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Mark Joseph Kurth - Publications

Chemistry University of California, Davis, Davis, CA 
Combinatorial chemistry, heterocyclic chemistry, understanding reaction mechanisms, solid phase organic synthesis, polymer chemistry, organic synthesis, reaction methodology, and structure elucidation

213 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Phuan PW, Son JH, Tan JA, Li C, Musante I, Zlock L, Nielson DW, Finkbeiner WE, Kurth MJ, Galietta LJ, Haggie PM, Verkman AS. Combination potentiator ('co-potentiator') therapy for CF caused by CFTR mutants, including N1303K, that are poorly responsive to single potentiators. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 29903467 DOI: 10.1016/J.Jcf.2018.05.010  0.72
2016 Bagdasarian AL, Nguyen HH, Palazzo TA, Fettinger JC, Haddadin MJ, Kurth MJ. One-Pot Synthesis of Benzo[4,5]imidazo[2,1-a]isoquinolines and Isoquinolino[3,4-b]quinoxalines via Tandem Cyclization Strategies. The Journal of Organic Chemistry. PMID 27030441 DOI: 10.1021/Acs.Joc.6B00338  1
2015 Palazzo TA, Patra D, Yang JS, El Khoury E, Appleton MG, Haddadin MJ, Tantillo DJ, Kurth MJ. Dibenzonaphthyridinones: Heterocycle-to-Heterocycle Synthetic Strategies and Photophysical Studies. Organic Letters. PMID 26574652 DOI: 10.1021/Acs.Orglett.5B02680  1
2015 Nguyen HH, Fettinger JC, Haddadin MJ, Kurth MJ. Expedient one-pot synthesis of indolo[3,2-c]isoquinolines via a base-promoted N-alkylation/tandem cyclization. Tetrahedron Letters. 56: 5429-5433. PMID 26366017 DOI: 10.1016/J.Tetlet.2015.08.006  1
2015 Fujita M, Zhu K, Fujita CK, Zhao M, Lam KS, Kurth MJ, Takada YK, Takada Y. Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1. The Journal of Biological Chemistry. 290: 259-71. PMID 25398877 DOI: 10.1074/Jbc.M114.579946  1
2015 Palazzo TA, Truong TT, Wong SMT, Mack ET, Lodewyk MW, Harrison JG, Gamage RA, Siegel JB, Kurth MJ, Tantillo DJ. Reassigning the structures of natural products using NMR chemical shifts computed with quantum mechanics: A laboratory exercise Journal of Chemical Education. 92: 561-566. DOI: 10.1021/Ed4006584  1
2015 Wedler HB, Palazzo TA, Pemberton RP, Hamann CS, Kurth MJ, Tantillo DJ. Predicting hydration propensities of biologically relevant α-ketoamides Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.08.010  1
2014 Ye L, Hu B, El-Badri F, Hudson BM, Phuan PW, Verkman AS, Tantillo DJ, Kurth MJ. ΔF508-CFTR correctors: synthesis and evaluation of thiazole-tethered imidazolones, oxazoles, oxadiazoles, and thiadiazoles. Bioorganic & Medicinal Chemistry Letters. 24: 5840-4. PMID 25452003 DOI: 10.1016/J.Bmcl.2014.09.067  1
2014 Roth A, Ott S, Farber KM, Palazzo TA, Conrad WE, Haddadin MJ, Tantillo DJ, Cross CE, Eiserich JP, Kurth MJ. Inhibition of myeloperoxidase: evaluation of 2H-indazoles and 1H-indazolones. Bioorganic & Medicinal Chemistry. 22: 6422-9. PMID 25438766 DOI: 10.1016/J.Bmc.2014.09.044  1
2014 Coffman KC, Nguyen HH, Phuan PW, Hudson BM, Yu GJ, Bagdasarian AL, Montgomery D, Lodewyk MW, Yang B, Yoo CL, Verkman AS, Tantillo DJ, Kurth MJ. Constrained bithiazoles: small molecule correctors of defective ΔF508-CFTR protein trafficking. Journal of Medicinal Chemistry. 57: 6729-38. PMID 25061695 DOI: 10.1021/Jm5007885  1
2014 Farber KM, Haddadin MJ, Kurth MJ. Davis-Beirut reaction: route to thiazolo-, thiazino-, and thiazepino-2H-indazoles. The Journal of Organic Chemistry. 79: 6939-45. PMID 25019525 DOI: 10.1021/Jo501014E  1
2014 Kurth MJ, Yokoi T, Gershwin ME. Halothane-induced hepatitis: paradigm or paradox for drug-induced liver injury. Hepatology (Baltimore, Md.). 60: 1473-5. PMID 24913773 DOI: 10.1002/Hep.27253  1
2014 Patra D, Palazzo TA, Malaeb NN, Haddadin MJ, Tantillo DJ, Kurth MJ. Cyclic azacyanines: experimental and computational studies on spectroscopic properties and unique reactivity. Journal of Fluorescence. 24: 1285-96. PMID 24910112 DOI: 10.1007/S10895-014-1413-0  1
2014 Kurth LL, Kurth MJ. Synthesis-spectroscopy roadmap problems: Discovering organic chemistry Journal of Chemical Education. 91: 2137-2141. DOI: 10.1021/Ed500109A  1
2014 Coffman KC, Duong V, Bagdasarian AL, Fettinger JC, Haddadin MJ, Kurth MJ. Heterocycle-to-heterocycle route to quinoline-4-amines: Reductive heterocyclization of 3-(2-nitrophenyl)isoxazoles European Journal of Organic Chemistry. 2014: 7651-7657. DOI: 10.1002/ejoc.201403065  1
2013 Nguyen HH, Palazzo TA, Kurth MJ. Facile one-pot assembly of imidazotriazolobenzodiazepines via indium(III)-catalyzed multicomponent reactions. Organic Letters. 15: 4492-5. PMID 23961714 DOI: 10.1021/Ol402045H  1
2013 Wang J, Budamagunta MS, Voss JC, Kurth MJ, Lam KS, Lu L, Kenny TP, Bowlus C, Kikuchi K, Coppel RL, Ansari AA, Gershwin ME, Leung PS. Antimitochondrial antibody recognition and structural integrity of the inner lipoyl domain of the E2 subunit of pyruvate dehydrogenase complex. Journal of Immunology (Baltimore, Md. : 1950). 191: 2126-33. PMID 23894195 DOI: 10.4049/Jimmunol.1301092  1
2013 Snyder DS, Tradtrantip L, Battula S, Yao C, Phuan PW, Fettinger JC, Kurth MJ, Verkman AS. ABSOLUTE CONFIGURATION AND BIOLOGICAL PROPERTIES OF ENANTIOMERS OF CFTR INHIBITOR BPO-27. Acs Medicinal Chemistry Letters. 4: 456-459. PMID 23814642 DOI: 10.1021/Ml400069K  1
2013 Okiyoneda T, Veit G, Dekkers JF, Bagdany M, Soya N, Xu H, Roldan A, Verkman AS, Kurth M, Simon A, Hegedus T, Beekman JM, Lukacs GL. Mechanism-based corrector combination restores ΔF508-CFTR folding and function. Nature Chemical Biology. 9: 444-54. PMID 23666117 DOI: 10.1038/Nchembio.1253  1
2013 Coffman KC, Palazzo TA, Hartley TP, Fettinger JC, Tantillo DJ, Kurth MJ. Heterocycle-heterocycle strategies: (2-nitrophenyl)isoxazole precursors to 4-aminoquinolines, 1H-indoles, and quinolin-4(1H)-ones. Organic Letters. 15: 2062-5. PMID 23557405 DOI: 10.1021/Ol400787Y  1
2013 Leung PS, Wang J, Naiyanetr P, Kenny TP, Lam KS, Kurth MJ, Gershwin ME. Environment and primary biliary cirrhosis: electrophilic drugs and the induction of AMA. Journal of Autoimmunity. 41: 79-86. PMID 23352659 DOI: 10.1016/J.Jaut.2012.12.007  1
2013 Nguyen HH, Kurth MJ. Microwave-assisted synthesis of 3-nitroindoles from N-aryl enamines via intramolecular arene-alkene coupling. Organic Letters. 15: 362-5. PMID 23268775 DOI: 10.1021/Ol303314X  1
2013 Chen RC, Naiyanetr P, Shu SA, Wang J, Yang GX, Kenny TP, Guggenheim KC, Butler JD, Bowlus C, Tao MH, Kurth MJ, Ansari AA, Kaplan M, Coppel RL, Lleo A, et al. Antimitochondrial antibody heterogeneity and the xenobiotic etiology of primary biliary cirrhosis. Hepatology (Baltimore, Md.). 57: 1498-508. PMID 23184636 DOI: 10.1002/Hep.26157  1
2013 Ye L, Dickerson T, Kaur H, Takada YK, Fujita M, Liu R, Knapp JM, Lam KS, Schore NE, Kurth MJ, Takada Y. Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3. Bioorganic & Medicinal Chemistry Letters. 23: 340-5. PMID 23164706 DOI: 10.1016/J.Bmcl.2012.10.080  1
2012 Avila B, El-Dakdouki MH, Nazer MZ, Harrison JG, Tantillo DJ, Haddadin MJ, Kurth MJ. Acid and base catalyzed Davis-Beirut reaction: experimental and theoretical mechanistic studies and synthesis of novel 3-amino-2H-indazoles. Tetrahedron Letters. 53: 6475-6478. PMID 23139435 DOI: 10.1016/J.Tetlet.2012.09.026  1
2012 Haddadin MJ, Conrad WE, Kurth MJ. The Davis-Beirut Reaction: a novel entry into 2H-indazoles and indazolones. Recent biological activity of indazoles. Mini Reviews in Medicinal Chemistry. 12: 1293-300. PMID 23092440 DOI: 10.2174/138955712802762059  1
2012 Knapp JM, Zhu JS, Tantillo DJ, Kurth MJ. Multicomponent assembly of highly substituted indoles by dual palladium-catalyzed coupling reactions. Angewandte Chemie (International Ed. in English). 51: 10588-91. PMID 23001913 DOI: 10.1002/Anie.201204633  1
2012 Leung PS, Lam K, Kurth MJ, Coppel RL, Gershwin ME. Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis? Trends in Molecular Medicine. 18: 577-82. PMID 22920894 DOI: 10.1016/J.Molmed.2012.07.005  1
2012 Avila B, Roth A, Streets H, Dwyer DS, Kurth MJ. Triazolbenzo[d]thiazoles: efficient synthesis and biological evaluation as neuroprotective agents. Bioorganic & Medicinal Chemistry Letters. 22: 5976-8. PMID 22892117 DOI: 10.1016/J.Bmcl.2012.07.022  1
2012 Donald MB, Rodriguez KX, Shay H, Phuan PW, Verkman AS, Kurth MJ. Click-based synthesis of triazolobithiazole ΔF508-CFTR correctors for cystic fibrosis. Bioorganic & Medicinal Chemistry. 20: 5247-53. PMID 22841006 DOI: 10.1016/j.bmc.2012.06.046  1
2012 Conrad WE, Rodriguez KX, Nguyen HH, Fettinger JC, Haddadin MJ, Kurth MJ. A one-pot-three-step route to triazolotriazepinoindazolones from oxazolino-2H-indazoles. Organic Letters. 14: 3870-3. PMID 22823414 DOI: 10.1021/Ol3015804  1
2012 Shoker TA, Ghattass KI, Fettinger JC, Kurth MJ, Haddadin MJ. Unusual Friedlander reactions: a route to novel quinoxaline-based heterocycles. Organic Letters. 14: 3704-7. PMID 22783916 DOI: 10.1021/Ol301550E  1
2012 Ibarra-Soza JM, Morris AA, Jayalath P, Peacock H, Conrad WE, Donald MB, Kurth MJ, Beal PA. 7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove. Organic & Biomolecular Chemistry. 10: 6491-7. PMID 22766576 DOI: 10.1039/C2Ob25647A  1
2012 Guggenheim KG, Toru H, Kurth MJ. One-pot, two-step cascade synthesis of quinazolinotriazolobenzodiazepines. Organic Letters. 14: 3732-5. PMID 22746550 DOI: 10.1021/Ol301592Z  1
2012 Coffman KC, Hartley TP, Dallas JL, Kurth MJ. Isoxazolodihydropyridinones: 1,3-dipolar cycloaddition of nitrile oxides onto 2,4-dioxopiperidines. Acs Combinatorial Science. 14: 280-4. PMID 22352295 DOI: 10.1021/Co200200U  1
2012 Davison HR, Solano DM, Phuan PW, Verkman AS, Kurth MJ. Fluorinated ΔF508-CFTR correctors and potentiators for PET imaging. Bioorganic & Medicinal Chemistry Letters. 22: 1602-5. PMID 22281185 DOI: 10.1016/J.Bmcl.2011.12.128  1
2012 Knapp JM, Wood AB, Phuan PW, Lodewyk MW, Tantillo DJ, Verkman AS, Kurth MJ. Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in ΔF508 cystic fibrosis transmembrane conductance regulator protein. Journal of Medicinal Chemistry. 55: 1242-51. PMID 22214395 DOI: 10.1021/Jm201372Q  1
2012 Knapp JM, Zhu JS, Wood AB, Kurth MJ. Expedient synthesis of a 72-membered isoxazolino-β-ketoamide library by a 2·3-component reaction. Acs Combinatorial Science. 14: 85-8. PMID 22181856 DOI: 10.1021/Co200199H  1
2012 Patra D, Malaeb NN, Haddadin MJ, Kurth MJ. Influence of substituent and solvent on the radiative process of singlet excited states of novel cyclic azacyanine derivatives. Journal of Fluorescence. 22: 707-17. PMID 22045406 DOI: 10.1007/S10895-011-1006-0  1
2011 Davison HR, Taylor S, Drake C, Phuan PW, Derichs N, Yao C, Jones EF, Sutcliffe J, Verkman AS, Kurth MJ. Functional fluorescently labeled bithiazole ΔF508-CFTR corrector imaged in whole body slices in mice. Bioconjugate Chemistry. 22: 2593-9. PMID 22034937 DOI: 10.1021/Bc2004457  1
2011 Haddadin MJ, El-Khatib M, Shoker TA, Beavers CM, Olmstead MM, Fettinger JC, Farber KM, Kurth MJ. Quinoxalino[2,3-c]cinnolines and their 5-N-oxide: alkoxylation of methyl-substituted quinoxalino[2,3-c]cinnolines to acetals and orthoesters. The Journal of Organic Chemistry. 76: 8421-7. PMID 21905671 DOI: 10.1021/Jo201687X  1
2011 Knapp JM, Fettinger JC, Kurth MJ. Multicomponent macrocyclization reactions (MCMRs) employing highly reactive acyl ketene and nitrile oxide intermediates. Organic Letters. 13: 4732-5. PMID 21827181 DOI: 10.1021/Ol202024A  1
2011 Naiyanetr P, Butler JD, Meng L, Pfeiff J, Kenny TP, Guggenheim KG, Reiger R, Lam K, Kurth MJ, Ansari AA, Coppel RL, López-Hoyos M, Gershwin ME, Leung PS. Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity. Journal of Autoimmunity. 37: 209-16. PMID 21763105 DOI: 10.1016/J.Jaut.2011.06.001  1
2011 Meng L, Fettinger JC, Kurth MJ. Ethyl 1-benzyl-1,2,3,3a,4,10b-hexa-hydro-pyrrolo-[2',3':3,4]pyrrolo-[1,2-a]benzimidazole-2-carboxyl-ate. Acta Crystallographica. Section E, Structure Reports Online. 67: o1214. PMID 21754512 DOI: 10.1107/S1600536811014292  1
2011 Phuan PW, Yang B, Knapp JM, Wood AB, Lukacs GL, Kurth MJ, Verkman AS. Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis. Molecular Pharmacology. 80: 683-93. PMID 21730204 DOI: 10.1124/Mol.111.073056  1
2011 Snyder DS, Tradtrantip L, Yao C, Kurth MJ, Verkman AS. Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease. Journal of Medicinal Chemistry. 54: 5468-77. PMID 21707078 DOI: 10.1021/Jm200505E  1
2011 Guggenheim KG, Butler JD, Painter PP, Lorsbach BA, Tantillo DJ, Kurth MJ. Synthesis of spiro-fused pyrazolidoylisoxazolines. The Journal of Organic Chemistry. 76: 5803-12. PMID 21650164 DOI: 10.1021/Jo200924Y  1
2011 Conrad WE, Fukazawa R, Haddadin MJ, Kurth MJ. The Davis-Beirut reaction: N1,N2-disubstituted-1H-indazolones via 1,6-electrophilic addition to 3-alkoxy-2H-indazoles. Organic Letters. 13: 3138-41. PMID 21612219 DOI: 10.1021/Ol2010424  1
2011 Avila B, Solano DM, Haddadin MJ, Kurth MJ. Facile syntheses of novel benzo-1,3-dioxolo-, benzothiazolo-, pyrido-, and quinolino-fused 5H-benzo[d]-pyrazolo[5,1-b][1,3]-oxazines and 1H-pyrazoles. Organic Letters. 13: 1060-3. PMID 21294577 DOI: 10.1021/Ol103108Z  1
2011 Ferreira AJ, Solano DM, Oakdale JS, Kurth MJ. Novel trinitrogen-containing triheterocycles via the intramolecular nitrile oxide cycloaddition reaction Synthesis. 3241-3246. DOI: 10.1055/S-0030-1260188  1
2011 Solano DM, Wood FE, Kurth MJ. "Careers in chemistry": A course providing students with real-world foundations Journal of Chemical Education. 88: 1376-1379. DOI: 10.1021/Ed1001366  1
2010 Yu GJ, Yang B, Verkman AS, Kurth MJ. Isoxazolopyrimidines as Novel ΔF508-CFTR Correctors. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2010: 1063-1066. PMID 23710112 DOI: 10.1055/S-0029-1219781  1
2010 Haddadin MJ, Bou Zerdan RM, Kurth MJ, Fettinger JC. Efficient syntheses of the unknown quinolino[2,3-c]cinnolines; synthesis of neocryptolepines. Organic Letters. 12: 5502-5. PMID 21067220 DOI: 10.1021/Ol102376A  1
2010 Carpenter RD, Kurth MJ. A rapid and efficient route to benzazole heterocycles. Nature Protocols. 5: 1731-6. PMID 21030949 DOI: 10.1038/Nprot.2010.132  1
2010 Yao N, Fung G, Malekan H, Ye L, Kurth MJ, Lam KS. Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation. Carbohydrate Research. 345: 2277-81. PMID 20832778 DOI: 10.1016/J.Carres.2010.07.040  1
2010 Butler JD, Coffman KC, Ziebart KT, Toney MD, Kurth MJ. Orthogonally protected thiazole and isoxazole diamino acids: an efficient synthetic route. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 9002-5. PMID 20623732 DOI: 10.1002/Chem.201001492  1
2010 Butler JD, Conrad WE, Lodewyk MW, Fettinger JC, Tantillo DJ, Kurth MJ. Synthesis of substituted chromanones: an organocatalytic aldol/oxa-Michael reaction. Organic Letters. 12: 3410-3. PMID 20617821 DOI: 10.1021/Ol101221C  1
2010 Carpenter RD, Natarajan A, Lau EY, Andrei M, Solano DM, Lightstone FC, Denardo SJ, Lam KS, Kurth MJ. Halogenated benzimidazole carboxamides target integrin alpha4beta1 on T-cell and B-cell lymphomas. Cancer Research. 70: 5448-56. PMID 20530664 DOI: 10.1158/0008-5472.Can-09-3736  1
2010 Donald MB, Conrad WE, Oakdale JS, Butler JD, Haddadin MJ, Kurth MJ. Nucleophilic substitution of oxazino-/oxazolino-/benzoxazin [3,2-b]indazoles: an effective route to 1H-indazolones. Organic Letters. 12: 2524-7. PMID 20438102 DOI: 10.1021/Ol100751N  1
2010 Ye L, Knapp JM, Sangwung P, Fettinger JC, Verkman AS, Kurth MJ. Pyrazolylthiazole as DeltaF508-cystic fibrosis transmembrane conductance regulator correctors with improved hydrophilicity compared to bithiazoles. Journal of Medicinal Chemistry. 53: 3772-81. PMID 20373765 DOI: 10.1021/Jm100235H  1
2010 Ziebart KT, Dixon SM, Avila B, El-Badri MH, Guggenheim KG, Kurth MJ, Toney MD. Targeting multiple chorismate-utilizing enzymes with a single inhibitor: validation of a three-stage design. Journal of Medicinal Chemistry. 53: 3718-29. PMID 20359225 DOI: 10.1021/Jm100158V  1
2010 Meng L, Lorsbach BA, Sparks TC, Fettinger JC, Kurth MJ. Parallel Synthesis of bis-heterocyclic isoxazolylmethyl- and isoxazolinylmethylpyrazoles. Journal of Combinatorial Chemistry. 12: 129-36. PMID 20000375 DOI: 10.1021/Cc900133K  1
2010 Ye L, Haddadin MJ, Lodewyk MW, Ferreira AJ, Fettinger JC, Tantillo DJ, Kurth MJ. Cyclopenta[b]pyrroles from triazines: synthetic and mechanistic studies. Organic Letters. 12: 164-7. PMID 19961148 DOI: 10.1021/Ol902559U  1
2010 Mills AD, Yoo C, Butler JD, Yang B, Verkman AS, Kurth MJ. Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR. Bioorganic & Medicinal Chemistry Letters. 20: 87-91. PMID 19954980 DOI: 10.1016/J.Bmcl.2009.11.020  1
2010 Butler JD, Choung W, Kurth MJ. Flash chromatography: A novel pressurization apparatus Journal of Chemical Education. 87: 1265. DOI: 10.1021/Ed100416X  1
2010 Haddadin MJ, El-Nachef C, Kisserwani H, Chaaban Y, Kurth MJ, Fettinger JC. 2-Benzyliden-2H-thieto[3,2-b]quinoline: A new heterocycle and its rearrangement to 2-phenylthieno[3,2-b]quinoline Tetrahedron Letters. 51: 6687-6689. DOI: 10.1016/J.Tetlet.2010.10.039  1
2010 Solano DM, Butler JD, Haddadin MJ, Kurth MJ, Baucom KD, Faul MM. One-pot synthesis of 5H-indazolo-[3,2-b]benzo[d]-1,3-oxazine: Two efficient preparative methods Organic Syntheses. 87: 339-349. DOI: 10.1002/0471264229.Os087.36  1
2009 Meng L, Wang SC, Fettinger JC, Kurth MJ, Tantillo DJ. Controlling Selectivity for Cycloadditions of Nitrones and Alkenes Tethered by Benzimidazoles: Combining Experiment and Theory. European Journal of Organic Chemistry. 2009. PMID 24327801 DOI: 10.1002/Ejoc.200801211  1
2009 Milinkevich KA, Yoo CL, Sparks TC, Lorsbach BA, Kurth MJ. Synthesis and biological activity of 2-(4,5-dihydroisoxazol-5-yl)-1,3,4-oxadiazoles. Bioorganic & Medicinal Chemistry Letters. 19: 5796-8. PMID 19700317 DOI: 10.1016/J.Bmcl.2009.07.139  1
2009 Yu GJ, Iwamoto S, Robins LI, Fettinger JC, Sparks TC, Lorsbach BA, Kurth MJ. 3-(Arylthiomethyl)isoxazole-4,5-dicarboxamides: chemoselective nucleophilic chemistry and insecticidal activity. Journal of Agricultural and Food Chemistry. 57: 7422-6. PMID 19624156 DOI: 10.1021/Jf901512T  1
2009 Oakdale JS, Solano DM, Fettinger JC, Haddadin MJ, Kurth MJ. An oxazolo[3,2-b]indazole route to 1H-indazolones. Organic Letters. 11: 2760-3. PMID 19505119 DOI: 10.1021/Ol900891S  1
2009 Lodewyk MW, Kurth MJ, Tantillo DJ. Mechanisms for formation of diazocinones, pyridazines, and pyrazolines from tetrazines--oxyanion-accelerated pericyclic cascades? The Journal of Organic Chemistry. 74: 4804-11. PMID 19485385 DOI: 10.1021/Jo900565Y  1
2009 El-Badri MH, Kurth MJ. Synthesis of thiazolo- and 7,8-dihydrothiazolo[4,5-e]benzoisoxazoles. Journal of Combinatorial Chemistry. 11: 228-38. PMID 19154120 DOI: 10.1021/Cc800141S  1
2009 Carpenter RD, Andrei M, Aina OH, Lau EY, Lightstone FC, Liu R, Lam KS, Kurth MJ. Selectively targeting T- and B-cell lymphomas: a benzothiazole antagonist of alpha4beta1 integrin. Journal of Medicinal Chemistry. 52: 14-9. PMID 19072684 DOI: 10.1021/Jm800313F  1
2009 Milinkevich KA, Kurth MJ. Preparation of a spiroisoxazolinopiperidinylbenzamide-based scaffold Synlett. 3019-3023. DOI: 10.1055/S-0029-1218290  1
2009 Butler JD, Donald MB, Ding Z, Fettinger JC, Kurth MJ. Phenylsulfonyl as a directing group for nitrile oxide cycloadditions and mCPBA epoxidations Tetrahedron Letters. 50: 5110-5112. DOI: 10.1016/J.Tetlet.2009.06.100  1
2008 Schwarzer C, Fischer H, Kim EJ, Barber KJ, Mills AD, Kurth MJ, Gruenert DC, Suh JH, Machen TE, Illek B. Oxidative stress caused by pyocyanin impairs CFTR Cl(-) transport in human bronchial epithelial cells. Free Radical Biology & Medicine. 45: 1653-62. PMID 18845244 DOI: 10.1016/J.Freeradbiomed.2008.09.011  1
2008 Yu GJ, Yoo CL, Yang B, Lodewyk MW, Meng L, El-Idreesy TT, Fettinger JC, Tantillo DJ, Verkman AS, Kurth MJ. Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy. Journal of Medicinal Chemistry. 51: 6044-54. PMID 18788728 DOI: 10.1021/Jm800533C  1
2008 Carpenter RD, Fettinger JC, Lam KS, Kurth MJ. Asymmetric catalysis: resin-bound hydroxyprolylthreonine derivatives in enamine-mediated reactions. Angewandte Chemie (International Ed. in English). 47: 6407-10. PMID 18624312 DOI: 10.1002/Anie.200801811  1
2008 Al-Nakkash L, Springsteel MF, Kurth MJ, Nantz MH. Activation of CFTR by UCCF-029 and genistein. Bioorganic & Medicinal Chemistry Letters. 18: 3874-7. PMID 18595696 DOI: 10.1016/J.Bmcl.2008.06.051  1
2008 Wakabayashi K, Lian ZX, Leung PS, Moritoki Y, Tsuneyama K, Kurth MJ, Lam KS, Yoshida K, Yang GX, Hibi T, Ansari AA, Ridgway WM, Coppel RL, Mackay IR, Gershwin ME. Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease. Hepatology (Baltimore, Md.). 48: 531-40. PMID 18563844 DOI: 10.1002/Hep.22390  1
2008 Milinkevich KA, Ye L, Kurth MJ. Synthesis of 5-(thiazol-5-yl)-4,5-dihydroisoxazoles from 3-chloropentane-2,4-dione. Journal of Combinatorial Chemistry. 10: 521-5. PMID 18505299 DOI: 10.1021/Cc800033M  1
2008 Yoo CL, Yu GJ, Yang B, Robins LI, Verkman AS, Kurth MJ. 4'-Methyl-4,5'-bithiazole-based correctors of defective delta F508-CFTR cellular processing. Bioorganic & Medicinal Chemistry Letters. 18: 2610-4. PMID 18394886 DOI: 10.1016/J.Bmcl.2008.03.037  1
2008 Carpenter RD, DeBerdt PB, Holden JB, Milinkevich KA, Min T, Willenbring D, Fettinger JC, Tantillo DJ, Kurth MJ. Design and synthesis of propeller-shaped dispiroisoxazolinopiperidinochromanones. Journal of Combinatorial Chemistry. 10: 225-9. PMID 18232646 DOI: 10.1021/Cc700173X  1
2008 Butler JD, Solano DM, Robins LI, Haddadin MJ, Kurth MJ. A facile synthesis of new 5H-indazolo[3,2-b]benzo[d]-1,3-oxazines via one-pot intramolecular Bis-heterocyclizations. The Journal of Organic Chemistry. 73: 234-40. PMID 18052193 DOI: 10.1021/Jo702067Z  1
2008 Choung W, Lorsbach BA, Sparks TC, Ruiz JM, Kurth MJ. 4-(Isoxazol-3-yl)pyrimidines from pyrimidinyl nitrile oxides Synlett. 3036-3040. DOI: 10.1055/S-0028-1087346  1
2007 Meng L, Fettinger JC, Kurth MJ. Intramolecular cycloaddition of azomethine ylides in the preparation of pyrrolidino[2',3':3,4]pyrrolidino[1,2- a]benzimidazoles. Organic Letters. 9: 5055-8. PMID 17973485 DOI: 10.1021/Ol702301N  1
2007 Carpenter RD, Andrei M, Lau EY, Lightstone FC, Liu R, Lam KS, Kurth MJ. Highly potent, water soluble benzimidazole antagonist for activated alpha 4 beta 1 integrin. Journal of Medicinal Chemistry. 50: 5863-7. PMID 17948981 DOI: 10.1021/Jm070790O  1
2007 Jeddeloh MR, Holden JB, Nouri DH, Kurth MJ. A library of 3-aryl-4,5-dihydroisoxazole-5-carboxamides. Journal of Combinatorial Chemistry. 9: 1041-5. PMID 17910514 DOI: 10.1021/Cc700117A  1
2007 Leung PS, Park O, Tsuneyama K, Kurth MJ, Lam KS, Ansari AA, Coppel RL, Gershwin ME. Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization. Journal of Immunology (Baltimore, Md. : 1950). 179: 2651-7. PMID 17675529 DOI: 10.4049/Jimmunol.179.4.2651  1
2007 Robins LI, Kurth MJ. 1,3,5-triazine-based mass spectral tagging of one-bead one-compound libraries. Organic Letters. 9: 171-3. PMID 17217257 DOI: 10.1021/Ol062466D  1
2007 Mills AD, Maloney P, Hassanein E, Haddadin MJ, Kurth MJ. Synthesis of a library of 2-alkyl-3-alkyloxy-2H-indazole-6-carboxamides. Journal of Combinatorial Chemistry. 9: 171-7. PMID 17206845 DOI: 10.1021/Cc060109O  1
2007 Dixon SM, Milinkevich KA, Fujii J, Liu R, Yao N, Lam KS, Kurth MJ. A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead-one-compound library synthesis. Journal of Combinatorial Chemistry. 9: 143-57. PMID 17206843 DOI: 10.1021/Cc060090P  1
2007 Robins LI, Fettinger JC, Tinti DS, Kurth MJ. Selective nucleophilic chemistry in the synthesis of 5-carbamoyl-3-sulfanylmethylisoxazole-4-carboxylic acids. Journal of Combinatorial Chemistry. 9: 139-42. PMID 17206842 DOI: 10.1021/Cc0601074  1
2007 Carpenter RD, Lam KS, Kurth MJ. Microwave-mediated heterocyclization to benzimidazo[2,1-b]quinazolin-12(5H)-ones. The Journal of Organic Chemistry. 72: 284-7. PMID 17194113 DOI: 10.1021/Jo0618066  1
2007 Varela MC, Dixon SM, Price MD, Merit JE, Berget PE, Shiraki S, Kurth MJ, Schore NE. Comparison of enantioselective reductions using bead and monolith 'disk' polymer formulations of CBS catalysts Tetrahedron. 63: 3334-3339. DOI: 10.1016/J.Tet.2007.02.048  1
2006 Suen YF, Hope H, Nantz MH, Haddadin MJ, Kurth AM. Transannular Anti-Michael Addition: Formation of 4H-Pyrazolo[5,1-c]thiazines. Tetrahedron Letters. 47: 7893-7896. PMID 21904417 DOI: 10.1016/J.Tetlet.2006.09.015  1
2006 Dixon S, Ziebart KT, He Z, Jeddeloh M, Yoo CL, Wang X, Lehman A, Lam KS, Toney MD, Kurth MJ. Aminodeoxychorismate synthase inhibitors from one-bead one-compound combinatorial libraries: "staged" inhibitor design. Journal of Medicinal Chemistry. 49: 7413-26. PMID 17149871 DOI: 10.1021/Jm0609869  1
2006 Carpenter RD, Deberdt PB, Lam KS, Kurth MJ. Carbodiimide-based benzimidazole library method. Journal of Combinatorial Chemistry. 8: 907-14. PMID 17096580 DOI: 10.1021/Cc060106B  1
2006 Robins LI, Dixon SM, Wilson DK, Kurth MJ. On-bead combinatorial techniques for the identification of selective aldose reductase inhibitors. Bioorganic & Medicinal Chemistry. 14: 7728-35. PMID 16931029 DOI: 10.1016/J.Bmc.2006.08.005  1
2006 Rieger R, Leung PS, Jeddeloh MR, Kurth MJ, Nantz MH, Lam KS, Barsky D, Ansari AA, Coppel RL, Mackay IR, Gershwin ME. Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis. Journal of Autoimmunity. 27: 7-16. PMID 16876981 DOI: 10.1016/J.Jaut.2006.06.002  1
2006 Dixon SM, Li P, Liu R, Wolosker H, Lam KS, Kurth MJ, Toney MD. Slow-binding human serine racemase inhibitors from high-throughput screening of combinatorial libraries. Journal of Medicinal Chemistry. 49: 2388-97. PMID 16610782 DOI: 10.1021/Jm050701C  1
2006 Mills AD, Nazer MZ, Haddadin MJ, Kurth MJ. N,N-bond-forming heterocyclization: synthesis of 3-alkoxy-2H-indazoles. The Journal of Organic Chemistry. 71: 2687-9. PMID 16555821 DOI: 10.1021/Jo0524831  1
2006 Robins LI, Carpenter RD, Fettinger JC, Haddadin MJ, Tinti DS, Kurth MJ. Diazocinones: synthesis and conformational analysis. The Journal of Organic Chemistry. 71: 2480-5. PMID 16526800 DOI: 10.1021/Jo052577A  1
2006 Suen YF, Robins L, Yang B, Verkman AS, Nantz MH, Kurth MJ. Sulfamoyl-4-oxoquinoline-3-carboxamides: novel potentiators of defective DeltaF508-cystic fibrosis transmembrane conductance regulator chloride channel gating. Bioorganic & Medicinal Chemistry Letters. 16: 537-40. PMID 16288863 DOI: 10.1016/J.Bmcl.2005.10.050  1
2006 Liu Y, Mills AD, Kurth MJ. Solid phase synthesis of 3-(5-arylpyridin-2-yl)-4-hydroxycoumarins Tetrahedron Letters. 47: 1985-1988. DOI: 10.1016/J.Tetlet.2006.01.069  1
2006 Yoo CL, Olmstead MM, Tantillo DJ, Kurth MJ. Synthesis of 2H-pyrroles via the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides Tetrahedron Letters. 47: 477-481. DOI: 10.1016/J.Tetlet.2005.11.066  1
2005 Suen YF, Hope H, Nantz MH, Haddadin MJ, Kurth MJ. A novel route to fully substituted 1H-pyrazoles. The Journal of Organic Chemistry. 70: 8468-71. PMID 16209593 DOI: 10.1021/Jo051319A  1
2005 Yoo CL, Fettinger JC, Kurth MJ. Stannous chloride in alcohol: a one-pot conversion of 2-nitro-N-arylbenzamides to 2,3-dihydro-1H-quinazoline-4-ones. The Journal of Organic Chemistry. 70: 6941-3. PMID 16095321 DOI: 10.1021/Jo050450F  1
2005 Dixon S, Robins L, Elling RA, Liu R, Lam KS, Wilson DK, Kurth MJ. Discovery of selective aldo-keto reductase ligands--an on-bead assay strategy. Bioorganic & Medicinal Chemistry Letters. 15: 2938-42. PMID 15911284 DOI: 10.1016/J.Bmcl.2005.03.010  1
2005 Amano K, Leung PS, Rieger R, Quan C, Wang X, Marik J, Suen YF, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Matsuura E, Coppel RL, Gershwin ME. Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. Journal of Immunology (Baltimore, Md. : 1950). 174: 5874-83. PMID 15845458 DOI: 10.4049/Jimmunol.174.9.5874  1
2005 Pedemonte N, Sonawane ND, Taddei A, Hu J, Zegarra-Moran O, Suen YF, Robins LI, Dicus CW, Willenbring D, Nantz MH, Kurth MJ, Galietta LJ, Verkman AS. Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Molecular Pharmacology. 67: 1797-807. PMID 15722457 DOI: 10.1124/Mol.105.010959  1
2005 Kurth MJ, Olmstead MM, Haddadin MJ. Claimed 2,1-benzisoxazoles are indazalones. The Journal of Organic Chemistry. 70: 1060-2. PMID 15675871 DOI: 10.1021/Jo048153I  1
2005 Dixon S, Wang X, Lam KS, Kurth MJ. Solid-phase synthesis of quinoxaline, thiazine, and oxazine analogs through a benzyne intermediate Tetrahedron Letters. 46: 7443-7446. DOI: 10.1016/J.Tetlet.2005.08.061  1
2005 Wang X, Dixon S, Yao N, Kurth MJ, Lam KS. Microwave assisted DIC-promoted intramolecular cyclization for solid phase synthesis of trisubstituted imidazolidinones and pyrimidinones Tetrahedron Letters. 46: 5747-5750. DOI: 10.1016/J.Tetlet.2005.06.041  1
2005 Wang X, Dixon S, Kurth MJ, Lam KS. Traceless solid-phase synthesis of 1,4-disubstituted-6-nitro-3,4-dihydro- 1H-quinoline-2-ones Tetrahedron Letters. 46: 5361-5364. DOI: 10.1016/J.Tetlet.2005.06.012  1
2005 Wang X, Song A, Dixon S, Kurth MJ, Lam KS. Facile solid phase synthesis of 1,2-disubstituted-6-nitro-1,4- dihydroquinazolines using a tetrafunctional scaffold Tetrahedron Letters. 46: 427-430. DOI: 10.1016/J.Tetlet.2004.11.095  1
2004 Hwang SH, Lehman A, Cong X, Olmstead MM, Lam KS, Lebrilla CB, Kurth MJ. OBOC small-molecule combinatorial library encoded by halogenated mass-tags. Organic Letters. 6: 3829-32. PMID 15469360 DOI: 10.1021/Ol048408E  1
2004 Amano K, Leung PS, Xu Q, Marik J, Quan C, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M, Coppel RL, Gershwin ME. Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. Journal of Immunology (Baltimore, Md. : 1950). 172: 6444-52. PMID 15128836 DOI: 10.4049/Jimmunol.172.10.6444  1
2004 Hwang SH, Olmstead MM, Kurth MJ. Solid-phase synthesis of an isoxazolinopyrrole library. Journal of Combinatorial Chemistry. 6: 142-8. PMID 14714998 DOI: 10.1021/Cc034023W  1
2003 Bruggraber SF, Leung PS, Amano K, Quan C, Kurth MJ, Nantz MH, Benson GD, Van de Water J, Luketic V, Roche TE, Ansari AA, Coppel RL, Gershwin ME. Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis. Gastroenterology. 125: 1705-13. PMID 14724823 DOI: 10.1053/J.Gastro.2003.09.034  1
2003 Selmi C, Balkwill DL, Invernizzi P, Ansari AA, Coppel RL, Podda M, Leung PS, Kenny TP, Van De Water J, Nantz MH, Kurth MJ, Gershwin ME. Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium. Hepatology (Baltimore, Md.). 38: 1250-7. PMID 14578864 DOI: 10.1053/Jhep.2003.50446  1
2003 Springsteel MF, Galietta LJ, Ma T, By K, Berger GO, Yang H, Dicus CW, Choung W, Quan C, Shelat AA, Guy RK, Verkman AS, Kurth MJ, Nantz MH. Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain. Bioorganic & Medicinal Chemistry. 11: 4113-20. PMID 12927873 DOI: 10.1016/S0968-0896(03)00435-8  1
2003 Sammelson RE, Ma T, Galietta LJ, Verkman AS, Kurth MJ. 3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: synthesis and evaluation as CFTR activators. Bioorganic & Medicinal Chemistry Letters. 13: 2509-12. PMID 12852954 DOI: 10.1016/S0960-894X(03)00482-7  1
2003 Leung PS, Quan C, Park O, Van de Water J, Kurth MJ, Nantz MH, Ansari AA, Coppel RL, Lam KS, Gershwin ME. Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. Journal of Immunology (Baltimore, Md. : 1950). 170: 5326-32. PMID 12734383 DOI: 10.4049/Jimmunol.170.10.5326  1
2003 Caci E, Folli C, Zegarra-Moran O, Ma T, Springsteel MF, Sammelson RE, Nantz MH, Kurth MJ, Verkman AS, Galietta LJ. CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L180-8. PMID 12651632 DOI: 10.1152/Ajplung.00351.2002  1
2003 Park KH, Olmstead MM, Kurth MJ. Synthesis of isoxazoline-substituted symmetrical diketopiperazines Synlett. 1267-1270. DOI: 10.1055/S-2003-40333  1
2003 Price MD, Radosevich JL, Kurth MJ, Schore NE. Customized solid supports for small-molecule synthesis: Effects of crosslinking structure and degree Reactive and Functional Polymers. 55: 131-137. DOI: 10.1016/S1381-5148(02)00222-5  1
2002 Price MD, Sui JK, Kurth MJ, Schore NE. Oxazaborolidines as functional monomers: ketone reduction using polymer-supported Corey, Bakshi, and Shibata catalysts. The Journal of Organic Chemistry. 67: 8086-9. PMID 12423136 DOI: 10.1021/Jo026132N  1
2002 Price MD, Kurth MJ, Schore NE. Comparison of solid-phase and solution-phase chiral auxiliaries in the alkylation/iodolactonization sequence to gamma-butyrolactones. The Journal of Organic Chemistry. 67: 7769-73. PMID 12398501 DOI: 10.1021/Jo0260692  0.36
2002 Hwang SH, Kurth MJ. Versatile "traceless" sulfone linker for SPOS: preparation of isoxazolinopyrrole 2-carboxylates. The Journal of Organic Chemistry. 67: 6564-7. PMID 12201785 DOI: 10.1021/Jo016377K  1
2002 Kwon HJ, Smith WC, Scharon AJ, Hwang SH, Kurth MJ, Shen B. C-O bond formation by polyketide synthases. Science (New York, N.Y.). 297: 1327-30. PMID 12193782 DOI: 10.1126/Science.1073175  1
2002 Cheng WC, Liu Y, Wong M, Olmstead MM, Lam KS, Kurth MJ. Stereoselective synthesis of unnatural spiroisoxazolinoproline-based amino acids and derivatives. The Journal of Organic Chemistry. 67: 5673-7. PMID 12153267 DOI: 10.1021/Jo025611J  1
2002 Cheng WC, Kurth MJ. The sulfone linker in solid-phase synthesis: preparation of 3,5-disubstituted cyclopent-2-enones. The Journal of Organic Chemistry. 67: 4387-91. PMID 12076132 DOI: 10.1021/Jo0256843  1
2002 Huang KS, Haddadin MJ, Kurth MJ. Imidazopyridinium and pyridopyrimidium bromides: synthesis and hydrolysis. The Journal of Organic Chemistry. 67: 2382-5. PMID 11925262 DOI: 10.1021/Jo016387L  1
2002 Liu Y, Kurth MJ. Ipso substitution as a route to benzo[c]quinolizines and 4-hydroxycoumarins. The Journal of Organic Chemistry. 67: 2082-6. PMID 11925212 DOI: 10.1021/Jo0161126  1
2002 Cheng WC, Wong M, Olmstead MM, Kurth MJ. Solid-phase synthesis of novel isoxazolocyclobutanones and isoxazolinocyclobutenones. Organic Letters. 4: 741-4. PMID 11869116 DOI: 10.1021/Ol017194N  1
2002 Sammelson RE, Gurusinghe CD, Kurth JM, Olmstead MM, Kurth MJ. Synthesis of spiro-fused (C5)-isoxazolino-(C4)-pyrazolones (1-oxa-2,7,8-triazaspiro[4,4]-2,8-dien-6-ones) via 1,3-dipolar cycloaddition and cycloelimination. The Journal of Organic Chemistry. 67: 876-82. PMID 11856032 DOI: 10.1021/Jo010895D  1
2002 Gong YD, Kim SK, Yoo Se, Kurth MJ. Epimerization in intramolecular carbanilide cyclization to hydantoins: A computational study Bulletin of the Chemical Society of Japan. 75: 2477-2480. DOI: 10.1246/Bcsj.75.2477  1
2002 Cheng WC, Kurth MJ. The zincke reaction. A review Organic Preparations and Procedures International. 34: 585-608. DOI: 10.1080/00304940209355784  1
2002 Huang L, Olmstead MM, Kurth MJ. A concise synthesis of chiral 3-hydroxymethyl-5-isopropyl morpholines from valinol Organic Preparations and Procedures International. 34: 511-514. DOI: 10.1080/00304940209355773  1
2002 Price MD, Kurth MJ, Schore NE. Comparison of solid-phase and solution-phase chiral auxiliaries in the alkylation/iodolactonization sequence to γ-butyrolactones Journal of Organic Chemistry. 67: 7769-7773. DOI: 10.1021/jo0260692  1
2002 Kim P, Tsuruda JM, Olmstead MM, Eisenberg S, Kurth MJ. An intramolecular Diels-Alder route to novel tetracyclic benzo[b]thiophene derivatives Tetrahedron Letters. 43: 3963-3966. DOI: 10.1016/S0040-4039(02)00565-8  1
2002 Cheng WC, Lin CC, Kurth MJ. Dimsyl anion in the monoalkylation of solid-phase alkyl sulfones Tetrahedron Letters. 43: 2967-2970. DOI: 10.1016/S0040-4039(02)00423-9  1
2002 Hu M, Najdi SD, Wu KJ, Kurth MJ. Aqueous vinyl-insertion polymerization of lactamine-functionalized norbornene by palladium(II) chloride Tetrahedron Letters. 43: 1775-1778. DOI: 10.1016/S0040-4039(02)00098-9  1
2002 Hwang SH, Kurth MJ. 1,3-Dipolar cycloaddition of nitrile oxides to 1-phenylsulfonyl-1,3-butadienes: Synthesis of 3-(4,5-dihydroisoxazol-5-yl)pyrroles Tetrahedron Letters. 43: 53-56. DOI: 10.1016/S0040-4039(01)02069-X  1
2002 Park KH, Kurth MJ. Cyclic amino acid derivatives Tetrahedron. 58: 8629-8659. DOI: 10.1016/S0040-4020(02)00989-4  1
2002 Fan XD, Hsien YL, Kurth MJ, Krochta JM. Synthesis and characterization of lactose based resorcinol resin Journal of Applied Polymer Science. 86: 2581-2585. DOI: 10.1002/App.11216  1
2001 Sammelson RE, Kurth MJ. Carbon-carbon bond-forming solid-phase reactions. Part II. Chemical Reviews. 101: 137-202. PMID 11712191 DOI: 10.1021/Cr000086E  1
2001 Long SA, Quan C, Van de Water J, Nantz MH, Kurth MJ, Barsky D, Colvin ME, Lam KS, Coppel RL, Ansari A, Gershwin ME. Immunoreactivity of organic mimeotopes of the E2 component of pyruvate dehydrogenase: connecting xenobiotics with primary biliary cirrhosis. Journal of Immunology (Baltimore, Md. : 1950). 167: 2956-63. PMID 11509645 DOI: 10.4049/Jimmunol.167.5.2956  1
2001 Cheng WC, Olmstead MM, Kurth MJ. Vinyl sulfones in solid-phase synthesis: preparation of 4,5,6,7-tetrahydroisoindole derivatives. The Journal of Organic Chemistry. 66: 5528-33. PMID 11485478 DOI: 10.1021/Jo0156823  1
2001 Huang KS, Haddadin MJ, Olmstead MM, Kurth MJ. Synthesis and reactions of some heterocyclic azacyanines. The Journal of Organic Chemistry. 66: 1310-5. PMID 11312961 DOI: 10.1021/Jo001484K  1
2001 Wu J, Lizarzaburu ME, Kurth MJ, Liu L, Wege H, Zern MA, Nantz MH. Cationic lipid polymerization as a novel approach for constructing new DNA delivery agents. Bioconjugate Chemistry. 12: 251-7. PMID 11312686 DOI: 10.1021/Bc000097E  1
2001 Park KH, Ehrler J, Spoerri H, Kurth MJ. Preparation of a 990-member chemical compound library of hydantoin- and isoxazoline-containing heterocycles using multipin technology. Journal of Combinatorial Chemistry. 3: 171-6. PMID 11300857 DOI: 10.1021/Cc0000702  1
2001 Galietta LJ, Springsteel MF, Eda M, Niedzinski EJ, By K, Haddadin MJ, Kurth MJ, Nantz MH, Verkman AS. Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. The Journal of Biological Chemistry. 276: 19723-8. PMID 11262417 DOI: 10.1074/Jbc.M101892200  1
2001 Eda M, Kurth MJ. Polymer site-site interactions: Mechanistic implication in the solid-phase Zincke reaction Chemical Communications. 723-724. DOI: 10.1039/B009886H  1
2001 Alonso C, Olmstead MM, Nantz MH, Kurth MJ. Competitive intramolecular nucleophilic aromatic substitution: A new route to coumarins Chemical Communications. 639-640. DOI: 10.1039/B009172N  1
2001 Sammelson RE, Kurth MJ. Oxidation-Cope elimination: A REM-resin cleavage protocol for the solid-phase synthesis of hydroxylamines Tetrahedron Letters. 42: 3419-3422. DOI: 10.1016/S0040-4039(01)00477-4  1
2001 Eda M, Kurth MJ. Solid-phase Zincke route to pyridinium, tetrahydropyridine, and piperidine derivatives: Vesamicol analogs Tetrahedron Letters. 42: 2063-2068. DOI: 10.1016/S0040-4039(00)02351-0  1
2001 Park KH, Kurth TM, Olmstead MM, Kurth MJ. Regio- and diastereoselective synthesis of cyclic amino esters Tetrahedron Letters. 42: 991-992. DOI: 10.1016/S0040-4039(00)02217-6  1
2001 By K, Kelly PA, Kurth MJ, Olmstead MM, Nantz MH. Synthesis of a C(4)-C(9) eleutheside template from D-glucal Tetrahedron. 57: 1183-1187. DOI: 10.1016/S0040-4020(00)01117-0  1
2001 Zhou WJ, Kurth MJ. Synthesis of a novel pH-responding polymer with pendant barbituric acid moieties Polymer. 42: 345-349. DOI: 10.1016/S0032-3861(00)00355-4  1
2001 Fan XD, Hsieh YL, Krochta JM, Kurth MJ. Study on molecular interaction behavior, and thermal and mechanical properties of polyacrylic acid and lactose blends Journal of Applied Polymer Science. 82: 1921-1927. DOI: 10.1002/App.2037  1
2000 Sammelson RE, Olmstead MM, Haddadin MJ, Kurth MJ. 1,2,4,5-Tetrazines as oxidant and reactant with DBU: An unexpected formation of a novel fused tetraheterocyclic azepine The Journal of Organic Chemistry. 65: 9265-7. PMID 11149886 DOI: 10.1021/Jo001363K  1
2000 Han JH, Krochta JM, Hsieh YL, Kurth MJ. Mechanism and characteristics of protein release from lactitol-based cross-linked hydrogel. Journal of Agricultural and Food Chemistry. 48: 5658-65. PMID 11087535 DOI: 10.1021/Jf0002239  1
2000 Han JH, Krochta JM, Kurth MJ, Hsieh YL. Lactitol-based poly(ether polyol) hydrogels for controlled release chemical and drug delivery systems. Journal of Agricultural and Food Chemistry. 48: 5278-82. PMID 11087472 DOI: 10.1021/Jf991329A  1
2000 Illek B, Lizarzaburu ME, Lee V, Nantz MH, Kurth MJ, Fischer H. Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin. American Journal of Physiology. Cell Physiology. 279: C1838-46. PMID 11078699 DOI: 10.1152/Ajpcell.2000.279.6.C1838  1
2000 Eda M, Kurth MJ, Nantz MH. The solid-phase Zincke reaction: preparation of omega-hydroxy pyridinium salts in the search for CFTR activation. The Journal of Organic Chemistry. 65: 5131-5. PMID 10993337 DOI: 10.1021/Jo0001636  1
2000 Kim P, Nantz MH, Kurth MJ, Olmstead MM. Intramolecular Diels-Alder Reactions of Decatrienoates: Remote Stereocontrol and Conformational Activation(1). Organic Letters. 2: 1831-1834. PMID 10891169 DOI: 10.1021/Ol005886Q  1
2000 Park KH, Kurth MJ. Diastereoselective synthesis of hydantoin- and isoxazoline-substituted dispirocyclobutanoids. The Journal of Organic Chemistry. 65: 3520-4. PMID 10843640 DOI: 10.1021/Jo000152C  1
2000 Huang KS, Lee EH, Olmstead MM, Kurth MJ. Sequential 1,3-dipolar cycloadditions in the synthesis of bis-isoxazolo substituted piperidinones The Journal of Organic Chemistry. 65: 499-503. PMID 10813963 DOI: 10.1021/Jo991418M  1
2000 Sammelson RE, Miller RB, Kurth MJ. Linear tetraheterocycles composed of both bidentate diisoxazole and bidentate isoxazole--furyl/thienyl/pyridyl motifs The Journal of Organic Chemistry. 65: 2225-8. PMID 10774051 DOI: 10.1021/Jo991551E  1
2000 Park KH, Kurth MJ. Cyclo-elimination release strategies applied to solid-phase organic synthesis in drug discovery Drugs of the Future. 25: 1265-1294. DOI: 10.1358/dof.2000.025.12.616456  1
2000 Park KH, Kurth MJ. Solid-phase synthesis of novel achiral hydantoin- and isoxazoline-substituted dispirocyclobutanoids Chemical Communications. 1835-1836. DOI: 10.1039/B004033I  1
2000 Sammelson RE, Miller RB, Kurth MJ. Linear tetraheterocycles composed of both bidentate diisoxazole and bidentate isoxazole-furyl/thienyl/pyridyl/motifs Journal of Organic Chemistry. 65: 2225-2228. DOI: 10.1021/jo991551e  1
2000 Park KH, Kurth MJ. Hydantoin formation by cyclo-elimination: Reactivity difference between Merrifield- and Wang-derived resins Tetrahedron Letters. 41: 7409-7413. DOI: 10.1016/S0040-4039(00)01073-X  1
2000 Alonso C, Nantz MH, Kurth MJ. β-Dimethylphenylsilylethyl esters: A linker for solid-phase chemistry Tetrahedron Letters. 41: 5617-5622. DOI: 10.1016/S0040-4039(00)00909-6  1
2000 Haddadin MJ, Kurth MJ, Olmstead MM. One-step synthesis of new heterocyclic azacyanines Tetrahedron Letters. 41: 5613-5616. DOI: 10.1016/S0040-4039(00)00908-4  1
2000 Kim P, Olmstead MM, Nantz MH, Kurth MJ. Knoevenagel condensations of β-hemiacetyl esters Tetrahedron Letters. 41: 4029-4032. DOI: 10.1016/S0040-4039(00)00581-5  1
2000 Kantorowski EJ, Kurth MJ. Expansion to seven-membered rings Tetrahedron. 56: 4317-4353. DOI: 10.1016/S0040-4020(00)00218-0  1
2000 Chacon D, Hsieh YL, Kurth MJ, Krochta JM. Swelling and protein absorption/desorption of thermo-sensitive lactitol- based polyether polyol hydrogels Polymer. 41: 8257-8262. DOI: 10.1016/S0032-3861(00)00208-1  1
1999 Watt KC, Morin DM, Kurth MJ, Mercer RS, Plopper CG, Buckpitt AR. Glutathione conjugation of electrophilic metabolites of 1-nitronaphthalene in rat tracheobronchial airways and liver: identification by mass spectrometry and proton nuclear magnetic resonance spectroscopy. Chemical Research in Toxicology. 12: 831-9. PMID 10490505 DOI: 10.1021/Tx990023V  1
1999 Lizarzaburu ME, Jones RM, Nantz MH, Kurth MJ. Multi-gram synthesis of dimyristoyl pentaerythritol Organic Preparations and Procedures International. 31: 440-442. DOI: 10.1080/00304949909355735  1
1999 Zhou WJ, Kurth MJ, Hsieh YL, Krochta JM. Synthesis and characterization of new styrene main-chain polymer with pendant lactose moiety through urea linkage Macromolecules. 32: 5507-5513. DOI: 10.1021/Ma990397V  1
1999 Park KH, Kurth MJ. Solid-phase synthesis of novel heterocycles containing thiohydantoin and isoxazole rings Journal of Organic Chemistry. 64: 9297-9300. DOI: 10.1021/Jo991166P  1
1999 Cheng WC, Halm C, Evarts JB, Olmstead MM, Kurth MJ. Allylic sulfones in solid-phase synthesis: Preparation of cyclobutylidenes Journal of Organic Chemistry. 64: 8557-8562. DOI: 10.1021/Jo990954B  1
1999 Lizarzaburu ME, Kurth MJ, Nantz MH. A versatile synthesis of tetraester polyamine lipids for gene transfection Tetrahedron Letters. 40: 8985-8988. DOI: 10.1016/S0040-4039(99)01934-6  1
1999 Park KH, Kurth MJ. An uncatalyzed cyclo-elimination process for the release of N3- alkylated hydantoins from solid-phase: Synthesis of novel isoxazoloimidazolidinediones Tetrahedron Letters. 40: 5841-5844. DOI: 10.1016/S0040-4039(99)01145-4  1
1999 Lorsbach BA, Kurth MJ. Carbon-carbon bond forming solid-phase reactions Chemical Reviews. 99: 1549-1581.  1
1998 Park KH, Olmstead MM, Kurth MJ. Diastereoselective Synthesis of Cyclopentanoids with Hydantoin and Isoxazoline Substituents. The Journal of Organic Chemistry. 63: 113-117. PMID 11674050 DOI: 10.1021/Jo9714831  1
1998 Kantorowski EJ, Borhan B, Nazarian S, Kurth MJ. Cyclopropylcarbinyl radical-mediated ring expansion to seven-membered carbocycles Tetrahedron Letters. 39: 2483-2486. DOI: 10.1016/S0040-4039(98)00311-6  1
1998 Najdi S, Park KH, Olmstead MM, Kurth MJ. Synthesis of hexahydro-1H-pyrrolo[1,2-c]imidazole derivatives by sequential azomethine ylide cycloaddition and urea cyclization reactions Tetrahedron Letters. 39: 1685-1688. DOI: 10.1016/S0040-4039(98)00125-7  1
1998 Montierth JM, DeMario DR, Kurth MJ, Schore NE. The polymer-supported Cadiot-Chodkiewicz coupling of acetylenes to produce unsymmetrical diynes Tetrahedron. 54: 11741-11748. DOI: 10.1016/S0040-4020(98)83035-4  1
1997 Kantorowski EJ, Kurth MJ. Dipolar cycloadditions in solid-phase organic synthesis (SPOS). Molecular Diversity. 2: 207-16. PMID 9249756 DOI: 10.1007/Bf01715636  1
1997 Spitzer JL, Kurth MJ, Schore NE, Najdi SD. Polymer-supported synthesis as a tool for improving chemoselectivity: Pauson-Khand reaction Tetrahedron. 53: 6791-6808. DOI: 10.1016/S0040-4020(97)00386-4  1
1995 Borhan B, Mebrahtu T, Nazarian S, Kurth MJ, Hammock BD. Improved radiolabeled substrates for soluble epoxide hydrolase. Analytical Biochemistry. 231: 188-200. PMID 8678300 DOI: 10.1006/Abio.1995.1520  1
1995 Borhan B, Ko Y, Mackay C, Wilson BW, Kurth MJ, Hammock BD. Development of surrogate substrates for neuropathy target esterase. Biochimica Et Biophysica Acta. 1250: 171-82. PMID 7632722 DOI: 10.1016/0167-4838(95)00058-3  1
1995 Borhan B, Jones AD, Pinot F, Grant DF, Kurth MJ, Hammock BD. Mechanism of soluble epoxide hydrolase. Formation of an alpha-hydroxy ester-enzyme intermediate through Asp-333. The Journal of Biological Chemistry. 270: 26923-30. PMID 7592938 DOI: 10.1074/Jbc.270.45.26923  1
1995 Borhan B, Wilson JA, Gasch MJ, Ko Y, Kurth DM, Kurth MJ. Suspension copolymerization as a route to trityl-functionalized polystyrene polymers The Journal of Organic Chemistry. 60: 7375-7378. DOI: 10.1021/Jo00127A057  1
1994 Moon Hs, Schore NE, Kurth MJ. A polymer-supported C2-symmetric chiral auxiliary: Preparation of non-racemic 3,5-disubstituted-γ-butyrolactones Tetrahedron Letters. 35: 8915-8918. DOI: 10.1016/0040-4039(94)88388-2  1
1993 Marco MP, Nasiri M, Kurth MJ, Hammock BD. Enzyme-linked immunosorbent assay for the specific detection of the mercapturic acid metabolites of naphthalene. Chemical Research in Toxicology. 6: 284-93. PMID 8318650 DOI: 10.1021/Tx00033A006  0.56
1993 Borhan B, Nourooz-Zadeh J, Uematsu T, Hammock BD, Kurth MJ. Stereochemical aspects of cytosolic epoxide hydrolase hydration of methyl diepoxystearates Tetrahedron. 49: 2601-2612. DOI: 10.1016/S0040-4020(01)86339-0  1
1992 Nourooz-Zadeh J, Uematsu T, Borhan B, Kurth MJ, Hammock BD. Characterization of the cytosolic epoxide hydrolase-catalyzed hydration products from 9,10:12,13-diepoxy stearic esters. Archives of Biochemistry and Biophysics. 294: 675-85. PMID 1567223 DOI: 10.1016/0003-9861(92)90741-E  1
1992 Beebe X, Schore NE, Kurth MJ. Polymer-supported synthesis of 2,5-disubstituted tetrahydrofurans Journal of the American Chemical Society. 114: 10061-10062. DOI: 10.1021/Ja00051A048  1
1991 Miller MG, McEuen SF, Nasiri M, Eck DL, Kurth MJ. Application of ELISA techniques to metabolic disposition studies for 1,3-dinitrobenzene: comparison with HPLC and radiochemical methods. Chemical Research in Toxicology. 4: 324-9. PMID 1912316 DOI: 10.1021/Tx00021A011  1
1991 Rae Kim H, Jin Kim H, Duffy JL, Olmstead MM, Ruhlandt-Senge K, Kurth MJ. Double diastereoselectivity in the intramolecular nitrile oxide-olefin cycloaddition (INOC) reaction Tetrahedron Letters. 32: 4259-4262. DOI: 10.1016/S0040-4039(00)92143-9  1
1988 Kurth MJ, Green CB, Mount ME, Jackson DY. Polypeptide fluoroacetate derivatives. Synthesis and 19F n.m.r. International Journal of Peptide and Protein Research. 31: 388-95. PMID 3391744 DOI: 10.1111/J.1399-3011.1988.Tb00047.X  1
1987 Kurth MJ, Soares CJ. Asymmetric aza-Claisen rearrangement: Synthesis of (+)-dihydropallescensin-2 [(+)-penlanpallescensin] Tetrahedron Letters. 28: 1031-1034. DOI: 10.1016/S0040-4039(00)95903-3  1
1985 Kurth MJ, Bruins P, Mount ME. Diphacinone: 13C NMR as a predictive tool in tricarbonyl chemistry Tetrahedron Letters. 26: 4883-4886. DOI: 10.1016/S0040-4039(00)94976-1  1
1984 Kurth MJ, Yu CM. The dianion Claisen rearrangement of β-hydroxy esters Tetrahedron Letters. 25: 5003-5006. DOI: 10.1016/S0040-4039(01)91102-5  1
1983 Hoye TR, Kurth MJ. Preparation of d,l-megaphone intermediates Tetrahedron Letters. 24: 4769-4772. DOI: 10.1016/S0040-4039(00)94003-6  1
1981 Oppolzer W, Kurth M, Reichlin D, Moffatt F. A reinvestigation of asymmetric induction in diels-alder reactions to chiral acrylates. Tetrahedron Letters. 22: 2545-2548. DOI: 10.1016/S0040-4039(01)90516-7  1
1981 Hoye TR, Kurth MJ, Lo V. Triphenylcarbenium and tris(P-bromophenyl)ammoniumyl ion induced lactonizations of (ω-benzyloxy and ω-P-methoxybenzyloxy methyl esters Tetrahedron Letters. 22: 815-818. DOI: 10.1016/0040-4039(81)80004-4  1
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