Jun Wang, M.Sc. - Publications

Affiliations: 
2014- Pharmacology and Toxicology University of Arizona, Tucson, AZ 
Website:
http://www.pharmacy.arizona.edu/directory/profile/jun-wang-phd

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wang C, Lu T, Xu R, Chang X, Luo S, Peng B, Wang J, Yao L, Wang K, Shen Z, Zhao J, Zhang L. A bioinformatics-based immune-related prognostic index for lung adenocarcinoma that predicts patient response to immunotherapy and common treatments. Journal of Thoracic Disease. 14: 2131-2146. PMID 35813746 DOI: 10.21037/jtd-22-494  0.311
2022 Lu T, Xu R, Wang CH, Zhao JY, Peng B, Wang J, Zhang LY. Identification of Tumor Antigens and Immune Subtypes of Esophageal Squamous Cell Carcinoma for mRNA Vaccine Development. Frontiers in Genetics. 13: 853113. PMID 35734437 DOI: 10.3389/fgene.2022.853113  0.356
2022 Zhang K, Wang J, Ge Y, Ma J, Zhou Q. A new species from Xinjiang Uygur Autonomous Region (China) with a key to Xinjiang freshwater gammarids (Crustacea, Amphipoda, Gammaridae). Zookeys. 1090: 129-147. PMID 35586839 DOI: 10.3897/zookeys.1090.78834  0.368
2022 Xu R, Lu T, Zhao J, Wang J, Peng B, Zhang L. Identification of Tumor Antigens and Immune Subtypes in Lung Adenocarcinoma for mRNA Vaccine Development. Frontiers in Cell and Developmental Biology. 10: 815596. PMID 35265614 DOI: 10.3389/fcell.2022.815596  0.347
2022 Wang J, Yu X, Gong W, Liu X, Park KS, Ma A, Tsai YH, Shen Y, Onikubo T, Pi WC, Allison DF, Liu J, Chen WY, Cai L, Roeder RG, et al. EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis. Nature Cell Biology. PMID 35210568 DOI: 10.1038/s41556-022-00850-x  0.306
2022 Hu Y, Jo H, DeGrado WF, Wang J. Brilacidin, a COVID-19 Drug Candidate, demonstrates broad-spectrum antiviral activity against human coronaviruses OC43, 229E and NL63 through targeting both the virus and the host cell. Journal of Medical Virology. PMID 35080027 DOI: 10.1002/jmv.27616  0.58
2021 Xu R, Lu T, Zhao J, Li Q, Wang J, Peng B, Liu J, Zhang P, Qu L, Chang X, Yao L, Zhang L. Identification of ubiquitinated substrate proteins and their gene expression patterns in lung adenocarcinoma. Annals of Translational Medicine. 9: 1692. PMID 34988201 DOI: 10.21037/atm-21-5645  0.324
2021 Thomaston JL, Samways ML, Konstantinidi A, Ma C, Hu Y, Bruce Macdonald HE, Wang J, Essex JW, DeGrado WF, Kolocouris A. Rimantadine Binds to and Inhibits the Influenza A M2 Proton Channel without Enantiomeric Specificity. Biochemistry. PMID 34342217 DOI: 10.1021/acs.biochem.1c00437  0.627
2021 Lu T, Xu R, Li Q, Zhao JY, Peng B, Zhang H, Guo JD, Zhang SQ, Li HW, Wang J, Zhang LY. Systematic profiling of ferroptosis gene signatures predicts prognostic factors in esophageal squamous cell carcinoma. Molecular Therapy Oncolytics. 21: 134-143. PMID 33981829 DOI: 10.1016/j.omto.2021.02.011  0.323
2021 Wang Y, He K, Sheng B, Lei X, Tao W, Zhu X, Wei Z, Fu R, Wang A, Bai S, Zhang Z, Hong N, Ye C, Tian Y, Wang J, et al. The RNA helicase Dhx15 mediates Wnt-induced antimicrobial protein expression in Paneth cells. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33483420 DOI: 10.1073/pnas.2017432118  0.567
2021 Wang J, Liu LG, Jiao WQ, Yang H, Liu J, Liu D. Phenylboronic acid-conjugated chitosan nanoparticles for high loading and efficient delivery of curcumin. Carbohydrate Polymers. 256: 117497. PMID 33483024 DOI: 10.1016/j.carbpol.2020.117497  0.542
2020 Tzitzoglaki C, McGuire K, Lagarias P, Konstantinidi A, Hoffmann A, Fokina NA, Ma C, Papanastasiou IP, Schreiner PR, Vazquez S, Schmidtke M, Wang J, Busath DD, Kolocouris A. Chemical Probes for Blocking of Influenza A M2 WT and S31N Channels. Acs Chemical Biology. PMID 32786258 DOI: 10.1021/Acschembio.0C00553  0.363
2020 Ma C, Hu Y, Zhang J, Wang J. Pharmacological characterization of the mechanism of action of R523062, a promising antiviral for enterovirus D68. Acs Infectious Diseases. PMID 32692536 DOI: 10.1021/Acsinfecdis.0C00383  0.322
2020 Musharrafieh R, Kitamura N, Hu Y, Wang J. Development of broad-spectrum enterovirus antivirals based on quinoline scaffold. Bioorganic Chemistry. 101: 103981. PMID 32559580 DOI: 10.1016/J.Bioorg.2020.103981  0.312
2020 Ma C, Sacco MD, Hurst B, Townsend JA, Hu Y, Szeto T, Zhang X, Tarbet B, Marty MT, Chen Y, Wang J. Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease. Cell Research. PMID 32541865 DOI: 10.1038/S41422-020-0356-Z  0.373
2020 Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Ngan Pham NY, Molnar G, Streicher JM, Patek M, ... ... Wang J, et al. A modulator of the low-voltage activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies. Pain. PMID 32541387 DOI: 10.1097/J.Pain.0000000000001955  0.318
2020 Pi WC, Wang J, Shimada M, Lin JW, Geng H, Lee YL, Li D, Wang GG, Roeder RG, Chen WY. E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia. Blood. PMID 32276273 DOI: 10.1182/blood.2019003312  0.308
2020 Jalily PH, Duncan MC, Fedida D, Wang J, Tietjen I. Put a cork in it: Plugging the M2 viral ion channel to sink influenza. Antiviral Research. 104780. PMID 32229237 DOI: 10.1016/J.Antiviral.2020.104780  0.363
2020 Song H, Wang J, Zhang K, Zhang M, Hui R, Sui T, Yang L, Du W, Dong Z. A 4-year field measurement of NO emissions from a maize-wheat rotation system as influenced by partial organic substitution for synthetic fertilizer. Journal of Environmental Management. 263: 110384. PMID 32174526 DOI: 10.1016/j.jenvman.2020.110384  0.366
2020 Guo YF, Duan JJ, Wang J, Li L, Wang D, Liu XZ, Yang J, Zhang HR, Lv J, Yang YJ, Yang ZY, Cai J, Liao XM, Tang T, Huang TT, et al. Inhibition of the ALDH18A1-MYCN positive feedback loop attenuates -amplified neuroblastoma growth. Science Translational Medicine. 12. PMID 32075946 DOI: 10.1126/scitranslmed.aax8694  0.303
2020 Thomaston JL, Konstantinidi A, Liu L, Lambrinidis G, Tan J, Caffrey M, Wang J, Degrado WF, Kolocouris A. X-ray crystal structures of the influenza M2 proton channel drug-resistant V27A mutant bound to a spiro-adamantyl amine inhibitor reveal the mechanism of adamantane resistance. Biochemistry. PMID 31894969 DOI: 10.2210/Pdb6Nv1/Pdb  0.665
2019 Zhang J, Hu Y, Wu N, Wang J. Discovery of Influenza polymerase PA-PB1 Interaction Inhibitors Using an In Vitro Split-Luciferase Complementation-based Assay. Acs Chemical Biology. PMID 31714745 DOI: 10.1021/Acschembio.9B00552  0.357
2019 Musharrafieh R, Ma C, Wang J. Discovery of M2 channel blockers targeting the drug-resistant double mutants M2-S31N/L26I and M2-S31N/V27A from the influenza A viruses. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105124. PMID 31669761 DOI: 10.1016/J.Ejps.2019.105124  0.369
2019 Ma C, Hu Y, Zhang J, Musharrafieh R, Wang J. A Novel Capsid Binding Inhibitor Displays Potent Antiviral Activity against Enterovirus D68. Acs Infectious Diseases. PMID 31532189 DOI: 10.1021/Acsinfecdis.9B00284  0.325
2019 Thomaston JL, Wu Y, Polizzi N, Liu L, Wang J, DeGrado WF. X-ray crystal structure of the influenza A M2 proton channel S31N mutant in two conformational states: an open and shut case. Journal of the American Chemical Society. PMID 31184871 DOI: 10.1021/Jacs.9B02196  0.647
2019 Musharrafieh R, Lagarias P, Ma C, Tan G, Kolocouris A, Wang J. The L46P mutant confers a novel allosteric mechanism of resistance towards the influenza A virus M2 S31N proton channel blockers. Molecular Pharmacology. PMID 31175183 DOI: 10.1124/Mol.119.116640  0.359
2019 Zhang J, Hu Y, Hau R, Musharrafieh R, Ma C, Zhou X, Chen Y, Wang J. Identification of NMS-873, an allosteric and specific p97 inhibitor, as a broad antiviral against both influenza A and B viruses. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 133: 86-94. PMID 30930289 DOI: 10.1016/J.Ejps.2019.03.020  0.361
2019 Wang J, Xu SL, Duan JJ, Yi L, Guo YF, Shi Y, Li L, Yang ZY, Liao XM, Cai J, Zhang YQ, Xiao HL, Yin L, Wu H, Zhang JN, et al. Author Correction: Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nature Neuroscience. PMID 30903095 DOI: 10.1038/s41593-019-0388-1  0.305
2019 Musharrafieh R, Ma C, Zhang J, Hu Y, Diesing JM, Marty MT, Wang J. Validating Enterovirus D68-2A as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2A Inhibitor. Journal of Virology. PMID 30674624 DOI: 10.1128/Jvi.02221-18  0.309
2019 Wang J, Xu SL, Duan JJ, Yi L, Guo YF, Shi Y, Li L, Yang ZY, Liao XM, Cai J, Zhang YQ, Xiao HL, Yin L, Wu H, Zhang JN, et al. Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nature Neuroscience. 22: 91-105. PMID 30559479 DOI: 10.1038/s41593-018-0285-z  0.331
2019 Thomaston J, Wu Y, Liu L, Wang J, DeGrado W. Structural basis of adamantane resistance in the influenza A M2 proton channel Acta Crystallographica Section A. 75. DOI: 10.1107/S2053273319094166  0.646
2018 Hu Y, Hau RK, Wang Y, Tuohy P, Zhang Y, Xu S, Ma C, Wang J. Structure-Property Relationship Studies of Influenza A Virus AM2-S31N Proton Channel Blockers. Acs Medicinal Chemistry Letters. 9: 1111-1116. PMID 30429954 DOI: 10.1021/Acsmedchemlett.8B00336  0.375
2018 Wang J, Huang Y, Xu K, Zhang X, Sun H, Fan L, Yan M. White spot syndrome virus (WSSV) infection impacts intestinal microbiota composition and function in Litopenaeus vannamei. Fish & Shellfish Immunology. PMID 30278220 DOI: 10.1016/j.fsi.2018.09.076  0.462
2018 Thomaston JL, Polizzi NF, Konstantinidi A, Wang J, Kolocouris A, DeGrado WF. Inhibitors of the M2 proton channel engage and disrupt transmembrane networks of hydrogen-bonded waters. Journal of the American Chemical Society. PMID 30165017 DOI: 10.1021/Jacs.8B06741  0.666
2018 Zhang J, Hu Y, Musharrafieh RG, Yin H, Wang J. Focusing on the influenza virus polymerase complex: recent progress in drug discovery and assay development. Current Medicinal Chemistry. PMID 29984646 DOI: 10.2174/0929867325666180706112940  0.604
2018 Zhao X, Li R, Zhou Y, Xiao M, Ma C, Yang Z, Zeng S, Du Q, Yang C, Jiang H, Hu Y, Wang K, Mok CKP, Sun P, Dong J, ... ... Wang J, et al. Discovery of Highly Potent Pinanamine-Based Inhibitors Against Amantadine- and Oseltamivir-resistant Influenza A Viruses. Journal of Medicinal Chemistry. PMID 29799746 DOI: 10.1021/Acs.Jmedchem.8B00042  0.356
2018 Mandour YM, Breitinger U, Ma C, Wang J, Boeckler FM, Breitinger HG, Zlotos DP. Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7. Drug Design, Development and Therapy. 12: 1019-1031. PMID 29750015 DOI: 10.2147/Dddt.S157104  0.356
2018 Zhang J, Hu Y, Foley C, Wang Y, Musharrafieh R, Xu S, Zhang Y, Ma C, Hulme C, Wang J. Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance. Scientific Reports. 8: 4653. PMID 29545578 DOI: 10.1038/S41598-018-22875-9  0.352
2018 Drakopoulos A, Tzitzoglaki C, McGuire K, Hoffmann A, Konstantinidi A, Kolokouris D, Ma C, Freudenberger K, Hutterer J, Gauglitz G, Wang J, Schmidtke M, Busath DD, Kolocouris A. Unraveling the Binding, Proton Blockage, and Inhibition of Influenza M2 WT and S31N by Rimantadine Variants. Acs Medicinal Chemistry Letters. 9: 198-203. PMID 29541360 DOI: 10.1021/Acsmedchemlett.7B00458  0.356
2018 Musharrafieh R, Ma C, Wang J. Profiling the in vitro drug-resistance mechanism of influenza A viruses towards the AM2-S31N proton channel blockers. Antiviral Research. PMID 29518414 DOI: 10.1016/J.Antiviral.2018.03.002  0.355
2018 Wang Y, Hu Y, Xu S, Zhang Y, Musharrafieh R, Hau RK, Ma C, Wang J. In Vitro Pharmacokinetic Optimizations of AM2-S31N Channel Blockers Led to the Discovery of Slow-Binding Inhibitors with Potent Antiviral Activity against Drug-Resistant Influenza A Viruses. Journal of Medicinal Chemistry. PMID 29341607 DOI: 10.1021/Acs.Jmedchem.7B01536  0.372
2018 Lee S, Musharrafieh R, Xu X, Struts AV, Wang J, Molugu TR, Brown MF. Solid-State 2 H NMR Investigations of Viral M2 Ion Channel Drugs Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1549  0.328
2017 Ma C, Wang J. Functional studies reveal the similarities and differences between AM2 and BM2 proton channels from influenza viruses. Biochimica Et Biophysica Acta. PMID 29106970 DOI: 10.1016/J.Bbamem.2017.10.026  0.338
2017 Williams JK, Shcherbakov AA, Wang J, Hong M. Protonation equilibria and pore-opening structure of the dual-histidine influenza B virus M2 transmembrane proton channel from solid-state NMR. The Journal of Biological Chemistry. PMID 28893910 DOI: 10.1074/Jbc.M117.813998  0.368
2017 Hu Y, Zhang J, Musharrafieh R, Hau R, Ma C, Wang J. Chemical Genomics Approach Leads to the Identification of Hesperadin, an Aurora B Kinase Inhibitor, as a Broad-Spectrum Influenza Antiviral. International Journal of Molecular Sciences. 18. PMID 28885544 DOI: 10.3390/Ijms18091929  0.341
2017 Hu Y, Zhang J, Musharrafieh RG, Ma C, Hau R, Wang J. Discovery of dapivirine, a nonnucleoside HIV-1 reverse transcriptase inhibitor, as a broad-spectrum antiviral against both influenza A and B viruses. Antiviral Research. PMID 28778830 DOI: 10.1016/J.Antiviral.2017.07.016  0.341
2017 Gou Y, Zhang Y, Zhang Z, Wang J, Zhou Z, Liang H, Yang F. Design of an anticancer copper(II) pro-drug based on the Lys199 residue of the active targeting human serum albumin nanoparticle carrier. Molecular Pharmaceutics. PMID 28471669 DOI: 10.1021/acs.molpharmaceut.6b01074  0.334
2017 Hu Y, Wang Y, Li F, Ma C, Wang J. Design and expeditious synthesis of organosilanes as potent antivirals targeting multidrug-resistant influenza A viruses. European Journal of Medicinal Chemistry. 135: 70-76. PMID 28433777 DOI: 10.1016/J.Ejmech.2017.04.038  0.349
2017 Barniol-Xicota M, Gazzarrini S, Torres E, Hu Y, Wang J, Naesens L, Moroni A, Vazquez S. Slow but steady wins the race: dissimilarities among new dual inhibitors of the wild-type and the V27A mutant M2 channels of influenza A virus. Journal of Medicinal Chemistry. PMID 28418242 DOI: 10.1021/Acs.Jmedchem.6B01758  0.375
2017 Hu Y, Sneyd H, Dekant R, Wang J. Influenza A Virus Nucleoprotein: A Highly Conserved Multi-Functional Viral Protein As A Hot Antiviral Drug Target. Current Topics in Medicinal Chemistry. PMID 28240183 DOI: 10.2174/1568026617666170224122508  0.343
2017 Drakopoulos A, Tzitzoglaki C, Ma C, Freudenberger K, Hoffmann A, Hu Y, Gauglitz G, Schmidtke M, Wang J, Kolocouris A. Affinity of Rimantadine Enantiomers against Influenza A/M2 Protein Revisited. Acs Medicinal Chemistry Letters. 8: 145-150. PMID 28217261 DOI: 10.1021/Acsmedchemlett.6B00311  0.343
2017 Li F, Hu Y, Wang Y, Ma C, Wang J. Expeditious Lead Optimization of Isoxazole-Containing Influenza A Virus M2-S31N Inhibitors Using the Suzuki-Miyaura Cross-Coupling Reaction. Journal of Medicinal Chemistry. PMID 28182419 DOI: 10.1021/Acs.Jmedchem.6B01852  0.359
2017 Liu Y, Zhou LJ, Wang J, Li D, Ren WJ, Peng J, Wei X, Xu T, Xin WJ, Pang RP, Li YY, Qin ZH, Murugan M, Mattson MP, Wu LJ, et al. TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 871-881. PMID 28123022 DOI: 10.1523/Jneurosci.2235-16.2016  0.306
2017 Hu Y, Musharrafieh R, Ma C, Zhang J, Smee DF, DeGrado WF, Wang J. An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses. Antiviral Research. PMID 28087313 DOI: 10.1016/J.Antiviral.2017.01.006  0.674
2016 Liu Y, Zhou LJ, Wang J, Li D, Ren WJ, Peng J, Wei X, Xu T, Xin WJ, Pang RP, Li YY, Qin ZH, Murugan M, Mattson MP, Wu LJ, et al. TNF-α differentially regulates synaptic plasticity in the hippocampus and spinal cord by microglia-dependent mechanisms after peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27998892 DOI: 10.1523/JNEUROSCI.2235-16.2016  0.307
2016 Nguyen TT, Tsoh JY, Woo K, Stewart SL, Le GM, Burke A, Gildengorin G, Pasick RJ, Wang J, Chan E, Fung LC, Jih J, McPhee SJ. Colorectal Cancer Screening and Chinese Americans: Efficacy of Lay Health Worker Outreach and Print Materials. American Journal of Preventive Medicine. PMID 27986352 DOI: 10.1016/j.amepre.2016.10.003  0.541
2016 Li F, Ma C, Hu Y, Wang Y, Wang J. Discovery of Potent Antivirals against Amantadine-Resistant Influenza A Viruses by Targeting the M2-S31N Proton Channel. Acs Infectious Diseases. PMID 27657178 DOI: 10.1021/Acsinfecdis.6B00130  0.379
2016 Gou Y, Wang J, Chen S, Zhang Z, Zhang Y, Zhang W, Yang F. α-N-heterocyclic thiosemicarbazone Fe(III) complex: Characterization of its antitumor activity and identification of anticancer mechanism. European Journal of Medicinal Chemistry. 123: 354-364. PMID 27487566 DOI: 10.1016/j.ejmech.2016.07.041  0.328
2016 Ma C, Li F, Musharrafieh R, Wang J. Discovery of cyclosporine A and its analogs as broad-spectrum anti-influenza drugs with a high in vitro genetic barrier of drug resistance. Antiviral Research. PMID 27478032 DOI: 10.1016/J.Antiviral.2016.07.019  0.356
2016 Qi J, Zhang Y, Gou Y, Lee P, Wang J, Chen S, Zhou Z, Wu X, Yang F, Liang H. Multidrug Delivery Systems Based on Human Serum Albumin for Combination Therapy With 3 Anticancer Agents. Molecular Pharmaceutics. PMID 27453125 DOI: 10.1021/Acs.Molpharmaceut.6B00277  0.378
2016 Ma C, Zhang J, Wang J. Pharmacological characterizations of the spectrum of antiviral activity and genetic barrier of drug resistance of M2-S31N channel blockers. Molecular Pharmacology. PMID 27385729 DOI: 10.1124/Mol.116.105346  0.369
2016 Williams JK, Tietze D, Lee M, Wang J, Hong M. Solid-State NMR Investigation of the Conformation, Proton Conduction, and Hydration of the Influenza B Virus M2 Transmembrane Proton Channel. Journal of the American Chemical Society. PMID 27286559 DOI: 10.1021/Jacs.6B03142  0.352
2016 Yue S, Wu L, Wang J, Tang Y, Qu C, Shi X, Zhang P, Ge Y, Cao Y, Pang H, Shan C, Cui X, Qian L, Duan JA. Metabolic profile of anhydrosafflor yellow B in rats by ultra-fast liquid chromatography/quadrupole time-of-flight mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1014: 37-44. PMID 26871281 DOI: 10.1016/j.jchromb.2016.01.047  0.515
2016 Li F, Ma C, DeGrado WF, Wang J. Discovery of highly potent inhibitors targeting the predominant drug-resistant S31N mutant of the influenza A virus M2 proton channel. Journal of Medicinal Chemistry. PMID 26771709 DOI: 10.1021/Acs.Jmedchem.5B01910  0.672
2016 Tsoh JY, Sentell T, Gildengorin G, Le GM, Chan E, Fung LC, Pasick RJ, Stewart S, Wong C, Woo K, Burke A, Wang J, McPhee SJ, Nguyen TT. Healthcare Communication Barriers and Self-Rated Health in Older Chinese American Immigrants. Journal of Community Health. PMID 26746205 DOI: 10.1007/S10900-015-0148-4  0.519
2016 Wang J. M2 as a target to combat influenza drug resistance: what does the evidence say? Future Virology. 11: 1-4. DOI: 10.2217/Fvl.15.95  0.376
2016 Musharrafieh R, Chawla U, Zheng W, Kaung L, Perera SM, Knowles T, Huang A, Pitman MC, Wang J, Liang H, Brown MF. Computational and Experimental Studies of Lipid-Protein Interactions in Biomemrane Function Biophysical Journal. 110: 257a. DOI: 10.1016/J.Bpj.2015.11.1411  0.303
2015 Wu Y, Wang J, Zeng F, Huang S, Huang J, Xie H, Yu C, Wu S. Pyrene derivative emitting red or near-infrared light with monomer/excimer conversion and its application to ratiometric detection of hypochlorite. Acs Applied Materials & Interfaces. PMID 26701212 DOI: 10.1021/Acsami.5B11023  0.609
2015 Zhu Q, Song X, Zhou J, Wang Y, Xia J, Qian W, Zhu J, Gao R, Wang J, Xiao H. Target of HIV-1 Envelope Glycoprotein gp120-Induced Hippocampal Neuron Damage: Role of Voltage-Gated K(+) Channel Kv2.1. Viral Immunology. PMID 26393286 DOI: 10.1089/Vim.2015.0020  0.392
2015 Wu Y, Huang S, Zeng F, Wang J, Yu C, Huang J, Xie H, Wu S. A ratiometric fluorescent system for carboxylesterase detection with AIE dots as FRET donors. Chemical Communications (Cambridge, England). PMID 26165151 DOI: 10.1039/C5Cc04771D  0.597
2015 Li F, Ma C, Wang J. Inhibitors targeting the influenza virus hemagglutinin. Current Medicinal Chemistry. 22: 1361-82. PMID 25723505 DOI: 10.2174/0929867322666150227153919  0.359
2015 Wang J, Li F, Ma C. Recent Progress in Designing Inhibitors That Target the Drug-resistant M2 Proton Channels from the Influenza A Viruses. Biopolymers. PMID 25663018 DOI: 10.1002/Bip.22623  0.361
2014 Wu Y, Canturk B, Jo H, Ma C, Gianti E, Klein ML, Pinto LH, Lamb RA, Fiorin G, Wang J, DeGrado WF. Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel. Journal of the American Chemical Society. 136: 17987-95. PMID 25470189 DOI: 10.1021/Ja508461M  0.679
2014 Ghosh A, Wang J, Moroz YS, Korendovych IV, Zanni M, DeGrado WF, Gai F, Hochstrasser RM. 2D IR spectroscopy reveals the role of water in the binding of channel-blocking drugs to the influenza M2 channel. The Journal of Chemical Physics. 140: 235105. PMID 24952572 DOI: 10.1063/1.4881188  0.76
2014 Montalvo GL, Zhang Y, Young TM, Costanzo MJ, Freeman KB, Wang J, Clements DJ, Magavern E, Kavash RW, Scott RW, Liu D, Degrado WF. De novo design of self-assembling foldamers that inhibit heparin-protein interactions. Acs Chemical Biology. 9: 967-75. PMID 24491145 DOI: 10.1021/Cb500026X  0.737
2014 Wang J, Wu Y, DeGrado WF. Structure and Inhibition of the M2 Proton Channel from the Influenza a Virus Biophysical Journal. 106: 549a. DOI: 10.1016/J.Bpj.2013.11.3060  0.691
2013 Wu C, Huang R, Chen J, Gu Q, Zhu B, Wang J, Zhang K, Chen Q, Xiong C, Liu Y, Li J, Zhou YH, Ding Y. Avian influenza A(H7N9) virus screening in patients with fever and flu-like symptoms in a tertiary hospital in an area with confirmed cases. Plos One. 8: e82613. PMID 24367529 DOI: 10.1371/journal.pone.0082613  0.46
2013 Rey-Carrizo M, Torres E, Ma C, Barniol-Xicota M, Wang J, Wu Y, Naesens L, DeGrado WF, Lamb RA, Pinto LH, Vázquez S. 3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant. Journal of Medicinal Chemistry. 56: 9265-74. PMID 24237039 DOI: 10.1021/Jm401340P  0.666
2013 Ma C, Fiorin G, Carnevale V, Wang J, Lamb RA, Klein ML, Wu Y, Pinto LH, DeGrado WF. Asp44 stabilizes the Trp41 gate of the M2 proton channel of influenza A virus. Structure (London, England : 1993). 21: 2033-41. PMID 24139991 DOI: 10.1016/J.Str.2013.08.029  0.643
2013 Wang J, Qian W, Zhu Q, Chen J, Huan F, Gao R, Xiao H. Martentoxin, a large-conductance Ca(2+)-activated K(+) channel inhibitor, attenuated TNF-α-induced nitric oxide release by human umbilical vein endothelial cells. Journal of Biomedical Research. 27: 386-93. PMID 24086172 DOI: 10.7555/Jbr.27.20120080  0.384
2013 Schmidt NW, Mishra A, Wang J, DeGrado WF, Wong GC. Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission. Journal of the American Chemical Society. 135: 13710-9. PMID 23962302 DOI: 10.1021/Ja400146Z  0.63
2013 Williams JK, Tietze D, Wang J, Wu Y, DeGrado WF, Hong M. Drug-induced conformational and dynamical changes of the S31N mutant of the influenza M2 proton channel investigated by solid-state NMR. Journal of the American Chemical Society. 135: 9885-97. PMID 23758317 DOI: 10.1021/Ja4041412  0.67
2013 Liu H, Lu Y, Liu Q, Huo X, Peng B, Ren D, Wu D, Wang J, Wang X, Tang Z, Liu W, Meng F. Comparison of pyrethroid resistance in adults and larvae of Culex pipiens pallens (Diptera: Culicidae) from four field populations in China. Journal of Economic Entomology. 106: 360-5. PMID 23448052  0.327
2013 Wang J, Ma C, Wang J, Jo H, Canturk B, Fiorin G, Pinto LH, Lamb RA, Klein ML, DeGrado WF. Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus. Journal of Medicinal Chemistry. 56: 2804-12. PMID 23437766 DOI: 10.1021/Jm301538E  0.676
2013 Balgi AD, Wang J, Cheng DY, Ma C, Pfeifer TA, Shimizu Y, Anderson HJ, Pinto LH, Lamb RA, DeGrado WF, Roberge M. Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay. Plos One. 8: e55271. PMID 23383318 DOI: 10.1371/Journal.Pone.0055271  0.692
2013 Mao L, Wang J, DeGrado WF, Inouye M. An assay suitable for high throughput screening of anti-influenza drugs. Plos One. 8: e54070. PMID 23326573 DOI: 10.1371/Journal.Pone.0054070  0.682
2013 Wang J, Wu Y, Ma C, Fiorin G, Wang J, Pinto LH, Lamb RA, Klein ML, Degrado WF. Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus. Proceedings of the National Academy of Sciences of the United States of America. 110: 1315-20. PMID 23302696 DOI: 10.1073/Pnas.1216526110  0.689
2013 Thomaston JL, Nguyen PA, Brown EC, Upshur MA, Wang J, DeGrado WF, Howard KP. Detection of drug-induced conformational change of a transmembrane protein in lipid bilayers using site-directed spin labeling. Protein Science : a Publication of the Protein Society. 22: 65-73. PMID 23139077 DOI: 10.1002/Pro.2186  0.622
2013 Wu Y, Wang J, DeGrado W. Solution NMR structure of the influenza A virus S31N mutant (19-49) in presence of drug M2WJ332 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Ly0/Pdb  0.618
2012 Wang J, Chen F, Zheng P, Deng W, Yuan J, Peng B, Wang R, Liu W, Zhao H, Wang Y, Wu G. Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice. Experimental Neurology. 236: 79-87. PMID 22524989 DOI: 10.1016/j.expneurol.2012.03.024  0.329
2012 Fiorin G, Carnevale V, Wang J, Ma C, Wang T, Hu F, Lamb R, Pinto L, Hong M, DeGrado W, Klein M. Mapping Water Density to Design New Blockers Against a Viral Proton Channel Biophysical Journal. 102: 682a. DOI: 10.1016/J.Bpj.2011.11.3708  0.658
2011 Wang J, Ma C, Wu Y, Lamb RA, Pinto LH, DeGrado WF. Exploring organosilane amines as potent inhibitors and structural probes of influenza a virus M2 proton channel. Journal of the American Chemical Society. 133: 13844-7. PMID 21819109 DOI: 10.1021/Ja2050666  0.691
2011 Wang J, Ma C, Fiorin G, Carnevale V, Wang T, Hu F, Lamb RA, Pinto LH, Hong M, Klein ML, DeGrado WF. Molecular dynamics simulation directed rational design of inhibitors targeting drug-resistant mutants of influenza A virus M2. Journal of the American Chemical Society. 133: 12834-41. PMID 21744829 DOI: 10.1021/Ja204969M  0.676
2011 Wang J, Ma C, Balannik V, Pinto LH, Lamb RA, Degrado WF. Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. Acs Medicinal Chemistry Letters. 2: 307-312. PMID 21691418 DOI: 10.1021/Ml100297W  0.685
2011 Duque MD, Ma C, Torres E, Wang J, Naesens L, Juárez-Jiménez J, Camps P, Luque FJ, DeGrado WF, Lamb RA, Pinto LH, Vázquez S. Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus. Journal of Medicinal Chemistry. 54: 2646-57. PMID 21466220 DOI: 10.1021/Jm101334Y  0.672
2011 Rogers JM, Polishchuk AL, Guo L, Wang J, DeGrado WF, Gai F. Photoinduced electron transfer and fluorophore motion as a probe of the conformational dynamics of membrane proteins: application to the influenza a M2 proton channel. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 3815-21. PMID 21401044 DOI: 10.1021/La200480D  0.732
2011 Cady SD, Wang J, Wu Y, DeGrado WF, Hong M. Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. Journal of the American Chemical Society. 133: 4274-84. PMID 21381693 DOI: 10.1021/Ja102581N  0.663
2011 Wang J, Qiu JX, Soto C, DeGrado WF. Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus. Current Opinion in Structural Biology. 21: 68-80. PMID 21247754 DOI: 10.1016/J.Sbi.2010.12.002  0.664
2010 Leiding T, Wang J, Martinsson J, DeGrado WF, Arsköld SP. Proton and cation transport activity of the M2 proton channel from influenza A virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 15409-14. PMID 20713739 DOI: 10.1073/Pnas.1009997107  0.612
2010 Cady SD, Schmidt-Rohr K, Wang J, Soto CS, Degrado WF, Hong M. Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature. 463: 689-92. PMID 20130653 DOI: 10.1038/Nature08722  0.676
2010 Balannik V, Obrdlik P, Inayat S, Steensen C, Wang J, Rausch JM, DeGrado WF, Kelety B, Pinto LH. Solid-supported membrane technology for the investigation of the influenza A virus M2 channel activity. PflüGers Archiv : European Journal of Physiology. 459: 593-605. PMID 19946785 DOI: 10.1007/S00424-009-0760-1  0.679
2010 Cady S, Schmidt-Rohr K, Wang J, Soto C, DeGrado W, Hong M. Solid-state NMR structure of the M2 transmembrane peptide of the influenza A virus in DMPC lipid bilayers bound to deuterated amantadine Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Kqt/Pdb  0.614
2009 Balannik V, Wang J, Ohigashi Y, Jing X, Magavern E, Lamb RA, Degrado WF, Pinto LH. Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus. Biochemistry. 48: 11872-82. PMID 19905033 DOI: 10.1021/Bi9014488  0.687
2009 Wang J, Cady SD, Balannik V, Pinto LH, DeGrado WF, Hong M. Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus. Journal of the American Chemical Society. 131: 8066-76. PMID 19469531 DOI: 10.1021/Ja900063S  0.676
2009 Balannik V, Steensen C, Obrdlik P, Kelety B, Wang J, DeGrado WF, Pinto LH. Reversibility of Amantadine Inhibition in the M2 Proton Channel of Influenza A Virus Biophysical Journal. 96: 668a. DOI: 10.1016/J.Bpj.2008.12.3531  0.663
2007 Uttamchandani M, Lee WL, Wang J, Yao SQ. Quantitative inhibitor fingerprinting of metalloproteases using small molecule microarrays. Journal of the American Chemical Society. 129: 13110-7. PMID 17915867 DOI: 10.1021/Ja073914V  0.716
2007 Uttamchandani M, Wang J, Li J, Hu M, Sun H, Chen KY, Liu K, Yao SQ. Inhibitor fingerprinting of matrix metalloproteases using a combinatorial peptide hydroxamate library. Journal of the American Chemical Society. 129: 7848-58. PMID 17539636 DOI: 10.1021/Ja070870H  0.765
2006 Wang J, Uttamchandani M, Li J, Hu M, Yao SQ. "Click" synthesis of small molecule probes for activity-based fingerprinting of matrix metalloproteases. Chemical Communications (Cambridge, England). 3783-5. PMID 16969456 DOI: 10.1039/B609446E  0.746
2006 Wang J, Uttamchandani M, Li J, Hu M, Yao SQ. Rapid assembly of matrix metalloprotease inhibitors using click chemistry. Organic Letters. 8: 3821-4. PMID 16898826 DOI: 10.1021/Ol061431A  0.76
2006 Uttamchandani M, Wang J, Yao SQ. Protein and small molecule microarrays: powerful tools for high-throughput proteomics. Molecular Biosystems. 2: 58-68. PMID 16880923 DOI: 10.1039/B513935J  0.698
2006 Sun H, Chattopadhaya S, Wang J, Yao SQ. Recent developments in microarray-based enzyme assays: from functional annotation to substrate/inhibitor fingerprinting. Analytical and Bioanalytical Chemistry. 386: 416-26. PMID 16791553 DOI: 10.1007/S00216-006-0511-5  0.63
2006 Wang J, Uttamchandani M, Sun LP, Yao SQ. Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays. Chemical Communications (Cambridge, England). 717-9. PMID 16465317 DOI: 10.1039/B515278J  0.711
2006 Wang J, Uttamchandani M, Sun H, Yao SQ. Small molecule microarrays: Applications using specially tagged chemical libraries Qsar and Combinatorial Science. 25: 1009-1019. DOI: 10.1002/Qsar.200640083  0.747
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