Claudio Battilocchio - Publications

Affiliations: 
2012- Department of Chemistry University of Cambridge, Cambridge, England, United Kingdom 

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nicholson W, Barreteau F, Leitch J, Payne R, Priestley I, Godineau E, Battilocchio C, Browne DL. Direct Amidation of Esters via Ball Milling. Angewandte Chemie (International Ed. in English). PMID 34357668 DOI: 10.1002/anie.202106412  0.52
2021 Martin B, Battilocchio C, Ladosz A. Introducing the Flow Chemistry Network. Chimia. 75: 340-341. PMID 33902807 DOI: 10.2533/chimia.2021.340  0.01
2019 Godineau E, Battilocchio C, Lal M. Building up a Continuous Flow Platform as an Enabler to the Preparation of Intermediates on Kilogram Scale. Chimia. 73: 828-831. PMID 31645244 DOI: 10.2533/Chimia.2019.828  0.52
2019 Battilocchio C, Godineau E. Editorial. Chimia. 73: 789. PMID 31645238  0.52
2018 Lesieur M, Battilocchio C, Labes R, Jacq J, Genicot C, Ley SV, Pasau P. Direct Oxidation of Csp -H bonds using in Situ Generated Trifluoromethylated Dioxirane in Flow. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30485562 DOI: 10.1002/Chem.201805657  1
2018 Ou X, Labes R, Battilocchio C, Ley SV. Preparation of homoallylic amines via a three-component coupling process. Organic & Biomolecular Chemistry. PMID 30183047 DOI: 10.1039/C8Ob01831F  1
2018 Ritson DJ, Battilocchio C, Ley SV, Sutherland JD. Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry. Nature Communications. 9: 1821. PMID 29739945 DOI: 10.1038/S41467-018-04147-2  1
2017 Bomio C, Kabeshov MA, Lit AR, Lau SH, Ehlert J, Battilocchio C, Ley SV. Unveiling the role of boroxines in metal-free carbon-carbon homologations using diazo compounds and boronic acids. Chemical Science. 8: 6071-6075. PMID 29619197 DOI: 10.1039/C7Sc02264F  1
2017 Greb A, Poh JS, Greed S, Battilocchio C, Pasau P, Blakemore DC, Ley SV. A New Versatile Route to Unstable Diazo Compounds via Oxadiazolines and Use In Aryl-Alkyl Cross-Coupling Reactions. Angewandte Chemie (International Ed. in English). PMID 29088512 DOI: 10.1002/Anie.201710445  1
2017 Poh JS, Makai S, von Keutz T, Tran DN, Battilocchio C, Pasau P, Ley SV. Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines. Angewandte Chemie (International Ed. in English). PMID 28075518 DOI: 10.1002/Anie.201611067  1
2016 Poh JS, Lau SH, Dykes IG, Tran DN, Battilocchio C, Ley SV. A multicomponent approach for the preparation of homoallylic alcohols. Chemical Science. 7: 6803-6807. PMID 28042466 DOI: 10.1039/C6Sc02581A  1
2016 Lima F, Kabeshov MA, Tran DN, Battilocchio C, Sedelmeier J, Sedelmeier G, Schenkel B, Ley SV. Visible Light Activation of Boronic Esters Enables Efficient Photoredox C(sp(2) )-C(sp(3) ) Cross-Couplings in Flow. Angewandte Chemie (International Ed. in English). PMID 27709749 DOI: 10.1002/Anie.201605548  1
2016 Movsisyan M, Delbeke EI, Berton JK, Battilocchio C, Ley SV, Stevens CV. Taming hazardous chemistry by continuous flow technology. Chemical Society Reviews. PMID 27453961 DOI: 10.1039/C5Cs00902B  1
2016 Fitzpatrick DE, Battilocchio C, Ley SV. Enabling Technologies for the Future of Chemical Synthesis. Acs Central Science. 2: 131-8. PMID 27163040 DOI: 10.1021/Acscentsci.6B00015  1
2016 Battilocchio C, Feist F, Hafner A, Simon M, Tran DN, Allwood DM, Blakemore DC, Ley SV. Iterative reactions of transient boronic acids enable sequential C-C bond formation. Nature Chemistry. 8: 360-7. PMID 27001732 DOI: 10.1038/Nchem.2439  1
2016 Ouchi T, Mutton RJ, Rojas V, Fitzpatrick DE, Cork DG, Battilocchio C, Ley SV. Solvent-Free Continuous Operations Using Small Footprint Reactors: A Key Approach for Process Intensification Acs Sustainable Chemistry and Engineering. 4: 1912-1916. DOI: 10.1021/Acssuschemeng.6B00287  1
2015 Tran DN, Battilocchio C, Lou SB, Hawkins JM, Ley SV. Flow chemistry as a discovery tool to access sp-spcross-coupling reactionsdiazo compounds. Chemical Science. 6: 1120-1125. PMID 29560199 DOI: 10.1039/C4Sc03072A  1
2015 Briggs ME, Slater AG, Lunt N, Jiang S, Little MA, Greenaway RL, Hasell T, Battilocchio C, Ley SV, Cooper AI. Dynamic flow synthesis of porous organic cages. Chemical Communications (Cambridge, England). PMID 26463103 DOI: 10.1039/C5Cc07447A  1
2015 Ley SV, Fitzpatrick DE, Myers RM, Battilocchio C, Ingham RJ. Machine-Assisted Organic Synthesis. Angewandte Chemie (International Ed. in English). 54: 10122-36. PMID 26193360 DOI: 10.1002/Anie.201501618  1
2015 Lau SH, Galván A, Merchant RR, Battilocchio C, Souto JA, Berry MB, Ley SV. Machines vs Malaria: A Flow-Based Preparation of the Drug Candidate OZ439. Organic Letters. 17: 3218-21. PMID 26079282 DOI: 10.1021/Acs.Orglett.5B01307  1
2015 Poh JS, Tran DN, Battilocchio C, Hawkins JM, Ley SV. A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo Compounds. Angewandte Chemie (International Ed. in English). 54: 7920-3. PMID 26013774 DOI: 10.1002/Anie.201501538  1
2015 Rouquet G, Moore DE, Spain M, Allwood DM, Battilocchio C, Blakemore DC, Fish PV, Jenkinson S, Jessiman AS, Ley SV, McMurray G, Storer RI. Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists. Acs Medicinal Chemistry Letters. 6: 329-33. PMID 25815155 DOI: 10.1021/Ml500507V  1
2015 Roda NM, Tran DN, Battilocchio C, Labes R, Ingham RJ, Hawkins JM, Ley SV. Cyclopropanation using flow-generated diazo compounds. Organic & Biomolecular Chemistry. 13: 2550-4. PMID 25600950 DOI: 10.1039/C5Ob00019J  1
2015 Ingham RJ, Battilocchio C, Fitzpatrick DE, Sliwinski E, Hawkins JM, Ley SV. A systems approach towards an intelligent and self-controlling platform for integrated continuous reaction sequences. Angewandte Chemie (International Ed. in English). 54: 144-8. PMID 25377747 DOI: 10.1002/Anie.201409356  1
2015 Glöckner S, Tran DN, Ingham RJ, Fenner S, Wilson ZE, Battilocchio C, Ley SV. The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions. Organic & Biomolecular Chemistry. 13: 207-14. PMID 25370905 DOI: 10.1039/C4Ob02105C  1
2015 Tran DN, Battilocchio C, Lou SB, Hawkins JM, Ley SV. Flow chemistry as a discovery tool to access sp2-sp3 cross-coupling reactions via diazo compounds Chemical Science. 6: 1120-1125. DOI: 10.1039/c4sc03072a  1
2014 Ingham RJ, Battilocchio C, Hawkins JM, Ley SV. Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide. Beilstein Journal of Organic Chemistry. 10: 641-52. PMID 24778715 DOI: 10.3762/Bjoc.10.56  1
2014 Battilocchio C, Hawkins JM, Ley SV. Mild and selective heterogeneous catalytic hydration of nitriles to amides by flowing through manganese dioxide. Organic Letters. 16: 1060-3. PMID 24495110 DOI: 10.1021/Ol403591C  1
2014 Biava M, Battilocchio C, Poce G, Alfonso S, Consalvi S, Di Capua A, Calderone V, Martelli A, Testai L, Sautebin L, Rossi A, Ghelardini C, Di Cesare Mannelli L, Giordani A, Persiani S, et al. Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors. Bioorganic & Medicinal Chemistry. 22: 772-86. PMID 24373735 DOI: 10.1016/J.Bmc.2013.12.008  1
2014 Ouchi T, Battilocchio C, Hawkins JM, Ley SV. Process intensification for the continuous flow hydrogenation of ethyl nicotinate Organic Process Research and Development. 18: 1560-1566. DOI: 10.1021/Op500208J  1
2014 Battilocchio C, Bhawal BN, Chorghade R, Deadman BJ, Hawkins JM, Ley SV. Flow-based, cerium oxide enhanced, low-level palladium sonogashira and heck coupling reactions by perovskite catalysts Israel Journal of Chemistry. 54: 371-380. DOI: 10.1002/Ijch.201300049  1
2013 Battilocchio C, Guetzoyan L, Cervetto C, Di Cesare Mannelli L, Frattaroli D, Baxendale IR, Maura G, Rossi A, Sautebin L, Biava M, Ghelardini C, Marcoli M, Ley SV. Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release. Acs Medicinal Chemistry Letters. 4: 704-9. PMID 24900736 DOI: 10.1021/Ml400079H  1
2013 Chorghade R, Battilocchio C, Hawkins JM, Ley SV. Sustainable flow Oppenauer oxidation of secondary benzylic alcohols with a heterogeneous zirconia catalyst. Organic Letters. 15: 5698-701. PMID 24161124 DOI: 10.1021/Ol4027107  1
2013 Battilocchio C, Poce G, Alfonso S, Porretta GC, Consalvi S, Sautebin L, Pace S, Rossi A, Ghelardini C, Di Cesare Mannelli L, Schenone S, Giordani A, Di Francesco L, Patrignani P, Biava M. A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity. Bioorganic & Medicinal Chemistry. 21: 3695-701. PMID 23680444 DOI: 10.1016/J.Bmc.2013.04.031  1
2013 Battilocchio C, Deadman BJ, Nikbin N, Kitching MO, Baxendale IR, Ley SV. A machine-assisted flow synthesis of SR48692: a probe for the investigation of neurotensin receptor-1. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 7917-30. PMID 23592596 DOI: 10.1002/Chem.201300696  1
2013 Battilocchio C, Hawkins JM, Ley SV. A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia. Organic Letters. 15: 2278-81. PMID 23590578 DOI: 10.1021/Ol400856G  1
2013 Deadman BJ, Battilocchio C, Sliwinski E, Ley SV. A prototype device for evaporation in batch and flow chemical processes Green Chemistry. 15: 2050-2055. DOI: 10.1039/C3Gc40967H  1
2012 Biava M, Battilocchio C, Poce G, Alfonso S, Consalvi S, Porretta GC, Schenone S, Calderone V, Martelli A, Testai L, Ghelardini C, Di Cesare Mannelli L, Sautebin L, Rossi A, Giordani A, et al. Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme. European Journal of Medicinal Chemistry. 58: 287-98. PMID 23131542 DOI: 10.1016/J.Ejmech.2012.10.014  1
2012 La Rosa V, Poce G, Canseco JO, Buroni S, Pasca MR, Biava M, Raju RM, Porretta GC, Alfonso S, Battilocchio C, Javid B, Sorrentino F, Ioerger TR, Sacchettini JC, Manetti F, et al. MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212. Antimicrobial Agents and Chemotherapy. 56: 324-31. PMID 22024828 DOI: 10.1128/Aac.05270-11  1
2012 Battilocchio C, Baumann M, Baxendale IR, Biava M, Kitching MO, Ley SV, Martin RE, Ohnmacht SA, Tappin NDC. Scale-up of flow-assisted synthesis of C 2-symmetric chiral PyBox ligands Synthesis. 44: 635-647. DOI: 10.1055/S-0031-1289676  1
2012 Battilocchio C, Baxendale IR, Biava M, Kitching MO, Ley SV. A flow-based synthesis of 2-aminoadamantane-2-carboxylic acid Organic Process Research and Development. 16: 798-810. DOI: 10.1021/Op300084Z  1
2011 Biava M, Porretta GC, Poce G, Battilocchio C, Alfonso S, Rovini M, Valenti S, Giorgi G, Calderone V, Martelli A, Testai L, Sautebin L, Rossi A, Papa G, Ghelardini C, et al. Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties. Journal of Medicinal Chemistry. 54: 7759-71. PMID 21992176 DOI: 10.1021/jm200715n  1
2011 Biava M, Porretta GC, Poce G, Battilocchio C, Alfonso S, de Logu A, Manetti F, Botta M. Developing pyrrole-derived antimycobacterial agents: a rational lead optimization approach. Chemmedchem. 6: 593-9. PMID 21341373 DOI: 10.1002/Cmdc.201000526  1
2010 Biava M, Porretta GC, Poce G, Battilocchio C, Alfonso S, De Logu A, Serra N, Manetti F, Botta M. Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin. Bioorganic & Medicinal Chemistry. 18: 8076-84. PMID 20934344 DOI: 10.1016/J.Bmc.2010.09.006  1
2010 Biava M, Porretta GC, Poce G, Battilocchio C, Manetti F, Botta M, Forli S, Sautebin L, Rossi A, Pergola C, Ghelardini C, Galeotti N, Makovec F, Giordani A, Anzellotti P, et al. Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation. Journal of Medicinal Chemistry. 53: 723-33. PMID 19957931 DOI: 10.1021/Jm901269Y  1
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