Year |
Citation |
Score |
2022 |
Vanover D, Zurla C, Peck HE, Orr-Burks N, Joo JY, Murray J, Holladay N, Hobbs RA, Jung Y, Chaves LCS, Rotolo L, Lifland AW, Olivier AK, Li D, Saunders KO, ... ... Santangelo PJ, et al. Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2202771. PMID 36316224 DOI: 10.1002/advs.202202771 |
0.752 |
|
2021 |
Braun MR, Noton SL, Blanchard EL, Shareef A, Santangelo PJ, Johnson WE, Fearns R. Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts. Plos Pathogens. 17: e1009589. PMID 34003848 DOI: 10.1371/journal.ppat.1009589 |
0.381 |
|
2021 |
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, ... ... Santangelo PJ, et al. The NIH Somatic Cell Genome Editing program. Nature. 592: 195-204. PMID 33828315 DOI: 10.1038/s41586-021-03191-1 |
0.431 |
|
2021 |
Blanchard EL, Vanover D, Bawage SS, Tiwari PM, Rotolo L, Beyersdorf J, Peck HE, Bruno NC, Hincapie R, Michel F, Murray J, Sadhwani H, Vanderheyden B, Finn MG, Brinton MA, ... ... Santangelo PJ, et al. Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents. Nature Biotechnology. PMID 33536629 DOI: 10.1038/s41587-021-00822-w |
0.388 |
|
2020 |
Blanchard EL, Braun MR, Lifland AW, Ludeke B, Noton SL, Vanover D, Zurla C, Fearns R, Santangelo PJ. Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection. Plos Pathogens. 16: e1008987. PMID 33031461 DOI: 10.1371/journal.ppat.1008987 |
0.785 |
|
2020 |
Paunovska K, Da Silva Sanchez A, Foster MT, Loughrey D, Blanchard EL, Islam FZ, Gan Z, Mantalaris A, Santangelo PJ, Dahlman JE. Increased PIP3 activity blocks nanoparticle mRNA delivery. Science Advances. 6: eaba5672. PMID 32743074 DOI: 10.1126/Sciadv.Aba5672 |
0.38 |
|
2020 |
Lindsay KE, Vanover D, Thoresen M, King H, Xiao P, Badial P, Araínga M, Park SB, Tiwari PM, Peck HE, Blanchard EL, Feugang JM, Olivier AK, Zurla C, Villinger F, ... ... Santangelo PJ, et al. Aerosol Delivery of Synthetic mRNA to Vaginal Mucosa Leads to Durable Expression of Broadly Neutralizing Antibodies against HIV. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31995741 DOI: 10.1016/J.Ymthe.2020.01.002 |
0.327 |
|
2019 |
Lokugamage MP, Gan Z, Zurla C, Levin J, Islam FZ, Kalathoor S, Sato M, Sago CD, Santangelo PJ, Dahlman JE. Mild Innate Immune Activation Overrides Efficient Nanoparticle-Mediated RNA Delivery. Advanced Materials (Deerfield Beach, Fla.). e1904905. PMID 31743531 DOI: 10.1002/Adma.201904905 |
0.368 |
|
2019 |
Blanchard EL, Argyropoulou D, Zurla C, Bhosle SM, Vanover D, Santangelo PJ. Quantification and localization of protein-RNA interactions in patient-derived archival tumor tissue. Cancer Research. PMID 31481502 DOI: 10.1158/0008-5472.Can-19-1094 |
0.388 |
|
2019 |
Lindsay KE, Bhosle SM, Zurla C, Beyersdorf J, Rogers KA, Vanover D, Xiao P, Araínga M, Shirreff LM, Pitard B, Baumhof P, Villinger F, Santangelo PJ. Visualization of early events in mRNA vaccine delivery in non-human primates via PET-CT and near-infrared imaging. Nature Biomedical Engineering. PMID 30936432 DOI: 10.1038/S41551-019-0378-3 |
0.324 |
|
2018 |
Blanchard EL, Loomis KH, Bhosle SM, Vanover D, Baumhof P, Pitard B, Zurla C, Santangelo PJ. Proximity Ligation Assays for In Situ Detection of Innate Immune Activation: Focus on In Vitro-Transcribed mRNA. Molecular Therapy. Nucleic Acids. 14: 52-66. PMID 30579042 DOI: 10.1016/J.Omtn.2018.11.002 |
0.339 |
|
2018 |
Xu Y, Huang L, Kirschman JL, Vanover DA, Tiwari PM, Santangelo PJ, Shen X, Russell DG. Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo. Journal of Immunology (Baltimore, Md. : 1950). PMID 30541883 DOI: 10.4049/Jimmunol.1800924 |
0.353 |
|
2018 |
Tiwari PM, Vanover D, Lindsay KE, Bawage SS, Kirschman JL, Bhosle S, Lifland AW, Zurla C, Santangelo PJ. Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection. Nature Communications. 9: 3999. PMID 30275522 DOI: 10.1038/S41467-018-06508-3 |
0.761 |
|
2018 |
Sago CD, Lokugamage MP, Paunovska K, Vanover DA, Monaco CM, Shah NN, Gamboa Castro M, Anderson SE, Rudoltz TG, Lando GN, Mummilal Tiwari P, Kirschman JL, Willett N, Jang YC, Santangelo PJ, et al. High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing. Proceedings of the National Academy of Sciences of the United States of America. PMID 30275336 DOI: 10.1073/Pnas.1811276115 |
0.402 |
|
2018 |
Loomis KH, Lindsay KE, Zurla C, Bhosle SM, Vanover DA, Blanchard EL, Kirschman JL, Bellamkonda RV, Santangelo PJ. In vitro transcribed messenger RNA vaccines with programmable stimulation of innate immunity. Bioconjugate Chemistry. PMID 30067354 DOI: 10.1021/Acs.Bioconjchem.8B00443 |
0.305 |
|
2018 |
Bhosle SM, Loomis KH, Kirschman JL, Blanchard EL, Vanover DA, Zurla C, Habrant D, Edwards D, Baumhof P, Pitard B, Santangelo PJ. Unifying in vitro and in vivo IVT mRNA expression discrepancies in skeletal muscle via mechanotransduction. Biomaterials. 159: 189-203. PMID 29331806 DOI: 10.1016/J.Biomaterials.2018.01.010 |
0.375 |
|
2017 |
Santangelo PJ, Cicala C, Byrareddy SN, Ortiz KT, Little D, Lindsay KE, Gumber S, Hong JJ, Jelicic K, Rogers KA, Zurla C, Villinger F, Ansari AA, Fauci AS, Arthos J. Early treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection. Mucosal Immunology. PMID 29346349 DOI: 10.1038/Mi.2017.112 |
0.31 |
|
2017 |
Vanover D, Smith DV, Blanchard EL, Alonas E, Kirschman JL, Lifland AW, Zurla C, Santangelo PJ. RSV glycoprotein and genomic RNA dynamics reveal filament assembly prior to the plasma membrane. Nature Communications. 8: 667. PMID 28939853 DOI: 10.1038/S41467-017-00732-Z |
0.771 |
|
2017 |
Kirschman JL, Bhosle S, Vanover D, Blanchard EL, Loomis KH, Zurla C, Murray K, Lam BC, Santangelo PJ. Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA-protein correlations at the level of single cells. Nucleic Acids Research. PMID 28449134 DOI: 10.1093/Nar/Gkx290 |
0.45 |
|
2017 |
Udhayakumar VK, De Beuckelaer A, McCaffrey J, McCrudden CM, Kirschman JL, Vanover D, Van Hoecke L, Roose K, Deswarte K, De Geest BG, Lienenklaus S, Santangelo PJ, Grooten J, McCarthy HO, De Koker S. Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide. Advanced Healthcare Materials. PMID 28436620 DOI: 10.1002/Adhm.201601412 |
0.37 |
|
2017 |
Hampton CM, Strauss JD, Ke Z, Dillard RS, Hammonds JE, Alonas E, Desai TM, Marin M, Storms RE, Leon F, Melikyan GB, Santangelo PJ, Spearman PW, Wright ER. Correlated fluorescence microscopy and cryo-electron tomography of virus-infected or transfected mammalian cells. Nature Protocols. 12: 150-167. PMID 27977021 DOI: 10.1038/Nprot.2016.168 |
0.327 |
|
2017 |
Zurla C, Jung J, Blanchard EL, Santangelo PJ. A Novel Method to Quantify RNA-Protein Interactions In Situ Using FMTRIP and Proximity Ligation. Methods in Molecular Biology (Clifton, N.J.). 1468: 155-70. PMID 27662876 DOI: 10.1007/978-1-4939-4035-6_12 |
0.475 |
|
2016 |
Loomis KH, Kirschman JL, Bhosle S, Bellamkonda RV, Santangelo PJ. Strategies for modulating innate immune activation and protein production of in vitro transcribed mRNAs. Journal of Materials Chemistry. B. 4: 1619-1632. PMID 32263015 DOI: 10.1039/C5Tb01753J |
0.355 |
|
2016 |
Byrareddy SN, Arthos J, Cicala C, Villinger F, Ortiz KT, Little D, Sidell N, Kane MA, Yu J, Jones JW, Santangelo PJ, Zurla C, McKinnon LR, Arnold KB, Woody CE, et al. Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy. Science (New York, N.Y.). 354: 197-202. PMID 27738167 DOI: 10.1126/Science.Aag1276 |
0.306 |
|
2016 |
Alonas E, Vanover D, Blanchard E, Zurla C, Santangelo PJ. Imaging viral RNA using multiply labeled tetravalent RNA imaging probes in live cells. Methods (San Diego, Calif.). 98: 91-8. PMID 26875782 DOI: 10.1016/J.Ymeth.2016.02.006 |
0.495 |
|
2015 |
Groves B, Chen YJ, Zurla C, Pochekailov S, Kirschman JL, Santangelo PJ, Seelig G. Computing in mammalian cells with nucleic acid strand exchange. Nature Nanotechnology. PMID 26689378 DOI: 10.1038/Nnano.2015.278 |
0.328 |
|
2015 |
Zurla C, Jung J, Santangelo PJ. Can we observe changes in mRNA "state"? Overview of methods to study mRNA interactions with regulatory proteins relevant in cancer related processes. The Analyst. PMID 26605378 DOI: 10.1039/C5An01959A |
0.478 |
|
2015 |
Yi H, Strauss JD, Ke Z, Alonas E, Dillard RS, Hampton CM, Lamb KM, Hammonds JE, Santangelo PJ, Spearman PW, Wright ER. Native Immunogold Labeling of Cell Surface Proteins and Viral Glycoproteins for Cryo-Electron Microscopy and Cryo-Electron Tomography Applications. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. PMID 26069287 DOI: 10.1369/0022155415593323 |
0.357 |
|
2015 |
Santangelo PJ, Rogers KA, Zurla C, Blanchard EL, Gumber S, Strait K, Connor-Stroud F, Schuster DM, Amancha PK, Hong JJ, Byrareddy SN, Hoxie JA, Vidakovic B, Ansari AA, Hunter E, et al. Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy-treated macaques. Nature Methods. 12: 427-32. PMID 25751144 DOI: 10.1038/Nmeth.3320 |
0.398 |
|
2014 |
Byrareddy SN, Kallam B, Arthos J, Cicala C, Nawaz F, Hiatt J, Kersh EN, McNicholl JM, Hanson D, Reimann KA, Brameier M, Walter L, Rogers K, Mayne AE, Dunbar P, ... ... Santangelo PJ, et al. Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection. Nature Medicine. 20: 1397-400. PMID 25419708 DOI: 10.1038/Nm.3715 |
0.328 |
|
2014 |
Kiss G, Holl JM, Williams GM, Alonas E, Vanover D, Lifland AW, Gudheti M, Guerrero-Ferreira RC, Nair V, Yi H, Graham BS, Santangelo PJ, Wright ER. Structural analysis of respiratory syncytial virus reveals the position of M2-1 between the matrix protein and the ribonucleoprotein complex. Journal of Virology. 88: 7602-17. PMID 24760890 DOI: 10.1128/Jvi.00256-14 |
0.757 |
|
2014 |
Alonas E, Lifland AW, Gudheti M, Vanover D, Jung J, Zurla C, Kirschman J, Fiore VF, Douglas A, Barker TH, Yi H, Wright ER, Crowe JE, Santangelo PJ. Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells. Acs Nano. 8: 302-15. PMID 24351207 DOI: 10.1021/Nn405998V |
0.813 |
|
2013 |
Jung J, Lifland AW, Alonas EJ, Zurla C, Santangelo PJ. Characterization of mRNA-cytoskeleton interactions in situ using FMTRIP and proximity ligation. Plos One. 8: e74598. PMID 24040294 DOI: 10.1371/Journal.Pone.0074598 |
0.773 |
|
2013 |
Jung J, Lifland AW, Zurla C, Alonas EJ, Santangelo PJ. Quantifying RNA-protein interactions in situ using modified-MTRIPs and proximity ligation. Nucleic Acids Research. 41: e12. PMID 22952158 DOI: 10.1093/Nar/Gks837 |
0.799 |
|
2013 |
Chen X, Liu Y, Yang X, Wang T, Alonas E, Santangelo PJ, Ren Q, Xi P. Two-color CW STED nanoscopy Proceedings of Spie. 8590: 859017. DOI: 10.1117/12.2001178 |
0.309 |
|
2012 |
Liu Y, Ding Y, Alonas E, Zhao W, Santangelo PJ, Jin D, Piper JA, Teng J, Ren Q, Xi P. Achieving λ/10 resolution CW STED nanoscopy with a Ti:Sapphire oscillator. Plos One. 7: e40003. PMID 22761944 DOI: 10.1371/Journal.Pone.0040003 |
0.33 |
|
2012 |
Lifland AW, Jung J, Alonas E, Zurla C, Crowe JE, Santangelo PJ. Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS. Journal of Virology. 86: 8245-58. PMID 22623778 DOI: 10.1128/Jvi.00215-12 |
0.785 |
|
2012 |
Shaikh FY, Cox RG, Lifland AW, Hotard AL, Williams JV, Moore ML, Santangelo PJ, Crowe JE. A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles. Mbio. 3. PMID 22318318 DOI: 10.1128/Mbio.00270-11 |
0.766 |
|
2012 |
Santangelo PJ, Alonas E, Jung J, Lifland AW, Zurla C. Probes for intracellular RNA imaging in live cells. Methods in Enzymology. 505: 383-99. PMID 22289464 DOI: 10.1016/B978-0-12-388448-0.00028-0 |
0.789 |
|
2011 |
Zurla C, Lifland AW, Santangelo PJ. Characterizing mRNA interactions with RNA granules during translation initiation inhibition. Plos One. 6: e19727. PMID 21573130 DOI: 10.1371/Journal.Pone.0019727 |
0.795 |
|
2011 |
Lifland AW, Zurla C, Yu J, Santangelo PJ. Dynamics of native β-actin mRNA transport in the cytoplasm. Traffic (Copenhagen, Denmark). 12: 1000-11. PMID 21518164 DOI: 10.1111/J.1600-0854.2011.01209.X |
0.763 |
|
2010 |
Lindquist ME, Lifland AW, Utley TJ, Santangelo PJ, Crowe JE. Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication. Journal of Virology. 84: 12274-84. PMID 20844027 DOI: 10.1128/Jvi.00260-10 |
0.785 |
|
2010 |
Lifland AW, Zurla C, Santangelo PJ. Single molecule sensitive multivalent polyethylene glycol probes for RNA imaging. Bioconjugate Chemistry. 21: 483-8. PMID 20141184 DOI: 10.1021/Bc9003876 |
0.798 |
|
2010 |
Santangelo PJ. Molecular beacons and related probes for intracellular RNA imaging. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 2: 11-9. PMID 20049827 DOI: 10.1002/Wnan.52 |
0.451 |
|
2009 |
Santangelo PJ, Lifland AW, Curt P, Sasaki Y, Bassell GJ, Lindquist ME, Crowe JE. Single molecule-sensitive probes for imaging RNA in live cells. Nature Methods. 6: 347-9. PMID 19349979 DOI: 10.1038/Nmeth.1316 |
0.795 |
|
2008 |
Utley TJ, Ducharme NA, Varthakavi V, Shepherd BE, Santangelo PJ, Lindquist ME, Goldenring JR, Crowe JE. Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2. Proceedings of the National Academy of Sciences of the United States of America. 105: 10209-14. PMID 18621683 DOI: 10.1073/Pnas.0712144105 |
0.404 |
|
2008 |
Rhee WJ, Santangelo PJ, Jo H, Bao G. Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons. Nucleic Acids Research. 36: e30. PMID 18276638 DOI: 10.1093/Nar/Gkn039 |
0.577 |
|
2007 |
Santangelo PJ, Bao G. Dynamics of filamentous viral RNPs prior to egress Nucleic Acids Research. 35: 3602-3611. PMID 17485480 DOI: 10.1093/Nar/Gkm246 |
0.599 |
|
2006 |
Santangelo P, Nitin N, Bao G. Nanostructured probes for RNA detection in living cells. Annals of Biomedical Engineering. 34: 39-50. PMID 16463087 DOI: 10.1007/S10439-005-9003-6 |
0.63 |
|
2006 |
Santangelo P, Nitin N, LaConte L, Woolums A, Bao G. Live-cell characterization and analysis of a clinical isolate of bovine respiratory syncytial virus, using molecular beacons. Journal of Virology. 80: 682-8. PMID 16378971 DOI: 10.1128/Jvi.80.2.682-688.2006 |
0.622 |
|
2005 |
Santangelo PJ, Nitin N, Bao G. Direct visualization of mRNA colocalization with mitochondria in living cells using molecular beacons. Journal of Biomedical Optics. 10: 44025. PMID 16178658 DOI: 10.1117/1.2011402 |
0.592 |
|
2004 |
Bao G, Tsourkas A, Santangelo PJ. Engineering nanostructured probes for sensitive intracellular gene detection. Mechanics & Chemistry of Biosystems : McB. 1: 23-36. PMID 16783944 |
0.637 |
|
2004 |
Nitin N, Santangelo PJ, Kim G, Nie S, Bao G. Peptide-linked molecular beacons for efficient delivery and rapid mRNA detection in living cells. Nucleic Acids Research. 32: e58. PMID 15084673 DOI: 10.1093/Nar/Gnh063 |
0.564 |
|
2004 |
Santangelo PJ, Nix B, Tsourkas A, Bao G. Dual FRET molecular beacons for mRNA detection in living cells. Nucleic Acids Research. 32: e57. PMID 15084672 DOI: 10.1093/Nar/Gnh062 |
0.71 |
|
1999 |
Santangelo PJ, Kennedy IM. Droplet lasing spectroscopy applied to droplet stream flames Combustion and Flame. 117: 413-421. DOI: 10.1016/S0010-2180(98)00099-6 |
0.476 |
|
1998 |
Santangelo PJ, Flowers D, Kennedy IM. Demonstration of droplet size and vaporization rate measurements in the near field of a two-phase jet with droplet lasing spectroscopy. Applied Optics. 37: 5573-8. PMID 18286041 DOI: 10.1364/Ao.37.005573 |
0.712 |
|
1998 |
Santangelo PJ, Kennedy IM. Demonstration of Droplet size and vaporization rate measurements in the near field of a two phase jet using droplet lasing spectroscopy Journal of Aerosol Science. 29. DOI: 10.1016/S0021-8502(98)00557-6 |
0.473 |
|
1998 |
Santangelo PJ, Flowers D, Kennedy IM. Demonstration of droplet size and vaporization rate measurements in the near field of a two-phase jet with droplet lasing spectroscopy Applied Optics. 37: 5573-5578. |
0.428 |
|
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