Year |
Citation |
Score |
2023 |
Verstockt B, Salas A, Sands BE, Abraham C, Leibovitzh H, Neurath MF, Vande Casteele N. IL-12 and IL-23 pathway inhibition in inflammatory bowel disease. Nature Reviews. Gastroenterology & Hepatology. PMID 37069321 DOI: 10.1038/s41575-023-00768-1 |
0.303 |
|
2022 |
Abraham C, Abreu MT, Turner JR. Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease. Gastroenterology. PMID 35149024 DOI: 10.1053/j.gastro.2021.12.288 |
0.34 |
|
2021 |
Ranjan K, Hedl M, Sinha S, Zhang X, Abraham C. Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. The Journal of Clinical Investigation. 131. PMID 34623328 DOI: 10.1172/JCI145472 |
0.322 |
|
2021 |
Ranjan K, Hedl M, Abraham C. The E3 ubiquitin ligase RNF186 and risk variants regulate innate receptor-induced outcomes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34353900 DOI: 10.1073/pnas.2013500118 |
0.335 |
|
2020 |
Sun R, Hedl M, Abraham C. TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and these are Modulated by TNFSF15 Disease-Risk Variants. Cellular and Molecular Gastroenterology and Hepatology. PMID 32827707 DOI: 10.1016/J.Jcmgh.2020.08.003 |
0.413 |
|
2020 |
Kang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C. Myeloid Cell Expression of LACC1 is Required for Bacterial Clearance and Control of Intestinal Inflammation. Gastroenterology. PMID 32693188 DOI: 10.1053/J.Gastro.2020.07.024 |
0.445 |
|
2020 |
Yan J, Hedl M, Abraham C. Myeloid Cell-Intrinsic IRF5 Promotes T Cell Responses through Multiple Distinct Checkpoints In Vivo, and Immune-Mediated Disease Risk Variants Modulate These Myeloid Cell Functions. Journal of Immunology (Baltimore, Md. : 1950). PMID 32690658 DOI: 10.4049/Jimmunol.1900743 |
0.492 |
|
2020 |
Hedl M, Sun R, Abraham C. Disease Risk-Associated Genetic Variants in and Function in a Complementary Manner to Increase Pattern-Recognition Receptor-Induced Outcomes in Human Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 32661180 DOI: 10.4049/Jimmunol.1901112 |
0.512 |
|
2020 |
Yan J, Pandey SP, Barnes BJ, Turner JR, Abraham C. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation. Cell Reports. 31: 107820. PMID 32610123 DOI: 10.1016/J.Celrep.2020.107820 |
0.492 |
|
2020 |
Sun R, Abraham C. IL23 promotes antimicrobial pathways in human macrophages which are reduced with the IBD-protective IL23R R381Q variant. Cellular and Molecular Gastroenterology and Hepatology. PMID 32474165 DOI: 10.1016/J.Jcmgh.2020.05.007 |
0.429 |
|
2019 |
Huang C, Hedl M, Ranjan K, Abraham C. LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes. Cell Reports. 29: 4525-4539.e4. PMID 31875558 DOI: 10.1016/J.Celrep.2019.11.105 |
0.335 |
|
2019 |
Hedl M, Sun R, Huang C, Abraham C. STAT3 and STAT5 Signaling Thresholds Determine Distinct Regulation for Innate Receptor-Induced Inflammatory Cytokines, and / Disease Variants Modulate These Outcomes. Journal of Immunology (Baltimore, Md. : 1950). PMID 31732533 DOI: 10.4049/Jimmunol.1900031 |
0.508 |
|
2019 |
Pandey SP, Yan J, Turner JR, Abraham C. Correction to: Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens. Mucosal Immunology. PMID 31182816 DOI: 10.1038/S41385-019-0179-8 |
0.302 |
|
2019 |
Sun R, Hedl M, Abraham C. IL23 induces IL23R recycling and amplifies innate receptor-induced signalling and cytokines in human macrophages, and the IBD-protective IL23R R381Q variant modulates these outcomes. Gut. PMID 31097538 DOI: 10.1136/Gutjnl-2018-316830 |
0.452 |
|
2019 |
Pandey SP, Yan J, Turner JR, Abraham C. Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens. Mucosal Immunology. PMID 31053739 DOI: 10.1038/S41385-019-0165-1 |
0.444 |
|
2019 |
Sun R, Hedl M, Abraham C. Twist1 and Twist2 Induce Human Macrophage Memory upon Chronic Innate Receptor Treatment by HDAC-Mediated Deacetylation of Cytokine Promoters. Journal of Immunology (Baltimore, Md. : 1950). PMID 31028123 DOI: 10.4049/Jimmunol.1800757 |
0.392 |
|
2019 |
Gettler K, Giri M, Kenigsberg E, Martin J, Chuang LS, Hsu NY, Denson LA, Hyams JS, Griffiths A, Noe JD, Crandall WV, Mack DR, Kellermayer R, Abraham C, Hoffman G, et al. Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets. Genes and Immunity. PMID 30692607 DOI: 10.1038/S41435-019-0059-Y |
0.338 |
|
2018 |
Hedl M, Yan J, Witt H, Abraham C. IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and Immune-Mediated Disease Risk Variants Modulate This Outcome. Journal of Immunology (Baltimore, Md. : 1950). PMID 30593537 DOI: 10.4049/Jimmunol.1800226 |
0.431 |
|
2018 |
Luong PH, Hedl M, Yan J, Zuo T, Fu TM, Jiang X, Thiagarajah JR, Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. Elife. 7. PMID 30355448 DOI: 10.7554/Elife.38539 |
0.442 |
|
2018 |
Luong P, Hedl M, Yan J, Zuo T, Fu T, Jiang X, Thiagarajah JR, Hansen SH, Lesser CF, Wu H, Abraham C, Lencer WI. Author response: INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling Elife. DOI: 10.7554/Elife.38539.018 |
0.316 |
|
2017 |
Bist P, Cheong WS, Ng A, Dikshit N, Kim BH, Pulloor NK, Khameneh HJ, Hedl M, Shenoy AR, Balamuralidhar V, Malik NBA, Hong M, Neutzner A, Chin KC, Kobayashi KS, ... ... Abraham C, et al. E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP. Nature Communications. 8: 15865. PMID 28656966 DOI: 10.1038/Ncomms15865 |
0.406 |
|
2017 |
Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm NW, Yang Y, Yu H, Li HB, Wang G, Lei X, de Zoete MR, Zhao J, Zheng Y, Chen H, ... ... Abraham C, et al. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature. PMID 28636595 DOI: 10.1038/Nature22967 |
0.396 |
|
2017 |
Lahiri A, Hedl M, Yan J, Abraham C. Human LACC1 increases innate receptor-induced responses and a LACC1 disease-risk variant modulates these outcomes. Nature Communications. 8: 15614. PMID 28593945 DOI: 10.1038/Ncomms15614 |
0.452 |
|
2017 |
Yan J, Hedl M, Abraham C. An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes. The Journal of Clinical Investigation. PMID 28436939 DOI: 10.1172/Jci86282 |
0.475 |
|
2017 |
Schumacher MA, Hedl M, Abraham C, Bernard JK, Lozano PR, Hsieh JJ, Almohazey D, Bucar EB, Punit S, Dempsey PJ, Frey MR. ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation. Cell Death & Disease. 8: e2622. PMID 28230865 DOI: 10.1038/Cddis.2017.42 |
0.426 |
|
2016 |
Abraham C, Dulai PS, Vermeire S, Sandborn WJ. Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases. Gastroenterology. PMID 27780712 DOI: 10.1053/J.Gastro.2016.10.018 |
0.467 |
|
2016 |
Hedl M, Proctor DD, Abraham C. JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 27664279 DOI: 10.4049/Jimmunol.1600845 |
0.528 |
|
2016 |
Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV. ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. The Journal of Clinical Investigation. PMID 27617863 DOI: 10.1172/Jci85329 |
0.36 |
|
2016 |
Hedl M, Yan J, Abraham C. IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation. Cell Reports. PMID 27545875 DOI: 10.1016/J.Celrep.2016.07.060 |
0.45 |
|
2016 |
Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, ... ... Abraham C, et al. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nature Communications. 7: 12342. PMID 27503255 DOI: 10.1038/Ncomms12342 |
0.348 |
|
2016 |
Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, ... ... Abraham C, et al. A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF. Gastroenterology. PMID 27377463 DOI: 10.1053/J.Gastro.2016.06.045 |
0.355 |
|
2015 |
Lahiri A, Hedl M, Abraham C. MTMR3 risk allele enhances innate receptor-induced signaling and cytokines by decreasing autophagy and increasing caspase-1 activation. Proceedings of the National Academy of Sciences of the United States of America. 112: 10461-6. PMID 26240347 DOI: 10.1073/Pnas.1501752112 |
0.464 |
|
2015 |
Hedl M, Abraham C. A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion. Gut. PMID 26215868 DOI: 10.1136/Gutjnl-2014-308922 |
0.483 |
|
2015 |
Zheng S, Hedl M, Abraham C. Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators. Journal of Immunology (Baltimore, Md. : 1950). 195: 217-26. PMID 26019273 DOI: 10.4049/Jimmunol.1402808 |
0.419 |
|
2015 |
Wu X, Lahiri A, Sarin R, Abraham C. T cell-extrinsic CD18 attenuates antigen-dependent CD4+ T cell activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 194: 4122-9. PMID 25801431 DOI: 10.4049/Jimmunol.1401328 |
0.362 |
|
2015 |
Zheng S, Hedl M, Abraham C. TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 194: 1928-37. PMID 25567680 DOI: 10.4049/Jimmunol.1401933 |
0.462 |
|
2014 |
Hedl M, Abraham C. A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1. Proceedings of the National Academy of Sciences of the United States of America. 111: 13451-6. PMID 25197060 DOI: 10.1073/Pnas.1404178111 |
0.484 |
|
2014 |
Lahiri A, Abraham C. Activation of pattern recognition receptors up-regulates metallothioneins, thereby increasing intracellular accumulation of zinc, autophagy, and bacterial clearance by macrophages. Gastroenterology. 147: 835-46. PMID 24960189 DOI: 10.1053/J.Gastro.2014.06.024 |
0.419 |
|
2014 |
Hedl M, Zheng S, Abraham C. The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways. Journal of Immunology (Baltimore, Md. : 1950). 192: 5924-32. PMID 24842757 DOI: 10.4049/Jimmunol.1302727 |
0.43 |
|
2014 |
Hedl M, Lahiri A, Ning K, Cho JH, Abraham C. Pattern recognition receptor signaling in human dendritic cells is enhanced by ICOS ligand and modulated by the Crohn's disease ICOSLG risk allele. Immunity. 40: 734-46. PMID 24837102 DOI: 10.1016/J.Immuni.2014.04.011 |
0.452 |
|
2014 |
Wu X, Lahiri A, Haines GK, Flavell RA, Abraham C. NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury. Journal of Immunology (Baltimore, Md. : 1950). 192: 3409-18. PMID 24591373 DOI: 10.4049/Jimmunol.1302436 |
0.463 |
|
2013 |
Zheng S, Abraham C. NF-κB1 inhibits NOD2-induced cytokine secretion through ATF3-dependent mechanisms. Molecular and Cellular Biology. 33: 4857-71. PMID 24100018 DOI: 10.1128/Mcb.00797-13 |
0.42 |
|
2013 |
Zhang CK, Hewett J, Hemming J, Grant T, Zhao H, Abraham C, Oikonomou I, Kanakia M, Cho JH, Proctor DD. The influence of depression on quality of life in patients with inflammatory bowel disease. Inflammatory Bowel Diseases. 19: 1732-9. PMID 23669400 DOI: 10.1097/Mib.0B013E318281F395 |
0.308 |
|
2013 |
Su L, Nalle SC, Shen L, Turner ES, Singh G, Breskin LA, Khramtsova EA, Khramtsova G, Tsai PY, Fu YX, Abraham C, Turner JR. TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 145: 407-15. PMID 23619146 DOI: 10.1053/J.Gastro.2013.04.011 |
0.409 |
|
2013 |
Zhang W, Hui KY, Gusev A, Warner N, Ng SM, Ferguson J, Choi M, Burberry A, Abraham C, Mayer L, Desnick RJ, Cardinale CJ, Hakonarson H, Waterman M, Chowers Y, et al. Extended haplotype association study in Crohn's disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-κB pathway gene, HEATR3. Genes and Immunity. 14: 310-6. PMID 23615072 DOI: 10.1038/Gene.2013.19 |
0.356 |
|
2013 |
Shen H, Zhang W, Abraham C, Cho JH. Age and CD161 expression contribute to inter-individual variation in interleukin-23 response in CD8+ memory human T cells. Plos One. 8: e57746. PMID 23469228 DOI: 10.1371/Journal.Pone.0057746 |
0.406 |
|
2013 |
Hedl M, Abraham C. Negative regulation of human mononuclear phagocyte function Mucosal Immunology. 6: 205-223. PMID 23340822 DOI: 10.1038/Mi.2012.139 |
0.401 |
|
2013 |
Hedl M, Abraham C. NLRP1 and NLRP3 inflammasomes are essential for distinct outcomes of decreased cytokines but enhanced bacterial killing upon chronic Nod2 stimulation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G583-96. PMID 23287275 DOI: 10.1152/Ajpgi.00297.2012 |
0.451 |
|
2012 |
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, ... ... Abraham C, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 491: 119-24. PMID 23128233 DOI: 10.1038/Nature11582 |
0.399 |
|
2012 |
Huber S, Gagliani N, Zenewicz LA, Huber FJ, Bosurgi L, Hu B, Hedl M, Zhang W, O'Connor W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Booth CJ, Cho JH, Ouyang W, ... Abraham C, et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature. 491: 259-63. PMID 23075849 DOI: 10.1038/Nature11535 |
0.396 |
|
2012 |
Hedl M, Abraham C. Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines. Gastroenterology. 143: 1530-43. PMID 22967725 DOI: 10.1053/J.Gastro.2012.08.048 |
0.459 |
|
2012 |
Sarin R, Abraham C. CD18 is required for optimal lymphopenia-induced proliferation of mouse T cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G851-60. PMID 22821945 DOI: 10.1152/Ajpgi.00520.2011 |
0.392 |
|
2012 |
Zhang W, Ferguson J, Ng SM, Hui K, Goh G, Lin A, Esplugues E, Flavell RA, Abraham C, Zhao H, Cho JH. Effector CD4+ T cell expression signatures and immune-mediated disease associated genes. Plos One. 7: e38510. PMID 22715389 DOI: 10.1371/Journal.Pone.0038510 |
0.442 |
|
2012 |
Hedl M, Abraham C. IRF5 risk polymorphisms contribute to interindividual variance in pattern recognition receptor-mediated cytokine secretion in human monocyte-derived cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 5348-56. PMID 22544929 DOI: 10.4049/Jimmunol.1103319 |
0.469 |
|
2012 |
Kenny EE, Pe'er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant SR, Bressman S, Burns ER, et al. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. Plos Genetics. 8: e1002559. PMID 22412388 DOI: 10.1371/Journal.Pgen.1002559 |
0.323 |
|
2011 |
Menard L, Saadoun D, Isnardi I, Ng YS, Meyers G, Massad C, Price C, Abraham C, Motaghedi R, Buckner JH, Gregersen PK, Meffre E. The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. The Journal of Clinical Investigation. 121: 3635-44. PMID 21804190 DOI: 10.1172/Jci45790 |
0.338 |
|
2011 |
Hedl M, Abraham C. Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages. The Journal of Biological Chemistry. 286: 26440-9. PMID 21659536 DOI: 10.1074/Jbc.M111.237495 |
0.405 |
|
2011 |
Sarin R, Wu X, Abraham C. Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses. Proceedings of the National Academy of Sciences of the United States of America. 108: 9560-5. PMID 21606346 DOI: 10.1073/Pnas.1017854108 |
0.469 |
|
2011 |
Abraham C, Medzhitov R. Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology. 140: 1729-37. PMID 21530739 DOI: 10.1053/J.Gastro.2011.02.012 |
0.396 |
|
2011 |
Hedl M, Abraham C. Secretory mediators regulate Nod2-induced tolerance in human macrophages. Gastroenterology. 140: 231-41. PMID 20854823 DOI: 10.1053/J.Gastro.2010.09.009 |
0.499 |
|
2010 |
Capurso NA, Look M, Jeanbart L, Nowyhed H, Abraham C, Craft J, Fahmy TM. Development of a nanoparticulate formulation of retinoic acid that suppresses Th17 cells and upregulates regulatory T cells. Self/Nonself. 1: 335-340. PMID 21487509 DOI: 10.4161/self.1.4.13946 |
0.697 |
|
2010 |
Ballard D, Abraham C, Cho J, Zhao H. Pathway analysis comparison using Crohn's disease genome wide association studies. Bmc Medical Genomics. 3: 25. PMID 20584322 DOI: 10.1186/1755-8794-3-25 |
0.366 |
|
2010 |
Zenewicz LA, Abraham C, Flavell RA, Cho JH. Unraveling the genetics of autoimmunity. Cell. 140: 791-7. PMID 20303870 DOI: 10.1016/J.Cell.2010.03.003 |
0.36 |
|
2010 |
Hedl M, Phatak UP, Abraham C. W1795 An IL-1beta Autocrine Loop is Required for Optimal Acute NOD2 Responses Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63415-4 |
0.302 |
|
2010 |
Hedl M, Abraham C. Chronic Nod2 Stimulation Downregulates Bacteria-induced Inflammatory Cytokines, but Maintains Bacterial Killing Clinical Immunology. 135. DOI: 10.1016/J.Clim.2010.03.328 |
0.384 |
|
2009 |
Molinero LL, Yang J, Gajewski T, Abraham C, Farrar MA, Alegre ML. CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 6736-43. PMID 19454668 DOI: 10.4049/Jimmunol.0900498 |
0.43 |
|
2009 |
Abraham C, Cho J. Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflammatory Bowel Diseases. 15: 1090-100. PMID 19253307 DOI: 10.1002/Ibd.20894 |
0.511 |
|
2009 |
Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C, Turner JR. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology. 136: 551-63. PMID 19027740 DOI: 10.1053/J.Gastro.2008.10.081 |
0.42 |
|
2009 |
Abraham C, Cho JH. IL-23 and autoimmunity: new insights into the pathogenesis of inflammatory bowel disease. Annual Review of Medicine. 60: 97-110. PMID 18976050 DOI: 10.1146/Annurev.Med.60.051407.123757 |
0.517 |
|
2008 |
Molinero LL, Zhou P, Wang Y, Harlin H, Kee B, Abraham C, Alegre ML. Epidermal Langerhans cells promote skin allograft rejection in mice with NF-kappa B-impaired T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8: 21-31. PMID 18021281 DOI: 10.1111/J.1600-6143.2007.02038.X |
0.321 |
|
2008 |
Hedl M, Abraham C. Sa.124. Nod2 Mediates Tolerance in Primary Human Cells Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.345 |
0.324 |
|
2007 |
Hedl M, Li J, Cho JH, Abraham C. Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proceedings of the National Academy of Sciences of the United States of America. 104: 19440-5. PMID 18032608 DOI: 10.1073/Pnas.0706097104 |
0.449 |
|
2007 |
Abraham C, Cho JH. Bugging of the intestinal mucosa. The New England Journal of Medicine. 357: 708-10. PMID 17699823 DOI: 10.1056/Nejmcibr073420 |
0.34 |
|
2007 |
Marski M, Ye AL, Abraham C. CD18 is required for intestinal T cell responses at multiple immune checkpoints. Journal of Immunology (Baltimore, Md. : 1950). 178: 2104-12. PMID 17277114 DOI: 10.4049/Jimmunol.178.4.2104 |
0.398 |
|
2007 |
Cho JH, Abraham C. Inflammatory bowel disease genetics: Nod2. Annual Review of Medicine. 58: 401-16. PMID 16987083 DOI: 10.1146/Annurev.Med.58.061705.145024 |
0.39 |
|
2006 |
Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (New York, N.Y.). 314: 1461-3. PMID 17068223 DOI: 10.1126/Science.1135245 |
0.422 |
|
2006 |
Wang F, Schwarz BT, Graham WV, Wang Y, Su L, Clayburgh DR, Abraham C, Turner JR. IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction. Gastroenterology. 131: 1153-63. PMID 17030185 DOI: 10.1053/J.Gastro.2006.08.022 |
0.419 |
|
2006 |
Abraham C, Cho JH. Functional consequences of NOD2 (CARD15) mutations. Inflammatory Bowel Diseases. 12: 641-50. PMID 16804402 DOI: 10.1097/01.Mib.0000225332.83861.5F |
0.407 |
|
2005 |
Marski M, Kandula S, Turner JR, Abraham C. CD18 is required for optimal development and function of CD4+CD25+ T regulatory cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 7889-97. PMID 16339524 DOI: 10.4049/Jimmunol.175.12.7889 |
0.338 |
|
2005 |
Wang J, Anders RA, Wang Y, Turner JR, Abraham C, Pfeffer K, Fu YX. The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease. Journal of Immunology (Baltimore, Md. : 1950). 174: 8173-82. PMID 15944326 DOI: 10.4049/Jimmunol.174.12.8173 |
0.429 |
|
2004 |
Kandula S, Abraham C. LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 173: 4443-51. PMID 15383575 DOI: 10.4049/Jimmunol.173.7.4443 |
0.371 |
|
2004 |
Li J, Moran T, Swanson E, Julian C, Harris J, Bonen DK, Hedl M, Nicolae DL, Abraham C, Cho JH. Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations. Human Molecular Genetics. 13: 1715-25. PMID 15198989 DOI: 10.1093/Hmg/Ddh182 |
0.413 |
|
2001 |
Abraham C, Miller J. Molecular Mechanisms of IL-2 Gene Regulation Following Costimulation Through LFA-1 Journal of Immunology. 167: 5193-5201. PMID 11673532 DOI: 10.4049/Jimmunol.167.9.5193 |
0.417 |
|
2000 |
Abraham C, Miller J. Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1 Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)83455-1 |
0.344 |
|
1998 |
Abraham C, Scaglione–Sewell B, Skarosi SF, Qin W, Bissonnette M, Brasitus TA. Protein kinase C α modulates growth and differentiation in Caco-2 cells Gastroenterology. 114: 503-509. PMID 9496940 DOI: 10.1016/S0016-5085(98)70533-5 |
0.311 |
|
1998 |
Abraham C, Griffith J, Miller J. The role of LFA-1 in T cell activation cannot be compensated for by enhancing T cell receptor engagement Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)83734-7 |
0.336 |
|
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