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Pavel Nagorny - Publications

Affiliations: 
Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Total Synthesis, Chemical Glycobiology
Website:
https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=nagorny

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wang S, Zhelavskyi O, Lee J, Argüelles AJ, Khomutnyk YY, Mensah E, Guo H, Hourani R, Zimmerman PM, Nagorny P. Studies of Catalyst-Controlled Regioselective Acetalization and Its Application to Single-Pot Synthesis of Differentially Protected Saccharides. Journal of the American Chemical Society. PMID 34705439 DOI: 10.1021/jacs.1c08448  0.7
2021 Fejedelem Z, Carney N, Nagorny P. Synthesis of Cardiotonic Steroids Oleandrigenin and Rhodexin B. The Journal of Organic Chemistry. PMID 34255963 DOI: 10.1021/acs.joc.1c00985  0.327
2021 Kim S, Khomutnyk Y, Bannykh A, Nagorny P. Synthesis of Glycosyl Fluorides by Photochemical Fluorination with Sulfur(VI) Hexafluoride. Organic Letters. 23: 190-194. PMID 33354969 DOI: 10.1021/acs.orglett.0c03915  0.752
2020 Khatri HR, Carney N, Rutkoski R, Bhattarai B, Nagorny P. Recent Progress in Steroid Synthesis Triggered by the Emergence of New Catalytic Methods. European Journal of Organic Chemistry. 2020: 755-776. PMID 32601521  0.718
2020 Sun S, Nagorny P. Exploration of chiral diastereomeric spiroketal (SPIROL)-based phosphinite ligands in asymmetric hydrogenation of heterocycles. Chemical Communications (Cambridge, England). PMID 32579621 DOI: 10.1039/D0Cc03088K  0.309
2020 Wang S, Arguelles AJ, Tay JH, Hotta M, Zimmerman PM, Nagorny P. Experimental and Computational Studies on Regiodivergent Chiral Phosphoric Acid Catalyzed Cycloisomerization of Mupirocin Methyl Ester. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31905253 DOI: 10.1002/Chem.201905222  0.625
2020 Khatri HR, Carney N, Rutkoski R, Bhattarai B, Nagorny P. Recent Progress in Steroid Synthesis Triggered by the Emergence of New Catalytic Methods European Journal of Organic Chemistry. 2020: 755-776. DOI: 10.1002/Ejoc.201901466  0.73
2019 Tay JH, Dorokhov V, Wang S, Nagorny P. Regioselective single pot C3-glycosylation of strophanthidol using methylboronic acid as a transient protecting group. The Journal of Antibiotics. PMID 30948784 DOI: 10.1038/S41429-019-0172-1  0.372
2019 Khatri HR, Bhattarai B, Kaplan W, Li Z, Long MJC, Aye Y, Nagorny P. Modular total synthesis and cell-based anticancer activity evaluation of ouabagenin and other cardiotonic steroids with varying degrees of oxygenation. Journal of the American Chemical Society. PMID 30802047 DOI: 10.1021/Jacs.8B12870  0.755
2018 Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, ... ... Nagorny P, et al. Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741. PMID 30648156 DOI: 10.1021/Acscentsci.8B00747  0.709
2018 Lee J, Wang S, Callahan M, Nagorny P. Copper(II)-Catalyzed Tandem Decarboxylative Michael/Aldol Reactions Leading to the Formation of Functionalized Cyclohexenones. Organic Letters. PMID 29560721 DOI: 10.1021/Acs.Orglett.8B00607  0.423
2018 Argüelles AJ, Sun S, Budaitis B, Nagorny P. Design, Synthesis and Application of Novel Chiral C2-symmetric Spiroketal-containing Ligands in Transition Metal Catalysis. Angewandte Chemie (International Ed. in English). PMID 29473275 DOI: 10.1002/Anie.201713304  0.39
2017 Bhattarai B, Nagorny P. Enantioselective Total Synthesis of Cannogenol-3-O-α-l-rhamnoside via Sequential Cu(II)-Catalyzed Michael Addition/Intramolecular Aldol Cyclization Reactions. Organic Letters. PMID 29244520 DOI: 10.1021/Acs.Orglett.7B03513  0.408
2017 Lee J, Borovika A, Khomutnyk Y, Nagorny P. Chiral phosphoric acid-catalyzed desymmetrizative glycosylation of 2-deoxystreptamine and its application to aminoglycoside synthesis. Chemical Communications (Cambridge, England). PMID 28744538 DOI: 10.1039/C7Cc05052F  0.42
2017 Tay JH, Argüelles AJ, DeMars MD, Zimmerman PM, Sherman DH, Nagorny P. Regiodivergent Glycosylations of 6-Deoxy-erythronolide B and Oleandomycin-Derived Macrolactones Enabled by Chiral Acid Catalysis. Journal of the American Chemical Society. PMID 28627172 DOI: 10.1021/Jacs.7B03198  0.618
2016 Kaplan W, Khatri HR, Nagorny P. Concise Enantioselective Total Synthesis of Cardiotonic Steroids 19-Hydroxysarmentogenin and Trewianin Aglycone. Journal of the American Chemical Society. PMID 27232585 DOI: 10.1021/Jacs.6B04029  0.739
2016 Nagorny P, Cichowicz N. New Strategy Based on Sequential Michael/Aldol Reactions for the Asymmetric Synthesis of Cardenolides Strategies and Tactics in Organic Synthesis. 12: 237-267. DOI: 10.1016/B978-0-08-100756-3.00009-1  0.482
2015 Khomutnyk YY, Arguelles AJ, Winschel GA, Sun Z, Zimmerman PM, Nagorny P. Studies of the Mechanism and Origins of Enantioselectivity for the Chiral Phosphoric Acid-Catalyzed Stereoselective Spi-roketalization Reactions. Journal of the American Chemical Society. PMID 26641317 DOI: 10.1021/Jacs.5B12528  0.617
2015 Larsen BJ, Sun Z, Lachacz E, Khomutnyk Y, Soellner MB, Nagorny P. Synthesis and Biological Evaluation of Lactimidomycin and Its Analogues. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26577990 DOI: 10.1002/Chem.201503527  0.438
2015 Cichowicz N, Kaplan W, Khomutnik I, Bhattarai B, Sun Z, Nagorny P. Concise Enantioselective Synthesis of Oxygenated Steroids via Sequential Copper(II)-Catalyzed Michael Addi-tion/Intramolecular Aldol Cyclization Reactions. Journal of the American Chemical Society. PMID 26491886 DOI: 10.1021/Jacs.5B08528  0.438
2015 Tay JH, Arguelles AJ, Nagorny P. Direct Interconversion of BINOL and H8-BINOL-Based Chiral Brønsted Acids Using Single-Step Red/Ox Manipulations. Organic Letters. 17: 3774-7. PMID 26196463 DOI: 10.1021/Acs.Orglett.5B01754  0.362
2015 Bhattarai B, Tay JH, Nagorny P. Thiophosphoramides as cooperative catalysts for copper-catalyzed arylation of carboxylates with diaryliodonium salts. Chemical Communications (Cambridge, England). 51: 5398-401. PMID 25525644 DOI: 10.1039/C4Cc08604J  0.4
2015 Tay JH, Nagorny P. 31P NMR Based Method for Determining Enantiopurity of Chiral Phosphoric Acids and Its Application to the BINOL- and H8-BINOL-Based Chiral Phosphoric Acid Thermal Racemization Studies Synlett. DOI: 10.1055/S-0035-1560547  0.355
2014 Sun Z, Winschel GA, Zimmerman PM, Nagorny P. Enantioselective synthesis of piperidines through the formation of chiral mixed phosphoric acid acetals: experimental and theoretical studies. Angewandte Chemie (International Ed. in English). 53: 11194-8. PMID 25196818 DOI: 10.1002/Anie.201405128  0.665
2013 Borovika A, Tang PI, Klapman S, Nagorny P. Thiophosphoramide-based cooperative catalysts for Brønsted acid promoted ionic Diels-Alder reactions. Angewandte Chemie (International Ed. in English). 52: 13424-8. PMID 24136865 DOI: 10.1002/Anie.201307133  0.368
2013 Mensah E, Camasso N, Kaplan W, Nagorny P. Chiral phosphoric acid directed regioselective acetalization of carbohydrate-derived 1,2-diols. Angewandte Chemie (International Ed. in English). 52: 12932-6. PMID 24123751 DOI: 10.1002/Anie.201304298  0.426
2013 Larsen BJ, Sun Z, Nagorny P. Synthesis of eukaryotic translation elongation inhibitor lactimidomycin via Zn(II)-mediated Horner-Wadsworth-Emmons macrocyclization. Organic Letters. 15: 2998-3001. PMID 23731327 DOI: 10.1021/Ol401186F  0.383
2013 Nagorny P, Sun Z, Winschel GA. Chiral phosphoric acid catalyzed stereoselective spiroketalizations Synlett. 24: 661-665. DOI: 10.1055/S-0032-1318098  0.478
2013 Borovika A, Nagorny P. Chiral Brønsted acid-catalyzed enantioselective ionic [2+4] cycloadditions Tetrahedron. 69: 5719-5725. DOI: 10.1016/J.Tet.2013.03.086  0.402
2012 Sun Z, Winschel GA, Borovika A, Nagorny P. Chiral phosphoric acid-catalyzed enantioselective and diastereoselective spiroketalizations. Journal of the American Chemical Society. 134: 8074-7. PMID 22545651 DOI: 10.1021/Ja302704M  0.444
2012 Cichowicz NR, Nagorny P. Synthesis of conjugated polyenes via sequential condensation of sulfonylphosphonates and aldehydes. Organic Letters. 14: 1058-61. PMID 22292860 DOI: 10.1021/Ol203431E  0.421
2012 Aussedat B, Fasching B, Johnston E, Sane N, Nagorny P, Danishefsky SJ. Total synthesis of the α-subunit of human glycoprotein hormones: toward fully synthetic homogeneous human follicle-stimulating hormone. Journal of the American Chemical Society. 134: 3532-41. PMID 22280541 DOI: 10.1021/Ja2111459  0.499
2012 Nagorny P, Sane N, Fasching B, Aussedat B, Danishefsky SJ. Probing the frontiers of glycoprotein synthesis: the fully elaborated β-subunit of the human follicle-stimulating hormone. Angewandte Chemie (International Ed. in English). 51: 975-9. PMID 22162182 DOI: 10.1002/Anie.201107482  0.445
2012 Borovika A, Nagorny P. Recent advances in the synthesis of natural 2-deoxy-β-glycosides Journal of Carbohydrate Chemistry. 31: 255-283. DOI: 10.1080/07328303.2012.663432  0.333
2011 Lecomte N, Njardarson JT, Nagorny P, Yang G, Downey R, Ouerfelli O, Moore MA, Danishefsky SJ. Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin. Proceedings of the National Academy of Sciences of the United States of America. 108: 15074-8. PMID 21808037 DOI: 10.1073/Pnas.1015247108  0.668
2010 Nagorny P, Krauss I, Njardarson JT, Perez L, Gaul C, Yang G, Ouerfelli O, Danishefsky SJ. Confirmation of the Structures of Synthetic Derivatives of Migrastatin in the Light of Recently Disclosed Crystallographically Based Claims. Tetrahedron Letters. 51: 3873-3875. PMID 20676392 DOI: 10.1016/J.Tetlet.2010.05.056  0.734
2010 Oskarsson T, Nagorny P, Krauss IJ, Perez L, Mandal M, Yang G, Ouerfelli O, Xiao D, Moore MA, Massagué J, Danishefsky SJ. Diverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analog. Journal of the American Chemical Society. 132: 3224-8. PMID 20155906 DOI: 10.1021/Ja9101503  0.719
2009 Rao Y, Li X, Nagorny P, Hayashida J, Danishefsky SJ. A Simple Method for the Conversion of Carboxylic Acids into Thioacids with Lawesson's Reagent. Tetrahedron Letters. 50: 6684-6686. PMID 20160926 DOI: 10.1016/J.Tetlet.2009.09.080  0.488
2009 Nagorny P, Kim WH, Wan Q, Lee D, Danishefsky SJ. On the emerging role of chemistry in the fashioning of biologics: synthesis of a bidomainal fucosyl GM1-based vaccine for the treatment of small cell lung cancer. The Journal of Organic Chemistry. 74: 5157-62. PMID 19555091 DOI: 10.1021/Jo900918M  0.581
2009 Nagorny P, Fasching B, Li X, Chen G, Aussedat B, Danishefsky SJ. Toward fully synthetic homogeneous beta-human follicle-stimulating hormone (beta-hFSH) with a biantennary N-linked dodecasaccharide. synthesis of beta-hFSH with chitobiose units at the natural linkage sites. Journal of the American Chemical Society. 131: 5792-9. PMID 19341309 DOI: 10.1021/Ja809554X  0.543
2007 Evans DA, Nagorny P, Reynolds DJ, McRae KJ. Enantioselective synthesis of oasomycin A, part II: synthesis of the C29-C46 subunit. Angewandte Chemie (International Ed. in English). 46: 541-4. PMID 17154212 DOI: 10.1002/Anie.200603654  0.554
2007 Evans DA, Nagorny P, McRae KJ, Reynolds DJ, Sonntag LS, Vounatsos F, Xu R. Enantioselective synthesis of oasomycin a, part I: synthesis of the C1-C12 and C13-C28 subunits. Angewandte Chemie (International Ed. in English). 46: 537-40. PMID 17154211 DOI: 10.1002/Anie.200603653  0.526
2007 Evans DA, Nagorny P, McRae KJ, Sonntag LS, Reynolds DJ, Vounatsos F. Enantioselective synthesis of oasomycin A, part III: fragment assembly and confirmation of structure. Angewandte Chemie (International Ed. in English). 46: 545-8. PMID 17154210 DOI: 10.1002/Anie.200603652  0.556
2007 Evans DA, Nagorny P, McRae KJ, Sonntag L-, Reynolds DJ, Vounatsos F. Synthesis of Oasomycin A Synfacts. 2007: 566-566. DOI: 10.1055/S-2007-968514  0.521
2007 Evans DA, Nagorny P, McRae KJ, Reynolds DJ, Sonntag L, Vounatsos F, Xu R. Enantioselective Synthesis of Oasomycin A (I). Part 1. Synthesis of the C1—C12 and C13—C28 Subunits. Cheminform. 38. DOI: 10.1002/chin.200721192  0.461
2007 Evans DA, Nagorny P, McRae KJ, Sonntag L, Reynolds DJ, Vounatsos F. Enantioselective Synthesis of Oasamycin A. Part 3. Fragment Assembly and Confirmation of Structure. Cheminform. 38. DOI: 10.1002/chin.200715203  0.432
2007 Evans DA, Nagorny P, Reynolds DJ, McRae KJ. Enantioselective Synthesis of Oasomycin A. Part 2. Synthesis of the C29—C46 Subunit. Cheminform. 38. DOI: 10.1002/chin.200715202  0.461
2006 Evans DA, Nagorny P, Xu R. Ceric ammonium nitrate promoted oxidation of oxazoles. Organic Letters. 8: 5669-71. PMID 17107099 DOI: 10.1021/Ol0624530  0.475
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