous Operations Using Small Footprint Reactors: A Key Approach for Process Intensification Acs Sustainable Chemistry and Engineering. 4: 1912-1916. DOI: 10.1021/Acssuschemeng.6B00287  0.744
2015 Tran DN, Battilocchio C, Lou SB, Hawkins JM, Ley SV. Flow chemistry as a discovery tool to access sp-spcross-coupling reactionsdiazo compounds. Chemical Science. 6: 1120-1125. PMID 29560199 DOI: 10.1039/C4Sc03072A  0.527
2015 Briggs ME, Slater AG, Lunt N, Jiang S, Little MA, Greenaway RL, Hasell T, Battilocchio C, Ley SV, Cooper AI. Dynamic flow synthesis of porous organic cages. Chemical Communications (Cambridge, England). PMID 26463103 DOI: 10.1039/C5Cc07447A  0.508
2015 Ley SV, Fitzpatrick DE, Myers RM, Battilocchio C, Ingham RJ. Machine-Assisted Organic Synthesis. Angewandte Chemie (International Ed. in English). 54: 10122-36. PMID 26193360 DOI: 10.1002/Anie.201501618  0.754
2015 Lau SH, Galván A, Merchant RR, Battilocchio C, Souto JA, Berry MB, Ley SV. Machines vs Malaria: A Flow-Based Preparation of the Drug Candidate OZ439. Organic Letters. 17: 3218-21. PMID 26079282 DOI: 10.1021/Acs.Orglett.5B01307  0.742
2015 Poh JS, Tran DN, Battilocchio C, Hawkins JM, Ley SV. A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo Compounds. Angewandte Chemie (International Ed. in English). 54: 7920-3. PMID 26013774 DOI: 10.1002/Anie.201501538  0.529
2015 Rouquet G, Moore DE, Spain M, Allwood DM, Battilocchio C, Blakemore DC, Fish PV, Jenkinson S, Jessiman AS, Ley SV, McMurray G, Storer RI. Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists. Acs Medicinal Chemistry Letters. 6: 329-33. PMID 25815155 DOI: 10.1021/Ml500507V  0.751
2015 Roda NM, Tran DN, Battilocchio C, Labes R, Ingham RJ, Hawkins JM, Ley SV. Cyclopropanation using flow-generated diazo compounds. Organic & Biomolecular Chemistry. 13: 2550-4. PMID 25600950 DOI: 10.1039/C5Ob00019J  0.499
2015 Ingham RJ, Battilocchio C, Fitzpatrick DE, Sliwinski E, Hawkins JM, Ley SV. A systems approach towards an intelligent and self-controlling platform for integrated continuous reaction sequences. Angewandte Chemie (International Ed. in English). 54: 144-8. PMID 25377747 DOI: 10.1002/Anie.201409356  0.755
2015 Glöckner S, Tran DN, Ingham RJ, Fenner S, Wilson ZE, Battilocchio C, Ley SV. The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions. Organic & Biomolecular Chemistry. 13: 207-14. PMID 25370905 DOI: 10.1039/C4Ob02105C  0.503
2015 Tran DN, Battilocchio C, Lou SB, Hawkins JM, Ley SV. Flow chemistry as a discovery tool to access sp2-sp3 cross-coupling reactions via diazo compounds Chemical Science. 6: 1120-1125. DOI: 10.1039/c4sc03072a  0.418
2015 Fitzpatrick DE, Battilocchio C, Ley SV. A Novel Internet-Based Reaction Monitoring, Control and Autonomous Self-Optimization Platform for Chemical Synthesis Organic Process Research & Development. 20: 386-394. DOI: 10.1021/Acs.Oprd.5B00313  0.726
2015 Ley SV, Fitzpatrick DE, Myers RM, Battilocchio C, Ingham RJ. Maschinengestützte organische Synthese Angewandte Chemie. 127: 10260-10275. DOI: 10.1002/Ange.201501618  0.745
2014 Ingham RJ, Battilocchio C, Hawkins JM, Ley SV. Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide. Beilstein Journal of Organic Chemistry. 10: 641-52. PMID 24778715 DOI: 10.3762/Bjoc.10.56  0.492
2014 Battilocchio C, Hawkins JM, Ley SV. Mild and selective heterogeneous catalytic hydration of nitriles to amides by flowing through manganese dioxide. Organic Letters. 16: 1060-3. PMID 24495110 DOI: 10.1021/Ol403591C  0.534
2014 Ouchi T, Battilocchio C, Hawkins JM, Ley SV. Process intensification for the continuous flow hydrogenation of ethyl nicotinate Organic Process Research and Development. 18: 1560-1566. DOI: 10.1021/Op500208J  0.452
2014 Battilocchio C, Bhawal BN, Chorghade R, Deadman BJ, Hawkins JM, Ley SV. Flow-based, cerium oxide enhanced, low-level palladium sonogashira and heck coupling reactions by perovskite catalysts Israel Journal of Chemistry. 54: 371-380. DOI: 10.1002/Ijch.201300049  0.499
2013 Battilocchio C, Guetzoyan L, Cervetto C, Di Cesare Mannelli L, Frattaroli D, Baxendale IR, Maura G, Rossi A, Sautebin L, Biava M, Ghelardini C, Marcoli M, Ley SV. Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release. Acs Medicinal Chemistry Letters. 4: 704-9. PMID 24900736 DOI: 10.1021/Ml400079H  0.455
2013 Chorghade R, Battilocchio C, Hawkins JM, Ley SV. Sustainable flow Oppenauer oxidation of secondary benzylic alcohols with a heterogeneous zirconia catalyst. Organic Letters. 15: 5698-701. PMID 24161124 DOI: 10.1021/Ol4027107  0.446
2013 Battilocchio C, Deadman BJ, Nikbin N, Kitching MO, Baxendale IR, Ley SV. A machine-assisted flow synthesis of SR48692: a probe for the investigation of neurotensin receptor-1. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 7917-30. PMID 23592596 DOI: 10.1002/Chem.201300696  0.723
2013 Battilocchio C, Hawkins JM, Ley SV. A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia. Organic Letters. 15: 2278-81. PMID 23590578 DOI: 10.1021/Ol400856G  0.508
2013 Deadman BJ, Battilocchio C, Sliwinski E, Ley SV. A prototype device for evaporation in batch and flow chemical processes Green Chemistry. 15: 2050-2055. DOI: 10.1039/C3Gc40967H  0.757
2012 Battilocchio C, Baumann M, Baxendale IR, Biava M, Kitching MO, Ley SV, Martin RE, Ohnmacht SA, Tappin NDC. Scale-up of flow-assisted synthesis of C 2-symmetric chiral PyBox ligands Synthesis. 44: 635-647. DOI: 10.1055/S-0031-1289676  0.724
2012 Battilocchio C, Baxendale IR, Biava M, Kitching MO, Ley SV. A flow-based synthesis of 2-aminoadamantane-2-carboxylic acid Organic Process Research and Development. 16: 798-810. DOI: 10.1021/Op300084Z  0.748
2011 Biava M, Porretta GC, Poce G, Battilocchio C, Alfonso S, de Logu A, Manetti F, Botta M. Developing pyrrole-derived antimycobacterial agents: a rational lead optimization approach. Chemmedchem. 6: 593-9. PMID 21341373 DOI: 10.1002/Cmdc.201000526  0.302
2010 Biava M, Porretta GC, Poce G, Battilocchio C, Manetti F, Botta M, Forli S, Sautebin L, Rossi A, Pergola C, Ghelardini C, Galeotti N, Makovec F, Giordani A, Anzellotti P, et al. Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation. Journal of Medicinal Chemistry. 53: 723-33. PMID 19957931 DOI: 10.1021/Jm901269Y  0.306
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