Mitesh Nagar - Publications

Affiliations: 
Dalhousie University, Halifax, Nova Scotia, Canada 

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Fetter CM, Morrison ZA, Nagar M, Douglas CD, Bearne SL. Altering the Y137K164K166 triad of mandelate racemase and its effect on the observed pK of the brønsted base catalysts. Archives of Biochemistry and Biophysics. PMID 30935886 DOI: 10.1016/J.Abb.2019.03.011  0.84
2018 Nagar M, Kumar H, Bearne SL. A platform for chemical modification of mandelate racemase: characterization of the C92S/C264S and γ-thialysine 166 variants. Protein Engineering, Design & Selection : Peds. PMID 29850884 DOI: 10.1093/Protein/Gzy011  0.84
2015 Nagar M, Bearne SL. An additional role for the Brønsted acid-base catalysts of mandelate racemase in transition state stabilization. Biochemistry. 54: 6743-52. PMID 26480244 DOI: 10.1021/Acs.Biochem.5B00982  0.64
2015 Nagar M, Wyatt BN, St Maurice M, Bearne SL. Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies. Biochemistry. 54: 2747-57. PMID 25844917 DOI: 10.1021/Acs.Biochem.5B00221  0.64
2014 Nagar M, Lietzan AD, St Maurice M, Bearne SL. Potent inhibition of mandelate racemase by a fluorinated substrate-product analogue with a novel binding mode. Biochemistry. 53: 1169-78. PMID 24472022 DOI: 10.1021/Bi401703H  0.64
2014 Harty M, Nagar M, Atkinson L, Legay CM, Derksen DJ, Bearne SL. Inhibition of serine and proline racemases by substrate-product analogues. Bioorganic & Medicinal Chemistry Letters. 24: 390-3. PMID 24314397 DOI: 10.1016/J.Bmcl.2013.10.061  0.64
2012 Lietzan AD, Nagar M, Pellmann EA, Bourque JR, Bearne SL, St Maurice M. Structure of mandelate racemase with bound intermediate analogues benzohydroxamate and cupferron. Biochemistry. 51: 1160-70. PMID 22264153 DOI: 10.1021/Bi2018514  0.64
2011 Nagar M, Narmandakh A, Khalak Y, Bearne SL. Redefining the minimal substrate tolerance of mandelate racemase. Racemization of trifluorolactate. Biochemistry. 50: 8846-52. PMID 21894901 DOI: 10.1021/Bi201188J  0.64
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