David M. Lynn - Publications

Affiliations: 
Chemical and Biological Engineering University of Wisconsin, Madison, Madison, WI 
Area:
(i) the design and synthesis of functional organic materials and (ii) the fabrication and physical characterization of macromolecular assemblies, nanoscale materials, and interfaces
Website:
http://www.chem.wisc.edu/users/dlynn

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Rodríguez López AL, Lee MR, Wang NB, Dunn KK, Sanchez H, Raman N, Andes DR, Lynn DM, Palecek SP. Small-molecule morphogenesis modulators enhance the ability of 14-helical β-peptides to prevent biofilm formation. Antimicrobial Agents and Chemotherapy. PMID 31209011 DOI: 10.1128/AAC.02653-18  0.36
2019 de L Rodríguez López A, Lee MR, Ortiz BJ, Gastfriend BD, Whitehead R, Lynn DM, Palecek SP. Preventing S. aureus biofilm formation on titanium surfaces by the release of antimicrobial β-peptides from polyelectrolyte multilayers. Acta Biomaterialia. PMID 30831325 DOI: 10.1016/j.actbio.2019.02.047  0.48
2018 Lee MR, Raman N, Ortiz-Bermúdez P, Lynn DM, Palecek SP. 14-Helical β-Peptides Elicit Toxicity against C. albicans by Forming Pores in the Cell Membrane and Subsequently Disrupting Intracellular Organelles. Cell Chemical Biology. PMID 30581136 DOI: 10.1016/j.chembiol.2018.11.002  0.36
2017 Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. Incorporation of β-peptides enhances the antifungal activity and selectivity of the helical antimicrobial peptide aurein 1.2. Acs Chemical Biology. PMID 29091404 DOI: 10.1021/acschembio.7b00843  0.36
2017 Zayas-Gonzalez YM, Ortiz BJ, Lynn DM. Layer-by-Layer Assembly of Amine-Reactive Multilayers Using an Azlactone-Functionalized Polymer and Small-Molecule Diamine Linkers. Biomacromolecules. PMID 28332831 DOI: 10.1021/acs.biomac.7b00043  0.64
2017 Kratochvil MJ, Carter MC, Lynn DM. Amine-Reactive Azlactone-Containing Nanofibers For the Immobilization and Patterning of New Functionality on Nanofiber-Based Scaffolds. Acs Applied Materials & Interfaces. PMID 28234454 DOI: 10.1021/acsami.7b00219  0.84
2017 Kratochvil MJ, Yang T, Blackwell HE, Lynn DM. Non-Woven Polymer Nanofiber Coatings that Inhibit Quorum Sensing in Staphylococcus aureus: Toward New Non-Bactericidal Approaches to Infection Control. Acs Infectious Diseases. PMID 28118541 DOI: 10.1021/acsinfecdis.6b00173  0.84
2016 Manna U, Raman N, Welsh MA, Zayas-Gonzalez YM, Blackwell HE, Palecek SP, Lynn DM. Slippery Liquid-Infused Porous Surfaces that Prevent Microbial Surface Fouling and Kill Non-Adherent Pathogens in Surrounding Media: A Controlled Release Approach. Advanced Functional Materials. 26: 3599-3611. PMID 28713229 DOI: 10.1002/adfm.201505522  0.84
2016 Appadoo V, Carter MC, Lynn DM. Controlling the surface-mediated release of DNA using 'mixed multilayers'. Bioengineering & Translational Medicine. 1: 181-192. PMID 27981243 DOI: 10.1002/btm2.10023  0.32
2016 Kratochvil MJ, Welsh MA, Manna U, Ortiz BJ, Blackwell HE, Lynn DM. Slippery Liquid-Infused Porous Surfaces that Prevent Bacterial Surface Fouling and Inhibit Virulence Phenotypes in Surrounding Planktonic Cells. Acs Infectious Diseases. 2: 509-517. PMID 27626103 DOI: 10.1021/acsinfecdis.6b00065  0.84
2016 Zayas-Gonzalez YM, Lynn DM. Degradable Amine-Reactive Coatings Fabricated by the Covalent Layer-by-Layer Assembly of Poly(2-Vinyl-4,4-Dimethylazlactone) with Degradable Polyamine Building Blocks. Biomacromolecules. PMID 27525718 DOI: 10.1021/acs.biomac.6b00975  0.64
2016 Raman N, Lee MR, Rodríguez López AL, Palecek SP, Lynn DM. Antifungal Activity of a β-Peptide in Synthetic Urine Media: Toward Materials-Based Approaches to Reducing Catheter-Associated Urinary Tract Fungal Infections. Acta Biomaterialia. PMID 27422198 DOI: 10.1016/j.actbio.2016.07.016  0.36
2016 Raman N, Marchillo K, Lee MR, Rodríguez López AL, Andes DR, Palecek SP, Lynn DM. Intraluminal Release of an Antifungal β-Peptide Enhances the Antifungal and Anti-Biofilm Activities of Multilayer-Coated Catheters in a Rat Model of Venous Catheter Infection. Acs Biomaterials Science & Engineering. 2: 112-121. PMID 26807439 DOI: 10.1021/acsbiomaterials.5b00427  0.84
2015 Guo X, Manna U, Abbott NL, Lynn DM. Covalent Immobilization of 'Caged' Liquid Crystal Microdroplets on Surfaces. Acs Applied Materials & Interfaces. PMID 26562466 DOI: 10.1021/acsami.5b09595  0.84
2015 Carter MC, Miller DS, Jennings J, Wang X, Mahanthappa MK, Abbott NL, Lynn DM. Synthetic Mimics of Bacterial Lipid A Trigger Optical Transitions in Liquid Crystal Microdroplets at Ultralow Picogram-per-Milliliter Concentrations. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 26562069 DOI: 10.1021/acs.langmuir.5b03557  0.84
2015 Kratochvil MJ, Tal-Gan Y, Yang T, Blackwell HE, Lynn DM. Nanoporous Superhydrophobic Coatings that Promote the Extended Release of Water-Labile Quorum Sensing Inhibitors and Enable Long-Term Modulation of Quorum Sensing in Staphylococcus aureus. Acs Biomaterials Science & Engineering. 1: 1039-1049. PMID 26501126 DOI: 10.1021/acsbiomaterials.5b00313  0.84
2015 Holden MT, Carter MC, Wu CH, Wolfer J, Codner E, Sussman MR, Lynn DM, Smith LM. Photolithographic Synthesis of High-Density DNA and RNA Arrays on Flexible, Transparent, and Easily Sub-Divided Plastic Substrates. Analytical Chemistry. PMID 26494264 DOI: 10.1021/acs.analchem.5b02893  0.84
2015 Raman N, Lee MR, Lynn DM, Palecek SP. Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species. Pharmaceuticals (Basel, Switzerland). 8: 483-503. PMID 26287212 DOI: 10.3390/ph8030483  0.84
2015 Yu Y, Si Y, Bechler SL, Liu B, Lynn DM. Polymer Multilayers that Promote the Rapid Release and Contact Transfer of DNA. Biomacromolecules. PMID 26285737 DOI: 10.1021/acs.biomac.5b00905  0.84
2015 Manna U, Lynn DM. Fabrication of liquid-infused surfaces using reactive polymer multilayers: principles for manipulating the behaviors and mobilities of aqueous fluids on slippery liquid interfaces. Advanced Materials (Deerfield Beach, Fla.). 27: 3007-12. PMID 25854608 DOI: 10.1002/adma.201500893  0.84
2015 Manna U, Lynn DM. Synthetic Surfaces with Robust and Tunable Underwater Superoleophobicity Advanced Functional Materials. 25: 1672-1681. DOI: 10.1002/adfm.201403735  0.84
2014 Carlton RJ, Zayas-Gonzalez YM, Manna U, Lynn DM, Abbott NL. Surfactant-induced ordering and wetting transitions of droplets of thermotropic liquid crystals "caged" inside partially filled polymeric capsules. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 14944-53. PMID 24911044 DOI: 10.1021/la501596b  0.84
2014 Muller JP, Aytar BS, Kondo Y, Lynn DM, Abbott NL. Influence of the Phase State of Self-Assembling Redox Mediators on their Electrochemical Activity. Aiche Journal. American Institute of Chemical Engineers. 60: 1381-1392. PMID 24882870 DOI: 10.1002/aic.14402  0.84
2014 Raman N, Lee MR, Palecek SP, Lynn DM. Polymer multilayers loaded with antifungal β-peptides kill planktonic Candida albicans and reduce formation of fungal biofilms on the surfaces of flexible catheter tubes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 191: 54-62. PMID 24862322 DOI: 10.1016/j.jconrel.2014.05.026  0.84
2014 Lee MR, Raman N, Gellman SH, Lynn DM, Palecek SP. Hydrophobicity and helicity regulate the antifungal activity of 14-helical β-peptides. Acs Chemical Biology. 9: 1613-21. PMID 24837702 DOI: 10.1021/cb500203e  0.84
2014 Broderick AH, Stacy DM, Tal-Gan Y, Kratochvil MJ, Blackwell HE, Lynn DM. Surface coatings that promote rapid release of peptide-based AgrC inhibitors for attenuation of quorum sensing in Staphylococcus aureus. Advanced Healthcare Materials. 3: 97-105. PMID 23813683 DOI: 10.1002/adhm.201300119  0.84
2014 Speetjens FW, Carter MCD, Kim M, Gopalan P, Mahanthappa MK, Lynn DM. Post-fabrication placement of arbitrary chemical functionality on microphase-separated thin films of amine-reactive block copolymers Acs Macro Letters. 3: 1178-1182. DOI: 10.1021/mz500654a  0.84
2013 Manna U, Zayas-Gonzalez YM, Carlton RJ, Caruso F, Abbott NL, Lynn DM. Liquid crystal chemical sensors that cells can wear. Angewandte Chemie (International Ed. in English). 52: 14011-5. PMID 24288229 DOI: 10.1002/anie.201306630  0.84
2013 Manna U, Kratochvil MJ, Lynn DM. Superhydrophobic polymer multilayers that promote the extended, long-term release of embedded water-soluble agents. Advanced Materials (Deerfield Beach, Fla.). 25: 6405-9. PMID 23983053 DOI: 10.1002/adma.201302561  0.84
2013 Aytar BS, Muller JP, Kondo Y, Abbott NL, Lynn DM. Spatial control of cell transfection using soluble or solid-phase redox agents and a redox-active ferrocenyl lipid. Acs Applied Materials & Interfaces. 5: 8283-8. PMID 23965341 DOI: 10.1021/am402594z  0.84
2013 Manna U, Lynn DM. Restoration of superhydrophobicity in crushed polymer films by treatment with water: self-healing and recovery of damaged topographic features aided by an unlikely source. Advanced Materials (Deerfield Beach, Fla.). 25: 5104-8. PMID 23943399 DOI: 10.1002/adma.201302217  0.84
2013 Manna U, Lynn DM. Patterning and impregnation of superhydrophobic surfaces using aqueous solutions. Acs Applied Materials & Interfaces. 5: 7731-6. PMID 23931600 DOI: 10.1021/am4026467  0.84
2013 Aytar BS, Muller JP, Kondo Y, Talmon Y, Abbott NL, Lynn DM. Redox-based control of the transformation and activation of siRNA complexes in extracellular environments using ferrocenyl lipids. Journal of the American Chemical Society. 135: 9111-20. PMID 23701636 DOI: 10.1021/ja403546b  0.84
2013 Manna U, Carter MC, Lynn DM. "Shrink-to-fit" superhydrophobicity: thermally-induced microscale wrinkling of thin hydrophobic multilayers fabricated on flexible shrink-wrap substrates. Advanced Materials (Deerfield Beach, Fla.). 25: 3085-9. PMID 23649745 DOI: 10.1002/adma.201300341  0.84
2013 Melamed Yerushalmi S, Buck ME, Lynn DM, Lemcoff NG, Meijler MM. Multivalent alteration of quorum sensing in Staphylococcus aureus. Chemical Communications (Cambridge, England). 49: 5177-9. PMID 23628938 DOI: 10.1039/c3cc41645c  0.84
2013 Saurer EM, Jewell CM, Roenneburg DA, Bechler SL, Torrealba JR, Hacker TA, Lynn DM. Polyelectrolyte multilayers promote stent-mediated delivery of DNA to vascular tissue. Biomacromolecules. 14: 1696-704. PMID 23597075 DOI: 10.1021/bm4005222  0.84
2013 Broderick AH, Breitbach AS, Frei R, Blackwell HE, Lynn DM. Surface-mediated release of a small-molecule modulator of bacterial biofilm formation: a non-bactericidal approach to inhibiting biofilm formation in Pseudomonas aeruginosa. Advanced Healthcare Materials. 2: 993-1000. PMID 23335593 DOI: 10.1002/adhm.201200334  0.84
2013 Broderick AH, Carter MC, Lockett MR, Smith LM, Lynn DM. Fabrication of oligonucleotide and protein arrays on rigid and flexible substrates coated with reactive polymer multilayers. Acs Applied Materials & Interfaces. 5: 351-9. PMID 23237360 DOI: 10.1021/am302285n  0.84
2013 Bechler SL, Si Y, Yu Y, Ren J, Liu B, Lynn DM. Reduction of intimal hyperplasia in injured rat arteries promoted by catheter balloons coated with polyelectrolyte multilayers that contain plasmid DNA encoding PKCδ. Biomaterials. 34: 226-36. PMID 23069712 DOI: 10.1016/j.biomaterials.2012.09.010  0.84
2013 Tocce EJ, Liliensiek SJ, Broderick AH, Jiang Y, Murphy KC, Murphy CJ, Lynn DM, Nealey PF. The influence of biomimetic topographical features and the extracellular matrix peptide RGD on human corneal epithelial contact guidance. Acta Biomaterialia. 9: 5040-51. PMID 23069317 DOI: 10.1016/j.actbio.2012.10.007  0.84
2013 Broderick AH, Lynn DM. Covalent Layer-by-Layer Assembly Using Reactive Polymers Functional Polymers by Post-Polymerization Modification: Concepts, Guidelines, and Applications. 371-406. DOI: 10.1002/9783527655427.ch15  0.84
2013 Zayas-Gonzalez YM, Manna U, Carlton RJ, Abbott NL, Lynn DM. Encapsulation of thermotropic liquid crystals in hollow polymer microcapsules: Design of colloidal liquid crystal-based chemical sensors that function in cellular environments Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 709.  0.84
2013 Yu Y, Si Y, Bechler SL, Liu B, Lynn DM. Polymer-based multilayer coatings for the rapid release of DNA from surfaces: A weak polyelectrolyte approach Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area At the 2013 Aiche Annual Meeting: Global Challenges For Engineering a Sustainable Future. 405-406.  0.84
2012 Buck ME, Lynn DM. Azlactone-Functionalized Polymers as Reactive Platforms for the Design of Advanced Materials: Progress in the Last Ten Years. Polymer Chemistry. 3: 66-80. PMID 29492112 DOI: 10.1039/C1PY00314C  1
2012 Aytar BS, Muller JP, Golan S, Kondo Y, Talmon Y, Abbott NL, Lynn DM. Chemical oxidation of a redox-active, ferrocene-containing cationic lipid: influence on interactions with DNA and characterization in the context of cell transfection. Journal of Colloid and Interface Science. 387: 56-64. PMID 22980739 DOI: 10.1016/j.jcis.2012.07.083  0.84
2012 Manna U, Broderick AH, Lynn DM. Chemical patterning and physical refinement of reactive superhydrophobic surfaces. Advanced Materials (Deerfield Beach, Fla.). 24: 4291-5. PMID 22740370 DOI: 10.1002/adma.201200903  0.84
2012 Muller JP, Aytar BS, Kondo Y, Lynn DM, Abbott NL. Incorporation of DOPE into Lipoplexes formed from a Ferrocenyl Lipid leads to Inverse Hexagonal Nanostructures that allow Redox-Based Control of Transfection in High Serum. Soft Matter. 8: 2608-2619. PMID 22707977 DOI: 10.1039/C2SM00047D  0.84
2012 Broderick AH, Lockett MR, Buck ME, Yuan Y, Smith LM, Lynn DM. In situ Synthesis of Oligonucleotide Arrays on Surfaces Coated with Crosslinked Polymer Multilayers. Chemistry of Materials : a Publication of the American Chemical Society. 24: 939-945. PMID 22611305 DOI: 10.1021/cm202720q  0.84
2012 Aytar BS, Prausnitz MR, Lynn DM. Rapid release of plasmid DNA from surfaces coated with polyelectrolyte multilayers promoted by the application of electrochemical potentials. Acs Applied Materials & Interfaces. 4: 2726-34. PMID 22551230 DOI: 10.1021/am3003632  0.84
2012 Bechler SL, Lynn DM. Reactive polymer multilayers fabricated by covalent layer-by-layer assembly: 1,4-conjugate addition-based approaches to the design of functional biointerfaces. Biomacromolecules. 13: 1523-32. PMID 22468967 DOI: 10.1021/bm300234q  0.84
2012 Bechler SL, Lynn DM. Characterization of degradable polyelectrolyte multilayers fabricated using DNA and a fluorescently-labeled poly(β-amino ester): shedding light on the role of the cationic polymer in promoting surface-mediated gene delivery. Biomacromolecules. 13: 542-52. PMID 22224541 DOI: 10.1021/bm2016338  0.84
2012 Tocce EJ, Broderick AH, Murphy KC, Liliensiek SJ, Murphy CJ, Lynn DM, Nealey PF. Functionalization of reactive polymer multilayers with RGD and an antifouling motif: RGD density provides control over human corneal epithelial cell-substrate interactions. Journal of Biomedical Materials Research. Part A. 100: 84-93. PMID 21972074 DOI: 10.1002/jbm.a.33233  0.84
2012 Aytar BS, Muller JP, Golan S, Hata S, Takahashi H, Kondo Y, Talmon Y, Abbott NL, Lynn DM. Addition of ascorbic acid to the extracellular environment activates lipoplexes of a ferrocenyl lipid and promotes cell transfection. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 249-59. PMID 21963768 DOI: 10.1016/j.jconrel.2011.09.074  0.84
2012 Buck ME, Lynn DM. Azlactone-functionalized polymers as reactive platforms for the design of advanced materials: Progress in the last ten years Polymer Chemistry. 3: 66-80. DOI: 10.1039/c1py00314c  0.84
2012 Broderick AH, Manna U, Lynn DM. Covalent layer-by-layer assembly of water-permeable and water-impermeable polymer multilayers on highly water-soluble and water-sensitive substrates Chemistry of Materials. 24: 1786-1795. DOI: 10.1021/cm300307g  0.84
2012 Lynn DM. A "Multilayered" Approach to the Delivery of DNA: Exploiting the Structure of Polyelectrolyte Multilayers to Promote Surface-Mediated Cell Transfection and Multi-Agent Delivery Multilayer Thin Films: Sequential Assembly of Nanocomposite Materials: Second Edition. 2: 731-748. DOI: 10.1002/9783527646746.ch30  0.84
2011 Buck ME, Lynn DM. Layer-by-Layer Fabrication of Covalently Crosslinked and Reactive Polymer Multilayers Using Azlactone-Functionalized Copolymers: A Platform for the Design of Functional Biointerfaces. Advanced Engineering Materials. 13: B343-B352. PMID 30034272 DOI: 10.1002/adem.201080085  1
2011 Bechler SL, Lynn DM. Design and Synthesis of a Fluorescently End-Labeled Poly(β-amino ester): Application to the Characterization of Degradable Polyelectrolyte Multilayers. Journal of Polymer Science. Part a, Polymer Chemistry. 49: 1572-1581. PMID 21666772 DOI: 10.1002/pola.24578  0.84
2011 Flessner RM, Jewell CM, Anderson DG, Lynn DM. Degradable polyelectrolyte multilayers that promote the release of siRNA. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 7868-76. PMID 21574582 DOI: 10.1021/la200815t  0.84
2011 Golan S, Aytar BS, Muller JP, Kondo Y, Lynn DM, Abbott NL, Talmon Y. Influence of biological media on the structure and behavior of ferrocene-containing cationic lipid/DNA complexes used for DNA delivery. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 6615-21. PMID 21528933 DOI: 10.1021/la200450x  0.84
2011 Broderick AH, Azarin SM, Buck ME, Palecek SP, Lynn DM. Fabrication and selective functionalization of amine-reactive polymer multilayers on topographically patterned microwell cell culture arrays. Biomacromolecules. 12: 1998-2007. PMID 21504222 DOI: 10.1021/bm200296a  0.84
2011 Saurer EM, Flessner RM, Buck ME, Lynn DM. Fabrication of Covalently Crosslinked and Amine-Reactive Microcapsules by Reactive Layer-by-Layer Assembly of Azlactone-Containing Polymer Multilayers on Sacrificial Microparticle Templates. Journal of Materials Chemistry. 21: 1736-1745. PMID 21383867 DOI: 10.1039/C0JM02633F  0.84
2011 Sun B, Flessner RM, Saurer EM, Jewell CM, Fredin NJ, Lynn DM. Characterization of pH-induced changes in the morphology of polyelectrolyte multilayers assembled from poly(allylamine) and low molecular weight poly(acrylic acid). Journal of Colloid and Interface Science. 355: 431-41. PMID 21237465 DOI: 10.1016/j.jcis.2010.12.019  0.84
2011 Flessner RM, Yu Y, Lynn DM. Rapid release of plasmid DNA from polyelectrolyte multilayers: a weak poly(acid) approach. Chemical Communications (Cambridge, England). 47: 550-2. PMID 21103586 DOI: 10.1039/c0cc02926b  0.84
2011 Saurer EM, Yamanouchi D, Liu B, Lynn DM. Delivery of plasmid DNA to vascular tissue in vivo using catheter balloons coated with polyelectrolyte multilayers. Biomaterials. 32: 610-8. PMID 20933275 DOI: 10.1016/j.biomaterials.2010.09.009  0.84
2011 Breitbach AS, Broderick AH, Jewell CM, Gunasekaran S, Lin Q, Lynn DM, Blackwell HE. Surface-mediated release of a synthetic small-molecule modulator of bacterial quorum sensing: gradual release enhances activity. Chemical Communications (Cambridge, England). 47: 370-2. PMID 20830354 DOI: 10.1039/c0cc02316g  0.84
2011 Buck ME, Lynn DM. Layer-by-layer fabrication of covalently crosslinked and reactive polymer multilayers using azlactone-functionalized copolymers: A platform for the design of functional biointerfaces Advanced Engineering Materials. 13: B343-B352. DOI: 10.1002/adem.201080085  0.84
2010 Buck ME, Schwartz SC, Lynn DM. Superhydrophobic Thin Films Fabricated by Reactive Layer-by-Layer Assembly of Azlactone-Functionalized Polymers. Chemistry of Materials : a Publication of the American Chemical Society. 22: 6319-6327. PMID 21151704 DOI: 10.1021/cm102115e  0.84
2010 Saurer EM, Flessner RM, Sullivan SP, Prausnitz MR, Lynn DM. Layer-by-layer assembly of DNA- and protein-containing films on microneedles for drug delivery to the skin. Biomacromolecules. 11: 3136-43. PMID 20942396 DOI: 10.1021/bm1009443  0.84
2010 Buck ME, Lynn DM. Free-standing and reactive thin films fabricated by covalent layer-by-layer assembly and subsequent lift-off of azlactone-containing polymer multilayers. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 16134-40. PMID 20857952 DOI: 10.1021/la103009a  0.84
2010 Karlsson AJ, Flessner RM, Gellman SH, Lynn DM, Palecek SP. Polyelectrolyte multilayers fabricated from antifungal β-peptides: design of surfaces that exhibit antifungal activity against Candida albicans. Biomacromolecules. 11: 2321-8. PMID 20831274 DOI: 10.1021/bm100424s  0.84
2010 Sun B, Lynn DM. Release of DNA from polyelectrolyte multilayers fabricated using 'charge-shifting' cationic polymers: tunable temporal control and sequential, multi-agent release. Journal of Controlled Release : Official Journal of the Controlled Release Society. 148: 91-100. PMID 20678530 DOI: 10.1016/j.jconrel.2010.07.112  0.84
2010 Kinsinger MI, Buck ME, Abbott NL, Lynn DM. Immobilization of polymer-decorated liquid crystal droplets on chemically tailored surfaces. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 10234-42. PMID 20405867 DOI: 10.1021/la100376u  0.84
2010 Buck ME, Lynn DM. Functionalization of fibers using azlactone-containing polymers: layer-by-layer fabrication of reactive thin films on the surfaces of hair and cellulose-based materials. Acs Applied Materials & Interfaces. 2: 1421-9. PMID 20402471 DOI: 10.1021/am1000882  0.84
2010 Sun B, Liu X, Buck ME, Lynn DM. Azlactone-functionalized polymers as reactive templates for parallel polymer synthesis: synthesis and screening of a small library of cationic polymers in the context of DNA delivery. Chemical Communications (Cambridge, England). 46: 2016-8. PMID 20221477 DOI: 10.1039/b921664b  0.84
2010 Buck ME, Lynn DM. Reactive layer-by-layer assembly of suspended thin films and semipermeable membranes at interfaces created between aqueous and organic phases. Advanced Materials (Deerfield Beach, Fla.). 22: 994-8. PMID 20217827 DOI: 10.1002/adma.200903054  0.84
2010 Fredin NJ, Flessner RM, Jewell CM, Bechler SL, Buck ME, Lynn DM. Characterization of nanoscale transformations in polyelectrolyte multilayers fabricated from plasmid DNA using laser scanning confocal microscopy in combination with atomic force microscopy. Microscopy Research and Technique. 73: 834-44. PMID 20155860 DOI: 10.1002/jemt.20830  0.84
2010 Kinsinger MI, Buck ME, Meli MV, Abbott NL, Lynn DM. Langmuir films of flexible polymers transferred to aqueous/liquid crystal interfaces induce uniform azimuthal alignment of the liquid crystal. Journal of Colloid and Interface Science. 341: 124-35. PMID 19836025 DOI: 10.1016/j.jcis.2009.09.026  0.84
2010 Kinsinger MI, Lynn DM, Abbott NL. Nematic ordering drives the phase separation of mixed monolayers containing phospholipids modified with poly(ethylene glycol) at aqueous-liquid crystal interfaces Soft Matter. 6: 4095-4104. DOI: 10.1039/c0sm00080a  0.84
2009 Buck ME, Breitbach AS, Belgrade SK, Blackwell HE, Lynn DM. Chemical modification of reactive multilayered films fabricated from poly(2-alkenyl azlactone)s: design of surfaces that prevent or promote mammalian cell adhesion and bacterial biofilm growth. Biomacromolecules. 10: 1564-74. PMID 19438231 DOI: 10.1021/bm9001552  0.84
2009 Fredin NJ, Broderick AH, Buck ME, Lynn DM. Nanoimprinted thin films of reactive, azlactone-containing polymers: combining methods for the topographic patterning of cell substrates with opportunities for facile post-fabrication chemical functionalization. Biomacromolecules. 10: 994-1003. PMID 19290643 DOI: 10.1021/bm900045c  0.84
2009 Saurer EM, Jewell CM, Kuchenreuther JM, Lynn DM. Assembly of erodible, DNA-containing thin films on the surfaces of polymer microparticles: toward a layer-by-layer approach to the delivery of DNA to antigen-presenting cells. Acta Biomaterialia. 5: 913-24. PMID 18838346 DOI: 10.1016/j.actbio.2008.08.022  0.84
2008 Jewell CM, Lynn DM. Surface-Mediated Delivery of DNA: Cationic Polymers Take Charge. Current Opinion in Colloid & Interface Science. 13: 395-402. PMID 19956345 DOI: 10.1016/j.cocis.2008.03.005  0.84
2008 Liu X, Zhang J, Lynn DM. Ultrathin Multilayered Films that Promote the Release of Two DNA Constructs with Separate and Distinct Release Profiles. Advanced Materials (Deerfield Beach, Fla.). 20: 4148-4153. PMID 19890379 DOI: 10.1002/adma.200  0.84
2008 Liu X, Zhang J, Lynn DM. Polyelectrolyte Multilayers Fabricated from 'Charge-Shifting' Anionic Polymers: A New Approach to Controlled Film Disruption and the Release of Cationic Agents from Surfaces. Soft Matter. 4: 1688-1695. PMID 19122876 DOI: 10.1039/b804953j  0.84
2008 Kinsinger MI, Buck ME, Campos F, Lynn DM, Abbott NL. Dynamic ordering transitions of liquid crystals driven by interfacial complexes formed between polyanions and amphiphilic polyamines. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 13231-6. PMID 18991416 DOI: 10.1021/la803376u  0.84
2008 Jewell CM, Hays ME, Kondo Y, Abbott NL, Lynn DM. Chemical activation of lipoplexes formed from DNA and a redox-active, ferrocene-containing cationic lipid. Bioconjugate Chemistry. 19: 2120-8. PMID 18831573 DOI: 10.1021/bc8002138  0.84
2008 Liu X, Yang JW, Lynn DM. Addition of "charge-shifting" side chains to linear poly(ethyleneimine) enhances cell transfection efficiency. Biomacromolecules. 9: 2063-71. PMID 18564876 DOI: 10.1021/bm800291v  0.84
2008 Pizzey CL, Jewell CM, Hays ME, Lynn DM, Abbott NL, Kondo Y, Golan S, Talmon Y. Characterization of the nanostructure of complexes formed by a redox-active cationic lipid and DNA. The Journal of Physical Chemistry. B. 112: 5849-57. PMID 18419168 DOI: 10.1021/jp7103903  0.84
2008 Jewell CM, Lynn DM. Multilayered polyelectrolyte assemblies as platforms for the delivery of DNA and other nucleic acid-based therapeutics. Advanced Drug Delivery Reviews. 60: 979-99. PMID 18395291 DOI: 10.1016/j.addr.2008.02.010  0.84
2007 Zhang J, Fredin NJ, Lynn DM. Apparent dewetting of ultrathin multilayered polyelectrolyte films incubated in aqueous environments. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 11603-10. PMID 17918976 DOI: 10.1021/la701720k  0.84
2007 Zhang J, Montañez SI, Jewell CM, Lynn DM. Multilayered films fabricated from plasmid DNA and a side-chain functionalized poly(beta-amino ester): surface-type erosion and sequential release of multiple plasmid constructs from surfaces. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 11139-46. PMID 17887783 DOI: 10.1021/la702021s  0.84
2007 Hays ME, Jewell CM, Kondo Y, Lynn DM, Abbott NL. Lipoplexes formed by DNA and ferrocenyl lipids: effect of lipid oxidation state on size, internal dynamics, and zeta-potential. Biophysical Journal. 93: 4414-24. PMID 17720731 DOI: 10.1529/biophysj.107.107094  0.84
2007 Sun B, Jewell CM, Fredin NJ, Lynn DM. Assembly of multilayered films using well-defined, end-labeled poly(acrylic acid): influence of molecular weight on exponential growth in a synthetic weak polyelectrolyte system. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 8452-9. PMID 17616162 DOI: 10.1021/la7010875  0.84
2007 Hays ME, Jewell CM, Lynn DM, Abbott NL. Reversible condensation of DNA using a redox-active surfactant. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 5609-14. PMID 17428073 DOI: 10.1021/la0700319  0.84
2007 Fredin NJ, Zhang J, Lynn DM. Nanometer-scale decomposition of ultrathin multilayered polyelectrolyte films. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 2273-6. PMID 17309197 DOI: 10.1021/la0624182  0.84
2007 Jewell CM, Fuchs SM, Flessner RM, Raines RT, Lynn DM. Multilayered films fabricated from an oligoarginine-conjugated protein promote efficient surface-mediated protein transduction. Biomacromolecules. 8: 857-63. PMID 17269822 DOI: 10.1021/bm0609442  0.84
2007 Lynn DM. Peeling back the layers: Controlled erosion and triggered disassembly of multilayered polyelectrolyte thin films Advanced Materials. 19: 4118-4130. DOI: 10.1002/adma.200701748  0.84
2007 Zhang J, Lynn DM. Ultrathin multilayered films assembled from "charge-shifting" cationic polymers: Extended, long-term release of plasmid DNA from surfaces Advanced Materials. 19: 4218-4223. DOI: 10.1002/adma.200701028  0.84
2007 Buck ME, Zhang J, Lynn DM. Layer-by-layer assembly of reactive ultrathin films mediated by click-type reactions of poly(2-alkenyl azlactone)s Advanced Materials. 19: 3951-3955. DOI: 10.1002/adma.200700822  0.84
2007 Kinsinger MI, Sun B, Abbott NL, Lynn DM. Reversible control of ordering transitions at aqueous/liquid crystal interfaces using functional amphiphilic polymers Advanced Materials. 19: 4208-4212. DOI: 10.1002/adma.200700718  0.84
2006 Zhang J, Lynn DM. Multilayered Films Fabricated from Combinations of Degradable Polyamines: Tunable Erosion and Release of Anionic Polyelectrolytes. Macromolecules. 39: 8928-8935. PMID 19043614 DOI: 10.1021/ma061815g  0.84
2006 Jewell CM, Zhang J, Fredin NJ, Wolff MR, Hacker TA, Lynn DM. Release of plasmid DNA from intravascular stents coated with ultrathin multilayered polyelectrolyte films. Biomacromolecules. 7: 2483-91. PMID 16961308 DOI: 10.1021/bm0604808  0.84
2006 Berry D, Lynn DM, Berry E, Sasisekharan R, Langer R. Heparin localization and fine structure regulate Burkitt's lymphoma growth. Biochemical and Biophysical Research Communications. 348: 850-6. PMID 16904641 DOI: 10.1016/j.bbrc.2006.07.128  0.84
2006 Wood KC, Chuang HF, Batten RD, Lynn DM, Hammond PT. Controlling interlayer diffusion to achieve sustained, multiagent delivery from layer-by-layer thin films. Proceedings of the National Academy of Sciences of the United States of America. 103: 10207-12. PMID 16801543 DOI: 10.1073/pnas.0602884103  0.84
2006 Jewell CM, Hays ME, Kondo Y, Abbott NL, Lynn DM. Ferrocene-containing cationic lipids for the delivery of DNA: oxidation state determines transfection activity. Journal of Controlled Release : Official Journal of the Controlled Release Society. 112: 129-38. PMID 16529838 DOI: 10.1016/j.jconrel.2006.01.014  0.84
2006 Zhang J, Fredin NJ, Janz JF, Sun B, Lynn DM. Structure/property relationships in erodible multilayered films: influence of polycation structure on erosion profiles and the release of anionic polyelectrolytes. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 239-45. PMID 16378427 DOI: 10.1021/la052360b  0.84
2006 Lynn DM. Layers of opportunity: Nanostructured polymer assemblies for the delivery of macromolecular therapeutics Soft Matter. 2: 269-273. DOI: 10.1039/b517860f  0.84
2006 Zhang J, Fredin NJ, Lynn DM. Erosion of multilayered films fabricated from degradable polyamines: Characterization and evidence in support of a mechanism that involves polymer hydrolysis Journal of Polymer Science, Part a: Polymer Chemistry. 44: 5161-5173. DOI: 10.1002/pola.21613  0.84
2005 Little SR, Lynn DM, Puram SV, Langer R. Formulation and characterization of poly (beta amino ester) microparticles for genetic vaccine delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 107: 449-62. PMID 16112767 DOI: 10.1016/j.jconrel.2005.04.022  0.84
2005 Abbott NL, Jewell CM, Hays ME, Kondo Y, Lynn DM. Ferrocene-containing cationic lipids: influence of redox state on cell transfection. Journal of the American Chemical Society. 127: 11576-7. PMID 16104714 DOI: 10.1021/ja054038t  0.84
2005 Jewell CM, Zhang J, Fredin NJ, Lynn DM. Multilayered polyelectrolyte films promote the direct and localized delivery of DNA to cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 106: 214-23. PMID 15979188 DOI: 10.1016/j.jconrel.2005.04.014  0.84
2005 Fredin NJ, Zhang J, Lynn DM. Surface analysis of erodible multilayered polyelectrolyte films: nanometer-scale structure and erosion profiles. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 5803-11. PMID 15952826 DOI: 10.1021/la050596+  0.84
2005 Wood KC, Boedicker JQ, Lynn DM, Hammond PT. Tunable drug release from hydrolytically degradable layer-by-layer thin films. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 1603-9. PMID 15697314 DOI: 10.1021/la0476480  0.84
2005 Liu X, Yang JW, Miller AD, Nack EA, Lynn DM. Charge-shifting cationic polymers that promote self-assembly and self-disassembly with DNA Macromolecules. 38: 7907-7914. DOI: 10.1021/ma051270a  0.84
2005 Fredin NJ, Zhang J, Lynn DM. Nanometer-scale structure and erosion profiles of erodible multilayered polyelectrolyte films Aiche Annual Meeting, Conference Proceedings. 4176.  0.84
2005 Jewell CM, Zhang J, Fredin NJ, Lynn DM. Multilayered polyelectrolyte films for the localized delivery of DNA to cells Aiche Annual Meeting, Conference Proceedings. 4532.  0.84
2004 Zhang J, Chua LS, Lynn DM. Multilayered thin films that sustain the release of functional DNA under physiological conditions. Langmuir : the Acs Journal of Surfaces and Colloids. 20: 8015-21. PMID 15350066 DOI: 10.1021/la048888i  0.84
2004 Little SR, Lynn DM, Ge Q, Anderson DG, Puram SV, Chen J, Eisen HN, Langer R. Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proceedings of the National Academy of Sciences of the United States of America. 101: 9534-9. PMID 15210954 DOI: 10.1073/pnas.0403549101  0.84
2004 Berry D, Lynn DM, Sasisekharan R, Langer R. Poly(beta-amino ester)s promote cellular uptake of heparin and cancer cell death. Chemistry & Biology. 11: 487-98. PMID 15123243 DOI: 10.1016/j.chembiol.2004.03.023  0.84
2004 Gelman MA, Weisblum B, Lynn DM, Gellman SH. Biocidal activity of polystyrenes that are cationic by virtue of protonation. Organic Letters. 6: 557-60. PMID 14961622 DOI: 10.1021/ol036341+  0.84
2003 Akinc A, Anderson DG, Lynn DM, Langer R. Synthesis of poly(beta-amino ester)s optimized for highly effective gene delivery. Bioconjugate Chemistry. 14: 979-88. PMID 13129402 DOI: 10.1021/bc034067y  0.84
2003 Anderson DG, Lynn DM, Langer R. Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery. Angewandte Chemie (International Ed. in English). 42: 3153-8. PMID 12866105 DOI: 10.1002/anie.200351244  0.84
2003 Akinc A, Lynn DM, Anderson DG, Langer R. Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery. Journal of the American Chemical Society. 125: 5316-23. PMID 12720443 DOI: 10.1021/ja034429c  0.84
2003 Potineni A, Lynn DM, Langer R, Amiji MM. Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive biodegradable system for paclitaxel delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 86: 223-34. PMID 12526819 DOI: 10.1016/S0168-3659(02)00374-7  0.84
2002 Zelikin AN, Lynn DM, Farhadi J, Martin I, Shastri V, Langer R. Erodible conducting polymers for potential biomedical applications. Angewandte Chemie (International Ed. in English). 41: 141-4. PMID 12491465 DOI: 10.1002/1521-3773(20020104)41:1<141::AID-ANIE141>3.0.CO;2-V  0.84
2002 Vázquez E, Dewitt DM, Hammond PT, Lynn DM. Construction of hydrolytically-degradable thin films via layer-by-layer deposition of degradable polyelectrolytes. Journal of the American Chemical Society. 124: 13992-3. PMID 12440887 DOI: 10.1021/ja026405w  0.84
2002 LaVan DA, Lynn DM, Langer R. Moving smaller in drug discovery and delivery. Nature Reviews. Drug Discovery. 1: 77-84. PMID 12119612 DOI: 10.1038/nrd707  0.84
2001 Lynn DM, Anderson DG, Putnam D, Langer R. Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library. Journal of the American Chemical Society. 123: 8155-6. PMID 11506588 DOI: 10.1021/ja016288p  0.84
2001 Lynn DM, Grubbs RH. Novel reactivity of ruthenium alkylidenes in protic solvents: degenerate alkylidene proton exchange. Journal of the American Chemical Society. 123: 3187-93. PMID 11457052 DOI: 10.1021/ja0020299  1
2001 Lynn DM, Amiji MM, Langer R. pH-Responsive Polymer Microspheres: Rapid Release of Encapsulated Material within the Range of Intracellular pH Financial support was provided by the NSF (Cooperative Agreement No. ECC9843342 to the MIT Biotechnology Process Engineering Center), the NIH (GM26698), and the Department of the Army (Cooperative Agreement DAMD 17-99-2-9-001 to the Center for Innovative Minimally Invasive Therapy). D.M.L. wishes to thank the NIH for a Postdoctoral Fellowship (NRSA Fellowship No. 1 F32 GM20227-01). Scanning electron microscopy and confocal microscopy images were acquired by William Fowle at the Northeastern University Center for Electron Microscopy. Dr. David Putnam, David Ting, and Tommy Thomas are thanked for helpful discussions. Angewandte Chemie (International Ed. in English). 40: 1707-1710. PMID 11353487 DOI: 10.1002/1521-3773(20010504)40:9<1707::AID-ANIE17070>3.0.CO;2-F  0.84
2000 Lynn DM, Langer R. Degradable poly(β-amino esters): Synthesis, characterization, and self-assembly with plasmid DNA Journal of the American Chemical Society. 122: 10761-10768. DOI: 10.1021/ja0015388  0.84
2000 Lynn DM, Mohr B, Grubbs RH, Henling LM, Day MW. Water-soluble ruthenium alkylidenes: Synthesis, characterization, and application to olefin metathesis in protic solvents Journal of the American Chemical Society. 122: 6601-6609. DOI: 10.1021/ja0003167  1
1998 Kirkland TA, Lynn DM, Grubbs RH. Ring-closing metathesis in methanol and water Journal of Organic Chemistry. 63: 9904-9909. DOI: 10.1021/jo981678o  1
1998 Lynn DM, Mohr B, Grubbs RH. Living ring-opening metathesis polymerization in water [5] Journal of the American Chemical Society. 120: 1627-1628. DOI: 10.1021/ja9736323  1
1998 Lynn DM, Mohr B, Grubbs RH. Living ring-opening metathesis polymerization in water via activation of water-soluble ruthenium alkylidenes American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 39: 278-279.  1
1996 Mohr B, Lynn DM, Grubbs RH. Synthesis of water-soluble, aliphatic phosphines and their application to well-defined ruthenium olefin metathesis catalysts Organometallics. 15: 4317-4325.  1
1996 Lynn DM, Kanaoka S, Grubbs RH. Living ring-opening metathesis polymerization in aqueous media catalyzed by well-defined ruthenium carbene complexes Journal of the American Chemical Society. 118: 784-789.  1
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