Brent R. Copp - Publications

Affiliations: 
The University of Auckland, Auckland, Auckland, New Zealand 
Area:
Marine natural products

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Cadelis MM, Geese S, Uy BB, Mulholland DR, van de Pas SJ, Grey A, Weir BS, Copp BR, Wiles S. Antimicrobial Metabolites against Methicillin-Resistant from the Endophytic Fungus . Molecules (Basel, Switzerland). 26. PMID 33669637 DOI: 10.3390/molecules26041094  0.68
2021 Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 33570537 DOI: 10.1039/d0np00089b  0.56
2020 Lee AJ, Cadelis MM, Kim SH, Swift S, Copp BR, Villas-Boas SG. Epipyrone A, a Broad-Spectrum Antifungal Compound Produced by ICMP 19927. Molecules (Basel, Switzerland). 25. PMID 33352899 DOI: 10.3390/molecules25245997  0.68
2020 Cadelis MM, Copp BR, Wiles S. A Review of Fungal Protoilludane Sesquiterpenoid Natural Products. Antibiotics (Basel, Switzerland). 9. PMID 33352728 DOI: 10.3390/antibiotics9120928  0.68
2020 Cadelis MM, Geese S, Gris L, Weir BS, Copp BR, Wiles S. A Revised Structure and Assigned Absolute Configuration of Theissenolactone A. Molecules (Basel, Switzerland). 25. PMID 33092217 DOI: 10.3390/molecules25204823  0.68
2020 Cadelis MM, Li SA, Bourguet-Kondracki ML, Blanchet M, Douafer H, Brunel JM, Copp B. Spermine derivatives of indole-3-carboxylic acid, indole-3-acetic acid and indole-3-acrylic acid as Gram-negative antibiotic adjuvants. Chemmedchem. PMID 33090655 DOI: 10.1002/cmdc.202000359  0.68
2020 Lam CFC, Cadelis MM, Copp BR. Exploration of the Electrophilic Reactivity of the Cytotoxic Marine Alkaloid Discorhabdin C and Subsequent Discovery of a New Dimeric C-1/N-13-Linked Discorhabdin Natural Product. Marine Drugs. 18. PMID 32752009 DOI: 10.3390/md18080404  0.68
2020 Barker D, Lee S, Varnava KG, Sparrow K, van Rensburg M, Deed RC, Cadelis MM, Li SA, Copp BR, Sarojini V, Pilkington LI. Synthesis and Antibacterial Analysis of Analogues of the Marine Alkaloid Pseudoceratidine. Molecules (Basel, Switzerland). 25. PMID 32545320 DOI: 10.3390/molecules25112713  0.68
2020 Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 32025684 DOI: 10.1039/c9np00069k  0.56
2019 Cadelis MM, Pike EIW, Kang W, Wu Z, Bourguet-Kondracki ML, Blanchet M, Vidal N, Brunel JM, Copp BR. Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines. European Journal of Medicinal Chemistry. 183: 111708. PMID 31550659 DOI: 10.1016/j.ejmech.2019.111708  0.68
2019 Pearce AN, Hill CAE, Page MJ, Keyzers RA, Copp BR. An Acetylenic Lipid from the New Zealand Ascidian : Exemplification of an Improved Workflow for Determination of Absolute Configuration of Long-Chain 2-Amino-3-alkanols. Journal of Natural Products. PMID 31356078 DOI: 10.1021/acs.jnatprod.9b00504  1
2019 Li SA, Cadelis MM, Sue K, Blanchet M, Vidal N, Brunel JM, Bourguet-Kondracki ML, Copp BR. 6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers. Bioorganic & Medicinal Chemistry. PMID 30975502 DOI: 10.1016/j.bmc.2019.04.004  0.68
2019 Molinski TF, Salib MN, Pearce AN, Copp BR. The Configuration of Distaminolyne A is S: Quantitative Evaluation of Exciton Coupling Circular Dichroism of N, O- Bis-arenoyl-1-amino-2-alkanols. Journal of Natural Products. PMID 30958674 DOI: 10.1021/acs.jnatprod.8b00937  1
2019 Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 30663727 DOI: 10.1039/c8np00092a  0.56
2018 Pearce AN, Copp BR, Molinski TF. Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols. Molecules (Basel, Switzerland). 24. PMID 30591663 DOI: 10.3390/molecules24010090  1
2018 Cadelis MM, Copp BR. Investigation of the electrophilic reactivity of the biologically active marine sesquiterpenoid onchidal and model compounds. Beilstein Journal of Organic Chemistry. 14: 2229-2235. PMID 30202476 DOI: 10.3762/bjoc.14.197  0.68
2018 Harris EM, Strope JD, Beedie SL, Huang PA, Goey AKL, Cook KM, Schofield CJ, Chau CH, Cadelis MM, Copp BR, Gustafson KR, Figg WD. Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models. Marine Drugs. 16. PMID 30029505 DOI: 10.3390/Md16070241  0.68
2018 Blunt JW, Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 29335692 DOI: 10.1039/c7np00052a  0.56
2017 Pearce AN, Kaiser M, Copp BR. Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates. European Journal of Medicinal Chemistry. 140: 595-603. PMID 28988153 DOI: 10.1016/j.ejmech.2017.09.040  1
2017 Davidson SJ, Pearce AN, Copp BR, Barker D. Total Synthesis of (-)-Bicubebin A, B, (+)-Bicubebin C and Structural Reassignment of (-)-cis-Cubebin. Organic Letters. PMID 28901148 DOI: 10.1021/acs.orglett.7b02644  1
2017 Tempone AG, Ferreira DD, Lima ML, Costa Silva TA, Borborema SET, Reimão JQ, Galuppo MK, Guerra JM, Russell AJ, Wynne GM, Lai RYL, Cadelis MM, Copp BR. Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi. European Journal of Medicinal Chemistry. 139: 947-960. PMID 28881289 DOI: 10.1016/j.ejmech.2017.08.055  0.68
2017 Cadelis MM, Bourguet-Kondracki ML, Dubois J, Kaiser M, Brunel JM, Barker D, Copp BR. Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase. Bioorganic & Medicinal Chemistry. PMID 28666857 DOI: 10.1016/j.bmc.2017.06.029  0.68
2017 Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 34: 235-294. PMID 28290569 DOI: 10.1039/c6np00124f  0.56
2016 Cadelis MM, Khalil IM, Harper JL, Shaw L, Dubois J, Valentin A, Bourguet-Kondracki ML, Barker D, Copp BR. Structure-activity relationships of bioactive marine natural products leading to the identification of more potent non-natural analogues - the meroterpenoids, thiaplidiaquinones A and B. Planta Medica. 81: S1-S381. PMID 27976307 DOI: 10.1055/s-0036-1596124  0.68
2016 Cadelis MM, Bourguet-Kondracki ML, Dubois J, Valentin A, Barker D, Copp BR. Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors. Bioorganic & Medicinal Chemistry. 24: 3102-7. PMID 27240468 DOI: 10.1016/j.bmc.2016.05.024  0.68
2016 Goey AK, Chau CH, Sissung TM, Cook KM, Venzon DJ, Castro A, Ransom TR, Henrich CJ, McKee TC, McMahon JB, Grkovic T, Cadelis MM, Copp BR, Gustafson KR, Figg WD. Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction. Journal of Natural Products. PMID 27140429 DOI: 10.1021/Acs.Jnatprod.5B00846  0.72
2016 Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 33: 382-431. PMID 26837534 DOI: 10.1039/c5np00156k  0.56
2015 Wang J, Pearce AN, Chan ST, Taylor RB, Page MJ, Valentin A, Bourguet-Kondracki ML, Dalton JP, Wiles S, Copp BR. Biologically Active Acetylenic Amino Alcohol and N-Hydroxylated 1,2,3,4-Tetrahydro-β-carboline Constituents of the New Zealand Ascidian Pseudodistoma opacum. Journal of Natural Products. PMID 26670413 DOI: 10.1021/acs.jnatprod.5b00770  0.72
2015 Yeung L, Pilkington LI, Cadelis MM, Copp BR, Barker D. Total synthesis of panicein A2. Beilstein Journal of Organic Chemistry. 11: 1991-6. PMID 26664619 DOI: 10.3762/bjoc.11.215  0.68
2015 Harper JL, Khalil IM, Shaw L, Bourguet-Kondracki ML, Dubois J, Valentin A, Barker D, Copp BR. Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B. Marine Drugs. 13: 5102-10. PMID 26266415 DOI: 10.3390/md13085102  0.72
2015 He F, Mai LH, Longeon A, Copp BR, Loaëc N, Bescond A, Meijer L, Bourguet-Kondracki ML. Novel Adociaquinone Derivatives from the Indonesian Sponge Xestospongia sp. Marine Drugs. 13: 2617-28. PMID 25927661 DOI: 10.3390/md13052617  0.72
2015 Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 32: 116-211. PMID 25620233 DOI: 10.1039/c4np00144c  0.56
2015 Wang J, Prinsep MR, Gordon DP, Page MJ, Copp BR. Isolation and stereospecific synthesis of janolusimide B from a New Zealand collection of the bryozoan Bugula flabellata. Journal of Natural Products. 78: 530-3. PMID 25494238 DOI: 10.1021/np500752y  0.72
2014 Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 31: 160-258. PMID 24389707 DOI: 10.1039/c3np70117d  0.56
2013 Lam CF, Pearce AN, Tan SH, Kaiser M, Copp BR. Discovery and evaluation of thiazinoquinones as anti-protozoal agents. Marine Drugs. 11: 3472-99. PMID 24022732 DOI: 10.3390/md11093472  1
2013 Liew LP, Pearce AN, Kaiser M, Copp BR. Synthesis and in vitro and in vivo evaluation of antimalarial polyamines. European Journal of Medicinal Chemistry. 69: 22-31. PMID 23995215 DOI: 10.1016/j.ejmech.2013.07.055  1
2013 Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 30: 237-323. PMID 23263727 DOI: 10.1039/c2np20112g  0.56
2012 Lam CF, Grkovic T, Pearce AN, Copp BR. Investigation of the electrophilic reactivity of the cytotoxic marine alkaloid discorhabdin B. Organic & Biomolecular Chemistry. 10: 3092-7. PMID 22395232 DOI: 10.1039/c2ob07090a  1
2012 Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 29: 144-222. PMID 22193773 DOI: 10.1039/c2np00090c  0.56
2012 Lam CFC, Giddens AC, Chand N, Webb VL, Copp BR. Semi-synthesis of bioactive fluorescent analogues of the cytotoxic marine alkaloid discorhabdin C Tetrahedron. 68: 3187-3194. DOI: 10.1016/j.tet.2012.02.052  0.72
2011 Chan ST, Pearce AN, Januario AH, Page MJ, Kaiser M, McLaughlin RJ, Harper JL, Webb VL, Barker D, Copp BR. Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum. The Journal of Organic Chemistry. 76: 9151-6. PMID 21958335 DOI: 10.1021/jo201654h  0.72
2011 Chan ST, Pearce AN, Page MJ, Kaiser M, Copp BR. Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum. Journal of Natural Products. 74: 1972-9. PMID 21846091 DOI: 10.1021/np200509g  1
2011 Finlayson R, Pearce AN, Page MJ, Kaiser M, Bourguet-Kondracki ML, Harper JL, Webb VL, Copp BR. Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp. Journal of Natural Products. 74: 888-92. PMID 21348447 DOI: 10.1021/np1008619  0.72
2011 Finlayson R, Brackovic A, Simon-Levert A, Banaigs B, O'Toole RF, Miller CH, Copp BR. Establishment of the absolute configuration of the bioactive marine alkaloid eudistomin X by stereospecific synthesis Tetrahedron Letters. 52: 837-840. DOI: 10.1016/j.tetlet.2010.12.052  0.72
2010 Grkovic T, Pearce AN, Munro MH, Blunt JW, Davies-Coleman MT, Copp BR. Isolation and characterization of diastereomers of discorhabdins H and K and assignment of absolute configuration to discorhabdins D, N, Q, S, T, and U. Journal of Natural Products. 73: 1686-93. PMID 20860391 DOI: 10.1021/np100443c  1
2009 Appleton DR, Chuen CS, Berridge MV, Webb VL, Copp BR. Rossinones A and B, biologically active meroterpenoids from the Antarctic ascidian, Aplidium species. The Journal of Organic Chemistry. 74: 9195-8. PMID 19863121 DOI: 10.1021/jo901846j  0.56
2008 Grkovic T, Ding Y, Li XC, Webb VL, Ferreira D, Copp BR. Enantiomeric discorhabdin alkaloids and establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra. The Journal of Organic Chemistry. 73: 9133-6. PMID 18855481 DOI: 10.1021/Jo801622N  0.56
2008 Chia EW, Pearce AN, Berridge MV, Larsen L, Perry NB, Sansom CE, Godfrey CA, Hanton LR, Lu GL, Walton M, Denny WA, Webb VL, Copp BR, Harper JL. Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis. Bioorganic & Medicinal Chemistry. 16: 9432-42. PMID 18835721 DOI: 10.1016/j.bmc.2008.09.052  0.72
2008 Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Harper JL, Webb VL, Copp BR. Orthidines A-E, tubastrine, 3,4-dimethoxyphenethyl-β-guanidine, and 1,14-sperminedihomovanillamide: potential anti-inflammatory alkaloids isolated from the New Zealand ascidian Aplidium orthium that act as inhibitors of neutrophil respiratory burst Tetrahedron. 64: 5748-5755. DOI: 10.1016/j.tet.2008.04.012  0.72
2008 Giddens AC, Nielsen L, Boshoff HI, Tasdemir D, Perozzo R, Kaiser M, Wang F, Sacchettini JC, Copp BR. Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities Tetrahedron. 64: 1242-1249. DOI: 10.1016/J.Tet.2007.11.075  0.72
2007 Lan CC, Laurenson S, Copp BR, Cattin PM, Love DR. Whole organism approaches to chemical genomics: the promising role of zebrafish (Danio rerio). Expert Opinion On Drug Discovery. 2: 1389-401. PMID 23484534 DOI: 10.1517/17460441.2.10.1389  0.72
2007 Pearce AN, Chia EW, Berridge MV, Clark GR, Harper JL, Larsen L, Maas EW, Page MJ, Perry NB, Webb VL, Copp BR. Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis. Journal of Natural Products. 70: 936-40. PMID 17497807 DOI: 10.1021/np060626o  0.72
2007 Copp BR, Pearce AN. Natural product growth inhibitors of Mycobacterium tuberculosis. Natural Product Reports. 24: 278-97. PMID 17389998 DOI: 10.1039/b513520f  1
2007 Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Webb VL, Harper JL, Copp BR. E/Z-rubrolide O, an anti-inflammatory halogenated furanone from the New Zealand ascidian Synoicum n. sp. Journal of Natural Products. 70: 111-3. PMID 17253860 DOI: 10.1021/np060188l  0.72
2006 Dodd A, Greenwood DR, Miller AL, Webb SE, Chambers SP, Copp BR, Love DR. Zebrafish: at the nexus of functional and chemical genomics. Biotechnology & Genetic Engineering Reviews. 22: 77-99. PMID 18476327  0.72
2006 Grkovic T, Kaur B, Webb VL, Copp BR. Semi-synthetic preparation of the rare, cytotoxic, deep-sea sourced sponge metabolites discorhabdins P and U. Bioorganic & Medicinal Chemistry Letters. 16: 1944-6. PMID 16439119 DOI: 10.1002/CHIN.200628193  0.56
2005 Copp BR, Christiansen HC, Lindsay BS, G Franzblau S. Identification of heteroarylenamines as a new class of antituberculosis lead molecules. Bioorganic & Medicinal Chemistry Letters. 15: 4097-9. PMID 16005211 DOI: 10.1016/J.Bmcl.2005.06.010  0.72
2005 Giddens AC, Boshoff HIM, Franzblau SG, Barry CE, Copp BR. Antimycobacterial natural products: Synthesis and preliminary biological evaluation of the oxazole-containing alkaloid texaline Tetrahedron Letters. 46: 7355-7357. DOI: 10.1016/J.Tetlet.2005.08.119  0.72
2004 Love DR, Pichler FB, Dodd A, Copp BR, Greenwood DR. Technology for high-throughput screens: the present and future using zebrafish. Current Opinion in Biotechnology. 15: 564-71. PMID 15560983 DOI: 10.1016/j.copbio.2004.09.004  0.72
2004 Marshall KM, Holden JA, Koller A, Kashman Y, Copp BR, Barrows LR. AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex. Anti-Cancer Drugs. 15: 907-13. PMID 15457132 DOI: 10.1097/00001813-200410000-00012  0.72
2004 Appleton DR, Page MJ, Lambert G, Copp BR. 1,3-dimethyl-8-oxoisoguanine, a new purine from the New Zealand ascidian Pseudodistoma cereum. Natural Product Research. 18: 39-42. PMID 14974616 DOI: 10.1080/1057563031000122077  0.56
2003 Pichler FB, Laurenson S, Williams LC, Dodd A, Copp BR, Love DR. Chemical discovery and global gene expression analysis in zebrafish. Nature Biotechnology. 21: 879-83. PMID 12894204 DOI: 10.1038/nbt852  0.72
2003 Matsumoto SS, Biggs J, Copp BR, Holden JA, Barrows LR. Mechanism of ascididemin-induced cytotoxicity. Chemical Research in Toxicology. 16: 113-22. PMID 12588181 DOI: 10.1021/Tx025618W  0.72
2002 Appleton DR, Page MJ, Lambert G, Berridge MV, Copp BR. Kottamides A-D: novel bioactive imidazolone-containing alkaloids from the New Zealand ascidian Pycnoclavella kottae. The Journal of Organic Chemistry. 67: 5402-4. PMID 12126438  0.56
2002 Appleton DR, Sewell MA, Berridge MV, Copp BR. A new biologically active malyngamide from a New Zealand collection of the sea hare Bursatella leachii. Journal of Natural Products. 65: 630-1. PMID 11975522  0.32
2001 Pearce AN, Babcock RC, Lambert G, Copp BR. N2,N2,7-trimethylguanine, a new trimethylated guanine natural product from the New Zealand ascidian, Lissoclinum notti. Natural Product Letters. 15: 237-41. PMID 11833618 DOI: 10.1080/10575630108041287  1
2001 Pearce AN, Babcock RC, Battershill CN, Lambert G, Copp BR. Enantiomeric 1,2,3-trithiane-containing alkaloids and two new 1,3-dithiane alkaloids from New Zealand ascidians. The Journal of Organic Chemistry. 66: 8257-9. PMID 11722237  1
2000 Copp BR, Lindsay BS, Oliver AG, Rickard CE. 11-methylpyrido[2,3-b]acridine-5,12-dione. Acta Crystallographica. Section C, Crystal Structure Communications. 56: 102-3. PMID 10710687 DOI: 10.1107/S0108270199013578  0.72
2000 Matsumoto SS, Sidford MH, Holden JA, Barrows LR, Copp BR. Mechanism of action studies of cytotoxic marine alkaloids: Ascididemin exhibits thiol-dependent oxidative DNA cleavage Tetrahedron Letters. 41: 1667-1670. DOI: 10.1016/S0040-4039(00)00011-3  0.72
1999 Baker LJ, Clark GR, Copp BR, Hansen RP, Squire CJ. 2-ethylthio-9-methyl-1,4-dihydroacridine-1,4-dione and 9-methyl-2-(4-tolylthio)-1,4-dihydroacridine-1,4-dione. Acta Crystallographica. Section C, Crystal Structure Communications. 55: 634-6. PMID 10227129 DOI: 10.1107/S0108270198014929  0.72
1999 Lindsay BS, Battershill CN, Copp BR. 1,3-Dimethylguanine, a new purine from the new zealand ascidian botrylloides leachi Journal of Natural Products. 62: 638-9. PMID 10217731 DOI: 10.1021/np980477c  0.72
1998 Copp BR, Fairchild CR, Cornell L, Casazza AM, Robinson S, Ireland CM. Naamidine A is an antagonist of the epidermal growth factor receptor and an in vivo active antitumor agent Journal of Medicinal Chemistry. 41: 3909-3911. PMID 9748366 DOI: 10.1021/Jm980294N  0.72
1998 Lindsay BS, Battershill CN, Copp BR. Isolation of 2-(3'-bromo-4'-hydroxyphenol)ethanamine from the New Zealand ascidian Cnemidocarpa bicornuta. Journal of Natural Products. 61: 857-8. PMID 9644087 DOI: 10.1021/np980052q  0.72
1998 De Guzman FS, Copp BR, Mayne CL, Conception GP, Mangalindan GC, Barrows LR, Ireland CM. Bolinaquinone: A novel cytotoxic sesquiterpene hydroxyquinone from a Philippine Dysidea sponge Journal of Organic Chemistry. 63: 8042-8044. DOI: 10.1021/Jo981037T  0.72
1998 Copp BR, Jompa J, Tahir A, Ireland CM. Styelsamines A-D: New tetracyclic pyridoacridine alkaloids from the indonesian ascidian eusynstyela latericius Journal of Organic Chemistry. 63: 8024-8026. DOI: 10.1021/Jo980905J  0.72
1998 Lindsay BS, Oliver AG, Rickard CEF, Copp BR. Crystal structure of the cytotoxic marine alkaloid 2-bromoleptoclinidinone Journal of Chemical Crystallography. 28: 645-648.  0.72
1995 Lindsay BS, Barrows LR, Copp BR. Structural requirements for biological activity of the marine alkaloid ascididemin Bioorganic and Medicinal Chemistry Letters. 5: 739-742. DOI: 10.1016/0960-894X(95)00106-4  0.72
1993 Barrows LR, Radisky DC, Copp BR, Swaffar DS, Kramer RA, Warters RL, Ireland CM. Makaluvamines, marine natural products, are active anti-cancer agents and DNA topo II inhibitors Anti-Cancer Drug Design. 8: 333-347. PMID 8251041  0.72
1993 Radisky DC, Radisky ES, Barrows LR, Copp BR, Kramer RA, Ireland CM. Novel cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya Journal of the American Chemical Society. 115: 1632-1638. DOI: 10.1021/Ja00058A003  0.72
1992 Copp BR, Ireland CM, Barrows LR. Psammaplysin C: A new cytotoxic dibromotyrosine-derived metabolite from the marine sponge Druinella (=Psammaplysilla) purpurea Journal of Natural Products. 55: 822-823. PMID 1522422 DOI: 10.1021/Np50084A021  0.72
1991 Copp BR, Ireland CM, Barrows LR. Wakayin: A novel cytotoxic pyrroloiminoquinone alkaloid from the ascidian Clavelina species Journal of Organic Chemistry. 56: 4596-4597. DOI: 10.1021/Jo00015A005  0.72
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