Clara Abraham - Publications

Affiliations: 
Yale School of Medicine Yale University, New Haven, CT 
Area:
Biomedical Engineering, Immunology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Verstockt B, Salas A, Sands BE, Abraham C, Leibovitzh H, Neurath MF, Vande Casteele N. IL-12 and IL-23 pathway inhibition in inflammatory bowel disease. Nature Reviews. Gastroenterology & Hepatology. PMID 37069321 DOI: 10.1038/s41575-023-00768-1  0.303
2022 Abraham C, Abreu MT, Turner JR. Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease. Gastroenterology. PMID 35149024 DOI: 10.1053/j.gastro.2021.12.288  0.34
2021 Ranjan K, Hedl M, Sinha S, Zhang X, Abraham C. Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. The Journal of Clinical Investigation. 131. PMID 34623328 DOI: 10.1172/JCI145472  0.322
2021 Ranjan K, Hedl M, Abraham C. The E3 ubiquitin ligase RNF186 and risk variants regulate innate receptor-induced outcomes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34353900 DOI: 10.1073/pnas.2013500118  0.335
2020 Sun R, Hedl M, Abraham C. TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and these are Modulated by TNFSF15 Disease-Risk Variants. Cellular and Molecular Gastroenterology and Hepatology. PMID 32827707 DOI: 10.1016/J.Jcmgh.2020.08.003  0.413
2020 Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C. Myeloid Cell Expression of LACC1 is Required for Bacterial Clearance and Control of Intestinal Inflammation. Gastroenterology. PMID 32693188 DOI: 10.1053/J.Gastro.2020.07.024  0.445
2020 Yan J, Hedl M, Abraham C. Myeloid Cell-Intrinsic IRF5 Promotes T Cell Responses through Multiple Distinct Checkpoints In Vivo, and Immune-Mediated Disease Risk Variants Modulate These Myeloid Cell Functions. Journal of Immunology (Baltimore, Md. : 1950). PMID 32690658 DOI: 10.4049/Jimmunol.1900743  0.492
2020 Hedl M, Sun R, Abraham C. Disease Risk-Associated Genetic Variants in and Function in a Complementary Manner to Increase Pattern-Recognition Receptor-Induced Outcomes in Human Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 32661180 DOI: 10.4049/Jimmunol.1901112  0.512
2020 Yan J, Pandey SP, Barnes BJ, Turner JR, Abraham C. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation. Cell Reports. 31: 107820. PMID 32610123 DOI: 10.1016/J.Celrep.2020.107820  0.492
2020 Sun R, Abraham C. IL23 promotes antimicrobial pathways in human macrophages which are reduced with the IBD-protective IL23R R381Q variant. Cellular and Molecular Gastroenterology and Hepatology. PMID 32474165 DOI: 10.1016/J.Jcmgh.2020.05.007  0.429
2019 Huang C, Hedl M, Ranjan K, Abraham C. LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes. Cell Reports. 29: 4525-4539.e4. PMID 31875558 DOI: 10.1016/J.Celrep.2019.11.105  0.335
2019 Hedl M, Sun R, Huang C, Abraham C. STAT3 and STAT5 Signaling Thresholds Determine Distinct Regulation for Innate Receptor-Induced Inflammatory Cytokines, and / Disease Variants Modulate These Outcomes. Journal of Immunology (Baltimore, Md. : 1950). PMID 31732533 DOI: 10.4049/Jimmunol.1900031  0.508
2019 Pandey SP, Yan J, Turner JR, Abraham C. Correction to: Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens. Mucosal Immunology. PMID 31182816 DOI: 10.1038/S41385-019-0179-8  0.302
2019 Sun R, Hedl M, Abraham C. IL23 induces IL23R recycling and amplifies innate receptor-induced signalling and cytokines in human macrophages, and the IBD-protective IL23R R381Q variant modulates these outcomes. Gut. PMID 31097538 DOI: 10.1136/Gutjnl-2018-316830  0.452
2019 Pandey SP, Yan J, Turner JR, Abraham C. Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens. Mucosal Immunology. PMID 31053739 DOI: 10.1038/S41385-019-0165-1  0.444
2019 Sun R, Hedl M, Abraham C. Twist1 and Twist2 Induce Human Macrophage Memory upon Chronic Innate Receptor Treatment by HDAC-Mediated Deacetylation of Cytokine Promoters. Journal of Immunology (Baltimore, Md. : 1950). PMID 31028123 DOI: 10.4049/Jimmunol.1800757  0.392
2019 Gettler K, Giri M, Kenigsberg E, Martin J, Chuang LS, Hsu NY, Denson LA, Hyams JS, Griffiths A, Noe JD, Crandall WV, Mack DR, Kellermayer R, Abraham C, Hoffman G, et al. Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets. Genes and Immunity. PMID 30692607 DOI: 10.1038/S41435-019-0059-Y  0.338
2018 Hedl M, Yan J, Witt H, Abraham C. IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and Immune-Mediated Disease Risk Variants Modulate This Outcome. Journal of Immunology (Baltimore, Md. : 1950). PMID 30593537 DOI: 10.4049/Jimmunol.1800226  0.431
2018 Luong PH, Hedl M, Yan J, Zuo T, Fu TM, Jiang X, Thiagarajah JR, Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. Elife. 7. PMID 30355448 DOI: 10.7554/Elife.38539  0.442
2018 Luong P, Hedl M, Yan J, Zuo T, Fu T, Jiang X, Thiagarajah JR, Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI. Author response: INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling Elife. DOI: 10.7554/Elife.38539.018  0.316
2017 Bist P, Cheong WS, Ng A, Dikshit N, Kim BH, Pulloor NK, Khameneh HJ, Hedl M, Shenoy AR, Balamuralidhar V, Malik NBA, Hong M, Neutzner A, Chin KC, Kobayashi KS, ... ... Abraham C, et al. E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP. Nature Communications. 8: 15865. PMID 28656966 DOI: 10.1038/Ncomms15865  0.406
2017 Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H, Li HB, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, ... ... Abraham C, et al. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature. PMID 28636595 DOI: 10.1038/Nature22967  0.396
2017 Lahiri A, Hedl M, Yan J, Abraham C. Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes. Nature Communications. 8: 15614. PMID 28593945 DOI: 10.1038/Ncomms15614  0.452
2017 Yan J, Hedl M, Abraham C. An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes. The Journal of Clinical Investigation. PMID 28436939 DOI: 10.1172/Jci86282  0.475
2017 Schumacher MA, Hedl M, Abraham C, Bernard JK, Lozano PR, Hsieh JJ, Almohazey D, Bucar EB, Punit S, Dempsey PJ, Frey MR. ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation. Cell Death & Disease. 8: e2622. PMID 28230865 DOI: 10.1038/Cddis.2017.42  0.426
2016 Abraham C, Dulai PS, Vermeire S, Sandborn WJ. Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases. Gastroenterology. PMID 27780712 DOI: 10.1053/J.Gastro.2016.10.018  0.467
2016 Hedl M, Proctor DD, Abraham C. JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 27664279 DOI: 10.4049/Jimmunol.1600845  0.528
2016 Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV. ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. The Journal of Clinical Investigation. PMID 27617863 DOI: 10.1172/Jci85329  0.36
2016 Hedl M, Yan J, Abraham C. IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation. Cell Reports. PMID 27545875 DOI: 10.1016/J.Celrep.2016.07.060  0.45
2016 Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, ... ... Abraham C, et al. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nature Communications. 7: 12342. PMID 27503255 DOI: 10.1038/Ncomms12342  0.348
2016 Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, ... ... Abraham C, et al. A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF. Gastroenterology. PMID 27377463 DOI: 10.1053/J.Gastro.2016.06.045  0.355
2015 Lahiri A, Hedl M, Abraham C. MTMR3 risk allele enhances innate receptor-induced signaling and cytokines by decreasing autophagy and increasing caspase-1 activation. Proceedings of the National Academy of Sciences of the United States of America. 112: 10461-6. PMID 26240347 DOI: 10.1073/Pnas.1501752112  0.464
2015 Hedl M, Abraham C. A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion. Gut. PMID 26215868 DOI: 10.1136/Gutjnl-2014-308922  0.483
2015 Zheng S, Hedl M, Abraham C. Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators. Journal of Immunology (Baltimore, Md. : 1950). 195: 217-26. PMID 26019273 DOI: 10.4049/Jimmunol.1402808  0.419
2015 Wu X, Lahiri A, Sarin R, Abraham C. T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 194: 4122-9. PMID 25801431 DOI: 10.4049/Jimmunol.1401328  0.362
2015 Zheng S, Hedl M, Abraham C. TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 194: 1928-37. PMID 25567680 DOI: 10.4049/Jimmunol.1401933  0.462
2014 Hedl M, Abraham C. A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1. Proceedings of the National Academy of Sciences of the United States of America. 111: 13451-6. PMID 25197060 DOI: 10.1073/Pnas.1404178111  0.484
2014 Lahiri A, Abraham C. Activation of pattern recognition receptors up-regulates metallothioneins, thereby increasing intracellular accumulation of zinc, autophagy, and bacterial clearance by macrophages. Gastroenterology. 147: 835-46. PMID 24960189 DOI: 10.1053/J.Gastro.2014.06.024  0.419
2014 Hedl M, Zheng S, Abraham C. The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways. Journal of Immunology (Baltimore, Md. : 1950). 192: 5924-32. PMID 24842757 DOI: 10.4049/Jimmunol.1302727  0.43
2014 Hedl M, Lahiri A, Ning K, Cho JH, Abraham C. Pattern recognition receptor signaling in human dendritic cells is enhanced by ICOS ligand and modulated by the Crohn's disease ICOSLG risk allele. Immunity. 40: 734-46. PMID 24837102 DOI: 10.1016/J.Immuni.2014.04.011  0.452
2014 Wu X, Lahiri A, Haines GK, Flavell RA, Abraham C. NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury. Journal of Immunology (Baltimore, Md. : 1950). 192: 3409-18. PMID 24591373 DOI: 10.4049/Jimmunol.1302436  0.463
2013 Zheng S, Abraham C. NF-κB1 inhibits NOD2-induced cytokine secretion through ATF3-dependent mechanisms. Molecular and Cellular Biology. 33: 4857-71. PMID 24100018 DOI: 10.1128/Mcb.00797-13  0.42
2013 Zhang CK, Hewett J, Hemming J, Grant T, Zhao H, Abraham C, Oikonomou I, Kanakia M, Cho JH, Proctor DD. The influence of depression on quality of life in patients with inflammatory bowel disease. Inflammatory Bowel Diseases. 19: 1732-9. PMID 23669400 DOI: 10.1097/Mib.0B013E318281F395  0.308
2013 Su L, Nalle SC, Shen L, Turner ES, Singh G, Breskin LA, Khramtsova EA, Khramtsova G, Tsai PY, Fu YX, Abraham C, Turner JR. TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 145: 407-15. PMID 23619146 DOI: 10.1053/J.Gastro.2013.04.011  0.409
2013 Zhang W, Hui KY, Gusev A, Warner N, Ng SM, Ferguson J, Choi M, Burberry A, Abraham C, Mayer L, Desnick RJ, Cardinale CJ, Hakonarson H, Waterman M, Chowers Y, et al. Extended haplotype association study in Crohn's disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-κB pathway gene, HEATR3. Genes and Immunity. 14: 310-6. PMID 23615072 DOI: 10.1038/Gene.2013.19  0.356
2013 Shen H, Zhang W, Abraham C, Cho JH. Age and CD161 expression contribute to inter-individual variation in interleukin-23 response in CD8+ memory human T cells. Plos One. 8: e57746. PMID 23469228 DOI: 10.1371/Journal.Pone.0057746  0.406
2013 Hedl M, Abraham C. Negative regulation of human mononuclear phagocyte function Mucosal Immunology. 6: 205-223. PMID 23340822 DOI: 10.1038/Mi.2012.139  0.401
2013 Hedl M, Abraham C. NLRP1 and NLRP3 inflammasomes are essential for distinct outcomes of decreased cytokines but enhanced bacterial killing upon chronic Nod2 stimulation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G583-96. PMID 23287275 DOI: 10.1152/Ajpgi.00297.2012  0.451
2012 Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, ... ... Abraham C, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 491: 119-24. PMID 23128233 DOI: 10.1038/Nature11582  0.399
2012 Huber S, Gagliani N, Zenewicz LA, Huber FJ, Bosurgi L, Hu B, Hedl M, Zhang W, O'Connor W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Booth CJ, Cho JH, Ouyang W, ... Abraham C, et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature. 491: 259-63. PMID 23075849 DOI: 10.1038/Nature11535  0.396
2012 Hedl M, Abraham C. Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines. Gastroenterology. 143: 1530-43. PMID 22967725 DOI: 10.1053/J.Gastro.2012.08.048  0.459
2012 Sarin R, Abraham C. CD18 is required for optimal lymphopenia-induced proliferation of mouse T cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G851-60. PMID 22821945 DOI: 10.1152/Ajpgi.00520.2011  0.392
2012 Zhang W, Ferguson J, Ng SM, Hui K, Goh G, Lin A, Esplugues E, Flavell RA, Abraham C, Zhao H, Cho JH. Effector CD4+ T cell expression signatures and immune-mediated disease associated genes. Plos One. 7: e38510. PMID 22715389 DOI: 10.1371/Journal.Pone.0038510  0.442
2012 Hedl M, Abraham C. IRF5 risk polymorphisms contribute to interindividual variance in pattern recognition receptor-mediated cytokine secretion in human monocyte-derived cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 5348-56. PMID 22544929 DOI: 10.4049/Jimmunol.1103319  0.469
2012 Kenny EE, Pe'er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant SR, Bressman S, Burns ER, et al. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. Plos Genetics. 8: e1002559. PMID 22412388 DOI: 10.1371/Journal.Pgen.1002559  0.323
2011 Menard L, Saadoun D, Isnardi I, Ng YS, Meyers G, Massad C, Price C, Abraham C, Motaghedi R, Buckner JH, Gregersen PK, Meffre E. The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. The Journal of Clinical Investigation. 121: 3635-44. PMID 21804190 DOI: 10.1172/Jci45790  0.338
2011 Hedl M, Abraham C. Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages. The Journal of Biological Chemistry. 286: 26440-9. PMID 21659536 DOI: 10.1074/Jbc.M111.237495  0.405
2011 Sarin R, Wu X, Abraham C. Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses. Proceedings of the National Academy of Sciences of the United States of America. 108: 9560-5. PMID 21606346 DOI: 10.1073/Pnas.1017854108  0.469
2011 Abraham C, Medzhitov R. Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology. 140: 1729-37. PMID 21530739 DOI: 10.1053/J.Gastro.2011.02.012  0.396
2011 Hedl M, Abraham C. Secretory mediators regulate Nod2-induced tolerance in human macrophages. Gastroenterology. 140: 231-41. PMID 20854823 DOI: 10.1053/J.Gastro.2010.09.009  0.499
2010 Capurso NA, Look M, Jeanbart L, Nowyhed H, Abraham C, Craft J, Fahmy TM. Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells. Self/Nonself. 1: 335-340. PMID 21487509 DOI: 10.4161/self.1.4.13946  0.697
2010 Ballard D, Abraham C, Cho J, Zhao H. Pathway analysis comparison using Crohn's disease genome wide association studies. Bmc Medical Genomics. 3: 25. PMID 20584322 DOI: 10.1186/1755-8794-3-25  0.366
2010 Zenewicz LA, Abraham C, Flavell RA, Cho JH. Unraveling the genetics of autoimmunity. Cell. 140: 791-7. PMID 20303870 DOI: 10.1016/J.Cell.2010.03.003  0.36
2010 Hedl M, Phatak UP, Abraham C. W1795 An IL-1beta Autocrine Loop is Required for Optimal Acute NOD2 Responses Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63415-4  0.302
2010 Hedl M, Abraham C. Chronic Nod2 Stimulation Downregulates Bacteria-induced Inflammatory Cytokines, but Maintains Bacterial Killing Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.328  0.384
2009 Molinero LL, Yang J, Gajewski T, Abraham C, Farrar MA, Alegre ML. CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 6736-43. PMID 19454668 DOI: 10.4049/Jimmunol.0900498  0.43
2009 Abraham C, Cho J. Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflammatory Bowel Diseases. 15: 1090-100. PMID 19253307 DOI: 10.1002/Ibd.20894  0.511
2009 Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C, Turner JR. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology. 136: 551-63. PMID 19027740 DOI: 10.1053/J.Gastro.2008.10.081  0.42
2009 Abraham C, Cho JH. IL-23 and autoimmunity: new insights into the pathogenesis of inflammatory bowel disease. Annual Review of Medicine. 60: 97-110. PMID 18976050 DOI: 10.1146/Annurev.Med.60.051407.123757  0.517
2008 Molinero LL, Zhou P, Wang Y, Harlin H, Kee B, Abraham C, Alegre ML. Epidermal Langerhans cells promote skin allograft rejection in mice with NF-kappa B-impaired T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8: 21-31. PMID 18021281 DOI: 10.1111/J.1600-6143.2007.02038.X  0.321
2008 Hedl M, Abraham C. Sa.124. Nod2 Mediates Tolerance in Primary Human Cells Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.345  0.324
2007 Hedl M, Li J, Cho JH, Abraham C. Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proceedings of the National Academy of Sciences of the United States of America. 104: 19440-5. PMID 18032608 DOI: 10.1073/Pnas.0706097104  0.449
2007 Abraham C, Cho JH. Bugging of the intestinal mucosa. The New England Journal of Medicine. 357: 708-10. PMID 17699823 DOI: 10.1056/Nejmcibr073420  0.34
2007 Marski M, Ye AL, Abraham C. CD18 is required for intestinal T cell responses at multiple immune checkpoints. Journal of Immunology (Baltimore, Md. : 1950). 178: 2104-12. PMID 17277114 DOI: 10.4049/Jimmunol.178.4.2104  0.398
2007 Cho JH, Abraham C. Inflammatory bowel disease genetics: Nod2. Annual Review of Medicine. 58: 401-16. PMID 16987083 DOI: 10.1146/Annurev.Med.58.061705.145024  0.39
2006 Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (New York, N.Y.). 314: 1461-3. PMID 17068223 DOI: 10.1126/Science.1135245  0.422
2006 Wang F, Schwarz BT, Graham WV, Wang Y, Su L, Clayburgh DR, Abraham C, Turner JR. IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction. Gastroenterology. 131: 1153-63. PMID 17030185 DOI: 10.1053/J.Gastro.2006.08.022  0.419
2006 Abraham C, Cho JH. Functional consequences of NOD2 (CARD15) mutations. Inflammatory Bowel Diseases. 12: 641-50. PMID 16804402 DOI: 10.1097/01.Mib.0000225332.83861.5F  0.407
2005 Marski M, Kandula S, Turner JR, Abraham C. CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 7889-97. PMID 16339524 DOI: 10.4049/Jimmunol.175.12.7889  0.338
2005 Wang J, Anders RA, Wang Y, Turner JR, Abraham C, Pfeffer K, Fu YX. The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease. Journal of Immunology (Baltimore, Md. : 1950). 174: 8173-82. PMID 15944326 DOI: 10.4049/Jimmunol.174.12.8173  0.429
2004 Kandula S, Abraham C. LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 173: 4443-51. PMID 15383575 DOI: 10.4049/Jimmunol.173.7.4443  0.371
2004 Li J, Moran T, Swanson E, Julian C, Harris J, Bonen DK, Hedl M, Nicolae DL, Abraham C, Cho JH. Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations. Human Molecular Genetics. 13: 1715-25. PMID 15198989 DOI: 10.1093/Hmg/Ddh182  0.413
2001 Abraham C, Miller J. Molecular Mechanisms of IL-2 Gene Regulation Following Costimulation Through LFA-1 Journal of Immunology. 167: 5193-5201. PMID 11673532 DOI: 10.4049/Jimmunol.167.9.5193  0.417
2000 Abraham C, Miller J. Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1 Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)83455-1  0.344
1998 Abraham C, Scaglione–Sewell B, Skarosi SF, Qin W, Bissonnette M, Brasitus TA. Protein kinase C α modulates growth and differentiation in Caco-2 cells Gastroenterology. 114: 503-509. PMID 9496940 DOI: 10.1016/S0016-5085(98)70533-5  0.311
1998 Abraham C, Griffith J, Miller J. The role of LFA-1 in T cell activation cannot be compensated for by enhancing T cell receptor engagement Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)83734-7  0.336
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