Year |
Citation |
Score |
2025 |
Chen S, Goncin U, Zhu J, Su SP, Czyzyk TA, Miller CO, Kashfi Sadabad R, Bogyo M. A caspase-1-cathepsin AND-gate probe for selective imaging of inflammasome activation. Biorxiv : the Preprint Server For Biology. PMID 40501809 DOI: 10.1101/2025.05.27.656501 |
0.421 |
|
2025 |
Upadhyay T, Woods EC, Dela Ahator S, Julin K, Faucher FF, Uddin MJ, Hollander MJ, Pedowitz NJ, Abegg D, Hammond I, Eke IE, Wang S, Chen S, Bennett JM, Jo J, et al. Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation. Nature Communications. 16: 5046. PMID 40447595 DOI: 10.1038/s41467-025-60367-3 |
0.506 |
|
2024 |
Bogyo M, Upadhyay T, Woods E, Ahator S, Julin K, Faucher F, Hollander M, Pedowitz N, Abegg D, Hammond I, Eke I, Wang S, Chen S, Bennett J, Jo J, et al. Covalent-fragment screening identifies selective inhibitors of multiple Staphylococcus aureus serine hydrolases important for growth and biofilm formation. Research Square. PMID 39711551 DOI: 10.21203/rs.3.rs-5494070/v1 |
0.641 |
|
2024 |
Zhang H, Xing Y, Yang Y, Tang B, Zong Z, Li J, Zang Y, Bogyo M, Lu X, Chen S. DNA-Encoded Noncanonical Substrate Library for Protease Profiling. Chembiochem : a European Journal of Chemical Biology. e202400559. PMID 39299917 DOI: 10.1002/cbic.202400559 |
0.557 |
|
2024 |
Lan T, Peng C, Yao X, Chan RST, Wei T, Rupanya A, Radakovic A, Wang S, Chen S, Lovell S, Snyder SA, Bogyo M, Dickinson BC. Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display. Journal of the American Chemical Society. PMID 39136646 DOI: 10.1021/jacs.4c07851 |
0.71 |
|
2024 |
Xing Y, Zhang H, Wang Y, Zong Z, Bogyo M, Chen S. DNA encoded peptide library for SARS-CoV-2 3CL protease covalent inhibitor discovery and profiling. Rsc Chemical Biology. 5: 691-702. PMID 38966676 DOI: 10.1039/d4cb00097h |
0.659 |
|
2024 |
Hadzima M, Faucher FF, Blažková K, Yim JJ, Guerra M, Chen S, Woods EC, Park KW, Šácha P, Šubr V, Kostka L, Etrych T, Majer P, Konvalinka J, Bogyo M. Polymer-Tethered Quenched Fluorescent Probes for Enhanced Imaging of Tumor-Associated Proteases. Acs Sensors. PMID 38941307 DOI: 10.1021/acssensors.4c00912 |
0.465 |
|
2024 |
Hadzima M, Faucher F, Blažková K, Yim JJ, Guerra M, Chen S, Woods EC, Park KW, Šácha P, Šubr V, Kostka L, Etrych T, Majer P, Konvalinka J, Bogyo M. Polymer-tethered quenched fluorescent probes for enhanced imaging of tumor associated proteases. Biorxiv : the Preprint Server For Biology. PMID 38766164 DOI: 10.1101/2024.05.06.592849 |
0.465 |
|
2021 |
Zhang H, Chen S. Cyclic peptide drugs approved in the last two decades (2001-2021). Rsc Chemical Biology. 3: 18-31. PMID 35128405 DOI: 10.1039/d1cb00154j |
0.476 |
|
2020 |
Chen S, Lovell S, Lee S, Fellner M, Mace PD, Bogyo M. Identification of highly selective covalent inhibitors by phage display. Nature Biotechnology. PMID 33199876 DOI: 10.1038/s41587-020-0733-7 |
0.602 |
|
2019 |
Chen S, Yim JJ, Bogyo M. Synthetic and biological approaches to map substrate specificities of proteases. Biological Chemistry. PMID 31639098 DOI: 10.1515/Hsz-2019-0332 |
0.571 |
|
2015 |
Baeriswyl V, Calzavarini S, Chen S, Zorzi A, Bologna L, Angelillo-Scherrer A, Heinis C. A Synthetic Factor XIIa Inhibitor Blocks Selectively Intrinsic Coagulation Initiation. Acs Chemical Biology. 10: 1861-70. PMID 25989088 DOI: 10.1021/acschembio.5b00103 |
0.685 |
|
2015 |
Chen S, Heinis C. Phage selection of bicyclic peptides based on two disulfide bridges. Methods in Molecular Biology (Clifton, N.J.). 1248: 119-37. PMID 25616330 DOI: 10.1007/978-1-4939-2020-4_9 |
0.733 |
|
2014 |
Chen S, Gopalakrishnan R, Schaer T, Marger F, Hovius R, Bertrand D, Pojer F, Heinis C. Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides. Nature Chemistry. 6: 1009-16. PMID 25343607 DOI: 10.1038/Nchem.2043 |
0.688 |
|
2014 |
Bellotto S, Chen S, Rentero Rebollo I, Wegner HA, Heinis C. Phage selection of photoswitchable peptide ligands. Journal of the American Chemical Society. 136: 5880-3. PMID 24702159 DOI: 10.1021/ja501861m |
0.699 |
|
2014 |
Chen S, Bertoldo D, Angelini A, Pojer F, Heinis C. Peptide ligands stabilized by small molecules. Angewandte Chemie (International Ed. in English). 53: 1602-6. PMID 24453110 DOI: 10.1002/anie.201309459 |
0.723 |
|
2014 |
Chen S, Touati J, Heinis C. Tracking chemical reactions on the surface of filamentous phage using mass spectrometry. Chemical Communications (Cambridge, England). 50: 5267-9. PMID 24291807 DOI: 10.1039/c3cc47496h |
0.646 |
|
2013 |
Chen S, Gfeller D, Buth SA, Michielin O, Leiman PG, Heinis C. Improving binding affinity and stability of peptide ligands by substituting glycines with D-amino acids. Chembiochem : a European Journal of Chemical Biology. 14: 1316-22. PMID 23828687 DOI: 10.1002/Cbic.201300228 |
0.697 |
|
2013 |
Lee B, Chen S, Heinis C, Scopelliti R, Severin K. Pattern-based sensing of peptides and aminoglycosides with a single molecular probe. Organic Letters. 15: 3456-9. PMID 23796050 DOI: 10.1021/Ol401495C |
0.657 |
|
2013 |
Chen S, Rentero Rebollo I, Buth SA, Morales-Sanfrutos J, Touati J, Leiman PG, Heinis C. Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries. Journal of the American Chemical Society. 135: 6562-9. PMID 23560397 DOI: 10.1021/Ja400461H |
0.71 |
|
2012 |
Angelini A, Morales-Sanfrutos J, Diderich P, Chen S, Heinis C. Bicyclization and tethering to albumin yields long-acting peptide antagonists. Journal of Medicinal Chemistry. 55: 10187-97. PMID 23088498 DOI: 10.1021/jm301276e |
0.711 |
|
2012 |
Chen S, Morales-Sanfrutos J, Angelini A, Cutting B, Heinis C. Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides. Chembiochem : a European Journal of Chemical Biology. 13: 1032-8. PMID 22492661 DOI: 10.1002/cbic.201200049 |
0.727 |
|
2012 |
Baeriswyl V, Rapley H, Pollaro L, Stace C, Teufel D, Walker E, Chen S, Winter G, Tite J, Heinis C. Bicyclic peptides with optimized ring size inhibit human plasma kallikrein and its orthologues while sparing paralogous proteases. Chemmedchem. 7: 1173-6. PMID 22492508 DOI: 10.1002/cmdc.201200071 |
0.69 |
|
2012 |
Angelini A, Cendron L, Chen S, Touati J, Winter G, Zanotti G, Heinis C. Bicyclic peptide inhibitor reveals large contact interface with a protease target. Acs Chemical Biology. 7: 817-21. PMID 22304751 DOI: 10.1021/cb200478t |
0.752 |
|
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