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William Howard Pirkle - Publications

Affiliations: 
Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
chiral recognition
Website:
http://www.chemistry.illinois.edu/faculty/William_Pirkle.html

272 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sheridan RP, Piras P, Sherer EC, Roussel C, Pirkle WH, Welch CJ. Mining Chromatographic Enantioseparation Data Using Matched Molecular Pair Analysis. Molecules (Basel, Switzerland). 21. PMID 27689987 DOI: 10.3390/Molecules21101297  0.461
2011 Carey JR, Kim E, Hong JH, Kang JS, Pirkle WH, Lee W. Investigation of chiral self-recognition of π-acidic 3,5-dinitrobenzoylleucine derivatives Bulletin of the Korean Chemical Society. 32: 4423-4426. DOI: 10.5012/Bkcs.2011.32.12.4423  0.522
2011 Lee W, Snyder SE, Volkers PI, Pirkle WH, Engebretson DA, Boulanger WA, Lin HS, Huang BS, Carey JR. Assessing chiral self-recognition using chiral stationary phases Tetrahedron. 67: 7143-7147. DOI: 10.1016/J.Tet.2011.06.103  0.744
2010 Pirkle WH, Lee W. Separation of the enantiomers of β-blockers using brush type chiral stationary phase derived from conformationally rigid α-amino β-lactam Bulletin of the Korean Chemical Society. 31: 620-623. DOI: 10.5012/Bkcs.2010.31.03.620  0.472
2010 Pirkle WH, Lee W. ChemInform Abstract: Separation of the Enantiomers of N-Benzyloxycarbonyl, 9-Fluorenylmethoxycarbonyl and Phthaloyl Protected α-Amino Acids and Their Ester or Amide Derivatives. Cheminform. 30: no-no. DOI: 10.1002/chin.199917197  0.401
2010 BRICE LJ, PIRKLE WH. ChemInform Abstract: Enantioselective Transport Through Liquid Membranes Cheminform. 28: no-no. DOI: 10.1002/chin.199736334  0.286
2010 PERRIN SR, PIRKLE WH. ChemInform Abstract: Commercially Available Brush-Type Chiral Selectors for the Direct Resolution of Enantiomers Cheminform. 24: no-no. DOI: 10.1002/chin.199302340  0.426
2010 Bayer E, Jennings WG, Majors RE, Kirkland JJ, Unger KK, Engelhardt H, Schomburg G, Pirkle WH, Welch CJ, Armstrong DW, Porath JO, Sjövall JB, Gehrke CW. History and Developments in Chromatographic Column Technology and Validation to 2001 Chromatography: a Science of Discovery. 199-267. DOI: 10.1002/9780470555729.ch6  0.227
2007 Snyder SE, Volkers PI, Engebretson DA, Lee W, Pirkle WH, Carey JR. Strong enantioselective self-recognition of a small chiral molecule. Organic Letters. 9: 2341-3. PMID 17488123 DOI: 10.1021/Ol070703M  0.693
2007 Perrin SR, Hauck W, Ndzie E, Blehaut J, Ludemann-Hombouger O, Nicoud RM, Pirkle WH. Purification of difluoromethylornithine by global process optimization: Coupling of chemistry and chromatography with enantioselective crystallization Organic Process Research and Development. 11: 817-824. DOI: 10.1021/op700118m  0.257
2005 Snyder SE, Carey JR, Shvets AB, Pirkle WH. Formation of stable Meisenheimer adduct ion pairs in apolar solvents: implications for stereoselective reactions. The Journal of Organic Chemistry. 70: 4073-81. PMID 15876099 DOI: 10.1021/Jo0502495  0.748
2005 Koscho ME, Pirkle WH. Investigation of a broadly applicable chiral selector used in enantioselective chromatography (Whelk-O 1) as a chiral solvating agent for NMR determination of enantiomeric composition Tetrahedron Asymmetry. 16: 3345-3351. DOI: 10.1016/J.Tetasy.2005.08.032  0.821
2005 Koscho ME, Spence PL, Pirkle WH. Chiral recognition in the solid state: Crystallographically characterized diastereomeric co-crystals between a synthetic chiral selector (Whelk-O1) and a representative chiral analyte Tetrahedron Asymmetry. 16: 3147-3153. DOI: 10.1016/J.Tetasy.2005.08.027  0.81
2005 Snyder SE, Carey JR, Pirkle WH. Biphasic enantioselective partitioning studies using small-molecule chiral selectors Tetrahedron. 61: 7562-7567. DOI: 10.1016/J.Tet.2005.05.060  0.703
2004 Job GE, Shvets A, Pirkle WH, Kuwahara S, Kosaka M, Kasai Y, Taji H, Fujita K, Watanabe M, Harada N. The effects of aromatic substituents on the chromatographic enantioseparation of diarylmethyl esters with the whelk-O1 chiral stationary phase. Journal of Chromatography. A. 1055: 41-53. PMID 15560478 DOI: 10.1016/J.Chroma.2004.08.001  0.71
2004 Naito J, Kosaka M, Sugito T, Watanabe M, Harada N, Pirkle WH. Enantioresolution of fluorinated diphenylmethanols and determination of their absolute configurations by X-Ray crystallographic and 1H NMR anisotropy methods. Chirality. 16: 22-35. PMID 14628296 DOI: 10.1002/Chir.10302  0.421
2003 Kosaka M, Sugito T, Kasai Y, Kuwahara S, Watanabe M, Harada N, Job GE, Shvet A, Pirkle WH. Enantioresolution and absolute configurations of chiral meta-substituted diphenylmethanols as determined by X-ray crystallographic and 1H NMR anisotropy methods. Chirality. 15: 324-8. PMID 12666239 DOI: 10.1002/Chir.10209  0.47
2002 Snyder SE, Pirkle WH. Enantioselective hydrolysis of N-acylated alpha-amino esters at a biphasic interface: tandem reaction kinetic resolution using a chiral complexing agent. Organic Letters. 4: 3283-6. PMID 12227769 DOI: 10.1021/Ol026517S  0.703
2002 Kosaka M, Kuwahara S, Watanabe M, Harada N, Job GE, Pirkle WH. Comparison of CD spectra of (2-methylphenyl)- and (2,6-dimethylphenyl)-phenylmethanols leads to erroneous absolute configurations. Enantiomer. 7: 213-7. PMID 12206501 DOI: 10.1080/10242430212878  0.387
2002 Wolf C, Pirkle WH. Conformational effects on the enantioselective recognition of 4-(3,5-dinitrobenzamido)-1,2,3,4-tetrahydrophenanthrene derivatives by a Naproxen-derived chiral stationary phase Tetrahedron. 58: 3597-3603. DOI: 10.1016/S0040-4020(02)00307-1  0.512
2002 Snyder SE, Shvets AB, Pirkle WH. Enantioselective nucleophilic aromatic substitution with small-molecule chiral selectors Helvetica Chimica Acta. 85: 3605-3615. DOI: 10.1002/1522-2675(200211)85:11<3605::Aid-Hlca3605>3.0.Co;2-W  0.794
2001 Pirkle WH, Snyder SE. Two-component chiral phase transfer catalysts: enantioselective esterification of an N-acylated amino acid. Organic Letters. 3: 1821-3. PMID 11405720 DOI: 10.1021/Ol015823N  0.735
2000 Hyun MH, Ryoo JJ, Pirkle WH. Experimental support differenciating two proposed chiral recognition models for the resolution of N-(3,5-dinitrobenzoyl)-alpha-arylalkylamines on high-performance liquid chromatography chiral stationary phases. Journal of Chromatography. A. 886: 47-53. PMID 10950274 DOI: 10.1016/S0021-9673(00)00485-4  0.508
2000 Hyun MH, Pirkle WH. Liquid chromatographic separation of the stereoisomers of thiazide diuretics. Journal of Chromatography. A. 876: 221-7. PMID 10823517 DOI: 10.1016/S0021-9673(00)00157-6  0.5
2000 Wolf C, Spence PL, Pirkle WH, Cavender DM, Derrico EM. Investigation of capillary electrochromatography with brush-type chiral stationary phases. Electrophoresis. 21: 917-24. PMID 10768777 DOI: 10.1002/(Sici)1522-2683(20000301)21:5<917::Aid-Elps917>3.0.Co;2-P  0.534
2000 Caldwell J, Berova N, Armstrong DW, Davankov V, Fell AF, Hacksell U, Koenig W, Lindner W, Okamoto Y, Pirkle WH, Schurig V, Testa B, Wainer IW, Welch CJ. Professor André Collet 1945-1999. Chirality. 12: 1. PMID 10671027 DOI: 10.1002/(Sici)1520-636X(2000)12:1<1::Aid-Chir1>3.0.Co;2-1  0.305
2000 Caldwell J, Berova N, Armstrong DW, Davankov V, Fell AF, Hacksell U, Koenig W, Lindner W, Okamoto Y, Pirkle WH, Schurig V, Testa B, Wainer IW, Welch CJ. Professor Andre collet 1945-1999 Chirality. 12: 1. PMID 10602259 DOI: 10.1002/(SICI)1520-636X(2000)12:1<1::AID-CHIR1>3.0.CO;2-1  0.186
2000 Caldwell J, Berova N, Armstrong DW, Davankov V, Fell AF, Hacksell U, Koenig W, Lindner W, Okamoto Y, Pirkle WH, Schurig V, Testa B, Wainer IW, Welch CJ, Misiti D. Erratum: Editor's note: Professor Andre Collet 1945-1999 Chirality. 12: 598-598. DOI: 10.1002/1520-636X(2000)12:7<598::Aid-Chir8>3.0.Co;2-9  0.309
1999 Pirkle WH, Koscho ME. Structural optimization of a chiral selector for use in preparative enantioselective chromatography Journal of Chromatography A. 840: 151-158. DOI: 10.1016/S0021-9673(99)00222-8  0.832
1998 Wolf C, Pirkle WH. Synthesis and evaluation of a copolymeric chiral stationary phase Journal of Chromatography A. 799: 177-184. DOI: 10.1016/S0021-9673(97)01063-7  0.56
1998 Pirkle WH, Spence PL. Chiral recognition of phthalides and lactams Chirality. 10: 430-433. DOI: 10.1002/(Sici)1520-636X(1998)10:5<430::Aid-Chir9>3.0.Co;2-9  0.539
1998 Pirkle WH, Liu Y, Welch CJ. Does C2 symmetry improve enantioselectivity? Enantiomer. 3: 477-483.  0.272
1997 Wolf C, Pirkle WH, Welch CJ, Hochmuth DH, Konig WA, CHee G.- L, Charlton JL. Determination of the enantiomerization barrier of arylnaphthalene lignans by cryogenic subcritical fluid chromatography and computer simulation Journal of Organic Chemistry. 62: 5208-5210. DOI: 10.1021/Jo9623705  0.348
1997 Pirkle WH, Gan KZ. A direct chromatographic separation of enantiomers chiral by virtue of isotopic substitution Tetrahedron Asymmetry. 8: 811-814. DOI: 10.1016/S0957-4166(97)00037-2  0.542
1997 Wolf C, Spence PL, Pirkle WH, Derrico EM, Cavender DM, Rozing GP. Enantioseparations by electrochromatography with packed capillaries Journal of Chromatography A. 782: 175-179. DOI: 10.1016/S0021-9673(97)00863-7  0.545
1997 Pirkle WH, Gan KZ. Facile and predictable means of separating the enantiomers of 5- arylhydantoins Journal of Chromatography A. 790: 65-71. DOI: 10.1016/S0021-9673(97)00761-9  0.535
1997 Wolf C, Pirkle WH. Enantioseparations by subcritical fluid chromatography at cryogenic temperatures Journal of Chromatography A. 785: 173-178. DOI: 10.1016/S0021-9673(97)00681-X  0.44
1997 Pirkle WH, Spence PL. Enantiodiffertiation of aryl-substituted heterocycles: A mechanistic study using γ-lactones Journal of Chromatography A. 775: 81-90. DOI: 10.1016/S0021-9673(97)00204-5  0.587
1997 Pirkle WH, Koscho ME. Predictable chromatographic separations of enantiomers: Aryl allenic acids and their derivatives Journal of Chromatography A. 761: 65-70. DOI: 10.1016/S0021-9673(96)00794-7  0.829
1997 Pirkle WH. On the minimum requirements for chiral recognition Chirality. 9: 103. DOI: 10.1002/(Sici)1520-636X(1997)9:2<103::Aid-Chir4>3.0.Co;2-I  0.527
1997 Wolf C, Pirkle WH. Enantiomer separation by supercritical fluid chromatography on packed columns Lc Gc: Liquid Chromatography, Gas Chromatography. 15: 352-363.  0.337
1997 Pirkle WH, Lee W, Welch CJ. Chromatographic separation of the enantiomers of 2-aryloxypropionic acids, esters and amides Enantiomer. 2: 423-431.  0.399
1996 Pirkle WH, Murray PG, Wilson SR. X-ray Crystallographic Evidence in Support of a Proposed Chiral Recognition Mechanism. The Journal of Organic Chemistry. 61: 4775-4777. PMID 11667410 DOI: 10.1021/Jo9512564  0.545
1996 Pirkle WH, Murray PG, Rausch DJ, McKenna ST. Intermolecular (1)H-(1)H Two-Dimensional Nuclear Overhauser Enhancements in the Characterization of a Rationally Designed Chiral Recognition System. The Journal of Organic Chemistry. 61: 4769-4774. PMID 11667409  0.299
1996 Pirkle WH, Brice LJ, Terfloth GJ. Liquid and subcritical CO2 separations of enantiomers on a broadly applicable polysiloxane chiral stationary phase Journal of Chromatography A. 753: 109-119. DOI: 10.1016/S0021-9673(96)00460-8  0.535
1996 Pirkle WH, Gan KZ, Brice LJ. The enhancement of enantioselectivity by halogen substituents Tetrahedron Asymmetry. 7: 2813-2816. DOI: 10.1016/0957-4166(96)00369-2  0.45
1996 Pirkle WH, Brice LJ, Widlanski TS, Roestamadji J. Resolution and determination of the enantiomeric purity and absolute configurations of α-aryl-α-hydroxymethanephosphonates Tetrahedron Asymmetry. 7: 2173-2176. DOI: 10.1016/0957-4166(96)00263-7  0.533
1996 Pirkle WH, Liu Y. On the relevance of face-to-edge π-π interactions to chiral recognition Journal of Chromatography A. 749: 19-24. DOI: 10.1016/0021-9673(96)00467-0  0.472
1996 Pirkle WH, Liu Y. Incremental development of chiral selectors for underivatized profens Journal of Chromatography A. 736: 31-38. DOI: 10.1016/0021-9673(95)01370-9  0.549
1996 Pirkle WH, Welch CJ. Some thoughts on the coupling of dissimilar chiral columns or the mixing of chiral stationary phases for the separation of enantiomers Journal of Chromatography A. 731: 322-326. DOI: 10.1016/0021-9673(95)01240-0  0.576
1996 Pirkle WH, Koscho ME, Wu Z. High-performance liquid chromatographic separation of the enantiomers of N-aryloxazolinones, N-aryl thiazolinones and their sulfur derivatives on a synthetic chiral stationary phase Journal of Chromatography A. 726: 91-97. DOI: 10.1016/0021-9673(95)00949-3  0.835
1996 Pirkle WH, Brice LJ, Caccamese S, Principato G, Failla S. Facile separation of the enantiomers of diethyl N-(aryl)-1-amino-1-arylmethanephosphonates on a rationally designed chiral stationary phase Journal of Chromatography A. 721: 241-246. DOI: 10.1016/0021-9673(95)00844-6  0.575
1996 Pirkle WH, Murray PG. Observations relevant to the differential intercalation of enantiomers between the strands of brush-type chiral stationary phases Journal of Chromatography A. 719: 299-305. DOI: 10.1016/0021-9673(95)00759-8  0.578
1995 Uzunov DP, Zivkovich I, Pirkle WH, Costa E, Guidotti A. Enantiomeric resolution with a new chiral stationary phase of 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide, a cognition-enhancing benzothiadiazine derivative. Journal of Pharmaceutical Sciences. 84: 937-42. PMID 7500277 DOI: 10.1002/jps.2600840807  0.447
1995 Pirkle WH, Selness SR. Chiral recognition studies: Intra- and intermolecular 1H{1H}-nuclear overhauser effects as effective tools in the study of bimolecular complexes The Journal of Organic Chemistry. 60: 3252-3256. DOI: 10.1021/Jo00115A048  0.4
1995 Villani C, Pirkle WH. Chromatographic resolution of the interconverting stereoisomers of hindered sulfinyl and sulfonyl naphthalene derivatives Tetrahedron: Asymmetry. 6: 27-30. DOI: 10.1016/0957-4166(94)00343-A  0.547
1995 Terfloth GJ, Pirkle WH, Lynam KG, Nicolas EC. Broadly applicable polysiloxane-based chiral stationary phase for high-performance liquid chromatography and supercritical fluid chromatography Journal of Chromatography A. 705: 185-194. DOI: 10.1016/0021-9673(95)00246-J  0.533
1995 Pirkle WH, Terfloth GJ. Naproxen-derived segmented and sidechain-modified polysiloxanes as chiral stationary phases Journal of Chromatography A. 704: 269-277. DOI: 10.1016/0021-9673(95)00223-A  0.545
1995 Villani C, Pirkle WH. Direct high-performance liquid chromatographic resolution of planar chiral tricarbonyl (η6-arene)-chromium(0) complexes Journal of Chromatography A. 693: 63-68. DOI: 10.1016/0021-9673(94)01041-C  0.53
1995 Pirkle WH, Selim AI. An improved version of an old fluorocarbinol chiral stationary phase Journal of High Resolution Chromatography. 18: 353-358. DOI: 10.1002/Jhrc.1240180606  0.556
1994 Pirkle WH, Murray PG, Yang Q. Chiral recognition of N-acyl-1-(2-fluorenyl)-1-aminoalkanes by π-acidic chiral stationary phases: A mechanistic view Journal of Liquid Chromatography. 17: 1665-1677. DOI: 10.1080/10826079408013449  0.593
1994 Pirkle WH, Liu Y. Design, synthesis, resolution, determination of absolute configuration, and evaluation of a chiral naproxen selector Journal of Organic Chemistry. 59: 6911-6916. DOI: 10.1021/Jo00102A013  0.483
1994 Pirkle WH, Welch CJ. Use of simultaneous face to face and face to edge π-π interactions to facilitate chiral recognition Tetrahedron: Asymmetry. 5: 777-780. DOI: 10.1016/S0957-4166(00)86225-4  0.501
1994 Pirkle WH, Bowen WE. Preparative separation of enantiomers using hollow-fiber membrane technology Tetrahedron: Asymmetry. 5: 773-776. DOI: 10.1016/S0957-4166(00)86224-2  0.431
1994 Pirkle WH, Spence PL, Lamm B, Welch CJ. Doubly tethered tertiary amide selectors. Modified version of Doyle et al.'s naproxen chiral stationary phase Journal of Chromatography A. 659: 69-74. DOI: 10.1016/0021-9673(94)85007-0  0.439
1994 Pirkle WH, Bowen WE, Vuong DV. Liquid chromatographic separation of the enantiomers of cyclic β-amino esters as their N-3,5-dinitrobenzoyl derivatives Journal of Chromatography A. 676: 297-302. DOI: 10.1016/0021-9673(94)80429-X  0.51
1994 Schleimer M, Pirkle WH, Schurig V. Enantiomer separation by high-performance liquid chromatography on polysiloxane-based chiral stationary phases Journal of Chromatography A. 679: 23-34. DOI: 10.1016/0021-9673(94)80308-0  0.576
1994 Pirkle WH, Welch CJ. Chromatographic and 1H NMR support for a proposed chiral recognition model Journal of Chromatography A. 683: 347-353. DOI: 10.1016/0021-9673(94)00477-3  0.599
1994 Pirkle WH, Bowen WE. Chiral stationary phase design: A study in optimization Journal of High Resolution Chromatography. 17: 629-633. DOI: 10.1002/Jhrc.1240170902  0.588
1994 Pirkle WH, Welch CJ, Wilson SR. Assignment of absolute configuration to an improved enantioselective naproxen selector Chirality. 6: 615-622. DOI: 10.1002/Chir.530060803  0.53
1993 Pirkle WH, Burke JA, Deming KC. The role of spatial complementarity in chiral recognition Journal of Liquid Chromatography. 16: 161-170. DOI: 10.1080/10826079308020904  0.489
1993 Pirkle WH, Murray PG, Burke JA. Use of homologous series of analytes as mechanistic probes to investigate the origins of enantioselectivity on two chiral stationary phases Journal of Chromatography A. 641: 21-29. DOI: 10.1016/0021-9673(93)83454-Z  0.601
1993 Pirkle WH, Murray PG. Chiral stationary phase design. Use of intercalative effects to enhance enantioselectivity Journal of Chromatography A. 641: 11-19. DOI: 10.1016/0021-9673(93)83453-Y  0.574
1993 Pirkle WH, Welch CJ, Zych AJ. Chromatographic investigation of the slowly interconverting atropisomers of hindered naphthamides Journal of Chromatography A. 648: 101-109. DOI: 10.1016/0021-9673(93)83291-Y  0.526
1993 Pirkle WH, Welch CJ, Yang Q. Comments on a report of the separation of the enantiomers of π-donor analytes on π-donor chiral stationary phases Journal of Chromatography A. 639: 329-332. DOI: 10.1016/0021-9673(93)80270-I  0.547
1993 Pirkle WH, Murray PG. An instance of temperature-dependent elution order of enantiomers from a chiral brush-type HPLC column Journal of High Resolution Chromatography. 16: 285-288. DOI: 10.1002/Jhrc.1240160505  0.538
1993 Pickard ST, Pirkle WH, Tabatabai M, Vogt W, Bohmer V. Dissymmetric calix[4]arenes: Optical resolution of some conformationally fixed derivatives Chirality. 5: 310-314. DOI: 10.1002/Chir.530050506  0.546
1992 Pirkle WH, Welch CJ. An improved chiral stationary phase for the chromatographic separation of underivatized naproxen enantiomers Journal of Liquid Chromatography. 15: 1947-1955. DOI: 10.1080/10826079208020869  0.568
1992 Pirkle WH, Welch CJ, Burke JA, Lamm B, Camilleri P, Schurig V, Jung M, Mayer S, Schmalzing D, Schleimer M, Taylor A, Blackledge CA, Nicholson JK, Williams DAR, Wilson ID, et al. Chirality Analytical Proceedings. 29: 225-234. DOI: 10.1039/AP9922900225  0.493
1992 Pirkle WH, Welch CJ, Lamm B. Design, synthesis, and evaluation of an improved enantioselective naproxen selector Journal of Organic Chemistry. 57: 3854-3860. DOI: 10.1021/Jo00040A026  0.517
1992 Pirkle WH, Welch CJ, Hyun MH. Concerning the role of face-to-edge π-π interactions in chiral recognition Journal of Chromatography A. 607: 126-130. DOI: 10.1016/0021-9673(92)87062-D  0.478
1992 Pirkle WH, Chang JP, Burke JA. Contribution of specifiable hydrophobic interactions to chiral recognition Journal of Chromatography A. 598: 1-6. DOI: 10.1016/0021-9673(92)85107-5  0.563
1992 Pirkle WH, Burke JA. Separation of the enantiomers of the 3,5-dinitrobenzamide derivatives of α-amino phosphonates on four chiral stationary phases Journal of Chromatography A. 598: 159-167. DOI: 10.1016/0021-9673(92)85044-T  0.588
1992 Welch CJ, Pirkle WH. Progress in the design of selectors for buckminsterfullerene Journal of Chromatography A. 609: 89-101. DOI: 10.1016/0021-9673(92)80152-K  0.456
1992 Pirkle WH, Welch CJ. Effect of superfluous remote polar functionality on chiral recognition Journal of Chromatography A. 589: 45-51. DOI: 10.1016/0021-9673(92)80004-E  0.509
1992 Pirkle WH, Heire R, Hyun MH. Preparation of α‐substituted α‐amino acids of high enantiomeric purity Chirality. 4: 302-307. DOI: 10.1002/Chir.530040508  0.505
1992 Pirkle WH, Heire R, Myung Ho Hyun. Preparation of α-substituted α-amino acids of high enantiomeric purity Chirality. 4: 302-307.  0.331
1991 Pirkle WH, Burke JA. Chiral stationary phase designed for beta-blockers. Journal of Chromatography. 557: 173-85. PMID 1683876 DOI: 10.1016/S0021-9673(01)87131-4  0.466
1991 Pirkle WH, Welch CJ. An investigation into the role of solvation in a well characterized chiral recognition system Journal of Liquid Chromatography. 14: 2027-2042. DOI: 10.1080/01483919108049672  0.557
1991 Pirkle WH, Welch CJ. A convenient void volume marker for several chiral HPLC columns Journal of Liquid Chromatography. 14: 1-8. DOI: 10.1080/01483919108049593  0.501
1991 Pirkle WH, Welch CJ. Chromatographic separation of underivatized naproxen enantiomers Journal of Liquid Chromatography. 14: 3387-3396. DOI: 10.1080/01483919108049397  0.608
1991 Pirkle WH, Welch CJ. An unusual effect of temperature on the chromatographic behavior of buckminsterfullerene Journal of Organic Chemistry. 56: 6973-6974. DOI: 10.1021/Jo00025A006  0.327
1991 Pirkle WH. Unusual effect of temperature on the retention of enantiomers on a chiral column Journal of Chromatography A. 558: 1-6. DOI: 10.1016/0021-9673(91)80106-Q  0.413
1991 Pirkle WH, Readnour RS. The influence of end-capping on the enantioselectivity of a chiral phase Chromatographia. 31: 129-132. DOI: 10.1007/BF02274559  0.49
1991 Pirkle WH, Deming KC, Burke JA. A chiral stationary phase which affords unusually high levels of enantioselectivity Chirality. 3: 183-187. DOI: 10.1002/Chir.530030308  0.597
1991 Pirkle WH, Readnour RS. Chromatographic approach to the measurement of the interstrand distance for some chiral bonded phases Analytical Chemistry. 63: 16-20.  0.4
1990 Pirkle WH, Murray PG. The separation of the enantiomers of a variety of non-steroidal anti-inflammatory drugs (NSAIDS) as their anilide derivatives using a chiral stationary phase Journal of Liquid Chromatography. 13: 2123-2134. DOI: 10.1080/01483919008049019  0.527
1990 PIRKLE WH, POCHAPSKY TC. ChemInform Abstract: Theory and Design of Chiral Stationary Phases for the Direct Chromatographic Separation of Enantiomers Cheminform. 21. DOI: 10.1002/chin.199021338  0.682
1989 Pirkle WH, Gruber JV. Synthesis of .gamma.-spiro lactones and .gamma.-spiro lactams. Diels-Alder adducts based on a 9,10-dihydro-9,10-ethanoanthracene structure The Journal of Organic Chemistry. 54: 3422-3428. DOI: 10.1021/Jo00275A031  0.382
1989 Pirkle WH, Burke JA, Wilson SR. X-ray crystallographic support of a chiral recognition model Journal of the American Chemical Society. 111: 9222-9223. DOI: 10.1021/Ja00208A016  0.404
1989 Pirkle WH, Doherty EM. Enantioselective transport through a silicone-supported liquid membrane Journal of the American Chemical Society. 111: 4113-4114. DOI: 10.1021/Ja00193A060  0.363
1989 Pirkle WH, Pochapsky TC. Considerations of chiral recognition relevant to the liquid chromatographic separation of enantiomers Chemical Reviews. 89: 347-362. DOI: 10.1021/Cr00092A006  0.719
1989 Pirkle WH, McCune JE. Discussion of a controversial chiral recognition model Journal of Chromatography A. 469: 67-75. DOI: 10.1016/S0021-9673(01)96441-6  0.561
1989 Pirkle WH, McCune JE. Separation of the enantiomers of N-protected α-amino acids as anilide and 3,5-dimethylanilide derivatives Journal of Chromatography A. 479: 419-423. DOI: 10.1016/S0021-9673(01)83357-4  0.512
1989 Pirkle WH, Chang Jp, Burke JA. Use of achiral ion-pairing reagents with chiral stationary phases Journal of Chromatography A. 479: 377-386. DOI: 10.1016/S0021-9673(01)83353-7  0.52
1989 Pirkle WH, McCune JE. Improved chiral stationary phase for the separation of the enantiomers of chiral acids as their anilide derivatives Journal of Chromatography A. 471: 271-281. DOI: 10.1016/S0021-9673(00)94175-X  0.603
1989 Pirkle WH, Burke JA. Preparation of chiral statonary phase from an ?-amino phosphonate Chirality. 1: 57-62. DOI: 10.1002/Chir.530010111  0.561
1989 Pirkle WH, Gruber JV. Synthesis of γ-spirolactones and γ-spirolactams. Diels-Alder adducts based on a 9,10-dihydro-9,10-ethanoanthracene structure Journal of Organic Chemistry. 54: 3422-3428.  0.286
1988 Pirkle WH, McCune JE. Liquid chromatographic separation of the enantiomers of chiral secondary alcohols as their a-naphthyl urethane derivatives Journal of Liquid Chromatography. 11: 2165-2173. DOI: 10.1080/01483918808069047  0.563
1988 Hyun MH, Baik IK, Pirkle WH. Liquid chromatographic resolution of enantiomeric dipeptides on the chiral stationary phase derived from (S)-1-(6,7-dimethyl-1-naphthyl)isobutylamine Journal of Liquid Chromatography. 11: 1249-1259. DOI: 10.1080/01483918808067170  0.501
1988 Pirkle WH, Sowin TJ, Salvadori P, Rosini C. Correlation of the circular dichroic spectra of 3-arylphthalides with absolute configuration and conformation Journal of Organic Chemistry. 53: 826-829. DOI: 10.1021/Jo00239A026  0.348
1988 Pirkle WH, Hamper BC. Chromatographic separation of the enantiomers of 1,3-dithiolane-1-oxides Journal of Chromatography A. 450: 199-210. DOI: 10.1016/S0021-9673(01)83907-8  0.58
1988 Pirkle WH, McCune JE. An improved chiral stationary phase for the facile separation of enantiomers Journal of Chromatography A. 441: 311-322. DOI: 10.1016/S0021-9673(01)83874-7  0.589
1988 Pirkle WH. Chromatographic separations of stereoisomers Journal of Chromatography A. 437: 458. DOI: 10.1016/S0021-9673(00)90422-9  0.467
1988 Pirkle WH, Pochapsky TC. Separation of the stereoisomers of a homologeous series of bis-amides on chiral stationary phases Chromatographia. 25: 652-654. DOI: 10.1007/BF02327666  0.719
1987 Pirkle WH, Alessi DM, Hyun MH, Pochapsky TC. Separation of some enantiomeric di- and tripeptides on chiral stationary phases. Journal of Chromatography. 398: 203-9. PMID 3654838 DOI: 10.1016/S0021-9673(01)96505-7  0.751
1987 Pirkle WH, Sowin TJ. Synthesis and separation of diastereomeric imino alcohol derivatives of chiral phthalides: A method for assignment of phthalide absolute configurations Journal of Organic Chemistry. 52: 3011-3017. DOI: 10.1021/Jo00390A012  0.509
1987 Pirkle WH, Reno DS. Extension of chromatographically derived molecular recognition concepts to first-order asymmetric transformations Journal of the American Chemical Society. 109: 7189-7190. DOI: 10.1021/Ja00257A047  0.397
1987 Pirkle WH, Pochapsky TC. Chiral molecular recognition in small bimolecular systems: A spectroscopic investigation into the nature of diastereomeric complexes Journal of the American Chemical Society. 109: 5975-5982. DOI: 10.1021/Ja00254A014  0.645
1987 Pirkle WH, Hamper BC. Chapter 7 The Direct Preparative Resolution Of Enantiomers By Liquid Chromatography On Chiral Stationary Phases Journal of Chromatography Library. 38: 235-287. DOI: 10.1016/S0301-4770(08)60370-X  0.564
1987 Pirkle WH, Sowin TJ. Direct liquid chromatographic separation of phthalide enantiomers Journal of Chromatography A. 387: 313-321. DOI: 10.1016/S0021-9673(01)94534-0  0.594
1987 Pirkle WH, Mahler GS, Pochapsky TC, Hyun MH. Direct chromatographic separation of enantiomeric diol derivatives Journal of Chromatography A. 388: 307-314. DOI: 10.1016/S0021-9673(01)94492-9  0.727
1987 Hyun MH, Pirkle WH. Preparation and evaluation of a chiral stationary phase bearing both π-acidic and -basic sites Journal of Chromatography A. 393: 357-365. DOI: 10.1016/S0021-9673(01)94234-7  0.539
1987 Pirkle WH, Sowin TJ. Design, preparation and performance of a phthalide-based chiral stationary phase Journal of Chromatography A. 396: 83-92. DOI: 10.1016/S0021-9673(01)94044-0  0.562
1987 Pirkle WH, Däppen R, Reno DS. Applications for racemic versions of chiral stationary phases Journal of Chromatography A. 407: 211-216. DOI: 10.1016/S0021-9673(01)92619-6  0.574
1987 Pirkle WH, Däppen R. Reciprocity in Chiral Recognition. Comparison of several chiral stationary phases Journal of Chromatography A. 404: 107-115. DOI: 10.1016/S0021-9673(01)86841-2  0.583
1987 Röder W, Ruffing F, Schomburg G, Pirkle WH. Chiral SFC-separations using polymer-coated open tubular fused silica columns. Comparison of enantiomeric selectivity in SFC and LC using the same stationary phase of the Pirkle type Journal of High Resolution Chromatography. 10: 665-667. DOI: 10.1002/Jhrc.1240101209  0.492
1986 Hart DJ, Lee CS, Pirkle WH, Hyon MH, Tsipouras A. Asymmetric synthesis of .beta.-lactams and the carbapenem antibiotic (+)-PS-5. Journal of the American Chemical Society. 108: 6054-6. PMID 22175380 DOI: 10.1021/Ja00279A072  0.36
1986 Griffith OW, Campbell EB, Pirkle WH, Tsipouras A, Hyun MH. Liquid chromatographic separation of enantiomers of beta-amino acids using a chiral stationary phase. Journal of Chromatography. 362: 345-52. PMID 3760049 DOI: 10.1016/S0021-9673(01)86986-7  0.418
1986 Smith DF, Pirkle WH. Stereoselective analysis of racemic psychotropic compounds by HPLC on chiral stationary phase. Psychopharmacology. 89: 392-3. PMID 3088667 DOI: 10.1007/BF00174381  0.468
1986 Pirkle WH, Mahler G, Hyun MH. Separation of the enantiomers of 3,5-dinitrophenyl carbamates and 3,5-dinitrophenyl ureas Journal of Liquid Chromatography. 9: 443-453. DOI: 10.1080/01483918608076646  0.491
1986 Pirkle WH, Pochapsky TC, Mahler GS, Corey DE, Reno DS, Alessi DM. Useful and easily prepared chiral stationary phases for the direct chromatographic separation of the enantiomers of a variety of derivatized amines, amino acids, alcohols, and related compounds Journal of Organic Chemistry. 51: 4991-5000. DOI: 10.1021/Jo00375A045  0.707
1986 Stipanovic RD, McCormick JP, Schlemper EO, Hamper BC, Shinmyozu T, Pirkle WH. Corroboration of techniques for assigning absolute configuration: Lacinilene C methyl ether as an exemplary study Journal of Organic Chemistry. 51: 2500-2504. DOI: 10.1021/Jo00363A018  0.346
1986 Pirkle WH, Pochapsky TC. Intermolecular proton[proton] nuclear Overhauser effects in diastereomeric complexes: support for a chromatographically derived chiral recognition model Journal of the American Chemical Society. 108: 5627-5628. DOI: 10.1021/Ja00278A045  0.673
1986 Pirkle WH, Tsipouras A, Hyun MH, Hart DJ, Lee CS. Use of chiral stationary phases for the chromatographic determination of enantiomeric purity and absolute configuration of some β-lactams Journal of Chromatography A. 358: 377-384. DOI: 10.1016/S0021-9673(01)90351-6  0.4
1986 Pirkle WH, Pochapsky TC. Generation of extreme selectivity in chiral recognition Journal of Chromatography A. 369: 175-177. DOI: 10.1016/S0021-9673(00)90111-0  0.653
1986 Pirkle WH, Pochapsky TC. Preparation of N-(2-naphthyl)-2-amino acids and esters of high enantiomeric purity Journal of Organic Chemistry. 51: 102-105. DOI: 10.1002/Chin.198625201  0.657
1986 Pirkle WH, Pochapsky TC. Intermolecular 1H{1H} nuclear overhauser effects in diastereomeric complexes: Support for a chromatographically derived chiral recognition model Journal of the American Chemical Society. 108: 5627-5628.  0.615
1986 Hart DJ, Lee CS, Pirkle WH, Hyon MH, Tsipouras A. Asymmetric synthesis of β-lactams and the carbapenem antibiotic (+)-PS-5 Journal of the American Chemical Society. 108: 6054-6056.  0.271
1986 Pirkle WH, Pochapsky TC. A new, easily accessible reciprocal chiral stationary phase for the chromatographic separation of enantiomers Journal of the American Chemical Society. 108: 352-354.  0.708
1985 Pirkle WH, Tsipouras A. 3,5-dinitrobenzoyl amino acid esters. Broadly applicable chiral solvating agents for NMR determination of enantiomeric purity Tetrahedron Letters. 26: 2989-2992. DOI: 10.1016/S0040-4039(00)98599-X  0.511
1985 Pirkle WH, Hyun MH. Preparation and use of hydantion-based chiral stationary phases Journal of Chromatography A. 322: 309-320. DOI: 10.1016/S0021-9673(01)97690-3  0.575
1985 Pirkle WH, Hyun MH. α-arylalkylamine-derived chiral stationary phases. Evaluation of urea linkages Journal of Chromatography A. 322: 295-307. DOI: 10.1016/S0021-9673(01)97689-7  0.568
1985 Pirkle WH, Hyun MH. Reversed-phase chromatographic resolution of N-(3,5-dinitrobezoyl)- α-amino acids on chiral stationary phases Journal of Chromatography A. 322: 287-293. DOI: 10.1016/S0021-9673(01)97688-5  0.591
1985 Pirkle WH, Pochapsky TC, Mahler GS, Field RE. Chromatographic separation of the enantiomers of 2-carboalkoxyindolines and N-aryl-α-amino esters on chiral stationary phases derived from N-(3,5-dinitrobenzoyl)-α-amino acids Journal of Chromatography A. 348: 89-96. DOI: 10.1016/S0021-9673(01)92442-2  0.745
1985 Pirkle WH, Tsipouras A, Sowin TJ. Preparative separation of enantiomers by flash chromatography Journal of Chromatography A. 319: 392-395. DOI: 10.1016/S0021-9673(01)90577-1  0.51
1985 H.Pirkle W, Ho Hyun M. Effect of intertstrand distance upon chiral recognition by a chiral stationary phase Journal of Chromatography A. 328: 1-9. DOI: 10.1016/S0021-9673(01)87372-6  0.549
1985 Griffith OW, Campbell EB, Pirkle WH. Resolution and racemization of β-amino acids Federation Proceedings. 44: No. 4692.  0.272
1984 Pirkle WH, Hyun MH, Tsipouras A, Hamper BC, Banks B. A rational approach to the design of highly effective chiral stationary phases for the liquid chromatographic separation of enantiomers. Journal of Pharmaceutical and Biomedical Analysis. 2: 173-81. PMID 16867745 DOI: 10.1016/0731-7085(84)80068-0  0.588
1984 Kim IC, Waller DP, Marcelle GB, Cordell GA, Fong HH, Pirkle WH, Pilla L, Matlin SA. Comparative in vitro spermicidal effects of (+/-)-gossypol, (+)-gossypol, (-)-gossypol and gossypolone. Contraception. 30: 253-9. PMID 6509980 DOI: 10.1016/0010-7824(84)90088-X  0.205
1984 Pirkle WH, Hyun MH. A chiral stationary phase for the facile resolution of amino acids, amino alcohols, and amines as the N-3,5-dinitrobenzoyl derivatives Journal of Organic Chemistry. 49: 3043-3046. DOI: 10.1021/Jo00191A001  0.497
1984 Pirkle WH, Welch CJ, Mahler GS, Meyers AI, Fuentes LM, Boes M. Chromatographic separation of the enantiomers of N-acylated heterocyclic amines The Journal of Organic Chemistry. 49: 2504-2506. DOI: 10.1021/Jo00187A043  0.48
1984 Pirkle WH, Myung HH, Bank B. A rational approach to the design of highly-effective chiral stationary phases Journal of Chromatography A. 316: 585-604. DOI: 10.1016/S0021-9673(00)96185-5  0.572
1984 Pirkle WH, Tsipouras A. Direct liquid chromatographic separation of benzodiazepinone enantiomers Journal of Chromatography A. 291: 291-298. DOI: 10.1016/S0021-9673(00)95031-3  0.584
1984 Pirkle WH, Robertson MR, Hyun MH. A liquid chromatographic method for resolving chiral lactams as their diastereomeric ureide derivatives Journal of Organic Chemistry. 49: 2433-2437. DOI: 10.1002/Chin.198449168  0.526
1984 Pirkle WH, Welch CJ, Mahler GS, Meyers AI, Fuentes LM, Boes M. Chromatographic Separation Of The Enantiomers Of N-Acylated Heterocyclic Amines Cheminform. 15. DOI: 10.1002/Chin.198449061  0.48
1984 Pirkle WH, Welch CJ, Hyun MH. A Chiral Recognition Model For The Chromatographic Resolution Of N‐Acylated 1‐Aryl‐1‐Aminoalkanes Cheminform. 15. DOI: 10.1002/Chin.198427083  0.541
1984 Pirkle WH, Welch CJ. Chromatographic separation of the enantiomers of acylated amines on chiral stationary phases Journal of Organic Chemistry. 49: 138-140. DOI: 10.1002/Chin.198425157  0.592
1984 Pirkle WH, Welch CJ, Mahler GS, Meyers AI, Fuentes LM, Boes M. Chromatographic separation of the enantiomers of N-acylated heterocyclic amines Journal of Organic Chemistry. 49: 2504-2506.  0.395
1983 Pirkle WH, Welch CJ, Hyun MH. A chiral recognition model for the chromatographic resolution of N-acylated 1-aryl-1-aminoalkanes Journal of Organic Chemistry. 48: 5022-5026. DOI: 10.1021/Jo00173A045  0.514
1983 Pirkle WH, Finn JM. Useful routes to 9-anthryl ethers and sulfides Journal of Organic Chemistry. 48: 2779-2780. DOI: 10.1021/Jo00164A034  0.366
1983 Pirkle WH, Simmons KA. Improved chiral derivatizing agents for the chromatographic resolution of racemic primary amines Journal of Organic Chemistry. 48: 2520-2527. DOI: 10.1021/Jo00163A019  0.507
1983 Pirkle WH. Stacking of amide dipoles as an alternate to hydrogen bonds in chiral recognition rationales Tetrahedron Letters. 24: 5707-5708. DOI: 10.1016/S0040-4039(00)94178-9  0.451
1983 ALLENMARK S, NIELSEN L, PIRKLE WH. ChemInform Abstract: ENANTIOSELECTIVE LIQUID-CHROMATOGRAPHIC RETENTION OF A SERIES OF SULFOXIDES AND N-SUBSTITUTED SULFOXIMINES ON CHIRAL STATIONARY PHASES Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198350063  0.517
1982 Pirkle WH, Finn JM. Preparative resolution of racemates on a chiral liquid chromatography column Journal of Organic Chemistry. 47: 4037-4040. DOI: 10.1021/Jo00142A007  0.534
1982 PIRKLE WH, HOOVER DJ. ChemInform Abstract: NMR Chiral Solvating Agents (111 Literaturhinweise). Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198247369  0.416
1982 PIRKLE WH, SCHREINER JL. ChemInform Abstract: CHIRAL HPLC (HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC) STATIONARY PHASES. 4. SEPARATION OF THE ENANTIOMERS OF BI-β NAPHTHOLS AND ANALOGS Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198216107  0.474
1981 Pirkle WH, Schreiner JL. Chiral HPLC (high-performance liquid chromatographic) stationary phases. 4. Separation of the enantiomers of bi-.beta. naphthols and analogs The Journal of Organic Chemistry. 46: 4988-4991. DOI: 10.1021/Jo00337A033  0.528
1981 Pirkle WH, Simmons KA. Nuclear magnetic resonance determination of enantiomeric composition and absolute configuration of amines, alcohols, and thiols with α-[1-(9-anthryl)-2,2,2-trifluoroethoxy]acetic acid as a chiral derivatizing agent Journal of Organic Chemistry. 46: 3239-3246. DOI: 10.1021/Jo00329A019  0.46
1981 Pirkle WH, Finn JM. Chiral high-pressure liquid chromatographic stationary phases. 3. General resolution of arylalkylcarbinols Journal of Organic Chemistry. 46: 2935-2938. DOI: 10.1021/Jo00327A019  0.507
1981 Pirkle WH, Finn JM, Schreiner JL, Hamper BC. A widely useful chiral stationary phase for the high-performance liquid chromatography separation of enantiomers Journal of the American Chemical Society. 103: 3964-3966. DOI: 10.1002/Chin.198141059  0.55
1981 PIRKLE WH, ADAMS PE. ChemInform Abstract: ENANTIOMERICALLY PURE LACTONES. 3. SYNTHESIS OF AND STEREOSPECIFIC CONJUGATE ADDITIONS TO α,β-UNSATURATED LACTONES Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198107257  0.323
1981 Pirkle WH, Schreiner JL. Chiral high-pressure liquid chromatographic stationary phases. 4. Separation of the enantiomers of bi-β-naphthols and analogues Journal of Organic Chemistry. 46: 4988-4991.  0.445
1980 Pirkle WH, Adams PE. Enantiomerically pure lactones. 3. Synthesis of and stereospecific conjugate additions to .alpha.,.beta.-unsaturated lactones The Journal of Organic Chemistry. 45: 4117-4121. DOI: 10.1021/Jo01309A009  0.383
1980 Pirkle WH, Adams PE. Enantiomerically pure lactones. 2. Approaches to cis or trans multicyclic lactones Journal of Organic Chemistry. 45: 4111-4117. DOI: 10.1021/Jo01309A008  0.355
1980 Pirkle WH, Hoover DJ. Stereospecific alkylation of 3,5,5-trisubstituted-4-hydroxy-1-p-tosyl-2-pyrazolines by trimethylaluminum. An efficient synthesis of 3,3,5,5-tetrasubstituted-1-pyrazolin-4-ones Journal of Organic Chemistry. 45: 3407-3413. DOI: 10.1021/Jo01305A007  0.41
1980 Pirkle WH, Rinaldi PL. Use of liquid-crystal-induced circular dichroism for determination of absolute configuration of alcohols and oxaziridines Journal of Organic Chemistry. 45: 1379-1382. DOI: 10.1021/Jo01296A007  0.589
1980 Pirkle WH, House DW, Finn JM. Broad spectrum resolution of optical isomers using chiral high-performance liquid chromatographic bonded phases Journal of Chromatography A. 192: 143-158. DOI: 10.1016/S0021-9673(00)81849-X  0.596
1980 Pirkle WH, Adams PE. Enantiomerically pure lactones. 3. Synthesis of and stereospecific conjugate additions to α,β-unsaturated lactones Journal of Organic Chemistry. 45: 4117-4121.  0.314
1979 Pirkle WH, Adams PE. Broad-spectrum synthesis of enantiomerically pure lactones. 1. Synthesis of sex pheromones of the carpenter bee, rove beetle, japanese beetle, black-tailed deer, and oriental hornet Journal of Organic Chemistry. 44: 2169-2175. DOI: 10.1021/Jo01327A029  0.43
1979 Pirkle WH, Rinaldi PL. Synthesis and enantiomeric purity determination of the optically active epoxide disparlure, sex pheromone of the gypsy moth Journal of Organic Chemistry. 44: 1025-1028. DOI: 10.1021/Jo01321A001  0.604
1979 Pirkle WH, Simmons KA, Boeder CW. Dynamic NMR studies of diastereomeric carbamates: Implications toward the determination of relative configuration by NMR Journal of Organic Chemistry. 44: 4891-4896. DOI: 10.1021/Jo00394A031  0.38
1979 Pirkle WH, Rinaldi PL, Simmons KA. Binding of lanthanide shift reagents to oxaziridines Journal of Magnetic Resonance (1969). 34: 251-264. DOI: 10.1016/0022-2364(79)90001-5  0.59
1979 Pirkle WH, House DW. Chiral high-pressure liquid chromatographic stationary phases. 1. Separation of the enantiomers of sulfoxides, amines, amino acids, alcohols, hydroxy acids, lactones, and mercaptans Journal of Organic Chemistry. 44: 1957-1960.  0.435
1978 Pirkle W, Rinaldi P. Correction. Nuclear Magnetic Resonance Determination of Enantiomeric Compositions of Oxaziridines Using Chiral Solvating Agents. The Journal of Organic Chemistry. 43: 5027-5027. DOI: 10.1021/jo00420a611  0.579
1978 Pirkle WH, Rinaldi PL. Nuclear magnetic resonance determination of absolute configuration and enantiomeric compositions of chiral oxaziridines using chiral solvating agents Journal of Organic Chemistry. 43: 4475-4480. DOI: 10.1021/Jo00417A018  0.653
1978 Pirkle WH, Rinaldi PL. General method for the synthesis of high enantiomeric purity chiral epoxides Journal of Organic Chemistry. 43: 3803-3807. DOI: 10.1021/Jo00414A001  0.675
1978 Pirkle WH, Gravel PL. Cyclic diacylhydrazyl radicals. 2. Persistent cyclic diacylhydrazyl radicals from urazoles and pyrazolidine-3,5-diones The Journal of Organic Chemistry. 43: 808-815. DOI: 10.1021/Jo00399A004  0.297
1978 PIRKLE WH, GRAVEL PL. ChemInform Abstract: CYCLIC DIACYLHYDRAZYL RADICALS. 2. PERSISTENT CYCLIC DIACYLHYDRAZYL RADICALS FROM URAZOLES AND PYRAZOLIDINE-3,5-DIONES Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197830128  0.203
1978 Pirkle WH, Gravel PL. Persistent cyclic diacylhydrazyl radicals from urazoles and pyrazolidine-3,5-diones Journal of Organic Chemistry. 43: 808-815.  0.188
1978 Pirkle WH, Boeder CW. Synthesis and absolute configuration of (-)-methyl (E)-2,4,5-tetradecatrienoate, the sex attractant of the male dried bean weevil Journal of Organic Chemistry. 43: 2091-2093.  0.265
1978 Pirkle WH, Boeder CW. Preparation of simple chiral allenes. Reaction of propargylic carbamates with lithium dialkylcuprates Journal of Organic Chemistry. 43: 1950-1952.  0.39
1978 Pirkle WH, Adams PE. Synthesis of the carpenter bee pheromone. Chiral 2-methyl-5-hydroxyhexanoic acid lactones Journal of Organic Chemistry. 43: 378-379.  0.411
1977 Pirkle WH, Hauske JR, Eckert CA, Scott BA. High pressure assisted synthesis. Evidence for nucleophilic displacement on 2,2,2-trifluoro-1-phenylethyl tosylate Journal of Organic Chemistry. 42: 3101-3103. DOI: 10.1021/Jo00438A035  0.256
1977 Pirkle WH, Sikkenga DL. The use of chiral solvating agents for nuclear magnetic resonance determination of enantiomeric purity and absolute configuration of lactones. Consequences of three-point interactions Journal of Organic Chemistry. 42: 1370-1374. DOI: 10.1021/Jo00428A023  0.444
1977 Pirkle WH, Gravel PL. Cyclic diacylhydrazyl radicals from 1,3,4-oxadiazolidine-2,5-diones, pyridazine-3,6-diones, and phthalazine-1,4-diones Journal of Organic Chemistry. 42: 1367-1369. DOI: 10.1021/Jo00428A022  0.31
1977 Pirkle WH, Sikkenga DL, Pavlin MS. Nuclear magnetic resonance determination of enantiomeric composition and absolute configuration of γ-lactones using chiral 2,2,2-trifluoro-1-(9-anthryl)ethanol Journal of Organic Chemistry. 42: 384-387. DOI: 10.1021/Jo00422A061  0.4
1977 Pirkle WH, Gravel PL. Synthesis of 1-.alpha.-cumyl-1,2,3,6-tetrahydropyridazine-3,6-dione The Journal of Organic Chemistry. 42: 296-297. DOI: 10.1021/Jo00422A028  0.347
1977 PIRKLE WH, GRAVEL PL. ChemInform Abstract: SYNTHESIS OF 1-α-CUMYL-1,2,3,6-TETRAHYDROPYRIDAZINE-3,6-DIONE Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197722243  0.32
1977 Pirkle WH, Hauske JR. Design of chiral derivatizing agents for the chromatographic resolution of optical isomers. Asymmetric synthesis of some chiral fluoroalkylated amines Journal of Organic Chemistry. 42: 2436-2439.  0.454
1977 Pirkle WH, Rinaldi PL. Nuclear magnetic resonance determination of enantiomeric compositions of oxaziridines using chiral solvating agents Journal of Organic Chemistry. 42: 3217-3219.  0.578
1977 Pirkle WH, Rinaldi PL. Asymmetric synthesis in liquid crystals: Independence of stereochemistry on the handedness of the cholesteric liquid crystal [8] Journal of the American Chemical Society. 99: 3510-3511.  0.561
1977 Pirkle WH, Boeder CW. Estimation of allene optical purities by nuclear magnetic resonance Journal of Organic Chemistry. 42: 3697-3700.  0.217
1977 Pirkle WH, Hauske JR. Broad spectrum methods for the resolution of optical isomers. A discussion of the reasons underlying the chromatographic separability of some diastereomeric carbamates Journal of Organic Chemistry. 42: 1839-1844.  0.314
1977 Pirkle WH, Hauske JR. Trichlorosilane-induced cleavage. A mild method for retrieving carbinols from carbamates Journal of Organic Chemistry. 42: 2781-2782.  0.209
1977 Pirkle WH, Rinaldi PL. Reevaluation of the use of peroxycamphoric acid as an asymmetric oxidizing agent Journal of Organic Chemistry. 42: 2080-2082.  0.532
1977 Pirkle WH, Gravel PL. Synthesis of 1-α-cumyl-1,2,3,6-tetrahydropyridazine-3,6-dione Journal of Organic Chemistry. 42: 296-297.  0.304
1976 Pirkle WH, Gravel PL. Synthesis of monosubstituted 1,3,4-oxadiazolidine-2,5-diones Journal of Organic Chemistry. 41: 3763-3765. DOI: 10.1021/Jo00885A027  0.411
1976 Pirkle WH, Eckert CA, Turner WV, Scott BA, McKendry LH. High pressure thermal and the photosensitized dimerizations of 2-pyrones Journal of Organic Chemistry. 41: 2495-2496. DOI: 10.1021/Jo00876A034  0.292
1976 Pirkle WH, Hauske JR. Conformational control by carbinyl hydrogens. Implications and applications Journal of Organic Chemistry. 41: 801-805. DOI: 10.1021/Jo00867A012  0.324
1976 Pirkle WH, Hoekstra MS. Chiral nuclear magnetic resonance solvating agents. Resolution, determination of enantiomeric purity, and assignment of absolute configuration of cyclic and acyclic sulfinate esters Journal of the American Chemical Society. 98: 1832-1839. DOI: 10.1021/Ja00423A031  0.468
1976 Pirkle WH, Hoekstra MS, Miller WH. Electronic effects in asymmetric induction. reaction of para-substituted phenylsulfinyl chlorides with S-(+)-1-(1-naphthyl)-2,2,2-trifluoroethanol Tetrahedron Letters. 17: 2109-2112. DOI: 10.1016/S0040-4039(00)93131-9  0.378
1976 Pirkle WH, Sikkenga DL. Resolution of optical isomers by liquid chromatography Journal of Chromatography A. 123: 400-404. DOI: 10.1016/S0021-9673(00)82210-4  0.416
1976 Pirkle WH, Eckert CA, Turner WV, Scott BA, McKendry LH. High pressure thermal and photosensitized dimerizations of 2-pyrones Journal of Organic Chemistry. 41: 2495-2496.  0.176
1975 Pirkle WH, Sikkenga DL. Use of achiral shift reagents to indicate relative stabilities of diastereomeric solvates Journal of Organic Chemistry. 40: 3430-3434. DOI: 10.1021/Jo00911A028  0.376
1975 Pirkle WH, Turner WV. Specific oxygen-18 labeling and mass spectral fragmentation of 2-pyrone. Carbon monoxide vs. carbon sulfide (CS) loss on fragmentation of sulfur analogs of 2-pyrones The Journal of Organic Chemistry. 40: 1644-1646. DOI: 10.1021/jo00899a030  0.212
1975 Pirkle WH, Hoekstra MS. Carbon-13 nonequivalence of enantiomers in chiral solvents Journal of Magnetic Resonance (1969). 18: 396-400. DOI: 10.1016/0022-2364(75)90140-7  0.48
1975 Pirkle WH, Turner WV. Specific oxygen-18 labeling and mass spectral fragmentation of 2-pyrone. CO vs. CS loss on fragmentation of sulfur analogs of 2-pyrones Journal of Organic Chemistry. 40: 1644-1646.  0.191
1975 Pirkle WH, Turner WV. Rearrangements of 2-pyrones and pyran-2-thiones involving 1,5-sigmatropic hydrogen shifts Journal of Organic Chemistry. 40: 1617-1620.  0.253
1974 Pirkle WH, Pavlin MS. Determination of the enantiomeric purity of compound chiral by virtue of C-13 labelling Journal of the Chemical Society, Chemical Communications. 274-275. DOI: 10.1039/C39740000274  0.362
1974 Pirkle WH, Hoekstra MS. Automated liquid chromatography. Synthesis of a broad-spectrum resolving agent and resolution of 1-(1-naphthyl)-2,2,2-trifluoroethanol The Journal of Organic Chemistry. 39: 3904-3906. DOI: 10.1021/jo00940a023  0.369
1974 Gravel PL, Pirkle WH. Non-aryl hydrazyls. I. Synthesis, isolation, and characterization of 1-.alpha.-cumyl-4-methylurazolyl Journal of the American Chemical Society. 96: 3335-3336. DOI: 10.1021/Ja00817A062  0.365
1974 Whitney TA, Pirkle WH. Determination of absolute configurations by NMR. Stereochemistry of the base-catalyzed decarboxylation of 2-methyl-2,3-dihydrobenzothiophene-2-carboxylic acid 1-dioxide Tetrahedron Letters. 15: 2299-2300. DOI: 10.1016/S0040-4039(01)92238-5  0.426
1974 Pirkle WH, Beare SD, Muntz RL. Assignment of absolute configuration of sulfoxides by NMR. A solvation model Tetrahedron Letters. 15: 2295-2298. DOI: 10.1016/S0040-4039(01)92237-3  0.382
1974 PIRKLE WH, BEARE SD, MUNTZ RL, WHITNEY TA. ChemInform Abstract: ASSIGNMENT OF ABSOLUTE CONFIGURATION OF SULFOXIDES BY NMR, A SOLVATION MODEL, DETERMINATION OF ABSOLUTE CONFIGURATIONS BY NMR, STEREOCHEMISTRY OF THE BASE-CATALYZED DECARBOXYLATION OF 2-METHYL-2,3-DIHYDROBENZOTHIOPHENE-2-CARBOXYLIC AC Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197440253  0.421
1974 GRAVEL PL, PIRKLE WH. ChemInform Abstract: NON-ARYL HYDRAZYLS PART 1, SYNTHESIS, ISOLATION AND CHARACTERIZATION OF 1ALPHA-CUMYL-4-METHYLURAZOLYL Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197429156  0.379
1974 Turner WV, Pirkle WH. Carbon magnetic resonance spectra of 2-pyrones Journal of Organic Chemistry. 39: 1935-1937.  0.225
1974 Pirkle WH, Anderson RW. An automated preparative liquid chromatography system Journal of Organic Chemistry. 39: 3901-3903.  0.343
1974 Gravel PL, Pirkle WH. Non-aryl hydrazyls. I. Synthesis, isolation, and characterization of 1-α-cumyl-4-methylurazolyl [17] Journal of the American Chemical Society. 96: 3335-3336.  0.315
1974 Pirkle WH, Hoekstra MS. An example of automated liquid chromatography. Synthesis of a broad-spectrum resolving agent and resolution of 1-(1-naphthyl)-2,2,2-trifluoroethanol Journal of Organic Chemistry. 39: 3904-3906.  0.372
1972 PIRKLE WH, LUNSFORD WB. ChemInform Abstract: ENERGETIK DER CIS-TRANS-UMWANDLUNG EINES BICYCLO(5,1,0)OCTAN-SYST. Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/chin.197251095  0.227
1972 KAINOSHO M, AJISAKA K, PIRKLE WH, BEARE SD. ChemInform Abstract: VERWENDUNG VON CHIRALEN LOESUNGSMITTELN ODER LANTHANID-VERSCHIEBUNGSREAGENZIEN ZUR UNTERSCHEIDUNG DER MESO- VON DEN D- ODER L-DIASTEREOMEREN Chemischer Informationsdienst. 3. DOI: 10.1002/chin.197244099  0.215
1972 MUNTZ RL, PIRKLE WH, PAUL IC. ChemInform Abstract: BESTIMMUNG DER ABSOLUTEN KONFIG. VON (-)-N-AETHYL-N-METHYL-ANILIN-N-OXID DURCH ROENTGENSTRUKTURANALYSE, MOLEKULARGEOMETRIE DES N-OXID-SALZES Chemischer Informationsdienst. 3. DOI: 10.1002/Chin.197221116  0.242
1972 Kainosho M, Ajisaka K, Pirkle WH, Beare SD. The use of chiral solvents or lanthanide shift reagents to distinguish meso from d or l diastereomers [25] Journal of the American Chemical Society. 94: 5924-5926.  0.357
1972 Pirkle WH, Limsford WB. Energetics of the cis-trans interconversion of a bicyclo[5.1.0]octane system [38] Journal of the American Chemical Society. 94: 7201-7202.  0.202
1972 Muntz RL, Pirkle WH, Paul LC. Determination of the absolute configuration of (-)-N-ethyl-N-methylaniline oxide by X-ray analysis: The molecular geometry of an N-oxide salt Journal of the Chemical Society, Perkin Transactions 2. 483-488.  0.244
1971 PIRKLE WH, MUNTZ RL, PAUL IC. ChemInform Abstract: CHIRALE NMR-LOESUNGSMITTEL 11. MITT. METHODE ZUR BESTIMMUNG DER ABSOLUTEN KONFIG. VON CHIRALEN N,N-DIALKYL-ARYLAMINOXIDEN Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197134095  0.359
1971 PIRKLE WH, SETO H, TURNER WV. ChemInform Abstract: SIGMATROPE 1,5-WASSERSTOFF-VERSCHIEBUNG EINSCHLIESSENDE GERUESTUMLAGERUNGEN VON PYRONEN-(2) Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197106160  0.376
1971 Pirkle WH, Muntz RL, Paul IC. Chiral nuclear magnetic resonance solvents. XI. A method for determining the absolute configuration of chiral N,N-dialkylarylamine oxides [27] Journal of the American Chemical Society. 93: 2817-2819.  0.381
1970 Pirkle WH. Comments on the use of nuclear magnetic resonance spectroscopy to assign absolute configurations of diastereomeric salts Journal of the Chemical Society D: Chemical Communications. 1525-1526. DOI: 10.1039/C29700001525  0.243
1970 Pirkle WH, Stickler JC. Nitrogen-backboned polymers. I Journal of the American Chemical Society. 92: 7497-7499. DOI: 10.1021/Ja00728A058  0.307
1970 Pirkle WH, Seto HG, Turner WV. Skeletal rearrangements of 2-pyrones involving 1,5-sigmatropic hydrogen shifts Journal of the American Chemical Society. 92: 6984-6985. DOI: 10.1021/Ja00726A053  0.355
1970 Pirkle WH, Seto H, Turner WV. Skeletal rearrangements of 2-pyrones involving 1,5-sigmatropic hydrogen shifts [15] Journal of the American Chemical Society. 92: 6984-6985.  0.249
1970 Pirkle WH, Stickler JC. Nitrogen-backboned polymers. I [23] Journal of the American Chemical Society. 92: 7497-7499.  0.193
1969 Pirkle WH, Dines MB. Bromination of 2-pyrone The Journal of Organic Chemistry. 34: 2239-2244. DOI: 10.1021/Jo01260A001  0.363
1969 Pirkle WH, Beare SD, Burlingame TG. Optically active nuclear magnetic resonance solvents. VIII. Resolution of 2,2,2-trifluoro-1-phenylethanol The Journal of Organic Chemistry. 34: 470-471. DOI: 10.1021/Jo01254A051  0.354
1969 Pirkle WH, Beare SD, Muntz RL. Optically active solvents for nuclear magnetic resonance. X. Enantiomeric nonequivalence of sulfinamides, sulfinates, sulfites, thiosulfinates, phosphine oxides, and amine oxides Journal of the American Chemical Society. 91: 4575-4575. DOI: 10.1021/ja01044a058  0.238
1969 Pirkle WH, Smith SG, Koser GF. Stereospecificity and wavelength dependence in the photochemical rearrangement of spiro[2.5]octa-4,7-dien-6-ones to quinone methides Journal of the American Chemical Society. 91: 1580-1582. DOI: 10.1021/Ja01034A077  0.288
1969 Chamot D, Pirkle WH. Static bridged carbonium ions. Direct nuclear magnetic resonance observation of stereochemically distinct ions Journal of the American Chemical Society. 91: 1569-1571. DOI: 10.1021/Ja01034A070  0.317
1969 Pirkle WH, McKendry LH. Photochemical reactions of 2-pyrone and thermal reactions of the 2-pyrone photoproducts Journal of the American Chemical Society. 91: 1179-1186. DOI: 10.1021/ja01033a025  0.189
1969 Pirkle WH, Dines M. On the nitration of 2-pyrone Journal of Heterocyclic Chemistry. 6: 313-315. DOI: 10.1002/jhet.5570060308  0.204
1969 Pirkle WH, Dines M. NMR spectra of 2-pyrone and 2-pyrone derivatives Journal of Heterocyclic Chemistry. 6: 1-3. DOI: 10.1002/Jhet.5570060101  0.392
1968 Pirkle WH, Chamot D, Day WA. 1,2-Dimethyl-5,7-di-tert-butylspiro[2,5]octa-1,4,7-trien-6-one. Synthesis and chemistry The Journal of Organic Chemistry. 33: 2152-2153. DOI: 10.1021/Jo01269A113  0.434
1968 Pirkle WH, Beare SD. Optically active solvents in nuclear magnetic resonance spectroscopy. VII. Direct determination of optical purities and correlations of absolute configurations of sulfoxides Journal of the American Chemical Society. 90: 6250-6251. DOI: 10.1021/ja01024a073  0.254
1968 Pirkle WH, Koser GF. Halonium ylides. I Journal of the American Chemical Society. 90: 3598-3600. DOI: 10.1021/ja01015a075  0.292
1968 Pirkle WH, Dines M. Structure of electron impact fragments. The C4H4O radical cation from 2-pyrone Journal of the American Chemical Society. 90: 2318-2323. DOI: 10.1021/Ja01011A020  0.306
1968 Pirkle W, Beare S. Nuclear magnetic resonance spectroscopy in optically active solvents. V. The determination of the absolute configuration of (+)-α-hydroxy-α-trifluoromethylphenylacetic acid Tetrahedron Letters. 9: 2579-2582. DOI: 10.1016/S0040-4039(00)89701-4  0.4
1968 Pirkle W, Koser G. Photolysis of hindered spiro[2.5]octa-4,7-dien-6-ones Tetrahedron Letters. 9: 129-133. DOI: 10.1016/S0040-4039(00)75573-0  0.434
1968 Pirkle W, Burlingame T, Beare S. Optically active nmr solvents VI. The determination of optical purity and absolute configuration of amines. Tetrahedron Letters. 9: 5849-5852. DOI: 10.1016/S0040-4039(00)75421-9  0.376
1968 Pirkle W, McKendry L. The multiplicity of the reactive 2-pyrone excited states. Tetrahedron Letters. 9: 5279-5282. DOI: 10.1016/S0040-4039(00)75363-9  0.288
1968 Pirkle W, Koser G. Halonium ylids II Tetrahedron Letters. 9: 3959-3962. DOI: 10.1016/S0040-4039(00)72376-8  0.284
1967 Koser GF, Pirkle WH. Improved synthesis of spiro [2.5] octa-4,7-dien-6-ones The Journal of Organic Chemistry. 32: 1992-1994. DOI: 10.1021/Jo01281A065  0.417
1967 Pirkle WH, Beare SD. Nonequivalence of the nuclear magnetic resonance spectra of enantiomers in optically active solvents. IV. Assignment of absolute configuration Journal of the American Chemical Society. 89: 5485-5487. DOI: 10.1021/ja00997a051  0.279
1967 Kalish R, Pirkle WH. Synthesis of allenes by cycloelimination reactions Journal of the American Chemical Society. 89: 2781-2782. DOI: 10.1021/ja00987a077  0.261
1967 Pirkle W, Burlingame T. Nonequivalence of the nuclear magnetic reasonance spectra of enantiomers in optically active solvents III Tetrahedron Letters. 8: 4039-4042. DOI: 10.1016/S0040-4039(01)89733-1  0.38
1967 Corey E, Pirkle W. Tricyclo[23,6.1.1.0]pyran-2-one Tetrahedron Letters. 8: 5255-5256. DOI: 10.1016/S0040-4039(01)89655-6  0.255
1966 Stickler JC, Pirkle WH. An Improved Synthesis of 1,2,4-Triazoline-3,5-diones The Journal of Organic Chemistry. 31: 3444-3445. DOI: 10.1021/jo01348a532  0.303
1966 Burlingame TG, Pirkle WH. The Nonequivalence of Physical Properties of Enantiomers in Optically Active Solvents. Differences in Proton Magnetic Resonance Spectra. II Journal of the American Chemical Society. 88: 4294-4294. DOI: 10.1021/ja00970a055  0.261
1965 Pirkle WH, Gates M. The Derivation of Hydroaromatic Morphinans and Isomorphinans from Natural Sources* The Journal of Organic Chemistry. 30: 1769-1773. DOI: 10.1021/Jo01017A014  0.345
1965 Pirkle WH. Structure of Electron Impact Fragments. The C4H4O Cation from 2-Pyrone Journal of the American Chemical Society. 87: 3022-3023. DOI: 10.1021/ja01091a052  0.204
1964 Pirkle WH, Zabriskie JL. The Replacement of Phenolic Hydroxyl Groups by Hydrogen The Journal of Organic Chemistry. 29: 3124-3126. DOI: 10.1021/jo01033a540  0.224
1961 Van Tamelen EE, Dewey RS, Lease MF, Pirkle WH. SELECTIVITY AND MECHANISM OF DIIMIDE REDUCTIONS Journal of the American Chemical Society. 83: 4302-4302. DOI: 10.1021/ja01481a057  0.217
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