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Nancy Y. Ip, Ph.D. - Publications

Affiliations: 
Dean of Science Hong Kong Univ. of Sci. & Technology 
Area:
Neuroscience

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhou X, Chen Y, Ip FCF, Lai NCH, Li YYT, Jiang Y, Zhong H, Chen Y, Zhang Y, Ma S, Lo RMN, Cheung K, Tong EPS, Ko H, Shoai M, ... ... Ip NY, et al. Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12074. PMID 32775599 DOI: 10.1002/Dad2.12074  0.415
2020 Lau SF, Chen C, Fu WY, Qu JY, Cheung TH, Fu AKY, Ip NY. IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer's Disease. Cell Reports. 31: 107530. PMID 32320664 DOI: 10.1016/J.Celrep.2020.107530  0.738
2019 Chen Y, Xu J, Zhou X, Liu S, Zhang Y, Ma S, Fu AKY, Ip NY, Chen Y. Changes of protein phosphorylation are associated with synaptic functions during the early stage of Alzheimer's disease. Acs Chemical Neuroscience. PMID 31424205 DOI: 10.1021/Acschemneuro.9B00190  0.361
2019 Su YT, Lau SF, Ip JPK, Cheung K, Cheung THT, Fu AKY, Ip NY. α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31209021 DOI: 10.1073/Pnas.1903891116  0.736
2019 Chen WW, Fu WY, Su YT, Fang WQ, Fu AKY, Ip NY. Increased Axin expression enhances adult hippocampal neurogenesis and exerts an antidepressant effect. Scientific Reports. 9: 1190. PMID 30718786 DOI: 10.1038/S41598-018-38103-3  0.32
2019 Chen Y, Xu J, Zhou X, Liu S, Zhang Y, Ma S, Fu AKY, Ip NY, Chen Y. P4‐128: Identification Of Protein Phosphorylation Associated With Aberrant Synaptic Function In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3789  0.302
2018 Chen Y, Fu AKY, Ip NY. Synaptic dysfunction in Alzheimer's disease: Mechanisms and therapeutic strategies. Pharmacology & Therapeutics. PMID 30439458 DOI: 10.1016/J.Pharmthera.2018.11.006  0.301
2018 Gu S, Fu WY, Fu AKY, Tong EPS, Ip FCF, Huang X, Ip NY. Identification of new EphA4 inhibitors by virtual screening of FDA-approved drugs. Scientific Reports. 8: 7377. PMID 29743517 DOI: 10.1038/S41598-018-25790-1  0.33
2018 Cui Q, Li Q, Geng H, Chen L, Ip NY, Ke Y, Yung WH. Dopamine receptors mediate strategy abandoning via modulation of a specific prelimbic cortex-nucleus accumbens pathway in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735678 DOI: 10.1073/Pnas.1717106115  0.321
2018 Lai KO, Ip NY. Methods to Study the Signal Transduction of the Surface Receptor Tyrosine Kinase TrkB in Neurons. Methods in Molecular Biology (Clifton, N.J.). 1722: 211-222. PMID 29264808 DOI: 10.1007/978-1-4939-7553-2_14  0.353
2017 Fu AKY, Ip NY. Homeostatic Scaling of AMPA Receptors by Semaphorin. Neuron. 96: 955-958. PMID 29216456 DOI: 10.1016/J.Neuron.2017.11.025  0.324
2017 Huang H, Lin X, Liang Z, Zhao T, Du S, Loy MMT, Lai KO, Fu AKY, Ip NY. Cdk5-dependent phosphorylation of liprinα1 mediates neuronal activity-dependent synapse development. Proceedings of the National Academy of Sciences of the United States of America. PMID 28760951 DOI: 10.1073/Pnas.1708240114  0.421
2017 Fu AK, Ip NY. Regulation of postsynaptic signaling in structural synaptic plasticity. Current Opinion in Neurobiology. 45: 148-155. PMID 28600964 DOI: 10.1016/J.Conb.2017.05.016  0.309
2016 Shen Y, Tian M, Zheng Y, Gong F, Fu AK, Ip NY. Stimulation of the Hippocampal POMC/MC4R Circuit Alleviates Synaptic Plasticity Impairment in an Alzheimer's Disease Model. Cell Reports. 17: 1819-1831. PMID 27829153 DOI: 10.1016/J.Celrep.2016.10.043  0.518
2016 Tang G, Liu X, Ma N, Huang X, Wu ZL, Zhang W, Wang Y, Zhao BX, Wang ZY, Ip FC, Ip NY, Ye WC, Shi L, Chen WM. Design and synthesis of dimeric securinine analogs with neuritogenic activities. Acs Chemical Neuroscience. PMID 27467236 DOI: 10.1021/Acschemneuro.6B00188  0.407
2016 Fu AK, Hung KW, Yuen MY, Zhou X, Mak DS, Chan IC, Cheung TH, Zhang B, Fu WY, Liew FY, Ip NY. IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091974 DOI: 10.1073/Pnas.1604032113  0.308
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Ip NY, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.362
2015 Liang Z, Ye T, Zhou X, Lai KO, Fu AK, Ip NY. Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15127-34. PMID 26558783 DOI: 10.1523/JNEUROSCI.1443-15.2015  0.35
2015 Chen Y, Liang Z, Fei E, Chen Y, Zhou X, Fang W, Fu WY, Fu AK, Ip NY. Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling. Plos One. 10: e0133115. PMID 26204446 DOI: 10.1371/Journal.Pone.0133115  0.403
2015 Ye T, Fu AK, Ip NY. Emerging roles of Axin in cerebral cortical development. Frontiers in Cellular Neuroscience. 9: 217. PMID 26106297 DOI: 10.3389/Fncel.2015.00217  0.413
2015 Yoshii A, Constantine-Paton M, Ip NY. Editorial: Cell and molecular signaling, and transport pathways involved in growth factor control of synaptic development and function. Frontiers in Synaptic Neuroscience. 7: 8. PMID 26089796 DOI: 10.3389/Fnsyn.2015.00008  0.399
2015 Lai KO, Liang Z, Fei E, Huang H, Ip NY. Cyclin-dependent Kinase 5 (Cdk5)-dependent Phosphorylation of p70 Ribosomal S6 Kinase 1 (S6K) Is Required for Dendritic Spine Morphogenesis. The Journal of Biological Chemistry. 290: 14637-46. PMID 25903132 DOI: 10.1074/jbc.M114.627117  0.338
2015 Zhao XS, Fu WY, Hung KW, Chien WW, Li Z, Fu AK, Ip NY. NRC-interacting factor directs neurite outgrowth in an activity-dependent manner. Neuroscience. 289: 207-13. PMID 25573434 DOI: 10.1016/J.Neuroscience.2014.12.041  0.447
2014 Fang WQ, Chen WW, Jiang L, Liu K, Yung WH, Fu AK, Ip NY. Overproduction of upper-layer neurons in the neocortex leads to autism-like features in mice. Cell Reports. 9: 1635-43. PMID 25466248 DOI: 10.1016/J.Celrep.2014.11.003  0.406
2014 Li S, He Q, Wang H, Tang X, Ho KW, Gao X, Zhang Q, Shen Y, Cheung A, Wong F, Wong YH, Ip NY, Jiang L, Yung WH, Liu K. Injured adult retinal axons with Pten and Socs3 co-deletion reform active synapses with suprachiasmatic neurons. Neurobiology of Disease. 73: 366-376. PMID 25448764 DOI: 10.1016/J.Nbd.2014.09.019  0.357
2014 Zhao XS, Fu WY, Chien WW, Li Z, Fu AK, Ip NY. p35 regulates the CRM1-dependent nucleocytoplasmic shuttling of nuclear hormone receptor coregulator-interacting factor 1 (NIF-1). Plos One. 9: e110584. PMID 25329792 DOI: 10.1371/Journal.Pone.0110584  0.385
2014 Ye T, Ip JP, Fu AK, Ip NY. Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex. Nature Communications. 5: 4826. PMID 25189171 DOI: 10.1038/Ncomms5826  0.766
2014 Ip FC, Ng YP, An HJ, Dai Y, Pang HH, Hu YQ, Chin AC, Harley CB, Wong YH, Ip NY. Cycloastragenol is a potent telomerase activator in neuronal cells: implications for depression management. Neuro-Signals. 22: 52-63. PMID 25095809 DOI: 10.1159/000365290  0.403
2014 Tang J, Ip JP, Ye T, Ng YP, Yung WH, Wu Z, Fang W, Fu AK, Ip NY. Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7425-36. PMID 24872548 DOI: 10.1523/Jneurosci.5449-13.2014  0.778
2014 Ip JPK, Fu AKY, Ip NY. CRMP2: Functional roles in neural development and therapeutic potential in neurological diseases Neuroscientist. 20: 589-598. PMID 24402611 DOI: 10.1177/1073858413514278  0.765
2013 Fang WQ, Chen WW, Fu AK, Ip NY. Axin directs the amplification and differentiation of intermediate progenitors in the developing cerebral cortex. Neuron. 79: 665-79. PMID 23972596 DOI: 10.1016/J.Neuron.2013.06.017  0.39
2013 Xiao Y, Peng Y, Wan J, Tang G, Chen Y, Tang J, Ye WC, Ip NY, Shi L. The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics. The Journal of Biological Chemistry. 288: 20034-45. PMID 23720743 DOI: 10.1074/Jbc.M113.458612  0.437
2013 Shen Y, Fu WY, Cheng EYL, Fu AKY, Ip NY. Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism Journal of Neuroscience. 33: 464-472. PMID 23303927 DOI: 10.1523/Jneurosci.3282-12.2013  0.362
2013 Fu AKY, Hung KW, Wong HHW, Fu WY, Ip NY. Cdk5 phosphorylates a component of the HDAC complex and regulates histone acetylation during neuronal cell death Neurosignals. 21: 55-60. PMID 22398430 DOI: 10.1159/000335158  0.771
2012 Ye T, Fu AKY, Ip NY. Cyclin-Dependent Kinase 5 in Axon Growth and Regeneration International Review of Neurobiology. 105: 91-115. PMID 23206597 DOI: 10.1016/B978-0-12-398309-1.00006-8  0.343
2012 Lai KO, Wong AS, Cheung MC, Xu P, Liang Z, Lok KC, Xie H, Palko ME, Yung WH, Tessarollo L, Cheung ZH, Ip NY. TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory. Nature Neuroscience. 15: 1506-15. PMID 23064382 DOI: 10.1038/nn.3237  0.514
2012 Chen Y, Fu WY, Ip JP, Ye T, Fu AK, Chao MV, Ip NY. Ankyrin repeat-rich membrane spanning protein (kidins220) is required for neurotrophin and ephrin receptor-dependent dendrite development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8263-9. PMID 22699907 DOI: 10.1523/Jneurosci.1264-12.2012  0.773
2012 Cheung ZH, Ip NY. Cdk5: A multifaceted kinase in neurodegenerative diseases Trends in Cell Biology. 22: 169-175. PMID 22189166 DOI: 10.1016/J.Tcb.2011.11.003  0.349
2012 Huang Y, Ko H, Cheung ZH, Yung KK, Yao T, Wang JJ, Morozov A, Ke Y, Ip NY, Yung WH. Dual actions of brain-derived neurotrophic factor on GABAergic transmission in cerebellar Purkinje neurons. Experimental Neurology. 233: 791-8. PMID 22178325 DOI: 10.1016/J.Expneurol.2011.11.043  0.524
2012 Ip JP, Shi L, Chen Y, Itoh Y, Fu WY, Betz A, Yung WH, Gotoh Y, Fu AK, Ip NY. α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2. Nature Neuroscience. 15: 39-47. PMID 22138645 DOI: 10.1038/Nn.2972  0.758
2012 Chen Y, Fu AKY, Ip NY. Eph receptors at synapses: Implications in neurodegenerative diseases Cellular Signalling. 24: 606-611. PMID 22120527 DOI: 10.1016/J.Cellsig.2011.11.016  0.325
2012 Yung LY, Lam WS, Ho MK, Hu Y, Ip FC, Pang H, Chin AC, Harley CB, Ip NY, Wong YH. Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types. Planta Medica. 78: 115-21. PMID 22083896 DOI: 10.1055/S-0031-1280346  0.355
2012 Fitzgerald JC, Camprubi MD, Dunn L, Wu HC, Ip NY, Kruger R, Martins LM, Wood NW, Plun-Favreau H. Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function Cell Death and Differentiation. 19: 257-266. PMID 21701498 DOI: 10.1038/Cdd.2011.90  0.339
2011 Fang WQ, Ip JPK, Li R, Ng YP, Lin SC, Chen Y, Fu AKY, Ip NY. Cdk5-mediated phosphorylation of Axin directs axon formation during cerebral cortex development Journal of Neuroscience. 31: 13613-13624. PMID 21940452 DOI: 10.1523/Jneurosci.3120-11.2011  0.743
2011 Zhang XQ, Ip FCF, Zhang DM, Chen LX, Zhang W, Li YL, Ip NY, Ye WC. Triterpenoids with neurotrophic activity from Ganoderma lucidum Natural Product Research. 25: 1607-1613. PMID 21671206 DOI: 10.1080/14786419.2010.496367  0.353
2011 Wong AS, Lee RH, Cheung AY, Yeung PK, Chung SK, Cheung ZH, Ip NY. Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease. Nature Cell Biology. 13: 568-79. PMID 21499257 DOI: 10.1038/NCB0611-734D  0.411
2011 Farghaian H, Chen Y, Fu AWY, Fu AKY, Ip JPK, Ip NY, Turnley AM, Cole AR. Scapinin-induced inhibition of axon elongation is attenuated by phosphorylation and translocation to the cytoplasm Journal of Biological Chemistry. 286: 19724-19734. PMID 21487013 DOI: 10.1074/Jbc.M110.205781  0.751
2011 Fu WY, Cheng K, Fu AKY, Ip NY. Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development Neuroscience. 180: 353-359. PMID 21335063 DOI: 10.1016/J.Neuroscience.2011.02.024  0.462
2011 Cheung ZH, Ip NY. From understanding synaptic plasticity to the development of cognitive enhancers International Journal of Neuropsychopharmacology. 14: 1247-1256. PMID 21208502 DOI: 10.1017/S1461145710001537  0.32
2011 Fu AKY, Hung KW, Fu WY, Shen C, Chen Y, Xia J, Lai KO, Ip NY. APCCdh1 mediates EphA4-dependent downregulation of AMPA receptors in homeostatic plasticity Nature Neuroscience. 14: 181-191. PMID 21186356 DOI: 10.1038/Nn.2715  0.418
2010 Shi L, Fu AK, Ip NY. Multiple roles of the Rho GEF ephexin1 in synapse remodeling. Communicative & Integrative Biology. 3: 622-4. PMID 21331259 DOI: 10.4161/Cib.3.6.13481  0.312
2010 Zhang P, Yu PC, Tsang AH, Chen Y, Fu AK, Fu WY, Chung KK, Ip NY. S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14366-70. PMID 20980593 DOI: 10.1523/Jneurosci.3899-10.2010  0.45
2010 Poore CP, Sundaram JR, Pareek TK, Fu A, Amin N, Mohamed NE, Zheng YL, Goh AX, Lai MK, Ip NY, Pant HC, Kesavapany S. Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8457-67. PMID 20573893 DOI: 10.1523/Jneurosci.6062-09.2010  0.381
2010 Ou CY, Poon VY, Maeder CI, Watanabe S, Lehrman EK, Fu AK, Park M, Fu WY, Jorgensen EM, Ip NY, Shen K. Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components. Cell. 141: 846-58. PMID 20510931 DOI: 10.1016/J.Cell.2010.04.011  0.373
2010 Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY. Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6873-81. PMID 20484629 DOI: 10.1523/Jneurosci.0519-10.2010  0.399
2010 Hu Y, Ip FCF, Fu G, Pang H, Ye W, Ip NY. Dammarane saponins from Gynostemma pentaphyllum Phytochemistry. 71: 1149-1157. PMID 20483436 DOI: 10.1016/J.Phytochem.2010.04.003  0.367
2010 Ng YP, Lee SM, Cheung TK, Nicholls JM, Peiris JS, Ip NY. Avian influenza H5N1 virus induces cytopathy and proinflammatory cytokine responses in human astrocytic and neuronal cell lines. Neuroscience. 168: 613-23. PMID 20398740 DOI: 10.1016/J.Neuroscience.2010.04.013  0.328
2010 Shi L, Butt B, Ip FC, Dai Y, Jiang L, Yung WH, Greenberg ME, Fu AK, Ip NY. Ephexin1 is required for structural maturation and neurotransmission at the neuromuscular junction. Neuron. 65: 204-16. PMID 20152127 DOI: 10.1016/J.Neuron.2010.01.012  0.308
2010 Fu G, Ip FCF, Pang H, Ip NY. New secoiridoid glucosides from ligustrum lucidum induce erk and creb phosphorylation in cultured cortical neurons Planta Medica. 76: 998-1003. PMID 20143293 DOI: 10.1055/S-0029-1240869  0.379
2009 Tso PH, Morris CJ, Yung LY, Ip NY, Wong YH. Multiple Gi proteins participate in nerve growth factor-induced activation of c-jun N-terminal kinases in PC12 cells Neurochemical Research. 34: 1101-1112. PMID 19009346 DOI: 10.1007/S11064-008-9880-9  0.357
2009 Cheung ZH, Ip NY. Endophilin B1. Guarding the gate to destruction Communicative and Integrative Biology. 2: 130-132. DOI: 10.4161/Cib.7745  0.364
2008 Chen Y, Fu AKY, Ip NY. Bidirectional signaling of ErbB and Eph receptors at synapses Neuron Glia Biology. 4: 211-221. PMID 19785921 DOI: 10.1017/S1740925X09990287  0.348
2008 Yung LY, Tso PH, Wu EHT, Yu JCH, Ip NY, Wong YH. Nerve growth factor-induced stimulation of p38 mitogen-activated protein kinase in PC12 cells is partially mediated via Gi/o proteins Cellular Signalling. 20: 1538-1544. PMID 18508236 DOI: 10.1016/J.Cellsig.2008.04.007  0.351
2008 Cheung ZH, Gong K, Ip NY. Cyclin-dependent kinase 5 supports neuronal survival through phosphorylation of Bcl-2 Journal of Neuroscience. 28: 4872-4877. PMID 18463240 DOI: 10.1523/Jneurosci.0689-08.2008  0.437
2007 Shi L, Fu WY, Hung KW, Porchetta C, Hall C, Fu AKY, Ip NY. α2-Chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse Proceedings of the National Academy of Sciences of the United States of America. 104: 16347-16352. PMID 17911252 DOI: 10.1073/Pnas.0706626104  0.333
2007 Nguyen C, Hosokawa T, Kuroiwa M, Ip NY, Nishi A, Hisanaga S, Bibb JA. Differential regulation of the Cdk5-dependent phosphorylation sites of inhibitor-1 and DARPP-32 by depolarization. Journal of Neurochemistry. 103: 1582-93. PMID 17868322 DOI: 10.1111/J.1471-4159.2007.04868.X  0.368
2007 Lok KC, Fu AKY, Ip FCF, Wong YH, Ip NY. NRG induces membrane targeting of Gαz in muscle: Implication in myogenesis Neuroreport. 18: 1433-1436. PMID 17712269 DOI: 10.1097/Wnr.0B013E3282E9A5B7  0.328
2007 Cheung ZH, Ip NY. The roles of cyclin-dependent kinase 5 in dendtrite and synapse development Biotechnology Journal. 2: 949-957. PMID 17526057 DOI: 10.1002/Biot.200700056  0.431
2007 Cheung ZH, Chin WH, Chen Y, Ng YP, Ip NY. Cdk5 is involved in BDNF-stimulated dendritic growth in hippocampal neurons Plos Biology. 5: e63. PMID 17341134 DOI: 10.1371/Journal.Pbio.0050063  0.468
2007 Fu WY, Chen Y, Sahin M, Zhao XS, Shi L, Bikoff JB, Lai KO, Yung WH, Fu AK, Greenberg ME, Ip NY. Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism. Nature Neuroscience. 10: 67-76. PMID 17143272 DOI: 10.1038/Nn1811  0.372
2006 Yu PN, Cheung ZH, Ip NY. STAT3 as a downstream mediator of Trk signaling and functions Journal of Biological Chemistry. 281: 15636-15644. PMID 16611639 DOI: 10.1074/Jbc.M601863200  0.4
2006 Cheung ZH, Fu AKY, Ip NY. Synaptic Roles of Cdk5: Implications in Higher Cognitive Functions and Neurodegenerative Diseases Neuron. 50: 13-18. PMID 16600851 DOI: 10.1016/J.Neuron.2006.02.024  0.337
2006 Liu Y, Cheng K, Gong K, Fu AKY, Ip NY. Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: Implications in the regulation of its hexamerization and exocytosis Journal of Biological Chemistry. 281: 9852-9858. PMID 16461345 DOI: 10.1074/jbc.M513496200  0.304
2005 Lo KY, Chin WH, Ng YP, Cheng AW, Cheung ZH, Ip NY. SLAM-associated protein as a potential negative regulator in Trk signaling Journal of Biological Chemistry. 280: 41744-41752. PMID 16223723 DOI: 10.1074/Jbc.M506554200  0.389
2005 Xu X, Fu AK, Ip FC, Wu CP, Duan S, Poo MM, Yuan XB, Ip NY. Agrin regulates growth cone turning of Xenopus spinal motoneurons. Development (Cambridge, England). 132: 4309-16. PMID 16141222 DOI: 10.1242/Dev.02016  0.416
2005 Luo S, Chen Y, Lai KO, Arévalo JC, Froehner SC, Adams ME, Chao MV, Ip NY. {alpha}-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner. The Journal of Cell Biology. 169: 813-24. PMID 15939763 DOI: 10.1083/Jcb.200412008  0.317
2005 Gu Z, Jiang Q, Fu AKY, Ip NY, Yan Z. Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex Journal of Neuroscience. 25: 4974-4984. PMID 15901778 DOI: 10.1523/Jneurosci.1086-05.2005  0.346
2004 Li Z, David G, Hung KW, DePinho RA, Fu AK, Ip NY. Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcription. The Journal of Biological Chemistry. 279: 54438-44. PMID 15489224 DOI: 10.1074/Jbc.M411002200  0.369
2004 Yu JCH, Min ZD, Ip NY. Melia toosendan regulates PC12 cell differentiation via the activation of protein kinase A and extracellular signal-regulated kinases Neurosignals. 13: 248-257. PMID 15305092 DOI: 10.1159/000079339  0.352
2004 Cheung ZH, Ip NY. Cdk5: Mediator of neuronal death and survival Neuroscience Letters. 361: 47-51. PMID 15135890 DOI: 10.1016/J.Neulet.2003.12.117  0.428
2004 Fu AKY, Fu WY, Ng AKY, Chien WWY, Ng YP, Wang JH, Ip NY. Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity Proceedings of the National Academy of Sciences of the United States of America. 101: 6728-6733. PMID 15096606 DOI: 10.1073/Pnas.0307606100  0.396
2003 Cheng K, Ip NY. Cdk5: A new player at synapses Neurosignals. 12: 180-190. PMID 14673204 DOI: 10.1159/000074619  0.434
2003 Xu Z, Lai KO, Zhou HM, Lin SC, Ip NY. Ephrin-B1 Reverse Signaling Activates JNK through a Novel Mechanism That Is Independent of Tyrosine Phosphorylation Journal of Biological Chemistry. 278: 24767-24775. PMID 12709432 DOI: 10.1074/Jbc.M302454200  0.357
2002 Cheng K, Li Z, Fu WY, Wang JH, Fu AKY, Ip NY. Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35 Journal of Biological Chemistry. 277: 31988-31993. PMID 12084709 DOI: 10.1074/Jbc.M201161200  0.35
2002 Fu WY, Wang JH, Ip NY. Expression of Cdk5 and its activators in NT2 cells during neuronal differentiation Journal of Neurochemistry. 81: 646-654. PMID 12065673 DOI: 10.1046/j.1471-4159.2002.00856.x  0.353
2001 Choi RC, Man ML, Ling KK, Ip NY, Simon J, Barnard EA, Tsim KW. Expression of the P2Y1 nucleotide receptor in chick muscle: its functional role in the regulation of acetylcholinesterase and acetylcholine receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9224-34. PMID 11717356 DOI: 10.1523/Jneurosci.21-23-09224.2001  0.322
2001 Cheung WM, Chu AH, Chu PW, Ip NY. Cloning and expression of a novel nuclear matrix-associated protein that is regulated during the retinoic acid-induced neuronal differentiation. The Journal of Biological Chemistry. 276: 17083-91. PMID 11278750 DOI: 10.1074/Jbc.M010802200  0.336
2000 Cheung WM, Hui WS, Chu PW, Chiu SW, Ip NY. Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells. Febs Letters. 486: 291-6. PMID 11119721 DOI: 10.1016/S0014-5793(00)02317-6  0.429
2000 Cheung WM, Chu PW, Lung CH, Ip NY. Expression of retinoid receptors during the retinoic acid-induced neuronal differentiation of human embryonal carcinoma cells. Journal of Neurochemistry. 75: 34-40. PMID 10854244 DOI: 10.1046/J.1471-4159.2000.0750034.X  0.376
2000 Xie P, Chan FSL, Ip NY, Leung MF. Induction of TrkA expression by differentiation inducers in human myeloid leukemia KG-1 cells Leukemia and Lymphoma. 36: 595-601. PMID 10784405 DOI: 10.3109/10428190009148408  0.311
2000 Ip NY, Zigmond RE. Synergistic effects of muscarinic agonists and secretin or vasoactive intestinal peptide on the regulation of tyrosine hydroxylase activity in sympathetic neurons. Journal of Neurobiology. 42: 14-21. PMID 10623897 DOI: 10.1002/(Sici)1097-4695(200001)42:1<14::Aid-Neu2>3.0.Co;2-Y  0.568
1998 Yang JF, Zhou H, Pun S, Ip NY, Peng HB, Tsim KW. Cloning of cDNAs encoding xenopus neuregulin: expression in myotomal muscle during embryo development. Brain Research. Molecular Brain Research. 58: 59-73. PMID 9685585 DOI: 10.1016/S0169-328X(98)00085-0  0.336
1998 Ip NY. The neurotrophins and neuropoietic cytokines: two families of growth factors acting on neural and hematopoietic cells. Annals of the New York Academy of Sciences. 840: 97-106. PMID 9629241 DOI: 10.1111/J.1749-6632.1998.Tb09553.X  0.399
1997 Cheung WMW, Chu AH, Ip NY. Identification of candidate genes induced by retinoic acid in embryonal carcinoma cells Journal of Neurochemistry. 68: 1882-1888. PMID 9109513 DOI: 10.1046/J.1471-4159.1997.68051882.X  0.307
1996 Lai KO, Glass DJ, Geis D, Yancopoulos GD, Ip NY. Structural determinants of Trk receptor specificities using BDNF-based neurotrophin chimeras Journal of Neuroscience Research. 46: 618-629. PMID 8951673 DOI: 10.1002/(Sici)1097-4547(19961201)46:5<618::Aid-Jnr10>3.0.Co;2-T  0.335
1996 Ip NY, Yancopoulos GD. The neurotrophins and CNTF: Two families of collaborative neurotrophic factors Annual Review of Neuroscience. 19: 491-515. PMID 8833452 DOI: 10.1146/Annurev.Ne.19.030196.002423  0.325
1996 Cheung WMW, Chu AH, Leung MF, Ip NY. Induction of trk receptors by retinoic acid in a human embryonal carcinoma cell line Neuroreport. 7: 1204-1208. PMID 8817533 DOI: 10.1097/00001756-199604260-00022  0.365
1995 Friedman B, Kleinfeld D, Ip NY, Verge VM, Moulton R, Boland P, Zlotchenko E, Lindsay RM, Liu L. BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1044-56. PMID 7869082 DOI: 10.1523/Jneurosci.15-02-01044.1995  0.357
1995 Wong V, Pearsall D, Arriaga R, Ip NY, Stahl N, Lindsay RM. Binding characteristics of ciliary neurotrophic factor to sympathetic neurons and neuronal cell lines. The Journal of Biological Chemistry. 270: 313-8. PMID 7814393 DOI: 10.1074/Jbc.270.1.313  0.402
1995 Conover JC, Erickson JT, Katz DM, Bianchi LM, Poueymirou WT, McClain J, Pan L, Helgren M, Ip NY, Boland P. Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4. Nature. 375: 235-8. PMID 7746324 DOI: 10.1038/375235A0  0.384
1995 DeChiara TM, Vejsada R, Poueymirou WT, Acheson A, Suri C, Conover JC, Friedman B, McClain J, Pan L, Stahl N, Ip NY, Yancopoulos GD. Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth. Cell. 83: 313-22. PMID 7585948 DOI: 10.1016/0092-8674(95)90172-8  0.354
1995 Ip NY, Yancopoulos GD. Neurotrophic factors and their receptors Progress in Brain Research. 105: 189-195. PMID 7568877 DOI: 10.1002/Ana.410350706  0.365
1994 Thaler CD, Suhr L, Ip N, Katz DM. Leukemia inhibitory factor and neurotrophins support overlapping populations of rat nodose sensory neurons in culture. Developmental Biology. 161: 338-44. PMID 8313987 DOI: 10.1006/Dbio.1994.1035  0.408
1994 Hyman C, Juhasz M, Jackson C, Wright P, Ip NY, Lindsay RM. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 335-47. PMID 8283241 DOI: 10.1523/Jneurosci.14-01-00335.1994  0.378
1994 Stahl N, Boulton TG, Farruggella T, Ip NY, Davis S, Witthuhn BA, Quelle FW, Silvennoinen O, Barbieri G, Pellegrini S, Ihle JN, Yancopoulos GD. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 β receptor components Science. 263: 92-95. PMID 8272873 DOI: 10.1126/Science.8272873  0.324
1994 Verdi JM, Ip N, Yancopoulos GD, Anderson DJ. Expression of trk in MAH cells lacking the p75 low-affinity nerve growth factor receptor is sufficient to permit nerve growth factor-induced differentiation to postmitotic neurons. Proceedings of the National Academy of Sciences of the United States of America. 91: 3949-53. PMID 8171018 DOI: 10.1073/Pnas.91.9.3949  0.385
1994 Chevalier S, Praloran V, Smith C, Grogan DM, Ip NY, Yancopoulos GD, Brachet P, Pouplard A, Gascan H. Expression and functionality of the trkA proto-oncogene product/NGF receptor in undifferentiated hematopoietic cells Blood. 83: 1479-1485. PMID 8123839 DOI: 10.1182/Blood.V83.6.1479.Bloodjournal8361479  0.317
1994 Rudge JS, Li Y, Pasnikowski EM, Mattsson K, Pan L, Yancopoulos GD, Wiegand SJ, Lindsay RM, Ip NY. Neurotrophic factor receptors and their signal transduction capabilities in rat astrocytes. The European Journal of Neuroscience. 6: 693-705. PMID 8075814 DOI: 10.1111/J.1460-9568.1994.Tb00981.X  0.355
1994 Ip NY, Boulton TG, Li Y, Verdi JM, Birren SJ, Anderson DJ, Yancopoulos GD. CNTF, FGF, and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons. Neuron. 13: 443-55. PMID 8060620 DOI: 10.1016/0896-6273(94)90359-X  0.396
1994 Ip NY, Yancopoulos GD. Neurotrophic factor receptors: just like other growth factor and cytokine receptors? Current Opinion in Neurobiology. 4: 400-405. PMID 7919935 DOI: 10.1016/0959-4388(94)90102-3  0.301
1994 Curtis R, Scherer SS, Somogyi R, Adryan KM, Ip NY, Zhu Y, Lindsay RM, DiStefano PS. Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve. Neuron. 12: 191-204. PMID 7507340 DOI: 10.1016/0896-6273(94)90163-5  0.348
1993 Lohof AM, Ip NY, Poo MM. Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature. 363: 350-3. PMID 8497318 DOI: 10.1038/363350A0  0.397
1993 Valenzuela DM, Maisonpierre PC, Glass DJ, Rojas E, Nuñez L, Kong Y, Gies DR, Stitt TN, Ip NY, Yancopoulos GD. Alternative forms of rat TrkC with different functional capabilities. Neuron. 10: 963-74. PMID 8494647 DOI: 10.1016/0896-6273(93)90211-9  0.371
1993 Davis S, Aldrich TH, Stahl N, Pan L, Taga T, Kishimoto T, Ip NY, Yancopoulos GD. LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science (New York, N.Y.). 260: 1805-8. PMID 8390097 DOI: 10.1126/Science.8390097  0.304
1993 Ip NY, McClain J, Barrezueta NX, Aldrich TH, Pan L, Li Y, Wiegand SJ, Friedman B, Davis S, Yancopoulos GD. The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Neuron. 10: 89-102. PMID 8381290 DOI: 10.1016/0896-6273(93)90245-M  0.318
1993 Ip NY, Wiegand SJ, Morse J, Rudge JS. Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brain. The European Journal of Neuroscience. 5: 25-33. PMID 8261087 DOI: 10.1111/J.1460-9568.1993.Tb00201.X  0.34
1993 Sofroniew MV, Cooper JD, Svendsen CN, Crossman P, Ip NY, Lindsay RM, Zafra F, Lindholm D. Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 5263-76. PMID 8254373 DOI: 10.1523/Jneurosci.13-12-05263.1993  0.406
1993 Ip NY, Li Y, Yancopoulos GD, Lindsay RM. Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 3394-405. PMID 7688038 DOI: 10.1523/Jneurosci.13-08-03394.1993  0.425
1993 Ip NY, Stitt TN, Tapley P, Klein R, Glass DJ, Fandl J, Greene LA, Barbacid M, Yancopoulos GD. Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells. Neuron. 10: 137-49. PMID 7679912 DOI: 10.1016/0896-6273(93)90306-C  0.413
1993 Wong V, Arriaga R, Ip NY, Lindsay RM. The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motor neurons. The European Journal of Neuroscience. 5: 466-74. PMID 7505167 DOI: 10.1111/J.1460-9568.1993.Tb00513.X  0.408
1993 Ip NY, Yancopoulos GD. Ciliary neurotrophic factor and its receptor complex. Progress in Growth Factor Research. 4: 139-55. PMID 1338574 DOI: 10.1016/0955-2235(92)90028-G  0.35
1993 Ip NY, Yancopoulos GD. Receptors and signaling pathways of ciliary neurotrophic factor and the neurotrophins Seminars in Neuroscience. 5: 249-257. DOI: 10.1016/S1044-5765(05)80030-2  0.334
1992 Rudge JS, Alderson RF, Pasnikowski E, McClain J, Ip NY, Lindsay RM. Expression of Ciliary Neurotrophic Factor and the Neurotrophins-Nerve Growth Factor, Brain-Derived Neurotrophic Factor and Neurotrophin 3-in Cultured Rat Hippocampal Astrocytes. The European Journal of Neuroscience. 4: 459-471. PMID 12106332 DOI: 10.1111/J.1460-9568.1992.Tb00896.X  0.362
1992 Ip NY, Nye SH, Boulton TG, Davis S, Taga T, Li Y, Birren SJ, Yasukawa K, Kishimoto T, Anderson DJ. CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130. Cell. 69: 1121-32. PMID 1617725 DOI: 10.1016/0092-8674(92)90634-O  0.376
1992 Nye SH, Squinto SP, Glass DJ, Stitt TN, Hantzopoulos P, Macchi MJ, Lindsay NS, Ip NY, Yancopoulos GD. K-252a and staurosporine selectively block autophosphorylation of neurotrophin receptors and neurotrophin-mediated responses. Molecular Biology of the Cell. 3: 677-86. PMID 1323351 DOI: 10.1091/Mbc.3.6.677  0.409
1991 Lindsay RM, Alderson RF, Friedman B, Hyman C, Ip NY, Furth ME, Maisonpierre PC, Squinto SP, Yancopoulos GD. The neurotrophin family of NGF-related neurotrophic factors. Restorative Neurology and Neuroscience. 2: 211-20. PMID 21551605 DOI: 10.3233/Rnn-1991-245608  0.422
1991 Boulton TG, Nye SH, Robbins DJ, Ip NY, Radziejewska E, Morgenbesser SD, DePinho RA, Panayotatos N, Cobb MH, Yancopoulos GD. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell. 65: 663-75. PMID 2032290 DOI: 10.1016/0092-8674(91)90098-J  0.358
1991 Ip NY, Li YP, van de Stadt I, Panayotatos N, Alderson RF, Lindsay RM. Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3124-34. PMID 1941077 DOI: 10.1523/Jneurosci.11-10-03124.1991  0.4
1991 Maisonpierre PC, Le Beau MM, Espinosa R, Ip NY, Belluscio L, de la Monte SM, Squinto S, Furth ME, Yancopoulos GD. Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations. Genomics. 10: 558-68. PMID 1889806 DOI: 10.1016/0888-7543(91)90436-I  0.318
1990 Maisonpierre PC, Belluscio L, Squinto S, Ip NY, Furth ME, Lindsay RM, Yancopoulos GD. Neurotrophin-3: a neurotrophic factor related to NGF and BDNF. Science (New York, N.Y.). 247: 1446-51. PMID 2321006 DOI: 10.1126/Science.2321006  0.322
1990 Yancopoulos GD, Maisonpierre PC, Ip NY, Aldrich TH, Belluscio L, Boulton TG, Cobb MH, Squinto SP, Furth ME. Neurotrophic factors, their receptors, and the signal transduction pathways they activate. Cold Spring Harbor Symposia On Quantitative Biology. 55: 371-9. PMID 1966766 DOI: 10.1101/Sqb.1990.055.01.038  0.349
1989 Schwarzschild MA, Vale W, Corigliano-Murphy AC, Pisano JJ, Ip NY, Zigmond RE. Activation of ganglionic tyrosine hydroxylase by peptides of the secretin-glucagon family: structure-function studies. Neuroscience. 31: 159-67. PMID 2570376 DOI: 10.1016/0306-4522(89)90037-7  0.566
1985 Ip NY, Zigmond RE. Long-term regulation of tyrosine hydroxylase activity in the superior cervical ganglion in organ culture: effects of nerve stimulation and dexamethasone. Brain Research. 338: 61-70. PMID 2862951 DOI: 10.1016/0006-8993(85)90248-3  0.562
1985 Ip NY, Baldwin C, Zigmond RE. Regulation of the concentration of adenosine 3',5'-cyclic monophosphate and the activity of tyrosine hydroxylase in the rat superior cervical ganglion by three neuropeptides of the secretin family. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 1947-54. PMID 2862228 DOI: 10.1523/Jneurosci.05-07-01947.1985  0.578
1985 Ip N, Baldwin C, Zigmond R. Regulation of the concentration of adenosine 3',5'-cyclic monophosphate and the activity of tyrosine hydroxylase in the rat superior cervical ganglion by three neuropeptides of the secretin family The Journal of Neuroscience. 5: 1947-1954. DOI: 10.1523/jneurosci.05-07-01947.1985  0.526
1984 Ip NY, Zigmond RE. Substance P inhibits the acute stimulation of ganglionic tyrosine hydroxylase activity by a nicotinic agonist. Neuroscience. 13: 217-20. PMID 6208508 DOI: 10.1016/0306-4522(84)90271-9  0.568
1984 Ip NY, Zigmond RE. Pattern of presynaptic nerve activity can determine the type of neurotransmitter regulating a postsynaptic event. Nature. 311: 472-4. PMID 6148705 DOI: 10.1038/311472A0  0.596
1984 Ip NY, Baldwin C, Zigmond RE. Acute stimulation of ganglionic tyrosine hydroxylase activity by secretin, VIP and PHI. Peptides. 5: 309-12. PMID 6147816 DOI: 10.1016/0196-9781(84)90225-0  0.562
1983 Ip NY, Perlman RL, Zigmond RE. Acute transsynaptic regulation of tyrosine 3-monooxygenase activity in the rat superior cervical ganglion: evidence for both cholinergic and noncholinergic mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 80: 2081-5. PMID 6132384 DOI: 10.1073/Pnas.80.7.2081  0.573
1982 Ip NY, Ho CK, Zigmond RE. Secretin and vasoactive intestinal peptide acutely increase tyrosine 3-monooxygenase in the rat superior cervical ganglion. Proceedings of the National Academy of Sciences of the United States of America. 79: 7566-9. PMID 6130526 DOI: 10.1073/Pnas.79.23.7566  0.579
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