Year |
Citation |
Score |
2021 |
Heinrich S, Grote M, Sievers S, Kushnir S, Schulz F. Polyether Cyclization Cascade Alterations in Response to Monensin Polyketide Synthase Mutations. Chembiochem : a European Journal of Chemical Biology. PMID 34729883 DOI: 10.1002/cbic.202100584 |
0.312 |
|
2019 |
Grote M, Kushnir S, Pryk N, Möller D, Erver J, Ismail-Ali A, Schulz F. Identification of crucial bottlenecks in engineered polyketide biosynthesis. Organic & Biomolecular Chemistry. PMID 31090778 DOI: 10.1039/C9Ob00831D |
0.322 |
|
2019 |
Grote M, Schulz F. Exploring the Promiscuous Enzymatic Activation of Non-natural Polyketide Extender Units In Vitro and In Vivo for Monensin Biosynthesis. Chembiochem : a European Journal of Chemical Biology. PMID 30629783 DOI: 10.1002/Cbic.201800734 |
0.43 |
|
2018 |
Schulz F, Dirkmann M, Nowack J. An in vitro Biosynthesis of Sesquiterpenes starting from Acetic Acid. Chembiochem : a European Journal of Chemical Biology. PMID 30085399 DOI: 10.1002/Cbic.201800128 |
0.372 |
|
2018 |
Möller D, Kushnir S, Grote M, Ismail-Ali A, Koopmans KRM, Calo F, Heinrich S, Diehl B, Schulz F. Flexible Enzymatic Activation of Artificial Polyketide Extender Units by Streptomyces cinnamonensis into the Monensin Biosynthetic Pathway. Letters in Applied Microbiology. PMID 29927502 DOI: 10.1111/Lam.13039 |
0.374 |
|
2018 |
Ismail-Ali A, Fansa EK, Pryk N, Yahiaoui S, Kushnir S, Pflieger M, Wittinghofer A, Schulz F. Biosynthesis-driven structure-activity relationship study of premonensin-derivatives. Organic & Biomolecular Chemistry. 14: 7671-5. PMID 27452503 DOI: 10.1039/C6Ob01201A |
0.333 |
|
2017 |
Schulz F, Dirkmann M, Iglesias J, Muñoz V, Sokkar P, Rumancev C, von Gundlach A, Krenczyk O, Vöpel T, Nowack J, Schroer MA, Ebbinghaus S, Herrmann C, Rosenhahn A, Sanchez-Garcia E. A multi-perspective approach to solvent regulation of enzymatic activity: HMG-CoA reductase. Chembiochem : a European Journal of Chemical Biology. PMID 29139594 DOI: 10.1002/Cbic.201700596 |
0.35 |
|
2017 |
Ganguly A, Luong TQ, Brylski O, Dirkmann M, Möller D, Ebbinghaus S, Schulz F, Winter R, Sanchez-Garcia E, Thiel W. Elucidation of the Catalytic Mechanism of a Miniature Zinc Finger Hydrolase. The Journal of Physical Chemistry. B. PMID 28648071 DOI: 10.1021/Acs.Jpcb.7B05027 |
0.329 |
|
2015 |
Klopries S, Bravo-Rodriguez K, Koopmans KR, Sundermann U, Yahiaoui S, Arens J, Kushnir S, Sanchez-Garcia E, Schulz F. Data in support of substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis. Data in Brief. 5: 528-36. PMID 26587559 DOI: 10.1016/J.Dib.2015.09.052 |
0.375 |
|
2015 |
Bravo-Rodriguez K, Klopries S, Koopmans KR, Sundermann U, Yahiaoui S, Arens J, Kushnir S, Schulz F, Sanchez-Garcia E. Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. Chemistry & Biology. 22: 1425-30. PMID 26526102 DOI: 10.1016/J.Chembiol.2015.02.008 |
0.418 |
|
2015 |
Pryk N, Schulz F. Chemical biology: biosynthetic interceptors. Nature Chemistry. 7: 102-4. PMID 25615663 DOI: 10.1038/Nchem.2168 |
0.366 |
|
2014 |
Arens J, Bergs D, Mewes M, Merz J, Schembecker G, Schulz F. Heterologous fermentation of a diterpene from Alternaria brassisicola. Mycology. 5: 207-219. PMID 25379342 DOI: 10.1080/21501203.2014.917735 |
0.314 |
|
2014 |
Bravo-Rodriguez K, Ismail-Ali AF, Klopries S, Kushnir S, Ismail S, Fansa EK, Wittinghofer A, Schulz F, Sanchez-Garcia E. Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivatives. Chembiochem : a European Journal of Chemical Biology. 15: 1991-7. PMID 25044264 DOI: 10.1002/Cbic.201402206 |
0.378 |
|
2013 |
Klopries S, Sundermann U, Schulz F. Quantification of N-acetylcysteamine activated methylmalonate incorporation into polyketide biosynthesis. Beilstein Journal of Organic Chemistry. 9: 664-74. PMID 23616811 DOI: 10.3762/Bjoc.9.75 |
0.404 |
|
2013 |
Sundermann U, Bravo-Rodriguez K, Klopries S, Kushnir S, Gomez H, Sanchez-Garcia E, Schulz F. Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. Acs Chemical Biology. 8: 443-50. PMID 23181268 DOI: 10.1021/Cb300505W |
0.43 |
|
2011 |
Kwan DH, Schulz F. The stereochemistry of complex polyketide biosynthesis by modular polyketide synthases. Molecules (Basel, Switzerland). 16: 6092-115. PMID 21775938 DOI: 10.3390/Molecules16076092 |
0.676 |
|
2011 |
Kwan DH, Tosin M, Schläger N, Schulz F, Leadlay PF. Insights into the stereospecificity of ketoreduction in a modular polyketide synthase. Organic & Biomolecular Chemistry. 9: 2053-6. PMID 21340070 DOI: 10.1039/C1Ob00022E |
0.684 |
|
2009 |
Zilly FE, Taglieber A, Schulz F, Hollmann F, Reetz MT. Deazaflavins as mediators in light-driven cytochrome P450 catalyzed hydroxylations. Chemical Communications (Cambridge, England). 7152-4. PMID 19921013 DOI: 10.1039/B913863C |
0.683 |
|
2008 |
Kwan DH, Sun Y, Schulz F, Hong H, Popovic B, Sim-Stark JC, Haydock SF, Leadlay PF. Prediction and manipulation of the stereochemistry of enoylreduction in modular polyketide synthases. Chemistry & Biology. 15: 1231-40. PMID 19022183 DOI: 10.1016/J.Chembiol.2008.09.012 |
0.668 |
|
2008 |
Taglieber A, Schulz F, Hollman F, Rusek M, Reetz MT. Light-driven biocatalytic oxidation and reduction reactions: Scope and limitations Chembiochem. 9: 565-572. PMID 18288667 DOI: 10.1002/Cbic.200700435 |
0.541 |
|
2007 |
Hollmann F, Taglieber A, Schulz F, Reetz MT. A light-driven stereoselective biocatalytic oxidation Angewandte Chemie - International Edition. 46: 2903-2906. PMID 17352446 DOI: 10.1002/Anie.200605169 |
0.565 |
|
2006 |
Mihovilovic MD, Rudroff F, Winninger A, Schneider T, Schulz F, Reetz MT. Microbial Baeyer-Villiger oxidation: stereopreference and substrate acceptance of cyclohexanone monooxygenase mutants prepared by directed evolution. Organic Letters. 8: 1221-4. PMID 16524308 DOI: 10.1021/Ol0601040 |
0.513 |
|
2005 |
Schulz F, Leca F, Hollmann F, Reetz MT. Towards practical biocatalytic Baeyer-Villiger reactions: applying a thermostable enzyme in the gram-scale synthesis of optically-active lactones in a two-liquid-phase system. Beilstein Journal of Organic Chemistry. 1: 10. PMID 16542025 DOI: 10.1186/1860-5397-1-10 |
0.616 |
|
2005 |
Bocola M, Schulz F, Leca F, Vogel A, Fraaije MW, Reetz MT. Converting phenylacetone monooxygenase into phenylcyclohexanone monooxygenase by rational design: Towards practical Baeyer-Villiger monooxygenases Advanced Synthesis and Catalysis. 347: 979-986. DOI: 10.1002/Adsc.200505069 |
0.477 |
|
2004 |
Reetz MT, Brunner B, Schneider T, Schulz F, Clouthier CM, Kayser MM. Directed evolution as a method to create enantioselective cyclohexanone monooxygenases for catalysis in Baeyer-Villiger reactions. Angewandte Chemie (International Ed. in English). 43: 4075-8. PMID 15300699 DOI: 10.1002/Anie.200460272 |
0.435 |
|
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