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Scott Horowitz - Publications

Affiliations: 
2013 Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
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34/52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Son A, Smetana JS, Horowitz S, Lennon CW. An intein-based biosensor to measure protein stability in vivo. Protein Science : a Publication of the Protein Society. 33: e4925. PMID 38380775 DOI: 10.1002/pro.4925  0.333
2023 Litberg TJ, Sannapureddi RKR, Huang Z, Son A, Sathyamoorthy B, Horowitz S. Why are G-quadruplexes good at preventing protein aggregation? Rna Biology. 20: 495-509. PMID 37493593 DOI: 10.1080/15476286.2023.2228572  0.751
2023 Son A, Huizar Cabral V, Huang Z, Litberg TJ, Horowitz S. G-quadruplexes rescuing protein folding. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216308120. PMID 37155907 DOI: 10.1073/pnas.2216308120  0.788
2022 Guzman BB, Son A, Litberg TJ, Huang Z, Dominguez D, Horowitz S. Emerging Roles for G-Quadruplexes in Proteostasis. The Febs Journal. PMID 36017725 DOI: 10.1111/febs.16608  0.783
2020 Begeman A, Son A, Litberg TJ, Wroblewski TH, Gehring T, Huizar Cabral V, Bourne J, Xuan Z, Horowitz S. G-Quadruplexes act as sequence-dependent protein chaperones. Embo Reports. e49735. PMID 32945124 DOI: 10.15252/Embr.201949735  0.778
2020 Son A, Horowitz S, Seong BL. Chaperna: linking the ancient RNA and protein worlds. Rna Biology. 1-8. PMID 32781880 DOI: 10.1080/15476286.2020.1801199  0.366
2019 Litberg TJ, Docter B, Hughes MP, Bourne J, Horowitz S. DNA Facilitates Oligomerization and Prevents Aggregation via DNA Networks. Biophysical Journal. PMID 31839258 DOI: 10.1016/J.Bpj.2019.11.022  0.762
2019 Rocchio S, Duman R, El Omari K, Mykhaylyk V, Orr C, Yan Z, Salmon L, Wagner A, Bardwell JCA, Horowitz S. Identifying dynamic, partially occupied residues using anomalous scattering. Acta Crystallographica. Section D, Structural Biology. 75: 1084-1095. PMID 31793902 DOI: 10.1107/S2059798319014475  0.664
2019 Fick RJ, Horowitz S, McDole BG, Clay MC, Mehl RA, Al-Hashimi HM, Scheiner S, Trievel RC. Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1. Biochemistry. PMID 30810306 DOI: 10.1021/Acs.Biochem.8B01141  0.586
2018 Horowitz S, Salmon L, Koldewey P, Ahlstrom LS, Martin R, Quan S, Afonine PV, van den Bedem H, Wang L, Xu Q, Trievel RC, Brooks CL, Bardwell JCA. Reply to 'Misreading chaperone-substrate complexes from random noise'. Nature Structural & Molecular Biology. PMID 30297780 DOI: 10.1038/S41594-018-0145-2  0.624
2018 Salmon L, Ahlstrom LS, Bardwell JCA, Horowitz S. Selecting Conformational Ensembles Using Residual Electron and Anomalous Density (READ). Methods in Molecular Biology (Clifton, N.J.). 1764: 491-504. PMID 29605935 DOI: 10.1007/978-1-4939-7759-8_31  0.687
2017 Salmon L, Stull F, Sayle S, Cato C, Akgül Ş, Foit L, Ahlstrom LS, Eisenmesser EZ, Al-Hashimi HM, Bardwell JCA, Horowitz S. The Mechanism of HdeA Unfolding and Chaperone Activation. Journal of Molecular Biology. PMID 29138002 DOI: 10.1016/J.Jmb.2017.11.002  0.755
2017 Horowitz S, Koldewey P, Stull F, Bardwell JC. Folding while bound to chaperones. Current Opinion in Structural Biology. 48: 1-5. PMID 28734135 DOI: 10.1016/J.Sbi.2017.06.009  0.481
2017 Koldewey P, Horowitz S, Bardwell JCA. Chaperone-client interactions: non-specificity engenders multi-functionality. The Journal of Biological Chemistry. PMID 28620048 DOI: 10.1074/Jbc.R117.796862  0.432
2016 Johansson KE, Johansen NT, Christensen S, Horowitz S, Bardwell JC, Olsen JG, Willemoës M, Lindorff-Larsen K, Ferkinghoff-Borg J, Hamelryck T, Winther JR. Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template. Journal of Molecular Biology. PMID 27659562 DOI: 10.1016/J.Jmb.2016.09.013  0.394
2016 Horowitz S, Koepnick B, Martin R, Tymieniecki A, Winburn AA, Cooper S, Flatten J, Rogawski DS, Koropatkin NM, Hailu TT, Jain N, Koldewey P, Ahlstrom LS, Chapman MR, Sikkema AP, et al. Determining crystal structures through crowdsourcing and coursework. Nature Communications. 7: 12549. PMID 27633552 DOI: 10.1038/Ncomms12549  0.321
2016 Salmon L, Ahlstrom LS, Horowitz S, Dickson A, Brooks CL, Bardwell JC. Capturing a dynamic chaperone-substrate interaction using NMR-informed molecular modeling. Journal of the American Chemical Society. PMID 27415450 DOI: 10.1021/Jacs.6B02382  0.7
2016 Koldewey P, Stull F, Horowitz S, Martin R, Bardwell JC. Forces Driving Chaperone Action. Cell. PMID 27293188 DOI: 10.1016/J.Cell.2016.05.054  0.43
2016 Horowitz S, Salmon L, Koldewey P, Ahlstrom LS, Martin R, Quan S, Afonine PV, van den Bedem H, Wang L, Xu Q, Trievel RC, Brooks CL, Bardwell JC. Visualizing chaperone-assisted protein folding. Nature Structural & Molecular Biology. PMID 27239796 DOI: 10.1038/Nsmb.3237  0.737
2016 Docter BE, Horowitz S, Gray MJ, Jakob U, Bardwell JC. Do nucleic acids moonlight as molecular chaperones? Nucleic Acids Research. PMID 27105849 DOI: 10.1093/Nar/Gkw291  0.481
2016 Groitl B, Horowitz S, Makepeace KA, Petrotchenko EV, Borchers CH, Reichmann D, Bardwell JC, Jakob U. Protein unfolding as a switch from self-recognition to high-affinity client binding. Nature Communications. 7: 10357. PMID 26787517 DOI: 10.1038/Ncomms10357  0.394
2016 Ahlstrom LS, Salmon L, Horowitz S, Dickson A, Brooks CL, Bardwell JC. NMR-Informed Molecular Modeling Uncovers the Conformational Landscape of Chaperone Binding with Unfolded Substrate Biophysical Journal. 110: 369a. DOI: 10.1016/J.Bpj.2015.11.1989  0.708
2015 Fick RJ, Kroner GM, Nepal B, Magnani R, Horowitz S, Houtz RL, Scheiner S, Trievel RC. Sulfur - Oxygen Chalcogen Bonding Mediates AdoMet Recognition in the Lysine Methyltransferase SET7/9. Acs Chemical Biology. PMID 26713889 DOI: 10.1021/Acschembio.5B00852  0.336
2015 Dahl JU, Koldewey P, Salmon L, Horowitz S, Bardwell JC, Jakob U. HdeB functions as an acid-protective chaperone in bacteria. The Journal of Biological Chemistry. 290: 9950. PMID 25888567 DOI: 10.1074/Jbc.A114.612986  0.655
2015 Yesselman JD, Horowitz S, Brooks CL, Trievel RC. Frequent side chain methyl carbon-oxygen hydrogen bonding in proteins revealed by computational and stereochemical analysis of neutron structures. Proteins. 83: 403-10. PMID 25401519 DOI: 10.1002/Prot.24724  0.731
2015 Dahl JU, Koldewey P, Salmon L, Horowitz S, Bardwell JC, Jakob U. HdeB functions as an acid-protective chaperone in bacteria. The Journal of Biological Chemistry. 290: 65-75. PMID 25391835 DOI: 10.1074/Jbc.M114.612986  0.699
2015 Yesselman JD, Horowitz S, Brooks CL, Trievel RC. Frequent side chain methyl carbon-oxygen hydrogen bonding in proteins revealed by computational and stereochemical analysis of neutron structures Proteins: Structure, Function and Bioinformatics. 83: 403-410. DOI: 10.1002/prot.24724  0.71
2014 Horowitz S, Adhikari U, Dirk LM, Del Rizzo PA, Mehl RA, Houtz RL, Al-Hashimi HM, Scheiner S, Trievel RC. Manipulating unconventional CH-based hydrogen bonding in a methyltransferase via noncanonical amino acid mutagenesis. Acs Chemical Biology. 9: 1692-7. PMID 24914947 DOI: 10.1021/Cb5001185  0.587
2014 Quan S, Wang L, Petrotchenko EV, Makepeace KA, Horowitz S, Yang J, Zhang Y, Borchers CH, Bardwell JC. Super Spy variants implicate flexibility in chaperone action. Elife. 3: e01584. PMID 24497545 DOI: 10.7554/Elife.01584  0.404
2013 Horowitz S, Dirk LM, Yesselman JD, Nimtz JS, Adhikari U, Mehl RA, Scheiner S, Houtz RL, Al-Hashimi HM, Trievel RC. Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases. Journal of the American Chemical Society. 135: 15536-48. PMID 24093804 DOI: 10.1021/Ja407140K  0.753
2013 Frank AT, Horowitz S, Andricioaei I, Al-Hashimi HM. Utility of 1H NMR chemical shifts in determining RNA structure and dynamics. The Journal of Physical Chemistry. B. 117: 2045-52. PMID 23320790 DOI: 10.1021/Jp310863C  0.561
2012 Horowitz S, Trievel RC. Carbon-oxygen hydrogen bonding in biological structure and function. The Journal of Biological Chemistry. 287: 41576-82. PMID 23048026 DOI: 10.1074/Jbc.R112.418574  0.387
2011 Horowitz S, Yesselman JD, Al-Hashimi HM, Trievel RC. Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9. The Journal of Biological Chemistry. 286: 18658-63. PMID 21454678 DOI: 10.1074/Jbc.M111.232876  0.751
2011 Horowitz S, Al-Hashimi H, Trievel R. Evidence for Carbon-Oxygen Hydrogen Bonding in Lysine Methyltransferase Set7/9 by NMR Chemical Shift Biophysical Journal. 100: 66a. DOI: 10.1016/J.Bpj.2010.12.560  0.591
Low-probability matches (unlikely to be authored by this person)
2016 Vander Meulen KA, Horowitz S, Trievel RC, Butcher SE. Measuring the Kinetics of Molecular Association by Isothermal Titration Calorimetry. Methods in Enzymology. 567: 181-213. PMID 26794355 DOI: 10.1016/Bs.Mie.2015.08.012  0.298
2011 Krishnan S, Horowitz S, Trievel RC. Structure and function of histone H3 lysine 9 methyltransferases and demethylases. Chembiochem : a European Journal of Chemical Biology. 12: 254-63. PMID 21243713 DOI: 10.1002/Cbic.201000545  0.291
2016 Horowitz S, Bardwell JC. RNAs as chaperones. Rna Biology. 0. PMID 27791471 DOI: 10.1080/15476286.2016.1247147  0.287
2014 Horowitz S, Koldewey P, Bardwell JC. Undergraduates improve upon published crystal structure in class assignment. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 42: 398-404. PMID 25044946 DOI: 10.1002/Bmb.20811  0.285
2019 Khatib F, Desfosses A, Koepnick B, Flatten J, Popović Z, Baker D, Cooper S, Gutsche I, Horowitz S. Building de novo cryo-electron microscopy structures collaboratively with citizen scientists. Plos Biology. 17: e3000472. PMID 31714936 DOI: 10.1371/Journal.Pbio.3000472  0.256
2013 Quan S, Wang L, Petrotchenko EV, Makepeace KA, Horowitz S, Yang J, Zhang Y, Borchers CH, Bardwell JC. Author response: Super Spy variants implicate flexibility in chaperone action Elife. DOI: 10.7554/Elife.01584.024  0.231
2007 Horowitz S, Binion DG, Nelson VM, Kanaa Y, Javadi P, Lazarova Z, Andrekopoulos C, Kalyanaraman B, Otterson MF, Rafiee P. Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G1323-36. PMID 17218473 DOI: 10.1152/Ajpgi.00499.2006  0.224
2016 Horowitz S, Koepnick B, Martin R, Tymieniecki A, Winburn AA, Cooper S, Flatten J, Rogawski DS, Koropatkin NM, Hailu TT, Jain N, Koldewey P, Ahlstrom LS, Chapman MR, Sikkema AP, et al. Corrigendum: Determining crystal structures through crowdsourcing and coursework. Nature Communications. 7: 13392. PMID 27779204 DOI: 10.1038/Ncomms13392  0.224
2020 Leman JK, Weitzner BD, Lewis SM, Adolf-Bryfogle J, Alam N, Alford RF, Aprahamian M, Baker D, Barlow KA, Barth P, Basanta B, Bender BJ, Blacklock K, Bonet J, Boyken SE, ... ... Horowitz S, et al. Macromolecular modeling and design in Rosetta: recent methods and frameworks. Nature Methods. PMID 32483333 DOI: 10.1038/S41592-020-0848-2  0.217
2019 Dsilva L, Mittal S, Koepnick B, Flatten J, Cooper S, Horowitz S. Creating custom foldit puzzles for teaching biochemistry. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. PMID 30638297 DOI: 10.1002/Bmb.21208  0.205
2006 Rafiee P, Theriot ME, Nelson VM, Heidemann J, Kanaa Y, Horowitz SA, Rogaczewski A, Johnson CP, Ali I, Shaker R, Binion DG. Human esophageal microvascular endothelial cells respond to acidic pH stress by PI3K/AKT and p38 MAPK-regulated induction of Hsp70 and Hsp27. American Journal of Physiology. Cell Physiology. 291: C931-45. PMID 16790501 DOI: 10.1152/ajpcell.00474.2005  0.168
2020 Miller JA, Khatib F, Hammond H, Cooper S, Horowitz S. Introducing Foldit Education Mode. Nature Structural & Molecular Biology. PMID 32807992 DOI: 10.1038/S41594-020-0485-6  0.164
2023 Kallweit L, Hamlett ED, Saternos H, Gilmore A, Granholm AC, Horowitz S. A New Role for RNA G-quadruplexes in Aging and Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 37873355 DOI: 10.1101/2023.10.02.560545  0.157
2022 Ahmed J, Fitch TC, Donnelly CM, Joseph JA, Ball TD, Bassil MM, Son A, Zhang C, Ledreux A, Horowitz S, Qin Y, Paredes D, Kumar S. Foldamers reveal and validate therapeutic targets associated with toxic α-synuclein self-assembly. Nature Communications. 13: 2273. PMID 35477706 DOI: 10.1038/s41467-022-29724-4  0.152
2024 Litberg TJ, Horowitz S. Roles of Nucleic Acids in Protein Folding, Aggregation, and Disease. Acs Chemical Biology. PMID 38477936 DOI: 10.1021/acschembio.3c00695  0.12
2014 Tabares-Velasco PC, Maguire J, Horowitz S, Christensen C. Using the beopt automated residential simulation test suite to enable comparative analysis between energy simulation engines 2014 Ashrae/Ibpsa-Usa Building Simulation Conference. 41-48.  0.054
2020 Millstein A, Myers-Coffman K, Horowitz S, Kesslick A, Bradt J. Experiences of implementing treatment manuals: Clinician, supervisor, and researcher reflections. Nordic Journal of Music Therapy. 30: 179-191. PMID 36035073 DOI: 10.1080/08098131.2020.1790632  0.029
2011 Horowitz DL, Katzap E, Horowitz S, Barilla-LaBarca ML. Approach to septic arthritis. American Family Physician. 84: 653-60. PMID 21916390  0.01
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