Michael Thomas McManus - Publications

University of California, San Francisco, San Francisco, CA 
Noncoding RNA, Genetics, Molecular Biology

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Xie SQ, Leeke BJ, Whilding C, Wagner RT, Garcia-Llagostera F, Low Y, Chammas P, Cheung NT, Dormann D, McManus MT, Percharde M. Nucleolar-based repression is essential for embryonic two-cell stage exit. Genes & Development. 36: 331-347. PMID 35273077 DOI: 10.1101/gad.349172.121  0.788
2020 Covarrubias S, Vollmers AC, Capili A, Boettcher M, Shulkin A, Correa MR, Halasz H, Robinson EK, O'Briain L, Vollmers C, Blau J, Katzman S, McManus MT, Carpenter S. High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways. Cell Reports. 33: 108541. PMID 33378675 DOI: 10.1016/j.celrep.2020.108541  0.758
2020 Bouchareychas L, Duong P, Covarrubias S, Alsop E, Phu TA, Chung A, Gomes M, Wong D, Meechoovet B, Capili A, Yamamoto R, Nakauchi H, McManus MT, Carpenter S, Van Keuren-Jensen K, et al. Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo. Cell Reports. 32: 107881. PMID 32668250 DOI: 10.1016/J.Celrep.2020.107881  0.575
2020 Tromp AT, Van Gent M, Jansen JP, Scheepmaker LM, Velthuizen A, De Haas CJC, Van Kessel KPM, Bardoel BW, Boettcher M, McManus MT, Van Strijp JAG, Lebbink RJ, Haas PA, Spaan AN. Host-Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity. Toxins. 12. PMID 32041354 DOI: 10.3390/Toxins12020106  0.746
2019 Gagnon JD, Kageyama R, Shehata HM, Fassett MS, Mar DJ, Wigton EJ, Johansson K, Litterman AJ, Odorizzi P, Simeonov D, Laidlaw BJ, Panduro M, Patel S, Jeker LT, Feeney ME, ... McManus MT, et al. miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival. Cell Reports. 28: 2169-2181.e4. PMID 31433990 DOI: 10.1016/J.Celrep.2019.07.064  0.359
2019 Lindtner S, Catta-Preta R, Tian H, Su-Feher L, Price JD, Dickel DE, Greiner V, Silberberg SN, McKinsey GL, McManus MT, Pennacchio LA, Visel A, Nord AS, Rubenstein JLR. Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons. Cell Reports. 28: 2048-2063.e8. PMID 31433982 DOI: 10.1016/J.Celrep.2019.07.022  0.365
2019 Mues M, Karra L, Romero-Moya D, Wandler A, Hangauer MJ, Ksionda O, Thus Y, Lindenbergh M, Shannon K, McManus MT, Roose JP. High-Complexity shRNA Libraries and PI3 Kinase Inhibition in Cancer: High-Fidelity Synthetic Lethality Predictions. Cell Reports. 27: 631-647.e5. PMID 30970263 DOI: 10.1016/J.Celrep.2019.03.045  0.727
2019 Das S, Ansel KM, Bitzer M, Breakefield XO, Charest A, Galas DJ, Gerstein MB, Gupta M, Milosavljevic A, McManus MT, Patel T, Raffai RL, Rozowsky J, Roth ME, et al. The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research. Cell. 177: 231-242. PMID 30951667 DOI: 10.1016/J.Cell.2019.03.023  0.338
2019 Boettcher M, Covarrubias S, Biton A, Blau J, Wang H, Zaitlen N, McManus MT. Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding. Bmc Genomics. 20: 107. PMID 30727954 DOI: 10.1186/S12864-019-5480-0  0.773
2018 Elling R, Robinson EK, Shapleigh B, Liapis SC, Covarrubias S, Katzman S, Groff AF, Jiang Z, Agarwal S, Motwani M, Chan J, Sharma S, Hennessy EJ, FitzGerald GA, McManus MT, et al. Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2. Cell Reports. 25: 1511-1524.e6. PMID 30404006 DOI: 10.1016/J.Celrep.2018.10.027  0.793
2018 Lu Y, Cao J, Napoli M, Xia Z, Zhao N, Creighton CJ, Li W, Chen X, Flores ER, McManus MT, Rosen JM. MiR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential during Mammary Reconstitution. Stem Cells (Dayton, Ohio). PMID 30267595 DOI: 10.1002/Stem.2914  0.346
2018 Tromp AT, Van Gent M, Abrial P, Martin A, Jansen JP, De Haas CJC, Van Kessel KPM, Bardoel BW, Kruse E, Bourdonnay E, Boettcher M, McManus MT, Day CJ, Jennings MP, Lina G, et al. Publisher Correction: Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin. Nature Microbiology. PMID 30177744 DOI: 10.1038/S41564-018-0247-Y  0.715
2018 Lee J, Pappalardo Z, Chopra DG, Hennings TG, Vaughn I, Lan C, Choe JJ, Ang K, Chen S, Arkin M, McManus MT, German MS, Ku GM. A genetic interaction map of insulin production identifies Mfi as an inhibitor of mitochondrial fission. Endocrinology. PMID 30059978 DOI: 10.1210/En.2018-00426  0.755
2018 Zhou J, Hunter DA, Lewis DH, McManus MT, Zhang H. Insights into carotenoid accumulation using VIGS to block different steps of carotenoid biosynthesis in petals of California poppy. Plant Cell Reports. PMID 29922849 DOI: 10.1007/S00299-018-2314-5  0.353
2018 Tromp AT, Van Gent M, Abrial P, Martin A, Jansen JP, De Haas CJC, Van Kessel KPM, Bardoel BW, Kruse E, Bourdonnay E, Boettcher M, McManus MT, Day CJ, Jennings MP, Lina G, et al. Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin. Nature Microbiology. PMID 29736038 DOI: 10.1038/S41564-018-0159-X  0.586
2018 Shang W, Jiang Y, Boettcher M, Ding K, Mollenauer M, Liu Z, Wen X, Liu C, Hao P, Zhao S, McManus MT, Wei L, Weiss A, Wang H. Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29632189 DOI: 10.1073/Pnas.1801340115  0.684
2018 Bulut-Karslioglu A, Macrae TA, Oses-Prieto JA, Covarrubias S, Percharde M, Ku G, Diaz A, McManus MT, Burlingame AL, Ramalho-Santos M. The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output. Cell Stem Cell. 22: 369-383.e8. PMID 29499153 DOI: 10.1016/J.Stem.2018.02.004  0.794
2018 Jee D, Yang JS, Park SM, Farmer DT, Wen J, Chou T, Chow A, McManus MT, Kharas MG, Lai EC. Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals. Molecular Cell. 69: 265-278.e6. PMID 29351846 DOI: 10.1016/J.Molcel.2017.12.027  0.781
2018 Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT. Dual gene activation and knockout screen reveals directional dependencies in genetic networks. Nature Biotechnology. PMID 29334369 DOI: 10.1038/Nbt.4062  0.777
2018 Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT. Abstract B098: GPX4 is a broadly shared gene vulnerability among residual tumors Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B098  0.716
2017 Hangauer MJ, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition. Nature. PMID 29088702 DOI: 10.1038/Nature24297  0.722
2017 Covarrubias S, Robinson EK, Shapleigh B, Vollmers A, Katzman S, Hanley N, Fong N, McManus MT, Carpenter S. CRISPR/Cas9-based screening of long noncoding RNAs (lncRNAs) in macrophages with an NF-kappa B reporter. The Journal of Biological Chemistry. PMID 29051223 DOI: 10.1074/Jbc.M117.799155  0.79
2017 Farmer D, Nathan S, Finley J, Yu KS, Emmerson E, Byrnes L, Sneddon J, McManus M, Tward A, Knox S. Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland. Development (Cambridge, England). PMID 28576768 DOI: 10.1242/Dev.150789  0.786
2017 Farmer DT, Finley JK, Chen FY, Tarifeño-Saldivia E, McNamara NA, Knox SM, McManus MT. miR-205 is a critical regulator of lacrimal gland development. Developmental Biology. PMID 28511845 DOI: 10.1016/J.Ydbio.2017.05.012  0.792
2017 Pappalardo Z, Chopra DG, Hennings TG, Richards H, Choe J, Yang K, Baeyens L, Ang K, Chen S, Arkin M, German MS, McManus MT, Ku GM. A Whole Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response. Diabetes. PMID 28246293 DOI: 10.2337/Db16-0962  0.788
2017 Farmer DT, McManus MT. MicroRNAs in ectodermal appendages. Current Opinion in Genetics & Development. 43: 61-66. PMID 28103525 DOI: 10.1016/J.Gde.2016.12.006  0.799
2016 Inoue F, Kircher M, Martin B, Cooper GM, Witten DM, McManus MT, Ahituv N, Shendure J. A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity. Genome Research. PMID 27831498 DOI: 10.1101/Gr.212092.116  0.301
2016 Roldan MB, Islam A, Dinh PT, Leung S, McManus MT. Phosphate availability regulates ethylene biosynthesis gene expression and protein accumulation in white clover ( Trifolium repens L) roots. Bioscience Reports. PMID 27737923 DOI: 10.1042/Bsr20160148  0.302
2016 Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW, Powers S, Smith K, Aburi M, Iavarone A, Lasorella A, ... ... McManus MT, et al. Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Molecular Cancer Research : McR. PMID 27401613 DOI: 10.1158/1541-7786.Mcr-16-0090  0.767
2016 Pua HH, Steiner DF, Patel S, Gonzalez JR, Ortiz-Carpena JF, Kageyama R, Chiou NT, Gallman A, de Kouchkovsky D, Jeker LT, McManus MT, Erle DJ, Ansel KM. MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production. Immunity. PMID 26850657 DOI: 10.1016/J.Immuni.2016.01.003  0.379
2016 Horiuchi D, Zhou AY, Corella AN, Yau C, Balakrishnan S, Kessenbrock K, Lawson DA, Camarda R, Anderton BN, Bazarov AV, Eyob H, Rohrberg J, Yaswen P, McManus MT, Rugo HS, et al. Abstract B34: PIM kinase as a novel therapeutic target for triple-negative breast cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-B34  0.313
2016 Mues M, Lindenbergh MF, McManus MT, Roose JP. Abstract B22: Screening and validation of combination therapy in T cell leukemia Cancer Research. 76. DOI: 10.1158/1538-7445.Fbcr15-B22  0.315
2015 Islam A, Leung S, Burgess EP, Laing WA, Richardson KA, Hofmann RW, Dijkwel PP, McManus MT. Knock-down of transcript abundance of a family of Kunitz proteinase inhibitor genes in white clover (Trifolium repens) reveals a redundancy and diversity of gene function. The New Phytologist. 208: 1188-1201. PMID 26377591 DOI: 10.1111/Nph.13543  0.369
2015 Patton JG, Franklin JL, Weaver AM, Vickers K, Zhang B, Coffey RJ, Ansel KM, Blelloch R, Goga A, Huang B, L'Etoille N, Raffai RL, Lai CP, Krichevsky AM, Mateescu B, ... ... McManus MT, et al. Biogenesis, delivery, and function of extracellular RNA. Journal of Extracellular Vesicles. 4: 27494. PMID 26320939 DOI: 10.3402/Jev.V4.27494  0.373
2015 Khan IS, Park CY, Mavropoulos A, Shariat N, Pollack JL, Barczak AJ, Erle DJ, McManus MT, Anderson MS, Jeker LT. Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells. Plos One. 10: e0135440. PMID 26270036 DOI: 10.1371/Journal.Pone.0135440  0.719
2015 Boettcher M, McManus MT. Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR Molecular Cell. 58: 575-585. PMID 26000843 DOI: 10.1016/J.Molcel.2015.04.028  0.602
2015 Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, ... ... McManus MT, et al. Integrative analysis of 111 reference human epigenomes. Nature. 518: 317-30. PMID 25693563 DOI: 10.1038/Nature14248  0.338
2015 Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, Delaney A, Tam A, Kamoh B, Cho S, Griffith M, Chu A, Robertson G, Cheung D, Li I, ... ... McManus MT, et al. Epigenetic and transcriptional determinants of the human breast. Nature Communications. 6: 6351. PMID 25690954 DOI: 10.1038/Ncomms7351  0.744
2015 Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H. A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver. Hepatology (Baltimore, Md.). 61: 141-52. PMID 25131933 DOI: 10.1002/Hep.27379  0.339
2014 Qin H, Diaz A, Blouin L, Lebbink RJ, Patena W, Tanbun P, LeProust EM, McManus MT, Song JS, Ramalho-Santos M. Systematic identification of barriers to human iPSC generation. Cell. 158: 449-61. PMID 25036638 DOI: 10.1016/J.Cell.2014.05.040  0.704
2014 Hangauer MJ, Carpenter S, McManus MT. Discovering the complexity of the metazoan transcriptome. Genome Biology. 15: 112. PMID 25001157 DOI: 10.1186/Gb4172  0.786
2014 van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nature Communications. 5: 3832. PMID 24807418 DOI: 10.1038/Ncomms4832  0.765
2014 Morris JP, Greer R, Russ HA, von Figura G, Kim GE, Busch A, Lee J, Hertel KJ, Kim S, McManus M, Hebrok M. Dicer regulates differentiation and viability during mouse pancreatic cancer initiation. Plos One. 9: e95486. PMID 24788257 DOI: 10.1371/Journal.Pone.0095486  0.317
2014 Zhao W, Pollack JL, Blagev DP, Zaitlen N, McManus MT, Erle DJ. Massively parallel functional annotation of 3' untranslated regions. Nature Biotechnology. 32: 387-91. PMID 24633241 DOI: 10.1038/Nbt.2851  0.323
2014 Wang H, Flach H, Onizawa M, Wei L, McManus MT, Weiss A. Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210. Nature Immunology. 15: 393-401. PMID 24608041 DOI: 10.1038/Ni.2846  0.493
2014 Horiuchi D, Zhou AY, Corella AN, Yau C, Lawson DA, Bazarov AV, Yaswen P, McManus MT, Werb Z, Welm AL, Goga A. Abstract LB-122: PIM1 kinase inhibition halts the growth of MYC-overexpressing triple-negative breast tumors Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-122  0.32
2013 Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chemistry & Biology. 20: 1352-63. PMID 24183972 DOI: 10.1016/J.Chembiol.2013.09.014  0.691
2013 Farmer DT, Shariat N, Park CY, Liu HJ, Mavropoulos A, McManus MT. Partially penetrant postnatal lethality of an epithelial specific MicroRNA in a mouse knockout. Plos One. 8: e76634. PMID 24116130 DOI: 10.1371/Journal.Pone.0076634  0.788
2013 Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA. The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development (Cambridge, England). 140: 3348-59. PMID 23863486 DOI: 10.1242/Dev.089193  0.315
2013 Hangauer MJ, Vaughn IW, McManus MT. Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. Plos Genetics. 9: e1003569. PMID 23818866 DOI: 10.1371/Journal.Pgen.1003569  0.8
2013 Blau JA, McManus MT. Renewable RNAi. Nature Biotechnology. 31: 319-20. PMID 23563428 DOI: 10.1038/nbt.2547  0.769
2013 Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 152: 909-22. PMID 23394947 DOI: 10.1016/J.Cell.2013.01.030  0.784
2013 Bronevetsky Y, Villarino AV, Eisley CJ, Barbeau R, Barczak AJ, Heinz GA, Kremmer E, Heissmeyer V, McManus MT, Erle DJ, Rao A, Ansel KM. T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire. The Journal of Experimental Medicine. 210: 417-32. PMID 23382546 DOI: 10.1084/Jem.20111717  0.349
2013 Wei MC, Matheny CJ, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley D, Rau RE, Brown P, McManus MT, Weissman JS, Cleary ML. Next-Generation NAMPT Inhibitors For ALL Identified By Sequential High-Throughput Phenotypic Chemical and Functional Genomic Screens Blood. 122: 171-171. DOI: 10.1182/Blood.V122.21.171.171  0.708
2013 Horiuchi D, Zhou AY, Corella AN, Yau C, Lawson DA, Bazarov AV, Yaswen P, McManus MT, Welm AL, Werb Z, Goga A. Abstract B232: PIM1 kinase is essential for the growth of MYC-overexpressing triple-negative breast tumors and is an efficacious therapeutic target. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B232  0.308
2012 Upton JP, Wang L, Han D, Wang ES, Huskey NE, Lim L, Truitt M, McManus MT, Ruggero D, Goga A, Papa FR, Oakes SA. IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. Science (New York, N.Y.). 338: 818-22. PMID 23042294 DOI: 10.1126/Science.1226191  0.327
2012 Ku GM, Kim H, Vaughn IW, Hangauer MJ, Myung Oh C, German MS, McManus MT. Research resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome. Molecular Endocrinology (Baltimore, Md.). 26: 1783-92. PMID 22915829 DOI: 10.1210/Me.2012-1176  0.775
2012 Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M. Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. Plos Genetics. 8: e1002823. PMID 22844247 DOI: 10.1371/Journal.Pgen.1002823  0.381
2012 Dallas A, Ilves H, Ge Q, Kumar P, Shorenstein J, Kazakov SA, Cuellar TL, McManus MT, Behlke MA, Johnston BH. Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing. Nucleic Acids Research. 40: 9255-71. PMID 22810205 DOI: 10.1093/Nar/Gks662  0.742
2012 Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, Richards H, Li Z, Adler D, Yoshinaga Y, Martinez M, Nefadov M, Abbas AK, Weiss A, Lanier LL, ... ... McManus MT, et al. A resource for the conditional ablation of microRNAs in the mouse. Cell Reports. 1: 385-91. PMID 22570807 DOI: 10.1016/J.Celrep.2012.02.008  0.492
2012 Liu X, Jin DY, McManus MT, Mourelatos Z. Precursor microRNA-programmed silencing complex assembly pathways in mammals. Molecular Cell. 46: 507-17. PMID 22503104 DOI: 10.1016/J.Molcel.2012.03.010  0.316
2012 Choi YS, Patena W, Leavitt AD, McManus MT. Widespread RNA 3'-end oligouridylation in mammals. Rna (New York, N.Y.). 18: 394-401. PMID 22291204 DOI: 10.1261/Rna.029306.111  0.6
2012 Ku GM, Pappalardo Z, Luo CC, German MS, McManus MT. An siRNA screen in pancreatic beta cells reveals a role for Gpr27 in insulin production. Plos Genetics. 8: e1002449. PMID 22253604 DOI: 10.1371/Journal.Pgen.1002449  0.72
2011 Lebbink RJ, Lowe M, Chan T, Khine H, Wang X, McManus MT. Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs. Plos One. 6: e26213. PMID 22031824 DOI: 10.1371/Journal.Pone.0026213  0.698
2011 Zhang Z, O'Rourke JR, McManus MT, Lewandoski M, Harfe BD, Sun X. The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning Developmental Biology. 351: 254-265. PMID 21256124 DOI: 10.1016/J.Ydbio.2011.01.005  0.351
2010 Park CY, Choi YS, McManus MT. Analysis of microRNA knockouts in mice. Human Molecular Genetics. 19: R169-75. PMID 20805106 DOI: 10.1093/Hmg/Ddq367  0.594
2010 Dugas JC, Cuellar TL, Scholze A, Ason B, Ibrahim A, Emery B, Zamanian JL, Foo LC, McManus MT, Barres BA. Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron. 65: 597-611. PMID 20223197 DOI: 10.1016/J.Neuron.2010.01.027  0.741
2010 Scott RW, Yoo SD, Hunter DA, Gong D, Chen B, Leung S, McManus MT. Regulation of 1-aminocyclopropane-1-carboxylate oxidase gene expression during leaf ontogeny in white clover Plant Growth Regulation. 62: 31-41. DOI: 10.1007/S10725-010-9480-Y  0.304
2009 Shin D, Shin JY, McManus MT, Ptácek LJ, Fu YH. Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Annals of Neurology. 66: 843-57. PMID 20035504 DOI: 10.1002/Ana.21927  0.324
2009 Tan GS, Garchow BG, Liu X, Yeung J, Morris JP, Cuellar TL, McManus MT, Kiriakidou M. Expanded RNA-binding activities of mammalian Argonaute 2. Nucleic Acids Research. 37: 7533-45. PMID 19808937 DOI: 10.1093/Nar/Gkp812  0.761
2009 Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A, Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature. 460: 863-8. PMID 19587682 DOI: 10.1038/Nature08212  0.301
2009 Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nature Methods. 6: 443-5. PMID 19448642 DOI: 10.1038/Nmeth.1330  0.793
2009 Ruggiero T, Trabucchi M, De Santa F, Zupo S, Harfe BD, McManus MT, Rosenfeld MG, Briata P, Gherzi R. LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2898-908. PMID 19423639 DOI: 10.1096/Fj.09-131342  0.339
2009 Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A, Horiuchi D, Lebbink RJ, Mo YY, Goga A, McManus MT. Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. The Journal of Biological Chemistry. 284: 18515-24. PMID 19419954 DOI: 10.1074/Jbc.M109.006676  0.731
2009 Soukup GA, Fritzsch B, Pierce ML, Weston MD, Jahan I, McManus MT, Harfe BD. Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice. Developmental Biology. 328: 328-41. PMID 19389351 DOI: 10.1016/J.Ydbio.2009.01.037  0.354
2009 Sekine S, Ogawa R, Ito R, Hiraoka N, McManus MT, Kanai Y, Hebrok M. Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis. Gastroenterology. 136: 2304-2315.e1-4. PMID 19272382 DOI: 10.1053/J.Gastro.2009.02.067  0.332
2009 Pastorelli LM, Wells S, Fray M, Smith A, Hough T, Harfe BD, McManus MT, Smith L, Woolf AS, Cheeseman M, Greenfield A. Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 140-51. PMID 19169742 DOI: 10.1007/S00335-008-9169-Y  0.351
2009 Papaioannou MD, Pitetti JL, Ro S, Park C, Aubry F, Schaad O, Vejnar CE, Kühne F, Descombes P, Zdobnov EM, McManus MT, Guillou F, Harfe BD, Yan W, Jégou B, et al. Sertoli cell Dicer is essential for spermatogenesis in mice. Developmental Biology. 326: 250-9. PMID 19071104 DOI: 10.1016/J.Ydbio.2008.11.011  0.408
2008 Harvey SJ, Jarad G, Cunningham J, Goldberg S, Schermer B, Harfe BD, McManus MT, Benzing T, Miner JH. Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. Journal of the American Society of Nephrology : Jasn. 19: 2150-8. PMID 18776121 DOI: 10.1681/Asn.2008020233  0.352
2008 Zhou X, Jeker LT, Fife BT, Zhu S, Anderson MS, McManus MT, Bluestone JA. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. The Journal of Experimental Medicine. 205: 1983-91. PMID 18725525 DOI: 10.1084/Jem.20080707  0.329
2008 Maatouk DM, Loveland KL, McManus MT, Moore K, Harfe BD. Dicer1 is required for differentiation of the mouse male germline. Biology of Reproduction. 79: 696-703. PMID 18633141 DOI: 10.1095/Biolreprod.108.067827  0.366
2008 Reid JG, Nagaraja AK, Lynn FC, Drabek RB, Muzny DM, Shaw CA, Weiss MK, Naghavi AO, Khan M, Zhu H, Tennakoon J, Gunaratne GH, Corry DB, Miller J, McManus MT, et al. Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes. Genome Research. 18: 1571-81. PMID 18614752 DOI: 10.1101/Gr.078246.108  0.391
2008 Damiani D, Alexander JJ, O'Rourke JR, McManus M, Jadhav AP, Cepko CL, Hauswirth WW, Harfe BD, Strettoi E. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4878-87. PMID 18463241 DOI: 10.1523/Jneurosci.0828-08.2008  0.546
2008 Davis TH, Cuellar TL, Koch SM, Barker AJ, Harfe BD, McManus MT, Ullian EM. Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4322-30. PMID 18434510 DOI: 10.1523/Jneurosci.4815-07.2008  0.781
2008 Cuellar TL, Davis TH, Nelson PT, Loeb GB, Harfe BD, Ullian E, McManus MT. Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 105: 5614-9. PMID 18385371 DOI: 10.1073/Pnas.0801689105  0.777
2008 Osokine I, Hsu R, Loeb GB, McManus MT. Unintentional miRNA ablation is a risk factor in gene knockout studies: a short report. Plos Genetics. 4: e34. PMID 18282110 DOI: 10.1371/Journal.Pgen.0040034  0.576
2008 Ku G, McManus MT. Behind the scenes of a small RNA gene-silencing pathway. Human Gene Therapy. 19: 17-26. PMID 18211225 DOI: 10.1089/Hum.2007.1226  0.755
2008 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz HR, Schier AF, Dulac C. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 57: 41-55. PMID 18184563 DOI: 10.1016/J.Neuron.2007.11.018  0.314
2008 McManus MT. Further examination of abscission zone cells as ethylene target cells in higher plants Annals of Botany. 101: 285-292. PMID 17965027 DOI: 10.1093/Aob/Mcm269  0.318
2007 Crittenden JR, Heidersbach A, McManus MT. Lentiviral strategies for RNAi knockdown of neuronal genes. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.26. PMID 18428658 DOI: 10.1002/0471142301.Ns0526S39  0.4
2007 O'Rourke JR, Georges SA, Seay HR, Tapscott SJ, McManus MT, Goldhamer DJ, Swanson MS, Harfe BD. Essential role for Dicer during skeletal muscle development. Developmental Biology. 311: 359-68. PMID 17936265 DOI: 10.1016/J.Ydbio.2007.08.032  0.332
2007 Lynn FC, Skewes-Cox P, Kosaka Y, McManus MT, Harfe BD, German MS. MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes. 56: 2938-45. PMID 17804764 DOI: 10.2337/Db07-0175  0.383
2007 Nawroth R, van Zante A, Cervantes S, McManus M, Hebrok M, Rosen SD. Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells. Plos One. 2: e392. PMID 17460759 DOI: 10.1371/Journal.Pone.0000392  0.317
2007 Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell. 129: 303-17. PMID 17397913 DOI: 10.1016/J.Cell.2007.03.030  0.364
2007 Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, Zhang M, McManus MT, Gertler FB, Scott ML, Van Parijs L. Erratum: Corrigendum: A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference Nature Genetics. 39: 803-803. DOI: 10.1038/Ng0607-803  0.401
2006 Harper RW, Xu C, McManus M, Heidersbach A, Eiserich JP. Duox2 exhibits potent heme peroxidase activity in human respiratory tract epithelium. Febs Letters. 580: 5150-4. PMID 16970942 DOI: 10.1016/J.Febslet.2006.08.048  0.323
2006 Heidersbach A, Gaspar-Maia A, McManus MT, Ramalho-Santos M. RNA interference in embryonic stem cells and the prospects for future therapies. Gene Therapy. 13: 478-86. PMID 16520820 DOI: 10.1038/Sj.Gt.3302723  0.325
2006 Harris KS, Zhang Z, McManus MT, Harfe BD, Sun X. Dicer function is essential for lung epithelium morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 2208-13. PMID 16452165 DOI: 10.1073/PNAS.0510839103  0.309
2005 Gapper NE, Coupe SA, McKenzie MJ, Scott RW, Christey MC, Lill RE, McManus MT, Jameson PE. Senescence-associated down-regulation of 1-aminocyclopropane-1-carboxylate (ACC) oxidase delays harvest-induced senescence in broccoli. Functional Plant Biology : Fpb. 32: 891-901. PMID 32689185 DOI: 10.1071/Fp05076  0.348
2005 Cuellar TL, McManus MT. MicroRNAs and endocrine biology. The Journal of Endocrinology. 187: 327-32. PMID 16423811 DOI: 10.1677/Joe.1.06426  0.779
2005 Hornstein E, Mansfield JH, Yekta S, Hu JK, Harfe BD, McManus MT, Baskerville S, Bartel DP, Tabin CJ. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature. 438: 671-4. PMID 16319892 DOI: 10.1038/Nature04138  0.371
2005 Morris JP, McManus MT. Slowing down the Ras lane: miRNAs as tumor suppressors? Science's Stke : Signal Transduction Knowledge Environment. 2005: pe41. PMID 16107327 DOI: 10.1126/Stke.2972005Pe41  0.329
2005 Hong JH, Hwang ES, McManus MT, Amsterdam A, Tian Y, Kalmukova R, Mueller E, Benjamin T, Spiegelman BM, Sharp PA, Hopkins N, Yaffe MB. TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science (New York, N.Y.). 309: 1074-8. PMID 16099986 DOI: 10.1126/Science.1110955  0.53
2005 Harfe BD, McManus MT, Mansfield JH, Hornstein E, Tabin CJ. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proceedings of the National Academy of Sciences of the United States of America. 102: 10898-903. PMID 16040801 DOI: 10.1073/Pnas.0504834102  0.373
2004 McManus MT. Small RNAs and Immunity Immunity. 21: 747-756. PMID 15589164 DOI: 10.1016/J.Immuni.2004.11.007  0.385
2004 Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A, Farzan-Kashani R, Zuker M, Pasquinelli AE, Ruvkun G, Sharp PA, Tabin CJ, McManus MT. MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nature Genetics. 36: 1079-83. PMID 15361871 DOI: 10.1038/Ng1421  0.523
2004 Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, Van Parijs L, Jaenisch R, Jacks T. Cre-lox-regulated conditional RNA interference from transgenes. Proceedings of the National Academy of Sciences of the United States of America. 101: 10380-5. PMID 15240889 DOI: 10.1073/Pnas.0403954101  0.539
2003 McManus MT. MicroRNAs and cancer Seminars in Cancer Biology. 13: 253-258. PMID 14563119 DOI: 10.1016/S1044-579X(03)00038-5  0.376
2003 Ge Q, McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, Chen J. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proceedings of the National Academy of Sciences of the United States of America. 100: 2718-23. PMID 12594334 DOI: 10.1073/Pnas.0437841100  0.514
2003 Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, Rooney DL, Zhang M, Ihrig MM, McManus MT, Gertler FB, Scott ML, Van Parijs L. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nature Genetics. 33: 401-6. PMID 12590264 DOI: 10.1038/Ng1117  0.44
2002 McManus MT, Haines BB, Dillon CP, Whitehurst CE, van Parijs L, Chen J, Sharp PA. Small interfering RNA-mediated gene silencing in T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 169: 5754-60. PMID 12421955 DOI: 10.4049/Jimmunol.169.10.5754  0.57
2002 Chen Z, Indjeian VB, McManus M, Wang L, Dynlacht BD. CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells. Developmental Cell. 3: 339-50. PMID 12361598 DOI: 10.1016/S1534-5807(02)00258-7  0.336
2002 McManus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nature Reviews. Genetics. 3: 737-47. PMID 12360232 DOI: 10.1038/Nrg908  0.565
2002 McManus MT, Petersen CP, Haines BB, Chen J, Sharp PA. Gene silencing using micro-RNA designed hairpins. Rna (New York, N.Y.). 8: 842-50. PMID 12088155 DOI: 10.1017/S1355838202024032  0.565
2001 McManus MT, Shimamura M, Grams J, Hajduk SL. Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei. Rna (New York, N.Y.). 7: 167-75. PMID 11233974 DOI: 10.1017/S1355838201002072  0.769
2000 Grams J, McManus MT, Hajduk SL. Processing of polycistronic guide RNAs is associated with RNA editing complexes in Trypanosoma brucei. The Embo Journal. 19: 5525-32. PMID 11032819 DOI: 10.1093/Emboj/19.20.5525  0.765
2000 McManus MT, Adler BK, Pollard VW, Hajduk SL. Trypanosoma brucei guide RNA poly(U) tail formation is stabilized by cognate mRNA. Molecular and Cellular Biology. 20: 883-91. PMID 10629045 DOI: 10.1128/Mcb.20.3.883-891.2000  0.627
1998 Sabatini RS, Adler BK, Madison-Antenucci S, McManus MT, Hajduk SL. Biochemical methods for analysis of kinetoplastid RNA editing. Methods (San Diego, Calif.). 15: 15-26. PMID 9614649 DOI: 10.1006/Meth.1998.0602  0.621
1998 McManus MT, Thompson DS, Merriman C, Lyne L, Osborne DJ. Transdifferentiation of mature cortical cells to functional abscission cells in bean Plant Physiology. 116: 891-9. PMID 9501122 DOI: 10.1104/Pp.116.3.891  0.303
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