Year |
Citation |
Score |
2024 |
Cheung-Lee WL, Kolev JN, McIntosh JA, Gil AA, Pan W, Xiao L, Velásquez JE, Gangam R, Winston MS, Li S, Abe K, Alwedi E, Dance ZEX, Fan H, Hiraga K, et al. Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan. Angewandte Chemie (International Ed. in English). e202316133. PMID 38279624 DOI: 10.1002/anie.202316133 |
0.402 |
|
2020 |
Steck V, Kolev JN, Ren X, Fasan R. Mechanism-Guided Design and Discovery of Efficient P450-Derived C-H Amination Biocatalysts. Journal of the American Chemical Society. PMID 32407077 DOI: 10.1021/Jacs.9B12859 |
0.48 |
|
2019 |
Huffman MA, Fryszkowska A, Alvizo O, Borra-Garske M, Campos KR, Canada KA, Devine PN, Duan D, Forstater JH, Grosser ST, Halsey HM, Hughes GJ, Jo J, Joyce LA, Kolev JN, et al. Design of an in vitro biocatalytic cascade for the manufacture of islatravir. Science (New York, N.Y.). 366: 1255-1259. PMID 31806816 DOI: 10.1126/Science.Aay8484 |
0.344 |
|
2015 |
Singh R, Kolev JN, Sutera PA, Fasan R. Enzymatic C(sp(3))-H Amination: P450-Catalyzed Conversion of Carbonazidates into Oxazolidinones. Acs Catalysis. 5: 1685-1691. PMID 25954592 DOI: 10.1021/Cs5018612 |
0.667 |
|
2014 |
Kolev JN, Zaengle JM, Ravikumar R, Fasan R. Enhancing the efficiency and regioselectivity of P450 oxidation catalysts by unnatural amino acid mutagenesis. Chembiochem : a European Journal of Chemical Biology. 15: 1001-10. PMID 24692265 DOI: 10.1002/Cbic.201400060 |
0.601 |
|
2014 |
Kolev JN, O'Dwyer KM, Jordan CT, Fasan R. Discovery of potent parthenolide-based antileukemic agents enabled by late-stage P450-mediated C-H functionalization. Acs Chemical Biology. 9: 164-73. PMID 24206617 DOI: 10.1021/Cb400626W |
0.715 |
|
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