Thomas J. Kodadek, Ph.D. - Publications

Chemistry and Cancer Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Chemical Biology

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Year Citation  Score
2020 Paciaroni NG, Ndungu JM, Kodadek T. Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy. Chemical Communications (Cambridge, England). PMID 32215395 DOI: 10.1039/D0Cc01474E  0.36
2019 Doran TM, Dickson P, Ndungu JM, Ge P, Suponitsky-Kroyter I, An H, Kodadek T. Synthesis and screening of bead-displayed combinatorial libraries. Methods in Enzymology. 622: 91-127. PMID 31155067 DOI: 10.1016/Bs.Mie.2019.02.005  0.68
2018 Feng N, Simanski S, Islam K, Hynan LS, Kodadek T, German DC. Antibody biomarker for de novo Parkinson disease: attempted validation. Npj Parkinson's Disease. 4: 28. PMID 30211310 DOI: 10.1038/S41531-018-0064-2  0.56
2018 Erharuyi O, Simanski S, McEnaney PJ, Kodadek T. Screening one bead one compound libraries against serum using a flow cytometer: Determination of the minimum antibody concentration required for ligand discovery. Bioorganic & Medicinal Chemistry Letters. PMID 29395976 DOI: 10.1016/J.Bmcl.2018.01.033  0.56
2018 Pels K, Dickson P, An H, Kodadek T. DNA-compatible solid-phase combinatorial synthesis of β-cyanoacrylamides and related electrophiles. Acs Combinatorial Science. PMID 29298042 DOI: 10.1021/Acscombsci.7B00169  0.4
2017 Wu H, An H, Mo SC, Kodadek T. Asymmetric synthesis of vinylogous β-amino acids and their incorporation into mixed backbone oligomers. Organic & Biomolecular Chemistry. PMID 28346549 DOI: 10.1039/C7Ob00333A  0.52
2017 Trader DJ, Simanski S, Dickson P, Kodadek T. Establishment of a suite of assays that support the discovery of proteasome stimulators. Biochimica Et Biophysica Acta. 1861: 892-899. PMID 28065760 DOI: 10.1016/J.Bbagen.2017.01.003  0.56
2016 Mendes KR, Malone ML, Ndungu JM, Suponitsky-Kroyter I, Cavett VJ, McEnaney PJ, MacConnell AB, Doran TM, Ronacher K, Stanley K, Utset O, Walzl G, Paegel BM, Kodadek T. High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections. Acs Chemical Biology. PMID 27957856 DOI: 10.1021/Acschembio.6B00855  0.68
2016 Wu H, Mousseau G, Mediouni S, Valente ST, Kodadek T. Cell-Permeable Peptides Containing Cycloalanine Residues. Angewandte Chemie (International Ed. in English). PMID 27529332 DOI: 10.1002/Anie.201605745  0.52
2016 Wu SY, Nin DS, Lee AY, Simanski S, Kodadek T, Chiang CM. BRD4 Phosphorylation Regulates HPV E2-Mediated Viral Transcription, Origin Replication, and Cellular MMP-9 Expression. Cell Reports. PMID 27477287 DOI: 10.1016/J.Celrep.2016.07.001  0.8
2016 Doran TM, Morimoto J, Simanski S, Koesema EJ, Clark LF, Pels K, Stoops SL, Pugliese A, Skyler JS, Kodadek T. Discovery of Phosphorylated Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus. Cell Chemical Biology. PMID 27185639 DOI: 10.1016/J.Chembiol.2016.04.006  0.68
2016 Sarma BK, Liu X, Kodadek T. Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library. Bioorganic & Medicinal Chemistry. PMID 27160052 DOI: 10.1016/J.Bmc.2016.04.047  0.68
2016 Doran TM, Sarkar M, Kodadek T. Chemical Tools to Monitor and Manipulate Adaptive Immune Responses. Journal of the American Chemical Society. PMID 27115249 DOI: 10.1021/Jacs.6B02954  0.8
2016 Kodadek T, McEnaney PJ. Towards vast libraries of scaffold-diverse, conformationally constrained oligomers. Chemical Communications (Cambridge, England). PMID 26996593 DOI: 10.1039/C6Cc00617E  0.52
2016 Sarkar M, Liu Y, Qi J, Peng H, Morimoto J, Rader C, Chiorazzi N, Kodadek T. Targeting stereotyped B cell receptors from chronic lymphocytic leukemia patients with synthetic antigen surrogates. The Journal of Biological Chemistry. PMID 26851280 DOI: 10.1074/Jbc.M115.701656  0.8
2015 Doran TM, Morimoto J, Simanski S, McEnaney PJ, Kodadek T. Reliable diagnosis of murine type 1 diabetes using a panel of autoantigens and "antigen surrogates" mounted onto a liquid array. Molecular Biosystems. 11: 3156-63. PMID 26390856 DOI: 10.1039/C5Mb00521C  0.8
2015 Mendes K, Ndungu JM, Clark LF, Kodadek T. Optimization of the Magnetic Recovery of Hits from One-Bead-One-Compound Library Screens. Acs Combinatorial Science. 17: 506-17. PMID 26221913 DOI: 10.1021/Acscombsci.5B00090  0.8
2015 Li X, Patterson JT, Sarkar M, Pedzisa L, Kodadek T, Roush WR, Rader C. Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues. Bioconjugate Chemistry. PMID 26161903 DOI: 10.1021/Acs.Bioconjchem.5B00244  0.8
2015 Doran TM, Gao Y, Simanski S, McEnaney P, Kodadek T. High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type 1 diabetes autoantibodies. Bioorganic & Medicinal Chemistry Letters. 25: 4910-7. PMID 26067174 DOI: 10.1016/J.Bmcl.2015.05.046  0.8
2015 Trader DJ, Simanski S, Kodadek T. A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor rpn13 is toxic to multiple myeloma cells. Journal of the American Chemical Society. 137: 6312-9. PMID 25914958 DOI: 10.1021/Jacs.5B02069  0.56
2015 Gao Y, Kodadek T. Direct comparison of linear and macrocyclic compound libraries as a source of protein ligands. Acs Combinatorial Science. 17: 190-5. PMID 25623285 DOI: 10.1021/Co500161C  0.8
2015 Cravatt BF, Kodadek T. Editorial overview: Omics: Methods to monitor and manipulate biological systems: recent advances in 'omics'. Current Opinion in Chemical Biology. 24: v-vii. PMID 25549533 DOI: 10.1016/J.Cbpa.2014.12.023  0.8
2015 Doran TM, Simanski S, Kodadek T. Discovery of native autoantigens via antigen surrogate technology: application to type 1 diabetes. Acs Chemical Biology. 10: 401-12. PMID 25474415 DOI: 10.1021/Cb5007618  0.8
2015 Gao Y, Amar S, Pahwa S, Fields G, Kodadek T. Rapid lead discovery through iterative screening of one bead one compound libraries. Acs Combinatorial Science. 17: 49-59. PMID 25434974 DOI: 10.1021/Co500154E  0.8
2015 Sarma BK, Liu X, Wu H, Gao Y, Kodadek T. Solid phase synthesis of 1,3,4-oxadiazin-5 (6R)-one and 1,3,4-oxadiazol-2-one scaffolds from acyl hydrazides. Organic & Biomolecular Chemistry. 13: 59-63. PMID 25354697 DOI: 10.1039/C4Ob01883D  0.8
2015 Morimoto J, Kodadek T. Synthesis of a large library of macrocyclic peptides containing multiple and diverse N-alkylated residues Molecular Biosystems. 11: 2770-2779. DOI: 10.1039/C5Mb00308C  0.8
2015 Pels K, Kodadek T. Solid-phase synthesis of diverse peptide tertiary amides by reductive amination Acs Combinatorial Science. 17: 152-155. DOI: 10.1021/Acscombsci.5B00007  0.8
2014 Sarkar M, Liu Y, Morimoto J, Peng H, Aquino C, Rader C, Chiorazzi N, Kodadek T. Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates. Chemistry & Biology. 21: 1670-9. PMID 25467125 DOI: 10.1016/J.Chembiol.2014.10.010  0.8
2014 Kodadek T. Chemical tools to monitor and manipulate the adaptive immune system Chemistry and Biology. 21: 1066-1074. PMID 25237855 DOI: 10.1016/J.Chembiol.2014.07.009  0.8
2014 Morimoto J, Sarkar M, Kenrick S, Kodadek T. Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands. Bioconjugate Chemistry. 25: 1479-91. PMID 25073654 DOI: 10.1021/Bc500226J  0.8
2014 Gao Y, Kodadek T. Split-and-pool synthesis and characterization of peptide tertiary amide library Journal of Visualized Experiments. PMID 24998250 DOI: 10.3791/51299  0.8
2014 Suwal S, Kodadek T. Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units Organic and Biomolecular Chemistry. 12: 5831-5834. PMID 24976298 DOI: 10.1039/C4Ob00829D  0.8
2014 Doran TM, Gao Y, Mendes K, Dean S, Simanski S, Kodadek T. Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits. Acs Combinatorial Science. 16: 259-70. PMID 24749624 DOI: 10.1021/Co500030F  0.8
2014 Quan J, Lakhanpal A, Reddy MM, Zaman S, Li QZ, German DC, Olsen NJ, Kodadek T, Karp DR. Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates. Journal of Immunological Methods. 402: 23-34. PMID 24269750 DOI: 10.1016/J.Jim.2013.11.004  0.8
2014 Doran TM, Kodadek T. A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions. Acs Chemical Biology. 9: 339-46. PMID 24245981 DOI: 10.1021/Cb400806R  0.8
2014 Vanderstichele H, Kodadek T. Roadblocks for integration of novel biomarker concepts into clinical routine: The peptoid approach Alzheimer's Research and Therapy. 6. DOI: 10.1186/Alzrt253  0.8
2013 Kodadek T. A jack of all trades to combat drug-resistant gram-negative bacteria Chemistry and Biology. 20: 1202-1203. PMID 24210003 DOI: 10.1016/J.Chembiol.2013.10.006  0.8
2013 Rzuczek SG, Gao Y, Tang ZZ, Thornton CA, Kodadek T, Disney MD. Features of modularly assembled compounds that impart bioactivity against an RNA target. Acs Chemical Biology. 8: 2312-21. PMID 24032410 DOI: 10.1021/Cb400265Y  0.8
2013 Clark LF, Kodadek T. Advances in blood-based protein biomarkers for Alzheimer's disease. Alzheimer's Research & Therapy. 5: 18. PMID 23659521 DOI: 10.1186/Alzrt172  0.8
2013 Sarkar M, Pascal BD, Steckler C, Aquino C, Micalizio GC, Kodadek T, Chalmers MJ. Decoding split and pool combinatorial libraries with electron-transfer dissociation tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 24: 1026-36. PMID 23636859 DOI: 10.1007/S13361-013-0633-X  0.8
2013 Gao Y, Kodadek T. Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides Chemistry and Biology. 20: 360-369. PMID 23521794 DOI: 10.1016/J.Chembiol.2013.01.013  0.8
2013 Raveendra BL, Wu H, Baccala R, Reddy MM, Schilke J, Bennett JL, Theofilopoulos AN, Kodadek T. Discovery of peptoid ligands for anti-aquaporin 4 antibodies. Chemistry & Biology. 20: 351-9. PMID 23521793 DOI: 10.1016/J.Chembiol.2012.12.009  0.8
2013 Suwal S, Kodadek T. Synthesis of libraries of peptidomimetic compounds containing a 2-oxopiperazine unit in the main chain Organic and Biomolecular Chemistry. 11: 2088-2092. PMID 23440085 DOI: 10.1039/C3Ob27476D  0.8
2012 Sarma BK, Kodadek T. Submonomer synthesis of a hybrid peptoid-azapeptoid library Acs Combinatorial Science. 14: 558-564. PMID 22958123 DOI: 10.1021/Co3000852  0.8
2012 Liu X, Dix M, Speers AE, Bachovchin DA, Zuhl AM, Cravatt BF, Kodadek TJ. Rapid development of a potent photo-triggered inhibitor of the serine hydrolase RBBP9. Chembiochem : a European Journal of Chemical Biology. 13: 2082-93. PMID 22907802 DOI: 10.1002/Cbic.201200445  0.8
2012 Simpson LS, Kodadek T. A Cleavable Scaffold Strategy for the Synthesis of One-Bead One-Compound Cyclic Peptoid Libraries That Can Be Sequenced By Tandem Mass Spectrometry. Tetrahedron Letters. 53: 2341-2344. PMID 22736872 DOI: 10.1016/J.Tetlet.2012.02.112  0.8
2012 Aditya A, Kodadek T. Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries Acs Combinatorial Science. 14: 164-169. PMID 22320121 DOI: 10.1021/Co200195T  0.8
2012 Aquino C, Sarkar M, Chalmers MJ, Mendes K, Kodadek T, Micalizio GC. A biomimetic polyketide-inspired approach to small-molecule ligand discovery. Nature Chemistry. 4: 99-104. PMID 22270625 DOI: 10.1038/Nchem.1200  0.8
2011 Chen X, Wu J, Luo Y, Liang X, Supnet C, Kim MW, Lotz GP, Yang G, Muchowski PJ, Kodadek T, Bezprozvanny I. Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease. Chemistry & Biology. 18: 1113-25. PMID 21944750 DOI: 10.1016/J.Chembiol.2011.06.010  0.8
2011 Kanta Sarma B, Yousufuddin M, Kodadek T. Acyl hydrazides as peptoid sub-monomers Chemical Communications. 47: 10590-10592. PMID 21892506 DOI: 10.1039/C1Cc12750K  0.8
2011 Cai D, Lee AY, Chiang CM, Kodadek T. Peptoid ligands that bind selectively to phosphoproteins Bioorganic and Medicinal Chemistry Letters. 21: 4960-4964. PMID 21742492 DOI: 10.1016/J.Bmcl.2011.06.011  0.8
2011 Kodadek T. The rise, fall and reinvention of combinatorial chemistry Chemical Communications. 47: 9757-9763. PMID 21701754 DOI: 10.1039/C1Cc12102B  0.8
2011 Reddy MM, Wilson R, Wilson J, Connell S, Gocke A, Hynan L, German D, Kodadek T. Identification of candidate IgG biomarkers for alzheimer's disease via combinatorial library screening Cell. 144: 132-142. PMID 21215375 DOI: 10.1016/J.Cell.2010.11.054  0.8
2011 Mendes K, Kodadek T. PDZ dimerization brings proteins together Chemistry and Biology. 18: 1071-1072. DOI: 10.1016/J.Chembiol.2011.09.001  0.8
2010 Lee J, Reddy MM, Kodadek T. Discovery Of An Orexin Receptor Positive Potentiator. Chemical Science (Royal Society of Chemistry : 2010). 1. PMID 24409338 DOI: 10.1039/C0Sc00197J  0.8
2010 De León-Rodríguez LM, Lubag A, Udugamasooriya DG, Proneth B, Brekken RA, Sun X, Kodadek T, Dean Sherry A. MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting. Journal of the American Chemical Society. 132: 12829-31. PMID 20795620 DOI: 10.1021/Ja105563A  0.8
2010 Kodadek T. Synthetic receptors with antibody-like binding affinities Current Opinion in Chemical Biology. 14: 713-720. PMID 20674471 DOI: 10.1016/J.Cbpa.2010.07.001  0.8
2010 Kodadek T. Development of antibody surrogates for the treatment of cancers and autoimmune disease Current Opinion in Chemical Biology. 14: 721-727. PMID 20674470 DOI: 10.1016/J.Cbpa.2010.07.002  0.8
2010 Lynn KD, Udugamasooriya DG, Roland CL, Castrillon DH, Kodadek TJ, Brekken RA. GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer. Bmc Cancer. 10: 397. PMID 20673348 DOI: 10.1186/1471-2407-10-397  0.8
2010 Cai D, Shames DS, Raso MG, Xie Y, Kim YH, Pollack JR, Girard L, Sullivan JP, Gao B, Peyton M, Nanjundan M, Byers L, Heymach J, Mills G, Gazdar AF, ... ... Kodadek T, et al. Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. Cancer Research. 70: 6477-85. PMID 20663904 DOI: 10.1158/0008-5472.Can-10-0005  0.8
2010 Cravatt BF, Kodadek T. The interface of chemical biology and the nervous system (related to the NIDA Chemical Genomics Symposium). Molecular Biosystems. 6: 1337. PMID 20582378 DOI: 10.1039/C0Mb90009E  0.8
2010 Kodadek T, Cai D. Chemistry and biology of orexin signaling Molecular Biosystems. 6: 1366-1375. PMID 20532299 DOI: 10.1039/C003468A  0.8
2010 Lee J, Udugamasooriya DG, Lim HS, Kodadek T. Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates. Nature Chemical Biology. 6: 258-60. PMID 20228793 DOI: 10.1038/Nchembio.333  0.8
2010 Astle JM, Simpson LS, Huang Y, Reddy MM, Wilson R, Connell S, Wilson J, Kodadek T. Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries. Chemistry & Biology. 17: 38-45. PMID 20142039 DOI: 10.1016/J.Chembiol.2009.12.015  0.8
2010 Archer CT, Kodadek T. The hydrophobic patch of ubiquitin is required to protect transactivator-promoter complexes from destabilization by the proteasomal ATPases. Nucleic Acids Research. 38: 789-96. PMID 19939937 DOI: 10.1093/Nar/Gkp1066  0.8
2010 Kodadek T. No splicing, no dicing: Non-proteolytic roles of the ubiquitin-proteasome system in transcription Journal of Biological Chemistry. 285: 2221-2226. DOI: 10.1074/Jbc.R109.077883  0.8
2010 Kodadek T. Rethinking screening Nature Chemical Biology. 6: 162-165. DOI: 10.1038/nchembio.303  0.8
2009 Kodadek T. Protein binding: Antibody surrogates click into place Nature Chemistry. 1: 183-185. PMID 21378844 DOI: 10.1038/Nchem.228  0.8
2009 Qi X, Astle J, Kodadek T. Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beads Molecular Biosystems. 6: 102-107. PMID 20024071 DOI: 10.1039/B915611A  0.8
2009 Gocke AR, Udugamasooriya DG, Archer CT, Lee J, Kodadek T. Isolation of antagonists of antigen-specific autoimmune T cell proliferation. Chemistry & Biology. 16: 1133-9. PMID 19942136 DOI: 10.1016/J.Chembiol.2009.10.011  0.8
2009 Kim YC, Wu SY, Lim HS, Chiang CM, Kodadek T. Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator-promoter complex by the proteasomal ATPases Journal of Biological Chemistry. 284: 34522-34530. PMID 19846554 DOI: 10.1074/Jbc.M109.017277  0.8
2009 Liu B, Kodadek T. Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides Journal of Medicinal Chemistry. 52: 4604-4612. PMID 19610652 DOI: 10.1021/Jm9002999  0.8
2009 Wilkinson MB, Xiao G, Kumar A, LaPlant Q, Renthal W, Sikder D, Kodadek TJ, Nestler EJ. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7820-32. PMID 19535594 DOI: 10.1523/Jneurosci.0932-09.2009  0.8
2009 Zuckermann RN, Kodadek T. Peptoids as potential therapeutics. Current Opinion in Molecular Therapeutics. 11: 299-307. PMID 19479663  0.8
2009 Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, Russo SJ, Vialou V, Chakravarty S, Kodadek TJ, Stack A, et al. Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron. 62: 335-48. PMID 19447090 DOI: 10.1016/J.Neuron.2009.03.026  0.8
2009 Lim HS, Muralidhar Reddy M, Xiao X, Wilson J, Wilson R, Connell S, Kodadek T. Rapid identification of improved protein ligands using peptoid microarrays Bioorganic and Medicinal Chemistry Letters. 19: 3866-3869. PMID 19380225 DOI: 10.1016/J.Bmcl.2009.03.153  0.8
2009 Simpson LS, Burdine L, Dutta AK, Feranchak AP, Kodadek T. Selective toxin sequestrants for the treatment of bacterial infections. Journal of the American Chemical Society. 131: 5760-2. PMID 19351156 DOI: 10.1021/Ja900852K  0.8
2009 Kodadek T. Emerging Investigators 2009 Molecular Biosystems. 5: 895. DOI: 10.1039/b912394f  0.8
2009 Kodadek T, Thomas S, Smith M, Sear K. Molecular BioSystems enters its fifth year! Molecular Biosystems. 5: 13-15. DOI: 10.1039/b819258h  0.8
2009 Nalley K, Johnston SA, Kodadek T. Nalley et al. reply Nature. 461: E8. DOI: 10.1038/Nature08407  0.8
2008 Kwon YU, Kodadek T. Encoded combinatorial libraries for the construction of cyclic peptoid microarrays Chemical Communications. 5704-5706. PMID 19009054 DOI: 10.1039/B812735B  0.8
2008 Ferdous A, O'Neal M, Nalley K, Sikder D, Kodadek T, Johnston SA. Phosphorylation of the Gal4 DNA-binding domain is essential for activator mono-ubiquitylation and efficient promoter occupancy Molecular Biosystems. 4: 1116-1125. PMID 18931787 DOI: 10.1039/B809291E  0.8
2008 Udugamasooriya DG, Dunham G, Ritchie C, Brekken RA, Kodadek T. The pharmacophore of a peptoid VEGF receptor 2 antagonist includes both side chain and main chain residues Bioorganic and Medicinal Chemistry Letters. 18: 5892-5894. PMID 18653335 DOI: 10.1016/J.Bmcl.2008.07.023  0.8
2008 Kodadek T. Proteomes take the electrophilic bait Nature Chemical Biology. 4: 387-388. PMID 18560426 DOI: 10.1038/Nchembio0708-387  0.8
2008 Kodadek T. Biochemistry: Molecular cloaking devices Nature. 453: 861-862. PMID 18548057 DOI: 10.1038/453861A  0.8
2008 Archer CT, Burdine L, Liu B, Ferdous A, Johnston SA, Kodadek T. Physical and functional interactions of monoubiquitylated transactivators with the proteasome. The Journal of Biological Chemistry. 283: 21789-98. PMID 18515799 DOI: 10.1074/Jbc.M803075200  0.8
2008 Udugamasooriya DG, Ritchie C, Brekken RA, Kodadek T. A peptoid antagonist of VEGF Receptor 2 recognizes a 'hotspot' in the extracellular domain distinct from the hormone-binding site Bioorganic and Medicinal Chemistry. 16: 6338-6343. PMID 18501615 DOI: 10.1016/J.Bmc.2008.05.015  0.8
2008 Kodadek T. Emerging investigators issue Molecular Biosystems. 4: 465. PMID 18493638 DOI: 10.1039/b806354k  0.8
2008 Tan NC, Yu P, Kwon YU, Kodadek T. High-throughput evaluation of relative cell permeability between peptoids and peptides Bioorganic and Medicinal Chemistry. 16: 5853-5861. PMID 18490170 DOI: 10.1016/J.Bmc.2008.04.074  0.8
2008 Udugamasooriya DG, Dineen SP, Brekken RA, Kodadek T. A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity Journal of the American Chemical Society. 130: 5744-5752. PMID 18386897 DOI: 10.1021/Ja711193X  0.8
2008 Shores KS, Udugamasooriya DG, Kodadek T, Knapp DR. Use of peptide analogue diversity library beads for increased depth of proteomic analysis: Application to cerebrospinal fluid Journal of Proteome Research. 7: 1922-1931. PMID 18357977 DOI: 10.1021/Pr7006889  0.8
2008 Marthandan N, Klyza S, Li S, Kwon YU, Kodadek T, Garner HR. Construction and evaluation of an automated light directed protein-detecting microarray synthesizer Ieee Transactions On Nanobioscience. 7: 20-27. PMID 18334452 DOI: 10.1109/Tnb.2008.2000146  0.8
2008 Archer CT, Delahodde A, Gonzalez F, Johnston SA, Kodadek T. Activation domain-dependent monoubiquitylation of Gal4 protein is essential for promoter binding in vivo. The Journal of Biological Chemistry. 283: 12614-23. PMID 18326036 DOI: 10.1074/Jbc.M801050200  0.8
2008 Lim HS, Archer CT, Kim YC, Hutchens T, Kodadek T. Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle. Chemical Communications (Cambridge, England). 1064-6. PMID 18292891 DOI: 10.1039/B717861A  0.8
2008 Hanaoka K, Lubag AJ, Castillo-Muzquiz A, Kodadek T, Sherry AD. The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain. Magnetic Resonance Imaging. 26: 608-17. PMID 18234462 DOI: 10.1016/J.Mri.2007.11.002  0.8
2008 Lee J, Yu P, Xiao X, Kodadek T. A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead". Molecular Biosystems. 4: 59-65. PMID 18075676 DOI: 10.1039/B712307H  0.8
2008 Kodadek T. Rise of the machines: Bruce Alberts and the biochemistry of multi-protein complexes Molecular Biosystems. 4: 1043-1045. DOI: 10.1039/B815439B  0.8
2008 Astle JM, Udugamasooriya DG, Smallshaw JE, Kodadek T. A VEGFR2 antagonist and other peptoids evade immune recognition International Journal of Peptide Research and Therapeutics. 14: 223-227. DOI: 10.1007/S10989-008-9136-1  0.8
2008 Astle JM, Kodadek T. Microarray Approaches to Autoantibody Profiling Clinical Proteomics: From Diagnosis to Therapy. 511-532. DOI: 10.1002/9783527622153.ch28  0.8
2007 Astle J, Ferguson JT, German JB, Harrigan GG, Kelleher NL, Kodadek T, Parks BA, Roth MJ, Singletary KW, Wenger CD, Mahady GB. Characterization of proteomic and metabolomic responses to dietary factors and supplements. The Journal of Nutrition. 137: 2787-93. PMID 18029500 DOI: 10.1093/Jn/137.12.2787  0.8
2007 Sikder D, Kodadek T. The neurohormone orexin stimulates hypoxia-inducible factor-1 activity Genes and Development. 21: 2995-3005. PMID 18006690 DOI: 10.1101/Gad.1584307  0.8
2007 Lim HS, Cai D, Archer CT, Kodadek T. Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle Journal of the American Chemical Society. 129: 12936-12937. PMID 17929816 DOI: 10.1021/Ja075469+  0.8
2007 Yu P, Kodadek T. Dynamics of the hypoxia-inducible factor-1-vascular endothelial growth factor promoter complex Journal of Biological Chemistry. 282: 35035-35045. PMID 17916562 DOI: 10.1074/Jbc.M707557200  0.8
2007 Liu B, Archer CT, Burdine L, Gillette TG, Kodadek T. Label transfer chemistry for the characterization of protein-protein interactions Journal of the American Chemical Society. 129: 12348-12349. PMID 17894490 DOI: 10.1021/Ja072904R  0.8
2007 Kwon YU, Kodadek T. Quantitative Comparison of the Relative Cell Permeability of Cyclic and Linear Peptides Chemistry and Biology. 14: 671-677. PMID 17584614 DOI: 10.1016/J.Chembiol.2007.05.006  0.8
2007 Lim HS, Archer CT, Kodadek T. Identification of a peptoid inhibitor of the proteasome 19S regulatory particle Journal of the American Chemical Society. 129: 7750-7751. PMID 17536803 DOI: 10.1021/Ja072027P  0.8
2007 Xiao X, Yu P, Lim HS, Sikder D, Kodadek T. Design and synthesis of a cell-permeable synthetic transcription factor mimic Journal of Combinatorial Chemistry. 9: 592-600. PMID 17530904 DOI: 10.1021/Cc070023A  0.8
2007 Yu P, Liu B, Kodadek T. A convenient, high-throughput assay for measuring the relative cell permeability of synthetic compounds Nature Protocols. 2: 23-30. PMID 17401333 DOI: 10.1038/Nprot.2007.1  0.8
2007 Xiao X, Yu P, Lim HS, Sikder D, Kodadek T. A cell-permeable synthetic transcription factor mimic Angewandte Chemie - International Edition. 46: 2865-2868. PMID 17351994 DOI: 10.1002/Anie.200604485  0.8
2007 Kwon YU, Kodadek T. Quantitative evaluation of the relative cell permeability of peptoids and peptides Journal of the American Chemical Society. 129: 1508-1509. PMID 17283989 DOI: 10.1021/Ja0668623  0.8
2007 Ferdous A, Sikder D, Gillette T, Nalley K, Kodadek T, Johnston SA. The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters Genes and Development. 21: 112-123. PMID 17167105 DOI: 10.1101/Gad.1493207  0.8
2007 Kodadek T, Thomas S, Smith M, Sear K. Molecular BioSystems spins out into 2008 Molecular Biosystems. 4: 10-12. DOI: 10.1039/b717515a  0.8
2006 Page TJ, Sikder D, Yang L, Pluta L, Wolfinger RD, Kodadek T, Thomas RS. Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival. Molecular Biosystems. 2: 627-39. PMID 17216044 DOI: 10.1039/B606129J  0.8
2006 Kodadek T, Michnick S. Introduction to monitoring and manipulating signaling networks Molecular Biosystems. 2: 603-604. PMID 17216040 DOI: 10.1039/B615197N  0.8
2006 Alluri P, Liu B, Yu P, Xiao X, Kodadek T. Isolation and characterization of coactivator-binding peptoids from a combinatorial library Molecular Biosystems. 2: 568-579. PMID 17216038 DOI: 10.1039/B608924K  0.8
2005 Liu B, Yu P, Alluri PG, Kodadek T. Simple reporter gene-based assays for hairpin poly(amide) conjugate permeability and DNA-binding activity in living cells Molecular Biosystems. 1: 307-317. PMID 16880996 DOI: 10.1039/B511514K  0.8
2005 Kreishman-Deitrick M, Goley ED, Burdine L, Denison C, Egile C, Li R, Murali N, Kodadek TJ, Welch MD, Rosen MK. NMR analyses of the activation of the Arp2/3 complex by neuronal Wiskott-Aldrich syndrome protein. Biochemistry. 44: 15247-56. PMID 16285728 DOI: 10.1021/Bi051065N  0.8
2005 Liu B, Alluri PG, Yu P, Kodadek T. A potent transactivation domain mimic with activity in living cells Journal of the American Chemical Society. 127: 8254-8255. PMID 15941237 DOI: 10.1021/Ja0515295  0.8
2005 Lin HJ, Kodadek T. Photo-induced oxidative cross-linking as a method to evaluate the specificity of protein-ligand interactions Journal of Peptide Research. 65: 221-228. PMID 15705166 DOI: 10.1111/J.1399-3011.2005.00227.X  0.8
2005 Li S, Marthandan N, Bowerman D, Garner HR, Kodadek T. Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy. Chemical Communications (Cambridge, England). 581-3. PMID 15672142 DOI: 10.1039/B415578E  0.8
2004 Kodadek T, Reddy MM, Olivos HJ, Bachhawat-Sikder K, Alluri PG. Synthetic molecules as antibody replacements Accounts of Chemical Research. 37: 711-718. PMID 15379586 DOI: 10.1021/Ar030145L  0.8
2004 Denison C, Kodadek T. Toward a general chemical method for rapidly mapping multi-protein complexes. Journal of Proteome Research. 3: 417-25. PMID 15253422 DOI: 10.1021/Pr034071J  0.8
2004 Li S, Bowerman D, Marthandan N, Klyza S, Luebke KJ, Garner HR, Kodadek T. Photolithographic synthesis of peptoids. Journal of the American Chemical Society. 126: 4088-9. PMID 15053581 DOI: 10.1021/Ja039565W  0.8
2003 Amini F, Denison C, Lin HJ, Kuo L, Kodadek T. Using oxidative crosslinking and proximity labeling to quantitatively characterize protein-protein and protein-Peptide complexes. Chemistry & Biology. 10: 1115-27. PMID 14652079 DOI: 10.1016/J.Chembiol.2003.11.001  0.8
2003 Alluri PG, Reddy MM, Bachhawat-Sikder K, Olivos HJ, Kodadek T. Isolation of Protein Ligands from Large Peptoid Libraries Journal of the American Chemical Society. 125: 13995-14004. PMID 14611236 DOI: 10.1021/Ja036417X  0.8
2003 Liu B, Han Y, Ferdous A, Corey DR, Kodadek T. Transcription activation by a PNA-peptide chimera in a mammalian cell extract. Chemistry & Biology. 10: 909-16. PMID 14583257 DOI: 10.1016/J.Chembiol.2003.09.008  0.8
2002 Liu B, Han Y, Corey DR, Kodadek T. Toward synthetic transcription activators: recruitment of transcription factors to DNA by a PNA-peptide chimera. Journal of the American Chemical Society. 124: 1838-9. PMID 11866581 DOI: 10.1021/Ja0164226  0.8
2002 Olivos HJ, Alluri PG, Reddy MM, Salony D, Kodadek T. Microwave-assisted solid-phase synthesis of peptoids Organic Letters. 4: 4057-4058. DOI: 10.1021/Ol0267578  0.8
2001 Zhang Z, Ly T, Kodadek T. An inhibitor of sequence-specific proteolysis that targets the substrate rather than the enzyme Chemistry and Biology. 8: 391-397. PMID 11325594 DOI: 10.1016/S1074-5521(01)00021-7  0.8
2000 Fancy DA, Denison C, Kim K, Xie Y, Holdeman T, Amini F, Kodadek T. Scope, limitations and mechanistic aspects of the photo-induced cross-linking of proteins by water-soluble metal complexes. Chemistry & Biology. 7: 697-708. PMID 10980450 DOI: 10.1016/S1074-5521(00)00020-X  0.8
2000 Xie Y, Denison C, Yang SH, Fancy DA, Kodadek T. Biochemical characterization of the TATA-binding protein-Gal4 activation domain complex. The Journal of Biological Chemistry. 275: 31914-20. PMID 10931832 DOI: 10.1074/Jbc.M003760200  0.8
2000 Zhang Z, Zhu W, Kodadek T. Selection and application of peptide-binding peptides. Nature Biotechnology. 18: 71-4. PMID 10625395 DOI: 10.1038/71951  0.32
1999 Patikoglou GA, Kim JL, Sun L, Yang SH, Kodadek T, Burley SK. TATA element recognition by the TATA box-binding protein has been conserved throughout evolution. Genes & Development. 13: 3217-30. PMID 10617571 DOI: 10.1101/Gad.13.24.3217  0.8
1998 Campbell LA, Kodadek T, Brown KC. Protein cross-linking mediated by metalloporphyrins Bioorganic and Medicinal Chemistry. 6: 1301-1307. PMID 9784871 DOI: 10.1016/S0968-0896(98)00120-5  0.8
1998 Denison C, Kodadek T. Small-molecule-based strategies for controlling gene expression. Chemistry & Biology. 5: R129-45. PMID 9653545 DOI: 10.1016/S1074-5521(98)90167-3  0.8
1998 Kodadek T. Mechanistic parallels between DNA replication, recombination and transcription. Trends in Biochemical Sciences. 23: 79-83. PMID 9538694 DOI: 10.1016/S0968-0004(97)01165-1  0.36
1997 Jiang H, Salinas F, Kodadek T. The gene 32 single-stranded DNA-binding protein is not bound stably to the phage T4 presynaptic filament. Biochemical and Biophysical Research Communications. 231: 600-5. PMID 9070854 DOI: 10.1006/Bbrc.1997.6160  0.4
1997 Jiang H, Xie Y, Houston P, Stemke-Hale K, Mortensen UH, Rothstein R, Kodadek T. Direct association between the yeast Rad51 and Rad54 recombination proteins. The Journal of Biological Chemistry. 271: 33181-6. PMID 8969173 DOI: 10.1074/Jbc.271.52.33181  0.32
1997 Barry JF, Campbell L, Smith DW, Kodadek T. Synthesis and catalytic epoxidation activity of terpene-derived D4-symmetric metalloporphyrins Tetrahedron. 53: 7753-7776. DOI: 10.1016/S0040-4020(97)00470-5  0.8
1996 Campbell LA, Kodadek T. Enantioselective catalysis of epoxidation by metalloporphyrins: Application to enantioselective synthesis Journal of Molecular Catalysis a: Chemical. 113: 293-310. DOI: 10.1016/S1381-1169(96)00164-1  0.8
1995 Sessler JL, Lisowski J, Boudreaux KA, Lynch V, Barry J, Kodadek TJ. Synthesis and characterization of Diaryl Sapphyrins prepared under Lindsey-type conditions Journal of Organic Chemistry. 60: 5975-5978.  0.8
1994 Houston P, Kodadek T. Spectrophotometric assay for enzyme-mediated unwinding of double-stranded DNA Proceedings of the National Academy of Sciences of the United States of America. 91: 5471-5474. PMID 8202510 DOI: 10.1073/Pnas.91.12.5471  0.8
1992 Maxwell JL, Brown KC, Bartley DW, Kodadek T. Mechanism of the rhodium porphyrin-catalyzed cyclopropanation of alkenes. Science (New York, N.Y.). 256: 1544-7. PMID 17836323 DOI: 10.1126/Science.256.5063.1544  0.8
1992 Maine IP, Sun D, Hurley LH, Kodadek T. The antitumor agent CC-1065 inhibits helicase-catalyzed unwinding of duplex DNA. Biochemistry. 31: 3968-75. PMID 1314652 DOI: 10.1021/Bi00131A012  0.8
1991 O'Malley S, Kodadek T. Asymmetric Cyclopropanation of alkenes catalyzed by a "chiral wall" prophyrin Tetrahedron Letters. 32: 2445-2448. DOI: 10.1016/S0040-4039(00)74349-8  0.8
1990 Bartley DW, Kodadek TJ. Catalysis of Diels-Alder reactions by metalloporphyrins Tetrahedron Letters. 31: 6303-6306. DOI: 10.1016/S0040-4039(00)97048-5  0.8
1987 Kodadek T, Alberts BM. Stimulation of protein-directed strand exchange by a DNA helicase. Nature. 326: 312-4. PMID 2950327 DOI: 10.1038/326312A0  0.64
1986 Collman JP, Kodadek T, Brauman JI. Oxygenation of styrene by cytochrome P-450 model systems: A mechanistic study Journal of the American Chemical Society®. 108: 2588-2594. DOI: 10.1002/Chin.198637118  0.8
1986 COLLMAN JP, KODADEK T, BRAUMAN JI. ChemInform Abstract: Oxygenation of Styrene by Cytochrome P-450 Model Systems: A Mechanistic Study. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198637118  0.8
1985 Collman JP, Brauman JI, Meunier B, Hayashi T, Kodadek T, Raybuck SA. Epoxidation of olefins by cytochrome P-450 model compounds: kinetics and stereochemistry of oxygen atom transfer and origin of shape selectivity Journal of the American Chemical Society. 107: 2000-2005. DOI: 10.1021/Ja00293A034  0.8
1985 COLLMAN JP, KODADEK T, RAYBUCK SA, BRAUMAN JI, PAPAZIAN LM. ChemInform Abstract: Mechanism of Oxygen Atom Transfer from High Valent Iron Porphyrins to Olefins: Implications to the Biological Epoxidation of Olefins by Cytochrome P-450. Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198544103  0.8
1985 Kodadek T, Raybuck SA, Collman JP, Brauman JI, Papazian LM. Mechanism of oxygen atom transfer from high valent iron porphyrins to olefins: implications to the biological epoxidation of olefins by cytochrome P-450 Journal of the American Chemical Society. 107: 4343-4345. DOI: 10.1002/Chin.198544103  0.8
1984 Collman JP, Brauman JI, Meunier B, Raybuck SA, Kodadek T. Epoxidation of olefins by cytochrome P-450 model compounds: mechanism of oxygen atom transfer. Proceedings of the National Academy of Sciences of the United States of America. 81: 3245-8. PMID 6587349 DOI: 10.1073/Pnas.81.10.3245  0.8
1983 Collman JP, Kodadek T, Raybuck SA, Meunier B. Oxygenation of hydrocarbons by cytochrome P-450 model compounds: modification of reactivity by axial ligands. Proceedings of the National Academy of Sciences of the United States of America. 80: 7039-41. PMID 6580626 DOI: 10.1073/Pnas.80.22.7039  0.8
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