Mark Howarth - Publications

Affiliations: 
University of Oxford, Oxford, United Kingdom 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Khairil Anuar INA, Banerjee A, Keeble AH, Carella A, Nikov GI, Howarth M. Spy&Go purification of SpyTag-proteins using pseudo-SpyCatcher to access an oligomerization toolbox. Nature Communications. 10: 1734. PMID 30988307 DOI: 10.1038/s41467-019-09678-w  0.72
2019 Keeble AH, Howarth M. Insider information on successful covalent protein coupling with help from SpyBank. Methods in Enzymology. 617: 443-461. PMID 30784412 DOI: 10.1016/bs.mie.2018.12.010  0.72
2018 Wieduwild R, Howarth M. Assembling and decorating hyaluronan hydrogels with twin protein superglues to mimic cell-cell interactions. Biomaterials. 180: 253-264. PMID 30053659 DOI: 10.1016/j.biomaterials.2018.07.020  1
2018 Brune KD, Howarth M. New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue. Frontiers in Immunology. 9: 1432. PMID 29997617 DOI: 10.3389/fimmu.2018.01432  1
2017 Banerjee A, Howarth M. Nanoteamwork: covalent protein assembly beyond duets towards protein ensembles and orchestras. Current Opinion in Biotechnology. 51: 16-23. PMID 29172131 DOI: 10.1016/j.copbio.2017.10.006  0.6
2017 Keeble AH, Banerjee A, Reddington SC, Ferla MP, Howarth M, Khairil Anuar INA. Evolving accelerated amidation by SpyTag/SpyCatcher to analyze membrane dynamics. Angewandte Chemie (International Ed. in English). PMID 29024296 DOI: 10.1002/anie.201707623  0.72
2017 Leneghan DB, Miura K, Taylor IJ, Li Y, Jin J, Brune KD, Bachmann MF, Howarth M, Long CA, Biswas S. Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines. Scientific Reports. 7: 3811. PMID 28630474 DOI: 10.1038/s41598-017-03798-3  1
2017 Brune K, Buldun C, Li Y, Taylor I, Brod F, Biswas S, Howarth M. Dual plug-and-display synthetic assembly using orthogonal reactive proteins for twin antigen immunization. Bioconjugate Chemistry. PMID 28437083 DOI: 10.1021/acs.bioconjchem.7b00174  0.32
2016 Schoene C, Bennett SP, Howarth M. SpyRing interrogation: analyzing how enzyme resilience can be achieved with phytase and distinct cyclization chemistries. Scientific Reports. 6: 21151. PMID 26861173 DOI: 10.1038/srep21151  0.64
2016 Veggiani G, Nakamura T, Brenner MD, Gayet RV, Yan J, Robinson CV, Howarth M. Programmable polyproteams built using twin peptide superglues. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787909 DOI: 10.1073/pnas.1519214113  0.84
2016 Brune KD, Leneghan DB, Brian IJ, Ishizuka AS, Bachmann MF, Draper SJ, Biswas S, Howarth M. Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization. Scientific Reports. 6: 19234. PMID 26781591 DOI: 10.1038/srep19234  0.84
2015 Reddington SC, Howarth M. Secrets of a covalent interaction for biomaterials and biotechnology: SpyTag and SpyCatcher. Current Opinion in Chemical Biology. 29: 94-9. PMID 26517567 DOI: 10.1016/j.cbpa.2015.10.002  0.52
2014 Veggiani G, Zakeri B, Howarth M. Superglue from bacteria: unbreakable bridges for protein nanotechnology. Trends in Biotechnology. 32: 506-12. PMID 25168413 DOI: 10.1016/j.tibtech.2014.08.001  0.32
2014 Fairhead M, Shen D, Chan LK, Lowe ED, Donohoe TJ, Howarth M. Love-Hate ligands for high resolution analysis of strain in ultra-stable protein/small molecule interaction. Bioorganic & Medicinal Chemistry. 22: 5476-86. PMID 25128469 DOI: 10.1016/j.bmc.2014.07.029  0.84
2014 Fairhead M, Veggiani G, Lever M, Yan J, Mesner D, Robinson CV, Dushek O, van der Merwe PA, Howarth M. SpyAvidin hubs enable precise and ultrastable orthogonal nanoassembly. Journal of the American Chemical Society. 136: 12355-63. PMID 25111182 DOI: 10.1021/ja505584f  0.32
2014 Schoene C, Fierer JO, Bennett SP, Howarth M. SpyTag/SpyCatcher cyclization confers resilience to boiling on a mesophilic enzyme. Angewandte Chemie (International Ed. in English). 53: 6101-4. PMID 24817566 DOI: 10.1002/anie.201402519  0.64
2014 Fierer JO, Veggiani G, Howarth M. SpyLigase peptide-peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture. Proceedings of the National Academy of Sciences of the United States of America. 111: E1176-81. PMID 24639550 DOI: 10.1073/pnas.1315776111  0.44
2014 Li L, Fierer JO, Rapoport TA, Howarth M. Structural analysis and optimization of the covalent association between SpyCatcher and a peptide Tag. Journal of Molecular Biology. 426: 309-17. PMID 24161952 DOI: 10.1016/j.jmb.2013.10.021  0.84
2014 Fairhead M, Krndija D, Lowe ED, Howarth M. Plug-and-play pairing via defined divalent streptavidins. Journal of Molecular Biology. 426: 199-214. PMID 24056174 DOI: 10.1016/j.jmb.2013.09.016  0.36
2013 Jain J, Veggiani G, Howarth M. Cholesterol loading and ultrastable protein interactions determine the level of tumor marker required for optimal isolation of cancer cells. Cancer Research. 73: 2310-21. PMID 23378340 DOI: 10.1158/0008-5472.CAN-12-2956  0.32
2013 Koner AL, Krndija D, Hou Q, Sherratt DJ, Howarth M. Hydroxy-terminated conjugated polymer nanoparticles have near-unity bright fraction and reveal cholesterol-dependence of IGF1R nanodomains. Acs Nano. 7: 1137-44. PMID 23330847 DOI: 10.1021/nn3042122  0.36
2012 Liu DS, Phipps WS, Loh KH, Howarth M, Ting AY. Quantum dot targeting with lipoic acid ligase and HaloTag for single-molecule imaging on living cells. Acs Nano. 6: 11080-7. PMID 23181687 DOI: 10.1021/nn304793z  0.84
2012 Zakeri B, Fierer JO, Celik E, Chittock EC, Schwarz-Linek U, Moy VT, Howarth M. Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin. Proceedings of the National Academy of Sciences of the United States of America. 109: E690-7. PMID 22366317 DOI: 10.1073/pnas.1115485109  0.84
2011 Dalchau N, Phillips A, Goldstein LD, Howarth M, Cardelli L, Emmott S, Elliott T, Werner JM. A peptide filtering relation quantifies MHC class I peptide optimization. Plos Computational Biology. 7: e1002144. PMID 22022238 DOI: 10.1371/journal.pcbi.1002144  0.84
2011 Alakoskela JM, Koner AL, Rudnicka D, Köhler K, Howarth M, Davis DM. Mechanisms for size-dependent protein segregation at immune synapses assessed with molecular rulers. Biophysical Journal. 100: 2865-74. PMID 21689519 DOI: 10.1016/j.bpj.2011.05.013  0.84
2011 Chivers CE, Koner AL, Lowe ED, Howarth M. How the biotin-streptavidin interaction was made even stronger: investigation via crystallography and a chimaeric tetramer. The Biochemical Journal. 435: 55-63. PMID 21241253 DOI: 10.1042/BJ20101593  0.36
2010 Aleksic T, Chitnis MM, Perestenko OV, Gao S, Thomas PH, Turner GD, Protheroe AS, Howarth M, Macaulay VM. Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells. Cancer Research. 70: 6412-9. PMID 20710042 DOI: 10.1158/0008-5472.CAN-10-0052  0.84
2010 Chivers CE, Crozat E, Chu C, Moy VT, Sherratt DJ, Howarth M. A streptavidin variant with slower biotin dissociation and increased mechanostability. Nature Methods. 7: 391-3. PMID 20383133 DOI: 10.1038/nmeth.1450  0.84
2010 Crozat E, Meglio A, Allemand JF, Chivers CE, Howarth M, Vénien-Bryan C, Grainge I, Sherratt DJ. Separating speed and ability to displace roadblocks during DNA translocation by FtsK. The Embo Journal. 29: 1423-33. PMID 20379135 DOI: 10.1038/emboj.2010.29  0.84
2009 Holm L, Moody P, Howarth M. Electrophilic affibodies forming covalent bonds to protein targets. The Journal of Biological Chemistry. 284: 32906-13. PMID 19759009 DOI: 10.1074/jbc.M109.034322  0.84
2008 Howarth M, Liu W, Puthenveetil S, Zheng Y, Marshall LF, Schmidt MM, Wittrup KD, Bawendi MG, Ting AY. Monovalent, reduced-size quantum dots for imaging receptors on living cells. Nature Methods. 5: 397-9. PMID 18425138 DOI: 10.1038/nmeth.1206  0.84
2008 Howarth M, Ting AY. Imaging proteins in live mammalian cells with biotin ligase and monovalent streptavidin. Nature Protocols. 3: 534-45. PMID 18323822 DOI: 10.1038/nprot.2008.20  0.84
2008 Liu W, Howarth M, Greytak AB, Zheng Y, Nocera DG, Ting AY, Bawendi MG. Compact biocompatible quantum dots functionalized for cellular imaging. Journal of the American Chemical Society. 130: 1274-84. PMID 18177042 DOI: 10.1021/ja076069p  0.84
2006 Howarth M, Chinnapen DJ, Gerrow K, Dorrestein PC, Grandy MR, Kelleher NL, El-Husseini A, Ting AY. A monovalent streptavidin with a single femtomolar biotin binding site. Nature Methods. 3: 267-73. PMID 16554831 DOI: 10.1038/nmeth861  0.84
2006 Howarth M, Ting AY. Giving cells a new sugar-coating. Nature Chemical Biology. 2: 127-8. PMID 16485002 DOI: 10.1038/nchembio0306-127  0.84
2005 Howarth M, Takao K, Hayashi Y, Ting AY. Targeting quantum dots to surface proteins in living cells with biotin ligase. Proceedings of the National Academy of Sciences of the United States of America. 102: 7583-8. PMID 15897449 DOI: 10.1073/pnas.0503125102  0.84
2005 Chen I, Howarth M, Lin W, Ting AY. Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase. Nature Methods. 2: 99-104. PMID 15782206 DOI: 10.1038/nmeth735  0.84
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