| Year |
Citation |
Score |
| 2018 |
Wagner FF, Benajiba L, Campbell AJ, Weïwer M, Sacher JR, Gale JP, Ross L, Puissant A, Alexe G, Conway A, Back M, Pikman Y, Galinsky I, DeAngelo DJ, Stone RM, et al. Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine. 10. PMID 29515000 DOI: 10.1126/Scitranslmed.Aam8460 |
0.301 |
|
| 2017 |
Epperly MW, Sacher JR, Krainz T, Zhang X, Wipf P, Liang M, Fisher R, Li S, Wang H, Greenberger JS. Effectiveness of Analogs of the GS-Nitroxide, JP4-039, as Total Body Irradiation Mitigators. In Vivo (Athens, Greece). 31: 39-43. PMID 28064218 DOI: 10.21873/Invivo.11022 |
0.417 |
|
| 2016 |
Krainz T, Gaschler MM, Lim C, Sacher JR, Stockwell BR, Wipf P. A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis. Acs Central Science. 2: 653-659. PMID 27725964 DOI: 10.1021/Acscentsci.6B00199 |
0.45 |
|
| 2015 |
Ma J, Lim C, Sacher JR, Van Houten B, Qian W, Wipf P. Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells. Bioorganic & Medicinal Chemistry Letters. PMID 26159482 DOI: 10.1016/J.Bmcl.2015.06.073 |
0.445 |
|
| 2015 |
Chauhan PS, Sacher JR, Weinreb SM. Synthesis of the tetracyclic skeleton of the Lycopodium alkaloid lycopladine H via a pivotal double hydroformylation/intramolecular reductive amination sequence. Organic Letters. 17: 806-8. PMID 25658603 DOI: 10.1021/Ol503571A |
0.53 |
|
| 2015 |
Ma J, Lim C, Sacher JR, Van Houten B, Qian W, Wipf P. Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells Bioorganic and Medicinal Chemistry Letters. DOI: 10.1016/j.bmcl.2015.06.073 |
0.365 |
|
| 2014 |
Escobales N, Nuñez RE, Jang S, Parodi-Rullan R, Ayala-Peña S, Sacher JR, Skoda EM, Wipf P, Frontera W, Javadov S. Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats. Journal of Molecular and Cellular Cardiology. 77: 136-46. PMID 25451170 DOI: 10.1016/J.Yjmcc.2014.10.009 |
0.406 |
|
| 2014 |
Skoda EM, Sacher JR, Kazancioglu MZ, Saha J, Wipf P. An uncharged oxetanyl sulfoxide as a covalent modifier for improving aqueous solubility. Acs Medicinal Chemistry Letters. 5: 900-4. PMID 25147611 DOI: 10.1021/Ml5001504 |
0.39 |
|
| 2014 |
Sacher JR, Weinreb SM. DISCUSSION ADDENDUM for: 2‐Trimethylsilylethanesulfonyl Chloride (SES‐Cl) Organic Syntheses. 34-43. DOI: 10.1002/0471264229.Os089.03 |
0.434 |
|
| 2013 |
Frantz MC, Skoda EM, Sacher JR, Epperly MW, Goff JP, Greenberger JS, Wipf P. Synthesis of analogs of the radiation mitigator JP4-039 and visualization of BODIPY derivatives in mitochondria. Organic & Biomolecular Chemistry. 11: 4147-53. PMID 23715589 DOI: 10.1039/C3Ob40489G |
0.467 |
|
| 2012 |
Sacher JR, Weinreb SM. Construction of the azocane (azacyclooctane) moiety of the Lycopodium alkaloid lycopladine H via an intramolecular hydroaminomethylation strategy. Organic Letters. 14: 2172-5. PMID 22486178 DOI: 10.1021/Ol3007277 |
0.519 |
|
| 2011 |
Sacher JR, Weinreb SM. Exploratory studies towards a total synthesis of the unusual bridged tetracyclic Lycopodium alkaloid lycopladine H. Tetrahedron. 67: 10203-10207. PMID 22125345 DOI: 10.1016/J.Tet.2011.04.016 |
0.541 |
|
| 2009 |
Evans MA, Sacher JR, Weinreb SM. Exploratory studies toward a total synthesis of the marine ascidian metabolite perophoramidine Tetrahedron. 65: 6712-6719. DOI: 10.1016/J.Tet.2008.10.060 |
0.519 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2015 |
Benajiba L, Wagner F, Ross L, Galinsky I, DeAngelo DJ, Gale J, Pan J, Zhang Y, Sacher J, Weiwer M, Stone RM, Holson E, Stegmaier K. Identification of a First in Class GSK3-Alpha Selective Inhibitor As a New Differentiation Therapy for AML Blood. 126: 870-870. DOI: 10.1182/Blood.V126.23.870.870 |
0.296 |
|
| 2016 |
Wagner FF, Bishop JA, Gale JP, Shi X, Walk M, Ketterman J, Patnaik D, Barker D, Walpita D, Campbell AJ, Nguyen S, Lewis M, Ross L, Weiwer M, An WF, ... ... Sacher JR, et al. Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-wide Selectivity and their Functional Effects. Acs Chemical Biology. PMID 27128528 DOI: 10.1021/Acschembio.6B00306 |
0.267 |
|
| 2018 |
Weiwer M, Xu Q, Gale JP, Lewis M, Campbell AJ, Schroeder FA, Van de Bittner GC, Walk M, Amaya A, Su P, Đorđević L, Sacher JR, Skepner A, Fei D, Dennehy K, et al. Functionally biased D2R antagonists: Targeting the β-arrestin pathway to improve antipsychotic treatment. Acs Chemical Biology. PMID 29485852 DOI: 10.1021/Acschembio.8B00168 |
0.261 |
|
| 2020 |
Reidenbach AG, Mesleh MF, Casalena D, Vallabh SM, Dahlin JL, Leed AJ, Chan AI, Usanov DL, Yehl JB, Lemke CT, Campbell AJ, Shah RN, Shrestha OK, Sacher JR, Rangel VL, et al. Multimodal small-molecule screening for human prion protein binders. The Journal of Biological Chemistry. PMID 32723867 DOI: 10.1074/Jbc.Ra120.014905 |
0.252 |
|
| 2020 |
Hinze L, Labrosse R, Degar J, Han T, Schatoff EM, Schreek S, Karim S, McGuckin C, Sacher JR, Wagner F, Stanulla M, Yuan C, Sicinska E, Giannakis M, Ng K, et al. Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy. Cancer Discovery. PMID 32703769 DOI: 10.1158/2159-8290.Cd-19-1472 |
0.249 |
|
| 2019 |
Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Stevenson KE, Neuberg DS, Orellana E, Stanulla M, Gregory RI, Bauer DE, Wagner FF, Stegmaier K, et al. Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias. Cancer Cell. 35: 664-676.e7. PMID 30991026 DOI: 10.1016/J.Ccell.2019.03.004 |
0.245 |
|
| 2021 |
He Y, Yang C, Wang Y, Sacher JR, Sims MM, Pfeffer LM, Miller DD. Novel structural-related analogs of PFI-3 (SRAPs) that target the BRG1 catalytic subunit of the SWI/SNF complex increase the activity of temozolomide in glioblastoma cells. Bioorganic & Medicinal Chemistry. 53: 116533. PMID 34863065 DOI: 10.1016/j.bmc.2021.116533 |
0.161 |
|
| 2022 |
Rohban MH, Fuller AM, Tan C, Goldstein JT, Syangtan D, Gutnick A, DeVine A, Nijsure MP, Rigby M, Sacher JR, Corsello SM, Peppler GB, Bogaczynska M, Boghossian A, Ciotti GE, et al. Virtual screening for small-molecule pathway regulators by image-profile matching. Cell Systems. PMID 36057257 DOI: 10.1016/j.cels.2022.08.003 |
0.124 |
|
| 2022 |
Wang Y, Yang C, Sims MM, Sacher JR, Raje M, Deokar H, Yue P, Turkson J, Buolamwini JK, Pfeffer LM. SS-4 is a highly selective small molecule inhibitor of STAT3 tyrosine phosphorylation that potently inhibits GBM tumorigenesis in vitro and in vivo. Cancer Letters. 533: 215614. PMID 35245627 DOI: 10.1016/j.canlet.2022.215614 |
0.12 |
|
| 2019 |
Hinze L, Pfirrmann M, Karim S, Degar J, McGuckin C, Vinjamur D, Sacher J, Orellana E, Gregory R, Bauer D, Wagner F, Stegmaier K, Stanulla M, Gutierrez A. GENOME-WIDE CRISPR-CAS9 SCREEN REVEALS SYNTHETIC LETHALITY OF WNT PATHWAY ACTIVATION AND ASPARAGINASE IN DRUG-RESISTANT ACUTE LEUKEMIAS Hemasphere. 3: 384. DOI: 10.1097/01.hs9.0000561716.06360.25 |
0.097 |
|
| 2022 |
Zhang YL, Moran SP, Allen A, Baez-Nieto D, Xu Q, Wang LA, Martenis WE, Sacher JR, Gale JP, Weïwer M, Wagner FF, Pan JQ. Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators. Acs Pharmacology & Translational Science. 5: 156-168. PMID 35311021 DOI: 10.1021/acsptsci.1c00233 |
0.069 |
|
| 2021 |
Shembel AC, Lee J, Sacher JR, Johnson AM. Characterization of Primary Muscle Tension Dysphonia Using Acoustic and Aerodynamic Voice Metrics. Journal of Voice : Official Journal of the Voice Foundation. PMID 34281751 DOI: 10.1016/j.jvoice.2021.05.019 |
0.017 |
|
| 2003 |
Hildebrandt L, Knispel R, Stry S, Sacher JR, Schael F. Antireflection-coated blue GaN laser diodes in an external cavity and Doppler-free indium absorption spectroscopy. Applied Optics. 42: 2110-8. PMID 12716152 |
0.015 |
|
| 2004 |
Hildebrandt L, Stry S, Knispel R, Sacher JR, Mann C, Fuchs F. Quantum cascade external cavity laser systems in the mid-infrared spectral range Osa Trends in Optics and Photonics Series. 96: 773-774. |
0.015 |
|
| 2007 |
Stry S, Sacher JR. Widely tunable ultra stable 1W two color THz laser source Proceedings of Spie - the International Society For Optical Engineering. 6472. DOI: 10.1117/12.701951 |
0.014 |
|
| 2003 |
Hildebrandt L, Knispel R, Stry S, Sacher JR. Optimization of the antireflection coating of blue GaN laser diodes and their characterization in an external cavity in Littrow and Littman-Metcalf configuration Conference On Lasers and Electro-Optics Europe - Technical Digest. 184. DOI: 10.1109/CLEOE.2003.1312245 |
0.01 |
|
| Hide low-probability matches. |