Laura Segatori, Ph.D. - Publications

Chemical and Biomolecular Engineering Rice University, Houston, TX 
Protein folding and misfolding

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 di Ronza A, Bajaj L, Sharma J, Sanagasetti D, Lotfi P, Adamski CJ, Collette J, Palmieri M, Amawi A, Popp L, Chang KT, Meschini MC, Leung HE, Segatori L, Simonati A, et al. CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis. Nature Cell Biology. PMID 30397314 DOI: 10.1038/s41556-018-0228-7  0.32
2015 Song W, Popp L, Yang J, Kumar A, Gangoli VS, Segatori L. The autophagic response to polystyrene nanoparticles is mediated by transcription factor EB and depends on surface charge. Journal of Nanobiotechnology. 13: 87. PMID 26596266 DOI: 10.1186/s12951-015-0149-6  0.96
2015 Popp L, Segatori L. Differential autophagic responses to nano-sized materials. Current Opinion in Biotechnology. 36: 129-136. PMID 26340102 DOI: 10.1016/j.copbio.2015.08.016  0.96
2015 Kilpatrick K, Zeng Y, Hancock T, Segatori L. Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein. Plos One. 10: e0120819. PMID 25790376 DOI: 10.1371/journal.pone.0120819  0.96
2014 Song W, Soo Lee S, Savini M, Popp L, Colvin VL, Segatori L. Ceria nanoparticles stabilized by organic surface coatings activate the lysosome-autophagy system and enhance autophagic clearance. Acs Nano. 8: 10328-42. PMID 25315655 DOI: 10.1021/nn505073u  0.96
2014 Segatori L. Impairment of homeostasis in lysosomal storage disorders. Iubmb Life. 66: 472-7. PMID 25044960 DOI: 10.1002/iub.1288  0.96
2014 Wang J, Segatori L, Biswal SL. Probing the association of triblock copolymers with supported lipid membranes using microcantilevers. Soft Matter. 10: 6417-24. PMID 24978842 DOI: 10.1039/c4sm00928b  0.96
2014 Song W, Wang F, Lotfi P, Sardiello M, Segatori L. 2-Hydroxypropyl-β-cyclodextrin promotes transcription factor EB-mediated activation of autophagy: implications for therapy. The Journal of Biological Chemistry. 289: 10211-22. PMID 24558044 DOI: 10.1074/jbc.M113.506246  0.96
2014 Wang J, Morton MJ, Elliott CT, Karoonuthaisiri N, Segatori L, Biswal SL. Rapid detection of pathogenic bacteria and screening of phage-derived peptides using microcantilevers. Analytical Chemistry. 86: 1671-8. PMID 24417655 DOI: 10.1021/ac403437x  0.96
2014 Wang J, Liu KW, Segatori L, Biswal SL. Lipid bilayer phase transformations detected using microcantilevers. The Journal of Physical Chemistry. B. 118: 171-8. PMID 24345294 DOI: 10.1021/jp4095112  0.96
2013 Lee SS, Song W, Cho M, Puppala HL, Nguyen P, Zhu H, Segatori L, Colvin VL. Antioxidant properties of cerium oxide nanocrystals as a function of nanocrystal diameter and surface coating. Acs Nano. 7: 9693-703. PMID 24079896 DOI: 10.1021/nn4026806  0.96
2013 Mauri V, Lotfi P, Segatori L, Sardiello M. A rapid and sensitive method for measuring N-acetylglucosaminidase activity in cultured cells. Plos One. 8: e68060. PMID 23840811 DOI: 10.1371/journal.pone.0068060  0.96
2013 Wang F, Segatori L. Remodeling the proteostasis network to rescue glucocerebrosidase variants by inhibiting ER-associated degradation and enhancing ER folding. Plos One. 8: e61418. PMID 23620750 DOI: 10.1371/journal.pone.0061418  0.96
2013 Kilpatrick K, Novoa JA, Hancock T, Guerriero CJ, Wipf P, Brodsky JL, Segatori L. Chemical induction of Hsp70 reduces α-synuclein aggregation in neuroglioma cells. Acs Chemical Biology. 8: 1460-8. PMID 23594135 DOI: 10.1021/cb400017h  0.96
2013 Song W, Wang F, Savini M, Ake A, di Ronza A, Sardiello M, Segatori L. TFEB regulates lysosomal proteostasis. Human Molecular Genetics. 22: 1994-2009. PMID 23393155 DOI: 10.1093/hmg/ddt052  0.96
2012 Kothawala A, Kilpatrick K, Novoa JA, Segatori L. Quantitative analysis of α-synuclein solubility in living cells using split GFP complementation. Plos One. 7: e43505. PMID 22927976 DOI: 10.1371/journal.pone.0043505  0.96
2012 Mathieu JM, Wang F, Segatori L, Alvarez PJ. Increased resistance to oxysterol cytotoxicity in fibroblasts transfected with a lysosomally targeted Chromobacterium oxidase. Biotechnology and Bioengineering. 109: 2409-15. PMID 22447444 DOI: 10.1002/bit.24506  0.96
2011 Wang F, Song W, Brancati G, Segatori L. Inhibition of endoplasmic reticulum-associated degradation rescues native folding in loss of function protein misfolding diseases. The Journal of Biological Chemistry. 286: 43454-64. PMID 22006919 DOI: 10.1074/jbc.M111.274332  0.96
2011 Wang F, Chou A, Segatori L. Lacidipine remodels protein folding and Ca 2+ homeostasis in Gaucher's disease fibroblasts: a mechanism to rescue mutant glucocerebrosidase. Chemistry & Biology. 18: 766-76. PMID 21700212 DOI: 10.1016/j.chembiol.2011.04.008  0.96
2011 Wang F, Agnello G, Sotolongo N, Segatori L. Ca2+ homeostasis modulation enhances the amenability of L444P glucosylcerebrosidase to proteostasis regulation in patient-derived fibroblasts. Acs Chemical Biology. 6: 158-68. PMID 21043486 DOI: 10.1021/cb100321m  0.96
2008 Arredondo S, Segatori L, Gilbert HF, Georgiou G. De novo design and evolution of artificial disulfide isomerase enzymes analogous to the bacterial DsbC. The Journal of Biological Chemistry. 283: 31469-76. PMID 18782764 DOI: 10.1074/jbc.M803346200  0.96
2008 Mu TW, Ong DS, Wang YJ, Balch WE, Yates JR, Segatori L, Kelly JW. Chemical and biological approaches synergize to ameliorate protein-folding diseases. Cell. 134: 769-81. PMID 18775310 DOI: 10.1016/j.cell.2008.06.037  0.96
2006 Segatori L, Murphy L, Arredondo S, Kadokura H, Gilbert H, Beckwith J, Georgiou G. Conserved role of the linker alpha-helix of the bacterial disulfide isomerase DsbC in the avoidance of misoxidation by DsbB. The Journal of Biological Chemistry. 281: 4911-9. PMID 16280324 DOI: 10.1074/jbc.M505453200  0.96
2005 Georgiou G, Segatori L. Preparative expression of secreted proteins in bacteria: status report and future prospects. Current Opinion in Biotechnology. 16: 538-45. PMID 16095898 DOI: 10.1016/j.copbio.2005.07.008  0.96
2005 Segatori L, Arredondo S, Georgiau G. De novo engineering of a bacterial disulfide isomerase Aiche Annual Meeting, Conference Proceedings. 8058.  0.96
2004 Zhang M, Monzingo AF, Segatori L, Georgiou G, Robertus JD. Structure of DsbC from Haemophilus influenzae. Acta Crystallographica. Section D, Biological Crystallography. 60: 1512-8. PMID 15333920 DOI: 10.1107/S0907444904014593  0.96
2004 Segatori L, Paukstelis PJ, Gilbert HF, Georgiou G. Engineered DsbC chimeras catalyze both protein oxidation and disulfide-bond isomerization in Escherichia coli: Reconciling two competing pathways. Proceedings of the National Academy of Sciences of the United States of America. 101: 10018-23. PMID 15220477 DOI: 10.1073/pnas.0403003101  0.96
2004 Segatori L, Arredondo S, Georgiou G. Structure-function and de novo design of protein disulfide isomerases Aiche Annual Meeting, Conference Proceedings. 8749.  0.96
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