Patrick Holt - Publications

Affiliations: 
Chemistry Bellarmine University 

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lauzon-Joset JF, Mincham KT, Scott NM, Khandan Y, Stumbles PA, Holt PG, Strickland DH. Protection against neonatal respiratory viral infection via maternal treatment during pregnancy with the benign immune training agent OM-85. Clinical & Translational Immunology. 10: e1303. PMID 34249358 DOI: 10.1002/cti2.1303  0.01
2021 Holt P, Strickland D. Innate Immune Training for prevention of recurrent wheeze in early childhood. American Journal of Respiratory and Critical Care Medicine. PMID 33844949 DOI: 10.1164/rccm.202103-0698ED  0.08
2021 Tang HHF, Teo SM, Sly PD, Holt PG, Inouye M. The intersect of genetics, environment, and microbiota in asthma-perspectives and challenges. The Journal of Allergy and Clinical Immunology. 147: 781-793. PMID 33678251 DOI: 10.1016/j.jaci.2020.08.026  0.01
2021 Lingham G, Mackey DA, Zhu K, Lucas RM, Black LJ, Oddy WH, Holt P, Walsh JP, Sanfilippo PG, Chan She Ping-Delfos W, Yazar S. Time spent outdoors through childhood and adolescence - assessed by 25-hydroxyvitamin D concentration - and risk of myopia at 20 years. Acta Ophthalmologica. PMID 33423400 DOI: 10.1111/aos.14709  0.01
2020 Mincham KT, Jones AC, Bodinier M, Scott NM, Lauzon-Joset JF, Stumbles PA, Bosco A, Holt PG, Strickland DH. Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming. Frontiers in Immunology. 11: 601494. PMID 33424847 DOI: 10.3389/fimmu.2020.601494  0.01
2020 Choi T, Devries M, Bacharier L, Busse W, Camargo CA, Cohen R, Demuri GP, Evans MD, Fitzpatrick AM, Gergen PJ, Grindle K, Gruchalla R, Hartert T, Hasegawa K, Khurana Hershey GK, ... Holt P, et al. Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection. American Journal of Respiratory and Critical Care Medicine. PMID 33357024 DOI: 10.1164/rccm.202010-3753OC  0.01
2020 Perez Chacon G, Estcourt MJ, Totterdell J, Campbell DE, Perrett KP, Marsh JA, Richmond PC, Wood N, Gold MS, Holt PG, Waddington CS, Snelling TL. OPTIMUM study protocol: an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule. Bmj Open. 10: e042838. PMID 33334840 DOI: 10.1136/bmjopen-2020-042838  0.01
2020 Tang HHF, Lang A, Teo SM, Judd LM, Gangnon R, Evans MD, Lee KE, Vrtis R, Holt PG, Lemanske RF, Jackson DJ, Holt KE, Inouye M, Gern JE. Developmental patterns in the nasopharyngeal microbiome during infancy are associated with asthma risk. The Journal of Allergy and Clinical Immunology. PMID 33091409 DOI: 10.1016/j.jaci.2020.10.009  0.01
2020 Vogelezang S, Bradfield JP, Ahluwalia TS, Curtin JA, Lakka TA, Grarup N, Scholz M, van der Most PJ, Monnereau C, Stergiakouli E, Heiskala A, Horikoshi M, Fedko IO, Vilor-Tejedor N, Cousminer DL, ... ... Holt PG, et al. Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. Plos Genetics. 16: e1008718. PMID 33045005 DOI: 10.1371/journal.pgen.1008718  0.01
2020 Brunwasser SM, Snyder BM, Driscoll AJ, Fell DB, Savitz DA, Feikin DR, Skidmore B, Bhat N, Bont LJ, Dupont WD, Wu P, Gebretsadik T, Holt PG, Zar HJ, Ortiz JR, et al. Assessing the strength of evidence for a causal effect of respiratory syncytial virus lower respiratory tract infections on subsequent wheezing illness: a systematic review and meta-analysis. The Lancet. Respiratory Medicine. 8: 795-806. PMID 32763206 DOI: 10.1016/S2213-2600(20)30109-0  0.01
2020 Huang QQ, Tang HHF, Teo SM, Mok D, Ritchie SC, Nath AP, Brozynska M, Salim A, Bakshi A, Holt BJ, Khor CC, Sly PD, Holt PG, Holt KE, Inouye M. Neonatal genetics of gene expression reveal potential origins of autoimmune and allergic disease risk. Nature Communications. 11: 3761. PMID 32724101 DOI: 10.1038/s41467-020-17477-x  0.01
2020 Holt P, Strickland D, Custovic A. Targeting maternal immune function during pregnancy for asthma prevention in offspring: harnessing the "farm effect"? The Journal of Allergy and Clinical Immunology. PMID 32333916 DOI: 10.1016/j.jaci.2020.04.008  0.01
2020 Jones AC, Anderson D, Troy NM, Mallon D, Hartmann R, Serralha M, Holt B, Bosco A, Holt PG. Rewiring of gene networks underlying mite allergen-induced CD4+Th-cell responses during immunotherapy. Allergy. PMID 32181882 DOI: 10.1111/all.14265  0.01
2019 Mincham KT, Leffler J, Scott NM, Lauzon-Joset JF, Stumbles PA, Holt PG, Strickland DH. Quantification of serum ovalbumin-specific immunoglobulin E titrevia passive cutaneous anaphylaxis assay. Bio-Protocol. 9: e3184. PMID 33654986 DOI: 10.21769/BioProtoc.3184  0.01
2019 Mincham KT, Scott NM, Lauzon-Joset JF, Leffler J, Stumbles PA, Holt PG, Strickland DH. Early life ovalbumin sensitization and aerosol challenge for the induction ofallergic airway inflammation in a BALB/c murine model. Bio-Protocol. 9: e3181. PMID 33654984 DOI: 10.21769/BioProtoc.3181  0.01
2019 Estcourt MJ, Campbell DE, Gold MS, Richmond P, Allen KJ, Quinn HE, Marsh JA, Peters RL, Valerio C, Dai D, Waddington CS, Wood NJ, McIntyre PB, Holt PG, Snelling TL. Whole cell pertussis vaccination and decreased risk of IgE-mediated food allergy: a nested case-control study. The Journal of Allergy and Clinical Immunology. in Practice. PMID 31891824 DOI: 10.1016/j.jaip.2019.12.020  0.01
2019 Thyssen JP, Ahluwalia TS, Paternoster L, Ballardini N, Bergström A, Melén E, Chawes B, Stokholm J, Hourihane JO, O'Sullivan DM, Bager P, Maelbye M, Bustamante M, Torrent M, Esplugues A, ... ... Holt PG, et al. Interaction between filaggrin mutations and neonatal cat exposure in atopic dermatitis. Allergy. PMID 31877228 DOI: 10.1111/All.14162  0.01
2019 Lauzon-Joset JF, Mincham KT, Abad AP, Short BP, Holt PG, Strickland DH, Leffler J. Estrogen amplifies pre-existing atopy-associated Th2-bias in an experimental asthma model. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 31785105 DOI: 10.1111/cea.13544  0.01
2019 Bedke N, Swindle EJ, Molnar C, Holt PG, Strickland DH, Roberts GC, Morris R, Holgate ST, Davies DE, Blume C. A method for the generation of large numbers of dendritic cells from CD34+ hematopoietic stem cells from cord blood. Journal of Immunological Methods. 112703. PMID 31711888 DOI: 10.1016/j.jim.2019.112703  0.01
2019 Tang HHF, Sly PD, Holt PG, Holt KE, Inouye M. Systems biology and big data in asthma and allergy - recent discoveries and emerging challenges. The European Respiratory Journal. PMID 31619470 DOI: 10.1183/13993003.00844-2019  0.01
2019 Jones AC, Anderson D, Galbraith S, Fantino E, Cardenas DG, Read JF, Serralha M, Holt BJ, Strickland DH, Sly PD, Bosco A, Holt PG. Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles. The Journal of Allergy and Clinical Immunology. PMID 31437489 DOI: 10.1016/j.jaci.2019.07.043  0.01
2019 Guo J, Zhu W, Wang H, Holt PG, Zhang G, Liu C. Risk factors and prognosis of recurrent wheezing in Chinese young children: a prospective cohort study. Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. 15: 38. PMID 31244890 DOI: 10.1186/s13223-019-0351-4  0.04
2019 Sly PD, Galbraith S, Islam Z, Holt B, Troy N, Holt PG. Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM85. The Journal of Allergy and Clinical Immunology. PMID 31185221 DOI: 10.1016/j.jaci.2019.05.032  0.01
2019 Leffler J, Read JF, Jones AC, Mok D, Hollams EM, Laing IA, Le Souef PN, Sly PD, Kusel MMH, de Klerk NH, Bosco A, Holt PG, Strickland DH. Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology. PMID 30985951 DOI: 10.1111/pai.13063  0.01
2019 Zhu K, Oddy WH, Holt P, Ping-Delfos WCS, McVeigh J, Straker L, Mori TA, Lye S, Pennell C, Walsh JP. Relationship Between Vitamin D Status From Childhood to Early Adulthood With Body Composition in Young Australian Adults. Journal of the Endocrine Society. 3: 563-576. PMID 30805568 DOI: 10.1210/Js.2018-00349  0.01
2018 Lauzon-Joset JF, Scott NM, Mincham KT, Stumbles PA, Holt PG, Strickland DH. Pregnancy induces a steady-state shift in alveolar macrophage M1/M2 phenotype that is associated with a heightened severity of Influenza infection: mechanistic insight using mouse models. The Journal of Infectious Diseases. PMID 30576502 DOI: 10.1093/infdis/jiy732  0.01
2018 Jones AC, Anderson D, Galbraith S, Fantino E, Gutierrez Cardenas D, Read JF, Serralha M, Holt BJ, Strickland DH, Sly PD, Bosco A, Holt PG. Personalised Transcriptomics Reveals Heterogeneous Immunophenotypes in Children with Viral Bronchiolitis. American Journal of Respiratory and Critical Care Medicine. PMID 30562046 DOI: 10.1164/rccm.201804-0715OC  0.01
2018 Tang HH, Teo SM, Belgrave DC, Evans MD, Jackson DJ, Brozynska M, Kusel MM, Johnston SL, Gern JE, Lemanske RF, Simpson A, Custovic A, Sly PD, Holt PG, Holt KE, et al. Trajectories of childhood immune development and respiratory health relevant to asthma and allergy. Elife. 7. PMID 30320550 DOI: 10.7554/eLife.35856  0.01
2018 Holt PG, Mok D, Panda D, Renn L, Fabozzi G, deKlerk NH, Kusel MM, Serralha M, Hollams EM, Holt BJ, Sly PD, Rabin RL. Developmental regulation of type 1 and type 3 IFN production and risk for infant infections and asthma development. The Journal of Allergy and Clinical Immunology. PMID 30217468 DOI: 10.1016/J.Jaci.2018.08.035  0.01
2018 Teo SM, Tang HHF, Mok D, Judd LM, Watts SC, Pham K, Holt BJ, Kusel M, Serralha M, Troy N, Bochkov YA, Grindle K, Lemanske RF, Johnston SL, Gern JE, ... ... Holt PG, et al. Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease. Cell Host & Microbe. 24: 341-352.e5. PMID 30212648 DOI: 10.1016/j.chom.2018.08.005  0.01
2018 Sly PD, Holt PG. Predicting steroid responsiveness in asthmatic children: are we there yet? The Journal of Allergy and Clinical Immunology. PMID 30170127 DOI: 10.1016/j.jaci.2018.07.035  0.01
2018 Mincham KT, Scott NM, Lauzon-Joset JF, Leffler J, Larcombe AN, Stumbles PA, Robertson SA, Pasquali C, Holt PG, Strickland DH. Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation. The Journal of Clinical Investigation. PMID 30153109 DOI: 10.1172/JCI122631  0.01
2018 Lauzon-Joset JF, Jones AC, Mincham KT, Thomas JA, Rosenthal LA, Bosco A, Holt PG, Strickland DH. Atopy-Dependent and Independent Immune Responses in the Heightened Severity of Atopics to Respiratory Viral Infections: Rat Model Studies. Frontiers in Immunology. 9: 1805. PMID 30150981 DOI: 10.3389/fimmu.2018.01805  0.01
2018 Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, ... ... Holt P, et al. Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nature Genetics. PMID 30116036 DOI: 10.1038/S41588-018-0197-6  0.01
2018 Leffler J, Jones AC, Hollams EM, Prastanti F, Le Souëf PN, Holt PG, Bosco A, Laing IA, Strickland DH. Basophil levels in PBMC population during childhood acute wheeze/asthma are associated with future exacerbations. The Journal of Allergy and Clinical Immunology. PMID 30036597 DOI: 10.1016/j.jaci.2018.07.003  0.01
2018 Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, ... ... Holt P, et al. Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nature Genetics. PMID 30013184 DOI: 10.1038/S41588-018-0157-1  0.01
2018 Saiganesh A, Hales BJ, Li Y, Holt PG, Le Souëf PN, Zhang G. A marked shift in innate and adaptive immune response in chinese immigrants living in a western environment. Allergy. PMID 29935021 DOI: 10.1111/all.13531  0.01
2018 Sly PD, Holt PG. Pollution, climate change, and childhood asthma in Australia. The Medical Journal of Australia. 208: 297-298. PMID 29642815 DOI: 10.5694/mja17.01145  0.01
2018 Jones AC, Troy NM, White E, Hollams EM, Gout AM, Ling KM, Kicic A, Stick SM, Sly PD, Holt PG, Hall GL, Bosco A. Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics. Scientific Reports. 8: 1511. PMID 29367592 DOI: 10.1038/s41598-018-19837-6  0.01
2018 Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, ... ... Holt P, et al. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nature Genetics. 50: 42-53. PMID 29273806 DOI: 10.1038/S41588-017-0014-7  0.01
2017 Leffler J, Mincham KT, Mok D, Blank F, Holt PG, Stumbles PA, Strickland DH. Functional differences in airway dendritic cells determine susceptibility to IgE-sensitisation. Immunology and Cell Biology. PMID 29363184 DOI: 10.1111/imcb.12005  0.01
2017 Brealey JC, Chappell KJ, Galbraith S, Fantino E, Gaydon J, Tozer S, Young PR, Holt PG, Sly PD. Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children. Respirology (Carlton, Vic.). PMID 28913912 DOI: 10.1111/Resp.13179  0.01
2017 Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, et al. After asthma: redefining airways diseases. Lancet (London, England). PMID 28911920 DOI: 10.1016/S0140-6736(17)30879-6  0.01
2017 Renz H, Holt PG, Inouye M, Logan AC, Prescott SL, Sly PD. An exposome perspective: Early-life events and immune development in a changing world. The Journal of Allergy and Clinical Immunology. 140: 24-40. PMID 28673401 DOI: 10.1016/j.jaci.2017.05.015  0.01
2017 Zhu K, Oddy WH, Holt P, Ping-Delfos WCS, Mountain J, Lye S, Pennell C, Hart PH, Walsh JP. Tracking of vitamin D status from childhood to early adulthood and its association with peak bone mass. The American Journal of Clinical Nutrition. PMID 28592609 DOI: 10.3945/Ajcn.116.150524  0.01
2017 Tyser AR, Holt PA, Lor Randall R. Diagnostic Evaluation of Upper Extremity Masses and Tumors. Orthopedics. 1-7. PMID 28530767 DOI: 10.3928/01477447-20170518-02  0.01
2017 Tarique AA, Sly PD, Holt PG, Bosco A, Ware RS, Logan J, Bell SC, Wainwright CE, Fantino E. CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 28428011 DOI: 10.1016/j.jcf.2017.03.011  0.01
2016 White EC, de Klerk N, Hantos Z, Priston M, Hollams EM, James A, Sly PD, Holt PG, Hall GL. Mannitol challenge testing for asthma in a community cohort of young adults. Respirology (Carlton, Vic.). PMID 27917572 DOI: 10.1111/resp.12955  0.01
2016 Francis JP, Richmond PC, Strickland D, Prescott SL, Pomat WS, Michael A, Nadal-Sims MA, Edwards-Devitt CJ, Holt PG, Lehmann D, van den Biggelaar AH. Cord blood Streptococcus pneumoniae specific cellular immune responses predict early pneumococcal carriage in high-risk infants in Papua New Guinea. Clinical and Experimental Immunology. PMID 27859014 DOI: 10.1111/cei.12902  0.01
2016 von Garnier C, Blank F, Rothen-Rutishauser B, Goethert JR, Holt PG, Stumbles PA, Strickland DH. Identification and Characterization of a Dendritic Cell Precursor in Parenchymal Lung Tissue. American Journal of Respiratory Cell and Molecular Biology. PMID 27779901 DOI: 10.1165/rcmb.2016-0058OC  0.01
2016 Hollams EM, Teo SM, Kusel M, Holt BJ, Holt KE, Inouye M, De Klerk NH, Zhang G, Sly PD, Hart PH, Holt PG. Vitamin D over the first decade and susceptibility to childhood allergy and asthma. The Journal of Allergy and Clinical Immunology. PMID 27726947 DOI: 10.1016/j.jaci.2016.07.032  0.01
2016 Sly PD, Varghese J, Noor F, Tang ML, Laing I, Oo S, Prastanti F, LeSouef PN, Holt PG. Severe winter asthma exacerbations may be prevented by omalizumab but no carry over effect. The Journal of Allergy and Clinical Immunology. PMID 27637383 DOI: 10.1016/j.jaci.2016.07.035  0.01
2016 Holt PG, Snelling T, White OJ, Sly PD, DeKlerk N, Carapetis J, Biggelaar AV, Wood N, McIntyre P, Gold M. Transiently increased IgE responses in infants and pre-schoolers receiving only acellular Diphtheria-Pertussis-Tetanus (DTaP) vaccines compared to those initially receiving at least one dose of cellular vaccine (DTwP) - Immunological curiosity or canary in the mine? Vaccine. PMID 27265452 DOI: 10.1016/j.vaccine.2016.05.048  1
2016 Black LJ, Burrows S, Lucas RM, Marshall CE, Huang RC, Chan She Ping-Delfos W, Beilin LJ, Holt PG, Hart PH, Oddy WH, Mori TA. Serum 25-hydroxyvitamin D concentrations and cardiometabolic risk factors in adolescents and young adults. The British Journal of Nutrition. 115: 1994-2002. PMID 27153206 DOI: 10.1017/S0007114516001185  1
2016 Troy NM, Hollams EM, Holt PG, Bosco A. Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses. Bmc Medical Genomics. 9: 9. PMID 26922672 DOI: 10.1186/s12920-016-0171-z  1
2016 Eguíluz-Gracia I, Bosco A, Dollner R, Melum GR, Lexberg MH, Jones AC, Dheyauldeen SA, Holt PG, Bækkevold ES, Jahnsen FL. Rapid recruitment of CD14(+) monocytes in experimentally induced allergic rhinitis in human subjects. The Journal of Allergy and Clinical Immunology. PMID 26851967 DOI: 10.1016/j.jaci.2015.11.025  0.01
2015 Holt PG, Sly PD. Environmental Microbial Exposure and Protection against Asthma. The New England Journal of Medicine. 373: 2576-8. PMID 26699175 DOI: 10.1056/NEJMcibr1511291  0.01
2015 Marenholz I, Esparza-Gordillo J, Rüschendorf F, Bauerfeind A, Strachan DP, Spycher BD, Baurecht H, Margaritte-Jeannin P, Sääf A, Kerkhof M, Ege M, Baltic S, Matheson MC, Li J, Michel S, ... ... Holt PG, et al. Meta-analysis identifies seven susceptibility loci involved in the atopic march. Nature Communications. 6: 8804. PMID 26542096 DOI: 10.1038/Ncomms9804  1
2015 Holt PG, Strickland D, Bosco A, Belgrave D, Hales B, Simpson A, Hollams E, Holt B, Kusel M, Ahlstedt S, Sly PD, Custovic A. Distinguishing benign from pathologic TH2 immunity in atopic children. The Journal of Allergy and Clinical Immunology. PMID 26518094 DOI: 10.1016/j.jaci.2015.08.044  1
2015 Holt PG. The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stage. The Journal of Allergy and Clinical Immunology. 136: 15-22. PMID 26145983 DOI: 10.1016/j.jaci.2015.05.011  0.01
2015 Tarique AA, Logan J, Thomas E, Holt PG, Sly PD, Fantino E. Phenotypic, Functional and Plasticity Features of Classical and Alternatively Activated Human Macrophages. American Journal of Respiratory Cell and Molecular Biology. PMID 25870903 DOI: 10.1165/rcmb.2015-0012OC  1
2015 Teo SM, Mok D, Pham K, Kusel M, Serralha M, Troy N, Holt BJ, Hales BJ, Walker ML, Hollams E, Bochkov YA, Grindle K, Johnston SL, Gern JE, Sly PD, ... Holt PG, et al. The infant nasopharyngeal microbiome impacts severity of lower respiratory infection and risk of asthma development. Cell Host & Microbe. 17: 704-15. PMID 25865368 DOI: 10.1016/j.chom.2015.03.008  1
2015 Hong X, Hao K, Ladd-Acosta C, Hansen KD, Tsai HJ, Liu X, Xu X, Thornton TA, Caruso D, Keet CA, Sun Y, Wang G, Luo W, Kumar R, Fuleihan R, ... ... Holt PG, et al. Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Nature Communications. 6: 6304. PMID 25710614 DOI: 10.1038/Ncomms7304  1
2015 Snyder RD, Holt PA, Maguire JM, Trent JO. Evidence for the contribution of non-covalent steroid interactions between DNA and topoisomerase in the genotoxicity of steroids. Drug and Chemical Toxicology. 38: 212-9. PMID 24975547 DOI: 10.3109/01480545.2014.928725  0.01
2014 Strickland DH, Fear V, Shenton S, Wikstrom ME, Zosky G, Larcombe AN, Holt PG, Berry C, von Garnier C, Stumbles PA. Persistent and compartmentalised disruption of dendritic cell subpopulations in the lung following influenza A virus infection. Plos One. 9: e111520. PMID 25398128 DOI: 10.1371/journal.pone.0111520  0.01
2014 Walker ML, Holt KE, Anderson GP, Teo SM, Sly PD, Holt PG, Inouye M. Elucidation of pathways driving asthma pathogenesis: development of a systems-level analytic strategy. Frontiers in Immunology. 5: 447. PMID 25295037 DOI: 10.3389/fimmu.2014.00447  1
2014 Zhang G, Lai CT, Hartmann P, Oddy WH, Kusel MM, Sly PD, Holt PG. Anti-infective proteins in breast milk and asthma-associated phenotypes during early childhood. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology. 25: 544-51. PMID 25224875 DOI: 10.1111/Pai.12265  1
2014 Black LJ, Burrows SA, Jacoby P, Oddy WH, Beilin LJ, Chan She Ping-Delfos W, Marshall CE, Holt PG, Hart PH, Mori TA. Vitamin D status and predictors of serum 25-hydroxyvitamin D concentrations in Western Australian adolescents. The British Journal of Nutrition. 112: 1154-62. PMID 25137493 DOI: 10.1017/S000711451400186X  0.01
2014 Hartwig IRV, Sly PD, Schmidt LA, Van Lieshout RJ, Bienenstock J, Holt PG, Arck PC. Prenatal adverse life events increase the risk for atopic diseases in children, which is enhanced in the absence of a maternal atopic predisposition Journal of Allergy and Clinical Immunology. 134: 160-169.e7. PMID 25117802 DOI: 10.1016/J.Jaci.2014.01.033  1
2014 Bousquet J, Gern JE, Martinez FD, Anto JM, Johnson CC, Holt PG, Lemanske RF, Le Souëf PN, Tepper RS, von Mutius ER, Arshad SH, Bacharier LB, Becker A, Belanger K, Bergström A, et al. Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop. The Journal of Allergy and Clinical Immunology. 133: 1535-46. PMID 24636091 DOI: 10.1016/J.Jaci.2014.01.018  1
2014 Black LJ, Jacoby P, She Ping-Delfos WC, Mori TA, Beilin LJ, Olynyk JK, Ayonrinde OT, Huang RC, Holt PG, Hart PH, Oddy WH, Adams LA. Low serum 25-hydroxyvitamin D concentrations associate with non-alcoholic fatty liver disease in adolescents independent of adiposity. Journal of Gastroenterology and Hepatology. 29: 1215-22. PMID 24611991 DOI: 10.1111/jgh.12541  1
2014 Zosky GR, Hart PH, Whitehouse AJ, Kusel MM, Ang W, Foong RE, Chen L, Holt PG, Sly PD, Hall GL. Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of age. Annals of the American Thoracic Society. 11: 571-7. PMID 24601713 DOI: 10.1513/AnnalsATS.201312-423OC  0.01
2014 Holt PG. Prevention--what is the most promising approach? Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology. 25: 12-4. PMID 24588480 DOI: 10.1111/pai.12194  0.01
2014 Holt PG, Strickland DH, Hales BJ, Sly PD. Defective respiratory tract immune surveillance in asthma: a primary causal factor in disease onset and progression. Chest. 145: 370-8. PMID 24493508 DOI: 10.1378/chest.13-1341  0.01
2014 Wood N, Marshall H, White OJ, Holt PG, McIntyre P. Antibody and cell-mediated immunity to pertussis 4 years after monovalent acellular pertussis vaccine at birth. The Pediatric Infectious Disease Journal. 33: 511-7. PMID 24445839 DOI: 10.1097/INF.0000000000000246  1
2014 Ferreira MA, Matheson MC, Tang CS, Granell R, Ang W, Hui J, Kiefer AK, Duffy DL, Baltic S, Danoy P, Bui M, Price L, Sly PD, Eriksson N, Madden PA, ... ... Holt PG, et al. Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. The Journal of Allergy and Clinical Immunology. 133: 1564-71. PMID 24388013 DOI: 10.1016/J.Jaci.2013.10.030  1
2014 Hollams EM, de Klerk NH, Holt PG, Sly PD. Persistent effects of maternal smoking during pregnancy on lung function and asthma in adolescents. American Journal of Respiratory and Critical Care Medicine. 189: 401-7. PMID 24251622 DOI: 10.1164/rccm.201302-0323OC  0.01
2013 Snyder RD, Holt PA, Maguire JM, Trent JO. Prediction of noncovalent Drug/DNA interaction using computational docking models: studies with over 1350 launched drugs. Environmental and Molecular Mutagenesis. 54: 668-81. PMID 23893771 DOI: 10.1002/em.21796  0.01
2013 Bønnelykke K, Matheson MC, Pers TH, Granell R, Strachan DP, Alves AC, Linneberg A, Curtin JA, Warrington NM, Standl M, Kerkhof M, Jonsdottir I, Bukvic BK, Kaakinen M, Sleimann P, ... ... Holt P, et al. Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Nature Genetics. 45: 902-6. PMID 23817571 DOI: 10.1038/Ng.2694  1
2013 Holt PG, Sly PD, Sampson HA, Robinson P, Loh R, Lowenstein H, Calatroni A, Sayre P. Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study. The Journal of Allergy and Clinical Immunology. 132: 991-3.e1. PMID 23768574 DOI: 10.1016/j.jaci.2013.04.049  0.01
2013 Blank F, Stumbles PA, Seydoux E, Holt PG, Fink A, Rothen-Rutishauser B, Strickland DH, von Garnier C. Size-dependent uptake of particles by pulmonary antigen-presenting cell populations and trafficking to regional lymph nodes. American Journal of Respiratory Cell and Molecular Biology. 49: 67-77. PMID 23492193 DOI: 10.1165/rcmb.2012-0387OC  0.01
2013 Pomat WS, van den Biggelaar AH, Phuanukoonnon S, Francis J, Jacoby P, Siba PM, Alpers MP, Reeder JC, Holt PG, Richmond PC, Lehmann D. Safety and immunogenicity of neonatal pneumococcal conjugate vaccination in Papua New Guinean children: a randomised controlled trial. Plos One. 8: e56698. PMID 23451070 DOI: 10.1371/journal.pone.0056698  1
2013 Whitehouse AJ, Holt BJ, Serralha M, Holt PG, Hart PH, Kusel MM. Maternal vitamin D levels and the autism phenotype among offspring. Journal of Autism and Developmental Disorders. 43: 1495-504. PMID 23070790 DOI: 10.1007/s10803-012-1676-8  1
2012 Le HT, Miller MC, Buscaglia R, Dean WL, Holt PA, Chaires JB, Trent JO. Not all G-quadruplexes are created equally: An investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4 Organic and Biomolecular Chemistry. 10: 9393-9404. PMID 23108607 DOI: 10.1039/c2ob26504d  1
2012 Rate A, Bosco A, McKenna KL, Holt PG, Upham JW. Airway epithelial cells condition dendritic cells to express multiple immune surveillance genes. Plos One. 7: e44941. PMID 22984588 DOI: 10.1371/journal.pone.0044941  0.01
2012 Lisciandro JG, Prescott SL, Nadal-Sims MG, Devitt CJ, Richmond PC, Pomat W, Siba PM, Holt PG, Strickland DH, van den Biggelaar AH. Neonatal antigen-presenting cells are functionally more quiescent in children born under traditional compared with modern environmental conditions. The Journal of Allergy and Clinical Immunology. 130: 1167-1174.e10. PMID 22818765 DOI: 10.1016/j.jaci.2012.06.005  0.01
2012 Lisciandro JG, Prescott SL, Nadal-Sims MG, Devitt CJ, Pomat W, Siba PM, Tulic MC, Holt PG, Strickland D, van den Biggelaar AH. Ontogeny of Toll-like and NOD-like receptor-mediated innate immune responses in Papua New Guinean infants. Plos One. 7: e36793. PMID 22649499 DOI: 10.1371/journal.pone.0036793  0.01
2012 Holt PG, Sly PD. Viral infections and atopy in asthma pathogenesis: new rationales for asthma prevention and treatment. Nature Medicine. 18: 726-35. PMID 22561836 DOI: 10.1038/nm.2768  0.01
2012 Cunningham PT, Elliot CE, Lenzo JC, Jarnicki AG, Larcombe AN, Zosky GR, Holt PG, Thomas WR. Sensitizing and Th2 adjuvant activity of cysteine protease allergens. International Archives of Allergy and Immunology. 158: 347-58. PMID 22472801 DOI: 10.1159/000334280  1
2012 Martino D, Holt P, Prescott S. A novel role for interleukin-1 receptor signaling in the developmental regulation of immune responses to endotoxin. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology. 23: 567-72. PMID 22435759 DOI: 10.1111/j.1399-3038.2012.01287.x  1
2012 Holt PG, Strickland DH, Sly PD. Virus infection and allergy in the development of asthma: what is the connection? Current Opinion in Allergy and Clinical Immunology. 12: 151-7. PMID 22356945 DOI: 10.1097/ACI.0b013e3283520166  0.01
2012 Whitehouse AJ, Holt BJ, Serralha M, Holt PG, Kusel MM, Hart PH. Maternal serum vitamin D levels during pregnancy and offspring neurocognitive development. Pediatrics. 129: 485-93. PMID 22331333 DOI: 10.1542/peds.2011-2644  1
2012 White OJ, McKenna KL, Bosco A, H J van den Biggelaar A, Richmond P, Holt PG. A genomics-based approach to assessment of vaccine safety and immunogenicity in children. Vaccine. 30: 1865-74. PMID 22230586 DOI: 10.1016/j.vaccine.2011.12.118  1
2012 Lisciandro JG, Prescott SL, Nadal-Sims MG, Devitt CJ, Pomat W, Siba PM, Holt PG, Strickland D, van den Biggelaar AH. Comparison of neonatal T regulatory cell function in Papua New Guinean and Australian newborns. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology. 23: 173-80. PMID 22192086 DOI: 10.1111/j.1399-3038.2011.01242.x  0.01
2012 van den Biggelaar AH, Pomat WS, Phuanukoonnon S, Michael A, Aho C, Nadal-Sims MA, Devitt CJ, Jacoby PA, Hales BJ, Smith WA, Mitchell T, Wiertsema S, Richmond P, Siba P, Holt PG, et al. Effect of early carriage of Streptococcus pneumoniae on the development of pneumococcal protein-specific cellular immune responses in infancy. The Pediatric Infectious Disease Journal. 31: 243-8. PMID 22189528 DOI: 10.1097/INF.0b013e318245a5a8  0.01
2012 Hales BJ, Chai LY, Elliot CE, Pearce LJ, Zhang G, Heinrich TK, Smith WA, Kusel MM, Holt PG, Sly PD, Thomas WR. Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised children. Thorax. 67: 321-7. PMID 22106019 DOI: 10.1136/thoraxjnl-2011-200650  1
2012 Moore HC, de Klerk N, Holt P, Richmond PC, Lehmann D. Hospitalisation for bronchiolitis in infants is more common after elective caesarean delivery. Archives of Disease in Childhood. 97: 410-4. PMID 22039179 DOI: 10.1136/archdischild-2011-300607  1
2011 Zhang G, Hayden CM, Goldblatt J, Holt P, Le Souëf PN. Th2 Cytokine Levels Distort the Association of IL-10 and IFN-γ with Allergic Phenotypes. Isrn Allergy. 2011: 405813. PMID 23724228 DOI: 10.5402/2011/405813  0.01
2011 Miller MC, Le HT, Dean WL, Holt PA, Chaires JB, Trent JO. Polymorphism and resolution of oncogene promoter quadruplex-forming sequences Organic and Biomolecular Chemistry. 9: 7633-7637. PMID 21938285 DOI: 10.1039/c1ob05891f  1
2011 Fear VS, Burchell JT, Lai SP, Wikstrom ME, Blank F, von Garnier C, Turner DJ, Sly PD, Holt PG, Strickland DS, Stumbles PA. Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific CD4+ T cell proliferation during the induction of inhalation tolerance. Journal of Immunology (Baltimore, Md. : 1950). 187: 4561-70. PMID 21930961 DOI: 10.4049/jimmunol.1004189  0.01
2011 Strickland DH, Holt PG. T regulatory cells in childhood asthma. Trends in Immunology. 32: 420-7. PMID 21798806 DOI: 10.1016/j.it.2011.06.010  0.01
2011 Hong X, Wang G, Liu X, Kumar R, Tsai HJ, Arguelles L, Hao K, Pearson C, Ortiz K, Bonzagni A, Apollon S, Fu L, Caruso D, Pongracic JA, Schleimer R, ... Holt PG, et al. Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood. The Journal of Allergy and Clinical Immunology. 128: 374-81.e2. PMID 21689850 DOI: 10.1016/J.Jaci.2011.05.007  1
2011 van den Biggelaar AH, Pomat W, Bosco A, Phuanukoonnon S, Devitt CJ, Nadal-Sims MA, Siba PM, Richmond PC, Lehmann D, Holt PG. Pneumococcal conjugate vaccination at birth in a high-risk setting: no evidence for neonatal T-cell tolerance. Vaccine. 29: 5414-20. PMID 21645573 DOI: 10.1016/j.vaccine.2011.05.065  0.01
2011 Holt PA, Buscaglia R, Trent JO, Chaires JB. A Discovery Funnel for Nucleic Acid Binding Drug Candidates. Drug Development Research. 72: 178-186. PMID 21566705 DOI: 10.1002/ddr.20414  0.01
2011 Holt PG, Sly PD. Interaction between adaptive and innate immune pathways in the pathogenesis of atopic asthma: operation of a lung/bone marrow axis. Chest. 139: 1165-71. PMID 21540215 DOI: 10.1378/chest.10-2397  0.01
2011 Collins RA, Parsons F, Deverell M, Hollams EM, Holt PG, Sly PD. Risk factors for bronchial hyperresponsiveness in teenagers differ with sex and atopic status. The Journal of Allergy and Clinical Immunology. 128: 301-307.e1. PMID 21497891 DOI: 10.1016/j.jaci.2011.03.016  0.01
2011 Custovic A, Soderstrom L, Ahlstedt S, Sly PD, Simpson A, Holt PG. Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood. The Journal of Allergy and Clinical Immunology. 127: 1480-5. PMID 21492924 DOI: 10.1016/j.jaci.2011.03.014  0.01
2011 Hayden CM, Zhang G, Judge PK, Khoo SK, Laing IA, Turner SW, Goldblatt J, Holt PG, Le Souëf PN. Regulatory role of IL10 genetic variations in determining allergen-induced T(H)2 cytokine responses in children. The Journal of Allergy and Clinical Immunology. 128: 237-239.e8. PMID 21439624 DOI: 10.1016/j.jaci.2011.02.032  1
2011 Sly PD, Holt PG. Role of innate immunity in the development of allergy and asthma. Current Opinion in Allergy and Clinical Immunology. 11: 127-31. PMID 21325945 DOI: 10.1097/ACI.0b013e32834487c6  0.01
2010 Strickland DH, Upham JW, Holt PG. Epithelial-dendritic cell interactions in allergic disorders. Current Opinion in Immunology. 22: 789-94. PMID 21106358 DOI: 10.1016/j.coi.2010.10.019  0.01
2010 Hong X, Tsai HJ, Liu X, Arguelles L, Kumar R, Wang G, Kuptsova-Clarkson N, Pearson C, Ortiz K, Bonzagni A, Apollon S, Fu L, Pongracic JA, Schleimer R, Holt PG, et al. Does genetic regulation of IgE begin in utero? Evidence from T(H)1/T(H)2 gene polymorphisms and cord blood total IgE. The Journal of Allergy and Clinical Immunology. 126: 1059-67, 1067.e1. PMID 21050946 DOI: 10.1016/J.Jaci.2010.08.029  1
2010 Thornton CA, Macfarlane TV, Holt PG. The hygiene hypothesis revisited: role of materno-fetal interactions. Current Allergy and Asthma Reports. 10: 444-52. PMID 20809222 DOI: 10.1007/s11882-010-0148-5  0.01
2010 Holt PG, Strickland DH. Interactions between innate and adaptive immunity in asthma pathogenesis: new perspectives from studies on acute exacerbations. The Journal of Allergy and Clinical Immunology. 125: 963-72; quiz 973-4. PMID 20394979 DOI: 10.1016/j.jaci.2010.02.011  0.01
2010 Sly PD, Kusel M, Holt PG. Do early-life viral infections cause asthma? The Journal of Allergy and Clinical Immunology. 125: 1202-5. PMID 20304476 DOI: 10.1016/j.jaci.2010.01.024  0.01
2010 Holt PG, Rowe J, Kusel M, Parsons F, Hollams EM, Bosco A, McKenna K, Subrata L, de Klerk N, Serralha M, Holt BJ, Zhang G, Loh R, Ahlstedt S, Sly PD. Toward improved prediction of risk for atopy and asthma among preschoolers: a prospective cohort study. The Journal of Allergy and Clinical Immunology. 125: 653-9, 659.e1-659.e7. PMID 20226300 DOI: 10.1016/j.jaci.2009.12.018  1
2010 Wikstrom ME, Batanero E, Judd SR, Wiqvist K, Holt PG, Stumbles PA. Lung homing T-cell generation is dependent on strength and timing of antigen delivery to lymph nodes Immunology and Cell Biology. 88: 658-666. PMID 20195280 DOI: 10.1038/icb.2010.18  1
2010 White OJ, Rowe J, Richmond P, Marshall H, McIntyre P, Wood N, Holt PG. Th2-polarisation of cellular immune memory to neonatal pertussis vaccination. Vaccine. 28: 2648-52. PMID 20096390 DOI: 10.1016/j.vaccine.2010.01.010  1
2010 Stumbles PA, Strickland DH, Wikstrom ME, Thomas JA, von Garnier C, Holt PG. Identification and isolation of rodent respiratory tract dendritic cells. Methods in Molecular Biology (Clifton, N.J.). 595: 249-63. PMID 19941118 DOI: 10.1007/978-1-60761-421-0_17  0.01
2009 Holt PG. Prophylactic allergen vaccination: current and future perspectives. Arbeiten Aus Dem Paul-Ehrlich-Institut (Bundesinstitut FüR Impfstoffe Und Biomedizinische Arzneimittel) Langen/Hessen. 96: 281-7; discussion 28. PMID 20799472  0.01
2009 Holt PG, Strickland DH, Bosco A, Jahnsen FL. Pathogenic mechanisms of allergic inflammation: atopic asthma as a paradigm. Advances in Immunology. 104: 51-113. PMID 20457116 DOI: 10.1016/S0065-2776(08)04003-0  0.01
2009 Holt PG, Strickland DH. Soothing signals: transplacental transmission of resistance to asthma and allergy. The Journal of Experimental Medicine. 206: 2861-4. PMID 19995954 DOI: 10.1084/jem.20092469  0.01
2009 Tulic MK, Sly PD, Andrews D, Crook M, Davoine F, Odemuyiwa SO, Charles A, Hodder ML, Prescott SL, Holt PG, Moqbel R. Thymic indoleamine 2,3-dioxygenase-positive eosinophils in young children: potential role in maturation of the naive immune system. The American Journal of Pathology. 175: 2043-52. PMID 19815714 DOI: 10.2353/Ajpath.2009.090015  1
2009 Francis JP, Richmond PC, Pomat WS, Michael A, Keno H, Phuanukoonnon S, Nelson JB, Whinnen M, Heinrich T, Smith WA, Prescott SL, Holt PG, Siba PM, Lehmann D, van den Biggelaar AH. Maternal antibodies to pneumolysin but not to pneumococcal surface protein A delay early pneumococcal carriage in high-risk Papua New Guinean infants. Clinical and Vaccine Immunology : Cvi. 16: 1633-8. PMID 19776196 DOI: 10.1128/CVI.00247-09  0.01
2009 Upham JW, Zhang G, Rate A, Yerkovich ST, Kusel M, Sly PD, Holt PG. Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing. The Journal of Allergy and Clinical Immunology. 124: 707-13.e2. PMID 19733903 DOI: 10.1016/j.jaci.2009.07.009  0.01
2009 Hollams EM, Deverell M, Serralha M, Suriyaarachchi D, Parsons F, Zhang G, de Klerk N, Holt BJ, Ladyman C, Sadowska A, Rowe J, Loh R, Sly PD, Holt PG. Elucidation of asthma phenotypes in atopic teenagers through parallel immunophenotypic and clinical profiling Journal of Allergy and Clinical Immunology. 124. PMID 19733295 DOI: 10.1016/j.jaci.2009.06.019  1
2009 Subrata LS, Bizzintino J, Mamessier E, Bosco A, McKenna KL, Wikström ME, Goldblatt J, Sly PD, Hales BJ, Thomas WR, Laing IA, LeSouëf PN, Holt PG. Interactions between innate antiviral and atopic immunoinflammatory pathways precipitate and sustain asthma exacerbations in children. Journal of Immunology (Baltimore, Md. : 1950). 183: 2793-800. PMID 19620293 DOI: 10.4049/jimmunol.0900695  0.01
2009 van den Biggelaar AH, Prescott SL, Roponen M, Nadal-Sims MA, Devitt CJ, Phuanukoonnon S, Pomat W, Tulic MK, Lehmann D, Siba PM, Richmond PC, Holt PG. Neonatal innate cytokine responses to BCG controlling T-cell development vary between populations. The Journal of Allergy and Clinical Immunology. 124: 544-50, 550.e1-2. PMID 19500827 DOI: 10.1016/j.jaci.2009.03.040  0.01
2009 Zosky GR, Larcombe AN, White OJ, Burchell JT, von Garnier C, Holt PG, Turner DJ, Wikstrom ME, Sly PD, Stumbles PA. Airway hyperresponsiveness is associated with activated CD4+ T cells in the airways. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L373-9. PMID 19482896 DOI: 10.1152/ajplung.00053.2009  0.01
2009 Dailey MM, Hait C, Holt PA, Maguire JM, Meier JB, Miller MC, Petraccone L, Trent JO. Structure-based drug design: from nucleic acid to membrane protein targets. Experimental and Molecular Pathology. 86: 141-50. PMID 19454265 DOI: 10.1016/j.yexmp.2009.01.011  0.01
2009 Bosco A, McKenna KL, Firth MJ, Sly PD, Holt PG. A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease. Journal of Immunology (Baltimore, Md. : 1950). 182: 6011-21. PMID 19414752 DOI: 10.4049/jimmunol.0804125  0.01
2009 van den Biggelaar AH, Richmond PC, Pomat WS, Phuanukoonnon S, Nadal-Sims MA, Devitt CJ, Siba PM, Lehmann D, Holt PG. Neonatal pneumococcal conjugate vaccine immunization primes T cells for preferential Th2 cytokine expression: a randomized controlled trial in Papua New Guinea. Vaccine. 27: 1340-7. PMID 19150378 DOI: 10.1016/j.vaccine.2008.12.046  0.01
2009 Holt PA, Ragazzon P, Strekowski L, Chaires JB, Trent JO. Discovery of novel triple helical DNA intercalators by an integrated virtual and actual screening platform Nucleic Acids Research. 37: 1280-1287. PMID 19136469 DOI: 10.1093/Nar/Gkn1043  1
2009 Rate A, Upham JW, Bosco A, McKenna KL, Holt PG. Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: implications for the pathogenesis of infectious and allergic airway disease. Journal of Immunology (Baltimore, Md. : 1950). 182: 72-83. PMID 19109137  0.01
2009 Zhang G, Rowe J, Kusel M, Bosco A, McKenna K, de Klerk N, Sly PD, Holt PG. Interleukin-10/interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history. American Journal of Respiratory and Critical Care Medicine. 179: 205-11. PMID 18996999 DOI: 10.1164/rccm.200803-438OC  0.01
2009 Yerkovich ST, Roponen M, Smith ME, McKenna K, Bosco A, Subrata LS, Mamessier E, Wikström ME, Le Souef P, Sly PD, Holt PG, Upham JW. Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on dendritic cells is associated with a TH2-skewed immune response. The Journal of Allergy and Clinical Immunology. 123: 209-216.e4. PMID 18947863 DOI: 10.1016/j.jaci.2008.09.009  0.01
2008 Holt PG. Primary prevention by early intervention with specific immunotherapy. Drugs of Today (Barcelona, Spain : 1998). 44: 75-7. PMID 19221625  0.01
2008 Holt PG. Prenatal versus postnatal priming of allergen specific immunologic memory: the debate continues. The Journal of Allergy and Clinical Immunology. 122: 717-8. PMID 19014763 DOI: 10.1016/j.jaci.2008.08.019  0.01
2008 Sly PD, Boner AL, Björksten B, Bush A, Custovic A, Eigenmann PA, Gern JE, Gerritsen J, Hamelmann E, Helms PJ, Lemanske RF, Martinez F, Pedersen S, Renz H, Sampson H, ... ... Holt PG, et al. Early identification of atopy in the prediction of persistent asthma in children. Lancet (London, England). 372: 1100-6. PMID 18805338 DOI: 10.1016/S0140-6736(08)61451-8  0.01
2008 Strickland DH, Wikstrom ME, Turner DJ, Holt PG. Mucosal regulatory T cells in airway hyperresponsiveness. Chemical Immunology and Allergy. 94: 40-7. PMID 18802335 DOI: 10.1159/000154855  0.01
2008 Holt PG, Strickland DH. The CD200-CD200R axis in local control of lung inflammation. Nature Immunology. 9: 1011-3. PMID 18711441 DOI: 10.1038/ni0908-1011  0.01
2008 Holt PA, Chaires JB, Trent JO. Molecular docking of intercalators and groove-binders to nucleic acids using Autodock and Surflex. Journal of Chemical Information and Modeling. 48: 1602-15. PMID 18642866 DOI: 10.1021/ci800063v  0.01
2008 Baynam G, Zhang G, Khoo SK, Sly P, Holt P, Goldblatt J, Le Souëf PN. Gender-specific effects of cytokine gene polymorphisms on childhood vaccine responses. Vaccine. 26: 3574-9. PMID 18547691 DOI: 10.1016/j.vaccine.2008.05.011  0.01
2008 Fernandes R, Kusel M, Cyr M, Sehmi R, Holt K, Holt B, Kebadze T, Johnston SL, Sly P, Denburg JA, Holt P. Cord blood hemopoietic progenitor profiles predict acute respiratory symptoms in infancy. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology. 19: 239-47. PMID 18397408 DOI: 10.1111/j.1399-3038.2007.00615.x  0.01
2008 Holt PG, Strickland DH, Wikström ME, Jahnsen FL. Regulation of immunological homeostasis in the respiratory tract. Nature Reviews. Immunology. 8: 142-52. PMID 18204469 DOI: 10.1038/nri2236  0.01
2007 Holt PG, Sly PD. Prevention of allergic respiratory disease in infants: current aspects and future perspectives. Current Opinion in Allergy and Clinical Immunology. 7: 547-55. PMID 17989533 DOI: 10.1097/ACI.0b013e3282f14a17  0.01
2007 Holt PG, Sly PD. Th2 cytokines in the asthma late-phase response. Lancet (London, England). 370: 1396-8. PMID 17950849 DOI: 10.1016/S0140-6736(07)61587-6  0.01
2007 Von Garnier C, Wikstrom ME, Zosky G, Turner DJ, Sly PD, Smith M, Thomas JA, Judd SR, Strickland DH, Holt PG, Stumbles PA. Allergic airways disease develops after an increase in allergen capture and processing in the airway mucosa Journal of Immunology. 179: 5748-5759. PMID 17947647  1
2007 Yerkovich ST, Wikström ME, Suriyaarachchi D, Prescott SL, Upham JW, Holt PG. Postnatal development of monocyte cytokine responses to bacterial lipopolysaccharide. Pediatric Research. 62: 547-52. PMID 17805207 DOI: 10.1203/PDR.0b013e3181568105  0.01
2007 Tulic MK, Hurrelbrink RJ, Prêle CM, Laing IA, Upham JW, Le Souef P, Sly PD, Holt PG. TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 179: 132-40. PMID 17579031  0.01
2007 Rowe J, Kusel M, Holt BJ, Suriyaarachchi D, Serralha M, Hollams E, Yerkovich ST, Subrata LS, Ladyman C, Sadowska A, Gillett J, Fisher E, Loh R, Soderstrom L, Ahlstedt S, ... ... Holt PG, et al. Prenatal versus postnatal sensitization to environmental allergens in a high-risk birth cohort. The Journal of Allergy and Clinical Immunology. 119: 1164-73. PMID 17412403 DOI: 10.1016/j.jaci.2007.02.016  1
Show low-probability matches.