Douglas Young - Publications

2004-2009 North Carolina State University, Raleigh, NC 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Young DD, Schultz PG. Playing with the molecules of life. Acs Chemical Biology. PMID 29345901 DOI: 10.1021/Acschembio.7B00974  0.84
2015 Maza JC, Nimmo ZM, Young DD. Expanding the scope of alkyne-mediated bioconjugations utilizing unnatural amino acids. Chemical Communications (Cambridge, England). PMID 26499242 DOI: 10.1039/c5cc08287k  1
2015 Maza JC, McKenna JR, Raliski BK, Freedman MT, Young DD. Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations. Bioconjugate Chemistry. 26: 1884-9. PMID 26287719 DOI: 10.1021/acs.bioconjchem.5b00424  1
2015 Lampkowski JS, Villa JK, Young TS, Young DD. Development and Optimization of Glaser-Hay Bioconjugations. Angewandte Chemie (International Ed. in English). PMID 26088803 DOI: 10.1002/Anie.201502676  1
2015 Govan JM, Young DD, Lively MO, Deiters A. Optically Triggered Immune Response through Photocaged Oligonucleotides. Tetrahedron Letters. 56: 3639-3642. PMID 26034339 DOI: 10.1016/J.Tetlet.2015.01.165  0.48
2015 Lampkowski JS, Maza JC, Verma S, Young DD. Optimization of solid-supported Glaser-Hay reactions in the microwave. Molecules (Basel, Switzerland). 20: 5276-85. PMID 25812149 DOI: 10.3390/Molecules20045276  1
2015 Lampkowski JS, Durham CE, Padilla MS, Young DD. Preparation of asymmetrical polyynes by a solid-supported Glaser-Hay reaction. Organic & Biomolecular Chemistry. 13: 424-7. PMID 25371282 DOI: 10.1039/c4ob02196g  1
2014 Raliski BK, Howard CA, Young DD. Site-specific protein immobilization using unnatural amino acids. Bioconjugate Chemistry. 25: 1916-20. PMID 25340826 DOI: 10.1021/bc500443h  1
2014 Rust HL, Subramanian V, West GM, Young DD, Schultz PG, Thompson PR. Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. Acs Chemical Biology. 9: 649-55. PMID 24358983 DOI: 10.1021/Cb400859Z  1
2013 Govan JM, Young DD, Lusic H, Liu Q, Lively MO, Deiters A. Optochemical control of RNA interference in mammalian cells. Nucleic Acids Research. 41: 10518-28. PMID 24021631 DOI: 10.1093/Nar/Gkt806  1
2011 Young DD, Jockush S, Turro NJ, Schultz PG. Synthetase polyspecificity as a tool to modulate protein function. Bioorganic & Medicinal Chemistry Letters. 21: 7502-4. PMID 22041062 DOI: 10.1016/J.Bmcl.2011.09.108  1
2011 Georgianna WE, Young DD. Development and utilization of non-coding RNA-small molecule interactions. Organic & Biomolecular Chemistry. 9: 7969-78. PMID 21993406 DOI: 10.1039/c1ob06324c  0.8
2011 Minnihan EC, Young DD, Schultz PG, Stubbe J. Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase. Journal of the American Chemical Society. 133: 15942-5. PMID 21913683 DOI: 10.1021/Ja207719F  1
2011 Young TS, Young DD, Ahmad I, Louis JM, Benkovic SJ, Schultz PG. Evolution of cyclic peptide protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 11052-6. PMID 21690365 DOI: 10.1073/Pnas.1108045108  1
2011 Dush MK, McIver AL, Parr MA, Young DD, Fisher J, Newman DR, Sannes PL, Hauck ML, Deiters A, Nascone-Yoder N. Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chemistry & Biology. 18: 252-63. PMID 21338922 DOI: 10.1016/J.Chembiol.2010.12.008  1
2011 Young DD, Young TS, Jahnz M, Ahmad I, Spraggon G, Schultz PG. An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity. Biochemistry. 50: 1894-900. PMID 21280675 DOI: 10.1021/Bi101929E  1
2011 Karginov AV, Zou Y, Shirvanyants D, Kota P, Dokholyan NV, Young DD, Hahn KM, Deiters A. Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. Journal of the American Chemical Society. 133: 420-3. PMID 21162531 DOI: 10.1021/Ja109630V  1
2011 Young DD, Deiters A. Chemo- and Regioselectivity Enhancement in Solid-Supported Reactions Solid-Phase Organic Synthesis: Concepts, Strategies, and Applications. 171-204. DOI: 10.1002/9781118141649.ch6  1
2010 Young DD, Connelly CM, Grohmann C, Deiters A. Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. Journal of the American Chemical Society. 132: 7976-81. PMID 20527935 DOI: 10.1021/Ja910275U  1
2010 Young DD, Lively MO, Deiters A. Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. Journal of the American Chemical Society. 132: 6183-93. PMID 20392038 DOI: 10.1021/Ja100710J  1
2010 Chou C, Young DD, Deiters A. Photocaged t7 RNA polymerase for the light activation of transcription and gene function in pro- and eukaryotic cells. Chembiochem : a European Journal of Chemical Biology. 11: 972-7. PMID 20301166 DOI: 10.1002/Cbic.201000041  1
2010 Wilkins BJ, Marionni S, Young DD, Liu J, Wang Y, Di Salvo ML, Deiters A, Cropp TA. Site-specific incorporation of fluorotyrosines into proteins in Escherichia coli by photochemical disguise. Biochemistry. 49: 1557-9. PMID 20136096 DOI: 10.1021/Bi100013S  1
2009 Chou C, Young DD, Deiters A. A light-activated DNA polymerase. Angewandte Chemie (International Ed. in English). 48: 5950-3. PMID 19569148 DOI: 10.1002/Anie.200901115  1
2009 Young DD, Govan JM, Lively MO, Deiters A. Photochemical regulation of restriction endonuclease activity. Chembiochem : a European Journal of Chemical Biology. 10: 1612-6. PMID 19533711 DOI: 10.1002/Cbic.200900090  1
2009 Edwards WF, Young DD, Deiters A. The effect of microwave irradiation on DNA hybridization. Organic & Biomolecular Chemistry. 7: 2506-8. PMID 19503920 DOI: 10.1039/B903609A  1
2009 Bereman MS, Young DD, Deiters A, Muddiman DC. Development of a robust and high throughput method for profiling N-linked glycans derived from plasma glycoproteins by NanoLC-FTICR mass spectrometry. Journal of Proteome Research. 8: 3764-70. PMID 19435342 DOI: 10.1021/Pr9002323  1
2009 Edwards WF, Young DD, Deiters A. Light-activated Cre recombinase as a tool for the spatial and temporal control of gene function in mammalian cells. Acs Chemical Biology. 4: 441-5. PMID 19413301 DOI: 10.1021/Cb900041S  1
2009 Young DD, Lusic H, Lively MO, Deiters A. Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization. Nucleic Acids Research. 37: e58. PMID 19293272 DOI: 10.1093/Nar/Gkp150  1
2009 Young DD, Garner RA, Yoder JA, Deiters A. Light-activation of gene function in mammalian cells via ribozymes. Chemical Communications (Cambridge, England). 568-70. PMID 19283293 DOI: 10.1039/B819375D  1
2009 Young DD, Teske JA, Deiters A. Open-vessel microwave-mediated [2+2+2]-cyclotrimerization reactions Synthesis. 3785-3790. DOI: 10.1055/S-0029-1218149  1
2008 Young DD, Lusic H, Lively MO, Yoder JA, Deiters A. Gene silencing in mammalian cells with light-activated antisense agents. Chembiochem : a European Journal of Chemical Biology. 9: 2937-40. PMID 19021142 DOI: 10.1002/Cbic.200800627  1
2008 McIver A, Young DD, Deiters A. A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine. Chemical Communications (Cambridge, England). 4750-2. PMID 18830481 DOI: 10.1039/B811068A  1
2008 Zou Y, Young DD, Cruz-Montanez A, Deiters A. Synthesis of anthracene and azaanthracene fluorophores via [2+2+2] cyclotrimerization reactions. Organic Letters. 10: 4661-4. PMID 18816125 DOI: 10.1021/Ol8019549  1
2008 Young DD, Torres-Kolbus J, Deiters A. Microwave-assisted synthesis of unnatural amino acids. Bioorganic & Medicinal Chemistry Letters. 18: 5478-80. PMID 18809329 DOI: 10.1016/J.Bmcl.2008.09.025  1
2008 Gumireddy K, Young DD, Xiong X, Hogenesch JB, Huang Q, Deiters A. Small-molecule inhibitors of microrna miR-21 function. Angewandte Chemie (International Ed. in English). 47: 7482-4. PMID 18712719 DOI: 10.1002/Anie.200801555  1
2008 Young DD, Nichols J, Kelly RM, Deiters A. Microwave activation of enzymatic catalysis. Journal of the American Chemical Society. 130: 10048-9. PMID 18613673 DOI: 10.1021/Ja802404G  1
2008 Young DD, Deiters A. Light-regulated RNA-small molecule interactions. Chembiochem : a European Journal of Chemical Biology. 9: 1225-8. PMID 18404761 DOI: 10.1002/Cbic.200800051  1
2008 Young DD, Edwards WF, Lusic H, Lively MO, Deiters A. Light-triggered polymerase chain reaction. Chemical Communications (Cambridge, England). 462-4. PMID 18188468 DOI: 10.1039/B715152G  1
2007 Senaiar RS, Teske JA, Young DD, Deiters A. Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization. The Journal of Organic Chemistry. 72: 7801-4. PMID 17824655 DOI: 10.1021/Jo7013565  1
2007 Young DD, Sripada L, Deiters A. Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry. Journal of Combinatorial Chemistry. 9: 735-8. PMID 17658900 DOI: 10.1021/Cc070068B  1
2007 Young DD, Deiters A. A general approach to chemo- and regioselective cyclotrimerization reactions. Angewandte Chemie (International Ed. in English). 46: 5187-90. PMID 17526034 DOI: 10.1002/Anie.200700802  1
2007 Young DD, Deiters A. Photochemical activation of protein expression in bacterial cells. Angewandte Chemie (International Ed. in English). 46: 4290-2. PMID 17458846 DOI: 10.1002/Anie.200700057  1
2007 Lusic H, Young DD, Lively MO, Deiters A. Photochemical DNA activation. Organic Letters. 9: 1903-6. PMID 17447773 DOI: 10.1021/Ol070455U  1
2007 Young DD, Deiters A. Photochemical control of biological processes. Organic & Biomolecular Chemistry. 5: 999-1005. PMID 17377650 DOI: 10.1039/B616410M  1
2006 Young DD, Senaiar RS, Deiters A. Solid-supported [2+2+2] cyclotrimerizations. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 5563-8. PMID 16755631 DOI: 10.1002/Chem.200501360  1
2006 Senaiar RS, Young DD, Deiters A. Pyridines via solid-supported [2 + 2 + 2] cyclotrimerization. Chemical Communications (Cambridge, England). 1313-5. PMID 16538258 DOI: 10.1039/B515901F  1
2006 Young DD, Deiters A. Photochemical hammerhead ribozyme activation. Bioorganic & Medicinal Chemistry Letters. 16: 2658-61. PMID 16513347 DOI: 10.1016/J.Bmcl.2006.02.034  1
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