Year |
Citation |
Score |
2021 |
Ray AM, Salim N, Stevens M, Chitre S, Abdeen S, Washburn A, Sivinski J, O'Hagan HM, Chapman E, Johnson SM. Exploiting the HSP60/10 chaperonin system as a chemotherapeutic target for colorectal cancer. Bioorganic & Medicinal Chemistry. 40: 116129. PMID 33971488 DOI: 10.1016/j.bmc.2021.116129 |
0.697 |
|
2019 |
Washburn A, Abdeen S, Ovechkina Y, Ray AM, Stevens M, Chitre S, Sivinski J, Park Y, Johnson J, Hoang QQ, Chapman E, Parish T, Johnson SM. Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections. Bioorganic & Medicinal Chemistry Letters. PMID 31047750 DOI: 10.1016/J.Bmcl.2019.04.034 |
0.353 |
|
2019 |
Stevens M, Abdeen S, Salim N, Ray AM, Washburn A, Chitre S, Sivinski J, Park Y, Hoang QQ, Chapman E, Johnson SM. HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules. Bioorganic & Medicinal Chemistry Letters. PMID 30852084 DOI: 10.1016/J.Bmcl.2019.02.028 |
0.735 |
|
2018 |
Kunkle T, Abdeen S, Salim N, Ray AM, Stevens M, Ambrose AJ, Victorino J, Park Y, Hoang QQ, Chapman E, Johnson SM. Hydroxybiphenylamide GroEL/ES inhibitors are potent antibacterials against planktonic and biofilm forms of Staphylococcus aureus. Journal of Medicinal Chemistry. PMID 30392371 DOI: 10.1021/Acs.Jmedchem.8B01293 |
0.745 |
|
2018 |
Abdeen S, Kunkle T, Salim N, Ray AM, Mammadova N, Summers C, Stevens M, Ambrose A, Park Y, Schultz PG, Horwich AL, Hoang Q, Chapman E, Johnson SM. Sulfonamido-2-arylbenzoxazole GroEL/ES inhibitors are potent antibacterials against methicillin-resistant Staphylococcus aureus (MRSA). Journal of Medicinal Chemistry. PMID 30060666 DOI: 10.1021/Acs.Jmedchem.8B00989 |
0.744 |
|
2016 |
Abdeen S, Salim N, Mammadova N, Summers CM, Goldsmith-Pestana K, McMahon-Pratt D, Schultz PG, Horwich AL, Chapman E, Johnson SM. Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness. Bioorganic & Medicinal Chemistry Letters. PMID 27720295 DOI: 10.1016/J.Bmcl.2016.09.051 |
0.728 |
|
2016 |
Abdeen S, Salim N, Mammadova N, Summers CM, Frankson R, Ambrose AJ, Anderson GG, Schultz PG, Horwich AL, Chapman E, Johnson SM. GroEL/ES inhibitors as potential antibiotics. Bioorganic & Medicinal Chemistry Letters. 26: 3127-34. PMID 27184767 DOI: 10.1016/J.Bmcl.2016.04.089 |
0.759 |
|
2010 |
Abdeen SJ, Swett RJ, Feig AL. Peptide inhibitors targeting Clostridium difficile toxins A and B. Acs Chemical Biology. 5: 1097-103. PMID 20863124 DOI: 10.1021/Cb100209B |
0.667 |
|
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