Mark Brönstrup - Publications

Affiliations: 
Chemical Biology Helmholz Centre for Infection Research 

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Felgner S, Preusse M, Beutling U, Stahnke S, Pawar V, Rohde M, Brönstrup M, Stradal T, Häussler S. Host-induced spermidine production in motile triggers phagocytic uptake. Elife. 9. PMID 32960172 DOI: 10.7554/Elife.55744  0.4
2020 Mamareli P, Kruse F, Lu CW, Guderian M, Floess S, Rox K, Allan DSJ, Carlyle JR, Brönstrup M, Müller R, Berod L, Sparwasser T, Lochner M. Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection. Mucosal Immunology. PMID 32355319 DOI: 10.1038/S41385-020-0285-7  0.44
2020 Blockus S, Sake SM, Wetzke M, Grethe C, Graalmann T, Pils M, Le Goffic R, Galloux M, Prochnow H, Rox K, Hüttel S, Rupcic Z, Wiegmann B, Dijkman R, Rameix-Welti MA, et al. Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry. Antiviral Research. 177: 104774. PMID 32197980 DOI: 10.1016/J.Antiviral.2020.104774  0.44
2020 Elgaher WAM, Hamed MM, Baumann S, Herrmann J, Siebenbürger L, Krull J, Cirnski K, Kirschning A, Brönstrup M, Müller R, Hartmann RW. Cystobactamid 507: Concise Synthesis, Mode of Action and Optimization toward More Potent Antibiotics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31984562 DOI: 10.1002/Chem.202000117  0.6
2020 Testolin G, Cirnski K, Rox K, Prochnow H, Fetz V, Grandclaudon C, Mollner T, Baiyoumy A, Ritter A, Leitner C, Krull J, Heuvel Jvd, Vassort A, Sordello S, Hamed MM, et al. Synthetic studies of cystobactamids as antibiotics and bacterial imaging carriers lead to compounds with high in vivo efficacy Chemical Science. 11: 1316-1334. DOI: 10.1039/C9Sc04769G  0.6
2020 Samarakoon MC, Thongbai B, Hyde KD, Brönstrup M, Beutling U, Lambert C, Miller AN, Liu JK(, Promputtha I, Stadler M. Elucidation of the life cycle of the endophytic genus Muscodor and its transfer to Induratia in Induratiaceae fam. nov., based on a polyphasic taxonomic approach Fungal Diversity. 101: 177-210. DOI: 10.1007/S13225-020-00443-9  0.44
2020 Elgaher WAM, Hamed MM, Baumann S, Herrmann J, Siebenbürger L, Krull J, Cirnski K, Kirschning A, Brönstrup M, Müller R, Hartmann RW. Cover Feature: Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent Antibiotics (Chem. Eur. J. 32/2020) Chemistry: a European Journal. 26: 7141-7141. DOI: 10.1002/Chem.202002127  0.6
2019 Grandclaudon C, Birudukota NVS, Elgaher WAM, Jumde RP, Yahiaoui S, Arisetti N, Hennessen F, Hüttel S, Stadler M, Herrmann J, Miethke M, Hartmann RW, Müller R, Hirsch AKH, Brönstrup M. Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics. European Journal of Medicinal Chemistry. 188: 112005. PMID 31911294 DOI: 10.1016/J.Ejmech.2019.112005  0.6
2019 Prochnow H, Rox K, Birudukota NVS, Weichert L, Hotop SK, Klahn P, Mohr K, Franz S, Banda DH, Blockus S, Schreiber J, Haid S, Oeyen M, Martinez JP, Süssmuth RD, et al. Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated virolysis. Journal of Virology. PMID 31666384 DOI: 10.1128/Jvi.01471-19  1
2019 Sommer R, Rox K, Wagner S, Hauck D, Henrikus S, Newsad S, Arnold T, Ryckmans T, Brönstrup M, Imberty A, Varrot A, Hartmann RW, Titz A. Anti-Biofilm Agents against Pseudomonas aeruginosa: a Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors. Journal of Medicinal Chemistry. PMID 31553873 DOI: 10.1021/Acs.Jmedchem.9B01120  0.36
2019 Hotop SK, Abd El Wahed A, Beutling U, Czerny F, Sievers C, Diederichsen U, Frank R, Stahl-Hennig C, Brönstrup M, Fritz HJ. Serological Analysis of Herpes B Virus at Individual Epitope Resolution: From Two dimensional Peptide Arrays to Multiplex Bead Flow Assays. Analytical Chemistry. PMID 31365232 DOI: 10.1021/Acs.Analchem.9B01291  0.4
2019 Klahn P, Fetz V, Ritter A, Collisi W, Hinkelmann B, Arnold T, Tegge W, Rox K, Hüttel S, Mohr KI, Wink J, Stadler M, Wissing J, Jänsch L, Brönstrup M. The nuclear export inhibitor aminoratjadone is a potent effector in extracellular-targeted drug conjugates. Chemical Science. 10: 5197-5210. PMID 31191875 DOI: 10.1039/C8Sc05542D  1
2019 Depke T, Franke R, Brönstrup M. CluMSID: an R package for similarity-based clustering of tandem mass spectra to aid feature annotation in metabolomics. Bioinformatics (Oxford, England). PMID 30649189 DOI: 10.1093/Bioinformatics/Btz005  0.44
2018 Fu C, Xie F, Hoffmann J, Wang Q, Bauer A, Brönstrup M, Mahmud T, Müller R. Armeniaspirol antibiotic biosynthesis: Chlorination and oxidative dechlorination steps affording spiro[4.4]non-8-ene formation. Chembiochem : a European Journal of Chemical Biology. PMID 30556942 DOI: 10.1002/Cbic.201800791  0.44
2018 Sikandar A, Cirnski K, Testolin G, Volz C, Brönstrup M, Kalinina OV, Müller R, Koehnke J. Adaptation of a Bacterial Multidrug Resistance System Revealed by the Structure and Function of AlbA. Journal of the American Chemical Society. PMID 30422653 DOI: 10.2210/Pdb6H96/Pdb  0.44
2018 Muthukumar Y, Münkemer J, Mathieu D, Richter C, Schwalbe H, Steinmetz H, Kessler W, Reichelt J, Beutling U, Frank R, Büssow K, van den Heuvel J, Brönstrup M, Taylor RE, Laschat S, et al. Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria. Plos One. 13: e0201605. PMID 30063768 DOI: 10.1371/Journal.Pone.0201605  0.4
2018 Graef F, Richter R, Fetz V, Murgia X, De Rossi C, Schneider-Daum N, Allegretta G, Elgaher WAM, Haupenthal J, Empting M, Beckmann F, Brönstrup M, Hartmann RW, Gordon S, Lehr CM. An In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics. Acs Infectious Diseases. PMID 29750862 DOI: 10.1021/Acsinfecdis.7B00165  0.6
2018 Witzgall F, Depke T, Hoffmann M, Empting M, Brönstrup M, Müller R, Blankenfeldt W. The Alkylquinolone Repertoire of Pseudomonas aeruginosa is linked to Structural Flexibility of the FabH-like PQS Biosynthesis Enzyme PqsBC. Chembiochem : a European Journal of Chemical Biology. PMID 29722462 DOI: 10.1002/Cbic.201800153  0.44
2017 Lukat P, Katsuyama Y, Wenzel S, Binz T, König C, Blankenfeldt W, Brönstrup M, Müller R. Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity. Chemical Science. 8: 7521-7527. PMID 29163906 DOI: 10.1039/C7Sc02622F  0.44
2017 Abouzeid S, Beutling U, Surup F, Abdel Bar FM, Amer MM, Badria FA, Yahyazadeh M, Brönstrup M, Selmar D. Treatment of Vinca minor Leaves with Methyl Jasmonate Extensively Alters the Pattern and Composition of Indole Alkaloids. Journal of Natural Products. PMID 29131648 DOI: 10.1021/Acs.Jnatprod.7B00424  0.4
2017 Müller R, Hüttel S, Testolin G, Herrmann J, Planke T, Gille F, Moreno M, Stadler M, Brönstrup M, Kirschning A. Discovery and total synthesis of natural cystobactamid derivatives with superior activity against Gram-negative pathogens. Angewandte Chemie (International Ed. in English). PMID 28730677 DOI: 10.1002/Anie.201705913  0.6
2017 Depke T, Franke R, Brönstrup M. Clustering of MS(2) spectra using unsupervised methods to aid the identification of secondary metabolites from Pseudomonas aeruginosa. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. PMID 28642031 DOI: 10.1016/J.Jchromb.2017.06.002  0.44
2017 Klahn P, Brönstrup M. Bifunctional antimicrobial conjugates and hybrid antimicrobials. Natural Product Reports. 34: 832-885. PMID 28530279 DOI: 10.1039/C7Np00006E  1
2016 Klahn P, Brönstrup M. New Structural Templates for Clinically Validated and Novel Targets in Antimicrobial Drug Research and Development. Current Topics in Microbiology and Immunology. PMID 27704270 DOI: 10.1007/82_2016_501  1
2016 Schreuder H, Liesum A, Lönze P, Stump H, Hoffmann H, Schiell M, Kurz M, Toti L, Bauer A, Kallus C, Klemke-Jahn C, Czech J, Kramer D, Enke H, Niedermeyer TH, et al. Isolation, Co-Crystallization and Structure-Based Characterization of Anabaenopeptins as Highly Potent Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa). Scientific Reports. 6: 32958. PMID 27604544 DOI: 10.1038/Srep32958  0.72
2016 Nicolaou KC, Pulukuri KK, Rigol S, Heretsch P, Yu R, Grove CI, Hale CR, ElMarrouni A, Fetz V, Brönstrup M, Aujay M, Sandoval J, Gavrilyuk J. Synthesis and Biological Investigation of Δ(12)-Prostaglandin J3 (Δ(12)-PGJ3) Analogues and Related Compounds. Journal of the American Chemical Society. PMID 27171618 DOI: 10.1021/Jacs.6B02075  0.32
2015 Wenzel SC, Hoffmann H, Zhang J, Debussche L, Haag-Richter S, Kurz M, Nardi F, Lukat P, Kochems I, Tietgen H, Schummer D, Nicolas JP, Calvet L, Czepczor V, Vrignaud P, et al. Production of the Bengamide Class of Marine Natural Products in Myxobacteria: Biosynthesis and Structure-Activity Relationships. Angewandte Chemie (International Ed. in English). PMID 26514647 DOI: 10.1002/Anie.201508277  0.72
2015 Koutsoudakis G, Romero-Brey I, Berger C, Pérez-Vilaró G, Perin PM, Vondran FW, Kalesse M, Harmrolfs K, Müller R, Martinez JP, Pietschmann T, Bartenschlager R, Brönstrup M, Meyerhans A, Díez J. Soraphen A: a broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity. Journal of Hepatology. PMID 26070407 DOI: 10.1016/J.Jhep.2015.06.002  0.32
2015 Kling A, Lukat P, Almeida DV, Bauer A, Fontaine E, Sordello S, Zaburannyi N, Herrmann J, Wenzel SC, König C, Ammerman NC, Barrio MB, Borchers K, Bordon-Pallier F, Brönstrup M, et al. Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins. Science (New York, N.Y.). 348: 1106-12. PMID 26045430 DOI: 10.1126/Science.Aaa4690  0.72
2015 Fu C, Keller L, Bauer A, Brönstrup M, Froidbise A, Hammann P, Herrmann J, Mondesert G, Kurz M, Schiell M, Schummer D, Toti L, Wink J, Müller R. Biosynthetic Studies of Telomycin Reveal New Lipopeptides with Enhanced Activity. Journal of the American Chemical Society. 137: 7692-705. PMID 26043159 DOI: 10.1021/Jacs.5B01794  0.32
2015 Hoffmann H, Kogler H, Heyse W, Matter H, Caspers M, Schummer D, Klemke-Jahn C, Bauer A, Penarier G, Debussche L, Brönstrup M. Discovery, Structure Elucidation, and Biological Characterization of Nannocystin A, a Macrocyclic Myxobacterial Metabolite with Potent Antiproliferative Properties. Angewandte Chemie (International Ed. in English). PMID 26031409 DOI: 10.1002/Anie.201411377  0.72
2015 Halland N, Brönstrup M, Czech J, Czechtizky W, Evers A, Follmann M, Kohlmann M, Schiell M, Kurz M, Schreuder HA, Kallus C. Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa) from Natural Product Anabaenopeptin. Journal of Medicinal Chemistry. 58: 4839-44. PMID 25990761 DOI: 10.1021/Jm501840B  0.72
2015 Martinez JP, Sasse F, Brönstrup M, Diez J, Meyerhans A. Antiviral drug discovery: broad-spectrum drugs from nature. Natural Product Reports. 32: 29-48. PMID 25315648 DOI: 10.1039/C4Np00085D  0.72
2013 Férir G, Petrova MI, Andrei G, Huskens D, Hoorelbeke B, Snoeck R, Vanderleyden J, Balzarini J, Bartoschek S, Brönstrup M, Süssmuth RD, Schols D. The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications. Plos One. 8: e64010. PMID 23724015 DOI: 10.1371/Journal.Pone.0064010  0.72
2012 Dufour C, Wink J, Kurz M, Kogler H, Olivan H, Sablé S, Heyse W, Gerlitz M, Toti L, Nußer A, Rey A, Couturier C, Bauer A, Brönstrup M. Isolation and structural elucidation of armeniaspirols A-C: potent antibiotics against gram-positive pathogens. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 16123-8. PMID 23143837 DOI: 10.1002/Chem.201201635  0.72
2010 Meindl K, Schmiederer T, Schneider K, Reicke A, Butz D, Keller S, Gühring H, Vértesy L, Wink J, Hoffmann H, Brönstrup M, Sheldrick GM, Süssmuth RD. Labyrinthopeptins: a new class of carbacyclic lantibiotics. Angewandte Chemie (International Ed. in English). 49: 1151-4. PMID 20082397 DOI: 10.1002/Anie.200905773  0.72
2003 Segeth MP, Bonnefoy A, Brönstrup M, Knauf M, Schummer D, Toti L, Vértesy L, Wetzel-Raynal MC, Wink J, Seibert G. Coniosetin, a novel tetramic acid antibiotic from Coniochaeta ellipsoidea DSM 13856. The Journal of Antibiotics. 56: 114-22. PMID 12715870 DOI: 10.7164/Antibiotics.56.114  0.32
2003 Hoffmann RW, Brönstrup M, Müller M. The second step of the halogen/metal exchange reaction. Organic Letters. 5: 313-6. PMID 12556180 DOI: 10.1021/Ol027307I  0.72
2003 Müller M, Brönstrup M, Knopff O, Schulze V, Hoffmann RW. Energetics of iodine ate complexes, intermediates in the iodine/magnesium exchange on 1,1-diiodoalkanes Organometallics. 22: 2931-2937. DOI: 10.1021/Om0210210  0.72
2003 Böhm VPW, Schulze V, Brönstrup M, Müller M, Hoffmann RW. Evidence for an iodine ate complex as an observable intermediate in the iodine/magnesium exchange on a 1,1-diiodoalkane Organometallics. 22: 2925-2930. DOI: 10.1021/Om0210208  0.72
2003 Schröder D, Engeser M, Brönstrup M, Daniel C, Spandl J, Hartl H. Ion chemistry of the hexanuclear methoxo-oxovanadium cluster V6O7(OCH3)12 International Journal of Mass Spectrometry. 228: 743-757. DOI: 10.1016/S1387-3806(03)00236-7  0.72
2002 Vértesy L, Beck B, Brönstrup M, Ehrlich K, Kurz M, Müller G, Schummer D, Seibert G. Cyclipostins, novel hormone-sensitive lipase inhibitors from Streptomyces sp. DSM 13381. II. Isolation, structure elucidation and biological properties. The Journal of Antibiotics. 55: 480-94. PMID 12139017 DOI: 10.7164/Antibiotics.55.480  0.36
2002 Hopmann C, Kurz M, Brönstrup M, Wink J, LeBeller D. Isolation and structure elucidation of vancoresmycin-a new antibiotic from Amycolatopsis sp. ST 101170 Tetrahedron Letters. 43: 435-438. DOI: 10.1016/S0040-4039(01)02171-2  0.32
2001 Brönstrup M, Schröder D, Kretzschmar I, Schwarz H, Harvey JN. Platinum dioxide cation: easy to generate experimentally but difficult to describe theoretically. Journal of the American Chemical Society. 123: 142-7. PMID 11273611 DOI: 10.1021/Ja003138Q  0.72
2000 Brönstrup M, Schröder D, Schwarz H. A mechanistic study of the FeO+-mediated decomposition pathways of phenol, anisol, and their thio analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 91-104. PMID 10747392 DOI: 10.1002/(Sici)1521-3765(20000103)6:1<91::Aid-Chem91>3.0.Co;2-7  0.72
1999 Müller M, Stiasny HC, Brönstrup M, Burton A, Hoffmann RW. Chiral organometallic reagents. Part XXIV.1 Iodine ate-complexes as intermediates in the iodine-lithium exchange reaction on 1,1-diiodoalkanes Journal of the Chemical Society. Perkin Transactions 2. 731-736. DOI: 10.1039/A900121B  0.72
1999 Diefenbach M, Brönstrup M, Aschi M, Schröder aD, Schwarz H. HCN Synthesis from Methane and Ammonia: Mechanisms of Pt+-Mediated C−N Coupling Journal of the American Chemical Society. 121: 10614-10625. DOI: 10.1021/Ja992642W  0.72
1998 Aschi M, Brönstrup M, Diefenbach M, Harvey JN, Schröder D, Schwarz H. A Gas-Phase Model for the Pt -Catalyzed Coupling of Methane and Ammonia. Angewandte Chemie (International Ed. in English). 37: 829-832. PMID 29711389 DOI: 10.1002/(Sici)1521-3773(19980403)37:6<829::Aid-Anie829>3.0.Co;2-N  0.72
1998 Aschi M, Brönstrup M, Diefenbach M, Harvey JN, Schröder D, Schwarz H. Ein Gasphasenmodell für die Pt+‐katalysierte Kupplung von Methan und Ammoniak Angewandte Chemie. 110: 858-861. DOI: 10.1002/(Sici)1521-3757(19980316)110:6<858::Aid-Ange858>3.0.Co;2-H  0.72
1998 Brönstrup M, Schröder D, Kretzschmar I, Schalley CA, Schwarz H. Mass-spectrometric experiments together with electronic structure calculations support the existence of the elusive ammonia oxide molecule and its radical cation European Journal of Inorganic Chemistry. 1529-1538. DOI: 10.1002/(Sici)1099-0682(199810)1998:10<1529::Aid-Ejic1529>3.0.Co;2-Y  0.72
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